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Search results 3001 to 3100 out of 3237 for Pax2

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Hits by Strain

Type Details Score
Allele
Pax2<tm1Mbu> | MGI:1858000
Name: paired box 2; targeted mutation 1, Meinrad Busslinger
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
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Allele
Krd | MGI:1861657
 
Name: kidney and retinal defects
Allele Type: Transgenic
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Allele
Tg(Pax2-cre)10Shwl | MGI:3613796
Name: transgene insertion 10, William Shawlot
Allele Type: Transgenic
Attribute String: Recombinase
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Allele
Tg(Pax2-EGFP)MR165Gsat | MGI:4847300
Name: transgene insertion MR165, GENSAT Project at Rockefeller University
Allele Type: Transgenic
Attribute String: Reporter
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Publication
22292091 | J:184222
First Author: Gall JM
Year: 2012
Journal: PLoS One
Title: Role of mitofusin 2 in the renal stress response.
Volume: 7
Issue: 1
Pages: e31074
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Publication
12588986 | J:82319
First Author: Cho EA
Year: 2003
Journal: Mol Cell Biol
Title: BRCT domain-containing protein PTIP is essential for progression through mitosis.
Volume: 23
Issue: 5
Pages: 1666-73
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Publication
26744420 | J:229465
First Author: Starnes LM
Year: 2016
Journal: Genes Dev
Title: A PTIP-PA1 subcomplex promotes transcription for IgH class switching independently from the associated MLL3/MLL4 methyltransferase complex.
Volume: 30
Issue: 2
Pages: 149-63
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Publication
18353733 | J:168190
First Author: Göhler T
Year: 2008
Journal: DNA Repair (Amst)
Title: PTIP/Swift is required for efficient PCNA ubiquitination in response to DNA damage.
Volume: 7
Issue: 5
Pages: 775-87
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Protein Domain
IPR037886 | Paxip1
Type: Family
Description: This entry includes PAX-interacting protein 1 (PTIP or Swift) and chromatin modification-related protein eaf1 (from Aspergillus fumigatus). PTIP is involved in the DNA damage response and is an adaptor protein for the ATM/ATR kinases. PTIP contains five BRCT domains with which it interacts with the activation domain of the transcription factor Pax2 []. Knockout of PTIP prevent ubiquitination of proliferating cell nuclear antigen (PCNA), and monoubiquitination of PCNA enables translesion synthesis by specialized DNA polymerases to replicate damaged DNA []. Cells without PTIP are unable to progress through mitosis []. PTIP is a component of the MLL2/MLL3 complex [], but a PTIP-PA1 subcomplex functions independently of the MLL3/MLL4 complex to mediate transcription during class switch recombination, important for generating antibody diversity []. In Saccharomyces cerevisiae, EAF1 is a component of the NuA4 histone acetyltransferase complex involved in acetylation of nucleosomal histone H4 and H2A [].
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Strain
MGI:5562549 | C3.Cg-Pax2<1Neu>/Ieg
Attribute String: congenic, mutant strain, spontaneous mutation
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Strain
MGI:3695035 | C3.129P2-Pax2<tm1Mbu>
Attribute String: targeted mutation, mutant strain, congenic
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Strain
MGI:6281034 | B6.Cg-Pde6b<+> Krd/Boc
Attribute String: chromosome aberration, congenic, deletion, insertion
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Strain
MGI:2165116 | C3.Cg-Pde6b<+> Krd/J
Attribute String: congenic, mutant strain, deletion
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Publication
9000048 | J:37854
First Author: Bedell MA
Year: 1997
Journal: Genes Dev
Title: Mouse models of human disease. Part II: recent progress and future directions.
Volume: 11
Issue: 1
Pages: 11-43
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Publication
10087301 | J:54055
First Author: Ji W
Year: 1999
Journal: Mamm Genome
Title: Identification of genes within the Krd deletion on mouse chromosome 19.
Volume: 10
Issue: 4
Pages: 399-401
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Publication
9748274 | J:50327
First Author: Nomura H
Year: 1998
Journal: J Biol Chem
Title: Identification of PKDL, a novel polycystic kidney disease 2-like gene whose murine homologue is deleted in mice with kidney and retinal defects.
Volume: 273
Issue: 40
Pages: 25967-73
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Allele
Tg(Pax2-cre)1Akg | MGI:3046196
Name: transgene insertion 1, Andrew K Groves
Allele Type: Transgenic
Attribute String: Recombinase
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Strain
MGI:5004268 | STOCK Tg(Pax2-EGFP)MR165Gsat/Mmucd
Attribute String: mutant stock, transgenic
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Allele
Pax6<tm2.1(Pax6_i5a,Pax2)Xzh> | MGI:5512912
Name: paired box 6; targeted mutation 2.1, Xin Zhang
Allele Type: Targeted
Attribute String: Inserted expressed sequence
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Genotype
Genotype
Symbol: Pax2/Pax2
Background: C3.129P2-Pax2
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Krd/Krd
Background: involves: C3H/He * C57BL/6 * YBR/Ki
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Krd/Krd<+>
Background: involves: C3H/He * C57BL/6 * YBR/Ki
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Pax2<1Neu>/Pax2<+>
Background: involves: 102 * C3H
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Pax2<1Neu>/Pax2<1Neu>
Background: involves: 102 * C3H
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Pax2<1Neu>/Pax2<1Neu>
Background: involves: 102
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Pax2<1Neu>/Pax2<+>
Background: involves: 102 * C57BL/6
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Pax2<1Neu>/Pax2<+>
Background: involves: 102
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Pax2/Pax2<+>
Background: C3.129P2-Pax2
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Pax2/Pax2
Background: involves: 129P2/OlaHsd * C3H/He
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Pax2/Pax2<+>
Background: involves: 129P2/OlaHsd * C3H/He
Zygosity: ht
Has Mutant Allele: true
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Publication
23950737 | J:202692
 
First Author: Zuccotti A
Year: 2013
Journal: Front Mol Neurosci
Title: L-type CaV1.2 deletion in the cochlea but not in the brainstem reduces noise vulnerability: implication for CaV1.2-mediated control of cochlear BDNF expression.
Volume: 6
Pages: 20
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Publication
26476841 | J:311507
First Author: Chumak T
Year: 2016
Journal: Mol Neurobiol
Title: BDNF in Lower Brain Parts Modifies Auditory Fiber Activity to Gain Fidelity but Increases the Risk for Generation of Central Noise After Injury.
Volume: 53
Issue: 8
Pages: 5607-27
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Strain
MGI:3696461 | C3.129P2-Pax2<tm1Mbu> Pax2<tm2(Pax5)Mbu>
Attribute String: congenic, mutant strain, targeted mutation
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Genotype
Genotype
Symbol: Pax2/Pax2
Background: C3.129P2-Pax2 Pax2
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Pax2<1Neu>/Pax2<+> Wt1/Wt1<+>
Background: involves: 102 * 129S4/SvJae * C57BL/6
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Pax6/Pax6<+>
Background: involves: 129S6/SvEvTac * C57BL/6 * FVB/N
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Pax6/Pax6
Background: involves: 129S6/SvEvTac * C57BL/6 * FVB/N
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Pax2<1Neu>/Pax2<+> Pkd1/Pkd1
Background: involves: 101 * 129S4/SvJae * C3H
Zygosity: cx
Has Mutant Allele: true
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Strain
MGI:5651193 | (C57BLKS-Pitx3<ak> x C3H-Pax2<1Neu>)F1-Pitx3<ak> Pax2<1Neu>
Attribute String: F1 hybrid, mutant stock
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Publication
35020897 | J:321503
 
First Author: Meuser M
Year: 2022
Journal: Development
Title: FGFR2 signaling enhances the SHH-BMP4 signaling axis in early ureter development.
Volume: 149
Issue: 1
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Strain
MGI:6147067 | B6.CD1-Tg(Pax2-cre)1Akg/Rbrc
Attribute String: mutant strain, congenic, transgenic
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Strain
MGI:4358079 | STOCK Tg(Pax2-cre)1Akg/Mmnc
Attribute String: mutant stock, transgenic
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Publication
26542959 | J:230587
First Author: Motojima M
Year: 2016
Journal: Mamm Genome
Title: Conditional knockout of Foxc2 gene in kidney: efficient generation of conditional alleles of single-exon gene by double-selection system.
Volume: 27
Issue: 1-2
Pages: 62-9
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Publication
25885434 | J:229250
First Author: Cui J
Year: 2015
Journal: PLoS One
Title: Analysis of Kif5b expression during mouse kidney development.
Volume: 10
Issue: 4
Pages: e0126002
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Genotype
Genotype
Symbol: Pax2/Pax2<+> Pax8/Pax8<+>
Background: involves: 129P2/OlaHsd * C3H/He * C57BL/6
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Pax2/Pax2 Pax8/Pax8
Background: C3.Cg-Pax2 Pax8
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Bmp4/Bmp4 Tg(Pax2-cre)1Dje/?
Background: involves: 129S2/SvPas * 129S6/SvEvTac * Black Swiss * C57BL/6 * SJL
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Bhlhe22/Bhlhe22 Tg(Pax2-cre)1Akg/?
Background: involves: 129
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Pax2/Pax2<+> Pax8/Pax8
Background: involves: 129P2/OlaHsd * C3H/He * C57BL/6
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Pdss2/Pdss2 Tg(Pax2-cre)1Akg/?
Background: involves: 129 * C57BL/6N * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Pax2<1Neu>/Pax2<+> Tg(Hoxb7-EGFP)33Cos/?
Background: involves: 102 * C57BL/6 * CBA * CD-1
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Krd/Krd<+> Pax5/Pax5
Background: involves: 129S2/SvPas * C3H/He * C57BL/6J
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Krd/Krd<+> Pax5/Pax5<+>
Background: involves: 129S2/SvPas * C3H/He * C57BL/6J
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tbx2/Tbx2 Tg(Pax2-cre)10Shwl/?
Background: involves: C57BL/6 * NMRI * SJL
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tbx3/Tbx3 Tg(Pax2-cre)10Shwl/?
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * NMRI * SJL
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(Pax2-cre)1Akg/?
Background: involves: CD-1
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Fgfr1/? Fgfr2/Fgfr2 Tg(Pax2-cre)10Shwl/?
Background: involves: 129S4/SvJaeSor * 129X1/SvJ * C57BL/6 * SJL
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tbx2/Tbx2 Tbx3/Tbx3 Tg(Pax2-cre)1Akg/?
Background: involves: Swiss Webster
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Fst/Fst Tg(Pax2-cre)1Akg/?
Background: involves: 129S7/SvEvBrd
Zygosity: cn
Has Mutant Allele: true
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Protein
A0A0G2JE02
Organism: Mus musculus/domesticus
Length: 92  
Fragment?: false
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Publication
10595508 | J:58564
First Author: Schulte D
Year: 1999
Journal: Neuron
Title: Misexpression of the Emx-related homeobox genes cVax and mVax2 ventralizes the retina and perturbs the retinotectal map.
Volume: 24
Issue: 3
Pages: 541-53
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Publication
23639443 | J:197142
First Author: Chang JC
Year: 2013
Journal: Dev Cell
Title: Prdm13 mediates the balance of inhibitory and excitatory neurons in somatosensory circuits.
Volume: 25
Issue: 2
Pages: 182-95
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Publication
8521821 | J:29948
First Author: Stuart ET
Year: 1995
Journal: EMBO J
Title: Loss of p53 function through PAX-mediated transcriptional repression.
Volume: 14
Issue: 22
Pages: 5638-45
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Publication
19171890 | J:356428
First Author: Brown JD
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: Expression profiling during ocular development identifies 2 Nlz genes with a critical role in optic fissure closure.
Volume: 106
Issue: 5
Pages: 1462-7
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Publication
22723694 | J:185663
First Author: Zuccotti A
Year: 2012
Journal: J Neurosci
Title: Lack of brain-derived neurotrophic factor hampers inner hair cell synapse physiology, but protects against noise-induced hearing loss.
Volume: 32
Issue: 25
Pages: 8545-53
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Publication
38243766 | J:359100
First Author: Marchetta P
Year: 2024
Journal: FASEB J
Title: Dysfunction of specific auditory fibers impacts cortical oscillations, driving an autism phenotype despite near-normal hearing.
Volume: 38
Issue: 2
Pages: e23411
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Publication
17292869 | J:118633
 
First Author: Rocha-Sanchez SM
Year: 2007
Journal: Brain Res
Title: Developmental expression of Kcnq4 in vestibular neurons and neurosensory epithelia.
Volume: 1139
Pages: 117-25
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Publication
22975134 | J:189014
First Author: Liang C
Year: 2012
Journal: Neurosci Lett
Title: Cell degeneration is not a primary causer for Connexin26 (GJB2) deficiency associated hearing loss.
Volume: 528
Issue: 1
Pages: 36-41
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Publication
33526661 | J:302296
 
First Author: Vong KI
Year: 2021
Journal: Proc Natl Acad Sci U S A
Title: SOX9-COL9A3-dependent regulation of choroid plexus epithelial polarity governs blood-cerebrospinal fluid barrier integrity.
Volume: 118
Issue: 6
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Publication
27603780 | J:251661
First Author: Li Z
Year: 2016
Journal: PLoS One
Title: Lgl1 Is Required for Olfaction and Development of Olfactory Bulb in Mice.
Volume: 11
Issue: 9
Pages: e0162126
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Publication
38526932 | J:348769
First Author: Hou C
Year: 2024
Journal: Neuroreport
Title: Role of LGL1 in cerebellar primordium of embryonic mice.
Volume: 35
Issue: 6
Pages: 374-379
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Publication
38896614 | J:349902
First Author: Vijayakumar S
Year: 2024
Journal: Sci Adv
Title: In silico transcriptome screens identify epidermal growth factor receptor inhibitors as therapeutics for noise-induced hearing loss.
Volume: 10
Issue: 25
Pages: eadk2299
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Publication
38498576 | J:350358
First Author: Boussaty EC
Year: 2024
Journal: PLoS Genet
Title: Altered Fhod3 expression involved in progressive high-frequency hearing loss via dysregulation of actin polymerization stoichiometry in the cuticular plate.
Volume: 20
Issue: 3
Pages: e1011211
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Publication
28115485 | J:239604
First Author: Okamoto S
Year: 2017
Journal: J Neurosci
Title: Ick Ciliary Kinase Is Essential for Planar Cell Polarity Formation in Inner Ear Hair Cells and Hearing Function.
Volume: 37
Issue: 8
Pages: 2073-2085
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Publication
35129434 | J:322946
   
First Author: Maul A
Year: 2022
Journal: Elife
Title: The Cl--channel TMEM16A is involved in the generation of cochlear Ca2+ waves and promotes the refinement of auditory brainstem networks in mice.
Volume: 11
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Publication
31909090 | J:284889
 
First Author: Choi HJ
Year: 2020
Journal: Mol Ther Methods Clin Dev
Title: DNAJC14 Ameliorates Inner Ear Degeneration in the DFNB4 Mouse Model.
Volume: 17
Pages: 188-197
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Publication
39351969 | J:357285
     
First Author: Koo HY
Year: 2024
Journal: Dev Dyn
Title: Analysis of Meis2 knockout mice reveals Sonic hedgehog-mediated patterning of the cochlear duct.
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Publication
27896618 | J:312421
First Author: Men Y
Year: 2016
Journal: Front Med
Title: Loss of liver kinase B1 causes planar polarity defects in cochlear hair cells in mice.
Volume: 10
Issue: 4
Pages: 481-489
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Publication
23716939 | J:200017
First Author: Barritt LC
Year: 2012
Journal: Indian J Hum Genet
Title: Conditional deletion of the human ortholog gene Dicer1 in Pax2-Cre expression domain impairs orofacial development.
Volume: 18
Issue: 3
Pages: 310-9
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Publication
23402760 | J:200807
First Author: Wang Z
Year: 2013
Journal: Biochem Biophys Res Commun
Title: Dissect Kif5b in nuclear positioning during myogenesis: the light chain binding domain and the autoinhibitory peptide are both indispensable.
Volume: 432
Issue: 2
Pages: 242-7
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Genotype
Genotype
Symbol: Lhx1/Lhx1 Tg(Pax2-cre)10Shwl/?
Background: involves: 129S1/Sv * 129S7/SvEvBrd * C57BL/6 * CD-1 * SJL
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tbx1/Tbx1 Tg(Pax2-cre)1Akg/?
Background: involves: 129 * C57BL/6 * SJL
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Rbpj/Rbpj Tg(Pax2-cre)1Akg/?
Background: involves: 129P2/OlaHsd
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Notch1/Notch1 Tg(Pax2-cre)1Akg/?
Background: involves: 129S1/Sv * 129X1/SvJ
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gata3/Gata3<+> Tg(Pax2-cre)1Akg/?
Background: involves: 129S4/SvJaeSor * 129S6/SvEvTac * C57BL/6Ncr
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gata3/Gata3 Tg(Pax2-cre)1Akg/?
Background: involves: 129S4/SvJaeSor * 129S6/SvEvTac * C57BL/6Ncr
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Pax2-cre)1Akg/?
Background: involves: 129 * C57BL/6 * SJL
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Hgf/Hgf Tg(Pax2-cre)1Akg/?
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CD-1
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Dicer1/Dicer1 Tg(Pax2-cre)1Akg/?
Background: involves: 129
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Chd7/Chd7 Tg(Pax2-cre)1Akg/?
Background: involves: 129S1/SvImJ * 129S6/SvEvTac * C57BL/6
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Meis2/Meis2 Tg(Pax2-cre)1Akg/?
Background: involves: 129S1/Sv * 129X1/SvJ
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Llgl1/Llgl1 Tg(Pax2-cre)1Akg/?
Background: involves: 129 * C57BL/6J
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Bdnf/Bdnf Tg(Pax2-cre)1Akg/?
Background: involves: 129S4/SvJae
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Mycn/Mycn Tg(Pax2-cre)1Akg/?
Background: involves: 129 * C57BL/6
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Fgf8/Fgf8 Tg(Pax2-cre)1Akg/?
Background: involves: 129 * C57BL/6
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Llgl1/Llgl1 Tg(Pax2-cre)1Akg/?
Background: involves: 129 * C57BL/6
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Pax2-cre)10Shwl/?
Background: involves: 129S4/SvJaeSor * C57BL/6 * SJL
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Mycn/Mycn Tg(Pax2-cre)1Akg/?
Background: involves: 129 * CD-1
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Trp63/Trp63 Tg(Pax2-cre)1Akg/?
Background: involves: 129S7/SvEvBrd * C57BL/6 * CD-1
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Trp63/Trp63<+> Tg(Pax2-cre)1Akg/?
Background: involves: 129S7/SvEvBrd * C57BL/6 * CD-1
Zygosity: cn
Has Mutant Allele: true
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