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Search results 3101 to 3200 out of 4141 for Mtor

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Type Details Score
Publication
21430043 | J:323464
First Author: Connor SA
Year: 2011
Journal: Learn Mem
Title: Fragile X mental retardation protein regulates heterosynaptic plasticity in the hippocampus.
Volume: 18
Issue: 4
Pages: 207-20
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21084617 | J:166442
First Author: Osterweil EK
Year: 2010
Journal: J Neurosci
Title: Hypersensitivity to mGluR5 and ERK1/2 leads to excessive protein synthesis in the hippocampus of a mouse model of fragile X syndrome.
Volume: 30
Issue: 46
Pages: 15616-27
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Publication
23542787 | J:198359
First Author: Busquets-Garcia A
Year: 2013
Journal: Nat Med
Title: Targeting the endocannabinoid system in the treatment of fragile X syndrome.
Volume: 19
Issue: 5
Pages: 603-7
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Publication
24284511 | J:323152
First Author: Wallace DP
Year: 2014
Journal: Kidney Int
Title: Periostin promotes renal cyst growth and interstitial fibrosis in polycystic kidney disease.
Volume: 85
Issue: 4
Pages: 845-54
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Publication
24785297 | J:211065
First Author: Park H
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Metabolic regulator Fnip1 is crucial for iNKT lymphocyte development.
Volume: 111
Issue: 19
Pages: 7066-71
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Publication
23321674 | J:194490
First Author: Thiem S
Year: 2013
Journal: J Clin Invest
Title: mTORC1 inhibition restricts inflammation-associated gastrointestinal tumorigenesis in mice.
Volume: 123
Issue: 2
Pages: 767-81
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Publication
28740109 | J:250222
First Author: Cosin-Roger J
Year: 2017
Journal: Nat Commun
Title: Hypoxia ameliorates intestinal inflammation through NLRP3/mTOR downregulation and autophagy activation.
Volume: 8
Issue: 1
Pages: 98
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Publication
27482882 | J:237255
First Author: Cheng HY
Year: 2016
Journal: J Clin Invest
Title: Loss of ABCG1 influences regulatory T cell differentiation and atherosclerosis.
Volume: 126
Issue: 9
Pages: 3236-46
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Publication
26848161 | J:246067
First Author: Babaev VR
Year: 2016
Journal: Arterioscler Thromb Vasc Biol
Title: Macrophage IKKα Deficiency Suppresses Akt Phosphorylation, Reduces Cell Survival, and Decreases Early Atherosclerosis.
Volume: 36
Issue: 4
Pages: 598-607
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Publication
23816567 | J:204115
First Author: Zhang J
Year: 2013
Journal: Biochim Biophys Acta
Title: Phosphorylation and degradation of S6K1 (p70S6K1) in response to persistent JNK1 Activation.
Volume: 1832
Issue: 12
Pages: 1980-8
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Publication
34054815 | J:314529
 
First Author: McKell MC
Year: 2021
Journal: Front Immunol
Title: Promotion of Anti-Tuberculosis Macrophage Activity by L-Arginine in the Absence of Nitric Oxide.
Volume: 12
Pages: 653571
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20696947 | J:166648
First Author: Geng D
Year: 2010
Journal: Blood
Title: When Toll-like receptor and T-cell receptor signals collide: a mechanism for enhanced CD8 T-cell effector function.
Volume: 116
Issue: 18
Pages: 3494-504
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Publication
30914432 | J:276357
First Author: Malakar P
Year: 2019
Journal: Cancer Res
Title: Long Noncoding RNA MALAT1 Regulates Cancer Glucose Metabolism by Enhancing mTOR-Mediated Translation of TCF7L2.
Volume: 79
Issue: 10
Pages: 2480-2493
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21212363 | J:168259
First Author: Guo W
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Suppression of leukemia development caused by PTEN loss.
Volume: 108
Issue: 4
Pages: 1409-14
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17510408 | J:121729
First Author: Sandsmark DK
Year: 2007
Journal: Cancer Res
Title: Nucleophosmin mediates mammalian target of rapamycin-dependent actin cytoskeleton dynamics and proliferation in neurofibromin-deficient astrocytes.
Volume: 67
Issue: 10
Pages: 4790-9
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32231246 | J:302726
First Author: Damgaard RB
Year: 2020
Journal: Cell Death Differ
Title: OTULIN protects the liver against cell death, inflammation, fibrosis, and cancer.
Volume: 27
Issue: 5
Pages: 1457-1474
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Publication
26190969 | J:323486
 
First Author: Wang T
Year: 2015
Journal: Front Cell Neurosci
Title: In vivo synaptic transmission and morphology in mouse models of Tuberous sclerosis, Fragile X syndrome, Neurofibromatosis type 1, and Costello syndrome.
Volume: 9
Pages: 234
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Publication
30858178 | J:277892
First Author: Dhar SK
Year: 2019
Journal: J Biol Chem
Title: UVB-induced inactivation of manganese-containing superoxide dismutase promotes mitophagy via ROS-mediated mTORC2 pathway activation.
Volume: 294
Issue: 17
Pages: 6831-6842
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23328844 | J:317952
First Author: Delisle JS
Year: 2013
Journal: Genes Immun
Title: The TGF-β-Smad3 pathway inhibits CD28-dependent cell growth and proliferation of CD4 T cells.
Volume: 14
Issue: 2
Pages: 115-26
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20080688 | J:156532
First Author: Hung KE
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Development of a mouse model for sporadic and metastatic colon tumors and its use in assessing drug treatment.
Volume: 107
Issue: 4
Pages: 1565-70
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24430184 | J:207982
First Author: Li H
Year: 2014
Journal: J Clin Invest
Title: Inactivation of SAG/RBX2 E3 ubiquitin ligase suppresses KrasG12D-driven lung tumorigenesis.
Volume: 124
Issue: 2
Pages: 835-46
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25813352 | J:223572
First Author: Van Nostrand JL
Year: 2015
Journal: Cancer Discov
Title: The p53 Target Gene SIVA Enables Non-Small Cell Lung Cancer Development.
Volume: 5
Issue: 6
Pages: 622-35
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22725947 | J:317543
First Author: Stayner C
Year: 2012
Journal: Nephrology (Carlton)
Title: Rapamycin-mediated suppression of renal cyst expansion in del34 Pkd1-/- mutant mouse embryos: an investigation of the feasibility of renal cyst prevention in the foetus.
Volume: 17
Issue: 8
Pages: 739-47
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18845692 | J:143404
First Author: Hartman TR
Year: 2009
Journal: Hum Mol Genet
Title: The tuberous sclerosis proteins regulate formation of the primary cilium via a rapamycin-insensitive and polycystin 1-independent pathway.
Volume: 18
Issue: 1
Pages: 151-63
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28422956 | J:246525
First Author: Jo E
Year: 2017
Journal: PLoS One
Title: Chronic activation of PPARα with fenofibrate reduces autophagic proteins in the liver of mice independent of FGF21.
Volume: 12
Issue: 4
Pages: e0173676
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27928028 | J:251815
First Author: Ghosh A
Year: 2016
Journal: Sci Transl Med
Title: Mitochondrial pyruvate carrier regulates autophagy, inflammation, and neurodegeneration in experimental models of Parkinson's disease.
Volume: 8
Issue: 368
Pages: 368ra174
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19887628 | J:154764
First Author: Schoeftner S
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: Telomere shortening relaxes X chromosome inactivation and forces global transcriptome alterations.
Volume: 106
Issue: 46
Pages: 19393-8
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19443706 | J:148919
First Author: Rodriguez OC
Year: 2009
Journal: Am J Pathol
Title: A reduction in Pten tumor suppressor activity promotes ErbB-2-induced mouse prostate adenocarcinoma formation through the activation of signaling cascades downstream of PDK1.
Volume: 174
Issue: 6
Pages: 2051-60
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16027168 | J:100094
First Author: Ma L
Year: 2005
Journal: Genes Dev
Title: Genetic analysis of Pten and Tsc2 functional interactions in the mouse reveals asymmetrical haploinsufficiency in tumor suppression.
Volume: 19
Issue: 15
Pages: 1779-86
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20051384 | J:176109
First Author: Furgeson SB
Year: 2010
Journal: Cardiovasc Res
Title: Inactivation of the tumour suppressor, PTEN, in smooth muscle promotes a pro-inflammatory phenotype and enhances neointima formation.
Volume: 86
Issue: 2
Pages: 274-82
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Publication
37108467 | J:335265
 
First Author: GÄ…ssowska-Dobrowolska M
Year: 2023
Journal: Int J Mol Sci
Title: Microtubule Cytoskeletal Network Alterations in a Transgenic Model of Tuberous Sclerosis Complex: Relevance to Autism Spectrum Disorders.
Volume: 24
Issue: 8
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34576223 | J:313693
 
First Author: Czapski GA
Year: 2021
Journal: Int J Mol Sci
Title: Synaptic Alterations in a Transgenic Model of Tuberous Sclerosis Complex: Relevance to Autism Spectrum Disorders.
Volume: 22
Issue: 18
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19321600 | J:148543
First Author: Bonnet CS
Year: 2009
Journal: Hum Mol Genet
Title: Defects in cell polarity underlie TSC and ADPKD-associated cystogenesis.
Volume: 18
Issue: 12
Pages: 2166-76
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15578690 | J:95229
First Author: Lee L
Year: 2005
Journal: Genes Chromosomes Cancer
Title: Efficacy of a rapamycin analog (CCI-779) and IFN-gamma in tuberous sclerosis mouse models.
Volume: 42
Issue: 3
Pages: 213-27
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20159776 | J:159339
First Author: Cao J
Year: 2010
Journal: Hum Mol Genet
Title: Thoracic aortic disease in tuberous sclerosis complex: molecular pathogenesis and potential therapies in Tsc2+/- mice.
Volume: 19
Issue: 10
Pages: 1908-20
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19602587 | J:150957
First Author: Huang J
Year: 2009
Journal: Cancer Res
Title: Signaling events downstream of mammalian target of rapamycin complex 2 are attenuated in cells and tumors deficient for the tuberous sclerosis complex tumor suppressors.
Volume: 69
Issue: 15
Pages: 6107-14
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34667149 | J:351267
First Author: Pagani M
Year: 2021
Journal: Nat Commun
Title: mTOR-related synaptic pathology causes autism spectrum disorder-associated functional hyperconnectivity.
Volume: 12
Issue: 1
Pages: 6084
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19527517 | J:157342
 
First Author: Pollizzi K
Year: 2009
Journal: Mol Cancer
Title: Equivalent benefit of mTORC1 blockade and combined PI3K-mTOR blockade in a mouse model of tuberous sclerosis.
Volume: 8
Pages: 38
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37127876 | J:350441
First Author: Unachukwu U
Year: 2023
Journal: Mol Cancer Ther
Title: Tyrosine Kinase Inhibitors Diminish Renal Neoplasms in a Tuberous Sclerosis Model Via Induction of Apoptosis.
Volume: 22
Issue: 7
Pages: 844-858
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26240281 | J:228222
First Author: Nakagawa T
Year: 2015
Journal: Mol Cell Biol
Title: S6 Kinase- and β-TrCP2-Dependent Degradation of p19Arf Is Required for Cell Proliferation.
Volume: 35
Issue: 20
Pages: 3517-27
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14625550 | J:86737
First Author: Aoki K
Year: 2003
Journal: Nat Genet
Title: Colonic polyposis caused by mTOR-mediated chromosomal instability in Apc+/Delta716 Cdx2+/- compound mutant mice.
Volume: 35
Issue: 4
Pages: 323-30
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20818428 | J:164579
First Author: Ahmad I
Year: 2011
Journal: Oncogene
Title: β-Catenin activation synergizes with PTEN loss to cause bladder cancer formation.
Volume: 30
Issue: 2
Pages: 178-89
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21903772 | J:232844
First Author: Wu R
Year: 2011
Journal: Clin Cancer Res
Title: Preclinical testing of PI3K/AKT/mTOR signaling inhibitors in a mouse model of ovarian endometrioid adenocarcinoma.
Volume: 17
Issue: 23
Pages: 7359-72
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Publication
35971771 | J:328707
   
First Author: Romero-Becerra R
Year: 2022
Journal: Elife
Title: MKK6 deficiency promotes cardiac dysfunction through MKK3-p38γ/δ-mTOR hyperactivation.
Volume: 11
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30126999 | J:265537
First Author: Kaur G
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: Aberrant early endosome biogenesis mediates complement activation in the retinal pigment epithelium in models of macular degeneration.
Volume: 115
Issue: 36
Pages: 9014-9019
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Publication
28408298 | J:249407
 
First Author: Lima IVA
Year: 2017
Journal: Behav Brain Res
Title: Antidepressant-like effect of valproic acid-Possible involvement of PI3K/Akt/mTOR pathway.
Volume: 329
Pages: 166-171
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Publication
25339759 | J:217151
First Author: Shibuya Y
Year: 2014
Journal: J Neurosci
Title: Inhibiting ACAT1/SOAT1 in microglia stimulates autophagy-mediated lysosomal proteolysis and increases Aβ1-42 clearance.
Volume: 34
Issue: 43
Pages: 14484-501
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20686448 | J:184250
First Author: Zafar I
Year: 2010
Journal: Kidney Int
Title: Sirolimus attenuates disease progression in an orthologous mouse model of human autosomal dominant polycystic kidney disease.
Volume: 78
Issue: 8
Pages: 754-61
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36443301 | J:331960
First Author: Huang Z
Year: 2022
Journal: Nat Commun
Title: mTORC1 links pathology in experimental models of Still's disease and macrophage activation syndrome.
Volume: 13
Issue: 1
Pages: 6915
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26367276 | J:245813
First Author: Nanjappa SG
Year: 2015
Journal: PLoS Pathog
Title: Intrinsic MyD88-Akt1-mTOR Signaling Coordinates Disparate Tc17 and Tc1 Responses during Vaccine Immunity against Fungal Pneumonia.
Volume: 11
Issue: 9
Pages: e1005161
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29445008 | J:261313
First Author: Mohammadpour H
Year: 2018
Journal: J Immunol
Title: Blockade of Host β2-Adrenergic Receptor Enhances Graft-versus-Tumor Effect through Modulating APCs.
Volume: 200
Issue: 7
Pages: 2479-2488
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22351927 | J:181685
First Author: Bakkar N
Year: 2012
Journal: J Cell Biol
Title: IKKα and alternative NF-κB regulate PGC-1β to promote oxidative muscle metabolism.
Volume: 196
Issue: 4
Pages: 497-511
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29864452 | J:264085
 
First Author: Montesinos J
Year: 2018
Journal: Neurosci Lett
Title: Binge-like ethanol treatment in adolescence impairs autophagy and hinders synaptic maturation: Role of TLR4.
Volume: 682
Pages: 85-91
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23698118 | J:200847
First Author: Watts BA 3rd
Year: 2013
Journal: Am J Physiol Renal Physiol
Title: Lumen LPS inhibits HCO3(-) absorption in the medullary thick ascending limb through TLR4-PI3K-Akt-mTOR-dependent inhibition of basolateral Na+/H+ exchange.
Volume: 305
Issue: 4
Pages: F451-62
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23928372 | J:203269
First Author: Lin Y
Year: 2013
Journal: Endocrinology
Title: Genetic deficiency of anti-aging gene klotho exacerbates early nephropathy in STZ-induced diabetes in male mice.
Volume: 154
Issue: 10
Pages: 3855-63
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26019056 | J:227440
 
First Author: Prabhakar S
Year: 2015
Journal: Neurobiol Dis
Title: Survival benefit and phenotypic improvement by hamartin gene therapy in a tuberous sclerosis mouse brain model.
Volume: 82
Pages: 22-31
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22025691 | J:180260
First Author: Goto J
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Regulable neural progenitor-specific Tsc1 loss yields giant cells with organellar dysfunction in a model of tuberous sclerosis complex.
Volume: 108
Issue: 45
Pages: E1070-9
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37640003 | J:341094
 
First Author: Yamaguchi H
Year: 2023
Journal: Biochem Biophys Res Commun
Title: Enhanced BMP signaling leads to enlarged nasal cartilage formation in mice.
Volume: 678
Pages: 173-178
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32927859 | J:306401
 
First Author: Guijarro MV
Year: 2020
Journal: Cells
Title: Tsc1 Regulates the Proliferation Capacity of Bone-Marrow Derived Mesenchymal Stem Cells.
Volume: 9
Issue: 9
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24170201 | J:206514
First Author: Tanwar PS
Year: 2014
Journal: Carcinogenesis
Title: Loss of LKB1 and PTEN tumor suppressor genes in the ovarian surface epithelium induces papillary serous ovarian cancer.
Volume: 35
Issue: 3
Pages: 546-53
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32591410 | J:296309
First Author: Yamauchi Y
Year: 2020
Journal: Cancer Res
Title: Rb and p53 Execute Distinct Roles in the Development of Pancreatic Neuroendocrine Tumors.
Volume: 80
Issue: 17
Pages: 3620-3630
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25639352 | J:232674
First Author: Fang F
Year: 2015
Journal: J Bone Miner Res
Title: Neural Crest-Specific TSC1 Deletion in Mice Leads to Sclerotic Craniofacial Bone Lesion.
Volume: 30
Issue: 7
Pages: 1195-205
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19435901 | J:148476
First Author: Raimondi AR
Year: 2009
Journal: Cancer Res
Title: Rapamycin prevents early onset of tumorigenesis in an oral-specific K-ras and p53 two-hit carcinogenesis model.
Volume: 69
Issue: 10
Pages: 4159-66
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35432387 | J:323899
 
First Author: Torp MK
Year: 2022
Journal: Front Immunol
Title: Intracellular Complement Component 3 Attenuated Ischemia-Reperfusion Injury in the Isolated Buffer-Perfused Mouse Heart and Is Associated With Improved Metabolic Homeostasis.
Volume: 13
Pages: 870811
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24064341 | J:205003
First Author: Auffret J
Year: 2013
Journal: Am J Physiol Endocrinol Metab
Title: Defective prolactin signaling impairs pancreatic β-cell development during the perinatal period.
Volume: 305
Issue: 10
Pages: E1309-18
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33953172 | J:317913
First Author: Liu Y
Year: 2021
Journal: Cell Death Dis
Title: Stimulation of α7-nAChRs coordinates autophagy and apoptosis signaling in experimental knee osteoarthritis.
Volume: 12
Issue: 5
Pages: 448
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36125265 | J:330376
First Author: Riehle C
Year: 2022
Journal: Mol Cell Biol
Title: Insulin and Insulin-Like Growth Factor 1 Signaling Preserves Sarcomere Integrity in the Adult Heart.
Volume: 42
Issue: 10
Pages: e0016322
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31167126 | J:283524
First Author: Yang L
Year: 2019
Journal: Biochim Biophys Acta Mol Basis Dis
Title: CD74 knockout attenuates alcohol intake-induced cardiac dysfunction through AMPK-Skp2-mediated regulation of autophagy.
Volume: 1865
Issue: 9
Pages: 2368-2378
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34637854 | J:322126
 
First Author: Francija E
Year: 2022
Journal: Behav Brain Res
Title: GluN2A-ERK-mTOR pathway confers a vulnerability to LPS-induced depressive-like behaviour.
Volume: 417
Pages: 113625
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27402081 | J:234915
First Author: Meng X
Year: 2016
Journal: Cancer Res
Title: RPL23 Links Oncogenic RAS Signaling to p53-Mediated Tumor Suppression.
Volume: 76
Issue: 17
Pages: 5030-9
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17699716 | J:138101
First Author: Mosley JD
Year: 2007
Journal: Mol Cancer Ther
Title: Rapamycin inhibits multiple stages of c-Neu/ErbB2 induced tumor progression in a transgenic mouse model of HER2-positive breast cancer.
Volume: 6
Issue: 8
Pages: 2188-97
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23454899 | J:200122
First Author: Molina-Arcas M
Year: 2013
Journal: Cancer Discov
Title: Coordinate direct input of both KRAS and IGF1 receptor to activation of PI3 kinase in KRAS-mutant lung cancer.
Volume: 3
Issue: 5
Pages: 548-63
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28847987 | J:317020
First Author: Akeno N
Year: 2017
Journal: Mol Cancer Ther
Title: TRP53 Mutants Drive Neuroendocrine Lung Cancer Through Loss-of-Function Mechanisms with Gain-of-Function Effects on Chemotherapy Response.
Volume: 16
Issue: 12
Pages: 2913-2926
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23851502 | J:212578
First Author: Guo Y
Year: 2014
Journal: Oncogene
Title: Tsc1-Tp53 loss induces mesothelioma in mice, and evidence for this mechanism in human mesothelioma.
Volume: 33
Issue: 24
Pages: 3151-60
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29938573 | J:302615
First Author: Yeo SK
Year: 2018
Journal: Autophagy
Title: Improved efficacy of mitochondrial disrupting agents upon inhibition of autophagy in a mouse model of BRCA1-deficient breast cancer.
Volume: 14
Issue: 7
Pages: 1214-1225
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31356902 | J:280572
 
First Author: Gao H
Year: 2019
Journal: Life Sci
Title: UCHL1 regulates muscle fibers and mTORC1 activity in skeletal muscle.
Volume: 233
Pages: 116699
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23630012 | J:198770
First Author: Nemazanyy I
Year: 2013
Journal: EMBO Mol Med
Title: Defects of Vps15 in skeletal muscles lead to autophagic vacuolar myopathy and lysosomal disease.
Volume: 5
Issue: 6
Pages: 870-90
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24145720 | J:338042
First Author: Puppa MJ
Year: 2014
Journal: FASEB J
Title: Skeletal muscle glycoprotein 130's role in Lewis lung carcinoma-induced cachexia.
Volume: 28
Issue: 2
Pages: 998-1009
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39356748 | J:359223
First Author: Zhou L
Year: 2024
Journal: Sci Transl Med
Title: Glucocorticoids induce a maladaptive epithelial stress response to aggravate acute kidney injury.
Volume: 16
Issue: 767
Pages: eadk5005
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Publication
36766792 | J:336276
 
First Author: Meyer-Heemsoth L
Year: 2023
Journal: Cells
Title: T Cell Energy Metabolism Is a Target of Glucocorticoids in Mice, Healthy Humans, and MS Patients.
Volume: 12
Issue: 3
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33802976 | J:321010
 
First Author: Tirronen A
Year: 2021
Journal: Biomolecules
Title: The Ablation of VEGFR-1 Signaling Promotes Pressure Overload-Induced Cardiac Dysfunction and Sudden Death.
Volume: 11
Issue: 3
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Publication
36198355 | J:330645
 
First Author: Zaradzki M
Year: 2022
Journal: Biochem Pharmacol
Title: Short-term rapamycin treatment increases life span and attenuates aortic aneurysm in a murine model of Marfan-Syndrome.
Volume: 205
Pages: 115280
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Publication
29501742 | J:273677
First Author: Li H
Year: 2018
Journal: Biochem Biophys Res Commun
Title: FTO is involved in Alzheimer's disease by targeting TSC1-mTOR-Tau signaling.
Volume: 498
Issue: 1
Pages: 234-239
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Publication
33841077 | J:348494
 
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