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Search results 3101 to 3200 out of 6467 for Myc

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Hits by Strain

Type Details Score
Allele
Col1a1<tm1(tetO-St8sia6)Viss> | MGI:6453872
Name: collagen, type I, alpha 1; targeted mutation 1, Virginia Smith Shapiro
Allele Type: Targeted
Attribute String: Epitope tag, Inserted expressed sequence
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Allele
Gt(ROSA)26Sor<tm1(CAG-Axin1,-lacZ)Kini> | MGI:6726261
Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Karolinska Institutet
Allele Type: Targeted
Attribute String: Conditional ready, Inserted expressed sequence, Reporter
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Allele
Bmp4<tm3Jlch> | MGI:7413958
Name: bone morphogenetic protein 4; targeted mutation 3, Jan L Christian
Allele Type: Targeted
Attribute String: Epitope tag
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Allele
Myc<em2Smoc> | MGI:7291200
Name: myelocytomatosis oncogene; endonuclease-mediated mutation 2, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
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Allele
Myc<tm1Smoc> | MGI:7291201
Name: myelocytomatosis oncogene; targeted mutation 1, Shanghai Model Organisms Center
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
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Allele
Sorl1<em1Smoc> | MGI:7292527
Name: sortilin-related receptor, LDLR class A repeats-containing; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
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Strain
MGI:7427377 | C57BL/6J-Tg(Vav1-MYC)10Sco/J
Attribute String: coisogenic, mutant strain, transgenic
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Strain
MGI:6145863 | B6.Cg-Dnaaf6rt<tm1Hmd>/HmdRbrc
Attribute String: mutant strain, congenic, targeted mutation
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Allele
Gt(ROSA)26Sor<tm3(CAG-MYC/ERT2)Gev> | MGI:7464360
Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 3, Gerard Evan
Allele Type: Targeted
Attribute String: Conditional ready, Inducible, Inserted expressed sequence, Reporter
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Allele
Col1a1<tm5.1(tetO-Myc,-mCherry)Yasu> | MGI:7509703
Name: collagen, type I, alpha 1; targeted mutation 5.1, Yasuhiro Yamada
Allele Type: Targeted
Attribute String: Inducible, Inserted expressed sequence, Reporter
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Allele
Tg(Myh6-Mybpc3*)34Rbns | MGI:7547411
Name: transgene insertion 34, Jeffrey Robbins
Allele Type: Transgenic
Attribute String: Constitutively active, Epitope tag, Inserted expressed sequence
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Genotype
Genotype
Symbol: Hprt1/?
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Hprt1/Hprt1
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Hprt1/?
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Hprt1/Hprt1
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Axin1/Axin1
Background: involves: 129S6/SvEvTac * FVB/N
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Rp1/Rp1
Background: involves: 129S6/SvEvTac
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Rp1/Rp1<+>
Background: involves: 129S6/SvEvTac * C57BL/6
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Rp1/Rp1
Background: involves: 129S6/SvEvTac * C57BL/6
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Del(15Rr357-Rr303293)2Jta/Del(15Rr357-Rr303293)2Jta
Background: involves: C57BL/6
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(IghMyc)186Brn/? Rpl38/Rpl38<+>
Background: involves: C57BL/LiA * CBA/BrA
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Trim63/Trim63
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Pkd1/Pkd1
Background: involves: 129S2/SvPas * C57BL/6 * C57BL/6NTac
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Del(15Rr21-Rr303293)1Jta/Del(15Rr21-Rr303293)1Jta
Background: involves: C57BL/6
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(Ela1-Myc)159Bri/?
Background: involves: C57BL/6 * SJL
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Pknox1/Pknox1<+> Tg(IghMyc)22Bri/?
Background: involves: C57BL * SJL
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(H2-K-IL6)2Srj/?
Background: B6.Cg-Tg(H2-K-IL6)2Srj
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Dnaaf6rt/Dnaaf6rt
Background: involves: ICR
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Rr38/Rr38<+>
Background: involves: 129S4/SvJaeSor * BALB/cJ * C57BL/6
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Rr38/Rr38
Background: involves: 129S4/SvJaeSor * BALB/cJ * C57BL/6
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Dnaaf6rt/Dnaaf6rt<+>
Background: involves: ICR
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+>
Background: involves: C57BL/6
Zygosity: ht
Has Mutant Allele: true
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Publication
22863009 | J:187885
First Author: Rounbehler RJ
Year: 2012
Journal: Cell
Title: Tristetraprolin impairs myc-induced lymphoma and abolishes the malignant state.
Volume: 150
Issue: 3
Pages: 563-74
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Publication
24605938 | J:326984
First Author: Ontiveros EP
Year: 2014
Journal: Leuk Lymphoma
Title: A new model of LMP1-MYC interaction in B cell lymphoma.
Volume: 55
Issue: 12
Pages: 2917-23
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Publication
30954402 | J:275675
First Author: Filipponi D
Year: 2019
Journal: Mol Cell
Title: DNA Damage Signaling-Induced Cancer Cell Reprogramming as a Driver of Tumor Relapse.
Volume: 74
Issue: 4
Pages: 651-663.e8
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Publication
25176652 | J:233951
First Author: Muthalagu N
Year: 2014
Journal: Cell Rep
Title: BIM is the primary mediator of MYC-induced apoptosis in multiple solid tissues.
Volume: 8
Issue: 5
Pages: 1347-53
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Publication
11086005 | J:77658
First Author: Previtali SC
Year: 2000
Journal: J Cell Biol
Title: Epitope-tagged P(0) glycoprotein causes Charcot-Marie-Tooth-like neuropathy in transgenic mice.
Volume: 151
Issue: 5
Pages: 1035-46
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Publication
14522256 | J:85480
First Author: Ellwood-Yen K
Year: 2003
Journal: Cancer Cell
Title: Myc-driven murine prostate cancer shares molecular features with human prostate tumors.
Volume: 4
Issue: 3
Pages: 223-38
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Publication
36270281 | J:331103
First Author: Chondronasiou D
Year: 2022
Journal: Stem Cell Reports
Title: Deciphering the roadmap of in vivo reprogramming toward pluripotency.
Volume: 17
Issue: 11
Pages: 2501-2517
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Publication
17363561 | J:120309
First Author: Qi CF
Year: 2007
Journal: Cancer Res
Title: Anaplastic, plasmablastic, and plasmacytic plasmacytomas of mice: relationships to human plasma cell neoplasms and late-stage differentiation of normal B cells.
Volume: 67
Issue: 6
Pages: 2439-47
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Publication
22081075 | J:186117
First Author: Mérino D
Year: 2012
Journal: Oncogene
Title: Bim must be able to engage all pro-survival Bcl-2 family members for efficient tumor suppression.
Volume: 31
Issue: 28
Pages: 3392-6
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Publication
22039254 | J:179064
First Author: Bieging KT
Year: 2011
Journal: Blood
Title: A shared gene expression signature in mouse models of EBV-associated and non-EBV-associated Burkitt lymphoma.
Volume: 118
Issue: 26
Pages: 6849-59
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Publication
24723682 | J:213131
First Author: Hope C
Year: 2014
Journal: Blood
Title: TPL2 kinase regulates the inflammatory milieu of the myeloma niche.
Volume: 123
Issue: 21
Pages: 3305-15
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Publication
20440272 | J:162024
First Author: Osborne LC
Year: 2010
Journal: Oncogene
Title: Selective ablation of the YxxM motif of IL-7Ralpha suppresses lymphomagenesis but maintains lymphocyte development.
Volume: 29
Issue: 26
Pages: 3854-64
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Publication
34363012 | J:310831
First Author: Lewis R
Year: 2021
Journal: Leukemia
Title: CXCR4 hyperactivation cooperates with TCL1 in CLL development and aggressiveness.
Volume: 35
Issue: 10
Pages: 2895-2905
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Publication
10597314 | J:59021
First Author: Vaillant F
Year: 1999
Journal: Oncogene
Title: A full-length Cbfa1 gene product perturbs T-cell development and promotes lymphomagenesis in synergy with myc.
Volume: 18
Issue: 50
Pages: 7124-34
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Publication
15735016 | J:96785
First Author: Park SS
Year: 2005
Journal: Cancer Res
Title: Insertion of c-Myc into Igh induces B-cell and plasma-cell neoplasms in mice.
Volume: 65
Issue: 4
Pages: 1306-15
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Publication
24727894 | J:221282
First Author: Nopparat J
Year: 2015
Journal: Oncogene
Title: δ-Catenin, a Wnt/β-catenin modulator, reveals inducible mutagenesis promoting cancer cell survival adaptation and metabolic reprogramming.
Volume: 34
Issue: 12
Pages: 1542-52
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Publication
19182823 | J:147588
First Author: Bultema R
Year: 2009
Journal: Oncogene
Title: Epstein-Barr virus LMP2A accelerates MYC-induced lymphomagenesis.
Volume: 28
Issue: 11
Pages: 1471-6
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Publication
25980500 | J:307928
First Author: Saad F
Year: 2015
Journal: Oncotarget
Title: The IgH 3' regulatory region influences lymphomagenesis in Igλ-Myc mice.
Volume: 6
Issue: 24
Pages: 20302-11
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Publication
21697285 | J:174205
First Author: Mehta HH
Year: 2011
Journal: Cancer Res
Title: IGFBP-3 is a metastasis suppression gene in prostate cancer.
Volume: 71
Issue: 15
Pages: 5154-63
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HT Experiment
GSE164990 | BAF subunit switching regulates chromatin accessibility to control cell cycle exit in the developing mammalian cortex [RNA-seq]
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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HT Experiment
GSE228531 | Hyperpolarization-Activated Cyclic Nucleotide-Gated Potassium Channel 3 Promotes HCC Development in a Female-biased Manner
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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HT Experiment
GSE132438 | Fc receptor-like 6 (FCRL6) defines pre-BCR dependent and independent pathways of natural antibody selection
 
Experiment Type: RNA-Seq
Study Type: Baseline
Source: GEO
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HT Experiment
GSE137132 | Interaction of YAP1 with the Myb-MuvB (MMB) complex sustain proliferation in the postnatal heart
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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HT Experiment
GSE107727 | A single cell hematopoietic landscape resolves 8 lineage trajectories and defects in Kit mutant mice
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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Publication
7478514 | J:29977
First Author: Asker CE
Year: 1995
Journal: Oncogene
Title: Mouse and rat B-myc share amino acid sequence homology with the c-myc transcriptional activator domain and contain a B-myc specific carboxy terminal region.
Volume: 11
Issue: 10
Pages: 1963-9
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Publication
10233843 | J:79839
First Author: Sargent LM
Year: 1999
Journal: Am J Pathol
Title: Nonrandom cytogenetic alterations in hepatocellular carcinoma from transgenic mice overexpressing c-Myc and transforming growth factor-alpha in the liver.
Volume: 154
Issue: 4
Pages: 1047-55
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Protein
Q9Z197
Organism: Mus musculus/domesticus
Length: 77  
Fragment?: true
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Protein
O88594
Organism: Mus musculus/domesticus
Length: 104  
Fragment?: true
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Protein
B1ARS4
Organism: Mus musculus/domesticus
Length: 72  
Fragment?: true
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Protein Domain
IPR012682 | Tscrpt_reg_Myc_N
Type: Domain
Description: The class III basic helix-turn-helix (bHLH) transcription factors have proliferative and apoptotic roles and are characterised by the presence of a leucine zipper adjacent to the bHLH domain. The myc oncogene gene was first discovered in small-cell lung cancer cell lines where it is found to be deregulated []. Although the biochemical function of the gene product is unknown, as a nuclear protein with a short half-life it may play a direct or indirect role in controlling gene expression []. Myc forms a heterodimer with Max, and this complex regulates cell growth through direct activation of genes involved in cell replication [].This entry represents the N-terminal domain found adjacent to the basic helix-loop-helix (bHLH) region ().
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Protein
Q9D0M2
Organism: Mus musculus/domesticus
Length: 382  
Fragment?: false
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Publication
20227040 | J:158660
First Author: Reimann M
Year: 2010
Journal: Cancer Cell
Title: Tumor stroma-derived TGF-beta limits myc-driven lymphomagenesis via Suv39h1-dependent senescence.
Volume: 17
Issue: 3
Pages: 262-72
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Publication
11593398 | -
First Author: Bannasch D
Year: 2001
Journal: Oncogene
Title: Functional interaction of Yaf2 with the central region of MycN.
Volume: 20
Issue: 41
Pages: 5913-9
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Publication
7889571 | J:31509
First Author: Schreiber-Agus N
Year: 1995
Journal: Cell
Title: An amino-terminal domain of Mxi1 mediates anti-Myc oncogenic activity and interacts with a homolog of the yeast transcriptional repressor SIN3.
Volume: 80
Issue: 5
Pages: 777-86
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Publication
19061831 | J:142032
First Author: Freie BW
Year: 2008
Journal: Cancer Cell
Title: Ratcheting Myc.
Volume: 14
Issue: 6
Pages: 425-6
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Publication
16482495 | J:107719
First Author: Kim JS
Year: 2006
Journal: J Pathol
Title: Plasma cell tumour progression in iMycEmu gene-insertion mice.
Volume: 209
Issue: 1
Pages: 44-55
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Publication
35605249 | J:327047
First Author: Ikeda M
Year: 2022
Journal: Blood Adv
Title: Latent membrane proteins from EBV differentially target cellular pathways to accelerate MYC-induced lymphomagenesis.
Volume: 6
Issue: 14
Pages: 4283-4296
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Protein Coding Gene
MGI:88184 | Bmyc
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
32737294 | J:331939
First Author: Keil JM
Year: 2020
Journal: Nat Commun
Title: Symmetric neural progenitor divisions require chromatin-mediated homologous recombination DNA repair by Ino80.
Volume: 11
Issue: 1
Pages: 3839
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Publication
31197172 | J:278483
First Author: Shi L
Year: 2019
Journal: Nat Commun
Title: Robust elimination of genome-damaged cells safeguards against brain somatic aneuploidy following Knl1 deletion.
Volume: 10
Issue: 1
Pages: 2588
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Publication
38684366 | J:352327
 
First Author: Matúš D
Year: 2024
Journal: J Neurosci
Title: Essential Role of Latrophilin-1 Adhesion GPCR Nanoclusters in Inhibitory Synapses.
Volume: 44
Issue: 23
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Publication
35145326 | J:330715
First Author: Hirano M
Year: 2022
Journal: Nat Metab
Title: MYCL-mediated reprogramming expands pancreatic insulin-producing cells.
Volume: 4
Issue: 2
Pages: 254-268
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Publication
24771135 | J:216527
First Author: Hömberg N
Year: 2014
Journal: Int J Cancer
Title: CD40-independent natural killer-cell help promotes dendritic cell vaccine-induced T-cell immunity against endogenous B-cell lymphoma.
Volume: 135
Issue: 12
Pages: 2825-33
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Publication
10197595 | J:54359
First Author: Berns A
Year: 1999
Journal: Cancer Res
Title: Identification and characterization of collaborating oncogenes in compound mutant mice.
Volume: 59
Issue: 7 Suppl
Pages: 1773s-1777s
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Publication
15565109 | J:95489
First Author: Lee JS
Year: 2004
Journal: Nat Genet
Title: Application of comparative functional genomics to identify best-fit mouse models to study human cancer.
Volume: 36
Issue: 12
Pages: 1306-11
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Publication
34625792 | J:333407
First Author: Pighi C
Year: 2021
Journal: Blood Adv
Title: Frequent mutations of FBXO11 highlight BCL6 as a therapeutic target in Burkitt lymphoma.
Volume: 5
Issue: 23
Pages: 5239-5257
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Publication
18981293 | J:146340
First Author: Young RM
Year: 2009
Journal: Blood
Title: Mouse models of non-Hodgkin lymphoma reveal Syk as an important therapeutic target.
Volume: 113
Issue: 11
Pages: 2508-16
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Publication
35149590 | J:322602
First Author: Fernandez MR
Year: 2022
Journal: Cancer Res
Title: Disrupting the MYC-TFEB Circuit Impairs Amino Acid Homeostasis and Provokes Metabolic Anergy.
Volume: 82
Issue: 7
Pages: 1234-1250
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Publication
35420133 | J:325542
 
First Author: Melendez E
Year: 2022
Journal: Development
Title: Natural killer cells act as an extrinsic barrier for in vivo reprogramming.
Volume: 149
Issue: 8
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Publication
19209230 | J:183308
First Author: Rutishauser D
Year: 2009
Journal: PLoS One
Title: The comprehensive native interactome of a fully functional tagged prion protein.
Volume: 4
Issue: 2
Pages: e4446
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Publication
25069779 | J:210803
First Author: Hollern DP
Year: 2014
Journal: Breast Cancer Res
Title: A genomic analysis of mouse models of breast cancer reveals molecular features of mouse models and relationships to human breast cancer.
Volume: 16
Issue: 3
Pages: R59
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Publication
22438825 | J:183477
First Author: Nilsson LM
Year: 2012
Journal: PLoS Genet
Title: Mouse genetics suggests cell-context dependency for Myc-regulated metabolic enzymes during tumorigenesis.
Volume: 8
Issue: 3
Pages: e1002573
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Publication
21363884 | J:171510
First Author: Fratta P
Year: 2011
Journal: Hum Mol Genet
Title: P0S63del impedes the arrival of wild-type P0 glycoprotein to myelin in CMT1B mice.
Volume: 20
Issue: 11
Pages: 2081-90
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Publication
37767768 | J:350168
First Author: Welsh SJ
Year: 2024
Journal: Blood Cancer Discov
Title: Transcriptional Heterogeneity Overcomes Super-Enhancer Disrupting Drug Combinations in Multiple Myeloma.
Volume: 5
Issue: 1
Pages: 34-55
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Publication
9139821 | J:40055
First Author: Alland L
Year: 1997
Journal: Nature
Title: Role for N-CoR and histone deacetylase in Sin3-mediated transcriptional repression.
Volume: 387
Issue: 6628
Pages: 49-55
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Publication
19029958 | J:143065
First Author: Meyer N
Year: 2008
Journal: Nat Rev Cancer
Title: Reflecting on 25 years with MYC.
Volume: 8
Issue: 12
Pages: 976-90
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Publication
23475876 | J:198393
First Author: Schnepp RW
Year: 2013
Journal: Cancer Discov
Title: Targeting MYCN: a good BET for improving neuroblastoma therapy?
Volume: 3
Issue: 3
Pages: 255-7
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Publication
22672505 | J:201032
First Author: Altman BJ
Year: 2012
Journal: FEBS J
Title: Normal and cancer cell metabolism: lymphocytes and lymphoma.
Volume: 279
Issue: 15
Pages: 2598-609
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Publication
24494196 | J:233236
 
First Author: Case AJ
Year: 2014
Journal: Redox Biol
Title: Absence of manganese superoxide dismutase delays p53-induced tumor formation.
Volume: 2
Pages: 220-3
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Publication
38586957 | J:361164
First Author: Zhu Y
Year: 2024
Journal: Circulation
Title: Asparagine Synthetase Marks a Distinct Dependency Threshold for Cardiomyocyte Dedifferentiation.
Volume: 149
Issue: 23
Pages: 1833-1851
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Allele
Fmn1<ld-TgHD> | MGI:1856291
 
Name: formin 1; limb deformity TgHD
Allele Type: Transgenic
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Publication
11856531 | J:74630
First Author: Magdaleno S
Year: 2002
Journal: Neuron
Title: Rescue of ataxia and preplate splitting by ectopic expression of Reelin in reeler mice.
Volume: 33
Issue: 4
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