Type |
Details |
Score |
Publication |
First Author: |
Hu Z |
Year: |
2017 |
Journal: |
Cell Rep |
Title: |
CCR7 Modulates the Generation of Thymic Regulatory T Cells by Altering the Composition of the Thymic Dendritic Cell Compartment. |
Volume: |
21 |
Issue: |
1 |
Pages: |
168-180 |
|
•
•
•
•
•
|
Publication |
First Author: |
McCarthy NI |
Year: |
2015 |
Journal: |
J Immunol |
Title: |
Osteoprotegerin-Mediated Homeostasis of Rank+ Thymic Epithelial Cells Does Not Limit Foxp3+ Regulatory T Cell Development. |
Volume: |
195 |
Issue: |
6 |
Pages: |
2675-82 |
|
•
•
•
•
•
|
Publication |
First Author: |
Cowan JE |
Year: |
2018 |
Journal: |
Eur J Immunol |
Title: |
Aire controls the recirculation of murine Foxp3+ regulatory T-cells back to the thymus. |
Volume: |
48 |
Issue: |
5 |
Pages: |
844-854 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bhaumik S |
Year: |
2013 |
Journal: |
J Immunol |
Title: |
Retinoic acid hypersensitivity promotes peripheral tolerance in recent thymic emigrants. |
Volume: |
190 |
Issue: |
6 |
Pages: |
2603-13 |
|
•
•
•
•
•
|
Publication |
First Author: |
Cowan JE |
Year: |
2016 |
Journal: |
Cell Rep |
Title: |
CCR7 Controls Thymus Recirculation, but Not Production and Emigration, of Foxp3(+) T Cells. |
Volume: |
14 |
Issue: |
5 |
Pages: |
1041-1048 |
|
•
•
•
•
•
|
Publication |
First Author: |
Jimeno R |
Year: |
2019 |
Journal: |
Elife |
Title: |
Tissue-specific shaping of the TCR repertoire and antigen specificity of iNKT cells. |
Volume: |
8 |
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Cowan JE |
Year: |
2019 |
Journal: |
Nat Commun |
Title: |
Myc controls a distinct transcriptional program in fetal thymic epithelial cells that determines thymus growth. |
Volume: |
10 |
Issue: |
1 |
Pages: |
5498 |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Rag1/Rag1 Tg(LPV-TAg1135)11Tvd/? Tg(TcrLCMV)327Sdz/? |
Background: |
involves: 129S7/SvEvBrd * C57BL/6 * DBA/2 |
Zygosity: |
cx |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Rag1/Rag1<+> Tg(LPV-TAg1135)11Tvd/? Tg(TcrLCMV)327Sdz/? |
Background: |
involves: 129S7/SvEvBrd * C57BL/6 * DBA/2 |
Zygosity: |
cx |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
H2-Ab1/H2-Ab1 Rag1/Rag1 Tg(CD2-CD4,HLA-DQA1,HLA-DQB1)1Ell/Tg(CD2-CD4,HLA-DQA1,HLA-DQB1)1Ell |
Background: |
NOD.Cg-Rag1 H2-Ab1 Tg(CD2-CD4,HLA-DQA1,HLA-DQB1)1Ell |
Zygosity: |
cx |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Rag1/Rag1 Slc46a2/Slc46a2<+> Tg(TcraB12,TcrbB12)1Rest/? |
Background: |
involves: 129 * C57BL/6 |
Zygosity: |
cx |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Ins2/Ins2<+> Prf1/Prf1 Rag1/Rag1 |
Background: |
NOD.Cg-Rag1 Ins2 Prf1 |
Zygosity: |
cx |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Ins2/Ins2 Prf1/Prf1 Rag1/Rag1 |
Background: |
NOD.Cg-Rag1 Ins2 Prf1 |
Zygosity: |
cx |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Foxo1/Foxo1 Rag1/Rag1 Tg(Cd4-cre)1Cwi/? Tg(TcraTcrb)425Cbn/? |
Background: |
involves: 129S6/SvEvTac * 129S7/SvEvBrd * C57BL/6 * DBA/2 |
Zygosity: |
cn |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Foxo1/Foxo1 Rag1/Rag1 Tg(CD2-Il7r)1Asin/? Tg(Cd4-cre)1Cwi/? Tg(TcraTcrb)425Cbn/? |
Background: |
involves: 129S6/SvEvTac * 129S7/SvEvBrd * C57BL/6 * DBA/2 |
Zygosity: |
cn |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Nlrp3/Nlrp3<+> Rag1/Rag1 Lyz2/Lyz2<+> |
Background: |
involves: 129/Sv * 129P2/OlaHsd * C57BL/6 |
Zygosity: |
cn |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Gt(ROSA)26Sor/? Il5/Il5<+> Rag1/Rag1 |
Background: |
involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6 |
Zygosity: |
cn |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
H2/H2 Rag1/Rag1 Tg(HLA-DRA,HLA-DRB5*0101)hiKito/? Tg(TRATL3A6,TRBTL3A6)#Kito/? |
Background: |
involves: 129S2/SvPas * 129S7/SvEvBrd * C57BL/6 |
Zygosity: |
cx |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
H2/H2 Rag1/Rag1 Tg(HLA-DRA,HLA-DRB5*0101)loKito/? Tg(TRATL3A6,TRBTL3A6)#Kito/? |
Background: |
involves: 129S2/SvPas * 129S7/SvEvBrd * C57BL/6 |
Zygosity: |
cx |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Cmtm7/Cmtm7<+> Rag1/Rag1 |
Background: |
chimera involves: C57BL/6 * C57BL/6N |
Zygosity: |
cx |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Ctps1/Ctps1 Tg(Cd4-cre)1Cwi/? Foxp3/? Rag1/Rag1<+> |
Background: |
mixed |
Zygosity: |
cn |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Rag1/Rag1 Tg(Foxp3-EGFP/cre)1cJbs/? |
Background: |
NOD.Cg-Rag1 Tg(Foxp3-EGFP/cre)1cJbs/J |
Zygosity: |
cx |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
527
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
527
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
527
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
527
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
527
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Cunningham CA |
Year: |
2017 |
Journal: |
J Immunol |
Title: |
Cutting Edge: Defective Aerobic Glycolysis Defines the Distinct Effector Function in Antigen-Activated CD8+ Recent Thymic Emigrants. |
Volume: |
198 |
Issue: |
12 |
Pages: |
4575-4580 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bayer AL |
Year: |
2011 |
Journal: |
Eur J Immunol |
Title: |
Expansion of a restricted residual host T reg-cell repertoire is dependent on IL-2 following experimental autologous hematopoietic stem transplantation. |
Volume: |
41 |
Issue: |
12 |
Pages: |
3467-78 |
|
•
•
•
•
•
|
Publication |
First Author: |
Chen C |
Year: |
2022 |
Journal: |
Nat Commun |
Title: |
Cancer co-opts differentiation of B-cell precursors into macrophage-like cells. |
Volume: |
13 |
Issue: |
1 |
Pages: |
5376 |
|
•
•
•
•
•
|
Strain |
Attribute String: |
congenic, mutant strain, targeted mutation, transgenic |
|
•
•
•
•
•
|
Publication |
First Author: |
Tze LE |
Year: |
2005 |
Journal: |
PLoS Biol |
Title: |
Basal immunoglobulin signaling actively maintains developmental stage in immature B cells. |
Volume: |
3 |
Issue: |
3 |
Pages: |
e82 |
|
•
•
•
•
•
|
Strain |
Attribute String: |
mutant stock, targeted mutation |
|
•
•
•
•
•
|
Publication |
First Author: |
Schram BR |
Year: |
2008 |
Journal: |
J Immunol |
Title: |
B cell receptor basal signaling regulates antigen-induced Ig light chain rearrangements. |
Volume: |
180 |
Issue: |
7 |
Pages: |
4728-41 |
|
•
•
•
•
•
|
Publication |
First Author: |
Apert C |
Year: |
2022 |
Journal: |
Front Immunol |
Title: |
IL-2 and IL-15 drive intrathymic development of distinct periphery-seeding CD4+Foxp3+ regulatory T lymphocytes. |
Volume: |
13 |
|
Pages: |
965303 |
|
•
•
•
•
•
|
Publication |
First Author: |
Cunningham CA |
Year: |
2018 |
Journal: |
J Immunol |
Title: |
Cutting Edge: Glycolytic Metabolism and Mitochondrial Metabolism Are Uncoupled in Antigen-Activated CD8+ Recent Thymic Emigrants. |
Volume: |
201 |
Issue: |
6 |
Pages: |
1627-1632 |
|
•
•
•
•
•
|
Publication |
First Author: |
Higdon LE |
Year: |
2014 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Receptor revision in CD4 T cells is influenced by follicular helper T cell formation and germinal-center interactions. |
Volume: |
111 |
Issue: |
15 |
Pages: |
5652-7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Callén E |
Year: |
2007 |
Journal: |
Cell |
Title: |
ATM prevents the persistence and propagation of chromosome breaks in lymphocytes. |
Volume: |
130 |
Issue: |
1 |
Pages: |
63-75 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bréart B |
Year: |
2011 |
Journal: |
J Exp Med |
Title: |
Lipid phosphate phosphatase 3 enables efficient thymic egress. |
Volume: |
208 |
Issue: |
6 |
Pages: |
1267-78 |
|
•
•
•
•
•
|
Publication |
First Author: |
Smigiel KS |
Year: |
2014 |
Journal: |
J Exp Med |
Title: |
CCR7 provides localized access to IL-2 and defines homeostatically distinct regulatory T cell subsets. |
Volume: |
211 |
Issue: |
1 |
Pages: |
121-36 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lucas B |
Year: |
2017 |
Journal: |
Sci Rep |
Title: |
Progressive Changes in CXCR4 Expression That Define Thymocyte Positive Selection Are Dispensable For Both Innate and Conventional αβT-cell Development. |
Volume: |
7 |
Issue: |
1 |
Pages: |
5068 |
|
•
•
•
•
•
|
Publication |
First Author: |
Schallenberg S |
Year: |
2010 |
Journal: |
J Exp Med |
Title: |
Identification of an immediate Foxp3(-) precursor to Foxp3(+) regulatory T cells in peripheral lymphoid organs of nonmanipulated mice. |
Volume: |
207 |
Issue: |
7 |
Pages: |
1393-407 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wei J |
Year: |
2016 |
Journal: |
Nat Immunol |
Title: |
Autophagy enforces functional integrity of regulatory T cells by coupling environmental cues and metabolic homeostasis. |
Volume: |
17 |
Issue: |
3 |
Pages: |
277-85 |
|
•
•
•
•
•
|
Publication |
First Author: |
Martins VC |
Year: |
2014 |
Journal: |
Nature |
Title: |
Cell competition is a tumour suppressor mechanism in the thymus. |
Volume: |
509 |
Issue: |
7501 |
Pages: |
465-70 |
|
•
•
•
•
•
|
Publication |
First Author: |
Houston EG Jr |
Year: |
2011 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Recent thymic emigrants are preferentially incorporated only into the depleted T-cell pool. |
Volume: |
108 |
Issue: |
13 |
Pages: |
5366-71 |
|
•
•
•
•
•
|
Publication |
First Author: |
Breed ER |
Year: |
2019 |
Journal: |
J Immunol |
Title: |
Measuring Thymic Clonal Deletion at the Population Level. |
Volume: |
202 |
Issue: |
11 |
Pages: |
3226-3233 |
|
•
•
•
•
•
|
Publication |
First Author: |
Li Y |
Year: |
2023 |
Journal: |
Elife |
Title: |
CCR4 and CCR7 differentially regulate thymocyte localization with distinct outcomes for central tolerance. |
Volume: |
12 |
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Watanabe M |
Year: |
2022 |
Journal: |
Cell Rep |
Title: |
Antigen-presenting T cells provide critical B7 co-stimulation for thymic iNKT cell development via CD28-dependent trogocytosis. |
Volume: |
41 |
Issue: |
9 |
Pages: |
111731 |
|
•
•
•
•
•
|
Publication |
First Author: |
Pierson W |
Year: |
2013 |
Journal: |
Nat Immunol |
Title: |
Antiapoptotic Mcl-1 is critical for the survival and niche-filling capacity of Foxp3⁺ regulatory T cells. |
Volume: |
14 |
Issue: |
9 |
Pages: |
959-65 |
|
•
•
•
•
•
|
Publication |
First Author: |
Watanabe M |
Year: |
2020 |
Journal: |
Nat Commun |
Title: |
B7-CD28 co-stimulation modulates central tolerance via thymic clonal deletion and Treg generation through distinct mechanisms. |
Volume: |
11 |
Issue: |
1 |
Pages: |
6264 |
|
•
•
•
•
•
|