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Search results 3201 to 3295 out of 3295 for Kras

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Type Details Score
Publication
First Author: Ben C
Year: 2020
Journal: J Biol Chem
Title: Alternative splicing reverses the cell-intrinsic and cell-extrinsic pro-oncogenic potentials of YAP1.
Volume: 295
Issue: 41
Pages: 13965-13980
Publication
First Author: Assenat E
Year: 2021
Journal: Int J Cancer
Title: Phase II study evaluating the association of gemcitabine, trastuzumab and erlotinib as first-line treatment in patients with metastatic pancreatic adenocarcinoma (GATE 1).
Volume: 148
Issue: 3
Pages: 682-691
Publication
First Author: Tovell H
Year: 2021
Journal: Biochem J
Title: PHLPPing the balance: restoration of protein kinase C in cancer.
Volume: 478
Issue: 2
Pages: 341-355
Publication
First Author: Knight JRP
Year: 2021
Journal: Cancer Discov
Title: MNK Inhibition Sensitizes KRAS-Mutant Colorectal Cancer to mTORC1 Inhibition by Reducing eIF4E Phosphorylation and c-MYC Expression.
Volume: 11
Issue: 5
Pages: 1228-1247
Publication
First Author: Alonso-Curbelo D
Year: 2021
Journal: Nature
Title: A gene-environment-induced epigenetic program initiates tumorigenesis.
Volume: 590
Issue: 7847
Pages: 642-648
Publication
First Author: Rangel DF
Year: 2021
Journal: Oncogene
Title: Endoplasmic reticulum chaperone GRP78/BiP is critical for mutant Kras-driven lung tumorigenesis.
Volume: 40
Issue: 20
Pages: 3624-3632
Publication
First Author: Aney KJ
Year: 2021
Journal: J Pathol
Title: More than acinar identity? A novel cystic phenotype suggests broader roles for NR5A2 in pancreatic cancer†.
Volume: 254
Issue: 1
Pages: 1-4
Publication
First Author: Ye J
Year: 2020
Journal: Cell Death Dis
Title: PRDM3 attenuates pancreatitis and pancreatic tumorigenesis by regulating inflammatory response.
Volume: 11
Issue: 3
Pages: 187
Publication
First Author: Gagné-Sansfaçon J
Year: 2016
Journal: Oncotarget
Title: SHP-2 phosphatase contributes to KRAS-driven intestinal oncogenesis but prevents colitis-associated cancer development.
Volume: 7
Issue: 40
Pages: 65676-65695
Publication  
First Author: Schofield HK
Year: 2018
Journal: JCI Insight
Title: Mutant p53R270H drives altered metabolism and increased invasion in pancreatic ductal adenocarcinoma.
Volume: 3
Issue: 2
Publication
First Author: Ji P
Year: 2016
Journal: Oncotarget
Title: Driver or passenger effects of augmented c-Myc and Cdc20 in gliomagenesis.
Volume: 7
Issue: 17
Pages: 23521-9
Publication  
First Author: Yan HH
Year: 2021
Journal: Cancer Lett
Title: ANGPTL4 accelerates KRASG12D-Induced acinar to ductal metaplasia and pancreatic carcinogenesis.
Volume: 519
Pages: 185-198
Publication
First Author: Ge W
Year: 2022
Journal: Gastroenterology
Title: miR-802 Suppresses Acinar-to-Ductal Reprogramming During Early Pancreatitis and Pancreatic Carcinogenesis.
Volume: 162
Issue: 1
Pages: 269-284
Publication  
First Author: de Latouliere L
Year: 2016
Journal: Ann Anat
Title: A bioluminescent mouse model of proliferation to highlight early stages of pancreatic cancer: A suitable tool for preclinical studies.
Volume: 207
Pages: 2-8
Publication      
First Author: Falcomatà C
Year: 2021
Journal: Cancer Discov
Title: Genetic Screens Identify a Context-Specific PI3K/p27Kip1 Node Driving Extrahepatic Biliary Cancer.
Publication
First Author: Sano M
Year: 2016
Journal: Neoplasia
Title: Activation of WNT/β-Catenin Signaling Enhances Pancreatic Cancer Development and the Malignant Potential Via Up-regulation of Cyr61.
Volume: 18
Issue: 12
Pages: 785-794
Publication
First Author: Chen Z
Year: 2020
Journal: Theranostics
Title: Inactivation of tumor suppressor gene Clusterin leads to hyperactivation of TAK1-NF-κB signaling axis in lung cancer cells and denotes a therapeutic opportunity.
Volume: 10
Issue: 25
Pages: 11520-11534
Publication
First Author: Mathew E
Year: 2014
Journal: J Biol Chem
Title: The transcription factor GLI1 modulates the inflammatory response during pancreatic tissue remodeling.
Volume: 289
Issue: 40
Pages: 27727-43
Publication
First Author: Hoffman MT
Year: 2021
Journal: Cell Mol Gastroenterol Hepatol
Title: The Gustatory Sensory G-Protein GNAT3 Suppresses Pancreatic Cancer Progression in Mice.
Volume: 11
Issue: 2
Pages: 349-369
Publication
First Author: Capaccione KM
Year: 2014
Journal: Oncotarget
Title: Sox9 mediates Notch1-induced mesenchymal features in lung adenocarcinoma.
Volume: 5
Issue: 11
Pages: 3636-50
Publication
First Author: Osswald L
Year: 2021
Journal: Mol Cancer Res
Title: Oncogenic KrasG12D Activation in the Nonhematopoietic Bone Marrow Microenvironment Causes Myelodysplastic Syndrome in Mice.
Volume: 19
Issue: 9
Pages: 1596-1608
Publication
First Author: Chao T
Year: 2016
Journal: Cancer Immunol Res
Title: CXCR2-Dependent Accumulation of Tumor-Associated Neutrophils Regulates T-cell Immunity in Pancreatic Ductal Adenocarcinoma.
Volume: 4
Issue: 11
Pages: 968-982
Publication
First Author: Tao S
Year: 2018
Journal: Mol Carcinog
Title: The effects of NRF2 modulation on the initiation and progression of chemically and genetically induced lung cancer.
Volume: 57
Issue: 2
Pages: 182-192
Publication  
First Author: Xu Q
Year: 2022
Journal: Proc Natl Acad Sci U S A
Title: Loss of TET reprograms Wnt signaling through impaired demethylation to promote lung cancer development.
Volume: 119
Issue: 6
Publication
First Author: Zhao M
Year: 2018
Journal: Int J Biol Sci
Title: The role of TGF-β/SMAD4 signaling in cancer.
Volume: 14
Issue: 2
Pages: 111-123
Publication
First Author: Malkoski SP
Year: 2014
Journal: Mol Carcinog
Title: Role of PTEN in basal cell derived lung carcinogenesis.
Volume: 53
Issue: 10
Pages: 841-6
Publication
First Author: Pirazzoli V
Year: 2016
Journal: Clin Cancer Res
Title: Afatinib plus Cetuximab Delays Resistance Compared to Single-Agent Erlotinib or Afatinib in Mouse Models of TKI-Naïve EGFR L858R-Induced Lung Adenocarcinoma.
Volume: 22
Issue: 2
Pages: 426-35
Publication
First Author: Xue B
Year: 2021
Journal: Genes Dev
Title: miR-200 deficiency promotes lung cancer metastasis by activating Notch signaling in cancer-associated fibroblasts.
Volume: 35
Issue: 15-16
Pages: 1109-1122
Publication  
First Author: Janardhan HP
Year: 2022
Journal: JCI Insight
Title: Pathological MAPK activation-mediated lymphatic basement membrane disruption causes lymphangiectasia that is treatable with ravoxertinib.
Volume: 7
Issue: 17
Publication
First Author: Kim M
Year: 2022
Journal: Mol Cancer Res
Title: Caspase 9b Drives Cellular Transformation, Lung Inflammation, and Lung Tumorigenesis.
Volume: 20
Issue: 8
Pages: 1284-1294
Publication
First Author: Boumelha J
Year: 2022
Journal: Cancer Res
Title: An Immunogenic Model of KRAS-Mutant Lung Cancer Enables Evaluation of Targeted Therapy and Immunotherapy Combinations.
Volume: 82
Issue: 19
Pages: 3435-3448
Publication
First Author: Cronin SJF
Year: 2022
Journal: Sci Transl Med
Title: Phenotypic drug screen uncovers the metabolic GCH1/BH4 pathway as key regulator of EGFR/KRAS-mediated neuropathic pain and lung cancer.
Volume: 14
Issue: 660
Pages: eabj1531
Publication    
First Author: Yang K
Year: 2023
Journal: Cell Death Differ
Title: Long non-coding RNA HIF1A-As2 and MYC form a double-positive feedback loop to promote cell proliferation and metastasis in KRAS-driven non-small cell lung cancer.
Pages: 1-17
Publication
First Author: Hill W
Year: 2023
Journal: Nature
Title: Lung adenocarcinoma promotion by air pollutants.
Volume: 616
Issue: 7955
Pages: 159-167
Publication
First Author: Lee MS
Year: 2023
Journal: Nature
Title: Ornithine aminotransferase supports polyamine synthesis in pancreatic cancer.
Volume: 616
Issue: 7956
Pages: 339-347
Publication
First Author: Kaiser AM
Year: 2023
Journal: Nature
Title: p53 governs an AT1 differentiation programme in lung cancer suppression.
Volume: 619
Issue: 7971
Pages: 851-859
Publication
First Author: Juul NH
Year: 2023
Journal: Nature
Title: KRAS(G12D) drives lepidic adenocarcinoma through stem-cell reprogramming.
Volume: 619
Issue: 7971
Pages: 860-867
Publication
First Author: Li J
Year: 2023
Journal: Nature
Title: Histone demethylase KDM5D upregulation drives sex differences in colon cancer.
Volume: 619
Issue: 7970
Pages: 632-639
Publication
First Author: Larrue R
Year: 2023
Journal: Cell Death Dis
Title: miR-92a-3p regulates cisplatin-induced cancer cell death.
Volume: 14
Issue: 9
Pages: 603
Publication  
First Author: Konen JM
Year: 2023
Journal: J Clin Invest
Title: Autotaxin suppresses cytotoxic T cells via LPAR5 to promote anti-PD-1 resistance in non-small cell lung cancer.
Volume: 133
Issue: 17
Publication
First Author: Mello SS
Year: 2023
Journal: Proc Natl Acad Sci U S A
Title: Multifaceted role for p53 in pancreatic cancer suppression.
Volume: 120
Issue: 10
Pages: e2211937120
Publication  
First Author: Sánchez-Tilló E
Year: 2023
Journal: JCI Insight
Title: The EMT factor ZEB1 paradoxically inhibits EMT in BRAF-mutant carcinomas.
Volume: 8
Issue: 20
Publication
First Author: Li J
Year: 2023
Journal: Sci Transl Med
Title: Tumor-specific GPX4 degradation enhances ferroptosis-initiated antitumor immune response in mouse models of pancreatic cancer.
Volume: 15
Issue: 720
Pages: eadg3049
Publication
First Author: Mukhopadhyay S
Year: 2023
Journal: Cancer Res
Title: Genome-Wide CRISPR Screens Identify Multiple Synthetic Lethal Targets That Enhance KRASG12C Inhibitor Efficacy.
Volume: 83
Issue: 24
Pages: 4095-4111
Publication
First Author: Li J
Year: 2023
Journal: Proc Natl Acad Sci U S A
Title: Oncogenic dependency plays a dominant role in the immune response to cancer.
Volume: 120
Issue: 41
Pages: e2308635120
Publication
First Author: Alanazi M
Year: 2024
Journal: Cancer Sci
Title: Cytosolic DNA sensor AIM2 promotes KRAS-driven lung cancer independent of inflammasomes.
Volume: 115
Issue: 6
Pages: 1834-1850
Publication
First Author: Pozzato C
Year: 2024
Journal: EMBO Mol Med
Title: ERK5 suppression overcomes FAK inhibitor resistance in mutant KRAS-driven non-small cell lung cancer.
Volume: 16
Issue: 10
Pages: 2402-2426
Publication
First Author: Zuidema A
Year: 2024
Journal: Sci Rep
Title: Colorectal carcinoma progression is not influenced by the pseudokinase PEAK1.
Volume: 14
Issue: 1
Pages: 27663
Publication
First Author: Tinsley SL
Year: 2024
Journal: Oncogene
Title: KRAS-mediated upregulation of CIP2A promotes suppression of PP2A-B56α to initiate pancreatic cancer development.
Volume: 43
Issue: 50
Pages: 3673-3687
Publication
First Author: Benitz S
Year: 2024
Journal: Cancer Discov
Title: ROR2 Regulates Cellular Plasticity in Pancreatic Neoplasia and Adenocarcinoma.
Volume: 14
Issue: 11
Pages: 2162-2182
Publication
First Author: Lin Y
Year: 2024
Journal: Gut
Title: Pancreatic STAT5 activation promotes Kras(G12D)-induced and inflammation-induced acinar-to-ductal metaplasia and pancreatic cancer.
Volume: 73
Issue: 11
Pages: 1831-1843
Publication
First Author: Chung WC
Year: 2025
Journal: Oncogene
Title: Lfng-expressing centroacinar cell is a unique cell-of-origin for p53 deficient pancreatic cancer.
Volume: 44
Issue: 6
Pages: 348-362
Publication  
First Author: Lasse-Opsahl EL
Year: 2025
Journal: JCI Insight
Title: KRASG12D drives immunosuppression in lung adenocarcinoma through paracrine signaling.
Volume: 10
Issue: 1
Publication
First Author: Fuentes-Mateos R
Year: 2019
Journal: Cell Death Dis
Title: Concomitant deletion of HRAS and NRAS leads to pulmonary immaturity, respiratory failure and neonatal death in mice.
Volume: 10
Issue: 11
Pages: 838
Publication
First Author: Ideno N
Year: 2019
Journal: Lab Invest
Title: A pipeline for rapidly generating genetically engineered mouse models of pancreatic cancer using in vivo CRISPR-Cas9-mediated somatic recombination.
Volume: 99
Issue: 8
Pages: 1233-1244
Publication
First Author: Wittenberg AD
Year: 2016
Journal: PLoS One
Title: Phosphorylated Ribosomal Protein S6 Is Required for Akt-Driven Hyperplasia and Malignant Transformation, but Not for Hypertrophy, Aneuploidy and Hyperfunction of Pancreatic β-Cells.
Volume: 11
Issue: 2
Pages: e0149995
Publication
First Author: Ramdzan ZM
Year: 2014
Journal: PLoS Biol
Title: RAS transformation requires CUX1-dependent repair of oxidative DNA damage.
Volume: 12
Issue: 3
Pages: e1001807
Publication
First Author: Vandal G
Year: 2014
Journal: PLoS One
Title: Ras effector mutant expression suggest a negative regulator inhibits lung tumor formation.
Volume: 9
Issue: 1
Pages: e84745
Publication
First Author: Shields MA
Year: 2013
Journal: Mol Cancer Res
Title: Snail cooperates with KrasG12D to promote pancreatic fibrosis.
Volume: 11
Issue: 9
Pages: 1078-87
Publication
First Author: Bongers G
Year: 2012
Journal: Gastroenterology
Title: A role for the epidermal growth factor receptor signaling in development of intestinal serrated polyps in mice and humans.
Volume: 143
Issue: 3
Pages: 730-740
Publication
First Author: Kim S
Year: 2008
Journal: Cancer Res
Title: Systemic blockade of transforming growth factor-beta signaling augments the efficacy of immunogene therapy.
Volume: 68
Issue: 24
Pages: 10247-56
Publication
First Author: Husain K
Year: 2013
Journal: Carcinogenesis
Title: Prolonged survival and delayed progression of pancreatic intraepithelial neoplasia in LSL-KrasG12D/+;Pdx-1-Cre mice by vitamin E δ-tocotrienol.
Volume: 34
Issue: 4
Pages: 858-63
Publication
First Author: Li S
Year: 2018
Journal: Clin Cancer Res
Title: Assessing Therapeutic Efficacy of MEK Inhibition in a KRASG12C-Driven Mouse Model of Lung Cancer.
Volume: 24
Issue: 19
Pages: 4854-4864
Publication
First Author: Li C
Year: 2021
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Epithelial cell transforming 2 is regulated by Yes-associated protein 1 and mediates pancreatic cancer progression and metastasis.
Volume: 320
Issue: 3
Pages: G380-G395
Publication
First Author: Cook DR
Year: 2022
Journal: Cancer Res
Title: Aberrant Expression and Subcellular Localization of ECT2 Drives Colorectal Cancer Progression and Growth.
Volume: 82
Issue: 1
Pages: 90-104
Publication
First Author: Chen NM
Year: 2017
Journal: Gastroenterology
Title: Context-Dependent Epigenetic Regulation of Nuclear Factor of Activated T Cells 1 in Pancreatic Plasticity.
Volume: 152
Issue: 6
Pages: 1507-1520.e15
Publication
First Author: Chen NM
Year: 2015
Journal: Gastroenterology
Title: NFATc1 Links EGFR Signaling to Induction of Sox9 Transcription and Acinar-Ductal Transdifferentiation in the Pancreas.
Volume: 148
Issue: 5
Pages: 1024-1034.e9
Publication
First Author: Guo Y
Year: 2013
Journal: J Nucl Med
Title: The role of p53 in combination radioimmunotherapy with 64Cu-DOTA-cetuximab and cisplatin in a mouse model of colorectal cancer.
Volume: 54
Issue: 9
Pages: 1621-9
Publication
First Author: Kundu ST
Year: 2022
Journal: Genes Dev
Title: The microRNA-183/96/182 cluster inhibits lung cancer progression and metastasis by inducing an interleukin-2-mediated antitumor CD8+ cytotoxic T-cell response.
Volume: 36
Issue: 9-10
Pages: 582-600
Publication  
First Author: Zhu L
Year: 2022
Journal: Cancers (Basel)
Title: Differential Effects of Dietary Macronutrients on the Development of Oncogenic KRAS-Mediated Pancreatic Ductal Adenocarcinoma.
Volume: 14
Issue: 11
Publication
First Author: Müller F
Year: 2023
Journal: Cell Death Differ
Title: Elevated FSP1 protects KRAS-mutated cells from ferroptosis during tumor initiation.
Volume: 30
Issue: 2
Pages: 442-456
Publication
First Author: Wang Y
Year: 2023
Journal: Cancer Res
Title: Biallelic Dicer1 Mutations in the Gynecologic Tract of Mice Drive Lineage-Specific Development of DICER1 Syndrome-Associated Cancer.
Volume: 83
Issue: 21
Pages: 3517-3528
Publication
First Author: Akbay EA
Year: 2017
Journal: J Thorac Oncol
Title: Interleukin-17A Promotes Lung Tumor Progression through Neutrophil Attraction to Tumor Sites and Mediating Resistance to PD-1 Blockade.
Volume: 12
Issue: 8
Pages: 1268-1279
Publication
First Author: Andries V
Year: 2019
Journal: BMC Cancer
Title: A new mouse model to study the role of ectopic Nanos3 expression in cancer.
Volume: 19
Issue: 1
Pages: 598
Publication
First Author: Ellenson LH
Year: 2005
Journal: Int J Gynecol Cancer
Title: Early molecular changes in endometrial cancer.
Volume: 15
Issue: 2
Pages: 399-400 (Abstr.)
Publication
First Author: Wong CC
Year: 2020
Journal: Gastroenterology
Title: In Colorectal Cancer Cells With Mutant KRAS, SLC25A22-Mediated Glutaminolysis Reduces DNA Demethylation to Increase WNT Signaling, Stemness, and Drug Resistance.
Volume: 159
Issue: 6
Pages: 2163-2180.e6
Publication
First Author: Bailis W
Year: 2019
Journal: Nature
Title: Distinct modes of mitochondrial metabolism uncouple T cell differentiation and function.
Volume: 571
Issue: 7765
Pages: 403-407
Publication
First Author: Watters JW
Year: 2001
Journal: Genomics
Title: Genetic, physical, and transcript map of the Ltxs1 region of mouse chromosome 11.
Volume: 73
Issue: 2
Pages: 223-31
Publication
First Author: Da Cruz S
Year: 2003
Journal: J Biol Chem
Title: Proteomic analysis of the mouse liver mitochondrial inner membrane.
Volume: 278
Issue: 42
Pages: 41566-71
Publication
First Author: Gerhard DS
Year: 2004
Journal: Genome Res
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Volume: 14
Issue: 10B
Pages: 2121-7
Publication
First Author: Huttlin EL
Year: 2010
Journal: Cell
Title: A tissue-specific atlas of mouse protein phosphorylation and expression.
Volume: 143
Issue: 7
Pages: 1174-89
Publication
First Author: Church DM
Year: 2009
Journal: PLoS Biol
Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.
Volume: 7
Issue: 5
Pages: e1000112
Publication
First Author: Mootha VK
Year: 2003
Journal: Cell
Title: Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria.
Volume: 115
Issue: 5
Pages: 629-40
Publication
First Author: Pagliarini DJ
Year: 2008
Journal: Cell
Title: A mitochondrial protein compendium elucidates complex I disease biology.
Volume: 134
Issue: 1
Pages: 112-23
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: RIKEN Data Curation in Mouse Genome Informatics
Publication      
First Author: MGI and IMPC
Year: 2018
Journal: Database Release
Title: MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
Publication        
First Author: The Gene Ontology Consortium
Year: 2016
Title: Automatic assignment of GO terms using logical inference, based on on inter-ontology links
Publication
First Author: Visel A
Year: 2004
Journal: Nucleic Acids Res
Title: GenePaint.org: an atlas of gene expression patterns in the mouse embryo.
Volume: 32
Issue: Database issue
Pages: D552-6
Publication      
First Author: Velocigene
Year: 2008
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals)
Publication      
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
Publication      
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
Publication
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes