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Search results 3101 to 3200 out of 3295 for Kras

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Type Details Score
Publication
33397922 | J:300957
First Author: Pickering KA
Year: 2021
Journal: Nat Commun
Title: A RAC-GEF network critical for early intestinal tumourigenesis.
Volume: 12
Issue: 1
Pages: 56
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33610731 | J:303946
 
First Author: Munagala R
Year: 2021
Journal: Cancer Lett
Title: Exosome-mediated delivery of RNA and DNA for gene therapy.
Volume: 505
Pages: 58-72
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Publication
33589425 | J:307163
     
First Author: Pitarresi JR
Year: 2021
Journal: Cancer Discov
Title: PTHrP drives pancreatic cancer growth and metastasis and reveals a new therapeutic vulnerability.
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Publication
29340023 | J:309222
First Author: Mao Y
Year: 2017
Journal: Oncotarget
Title: Role and regulation of Yap in KrasG12D-induced lung cancer.
Volume: 8
Issue: 67
Pages: 110877-110889
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Publication
34380736 | J:309468
 
First Author: Castel P
Year: 2021
Journal: Proc Natl Acad Sci U S A
Title: RAS interaction with Sin1 is dispensable for mTORC2 assembly and activity.
Volume: 118
Issue: 33
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Publication
32589309 | J:326402
First Author: Zhong C
Year: 2020
Journal: Cancer Sci
Title: ZNF251 promotes the progression of lung cancer by activating ERK signaling.
Volume: 111
Issue: 9
Pages: 3236-3244
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24982195 | J:320715
First Author: Sinkevicius KW
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Neurotrophin receptor TrkB promotes lung adenocarcinoma metastasis.
Volume: 111
Issue: 28
Pages: 10299-304
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Publication
35139374 | J:327104
First Author: Venkatanarayan A
Year: 2022
Journal: Cell Rep
Title: CRAF dimerization with ARAF regulates KRAS-driven tumor growth.
Volume: 38
Issue: 6
Pages: 110351
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Publication
35562376 | J:324554
First Author: Liu Y
Year: 2022
Journal: Nat Commun
Title: Rapid acceleration of KRAS-mutant pancreatic carcinogenesis via remodeling of tumor immune microenvironment by PPARδ.
Volume: 13
Issue: 1
Pages: 2665
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Publication
35589755 | J:324987
First Author: Hall AE
Year: 2022
Journal: Nat Commun
Title: RNA splicing is a key mediator of tumour cell plasticity and a therapeutic vulnerability in colorectal cancer.
Volume: 13
Issue: 1
Pages: 2791
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Publication
35262628 | J:329458
 
First Author: Jiang H
Year: 2022
Journal: J Exp Med
Title: Ferrous iron-activatable drug conjugate achieves potent MAPK blockade in KRAS-driven tumors.
Volume: 219
Issue: 4
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Publication
36810256 | J:333757
 
First Author: Xie Y
Year: 2023
Journal: JCI Insight
Title: SETD2 regulates chromatin accessibility and transcription to suppress lung tumorigenesis.
Volume: 8
Issue: 4
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Publication
37845485 | J:344824
First Author: Feng Z
Year: 2024
Journal: Nat Cancer
Title: An in vitro-transcribed circular RNA targets the mitochondrial inner membrane cardiolipin to ablate EIF4G2(+)/PTBP1(+) pan-adenocarcinoma.
Volume: 5
Issue: 1
Pages: 30-46
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Publication
38605037 | J:347359
First Author: Fu J
Year: 2024
Journal: Nat Commun
Title: Nardilysin-regulated scission mechanism activates polo-like kinase 3 to suppress the development of pancreatic cancer.
Volume: 15
Issue: 1
Pages: 3149
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Publication
18178811 | J:130950
First Author: Janas ML
Year: 2008
Journal: J Immunol
Title: The effect of deleting p110delta on the phenotype and function of PTEN-deficient B cells.
Volume: 180
Issue: 2
Pages: 739-46
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Publication
26809587 | J:230653
 
First Author: Grego-Bessa J
Year: 2016
Journal: Elife
Title: The tumor suppressor PTEN and the PDK1 kinase regulate formation of the columnar neural epithelium.
Volume: 5
Pages: e12034
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Publication
19076778 | J:173443
First Author: Huse JT
Year: 2009
Journal: Brain Pathol
Title: Genetically engineered mouse models of brain cancer and the promise of preclinical testing.
Volume: 19
Issue: 1
Pages: 132-43
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Publication
30484104 | J:307676
First Author: Hollern DP
Year: 2019
Journal: Breast Cancer Res Treat
Title: A mouse model featuring tissue-specific deletion of p53 and Brca1 gives rise to mammary tumors with genomic and transcriptomic similarities to human basal-like breast cancer.
Volume: 174
Issue: 1
Pages: 143-155
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34521767 | J:311175
 
First Author: Andrijes R
Year: 2021
Journal: Proc Natl Acad Sci U S A
Title: Tetraspanin 6 is a regulator of carcinogenesis in colorectal cancer.
Volume: 118
Issue: 39
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Publication
32567731 | J:301694
First Author: Raposo TP
Year: 2020
Journal: Int J Exp Pathol
Title: Tensin4 (TNS4) is upregulated by Wnt signalling in adenomas in multiple intestinal neoplasia (Min) mice.
Volume: 101
Issue: 3-4
Pages: 80-86
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31237864 | J:297143
   
First Author: Gbenedio OM
Year: 2019
Journal: JCI Insight
Title: RasGRP1 is a potential biomarker to stratify anti-EGFR therapy response in colorectal cancer.
Volume: 5
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19690388 | J:152703
First Author: Lee D
Year: 2009
Journal: J Clin Invest
Title: Tumor-specific apoptosis caused by deletion of the ERBB3 pseudo-kinase in mouse intestinal epithelium.
Volume: 119
Issue: 9
Pages: 2702-13
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Publication
16397217 | J:105038
First Author: Reilly KM
Year: 2006
Journal: Cancer Res
Title: An imprinted locus epistatically influences Nstr1 and Nstr2 to control resistance to nerve sheath tumors in a neurofibromatosis type 1 mouse model.
Volume: 66
Issue: 1
Pages: 62-8
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18472967 | J:138670
First Author: Lyustikman Y
Year: 2008
Journal: Neoplasia
Title: Constitutive activation of Raf-1 induces glioma formation in mice.
Volume: 10
Issue: 5
Pages: 501-10
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17575131 | J:122413
First Author: Yang G
Year: 2007
Journal: Cancer Res
Title: Loss of xeroderma pigmentosum C (Xpc) enhances melanoma photocarcinogenesis in Ink4a-Arf-deficient mice.
Volume: 67
Issue: 12
Pages: 5649-57
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21949886 | J:177670
First Author: Põlajeva J
Year: 2011
Journal: PLoS One
Title: Mast cell accumulation in glioblastoma with a potential role for stem cell factor and chemokine CXCL12.
Volume: 6
Issue: 9
Pages: e25222
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17200209 | J:117211
First Author: Alberici P
Year: 2007
Journal: Am J Pathol
Title: Aneuploidy arises at early stages of Apc-driven intestinal tumorigenesis and pinpoints conserved chromosomal loci of allelic imbalance between mouse and human.
Volume: 170
Issue: 1
Pages: 377-87
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Publication
17251932 | J:118233
First Author: Ventura A
Year: 2007
Journal: Nature
Title: Restoration of p53 function leads to tumour regression in vivo.
Volume: 445
Issue: 7128
Pages: 661-5
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23752194 | J:212363
First Author: Busch SE
Year: 2014
Journal: Oncogene
Title: ARF inhibits the growth and malignant progression of non-small-cell lung carcinoma.
Volume: 33
Issue: 20
Pages: 2665-73
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24875860 | J:217843
First Author: Yang A
Year: 2014
Journal: Cancer Discov
Title: Autophagy is critical for pancreatic tumor growth and progression in tumors with p53 alterations.
Volume: 4
Issue: 8
Pages: 905-13
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23603816 | J:198505
First Author: Jameson KL
Year: 2013
Journal: Nat Med
Title: IQGAP1 scaffold-kinase interaction blockade selectively targets RAS-MAP kinase-driven tumors.
Volume: 19
Issue: 5
Pages: 626-630
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29443959 | J:261800
First Author: Cobo I
Year: 2018
Journal: Nature
Title: Transcriptional regulation by NR5A2 links differentiation and inflammation in the pancreas.
Volume: 554
Issue: 7693
Pages: 533-537
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35074757 | J:324032
First Author: Younger NT
Year: 2022
Journal: Cancer Res
Title: In Vivo Modeling of Patient Genetic Heterogeneity Identifies New Ways to Target Cholangiocarcinoma.
Volume: 82
Issue: 8
Pages: 1548-1559
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Publication
28835438 | J:246313
First Author: Dovey OM
Year: 2017
Journal: Blood
Title: Molecular synergy underlies the co-occurrence patterns and phenotype of NPM1-mutant acute myeloid leukemia.
Volume: 130
Issue: 17
Pages: 1911-1922
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Publication
24240680 | J:216269
First Author: Chen X
Year: 2014
Journal: Oncogene
Title: Transformation by Hras(G12V) is consistently associated with mutant allele copy gains and is reversed by farnesyl transferase inhibition.
Volume: 33
Issue: 47
Pages: 5442-9
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Publication
28255028 | J:263735
First Author: Guo M
Year: 2017
Journal: EMBO Mol Med
Title: Gene signature driving invasive mucinous adenocarcinoma of the lung.
Volume: 9
Issue: 4
Pages: 462-481
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Publication
28851812 | J:249479
First Author: Yochum ZA
Year: 2017
Journal: Mol Cancer Res
Title: A First-in-Class TWIST1 Inhibitor with Activity in Oncogene-Driven Lung Cancer.
Volume: 15
Issue: 12
Pages: 1764-1776
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Publication
38958646 | J:354671
First Author: Donahue KL
Year: 2024
Journal: Cancer Discov
Title: Oncogenic KRAS-Dependent Stromal Interleukin-33 Directs the Pancreatic Microenvironment to Promote Tumor Growth.
Volume: 14
Issue: 10
Pages: 1964-1989
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Publication
24618618 | J:211558
First Author: Schuster K
Year: 2014
Journal: Mol Cancer Res
Title: Nullifying the CDKN2AB locus promotes mutant K-ras lung tumorigenesis.
Volume: 12
Issue: 6
Pages: 912-23
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Publication
27911940 | J:250854
First Author: Weyandt JD
Year: 2016
Journal: PLoS One
Title: Isoform-Specific Effects of Wild-Type Ras Genes on Carcinogen-Induced Lung Tumorigenesis in Mice.
Volume: 11
Issue: 12
Pages: e0167205
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Publication
35561328 | J:327828
First Author: Satoh H
Year: 2022
Journal: Carcinogenesis
Title: Genomic landscape of chemical-induced lung tumors under Nrf2 different expression levels.
Volume: 43
Issue: 7
Pages: 613-623
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Publication
38963974 | J:352030
 
First Author: Witherspoon JG
Year: 2024
Journal: Redox Biol
Title: Mutant Nrf2(E79Q) enhances the promotion and progression of a subset of oncogenic Ras keratinocytes and skin tumors.
Volume: 75
Pages: 103261
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Publication
25870145 | J:222565
First Author: Eberlein CA
Year: 2015
Journal: Cancer Res
Title: Acquired Resistance to the Mutant-Selective EGFR Inhibitor AZD9291 Is Associated with Increased Dependence on RAS Signaling in Preclinical Models.
Volume: 75
Issue: 12
Pages: 2489-500
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Publication
21406400 | J:169920
First Author: Allen TD
Year: 2011
Journal: Cancer Res
Title: Interaction between MYC and MCL1 in the genesis and outcome of non-small-cell lung cancer.
Volume: 71
Issue: 6
Pages: 2212-21
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Publication
18635814 | J:155786
First Author: Minowada G
Year: 2009
Journal: Am J Respir Cell Mol Biol
Title: Overexpression of Sprouty 2 in mouse lung epithelium inhibits urethane-induced tumorigenesis.
Volume: 40
Issue: 1
Pages: 31-7
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Publication
29382756 | J:259854
First Author: Tan Q
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: Loss of Capicua alters early T cell development and predisposes mice to T cell lymphoblastic leukemia/lymphoma.
Volume: 115
Issue: 7
Pages: E1511-E1519
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Publication
17217625 | J:121511
First Author: Shih AH
Year: 2006
Journal: Neoplasia
Title: Notch signaling enhances nestin expression in gliomas.
Volume: 8
Issue: 12
Pages: 1072-82
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Publication
24386508 | J:204127
First Author: Robinson GL
Year: 2013
Journal: Genes Cancer
Title: Akt signaling accelerates tumor recurrence following ras inhibition in the context of ink4a/arf loss.
Volume: 4
Issue: 11-12
Pages: 476-85
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Publication
27991934 | J:243158
First Author: Pomeroy EJ
Year: 2017
Journal: Oncogene
Title: Ras oncogene-independent activation of RALB signaling is a targetable mechanism of escape from NRAS(V12) oncogene addiction in acute myeloid leukemia.
Volume: 36
Issue: 23
Pages: 3263-3273
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Publication
16210915 | J:104191
First Author: Kirley SD
Year: 2005
Journal: Cancer Biol Ther
Title: The Cables gene on chromosome 18Q regulates colon cancer progression in vivo.
Volume: 4
Issue: 8
Pages: 861-3
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Publication
25170306 | J:302635
First Author: Isoda T
Year: 2014
Journal: Int J Biol Sci
Title: Abnormality in Wnt signaling is causatively associated with oxidative stress-induced intestinal tumorigenesis in MUTYH-null mice.
Volume: 10
Issue: 8
Pages: 940-7
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Publication
24825889 | J:211270
First Author: Wiener Z
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Oncogenic mutations in intestinal adenomas regulate Bim-mediated apoptosis induced by TGF-β.
Volume: 111
Issue: 21
Pages: E2229-36
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Publication
37883185 | J:349262
 
First Author: Danan CH
Year: 2023
Journal: JCI Insight
Title: Intestinal transit-amplifying cells require METTL3 for growth factor signaling and cell survival.
Volume: 8
Issue: 23
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Publication
26979394 | J:316573
First Author: Dibra D
Year: 2016
Journal: Clin Cancer Res
Title: Lack of Immunomodulatory Interleukin-27 Enhances Oncogenic Properties of Mutant p53 In Vivo.
Volume: 22
Issue: 15
Pages: 3876-83
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Publication
24567410 | J:328676
First Author: Hoshii T
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Loss of mTOR complex 1 induces developmental blockage in early T-lymphopoiesis and eradicates T-cell acute lymphoblastic leukemia cells.
Volume: 111
Issue: 10
Pages: 3805-10
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Publication
38418883 | J:349910
First Author: Han G
Year: 2024
Journal: Nature
Title: An atlas of epithelial cell states and plasticity in lung adenocarcinoma.
Volume: 627
Issue: 8004
Pages: 656-663
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Publication
28639695 | J:246658
First Author: Ding L
Year: 2017
Journal: J Pathol
Title: Glycogen synthase kinase-3β ablation limits pancreatitis-induced acinar-to-ductal metaplasia.
Volume: 243
Issue: 1
Pages: 65-77
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Publication
20959479 | J:165773
First Author: Jorgenson TC
Year: 2010
Journal: Cancer Res
Title: Identification of susceptibility loci in a mouse model of KRASG12D-driven pancreatic cancer.
Volume: 70
Issue: 21
Pages: 8398-406
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Publication
24894865 | J:213494
First Author: Zeineldin M
Year: 2014
Journal: Carcinogenesis
Title: Nuclear adenomatous polyposis coli suppresses colitis-associated tumorigenesis in mice.
Volume: 35
Issue: 8
Pages: 1881-90
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Publication
24850902 | J:216024
First Author: Mehner C
Year: 2014
Journal: Mol Cancer Res
Title: Tumor cell-derived MMP3 orchestrates Rac1b and tissue alterations that promote pancreatic adenocarcinoma.
Volume: 12
Issue: 10
Pages: 1430-9
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Publication
32047266 | J:299543
First Author: Richter AM
Year: 2020
Journal: Oncogene
Title: RASSF10 is frequently epigenetically inactivated in kidney cancer and its knockout promotes neoplasia in cancer prone mice.
Volume: 39
Issue: 15
Pages: 3114-3127
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Publication
38992029 | J:354130
First Author: Zhou X
Year: 2024
Journal: Nat Commun
Title: Inhibition of DUSP18 impairs cholesterol biosynthesis and promotes anti-tumor immunity in colorectal cancer.
Volume: 15
Issue: 1
Pages: 5851
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Publication
16618742 | J:108306
First Author: Wislez M
Year: 2006
Journal: Cancer Res
Title: High expression of ligands for chemokine receptor CXCR2 in alveolar epithelial neoplasia induced by oncogenic kras.
Volume: 66
Issue: 8
Pages: 4198-207
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Publication
15790496 | J:97087
First Author: Kakinuma S
Year: 2005
Journal: Mutat Res
Title: Frequent retention of heterozygosity for point mutations in p53 and Ikaros in N-ethyl-N-nitrosourea-induced mouse thymic lymphomas.
Volume: 572
Issue: 1-2
Pages: 132-41
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Publication
17520196 | J:123974
First Author: Feldmann G
Year: 2007
Journal: J Hepatobiliary Pancreat Surg
Title: Molecular genetics of pancreatic intraepithelial neoplasia.
Volume: 14
Issue: 3
Pages: 224-32
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Publication
18089788 | J:130799
First Author: Uronis JM
Year: 2007
Journal: Cancer Res
Title: Flat colorectal cancers are genetically determined and progress to invasion without going through a polypoid stage.
Volume: 67
Issue: 24
Pages: 11594-600
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19880654 | J:156960
First Author: Fan HY
Year: 2010
Journal: Mol Endocrinol
Title: Minireview: physiological and pathological actions of RAS in the ovary.
Volume: 24
Issue: 2
Pages: 286-98
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22684892 | J:191774
First Author: Hirano S
Year: 2013
Journal: Int J Cancer
Title: Ikaros is a critical target during simultaneous exposure to X-rays and N-ethyl-N-nitrosourea in mouse T-cell lymphomagenesis.
Volume: 132
Issue: 2
Pages: 259-68
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Publication
39111635 | J:354205
First Author: Saeki K
Year: 2024
Journal: Cell Mol Gastroenterol Hepatol
Title: Acvr1b Loss Increases Formation of Pancreatic Precancerous Lesions From Acinar and Ductal Cells of Origin.
Volume: 18
Issue: 5
Pages: 101387
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Publication
23539443 | J:197044
First Author: Lau T
Year: 2013
Journal: Cancer Res
Title: A novel tankyrase small-molecule inhibitor suppresses APC mutation-driven colorectal tumor growth.
Volume: 73
Issue: 10
Pages: 3132-44
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Publication
23929436 | J:202770
First Author: Fahrer J
Year: 2013
Journal: Carcinogenesis
Title: O6-methylguanine-DNA methyltransferase in the defense against N-nitroso compounds and colorectal cancer.
Volume: 34
Issue: 11
Pages: 2435-42
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Publication
24374827 | J:209058
First Author: Gastaldi C
Year: 2014
Journal: Carcinogenesis
Title: miR-193b/365a cluster controls progression of epidermal squamous cell carcinoma.
Volume: 35
Issue: 5
Pages: 1110-20
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Publication
24670819 | J:210813
First Author: Lin WC
Year: 2014
Journal: Cancer Res
Title: Cancer cell dormancy in novel mouse models for reversible pancreatic cancer: a lingering challenge in the development of targeted therapies.
Volume: 74
Issue: 8
Pages: 2138-43
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Publication
24743516 | J:212557
First Author: Sousa CM
Year: 2014
Journal: Carcinogenesis
Title: The complex landscape of pancreatic cancer metabolism.
Volume: 35
Issue: 7
Pages: 1441-50
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Publication
25197077 | J:216493
First Author: Satow R
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Phospholipase Cδ1 induces E-cadherin expression and suppresses malignancy in colorectal cancer cells.
Volume: 111
Issue: 37
Pages: 13505-10
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Publication
25736685 | J:219941
First Author: Pettazzoni P
Year: 2015
Journal: Cancer Res
Title: Genetic events that limit the efficacy of MEK and RTK inhibitor therapies in a mouse model of KRAS-driven pancreatic cancer.
Volume: 75
Issue: 6
Pages: 1091-101
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Publication
25632159 | J:223840
First Author: Deng W
Year: 2015
Journal: J Cell Sci
Title: SOX9 inhibits β-TrCP-mediated protein degradation to promote nuclear GLI1 expression and cancer stem cell properties.
Volume: 128
Issue: 6
Pages: 1123-38
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Publication
26113087 | J:225595
First Author: Sawai Y
Year: 2015
Journal: Cancer Res
Title: Activation-Induced Cytidine Deaminase Contributes to Pancreatic Tumorigenesis by Inducing Tumor-Related Gene Mutations.
Volume: 75
Issue: 16
Pages: 3292-301
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Publication
25706875 | J:227933
First Author: Matano M
Year: 2015
Journal: Nat Med
Title: Modeling colorectal cancer using CRISPR-Cas9-mediated engineering of human intestinal organoids.
Volume: 21
Issue: 3
Pages: 256-62
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Publication
26715643 | J:236131
First Author: Pylayeva-Gupta Y
Year: 2016
Journal: Cancer Discov
Title: IL35-Producing B Cells Promote the Development of Pancreatic Neoplasia.
Volume: 6
Issue: 3
Pages: 247-55
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Publication
26833127 | J:236574
First Author: Koyama S
Year: 2016
Journal: Cancer Res
Title: STK11/LKB1 Deficiency Promotes Neutrophil Recruitment and Proinflammatory Cytokine Production to Suppress T-cell Activity in the Lung Tumor Microenvironment.
Volume: 76
Issue: 5
Pages: 999-1008
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Publication
28096419 | J:240741
First Author: Sherman MH
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: Stromal cues regulate the pancreatic cancer epigenome and metabolome.
Volume: 114
Issue: 5
Pages: 1129-1134
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Publication
27864140 | J:255651
First Author: Mirra P
Year: 2017
Journal: Biochim Biophys Acta
Title: The role of miR-190a in methylglyoxal-induced insulin resistance in endothelial cells.
Volume: 1863
Issue: 2
Pages: 440-449
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Publication
29367758 | J:261040
First Author: Szczepny A
Year: 2018
Journal: Oncogene
Title: The tumor suppressor Hic1 maintains chromosomal stability independent of Tp53.
Volume: 37
Issue: 14
Pages: 1939-1948
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Publication
30355676 | J:271157
First Author: Rahrmann EP
Year: 2019
Journal: Mol Cancer Res
Title: Sleeping Beauty Screen Identifies RREB1 and Other Genetic Drivers in Human B-cell Lymphoma.
Volume: 17
Issue: 2
Pages: 567-582
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Publication
31088909 | J:277618
First Author: Sippel TR
Year: 2019
Journal: Mol Cancer Res
Title: Activation of PPARγ in Myeloid Cells Promotes Progression of Epithelial Lung Tumors through TGFβ1.
Volume: 17
Issue: 8
Pages: 1748-1758
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