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Search results 3201 to 3238 out of 3238 for Psen1

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Type

Details

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Publication

20385796 | J:159279

First Author:	Coomaraswamy J
Year:	2010
Journal:	Proc Natl Acad Sci U S A
Title:	Modeling familial Danish dementia in mice supports the concept of the amyloid hypothesis of Alzheimer's disease.
Volume:	107
Issue:	17
Pages:	7969-74

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Publication

20864679 | J:166257

First Author:	Lee S
Year:	2010
Journal:	Am J Pathol
Title:	CX3CR1 deficiency alters microglial activation and reduces beta-amyloid deposition in two Alzheimer's disease mouse models.
Volume:	177
Issue:	5
Pages:	2549-62

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Publication

14637096 | J:86694

First Author:	Blanchard V
Year:	2003
Journal:	Exp Neurol
Title:	Time sequence of maturation of dystrophic neurites associated with Abeta deposits in APP/PS1 transgenic mice.
Volume:	184
Issue:	1
Pages:	247-63

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Publication

20813165 | J:169720

First Author:	Mei X
Year:	2010
Journal:	Neuroscience
Title:	Astroglial connexin immunoreactivity is specifically altered at β-amyloid plaques in β-amyloid precursor protein/presenilin1 mice.
Volume:	171
Issue:	1
Pages:	92-105

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Publication

19299585 | J:147990

First Author:	Serneels L
Year:	2009
Journal:	Science
Title:	gamma-Secretase heterogeneity in the Aph1 subunit: relevance for Alzheimer's disease.
Volume:	324
Issue:	5927
Pages:	639-42

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Publication

27723233 | J:238754

First Author:	Martin E
Year:	2017
Journal:	Aging Cell
Title:	Distinct inflammatory phenotypes of microglia and monocyte-derived macrophages in Alzheimer's disease models: effects of aging and amyloid pathology.
Volume:	16
Issue:	1
Pages:	27-38

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Publication

26468326 | J:234065

First Author:	Huang Y
Year:	2015
Journal:	Sci Transl Med
Title:	Loss of GPR3 reduces the amyloid plaque burden and improves memory in Alzheimer's disease mouse models.
Volume:	7
Issue:	309
Pages:	309ra164

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Publication

35110643 | J:324404

First Author:	McKee CA
Year:	2022
Journal:	Sci Rep
Title:	Astrocytes deficient in circadian clock gene Bmal1 show enhanced activation responses to amyloid-beta pathology without changing plaque burden.
Volume:	12
Issue:	1
Pages:	1796

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Genotype

Symbol:	Psen1/Psen1 Tg(APPSwe,tauP301L)1Lfa/Tg(APPSwe,tauP301L)1Lfa
Background:	involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Zygosity:	cx
Has Mutant Allele:	true

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Genotype

Symbol:	Psen1/Psen1 Tg(APPSwe,tauP301L)1Lfa/?
Background:	involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Zygosity:	cx
Has Mutant Allele:	true

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Genotype

Symbol:	Psen1/Psen1 Tg(APPSwe,tauP301L)1Lfa/?
Background:	B6.Cg-Psen1 Tg(APPSwe,tauP301L)1Lfa
Zygosity:	cx
Has Mutant Allele:	true

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Protein Coding Gene

MGI:1891700 | Ncstn

Type:	protein_coding_gene
Organism:	mouse, laboratory

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Publication

33508229 | J:303669

First Author:	Rustenhoven J
Year:	2021
Journal:	Cell
Title:	Functional characterization of the dural sinuses as a neuroimmune interface.
Volume:	184
Issue:	4
Pages:	1000-1016.e27

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Publication

24214350 | J:351723

First Author:	Crowe SE
Year:	2014
Journal:	J Comp Neurol
Title:	Longitudinal in vivo two-photon fluorescence imaging.
Volume:	522
Issue:	8
Pages:	1708-27

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Publication

28930663 | J:256695

First Author:	Krasemann S
Year:	2017
Journal:	Immunity
Title:	The TREM2-APOE Pathway Drives the Transcriptional Phenotype of Dysfunctional Microglia in Neurodegenerative Diseases.
Volume:	47
Issue:	3
Pages:	566-581.e9

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Publication

24307730 | J:207169

First Author:	Fisher Y
Year:	2014
Journal:	J Immunol
Title:	Th1 polarization of T cells injected into the cerebrospinal fluid induces brain immunosurveillance.
Volume:	192
Issue:	1
Pages:	92-102

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Publication

33637522 | J:327683

First Author:	Zarb Y
Year:	2021
Journal:	Sci Adv
Title:	Microglia control small vessel calcification via TREM2.
Volume:	7
Issue:	9

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Publication

16244651 | J:102879

First Author:	Jiang D
Year:	2005
Journal:	Nat Med
Title:	Regulation of lung injury and repair by Toll-like receptors and hyaluronan.
Volume:	11
Issue:	11
Pages:	1173-9

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Publication

22608241 | J:191360

First Author:	Morales-Corraliza J
Year:	2013
Journal:	Neurobiol Aging
Title:	Immunization targeting a minor plaque constituent clears β-amyloid and rescues behavioral deficits in an Alzheimer's disease mouse model.
Volume:	34
Issue:	1
Pages:	137-45

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Publication

20689579 | J:163067

First Author:	Ghosal K
Year:	2010
Journal:	PLoS One
Title:	APP intracellular domain impairs adult neurogenesis in transgenic mice by inducing neuroinflammation.
Volume:	5
Issue:	7
Pages:	e11866

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Publication

35909315 | J:334648

First Author:	Luo Q
Year:	2022
Journal:	Aging Cell
Title:	p38α-MAPK-deficient myeloid cells ameliorate symptoms and pathology of APP-transgenic Alzheimer's disease mice.
Volume:	21
Issue:	8
Pages:	e13679

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Publication

21881209 | J:178230

First Author:	Krohn M
Year:	2011
Journal:	J Clin Invest
Title:	Cerebral amyloid-β proteostasis is regulated by the membrane transport protein ABCC1 in mice.
Volume:	121
Issue:	10
Pages:	3924-31

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Publication

29382695 | J:261595

First Author:	Kress GJ
Year:	2018
Journal:	J Exp Med
Title:	Regulation of amyloid-β dynamics and pathology by the circadian clock.
Volume:	215
Issue:	4
Pages:	1059-1068

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Publication

18026102 | J:130211

First Author:	Kaeser SA
Year:	2007
Journal:	Nat Genet
Title:	Cystatin C modulates cerebral beta-amyloidosis.
Volume:	39
Issue:	12
Pages:	1437-9

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Publication

24440716 | J:208793

First Author:	Sun X
Year:	2014
Journal:	Cell Rep
Title:	miR-342-5p decreases ankyrin G levels in Alzheimer's disease transgenic mouse models.
Volume:	6
Issue:	2
Pages:	264-70

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Publication

27421117 | J:252385

First Author:	Hansen HH
Year:	2016
Journal:	PLoS One
Title:	Long-Term Treatment with Liraglutide, a Glucagon-Like Peptide-1 (GLP-1) Receptor Agonist, Has No Effect on β-Amyloid Plaque Load in Two Transgenic APP/PS1 Mouse Models of Alzheimer's Disease.
Volume:	11
Issue:	7
Pages:	e0158205

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Publication

28846081 | J:258024

First Author:	Füger P
Year:	2017
Journal:	Nat Neurosci
Title:	Microglia turnover with aging and in an Alzheimer's model via long-term in vivo single-cell imaging.
Volume:	20
Issue:	10
Pages:	1371-1376

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Genotype

Symbol:	Cx3cr1/Cx3cr1 Psen1/Psen1 Tg(APPSwe,tauP301L)1Lfa/? Tg(Thy1-YFP)HJrs/?
Background:	involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA
Zygosity:	cx
Has Mutant Allele:	true

•

Genotype

Symbol:	Cx3cr1/Cx3cr1<+> Psen1/Psen1 Tg(APPSwe,tauP301L)1Lfa/? Tg(Thy1-YFP)HJrs/?
Background:	involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA
Zygosity:	cx
Has Mutant Allele:	true

•

Protein Coding Gene

MGI:109284 | Psen2

Type:	protein_coding_gene
Organism:	mouse, laboratory

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Publication

30659012 | J:276927

First Author:	Goodwin LO
Year:	2019
Journal:	Genome Res
Title:	Large-scale discovery of mouse transgenic integration sites reveals frequent structural variation and insertional mutagenesis.
Volume:	29
Issue:	3
Pages:	494-505

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Publication

19041304 | J:174270

First Author:	Levine S
Year:	2009
Journal:	Exp Mol Pathol
Title:	Systemic pathology in aged mouse models of Down's syndrome and Alzheimer's disease.
Volume:	86
Issue:	1
Pages:	18-22

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Publication

37973869 | J:348885

First Author:	Zielinski M
Year:	2023
Journal:	Nat Neurosci
Title:	Cryo-EM of Aβ fibrils from mouse models find tg-APP(ArcSwe) fibrils resemble those found in patients with sporadic Alzheimer's disease.
Volume:	26
Issue:	12
Pages:	2073-2080

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Publication

30414727 | J:272048

First Author:	Midani-Kurçak JS
Year:	2019
Journal:	Brain Res
Title:	Effect of tau-pathology on charged multivesicular body protein 2b (CHMP2B).
Volume:	1706

Pages:	224-236

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Publication

31061494 | J:281547

First Author:	Van Hove H
Year:	2019
Journal:	Nat Neurosci
Title:	A single-cell atlas of mouse brain macrophages reveals unique transcriptional identities shaped by ontogeny and tissue environment.
Volume:	22
Issue:	6
Pages:	1021-1035

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Publication

31501572 | J:281635

First Author:	Fecher C
Year:	2019
Journal:	Nat Neurosci
Title:	Cell-type-specific profiling of brain mitochondria reveals functional and molecular diversity.
Volume:	22
Issue:	10
Pages:	1731-1742

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Publication

37749326 | J:350128

First Author:	Yin Z
Year:	2023
Journal:	Nat Immunol
Title:	APOE4 impairs the microglial response in Alzheimer's disease by inducing TGFβ-mediated checkpoints.
Volume:	24
Issue:	11
Pages:	1839-1853

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Publication

37130781 | J:335458

First Author:	Stroo E
Year:	2023
Journal:	Life Sci Alliance
Title:	Deletion of SERF2 in mice delays embryonic development and alters amyloid deposit structure in the brain.
Volume:	6
Issue:	7

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