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Search results 3201 to 3300 out of 4141 for Mtor

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Type Details Score
Publication
23493289 | J:218879
First Author: Li W
Year: 2013
Journal: Arterioscler Thromb Vasc Biol
Title: Rapamycin inhibits smooth muscle cell proliferation and obstructive arteriopathy attributable to elastin deficiency.
Volume: 33
Issue: 5
Pages: 1028-35
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Publication
30768374 | J:292326
First Author: Wang W
Year: 2019
Journal: FASEB J
Title: Aquaporin-3 deficiency slows cyst enlargement in experimental mouse models of autosomal dominant polycystic kidney disease.
Volume: 33
Issue: 5
Pages: 6185-6196
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Publication
18483250 | J:135023
First Author: Moore T
Year: 2008
Journal: Cancer Res
Title: Reduced susceptibility to two-stage skin carcinogenesis in mice with low circulating insulin-like growth factor I levels.
Volume: 68
Issue: 10
Pages: 3680-8
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Publication
26403076 | J:242957
First Author: Kazdoba TM
Year: 2016
Journal: Genes Brain Behav
Title: Behavioral phenotypes of genetic mouse models of autism.
Volume: 15
Issue: 1
Pages: 7-26
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Publication
22836754 | J:191327
First Author: Wang J
Year: 2012
Journal: Cancer Res
Title: B-Raf activation cooperates with PTEN loss to drive c-Myc expression in advanced prostate cancer.
Volume: 72
Issue: 18
Pages: 4765-76
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Publication
34547769 | J:323302
First Author: Abbonante V
Year: 2021
Journal: Blood Adv
Title: Ablation of collagen VI leads to the release of platelets with altered function.
Volume: 5
Issue: 23
Pages: 5150-5163
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Publication
21737790 | J:186597
First Author: Zhai P
Year: 2011
Journal: Circ Res
Title: Differential roles of GSK-3β during myocardial ischemia and ischemia/reperfusion.
Volume: 109
Issue: 5
Pages: 502-11
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Publication
26033700 | J:345741
First Author: Abdalla M
Year: 2015
Journal: Br J Pharmacol
Title: The Akt inhibitor, triciribine, ameliorates chronic hypoxia-induced vascular pruning and TGFβ-induced pulmonary fibrosis.
Volume: 172
Issue: 16
Pages: 4173-88
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Publication
22056987 | J:179396
First Author: Sun F
Year: 2011
Journal: Nature
Title: Sustained axon regeneration induced by co-deletion of PTEN and SOCS3.
Volume: 480
Issue: 7377
Pages: 372-5
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Publication
17967941 | J:130295
First Author: Zeiser R
Year: 2008
Journal: Blood
Title: Differential impact of mammalian target of rapamycin inhibition on CD4+CD25+Foxp3+ regulatory T cells compared with conventional CD4+ T cells.
Volume: 111
Issue: 1
Pages: 453-62
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Publication
38383802 | J:360913
First Author: Krauter D
Year: 2024
Journal: EMBO Mol Med
Title: Targeting PI3K/Akt/mTOR signaling in rodent models of PMP22 gene-dosage diseases.
Volume: 16
Issue: 3
Pages: 616-640
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Publication
28319045 | J:243606
First Author: Li N
Year: 2017
Journal: J Clin Invest
Title: AKT-mediated stabilization of histone methyltransferase WHSC1 promotes prostate cancer metastasis.
Volume: 127
Issue: 4
Pages: 1284-1302
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Publication
30201609 | J:272814
First Author: Moloughney JG
Year: 2018
Journal: J Biol Chem
Title: mTORC2 modulates the amplitude and duration of GFAT1 Ser-243 phosphorylation to maintain flux through the hexosamine pathway during starvation.
Volume: 293
Issue: 42
Pages: 16464-16478
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Publication
23136410 | J:192244
First Author: McMahon J
Year: 2012
Journal: J Neurosci
Title: Impaired autophagy in neurons after disinhibition of mammalian target of rapamycin and its contribution to epileptogenesis.
Volume: 32
Issue: 45
Pages: 15704-14
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Publication
26577921 | J:301636
First Author: Hsieh AC
Year: 2015
Journal: Sci Signal
Title: Cell type-specific abundance of 4EBP1 primes prostate cancer sensitivity or resistance to PI3K pathway inhibitors.
Volume: 8
Issue: 403
Pages: ra116
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Publication
32084268 | J:288888
First Author: Kole C
Year: 2020
Journal: Invest Ophthalmol Vis Sci
Title: Activating Transcription Factor 3 (ATF3) Protects Retinal Ganglion Cells and Promotes Functional Preservation After Optic Nerve Crush.
Volume: 61
Issue: 2
Pages: 31
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Publication
27597527 | J:259321
 
First Author: LaSarge CL
Year: 2016
Journal: Neurobiol Dis
Title: Disrupted hippocampal network physiology following PTEN deletion from newborn dentate granule cells.
Volume: 96
Pages: 105-114
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Publication
36759189 | J:350824
 
First Author: Dusing M
Year: 2023
Journal: eNeuro
Title: Neurovascular Development in Pten and Tsc2 Mouse Mutants.
Volume: 10
Issue: 2
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Publication
22815528 | J:191334
First Author: Floc'h N
Year: 2012
Journal: Cancer Res
Title: Dual targeting of the Akt/mTOR signaling pathway inhibits castration-resistant prostate cancer in a genetically engineered mouse model.
Volume: 72
Issue: 17
Pages: 4483-93
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Publication
25600212 | J:219722
 
First Author: LaSarge CL
Year: 2015
Journal: Neurobiol Dis
Title: PTEN deletion from adult-generated dentate granule cells disrupts granule cell mossy fiber axon structure.
Volume: 75
Pages: 142-50
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Publication
21493594 | J:170965
First Author: Ellwood-Yen K
Year: 2011
Journal: Cancer Res
Title: PDK1 attenuation fails to prevent tumor formation in PTEN-deficient transgenic mouse models.
Volume: 71
Issue: 8
Pages: 3052-65
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Publication
29389670 | J:263614
First Author: Zordan P
Year: 2018
Journal: J Clin Invest
Title: Tuberous sclerosis complex-associated CNS abnormalities depend on hyperactivation of mTORC1 and Akt.
Volume: 128
Issue: 4
Pages: 1688-1706
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Publication
27371614 | J:249850
First Author: Overall SA
Year: 2016
Journal: Int Immunol
Title: Rapamycin results in Bim-mediated loss of thymic regulatory T cells during development in organ culture.
Volume: 28
Issue: 10
Pages: 513-518
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Publication
24558360 | J:213353
First Author: Yang EJ
Year: 2014
Journal: PLoS One
Title: EGCG attenuates autoimmune arthritis by inhibition of STAT3 and HIF-1α with Th17/Treg control.
Volume: 9
Issue: 2
Pages: e86062
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Publication
26740601 | J:249608
First Author: Stamateris RE
Year: 2016
Journal: Diabetes
Title: Glucose Induces Mouse β-Cell Proliferation via IRS2, MTOR, and Cyclin D2 but Not the Insulin Receptor.
Volume: 65
Issue: 4
Pages: 981-95
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Publication
17110454 | J:145356
First Author: Weyrich AS
Year: 2007
Journal: Blood
Title: mTOR-dependent synthesis of Bcl-3 controls the retraction of fibrin clots by activated human platelets.
Volume: 109
Issue: 5
Pages: 1975-83
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Publication
21633171 | J:175661
First Author: Espeillac C
Year: 2011
Journal: J Clin Invest
Title: S6 kinase 1 is required for rapamycin-sensitive liver proliferation after mouse hepatectomy.
Volume: 121
Issue: 7
Pages: 2821-32
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Publication
22678916 | J:187755
First Author: Chang X
Year: 2012
Journal: Eur J Immunol
Title: Sin1 regulates Treg-cell development but is not required for T-cell growth and proliferation.
Volume: 42
Issue: 6
Pages: 1639-47
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Publication
24126911 | J:204975
First Author: Rastogi R
Year: 2013
Journal: J Biol Chem
Title: Rapamycin induces mitogen-activated protein (MAP) kinase phosphatase-1 (MKP-1) expression through activation of protein kinase B and mitogen-activated protein kinase kinase pathways.
Volume: 288
Issue: 47
Pages: 33966-77
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Publication
31189531 | J:278958
First Author: Gu Z
Year: 2019
Journal: Cancer Discov
Title: Loss of EZH2 Reprograms BCAA Metabolism to Drive Leukemic Transformation.
Volume: 9
Issue: 9
Pages: 1228-1247
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Publication
21124450 | J:165090
First Author: Nakada D
Year: 2010
Journal: Nature
Title: Lkb1 regulates cell cycle and energy metabolism in haematopoietic stem cells.
Volume: 468
Issue: 7324
Pages: 653-8
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Publication
28129027 | J:274386
First Author: Kissing S
Year: 2017
Journal: Autophagy
Title: Disruption of the vacuolar-type H+-ATPase complex in liver causes MTORC1-independent accumulation of autophagic vacuoles and lysosomes.
Volume: 13
Issue: 4
Pages: 670-685
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Publication
22279055 | J:182535
First Author: Golan K
Year: 2012
Journal: Blood
Title: S1P promotes murine progenitor cell egress and mobilization via S1P1-mediated ROS signaling and SDF-1 release.
Volume: 119
Issue: 11
Pages: 2478-88
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Publication
26019175 | J:223927
First Author: Iwayama T
Year: 2015
Journal: Genes Dev
Title: PDGFRα signaling drives adipose tissue fibrosis by targeting progenitor cell plasticity.
Volume: 29
Issue: 11
Pages: 1106-19
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Publication
30910747 | J:278137
 
First Author: Chang H
Year: 2019
Journal: Neurobiol Dis
Title: Seipin deletion in mice enhances phosphorylation and aggregation of tau protein through reduced neuronal PPARγ and insulin resistance.
Volume: 127
Pages: 350-361
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Publication
34899181 | J:351441
 
First Author: Roy A
Year: 2021
Journal: Front Mol Neurosci
Title: Non-synaptic Cell-Autonomous Mechanisms Underlie Neuronal Hyperactivity in a Genetic Model of PIK3CA-Driven Intractable Epilepsy.
Volume: 14
Pages: 772847
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Publication
24295634 | J:207923
 
First Author: Ramamurthy S
Year: 2014
Journal: Neuroscience
Title: AMPK activation regulates neuronal structure in developing hippocampal neurons.
Volume: 259
Pages: 13-24
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Publication
21890496 | J:234598
First Author: Anderl S
Year: 2011
Journal: Hum Mol Genet
Title: Therapeutic value of prenatal rapamycin treatment in a mouse brain model of tuberous sclerosis complex.
Volume: 20
Issue: 23
Pages: 4597-604
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Publication
34571934 | J:311506
 
First Author: Peng Y
Year: 2021
Journal: Cells
Title: Substrate Reduction Therapy Reverses Mitochondrial, mTOR, and Autophagy Alterations in a Cell Model of Gaucher Disease.
Volume: 10
Issue: 9
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Publication
32920594 | J:340198
First Author: Ma X
Year: 2020
Journal: Cell Death Dis
Title: Persistent Rheb-induced mTORC1 activation in spinal cord neurons induces hypersensitivity in neuropathic pain.
Volume: 11
Issue: 9
Pages: 747
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Publication
20068134 | J:164338
First Author: Reed AS
Year: 2010
Journal: Diabetes
Title: Functional role of suppressor of cytokine signaling 3 upregulation in hypothalamic leptin resistance and long-term energy homeostasis.
Volume: 59
Issue: 4
Pages: 894-906
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Publication
28244683 | J:265516
First Author: Li A
Year: 2017
Journal: J Cell Mol Med
Title: Rapamycin treatment dose-dependently improves the cystic kidney in a new ADPKD mouse model via the mTORC1 and cell-cycle-associated CDK1/cyclin axis.
Volume: 21
Issue: 8
Pages: 1619-1635
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Publication
21283715 | J:169569
First Author: Zhou X
Year: 2011
Journal: PLoS One
Title: The mammalian class 3 PI3K (PIK3C3) is required for early embryogenesis and cell proliferation.
Volume: 6
Issue: 1
Pages: e16358
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Publication
25574476 | J:220518
First Author: Hu H
Year: 2014
Journal: Ann Clin Transl Neurol
Title: Mutations in PTRH2 cause novel infantile-onset multisystem disease with intellectual disability, microcephaly, progressive ataxia, and muscle weakness.
Volume: 1
Issue: 12
Pages: 1024-35
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Publication
21828077 | J:176679
First Author: Herzig MC
Year: 2011
Journal: Hum Mol Genet
Title: LRRK2 protein levels are determined by kinase function and are crucial for kidney and lung homeostasis in mice.
Volume: 20
Issue: 21
Pages: 4209-23
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Publication
26745759 | J:302720
First Author: Jiang ZZ
Year: 2016
Journal: Oncotarget
Title: LKB1 acts as a critical gatekeeper of ovarian primordial follicle pool.
Volume: 7
Issue: 5
Pages: 5738-53
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Publication
25271321 | J:216437
First Author: Shrestha S
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Tsc1 promotes the differentiation of memory CD8+ T cells via orchestrating the transcriptional and metabolic programs.
Volume: 111
Issue: 41
Pages: 14858-63
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Publication
18511518 | J:136406
First Author: Jiang X
Year: 2008
Journal: Am J Pathol
Title: The tuberous sclerosis complex regulates trafficking of glucose transporters and glucose uptake.
Volume: 172
Issue: 6
Pages: 1748-56
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Publication
39103523 | J:357730
First Author: Miao B
Year: 2024
Journal: Cell Res
Title: SMYD5 is a ribosomal methyltransferase that catalyzes RPL40 lysine methylation to enhance translation output and promote hepatocellular carcinoma.
Volume: 34
Issue: 9
Pages: 648-660
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Publication
30406697 | J:278480
First Author: Li Z
Year: 2019
Journal: Am J Physiol Gastrointest Liver Physiol
Title: LGR4 protects hepatocytes from injury in mouse.
Volume: 316
Issue: 1
Pages: G123-G131
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Publication
31721195 | J:303942
First Author: Mello T
Year: 2020
Journal: Int J Cancer
Title: Liver haploinsufficiency of RuvBL1 causes hepatic insulin resistance and enhances hepatocellular carcinoma progression.
Volume: 146
Issue: 12
Pages: 3410-3422
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Publication
32149416 | J:299785
First Author: Pla-Martín D
Year: 2020
Journal: EMBO J
Title: CLUH granules coordinate translation of mitochondrial proteins with mTORC1 signaling and mitophagy.
Volume: 39
Issue: 9
Pages: e102731
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Publication
22308354 | J:182628
First Author: Jaber N
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Class III PI3K Vps34 plays an essential role in autophagy and in heart and liver function.
Volume: 109
Issue: 6
Pages: 2003-8
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Publication
31174205 | J:280714
First Author: Yuskaitis CJ
Year: 2019
Journal: Hum Mol Genet
Title: Chronic mTORC1 inhibition rescues behavioral and biochemical deficits resulting from neuronal Depdc5 loss in mice.
Volume: 28
Issue: 17
Pages: 2952-2964
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Publication
19420259 | J:148479
First Author: Di Nardo A
Year: 2009
Journal: J Neurosci
Title: Tuberous sclerosis complex activity is required to control neuronal stress responses in an mTOR-dependent manner.
Volume: 29
Issue: 18
Pages: 5926-37
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Publication
21319287 | J:215873
First Author: Wu J
Year: 2012
Journal: Pediatr Blood Cancer
Title: Preclincial testing of sorafenib and RAD001 in the Nf(flox/flox) ;DhhCre mouse model of plexiform neurofibroma using magnetic resonance imaging.
Volume: 58
Issue: 2
Pages: 173-80
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15805275 | J:97360
First Author: Dasgupta B
Year: 2005
Journal: Cancer Res
Title: Proteomic analysis reveals hyperactivation of the mammalian target of rapamycin pathway in neurofibromatosis 1-associated human and mouse brain tumors.
Volume: 65
Issue: 7
Pages: 2755-60
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20124472 | J:157155
First Author: Banerjee S
Year: 2010
Journal: Cancer Res
Title: The neurofibromatosis type 1 tumor suppressor controls cell growth by regulating signal transducer and activator of transcription-3 activity in vitro and in vivo.
Volume: 70
Issue: 4
Pages: 1356-66
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Publication
31586563 | J:291064
 
First Author: Binder MS
Year: 2020
Journal: Behav Brain Res
Title: NS-Pten adult knockout mice display both quantitative and qualitative changes in urine-induced ultrasonic vocalizations.
Volume: 378
Pages: 112189
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Publication
30920436 | J:290249
First Author: Nolan SO
Year: 2019
Journal: Neuroreport
Title: Neuronal deletion of phosphatase and tensin homolog results in cerebellar motor learning dysfunction and alterations in intracellular signaling.
Volume: 30
Issue: 8
Pages: 556-561
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Publication
35626041 | J:333406
 
First Author: Kondylis V
Year: 2022
Journal: Cancers (Basel)
Title: p62 Promotes Survival and Hepatocarcinogenesis in Mice with Liver-Specific NEMO Ablation.
Volume: 14
Issue: 10
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Publication
23861892 | J:204285
First Author: Proenca CC
Year: 2013
Journal: PLoS One
Title: Atg4b-dependent autophagic flux alleviates Huntington's disease progression.
Volume: 8
Issue: 7
Pages: e68357
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Publication
33876772 | J:304843
 
First Author: Sharma V
Year: 2021
Journal: Proc Natl Acad Sci U S A
Title: 4E-BP2-dependent translation in parvalbumin neurons controls epileptic seizure threshold.
Volume: 118
Issue: 15
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Publication
35472723 | J:326592
First Author: Lee S
Year: 2022
Journal: Diabetes
Title: β-Cell Succinate Dehydrogenase Deficiency Triggers Metabolic Dysfunction and Insulinopenic Diabetes.
Volume: 71
Issue: 7
Pages: 1439-1453
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Publication
30594669 | J:291320
 
First Author: Song HL
Year: 2019
Journal: Mol Cell Neurosci
Title: Ouabain activates transcription factor EB and exerts neuroprotection in models of Alzheimer's disease.
Volume: 95
Pages: 13-24
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Publication
24534190 | J:210475
First Author: Gomez-Rodriguez J
Year: 2014
Journal: J Exp Med
Title: Itk-mediated integration of T cell receptor and cytokine signaling regulates the balance between Th17 and regulatory T cells.
Volume: 211
Issue: 3
Pages: 529-43
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Publication
29443546 | J:262191
First Author: Moriya N
Year: 2018
Journal: Am J Physiol Regul Integr Comp Physiol
Title: Akt1 deficiency diminishes skeletal muscle hypertrophy by reducing satellite cell proliferation.
Volume: 314
Issue: 5
Pages: R741-R751
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Publication
29053743 | J:245783
First Author: Vogel KR
Year: 2017
Journal: PLoS One
Title: In vitro modeling of experimental succinic semialdehyde dehydrogenase deficiency (SSADHD) using brain-derived neural stem cells.
Volume: 12
Issue: 10
Pages: e0186919
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Publication
38968109 | J:360773
First Author: Zheng W
Year: 2024
Journal: Proc Natl Acad Sci U S A
Title: TFEB safeguards trophoblast syncytialization in humans and mice.
Volume: 121
Issue: 28
Pages: e2404062121
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29472548 | J:344755
First Author: Yu Y
Year: 2018
Journal: Cell Death Dis
Title: Arginase-II activates mTORC1 through myosin-1b in vascular cell senescence and apoptosis.
Volume: 9
Issue: 3
Pages: 313
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Publication
28202907 | J:275306
 
First Author: Zhu G
Year: 2017
Journal: Sci Rep
Title: Calpain-1 deletion impairs mGluR-dependent LTD and fear memory extinction.
Volume: 7
Pages: 42788
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Publication
33839281 | J:312138
First Author: Crawford DHG
Year: 2021
Journal: Biochim Biophys Acta Mol Basis Dis
Title: Iron depletion attenuates steatosis in a mouse model of non-alcoholic fatty liver disease: Role of iron-dependent pathways.
Volume: 1867
Issue: 7
Pages: 166142
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Publication
36982451 | J:334510
 
First Author: Ramezanidoraki N
Year: 2023
Journal: Int J Mol Sci
Title: Activation of the PI3K/AKT/mTOR Pathway in Cajal-Retzius Cells Leads to Their Survival and Increases Susceptibility to Kainate-Induced Seizures.
Volume: 24
Issue: 6
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22572802 | J:241743
First Author: Kazdoba TM
Year: 2012
Journal: Dev Neurosci
Title: Development and characterization of NEX- Pten, a novel forebrain excitatory neuron-specific knockout mouse.
Volume: 34
Issue: 2-3
Pages: 198-209
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Publication
19470613 | J:149829
First Author: Ljungberg MC
Year: 2009
Journal: Dis Model Mech
Title: Rapamycin suppresses seizures and neuronal hypertrophy in a mouse model of cortical dysplasia.
Volume: 2
Issue: 7-8
Pages: 389-98
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16777079 | J:110476
First Author: Chalhoub N
Year: 2006
Journal: Brain Res
Title: S6k1 is not required for Pten-deficient neuronal hypertrophy.
Volume: 1100
Issue: 1
Pages: 32-41
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22895726 | J:187718
First Author: Weston MC
Year: 2012
Journal: J Neurosci
Title: Multiple roles for mammalian target of rapamycin signaling in both glutamatergic and GABAergic synaptic transmission.
Volume: 32
Issue: 33
Pages: 11441-52
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Publication
34440840 | J:311075
 
First Author: Biasizzo M
Year: 2021
Journal: Cells
Title: Cystatin C Deficiency Increases LPS-Induced Sepsis and NLRP3 Inflammasome Activation in Mice.
Volume: 10
Issue: 8
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Publication
29016854 | J:252236
First Author: Bartsch K
Year: 2017
Journal: Hum Mol Genet
Title: Absence of RNase H2 triggers generation of immunogenic micronuclei removed by autophagy.
Volume: 26
Issue: 20
Pages: 3960-3972
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Publication
21245374 | J:241758
First Author: Ellis JM
Year: 2011
Journal: Mol Cell Biol
Title: Mouse cardiac acyl coenzyme a synthetase 1 deficiency impairs Fatty Acid oxidation and induces cardiac hypertrophy.
Volume: 31
Issue: 6
Pages: 1252-62
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Publication
24177427 | J:207702
First Author: Riehle C
Year: 2013
Journal: J Clin Invest
Title: Insulin receptor substrate signaling suppresses neonatal autophagy in the heart.
Volume: 123
Issue: 12
Pages: 5319-33
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Publication
38722697 | J:359431
 
First Author: Waypa GB
Year: 2024
Journal: J Clin Invest
Title: Mitochondria regulate proliferation in adult cardiac myocytes.
Volume: 134
Issue: 13
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Publication
23131564 | J:191086
First Author: Walpen T
Year: 2012
Journal: Biochem Biophys Res Commun
Title: Nuclear PIM1 confers resistance to rapamycin-impaired endothelial proliferation.
Volume: 429
Issue: 1-2
Pages: 24-30
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Publication
19808022 | J:153660
First Author: Granot Z
Year: 2009
Journal: Cell Metab
Title: LKB1 regulates pancreatic beta cell size, polarity, and function.
Volume: 10
Issue: 4
Pages: 296-308
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Publication
25502776 | J:269048
 
First Author: Yuan Q
Year: 2014
Journal: Sci Rep
Title: Functional role of Calstabin2 in age-related cardiac alterations.
Volume: 4
Pages: 7425
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Publication
29228105 | J:258275
First Author: Sun X
Year: 2018
Journal: Biol Reprod
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