|  Help  |  About  |  Contact Us

Search our database by keyword

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 3301 to 3400 out of 4449 for Apc

0.025s

Categories

Hits by Pathway

Hits by Category

Hits by Strain

Type Details Score
GXD Expression  
Probe: MGI:4423063
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1757723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823173
Age: embryonic day 14.5
Image: euxassay_007719_05
Specimen Label: euxassay_007719_05
Detected: true
Specimen Num: 5
GXD Expression  
Probe: MGI:4423063
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1757723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823173
Age: embryonic day 14.5
Image: euxassay_007719_06
Specimen Label: euxassay_007719_06
Detected: true
Specimen Num: 6
GXD Expression  
Probe: MGI:4423063
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1757723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823173
Age: embryonic day 14.5
Image: euxassay_007719_07
Specimen Label: euxassay_007719_07
Detected: true
Specimen Num: 7
GXD Expression  
Probe: MGI:4423063
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1757723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823173
Age: embryonic day 14.5
Image: euxassay_007719_08
Specimen Label: euxassay_007719_08
Detected: true
Specimen Num: 8
GXD Expression  
Probe: MGI:4423063
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1757723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823173
Age: embryonic day 14.5
Image: euxassay_007719_09
Specimen Label: euxassay_007719_09
Detected: true
Specimen Num: 9
GXD Expression  
Probe: MGI:4423063
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1757723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823173
Age: embryonic day 14.5
Image: euxassay_007719_10
Specimen Label: euxassay_007719_10
Detected: true
Specimen Num: 10
GXD Expression  
Probe: MGI:4423063
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1757723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823173
Age: embryonic day 14.5
Image: euxassay_007719_11
Specimen Label: euxassay_007719_11
Detected: true
Specimen Num: 11
GXD Expression  
Probe: MGI:4423063
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1757723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823173
Age: embryonic day 14.5
Image: euxassay_007719_12
Specimen Label: euxassay_007719_12
Detected: true
Specimen Num: 12
GXD Expression  
Probe: MGI:4423063
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1757723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823173
Age: embryonic day 14.5
Image: euxassay_007719_13
Specimen Label: euxassay_007719_13
Detected: true
Specimen Num: 13
GXD Expression  
Probe: MGI:4888312
Assay Type: RNA in situ
Annotation Date: 2011-02-16
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1757723
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:4888365
Age: embryonic day 14.5
Image: Table S8
Specimen Label: Table S8
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:3042987
Assay Type: RNA in situ
Annotation Date: 2004-06-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3525628
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3043016
Age: postnatal adult
Image: 7B
Specimen Label: 7B
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:3042987
Assay Type: RNA in situ
Annotation Date: 2004-06-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1760523
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:3043000
Age: embryonic day 15.0
Image: 2C
Specimen Label: 2C
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:4423063
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1872223
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823173
Age: embryonic day 14.5
Image: euxassay_007719_01
Specimen Label: euxassay_007719_01
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:4423063
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1872223
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823173
Age: embryonic day 14.5
Image: euxassay_007719_16
Specimen Label: euxassay_007719_16
Detected: true
Specimen Num: 16
GXD Expression  
Probe: MGI:4423063
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1872223
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823173
Age: embryonic day 14.5
Image: euxassay_007719_17
Specimen Label: euxassay_007719_17
Detected: true
Specimen Num: 17
GXD Expression  
Probe: MGI:4423063
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1679823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823173
Age: embryonic day 14.5
Image: euxassay_007719_05
Specimen Label: euxassay_007719_05
Detected: true
Specimen Num: 5
GXD Expression  
Probe: MGI:3042987
Assay Type: RNA in situ
Annotation Date: 2004-06-17
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1689427
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:3043000
Age: postnatal day 2
Image: 3A
Specimen Label: 3A
Detected: true
Specimen Num: 7
GXD Expression  
Probe: MGI:3042987
Assay Type: RNA in situ
Annotation Date: 2004-06-17
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3043000
Age: postnatal day 7
Image: 3B
Specimen Label: 3B
Detected: true
Specimen Num: 8
GXD Expression  
Probe: MGI:3042987
Assay Type: RNA in situ
Annotation Date: 2004-06-17
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3043000
Age: postnatal day 10
Image: 3C
Specimen Label: 3C
Detected: true
Specimen Num: 9
GXD Expression  
Probe: MGI:3042987
Assay Type: RNA in situ
Annotation Date: 2004-06-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3043000
Age: postnatal day 12
Image: 3D
Specimen Label: 3D
Detected: true
Specimen Num: 10
GXD Expression  
Probe: MGI:3042987
Assay Type: RNA in situ
Annotation Date: 2004-06-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3043000
Age: postnatal day 16
Image: 3E
Specimen Label: 3E
Detected: true
Specimen Num: 11
GXD Expression  
Probe: MGI:3042987
Assay Type: RNA in situ
Annotation Date: 2004-06-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3043000
Age: postnatal week 10
Image: 3F
Specimen Label: 3F
Detected: true
Specimen Num: 12
GXD Expression  
Probe: MGI:4423063
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1689423
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823173
Age: embryonic day 14.5
Image: euxassay_007719_01
Specimen Label: euxassay_007719_01
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:4423063
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1689423
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823173
Age: embryonic day 14.5
Image: euxassay_007719_02
Specimen Label: euxassay_007719_02
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:4423063
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1689423
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823173
Age: embryonic day 14.5
Image: euxassay_007719_03
Specimen Label: euxassay_007719_03
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:4423063
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1689423
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823173
Age: embryonic day 14.5
Image: euxassay_007719_04
Specimen Label: euxassay_007719_04
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:4423063
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1689423
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823173
Age: embryonic day 14.5
Image: euxassay_007719_05
Specimen Label: euxassay_007719_05
Detected: true
Specimen Num: 5
GXD Expression  
Probe: MGI:4423063
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1689423
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823173
Age: embryonic day 14.5
Image: euxassay_007719_06
Specimen Label: euxassay_007719_06
Detected: true
Specimen Num: 6
GXD Expression  
Probe: MGI:4423063
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1689423
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823173
Age: embryonic day 14.5
Image: euxassay_007719_07
Specimen Label: euxassay_007719_07
Detected: true
Specimen Num: 7
GXD Expression  
Probe: MGI:4423063
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1689423
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823173
Age: embryonic day 14.5
Image: euxassay_007719_08
Specimen Label: euxassay_007719_08
Detected: true
Specimen Num: 8
GXD Expression  
Probe: MGI:4423063
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1689423
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823173
Age: embryonic day 14.5
Image: euxassay_007719_09
Specimen Label: euxassay_007719_09
Detected: true
Specimen Num: 9
GXD Expression  
Probe: MGI:4423063
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1689423
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823173
Age: embryonic day 14.5
Image: euxassay_007719_10
Specimen Label: euxassay_007719_10
Detected: true
Specimen Num: 10
GXD Expression  
Probe: MGI:4423063
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1689423
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823173
Age: embryonic day 14.5
Image: euxassay_007719_11
Specimen Label: euxassay_007719_11
Detected: true
Specimen Num: 11
GXD Expression  
Probe: MGI:4423063
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1689423
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823173
Age: embryonic day 14.5
Image: euxassay_007719_12
Specimen Label: euxassay_007719_12
Detected: true
Specimen Num: 12
GXD Expression  
Probe: MGI:4423063
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1689423
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823173
Age: embryonic day 14.5
Image: euxassay_007719_13
Specimen Label: euxassay_007719_13
Detected: true
Specimen Num: 13
GXD Expression  
Probe: MGI:4423063
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1689423
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823173
Age: embryonic day 14.5
Image: euxassay_007719_14
Specimen Label: euxassay_007719_14
Detected: true
Specimen Num: 14
GXD Expression  
Probe: MGI:4423063
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1689423
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823173
Age: embryonic day 14.5
Image: euxassay_007719_15
Specimen Label: euxassay_007719_15
Detected: true
Specimen Num: 15
GXD Expression  
Probe: MGI:4423063
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1689423
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823173
Age: embryonic day 14.5
Image: euxassay_007719_16
Specimen Label: euxassay_007719_16
Detected: true
Specimen Num: 16
GXD Expression  
Probe: MGI:4423063
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1689423
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823173
Age: embryonic day 14.5
Image: euxassay_007719_17
Specimen Label: euxassay_007719_17
Detected: true
Specimen Num: 17
GXD Expression  
Probe: MGI:4423063
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1689423
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823173
Age: embryonic day 14.5
Image: euxassay_007719_18
Specimen Label: euxassay_007719_18
Detected: true
Specimen Num: 18
GXD Expression  
Probe: MGI:4423063
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1689423
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823173
Age: embryonic day 14.5
Image: euxassay_007719_19
Specimen Label: euxassay_007719_19
Detected: true
Specimen Num: 19
GXD Expression  
Probe: MGI:4423063
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1689423
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4823173
Age: embryonic day 14.5
Image: euxassay_007719_20
Specimen Label: euxassay_007719_20
Detected: true
Specimen Num: 20
GXD Expression    
Probe: MGI:6167543
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689419
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:6189791
Age: embryonic day 11.5
Specimen Label: Table S2 - E11.5 - Apc2
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:6167543
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689421
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:6189791
Age: embryonic day 13.5
Specimen Label: Table S2 - E13.5 - Apc2
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:6167543
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689424
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:6189791
Age: embryonic day 15.5
Specimen Label: Table S2 - E15.5 - Apc2
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:6167543
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689426
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6189791
Age: embryonic day 18.5
Specimen Label: Table S2 - E18.5 - Apc2
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:6167543
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6189791
Age: postnatal day 4
Specimen Label: Table S2 - P4 - Apc2
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:6167543
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6189791
Age: postnatal day 14
Specimen Label: Table S2 - P14 - Apc2
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:6167543
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6189791
Age: postnatal day 28
Specimen Label: Table S2 - P28 - Apc2
Detected: true
Specimen Num: 7
GXD Expression  
Probe: MGI:3042987
Assay Type: RNA in situ
Annotation Date: 2004-06-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3521728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3043016
Age: postnatal adult
Image: 7E
Specimen Label: 7E
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:4423063
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:2826626
Stage: TS26
Assay Id: MGI:5540603
Age: embryonic day 17.5
Image: GUDMAP:14775
Specimen Label: GUDMAP:14775
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:4423063
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:2826628
Stage: TS28
Assay Id: MGI:5540603
Age: postnatal day 84
Image: GUDMAP:14776
Specimen Label: GUDMAP:14776
Detected: false
Specimen Num: 2
GXD Expression    
Probe: MGI:4423063
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:2772126
Stage: TS26
Assay Id: MGI:5540603
Age: embryonic day 17.5
Image: GUDMAP:14775
Specimen Label: GUDMAP:14775
Detected: false
Specimen Num: 1
GO Term
DO Term
Strain
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
Allele
Name: APC, WNT signaling pathway regulator; targeted mutation 1, Raju Kucherlapati
Allele Type: Targeted
Attribute String: Null/knockout
Allele
Name: APC, WNT signaling pathway regulator; targeted mutation 1, Makoto M Taketo
Allele Type: Targeted
Attribute String: Null/knockout
Allele  
Name: APC, WNT signaling pathway regulator; Mutation 1, Tetsuo Noda
Allele Type: Chemically induced (ENU)
DO Term
Genotype
Symbol: Sapcd2/Sapcd2<+>
Background: involves: C57BL/6NCrj * CBA/JNCrj
Zygosity: ht
Has Mutant Allele: true
Publication
First Author: Fanaee-Danesh E
Year: 2019
Journal: Biochim Biophys Acta Mol Basis Dis
Title: Astaxanthin exerts protective effects similar to bexarotene in Alzheimer's disease by modulating amyloid-beta and cholesterol homeostasis in blood-brain barrier endothelial cells.
Volume: 1865
Issue: 9
Pages: 2224-2245
Publication
First Author: Yamanaka H
Year: 2002
Journal: Brain Res Gene Expr Patterns
Title: Expression of Apc2 during mouse development.
Volume: 1
Issue: 2
Pages: 107-14
Publication
First Author: Wen Y
Year: 2004
Journal: Nat Cell Biol
Title: EB1 and APC bind to mDia to stabilize microtubules downstream of Rho and promote cell migration.
Volume: 6
Issue: 9
Pages: 820-30
Publication
First Author: Zhou Y
Year: 2003
Journal: Biochem J
Title: Differential expression, localization and activity of two alternatively spliced isoforms of human APC regulator CDH1.
Volume: 374
Issue: Pt 2
Pages: 349-58
Publication
First Author: Matsumine A
Year: 1996
Journal: Science
Title: Binding of APC to the human homolog of the Drosophila discs large tumor suppressor protein.
Volume: 272
Issue: 5264
Pages: 1020-3
Publication
First Author: Santoro IM
Year: 1997
Journal: Cancer Res
Title: Alternative splicing of the APC gene and its association with terminal differentiation.
Volume: 57
Issue: 3
Pages: 488-94
Publication
First Author: Slep KC
Year: 2005
Journal: J Cell Biol
Title: Structural determinants for EB1-mediated recruitment of APC and spectraplakins to the microtubule plus end.
Volume: 168
Issue: 4
Pages: 587-98
Publication
First Author: Kawakami K
Year: 2000
Journal: J Natl Cancer Inst
Title: Hypermethylated APC DNA in plasma and prognosis of patients with esophageal adenocarcinoma.
Volume: 92
Issue: 22
Pages: 1805-11
Publication
First Author: Day CL
Year: 2000
Journal: J Mol Biol
Title: Crystal structure of the amino-terminal coiled-coil domain of the APC tumor suppressor.
Volume: 301
Issue: 1
Pages: 147-56
Publication
First Author: Matsumoto S
Year: 2010
Journal: EMBO J
Title: Binding of APC and dishevelled mediates Wnt5a-regulated focal adhesion dynamics in migrating cells.
Volume: 29
Issue: 7
Pages: 1192-204
Allele
Name: catenin alpha 1; deletion
Allele Type: Spontaneous
Attribute String: Hypomorph
Allele
Name: APC, WNT signaling pathway regulator; targeted mutation 2, Shanghai Model Organisms Center
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
GO Term
Genotype
Symbol: Ctnnb1/Ctnnb1<+> Amer1/? Tg(Prrx1-cre)1Cjt/?
Background: involves: 129 * C57BL/6 * SJL
Zygosity: cn
Has Mutant Allele: true
Publication
First Author: Chan T
Year: 2007
Journal: FEBS Lett
Title: Ripply2 is essential for precise somite formation during mouse early development.
Volume: 581
Issue: 14
Pages: 2691-6
Allele  
Name: APC, WNT signaling pathway regulator; multiple intestinal neoplasia
Allele Type: Chemically induced (ENU)
Allele
Name: APC, WNT signaling pathway regulator; targeted mutation 1, Christine Perret
Allele Type: Targeted
Attribute String: Null/knockout
Genotype
Symbol: Apc/Apc<+>
Background: involves: 129P2/OlaHsd * C57BL/6
Zygosity: ht
Has Mutant Allele: true
Genotype
Symbol: Apc/Apc<+>
Background: involves: AKR/J * C57BL/6J
Zygosity: ht
Has Mutant Allele: true
Genotype
Symbol: Apc/Apc
Background: involves: 129S4/SvJae * C57BL/6
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Apc/Apc<+>
Background: involves: 129S2/SvPas * C57BL/6J
Zygosity: ht
Has Mutant Allele: true
Genotype
Symbol: Apc/Apc<+> Rab25/Rab25
Background: B6.Cg-Rab25 Apc
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Apc/Apc<+>
Background: involves: C57BL/6J
Zygosity: ht
Has Mutant Allele: true
Genotype
Symbol: Apc/Apc<+>
Background: either: B6JJcl.B6(D2JJcl)-Apc or (involves: C57BL/6 * C57BL/6JJcl * DBA/2JJcl)
Zygosity: ht
Has Mutant Allele: true
DO Term
Gene
Type: gene
Organism: human
Publication
First Author: Moisan A
Year: 2011
Journal: Dev Cell
Title: The WTX tumor suppressor regulates mesenchymal progenitor cell fate specification.
Volume: 20
Issue: 5
Pages: 583-596
Allele
Name: APC, WNT signaling pathway regulator; targeted mutation 1, Riccardo Fodde
Allele Type: Targeted
Attribute String: Hypomorph
Genotype
Symbol: Apc/Apc<+> Ctnna1/Ctnna1<+>
Background: involves: 129S4/SvJae * C57BL/6
Zygosity: cx
Has Mutant Allele: true
Publication
First Author: Chan CEZ
Year: 2021
Journal: PLoS One
Title: The Fc-mediated effector functions of a potent SARS-CoV-2 neutralizing antibody, SC31, isolated from an early convalescent COVID-19 patient, are essential for the optimal therapeutic efficacy of the antibody.
Volume: 16
Issue: 6
Pages: e0253487
Publication
First Author: Kumar R
Year: 2018
Journal: Nat Commun
Title: Mitochondrial uncoupling reveals a novel therapeutic opportunity for p53-defective cancers.
Volume: 9
Issue: 1
Pages: 3931
Publication
First Author: Ohta T
Year: 1999
Journal: Mol Cell
Title: ROC1, a homolog of APC11, represents a family of cullin partners with an associated ubiquitin ligase activity.
Volume: 3
Issue: 4
Pages: 535-41
Publication
First Author: Kuczera T
Year: 2011
Journal: Learn Mem
Title: The anaphase promoting complex is required for memory function in mice.
Volume: 18
Issue: 1
Pages: 49-57
Publication
First Author: Comai G
Year: 2010
Journal: Dev Dyn
Title: Expression patterns of the Wtx/Amer gene family during mouse embryonic development.
Volume: 239
Issue: 6
Pages: 1867-78
GO Term
GO Term
Publication
First Author: Tran K
Year: 2008
Journal: J Virol
Title: Accumulation of substrates of the anaphase-promoting complex (APC) during human cytomegalovirus infection is associated with the phosphorylation of Cdh1 and the dissociation and relocalization of APC subunits.
Volume: 82
Issue: 1
Pages: 529-37
HT Experiment  
Experiment Type: RNA-Seq
Study Type: Baseline
Source: ArrayExpress
Allele
Name: APC, WNT signaling pathway regulator; targeted mutation 1, Tetsuo Noda
Allele Type: Targeted
Attribute String: Conditional ready, Hypomorph