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Search results 3101 to 3175 out of 3175 for Mapt

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Type Details Score
Publication
31467276 | J:279320
First Author: Jadiya P
Year: 2019
Journal: Nat Commun
Title: Impaired mitochondrial calcium efflux contributes to disease progression in models of Alzheimer's disease.
Volume: 10
Issue: 1
Pages: 3885
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Publication
40373772 | J:369611
First Author: Liu J
Year: 2025
Journal: Immunity
Title: Microglial TMEM119 binds to amyloid-? to promote its clearance in an A?-depositing mouse model of Alzheimer's disease.
Volume: 58
Issue: 7
Pages: 1830-1846.e7
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Publication
27210751 | J:235961
First Author: Hamilton A
Year: 2016
Journal: Cell Rep
Title: Chronic Pharmacological mGluR5 Inhibition Prevents Cognitive Impairment and Reduces Pathogenesis in an Alzheimer Disease Mouse Model.
Volume: 15
Issue: 9
Pages: 1859-65
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Publication
32849642 | J:319606
 
First Author: Zhao J
Year: 2020
Journal: Front Immunol
Title: Administration of Amyloid Precursor Protein Gene Deleted Mouse ESC-Derived Thymic Epithelial Progenitors Attenuates Alzheimer's Pathology.
Volume: 11
Pages: 1781
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Publication
24684630 | J:214689
First Author: Kuwabara Y
Year: 2014
Journal: J Neurochem
Title: Impairments of long-term depression induction and motor coordination precede A? accumulation in the cerebellum of APPswe/PS1dE9 double transgenic mice.
Volume: 130
Issue: 3
Pages: 432-43
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Publication
28683325 | J:254503
First Author: Haas LT
Year: 2017
Journal: Cell Rep
Title: Silent Allosteric Modulation of mGluR5 Maintains Glutamate Signaling while Rescuing Alzheimer's Mouse Phenotypes.
Volume: 20
Issue: 1
Pages: 76-88
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Publication
30050035 | J:264863
First Author: Wei Y
Year: 2018
Journal: Cell Death Dis
Title: Oxidation of KCNB1 channels in the human brain and in mouse model of Alzheimer's disease.
Volume: 9
Issue: 8
Pages: 820
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Publication
41488470 | J:385505
First Author: Cho Y
Year: 2026
Journal: MedComm (2020)
Title: Ramalin Ameliorates Alzheimer's Disease Pathology by Targeting BACE1, HDAC6, and MAPK Pathways.
Volume: 7
Issue: 1
Pages: e70518
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Publication
32098978 | J:293886
First Author: Jiang H
Year: 2020
Journal: Sci Rep
Title: Live Neuron High-Content Screening Reveals Synaptotoxic Activity in Alzheimer Mouse Model Homogenates.
Volume: 10
Issue: 1
Pages: 3412
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Publication
33791294 | J:318609
 
First Author: Huang X
Year: 2021
Journal: Front Cell Dev Biol
Title: Tetramethylpyrazine Improves Cognitive Impairment and Modifies the Hippocampal Proteome in Two Mouse Models of Alzheimer's Disease.
Volume: 9
Pages: 632843
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Publication
23534431 | J:352629
First Author: Stargardt A
Year: 2013
Journal: Aging Cell
Title: Reduced amyloid-? degradation in early Alzheimer's disease but not in the APPswePS1dE9 and 3xTg-AD mouse models.
Volume: 12
Issue: 3
Pages: 499-507
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Publication
33672482 | J:352640
 
First Author: Drews HJ
Year: 2021
Journal: Pharmaceuticals (Basel)
Title: Losartan Improves Memory, Neurogenesis and Cell Motility in Transgenic Alzheimer's Mice.
Volume: 14
Issue: 2
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Publication
35961653 | J:352637
First Author: Israel LL
Year: 2022
Journal: ACS Nano
Title: Signature Effects of Vector-Guided Systemic Nano Bioconjugate Delivery Across Blood-Brain Barrier of Normal, Alzheimer's, and Tumor Mouse Models.
Volume: 16
Issue: 8
Pages: 11815-11832
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Publication
35775150 | J:349319
First Author: Vande Vyver M
Year: 2022
Journal: Epilepsia
Title: Higher susceptibility to 6?Hz corneal kindling and lower responsiveness to antiseizure drugs in mouse models of Alzheimer's disease.
Volume: 63
Issue: 10
Pages: 2703-2715
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Publication
33863723 | J:358337
 
First Author: Chen G
Year: 2021
Journal: Sci Adv
Title: Netrin-1 receptor UNC5C cleavage by active ?-secretase enhances neurodegeneration, promoting Alzheimer's disease pathologies.
Volume: 7
Issue: 16
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Publication
37358017 | J:339350
First Author: Marinho D
Year: 2023
Journal: Aging Cell
Title: Reduction of class I histone deacetylases ameliorates ER-mitochondria cross-talk in Alzheimer's disease.
Volume: 22
Issue: 8
Pages: e13895
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Publication
33345400 | J:352826
First Author: Jang YN
Year: 2021
Journal: Neuropathol Appl Neurobiol
Title: RAPGEF2 mediates oligomeric A?-induced synaptic loss and cognitive dysfunction in the 3xTg-AD mouse model of Alzheimer's disease.
Volume: 47
Issue: 5
Pages: 625-639
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Publication
26280122 | J:228804
First Author: Ceglia I
Year: 2015
Journal: Nat Med
Title: APP intracellular domain-WAVE1 pathway reduces amyloid-? production.
Volume: 21
Issue: 9
Pages: 1054-9
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Publication
31737743 | J:352853
First Author: Wang S
Year: 2019
Journal: Neurophotonics
Title: Label-free multiphoton imaging of ?-amyloid plaques in Alzheimer's disease mouse models.
Volume: 6
Issue: 4
Pages: 045008
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Publication
41480410 | J:385742
First Author: Tang S
Year: 2026
Journal: Genes Dis
Title: Hippocampus-targeted BDNF gene therapy to rescue cognitive impairments of Alzheimer's disease in multiple mouse models.
Volume: 13
Issue: 2
Pages: 101649
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Publication
27425620 | J:238659
First Author: Liebmann T
Year: 2016
Journal: Cell Rep
Title: Three-Dimensional Study of Alzheimer's Disease Hallmarks Using the iDISCO Clearing Method.
Volume: 16
Issue: 4
Pages: 1138-1152
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Publication
32404941 | J:348427
First Author: Song G
Year: 2020
Journal: Sci Rep
Title: Multimodal Coherent Imaging of Retinal Biomarkers of Alzheimer's Disease in a Mouse Model.
Volume: 10
Issue: 1
Pages: 7912
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Publication
22912745 | J:189978
First Author: Kamphuis W
Year: 2012
Journal: PLoS One
Title: GFAP isoforms in adult mouse brain with a focus on neurogenic astrocytes and reactive astrogliosis in mouse models of Alzheimer disease.
Volume: 7
Issue: 8
Pages: e42823
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Publication
25617315 | J:232678
First Author: Clarke JR
Year: 2015
Journal: EMBO Mol Med
Title: Alzheimer-associated A? oligomers impact the central nervous system to induce peripheral metabolic deregulation.
Volume: 7
Issue: 2
Pages: 190-210
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Publication
30322407 | J:368485
First Author: Ceyz?riat K
Year: 2018
Journal: Acta Neuropathol Commun
Title: Modulation of astrocyte reactivity improves functional deficits in mouse models of Alzheimer's disease.
Volume: 6
Issue: 1
Pages: 104
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Publication
21980472 | J:368227
First Author: Tran HT
Year: 2011
Journal: PLoS One
Title: Distinct temporal and anatomical distributions of amyloid-? and tau abnormalities following controlled cortical impact in transgenic mice.
Volume: 6
Issue: 9
Pages: e25475
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Publication
26982728 | J:232713
First Author: Roy DS
Year: 2016
Journal: Nature
Title: Memory retrieval by activating engram cells in mouse models of early Alzheimer's disease.
Volume: 531
Issue: 7595
Pages: 508-12
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Publication
38306030 | J:368266
First Author: Ng PY
Year: 2024
Journal: J Alzheimers Dis
Title: Senescence Targeting Methods Impact Alzheimer's Disease Features in 3xTg Mice.
Volume: 97
Issue: 4
Pages: 1751-1763
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Publication
23432034 | J:199628
First Author: Chakravarthy B
Year: 2013
Journal: J Neurochem
Title: A synthetic peptide corresponding to a region of the human pericentriolar material 1 (PCM-1) protein binds ?-amyloid (A?1-42 ) oligomers.
Volume: 126
Issue: 3
Pages: 415-24
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Publication
29211722 | J:274288
First Author: Sorrentino V
Year: 2017
Journal: Nature
Title: Enhancing mitochondrial proteostasis reduces amyloid-? proteotoxicity.
Volume: 552
Issue: 7684
Pages: 187-193
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Publication
39510074 | J:368337
First Author: Zha X
Year: 2025
Journal: Cell Metab
Title: Microbiota-derived lysophosphatidylcholine alleviates Alzheimer's disease pathology via suppressing ferroptosis.
Volume: 37
Issue: 1
Pages: 169-186.e9
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Publication
37402372 | J:340719
First Author: Wu Y
Year: 2023
Journal: Neuron
Title: Hepatic soluble epoxide hydrolase activity regulates cerebral A? metabolism and the pathogenesis of Alzheimer's disease in mice.
Volume: 111
Issue: 18
Pages: 2847-2862.e10
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Publication
41935184 | J:386834
     
First Author: Lei Y
Year: 2026
Journal: Mol Psychiatry
Title: Neuronal HDAC9: A key regulator of cognitive and synaptic aging, rescuing Alzheimer's disease-related phenotypes.
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Publication
40273909 | J:368620
First Author: Chen J
Year: 2025
Journal: Cell
Title: Transcriptional regulation by PHGDH drives amyloid pathology in Alzheimer's disease.
Volume: 188
Issue: 13
Pages: 3513-3529.e26
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Publication
29298895 | J:262527
First Author: Hashimoto S
Year: 2018
Journal: J Biol Chem
Title: Endoplasmic reticulum stress responses in mouse models of Alzheimer's disease: Overexpression paradigm versus knockin paradigm.
Volume: 293
Issue: 9
Pages: 3118-3125
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Publication
33922642 | J:386849
 
First Author: Delgado-Peraza F
Year: 2021
Journal: Cells
Title: Neuronal and Astrocytic Extracellular Vesicle Biomarkers in Blood Reflect Brain Pathology in Mouse Models of Alzheimer's Disease.
Volume: 10
Issue: 5
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Publication
35236988 | J:338102
First Author: Xiong J
Year: 2022
Journal: Nature
Title: FSH blockade improves cognition in mice with Alzheimer's disease.
Volume: 603
Issue: 7901
Pages: 470-476
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Publication
25673868 | J:219873
First Author: Ben Haim L
Year: 2015
Journal: J Neurosci
Title: The JAK/STAT3 pathway is a common inducer of astrocyte reactivity in Alzheimer's and Huntington's diseases.
Volume: 35
Issue: 6
Pages: 2817-29
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Publication
27425031 | J:255474
First Author: Kamphuis W
Year: 2016
Journal: Biochim Biophys Acta
Title: Transcriptional profiling of CD11c-positive microglia accumulating around amyloid plaques in a mouse model for Alzheimer's disease.
Volume: 1862
Issue: 10
Pages: 1847-60
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Publication
38476461 | J:346241
 
First Author: Devadoss D
Year: 2024
Journal: Front Mol Neurosci
Title: LRRC25 expression during physiological aging and in mouse models of Alzheimer's disease and iPSC-derived neurons.
Volume: 17
Pages: 1365752
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Publication
29393544 | J:258731
First Author: Valny M
Year: 2018
Journal: Glia
Title: A single-cell analysis reveals multiple roles of oligodendroglial lineage cells during post-ischemic regeneration.
Volume: 66
Issue: 5
Pages: 1068-1081
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Publication
30742114 | J:277544
First Author: Fang EF
Year: 2019
Journal: Nat Neurosci
Title: Mitophagy inhibits amyloid-? and tau pathology and reverses cognitive deficits in models of Alzheimer's disease.
Volume: 22
Issue: 3
Pages: 401-412
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Publication
42180652 | J:388165
 
First Author: Sauv?? F
Year: 2026
Journal: Cell Press Blue
Title: Tanycytic degeneration impairs tau clearance and contributes to Alzheimer's disease pathology.
Volume: 1
Issue: 1
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Publication
41061696 | J:377422
First Author: Mao Y
Year: 2026
Journal: Cell Metab
Title: AMPK?2 signals amino acid insufficiency to inhibit protein synthesis.
Volume: 38
Issue: 1
Pages: 192-207.e8
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Publication
29113959 | J:260831
 
First Author: Lardenoije R
Year: 2018
Journal: Mol Cell Neurosci
Title: Age-related epigenetic changes in hippocampal subregions of four animal models of Alzheimer's disease.
Volume: 86
Pages: 1-15
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Publication
39103022 | J:366970
 
First Author: Ceyz?riat K
Year: 2024
Journal: Neurobiol Dis
Title: Inhibition of the mitochondrial pyruvate carrier in astrocytes reduces amyloid and tau accumulation in the 3xTgAD mouse model of Alzheimer's disease.
Volume: 200
Pages: 106623
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Publication
25622143 | J:274055
First Author: Orr AG
Year: 2015
Journal: Nat Neurosci
Title: Astrocytic adenosine receptor A2A and Gs-coupled signaling regulate memory.
Volume: 18
Issue: 3
Pages: 423-34
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Publication
26931567 | J:233816
First Author: Maeda S
Year: 2016
Journal: EMBO Rep
Title: Expression of A152T human tau causes age-dependent neuronal dysfunction and loss in transgenic mice.
Volume: 17
Issue: 4
Pages: 530-51
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Publication
30414727 | J:272048
 
First Author: Midani-Kur?ak JS
Year: 2019
Journal: Brain Res
Title: Effect of tau-pathology on charged multivesicular body protein 2b (CHMP2B).
Volume: 1706
Pages: 224-236
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Publication
32392471 | J:301449
First Author: Sauerbeck AD
Year: 2020
Journal: Neuron
Title: SEQUIN Multiscale Imaging of Mammalian Central Synapses Reveals Loss of Synaptic Connectivity Resulting from Diffuse Traumatic Brain Injury.
Volume: 107
Issue: 2
Pages: 257-273.e5
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Strain
MGI:8355280 | B6(Cg)-Psen2<tm1.1(PSEN2)Mdk> Tardbp<tm1.1(TARDBP)Mdk> Tmem106b<tm1.1(TMEM106B)Mdk> Snca<tm1.1(SNCA)Mdk> Isr(HSA17)1Mdk Psen1<tm1.1(PSEN1)Mdk> App<tm1.1(APP)Mdk>/J
Attribute String: mutant strain, targeted mutation, chromosome aberration
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Strain
MGI:8355281 | B6(Cg)-Psen2<tm1.1(PSEN2)Mdk> Tardbp<tm1.1(TARDBP)Mdk> Tmem106b<tm2.1(TMEM106B)Mdk> Snca<tm1.1(SNCA)Mdk> Isr(HSA17)1Mdk Psen1<tm1.1(PSEN1)Mdk> App<tm1.1(APP)Mdk>/J
Attribute String: chromosome aberration, mutant strain, targeted mutation
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Publication
29026079 | J:254398
First Author: Iwata T
Year: 2017
Journal: Nat Commun
Title: A long-range cis-regulatory element for class I odorant receptor genes.
Volume: 8
Issue: 1
Pages: 885
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Publication
19057621 | J:158080
First Author: Rodr?guez JJ
Year: 2009
Journal: Cell Death Differ
Title: Astroglia in dementia and Alzheimer's disease.
Volume: 16
Issue: 3
Pages: 378-85
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Publication
27022623 | J:240236
 
First Author: Shen X
Year: 2016
Journal: eNeuro
Title: Neurons in Vulnerable Regions of the Alzheimer's Disease Brain Display Reduced ATM Signaling.
Volume: 3
Issue: 1
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Publication
24305500 | J:286212
First Author: Reinert J
Year: 2014
Journal: J Alzheimers Dis
Title: A?38 in the brains of patients with sporadic and familial Alzheimer's disease and transgenic mouse models.
Volume: 39
Issue: 4
Pages: 871-81
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Publication
31213067 | J:277676
 
First Author: Findley CA
Year: 2019
Journal: ASN Neuro
Title: Amyloid Beta-Related Alterations to Glutamate Signaling Dynamics During Alzheimer's Disease Progression.
Volume: 11
Pages: 1759091419855541
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Publication
40604342 | J:369197
First Author: Akkaoui J
Year: 2025
Journal: J Cell Mol Med
Title: Robust Increase in IQCK Protein Expression in Mouse Models of Alzheimer's Disease and iPSC-Derived Neurons.
Volume: 29
Issue: 13
Pages: e70686
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Publication
37028406 | J:334726
First Author: Li YD
Year: 2023
Journal: Cell Stem Cell
Title: Activation of hypothalamic-enhanced adult-born neurons restores cognitive and affective function in Alzheimer's disease.
Volume: 30
Issue: 4
Pages: 415-432.e6
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Publication
26365177 | J:228348
First Author: Ishii M
Year: 2015
Journal: Cell Metab
Title: Metabolic and Non-Cognitive Manifestations of Alzheimer's Disease: The Hypothalamus as Both Culprit and Target of Pathology.
Volume: 22
Issue: 5
Pages: 761-76
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Publication
32727580 | J:311717
First Author: Kumar S
Year: 2020
Journal: Acta Neuropathol Commun
Title: Phosphorylated A? peptides in human Down syndrome brain and different Alzheimer's-like mouse models.
Volume: 8
Issue: 1
Pages: 118
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Publication
28694463 | J:249724
First Author: Dudeffant C
Year: 2017
Journal: Sci Rep
Title: Contrast-enhanced MR microscopy of amyloid plaques in five mouse models of amyloidosis and in human Alzheimer's disease brains.
Volume: 7
Issue: 1
Pages: 4955
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Publication
38776461 | J:360710
First Author: Kong Y
Year: 2024
Journal: ACS Chem Neurosci
Title: Increased Cerebral Level of P2X7R in a Tauopathy Mouse Model by PET Using [(18)F]GSK1482160.
Volume: 15
Issue: 11
Pages: 2112-2120
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Publication
41122803 | J:373943
First Author: Chaunsali L
Year: 2025
Journal: Alzheimers Dement
Title: Degradation of perineuronal nets in hippocampal CA2 explains the loss of social cognition memory in Alzheimer's disease.
Volume: 21
Issue: 10
Pages: e70813
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Publication
37463212 | J:344394
First Author: Cazzaro S
Year: 2023
Journal: Proc Natl Acad Sci U S A
Title: Slingshot homolog-1-mediated Nrf2 sequestration tips the balance from neuroprotection to neurodegeneration in Alzheimer's disease.
Volume: 120
Issue: 30
Pages: e2217128120
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Publication
37749326 | J:350128
First Author: Yin Z
Year: 2023
Journal: Nat Immunol
Title: APOE4 impairs the microglial response in Alzheimer's disease by inducing TGF?-mediated checkpoints.
Volume: 24
Issue: 11
Pages: 1839-1853
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Publication
34301831 | J:309391
First Author: Fleitas C
Year: 2021
Journal: J Neurosci
Title: FLRT2 and FLRT3 Cooperate in Maintaining the Tangential Migratory Streams of Cortical Interneurons during Development.
Volume: 41
Issue: 35
Pages: 7350-7362
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Publication
39813317 | J:361219
First Author: Brandao W
Year: 2025
Journal: Sci Transl Med
Title: Inhaled xenon modulates microglia and ameliorates disease in mouse models of amyloidosis and tauopathy.
Volume: 17
Issue: 781
Pages: eadk3690
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Publication
23747948 | J:199082
First Author: Frost JL
Year: 2013
Journal: Am J Pathol
Title: Pyroglutamate-3 amyloid-? deposition in the brains of humans, non-human primates, canines, and Alzheimer disease-like transgenic mouse models.
Volume: 183
Issue: 2
Pages: 369-81
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Publication
38462606 | J:347713
First Author: Zhong MZ
Year: 2024
Journal: Mol Neurodegener
Title: Updates on mouse models of Alzheimer's disease.
Volume: 19
Issue: 1
Pages: 23
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Publication
23833557 | J:202532
First Author: Lee JE
Year: 2013
Journal: Exp Neurobiol
Title: An update of animal models of Alzheimer disease with a reevaluation of plaque depositions.
Volume: 22
Issue: 2
Pages: 84-95
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Publication
25654552 | J:219892
First Author: Frake RA
Year: 2015
Journal: J Clin Invest
Title: Autophagy and neurodegeneration.
Volume: 125
Issue: 1
Pages: 65-74
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Publication
38343132 | J:347607
First Author: Benzow K
Year: 2024
Journal: Alzheimers Dement
Title: Gene replacement-Alzheimer's disease (GR-AD): Modeling the genetics of human dementias in mice.
Volume: 20
Issue: 4
Pages: 3080-3087
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Publication
- | J:82809
     
First Author: European Mouse Mutant Archive
Year: 2003
Journal: Unpublished
Title: Information obtained from the European Mouse Mutant Archive (EMMA)
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Publication
- | J:100256
     
First Author: The Gene Expression Nervous System Atlas (GENSAT) Project, The Rockefeller University (New York, NY)
Year: 2005
Journal: Database Download
Title: MGI download of GENSAT transgene data
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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