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Search results 3201 to 3300 out of 8321 for Src

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Type Details Score
Allele
Fgr<em1(IMPC)Ccpcz> | MGI:6367971
Name: FGR proto-oncogene, Src family tyrosine kinase; endonuclease-mediated mutation 1, Institute of Molecular Genetics
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Allele
Yes1<em1(IMPC)Ccpcz> | MGI:6414517
Name: YES proto-oncogene 1, Src family tyrosine kinase; endonuclease-mediated mutation 1, Institute of Molecular Genetics
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Allele
Lyn<em1Gpt> | MGI:7301855
Name: LYN proto-oncogene, Src family tyrosine kinase; endonuclease-mediated mutation 1, GemPharmatech Co., Ltd
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
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Allele
Lyn<em2Gpt> | MGI:7301856
Name: LYN proto-oncogene, Src family tyrosine kinase; endonuclease-mediated mutation 2, GemPharmatech Co., Ltd
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Allele
Shb<em1Gpt> | MGI:7306068
Name: src homology 2 domain-containing transforming protein B; endonuclease-mediated mutation 1, GemPharmatech Co., Ltd
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Allele
Shc3<em11Gpt> | MGI:7306071
Name: src homology 2 domain-containing transforming protein C3; endonuclease-mediated mutation 11, GemPharmatech Co., Ltd
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Allele
Shc3<em1Gpt> | MGI:7306072
Name: src homology 2 domain-containing transforming protein C3; endonuclease-mediated mutation 1, GemPharmatech Co., Ltd
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
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Allele
Shd<em4Gpt> | MGI:7306076
Name: src homology 2 domain-containing transforming protein D; endonuclease-mediated mutation 4, GemPharmatech Co., Ltd
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Allele
Skap1<em10Gpt> | MGI:7306148
Name: src family associated phosphoprotein 1; endonuclease-mediated mutation 10, GemPharmatech Co., Ltd
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Allele
Skap1<em1Gpt> | MGI:7306149
Name: src family associated phosphoprotein 1; endonuclease-mediated mutation 1, GemPharmatech Co., Ltd
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
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Allele
Skap2<em1Gpt> | MGI:7306150
Name: src family associated phosphoprotein 2; endonuclease-mediated mutation 1, GemPharmatech Co., Ltd
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
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Allele
Skap2<em7Gpt> | MGI:7306151
Name: src family associated phosphoprotein 2; endonuclease-mediated mutation 7, GemPharmatech Co., Ltd
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Allele
Srcin1<em1Gpt> | MGI:7306796
Name: SRC kinase signaling inhibitor 1; endonuclease-mediated mutation 1, GemPharmatech Co., Ltd
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
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Allele
Srcin1<em6Gpt> | MGI:7306797
Name: SRC kinase signaling inhibitor 1; endonuclease-mediated mutation 6, GemPharmatech Co., Ltd
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Allele
Stac<em1Gpt> | MGI:7306875
Name: src homology three (SH3) and cysteine rich domain; endonuclease-mediated mutation 1, GemPharmatech Co., Ltd
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
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Allele
Stac<em2Gpt> | MGI:7306876
Name: src homology three (SH3) and cysteine rich domain; endonuclease-mediated mutation 2, GemPharmatech Co., Ltd
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Allele
Fgr<em1Smoc> | MGI:7289695
Name: FGR proto-oncogene, Src family tyrosine kinase; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Allele
Lyn<tm1Smoc> | MGI:7290913
Name: LYN proto-oncogene, Src family tyrosine kinase; targeted mutation 1, Shanghai Model Organisms Center
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
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Allele
Shc1<em1Smoc> | MGI:7292294
Name: src homology 2 domain-containing transforming protein C1; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
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Allele
Shc1<tm1.1Matz> | MGI:7424865
Name: src homology 2 domain-containing transforming protein C1; targeted mutation 1.1, Rachel L Matz
Allele Type: Targeted
Attribute String: Conditional ready
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Allele
Lyn<em1Fret> | MGI:7513892
Name: LYN proto-oncogene, Src family tyrosine kinase; endonuclease-mediated mutation 1, Tanya S Freedman
Allele Type: Endonuclease-mediated
Attribute String: Modified isoform(s)
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Allele
Lyn<em2Fret> | MGI:7513895
Name: LYN proto-oncogene, Src family tyrosine kinase; endonuclease-mediated mutation 2, Tanya S Freedman
Allele Type: Endonuclease-mediated
Attribute String: Modified isoform(s)
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Allele
Fgr<em1Cya> | MGI:7583799
Name: FGR proto-oncogene, Src family tyrosine kinase; endonuclease-mediated mutation 1, Cyagen Biosciences
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Allele
Fgr<em2Cya> | MGI:7583800
Name: FGR proto-oncogene, Src family tyrosine kinase; endonuclease-mediated mutation 2, Cyagen Biosciences
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
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Allele
Lyn<em2Cya> | MGI:7584898
Name: LYN proto-oncogene, Src family tyrosine kinase; endonuclease-mediated mutation 2, Cyagen Biosciences
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
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Allele
She<em2Cya> | MGI:7586495
Name: src homology 2 domain-containing transforming protein E; endonuclease-mediated mutation 2, Cyagen Biosciences
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
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Allele
Lyn<em1Smoc> | MGI:7626627
Name: LYN proto-oncogene, Src family tyrosine kinase; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Allele
Lyn<em1Cya> | MGI:7794431
Name: LYN proto-oncogene, Src family tyrosine kinase; endonuclease-mediated mutation 1, Cyagen Biosciences
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Allele
Shc1<em1Cya> | MGI:7796120
Name: src homology 2 domain-containing transforming protein C1; endonuclease-mediated mutation 1, Cyagen Biosciences
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Allele
Shc1<em2Cya> | MGI:7796121
Name: src homology 2 domain-containing transforming protein C1; endonuclease-mediated mutation 2, Cyagen Biosciences
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
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Strain
MGI:7835306 | C57BL/6JCya-Skap2<em1Cya>/Cya
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Strain
MGI:7838655 | C57BL/6JCya-Skap2<em2Cya>/Cya
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Allele
Yes1<em1Cya> | MGI:7797144
Name: YES proto-oncogene 1, Src family tyrosine kinase; endonuclease-mediated mutation 1, Cyagen Biosciences
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Allele
Yes1<em2Cya> | MGI:7797145
Name: YES proto-oncogene 1, Src family tyrosine kinase; endonuclease-mediated mutation 2, Cyagen Biosciences
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
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Genotype
Genotype
Symbol: Fgr/Fgr
Background: C3HeB/FeJ-Fgr
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Fgr/Fgr
Background: involves: C3HeB/FeJ * C57BL/6J
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Skap1/Skap1
Background: B6.129S5-Skap1
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Skap2/Skap2
Background: B6.129S5-Skap2
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Lyn/Lyn
Background: C57BL/6J-Lyn
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Lyn/Lyn
Background: C57BL/6J-Lyn
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Skap2/Skap2
Background: involves: C57BL/6J
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Lyn/Lyn
Background: C57BL/6J-Lyn
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Lyn/Lyn
Background: C57BL/6J-Lyn
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Srcin1/?
Background: Not Specified
Zygosity: ot
Has Mutant Allele: true
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Publication
30944221 | J:273825
First Author: Allen-Redpath K
Year: 2019
Journal: Proc Natl Acad Sci U S A
Title: Phospholipid membranes drive abdominal aortic aneurysm development through stimulating coagulation factor activity.
Volume: 116
Issue: 16
Pages: 8038-8047
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Publication
31594855 | J:284324
 
First Author: Ma J
Year: 2019
Journal: Sci Signal
Title: CARD9 mediates dendritic cell-induced development of Lyn deficiency-associated autoimmune and inflammatory diseases.
Volume: 12
Issue: 602
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Publication
21791602 | J:175871
First Author: Ma P
Year: 2011
Journal: Mol Cell Biol
Title: Balanced interactions between Lyn, the p85alpha regulatory subunit of class I(A) phosphatidylinositol-3-kinase, and SHIP are essential for mast cell growth and maturation.
Volume: 31
Issue: 19
Pages: 4052-62
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Protein Coding Gene
MGI:1919193 | Tom1l1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein
P98083-3
Organism: Mus musculus/domesticus
Length: 424  
Fragment?: false
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Protein
P98083-2
Organism: Mus musculus/domesticus
Length: 469  
Fragment?: false
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Publication
34877502 | J:321705
First Author: Xu Y
Year: 2021
Journal: iScience
Title: Induction of Foxp3 and activation of Tregs by HSP gp96 for treatment of autoimmune diseases.
Volume: 24
Issue: 12
Pages: 103445
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Publication
19696895 | J:162910
First Author: Shio MT
Year: 2009
Journal: PLoS Pathog
Title: Malarial hemozoin activates the NLRP3 inflammasome through Lyn and Syk kinases.
Volume: 5
Issue: 8
Pages: e1000559
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Allele
Stat3<tm1Flv> | MGI:2451328
Name: signal transducer and activator of transcription 3; targeted mutation 1, Richard A Flavell
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
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Publication
15477350 | J:93951
First Author: Zhu M
Year: 2004
Journal: J Exp Med
Title: Positive and negative regulation of FcepsilonRI-mediated signaling by the adaptor protein LAB/NTAL.
Volume: 200
Issue: 8
Pages: 991-1000
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Publication
15542585 | J:98141
First Author: Kohno M
Year: 2005
Journal: Blood
Title: Rapid and large amount of autocrine IL-3 production is responsible for mast cell survival by IgE in the absence of antigen.
Volume: 105
Issue: 5
Pages: 2059-65
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Publication
11163269 | J:66508
First Author: Sakai R
Year: 2000
Journal: Neuron
Title: The mammalian ShcB and ShcC phosphotyrosine docking proteins function in the maturation of sensory and sympathetic neurons.
Volume: 28
Issue: 3
Pages: 819-33
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Publication
16870734 | J:111058
First Author: McFarland KN
Year: 2006
Journal: J Neurosci
Title: Neural-specific inactivation of ShcA results in increased embryonic neural progenitor apoptosis and microencephaly.
Volume: 26
Issue: 30
Pages: 7885-97
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Publication
17403031 | -
First Author: Bourguignon LY
Year: 2007
Journal: J Neurochem
Title: Hyaluronan-CD44 interaction stimulates Rac1 signaling and PKN gamma kinase activation leading to cytoskeleton function and cell migration in astrocytes.
Volume: 101
Issue: 4
Pages: 1002-17
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Publication
29161354 | J:285611
First Author: Russo I
Year: 2019
Journal: Cereb Cortex
Title: p140Cap Regulates GABAergic Synaptogenesis and Development of Hippocampal Inhibitory Circuits.
Volume: 29
Issue: 1
Pages: 91-105
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Publication
22511754 | J:186204
First Author: Shao B
Year: 2012
Journal: J Biol Chem
Title: Signal-dependent slow leukocyte rolling does not require cytoskeletal anchorage of P-selectin glycoprotein ligand-1 (PSGL-1) or integrin αLβ2.
Volume: 287
Issue: 23
Pages: 19585-98
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Publication
7798194 | J:39401
First Author: Blaikie P
Year: 1994
Journal: J Biol Chem
Title: A region in Shc distinct from the SH2 domain can bind tyrosine-phosphorylated growth factor receptors.
Volume: 269
Issue: 51
Pages: 32031-4
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Publication
30271984 | J:278050
 
First Author: Shahzad K
Year: 2018
Journal: Commun Biol
Title: Activated protein C reverses epigenetically sustained p66Shc expression in plaque-associated macrophages in diabetes.
Volume: 1
Pages: 104
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Publication
8760305 | J:34966
First Author: Pelicci G
Year: 1996
Journal: Oncogene
Title: A family of Shc related proteins with conserved PTB, CH1 and SH2 regions.
Volume: 13
Issue: 3
Pages: 633-41
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Publication
23584088 | J:198517
First Author: Murphy AJ
Year: 2013
Journal: Nat Med
Title: Cholesterol efflux in megakaryocyte progenitors suppresses platelet production and thrombocytosis.
Volume: 19
Issue: 5
Pages: 586-94
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Publication
7477410 | J:29959
First Author: Barone MV
Year: 1995
Journal: Nature
Title: Myc but not Fos rescue of PDGF signalling block caused by kinase-inactive Src.
Volume: 378
Issue: 6556
Pages: 509-12
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Publication
21148430 | J:183507
First Author: Vanderlaan RD
Year: 2011
Journal: Circ Res
Title: The ShcA phosphotyrosine docking protein uses distinct mechanisms to regulate myocyte and global heart function.
Volume: 108
Issue: 2
Pages: 184-93
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Publication
20299514 | J:162825
First Author: Yago T
Year: 2010
Journal: Blood
Title: E-selectin engages PSGL-1 and CD44 through a common signaling pathway to induce integrin alphaLbeta2-mediated slow leukocyte rolling.
Volume: 116
Issue: 3
Pages: 485-94
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Publication
23015759 | J:354167
First Author: Chen YK
Year: 2012
Journal: Mol Biol Cell
Title: CTTNBP2, but not CTTNBP2NL, regulates dendritic spinogenesis and synaptic distribution of the striatin-PP2A complex.
Volume: 23
Issue: 22
Pages: 4383-92
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Publication
11433297 | -
First Author: Cavallaro U
Year: 2001
Journal: Nat Cell Biol
Title: N-CAM modulates tumour-cell adhesion to matrix by inducing FGF-receptor signalling.
Volume: 3
Issue: 7
Pages: 650-7
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Publication
10662797 | -
First Author: Gresham HD
Year: 2000
Journal: J Exp Med
Title: Negative regulation of phagocytosis in murine macrophages by the Src kinase family member, Fgr.
Volume: 191
Issue: 3
Pages: 515-28
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Publication
10022919 | -
First Author: King FJ
Year: 1999
Journal: Mol Cell Biol
Title: DEF-1, a novel Src SH3 binding protein that promotes adipogenesis in fibroblastic cell lines.
Volume: 19
Issue: 3
Pages: 2330-7
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Publication
1506682 | -
First Author: Lin J
Year: 1992
Journal: J Immunol
Title: The MB-1/B29 heterodimer couples the B cell antigen receptor to multiple src family protein tyrosine kinases.
Volume: 149
Issue: 5
Pages: 1548-55
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Publication
19265199 | -
First Author: Sun J
Year: 2009
Journal: J Biol Chem
Title: The D816V mutation of c-Kit circumvents a requirement for Src family kinases in c-Kit signal transduction.
Volume: 284
Issue: 17
Pages: 11039-47
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Publication
14691141 | -
First Author: Ling K
Year: 2003
Journal: J Cell Biol
Title: Tyrosine phosphorylation of type Igamma phosphatidylinositol phosphate kinase by Src regulates an integrin-talin switch.
Volume: 163
Issue: 6
Pages: 1339-49
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Publication
8631863 | -
First Author: Pandey A
Year: 1996
Journal: J Biol Chem
Title: Direct association between the Ret receptor tyrosine kinase and the Src homology 2-containing adapter protein Grb7.
Volume: 271
Issue: 18
Pages: 10607-10
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Publication
16380958 | -
First Author: Verbrugge A
Year: 2006
Journal: Eur J Immunol
Title: Leukocyte-associated Ig-like receptor-1 has SH2 domain-containing phosphatase-independent function and recruits C-terminal Src kinase.
Volume: 36
Issue: 1
Pages: 190-8
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Publication
15240807 | -
First Author: Hayashi T
Year: 2004
Journal: J Neurosci
Title: Tyrosine phosphorylation and regulation of the AMPA receptor by SRC family tyrosine kinases.
Volume: 24
Issue: 27
Pages: 6152-60
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Publication
11517336 | -
First Author: Grishin AV
Year: 2001
Journal: Proc Natl Acad Sci U S A
Title: Interaction between growth arrest-DNA damage protein 34 and Src kinase Lyn negatively regulates genotoxic apoptosis.
Volume: 98
Issue: 18
Pages: 10172-7
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Publication
14645715 | -
First Author: Shima T
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Transmembrane phosphoprotein Cbp senses cell adhesion signaling mediated by Src family kinase in lipid rafts.
Volume: 100
Issue: 25
Pages: 14897-902
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Publication
11884411 | -
First Author: Ikeda K
Year: 2002
Journal: J Biol Chem
Title: Discoidin domain receptor 2 interacts with Src and Shc following its activation by type I collagen.
Volume: 277
Issue: 21
Pages: 19206-12
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Publication
15494734 | -
First Author: Li W
Year: 2004
Journal: Nat Neurosci
Title: Activation of FAK and Src are receptor-proximal events required for netrin signaling.
Volume: 7
Issue: 11
Pages: 1213-21
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Publication
9177269 | -
First Author: Saouaf SJ
Year: 1997
Journal: Biochem Biophys Res Commun
Title: Palmitylation of Src family tyrosine kinases regulates functional interaction with a B cell substrate.
Volume: 234
Issue: 2
Pages: 325-9
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Publication
10449731 | -
First Author: Oda H
Year: 1999
Journal: Proc Natl Acad Sci U S A
Title: Regulation of the Src family tyrosine kinase Blk through E6AP-mediated ubiquitination.
Volume: 96
Issue: 17
Pages: 9557-62
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Publication
15254079 | -
First Author: Knöll B
Year: 2004
Journal: J Neurosci
Title: Src family kinases are involved in EphA receptor-mediated retinal axon guidance.
Volume: 24
Issue: 28
Pages: 6248-57
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Publication
11359765 | -
First Author: Malbec O
Year: 2001
Journal: J Biol Chem
Title: Src homology 2 domain-containing inositol 5-phosphatase 1 mediates cell cycle arrest by FcgammaRIIB.
Volume: 276
Issue: 32
Pages: 30381-91
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Publication
10779329 | -
First Author: Manes G
Year: 2000
Journal: Mol Cell Biol
Title: Slap negatively regulates Src mitogenic function but does not revert Src-induced cell morphology changes.
Volume: 20
Issue: 10
Pages: 3396-406
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Publication
10748127 | -
First Author: Bedford MT
Year: 2000
Journal: J Biol Chem
Title: Arginine methylation inhibits the binding of proline-rich ligands to Src homology 3, but not WW, domains.
Volume: 275
Issue: 21
Pages: 16030-6
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Publication
9891083 | -
First Author: Debnath J
Year: 1999
Journal: Mol Cell Biol
Title: rlk/TXK encodes two forms of a novel cysteine string tyrosine kinase activated by Src family kinases.
Volume: 19
Issue: 2
Pages: 1498-507
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Publication
11983165 | -
First Author: Palmer A
Year: 2002
Journal: Mol Cell
Title: EphrinB phosphorylation and reverse signaling: regulation by Src kinases and PTP-BL phosphatase.
Volume: 9
Issue: 4
Pages: 725-37
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Publication
12511554 | -
First Author: Voytyuk O
Year: 2003
Journal: J Biol Chem
Title: Src family kinases are involved in the differential signaling from two splice forms of c-Kit.
Volume: 278
Issue: 11
Pages: 9159-66
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Publication
12577064 | -
First Author: Gasman S
Year: 2003
Journal: Nat Cell Biol
Title: RhoD regulates endosome dynamics through Diaphanous-related Formin and Src tyrosine kinase.
Volume: 5
Issue: 3
Pages: 195-204
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Publication
19487280 | -
First Author: Maretzky T
Year: 2009
Journal: Cancer Res
Title: Src stimulates fibroblast growth factor receptor-2 shedding by an ADAM15 splice variant linked to breast cancer.
Volume: 69
Issue: 11
Pages: 4573-6
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Publication
21098279 | -
First Author: Aitio O
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Recognition of tandem PxxP motifs as a unique Src homology 3-binding mode triggers pathogen-driven actin assembly.
Volume: 107
Issue: 50
Pages: 21743-8
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Publication
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First Author: Moncalián G
Year: 2006
Journal: J Biol Chem
Title: Atypical polyproline recognition by the CMS N-terminal Src homology 3 domain.
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First Author: Hong E
Year: 2004
Journal: J Biol Chem
Title: Solution structure and backbone dynamics of the non-receptor protein-tyrosine kinase-6 Src homology 2 domain.
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First Author: Okkenhaug K
Year: 1998
Journal: J Biol Chem
Title: Grb2 forms an inducible protein complex with CD28 through a Src homology 3 domain-proline interaction.
Volume: 273
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First Author: Song C
Year: 2002
Journal: Am J Physiol Heart Circ Physiol
Title: Molecular conformation dictates signaling module formation: example of PKCepsilon and Src tyrosine kinase.
Volume: 282
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Title: Dynamin forms a Src kinase-sensitive complex with Cbl and regulates podosomes and osteoclast activity.
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