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Search results 3101 to 3200 out of 3383 for Pdx1

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Type Details Score
Publication
34345920 | J:339816
 
First Author: Altman MK
Year: 2021
Journal: Development
Title: TRPM7 is a crucial regulator of pancreatic endocrine development and high-fat-diet-induced ?-cell proliferation.
Volume: 148
Issue: 16
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Publication
37098965 | J:337706
First Author: Wan L
Year: 2023
Journal: Cancer Discov
Title: Splicing Factor SRSF1 Promotes Pancreatitis and KRASG12D-Mediated Pancreatic Cancer.
Volume: 13
Issue: 7
Pages: 1678-1695
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Publication
28801621 | J:287496
First Author: Horii T
Year: 2017
Journal: Sci Rep
Title: Efficient generation of conditional knockout mice via sequential introduction of lox sites.
Volume: 7
Issue: 1
Pages: 7891
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Publication
38905124 | J:353482
First Author: Ortiz JA
Year: 2024
Journal: Diabetes
Title: Trefoil Factor 2 Expressed by the Murine Pancreatic Acinar Cells Is Required for the Development of Islets and for ?-Cell Function During Aging.
Volume: 73
Issue: 9
Pages: 1447-1461
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Publication
26512112 | J:227471
First Author: Antonucci L
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: Basal autophagy maintains pancreatic acinar cell homeostasis and protein synthesis and prevents ER stress.
Volume: 112
Issue: 45
Pages: E6166-74
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Publication
31447265 | J:284132
First Author: Murakami S
Year: 2019
Journal: Dev Cell
Title: A Yap-Myc-Sox2-p53 Regulatory Network Dictates Metabolic Homeostasis and Differentiation in Kras-Driven Pancreatic Ductal Adenocarcinomas.
Volume: 51
Issue: 1
Pages: 113-128.e9
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Strain
MGI:5810713 | C57BL/6-Tg(Pdx1-itTA)#Fto/Orl
Attribute String: coisogenic, mutant strain, transgenic
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Genotype
Genotype
Symbol: Myt1/Myt1 Tg(Pdx1-cre)89.1Dam/?
Background: involves: 129 * C57BL/6 * CBA * CD-1 * SJL
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Brca2/Brca2 Kras/Kras<+> Trp53/Trp53<+> Tg(Pdx1-cre)6Tuv/?
Background: involves: 129P2/OlaHsd * 129S/SvEv * 129S4/SvJae * C57BL/6 * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Brca2/Brca2 Kras/Kras<+> Tg(Pdx1-cre)6Tuv/?
Background: involves: 129P2/OlaHsd * 129S/SvEv * 129S4/SvJae * C57BL/6 * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Kras/Kras<+> Pten/Pten<+> Tg(Pdx1-cre)89.1Dam/?
Background: involves: 129S4/SvJae * BALB/c * C57BL/6
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Kras/Kras<+> Pten/Pten Tg(Pdx1-cre)89.1Dam/?
Background: involves: 129S4/SvJae * BALB/c * C57BL/6 * CBA
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Cdkn2a/Cdkn2a<+> Kras/Kras<+> Trp53/Trp53 Tg(Pdx1-cre)89.1Dam/?
Background: involves: 129 * C57BL/6 * CBA * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Cdkn2a/Cdkn2a Kras/Kras<+> Trp53/Trp53 Tg(Pdx1-cre)89.1Dam/?
Background: involves: 129 * C57BL/6 * CBA * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Cdkn2a/Cdkn2a<+> Kras/Kras<+> Trp53/Trp53<+> Tg(Pdx1-cre)89.1Dam/?
Background: involves: 129 * C57BL/6 * CBA * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Cdkn2a/Cdkn2a Kras/Kras<+> Trp53/Trp53<+> Tg(Pdx1-cre)89.1Dam/?
Background: involves: 129 * C57BL/6 * CBA * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Kras/Kras<+> Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Pdx1-cre)6Tuv/? TgTn(sb-T2/Onc)#Dla/?
Background: involves: 129S4/SvJae * 129S6/SvEvTac * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Brca1/Brca1 Kras/Kras<+> Trp53/Trp53 Tg(Pdx1-cre)6Tuv/?
Background: involves: 129S4/SvJae * C57BL/6 * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Brca1/Brca1 Kras/Kras<+> Trp53/Trp53 Tg(Pdx1-cre)6Tuv/?
Background: involves: 129S4/SvJae * C57BL/6 * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(CAG-Bgeo,-tTA,-EGFP)2A11Kuw/? Tg(Pdx1-cre)6Tuv/? Tg(tetO-MYC)36Bop/?
Background: involves: 129P2/OlaHsd * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Cdkn2a/Cdkn2a<+> Tg(CAG-Bgeo,-tTA,-EGFP)2A11Kuw/? Tg(Pdx1-cre)6Tuv/? Tg(tetO-MYC)36Bop/?
Background: involves: 129/Sv * 129P2/OlaHsd * C57BL/6J * FVB/N * SJL
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Cish/Cish Tg(Ins1-EGFP)1Hara/? Tg(Pdx1-cre)89.1Dam/?
Background: involves: C57BL/6 * CBA * CD-1
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Kras/Kras<+> Tg(CAG-Bgeo,-tsA58T)T26Ichi/? Tg(Pdx1-cre)6Tuv/?
Background: involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/? Tg(Pdx1-cre)6Tuv/?
Background: B6.Cg-Gt(ROSA)26Sor Tg(Pdx1-cre)6Tuv
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Kras/Kras<+> Tg(Pdx1-cre)6Tuv/? Trp53/Trp53
Background: involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Kras/Kras<+> Rab11fip1/Rab11fip1 Tg(Pdx1-cre)6Tuv/? Trp53/Trp53<+>
Background: involves: 129S4/SvJae * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Epha2/Epha2 Kras/Kras<+> Trp53/Trp53<+> Tg(Pdx1-cre)6Tuv/?
Background: involves: 129S/SvEv * 129S4/SvJae * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Kras/Kras<+> Prdm1/Prdm1 Tg(Pdx1-cre)6Tuv/? Trp53/Trp53<+>
Background: involves: 129 * C57BL/6NCrl * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Kras/Kras<+> Tg(Pdx1-cre)6Tuv/? Trp53/Trp53<+>
Background: involves: 129 * C57BL/6NCrl * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Cd9/Cd9<+> Kras/Kras<+> Tg(Pdx1-cre)6Tuv/? Trp53/Trp53<+>
Background: involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6N * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Kras/Kras<+> Tg(Pdx1-cre)6Tuv/? Trp53/Trp53<+>
Background: involves: 129P2/OlaHsd * 129S4/SvJae * 129X1/SvJ * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Kras/Kras<+> Tg(Pdx1-cre)6Tuv/? Trp53/Trp53
Background: involves: 129P2/OlaHsd * 129S4/SvJae * 129X1/SvJ * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Cdk8/Cdk8 Tg(Pdx1-cre)6Tuv/?
Background: involves: C57BL/6N * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Kras/Kras<+> Tg(Pdx1-cre)6Tuv/? Trp53/Trp53<+>
Background: involves: 129S4/SvJae * 129S6/SvEvTac * C57BL/6 * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Trim29/Trim29 Tg(Pdx1-cre)6Tuv/?
Background: involves: C57BL/6N * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Pdx1-cre)89.1Dam/? Trim29/Trim29
Background: involves: 129 * C57BL/6 * CBA
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Acaa1a/Acaa1a<+> Kras/Kras<+> Trp53/Trp53<+> Tg(Pdx1-cre)6Tuv/?
Background: involves: 129S4/SvJae * C57BL/6 * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gata4/Gata4 Gata6/Gata6 Tg(Pdx1-cre)6Tuv/?
Background: involves: 129S1/Sv * 129X1/SvJ * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gata4/Gata4<+> Gata6/Gata6<+> Tg(Pdx1-cre)6Tuv/?
Background: involves: 129S1/Sv * 129X1/SvJ * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gata4/Gata4<+> Gata6/Gata6 Tg(Pdx1-cre)6Tuv/?
Background: involves: 129S1/Sv * 129X1/SvJ * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Lats1/Lats1 Lats2/Lats2 Tg(Pdx1-cre)89.1Dam/? Wwtr1/Wwtr1<+> Yap1/Yap1
Background: involves: 129S6/SvEvTac * 129S/SvEv * C57BL/6Brd * CBA * CD-1
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gata4/Gata4 Gata6/Gata6<+> Tg(Pdx1-cre)6Tuv/?
Background: involves: 129S1/Sv * 129X1/SvJ * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Dpy30/Dpy30 Tg(Pdx1-cre)89.1Dam/?
Background: involves: C57BL/6 * C57BL/6N * CBA
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Pdx1-flpo)#Ybi/?
Background: involves: 129S6/SvEvTac
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Myt1/Myt1 Myt1l/Myt1l St18/St18 Tg(Ins1-EGFP)1Hara/? Tg(Pdx1-cre)89.1Dam/?
Background: involves: 129S6/SvEvTac * C57BL/6 * CBA * CD-1
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Ccpg1/Ccpg1 Kras/Kras<+> Tg(Pdx1-cre)6Tuv/?
Background: involves: 129S4/SvJae * C57BL/6N * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Mirc20/Mirc20 Tg(Pdx1-cre)89.1Dam/?
Background: involves: 129 * C57BL/6 * CBA
Zygosity: cn
Has Mutant Allele: true
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Protein
Q9WVH4
Organism: Mus musculus/domesticus
Length: 672  
Fragment?: false
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Protein
A2AWH7
Organism: Mus musculus/domesticus
Length: 218  
Fragment?: true
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Protein
A2AWH8
Organism: Mus musculus/domesticus
Length: 220  
Fragment?: false
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Protein
B1AUT2
Organism: Mus musculus/domesticus
Length: 448  
Fragment?: true
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Protein
H9KUZ0
Organism: Mus musculus/domesticus
Length: 244  
Fragment?: false
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Protein
Q3TZJ4
Organism: Mus musculus/domesticus
Length: 200  
Fragment?: false
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Protein
Q4KL34
Organism: Mus musculus/domesticus
Length: 200  
Fragment?: false
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Publication
33740421 | J:305484
First Author: Su H
Year: 2021
Journal: Cancer Cell
Title: Cancer cells escape autophagy inhibition via NRF2-induced macropinocytosis.
Volume: 39
Issue: 5
Pages: 678-693.e11
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Publication
29249692 | J:253745
First Author: Renz BW
Year: 2018
Journal: Cancer Cell
Title: ?2 Adrenergic-Neurotrophin Feedforward Loop Promotes Pancreatic Cancer.
Volume: 33
Issue: 1
Pages: 75-90.e7
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Publication
42361199 | J:393116
First Author: Schmiechen ZC
Year: 2026
Journal: Sci Immunol
Title: T(reg) cells promote immunotherapy-induced immune evasion by restraining CD4 T cell control of MHC-I-deficient metastatic pancreatic cancer.
Volume: 11
Issue: 120
Pages: eadz4302
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Publication
24097820 | J:205411
First Author: Zhang Y
Year: 2013
Journal: Cancer Res
Title: Interleukin-6 is required for pancreatic cancer progression by promoting MAPK signaling activation and oxidative stress resistance.
Volume: 73
Issue: 20
Pages: 6359-74
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Publication
33307028 | J:308020
First Author: Peran I
Year: 2021
Journal: Gastroenterology
Title: Cadherin 11 Promotes Immunosuppression and Extracellular Matrix Deposition to Support Growth of Pancreatic Tumors and Resistance to Gemcitabine in Mice.
Volume: 160
Issue: 4
Pages: 1359-1372.e13
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Publication
26567136 | J:237566
First Author: Baird JR
Year: 2016
Journal: Cancer Res
Title: Radiotherapy Combined with Novel STING-Targeting Oligonucleotides Results in Regression of Established Tumors.
Volume: 76
Issue: 1
Pages: 50-61
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Publication
39178856 | J:361504
First Author: Alam MS
Year: 2024
Journal: Cell Rep Med
Title: TNFR1 signaling promotes pancreatic tumor growth by limiting dendritic cell number and function.
Volume: 5
Issue: 9
Pages: 101696
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Publication
40825871 | J:374926
First Author: Liu M
Year: 2025
Journal: Nat Genet
Title: Tracing the evolution of single-cell 3D genomes in Kras-driven cancers.
Volume: 57
Issue: 12
Pages: 3075-3087
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Publication
34188043 | J:307917
First Author: Isermann T
Year: 2021
Journal: Nat Commun
Title: Suppression of HSF1 activity by wildtype p53 creates a driving force for p53 loss-of-heterozygosity.
Volume: 12
Issue: 1
Pages: 4019
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Publication
41105672 | J:377428
First Author: Lasse Opsahl EL
Year: 2026
Journal: Cancer Res
Title: Fibroblast STAT3 Activation Drives Organ-Specific Premetastatic Niche Formation.
Volume: 86
Issue: 1
Pages: 22-39
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Publication
29017057 | J:243744
First Author: Mello SS
Year: 2017
Journal: Cancer Cell
Title: A p53 Super-tumor Suppressor Reveals a Tumor Suppressive p53-Ptpn14-Yap Axis in Pancreatic Cancer.
Volume: 32
Issue: 4
Pages: 460-473.e6
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Publication
31116975 | J:284493
First Author: Sharon N
Year: 2019
Journal: Cell Rep
Title: Wnt Signaling Separates the Progenitor and Endocrine Compartments during Pancreas Development.
Volume: 27
Issue: 8
Pages: 2281-2291.e5
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Publication
22699621 | J:186717
First Author: P?rez-Mancera PA
Year: 2012
Journal: Nature
Title: The deubiquitinase USP9X suppresses pancreatic ductal adenocarcinoma.
Volume: 486
Issue: 7402
Pages: 266-70
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Publication
30858608 | J:285667
First Author: Liko D
Year: 2019
Journal: Cell Death Differ
Title: Brf1 loss and not overexpression disrupts tissues homeostasis in the intestine, liver and pancreas.
Volume: 26
Issue: 12
Pages: 2535-2550
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Publication
28790031 | J:245611
First Author: Chiou SH
Year: 2017
Journal: Cancer Discov
Title: BLIMP1 Induces Transient Metastatic Heterogeneity in Pancreatic Cancer.
Volume: 7
Issue: 10
Pages: 1184-1199
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Publication
25024225 | J:212242
First Author: Lee JJ
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Stromal response to Hedgehog signaling restrains pancreatic cancer progression.
Volume: 111
Issue: 30
Pages: E3091-100
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Publication
27088855 | J:372413
First Author: Nielsen SR
Year: 2016
Journal: Nat Cell Biol
Title: Macrophage-secreted granulin supports pancreatic cancer metastasis by inducing liver fibrosis.
Volume: 18
Issue: 5
Pages: 549-60
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Publication
24216479 | J:204180
First Author: Court H
Year: 2013
Journal: J Clin Invest
Title: Isoprenylcysteine carboxylmethyltransferase deficiency exacerbates KRAS-driven pancreatic neoplasia via Notch suppression.
Volume: 123
Issue: 11
Pages: 4681-94
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Publication
23361300 | J:196881
First Author: Khalaileh A
Year: 2013
Journal: Cancer Res
Title: Phosphorylation of ribosomal protein S6 attenuates DNA damage and tumor suppression during development of pancreatic cancer.
Volume: 73
Issue: 6
Pages: 1811-20
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Publication
25127677 | J:314626
First Author: Hermann PC
Year: 2014
Journal: Gastroenterology
Title: Nicotine promotes initiation and progression of KRAS-induced pancreatic cancer via Gata6-dependent dedifferentiation of acinar cells in mice.
Volume: 147
Issue: 5
Pages: 1119-33.e4
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Publication
35120601 | J:320538
First Author: Alam A
Year: 2022
Journal: Cancer Cell
Title: Fungal mycobiome drives IL-33 secretion and type 2 immunity in pancreatic cancer.
Volume: 40
Issue: 2
Pages: 153-167.e11
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Publication
30228296 | J:283080
First Author: Chiou SH
Year: 2018
Journal: Sci Rep
Title: Hmga2 is dispensable for pancreatic cancer development, metastasis, and therapy resistance.
Volume: 8
Issue: 1
Pages: 14008
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Publication
32234521 | J:336882
First Author: Ruscetti M
Year: 2020
Journal: Cell
Title: Senescence-Induced Vascular Remodeling Creates Therapeutic Vulnerabilities in Pancreas Cancer.
Volume: 181
Issue: 2
Pages: 424-441.e21
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Publication
34907344 | J:321218
First Author: Klimovich B
Year: 2022
Journal: Oncogene
Title: p53 partial loss-of-function mutations sensitize to chemotherapy.
Volume: 41
Issue: 7
Pages: 1011-1023
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Publication
25119024 | J:217085
First Author: Viale A
Year: 2014
Journal: Nature
Title: Oncogene ablation-resistant pancreatic cancer cells depend on mitochondrial function.
Volume: 514
Issue: 7524
Pages: 628-32
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Publication
29364867 | J:257934
First Author: Mueller S
Year: 2018
Journal: Nature
Title: Evolutionary routes and KRAS dosage define pancreatic cancer phenotypes.
Volume: 554
Issue: 7690
Pages: 62-68
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Publication
31983610 | J:285699
First Author: Cheung EC
Year: 2020
Journal: Cancer Cell
Title: Dynamic ROS Control by TIGAR Regulates the Initiation and Progression of Pancreatic Cancer.
Volume: 37
Issue: 2
Pages: 168-182.e4
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Publication
33839689 | J:308176
First Author: Kim MP
Year: 2021
Journal: Cancer Discov
Title: Oncogenic KRAS Recruits an Expansive Transcriptional Network through Mutant p53 to Drive Pancreatic Cancer Metastasis.
Volume: 11
Issue: 8
Pages: 2094-2111
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Publication
32442403 | J:290368
First Author: Wang Z
Year: 2020
Journal: Cancer Cell
Title: SETD5-Coordinated Chromatin Reprogramming Regulates Adaptive Resistance to Targeted Pancreatic Cancer Therapy.
Volume: 37
Issue: 6
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