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Search results 3301 to 3400 out of 4701 for Bcl2

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Type Details Score
Publication
21622562 | J:175389
First Author: Carow B
Year: 2011
Journal: J Biol Chem
Title: Silencing suppressor of cytokine signaling-1 (SOCS1) in macrophages improves Mycobacterium tuberculosis control in an interferon-gamma (IFN-gamma)-dependent manner.
Volume: 286
Issue: 30
Pages: 26873-87
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Publication
18368052 | J:133772
First Author: Kleinman ME
Year: 2008
Journal: Nature
Title: Sequence- and target-independent angiogenesis suppression by siRNA via TLR3.
Volume: 452
Issue: 7187
Pages: 591-7
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Publication
22036947 | J:180238
First Author: Schwandt T
Year: 2012
Journal: EMBO J
Title: Expression of type I interferon by splenic macrophages suppresses adaptive immunity during sepsis.
Volume: 31
Issue: 1
Pages: 201-13
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Publication
22777843 | J:188005
First Author: Biondo C
Year: 2012
Journal: Eur J Immunol
Title: Recognition of fungal RNA by TLR7 has a nonredundant role in host defense against experimental candidiasis.
Volume: 42
Issue: 10
Pages: 2632-43
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Publication
21480215 | J:177313
First Author: Biondo C
Year: 2011
Journal: Eur J Immunol
Title: Recognition of yeast nucleic acids triggers a host-protective type I interferon response.
Volume: 41
Issue: 7
Pages: 1969-79
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Publication
21820332 | J:175845
First Author: Sharma S
Year: 2011
Journal: Immunity
Title: Innate immune recognition of an AT-rich stem-loop DNA motif in the Plasmodium falciparum genome.
Volume: 35
Issue: 2
Pages: 194-207
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Publication
23903655 | J:205017
First Author: Dorner M
Year: 2013
Journal: Nature
Title: Completion of the entire hepatitis C virus life cycle in genetically humanized mice.
Volume: 501
Issue: 7466
Pages: 237-41
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Publication
22896628 | J:189947
First Author: Weiss G
Year: 2012
Journal: J Immunol
Title: MyD88 drives the IFN-β response to Lactobacillus acidophilus in dendritic cells through a mechanism involving IRF1, IRF3, and IRF7.
Volume: 189
Issue: 6
Pages: 2860-8
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Publication
19652017 | J:152182
First Author: McWhirter SM
Year: 2009
Journal: J Exp Med
Title: A host type I interferon response is induced by cytosolic sensing of the bacterial second messenger cyclic-di-GMP.
Volume: 206
Issue: 9
Pages: 1899-911
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Publication
22474394 | J:183609
First Author: Ge J
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Preventing bacterial DNA release and absent in melanoma 2 inflammasome activation by a Legionella effector functioning in membrane trafficking.
Volume: 109
Issue: 16
Pages: 6193-8
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Publication
20975040 | J:176879
First Author: Lauterbach H
Year: 2010
Journal: J Exp Med
Title: Mouse CD8alpha+ DCs and human BDCA3+ DCs are major producers of IFN-lambda in response to poly IC.
Volume: 207
Issue: 12
Pages: 2703-17
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Publication
27001308 | J:236189
First Author: Chinnam M
Year: 2016
Journal: Mol Cell Biol
Title: Evaluating Effects of Hypomorphic Thoc1 Alleles on Embryonic Development in Rb1 Null Mice.
Volume: 36
Issue: 11
Pages: 1621-7
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Publication
26966181 | J:233705
First Author: Zhao H
Year: 2016
Journal: J Biol Chem
Title: Deletions of Retinoblastoma 1 (Rb1) and Its Repressing Target S Phase Kinase-associated protein 2 (Skp2) Are Synthetic Lethal in Mouse Embryogenesis.
Volume: 291
Issue: 19
Pages: 10201-9
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Publication
25049377 | J:212237
First Author: McComb S
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Type-I interferon signaling through ISGF3 complex is required for sustained Rip3 activation and necroptosis in macrophages.
Volume: 111
Issue: 31
Pages: E3206-13
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Publication
24637670 | J:210311
 
First Author: Takemura N
Year: 2014
Journal: Nat Commun
Title: Blockade of TLR3 protects mice from lethal radiation-induced gastrointestinal syndrome.
Volume: 5
Pages: 3492
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Publication
17893884 | J:145221
First Author: Liu G
Year: 2007
Journal: J Pathol
Title: The p53-Mdm2 network in progenitor cell expansion during mouse postnatal development.
Volume: 213
Issue: 4
Pages: 360-8
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Publication
24042114 | J:202330
First Author: Baccarella A
Year: 2013
Journal: Infect Immun
Title: Toll-like receptor 7 mediates early innate immune responses to malaria.
Volume: 81
Issue: 12
Pages: 4431-42
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Publication
18786355 | J:149874
First Author: Wetzel MK
Year: 2008
Journal: Neuron
Title: p73 regulates neurodegeneration and phospho-tau accumulation during aging and Alzheimer's disease.
Volume: 59
Issue: 5
Pages: 708-21
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Publication
24362933 | J:226672
First Author: Liehl P
Year: 2014
Journal: Nat Med
Title: Host-cell sensors for Plasmodium activate innate immunity against liver-stage infection.
Volume: 20
Issue: 1
Pages: 47-53
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Publication
19798431 | J:162908
First Author: Daffis S
Year: 2009
Journal: PLoS Pathog
Title: Induction of IFN-beta and the innate antiviral response in myeloid cells occurs through an IPS-1-dependent signal that does not require IRF-3 and IRF-7.
Volume: 5
Issue: 10
Pages: e1000607
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Publication
20107183 | J:159659
First Author: Prantner D
Year: 2010
Journal: J Immunol
Title: Stimulator of IFN gene is critical for induction of IFN-beta during Chlamydia muridarum infection.
Volume: 184
Issue: 5
Pages: 2551-60
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Publication
25694434 | J:278701
First Author: Shi X
Year: 2015
Journal: J Biol Chem
Title: The transcription factor Mesp1 interacts with cAMP-responsive element binding protein 1 (Creb1) and coactivates Ets variant 2 (Etv2) gene expression.
Volume: 290
Issue: 15
Pages: 9614-25
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Publication
23982205 | J:260330
First Author: Yang P
Year: 2013
Journal: Sci Signal
Title: Maternal hyperglycemia activates an ASK1-FoxO3a-caspase 8 pathway that leads to embryonic neural tube defects.
Volume: 6
Issue: 290
Pages: ra74
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Publication
17452523 | J:125737
First Author: Henry T
Year: 2007
Journal: J Exp Med
Title: Type I interferon signaling is required for activation of the inflammasome during Francisella infection.
Volume: 204
Issue: 5
Pages: 987-94
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Publication
31749402 | J:283328
First Author: Klimovich B
Year: 2020
Journal: Cell Cycle
Title: Inactivation of Mdm2 restores apoptosis proficiency of cooperativity mutant p53 in vivo.
Volume: 19
Issue: 1
Pages: 109-123
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Publication
20637660 | J:162548
First Author: Farlik M
Year: 2010
Journal: Immunity
Title: Nonconventional initiation complex assembly by STAT and NF-kappaB transcription factors regulates nitric oxide synthase expression.
Volume: 33
Issue: 1
Pages: 25-34
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Publication
28007900 | J:239305
First Author: Tan Q
Year: 2016
Journal: Hum Mol Genet
Title: Extensive cryptic splicing upon loss of RBM17 and TDP43 in neurodegeneration models.
Volume: 25
Issue: 23
Pages: 5083-5093
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Publication
19915568 | J:157877
First Author: Poeck H
Year: 2010
Journal: Nat Immunol
Title: Recognition of RNA virus by RIG-I results in activation of CARD9 and inflammasome signaling for interleukin 1 beta production.
Volume: 11
Issue: 1
Pages: 63-9
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Publication
21765404 | J:174513
First Author: Marichal T
Year: 2011
Journal: Nat Med
Title: DNA released from dying host cells mediates aluminum adjuvant activity.
Volume: 17
Issue: 8
Pages: 996-1002
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Publication
23422957 | J:195312
First Author: Mancino A
Year: 2013
Journal: EMBO J
Title: I kappa B kinase alpha (IKKα) activity is required for functional maturation of dendritic cells and acquired immunity to infection.
Volume: 32
Issue: 6
Pages: 816-28
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Publication
38671004 | J:347602
First Author: Shi Y
Year: 2024
Journal: Nat Commun
Title: Diphthamide deficiency promotes association of eEF2 with p53 to induce p21 expression and neural crest defects.
Volume: 15
Issue: 1
Pages: 3301
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Publication
36206490 | J:333323
First Author: Chen H
Year: 2023
Journal: Blood
Title: PRL2 phosphatase enhances oncogenic FLT3 signaling via dephosphorylation of the E3 ubiquitin ligase CBL at tyrosine 371.
Volume: 141
Issue: 3
Pages: 244-259
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Publication
27130031 | J:315123
 
First Author: Zhong J
Year: 2016
Journal: Free Radic Biol Med
Title: Superoxide dismutase 2 overexpression alleviates maternal diabetes-induced neural tube defects, restores mitochondrial function and suppresses cellular stress in diabetic embryopathy.
Volume: 96
Pages: 234-44
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Publication
22402282 | J:182585
First Author: Oh S
Year: 2012
Journal: Biochem Biophys Res Commun
Title: Histone demethylase JMJD5 is essential for embryonic development.
Volume: 420
Issue: 1
Pages: 61-5
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Publication
24013501 | J:201153
First Author: Hamard PJ
Year: 2013
Journal: Genes Dev
Title: The C terminus of p53 regulates gene expression by multiple mechanisms in a target- and tissue-specific manner in vivo.
Volume: 27
Issue: 17
Pages: 1868-85
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Publication
36856110 | J:333827
 
First Author: Huang C
Year: 2023
Journal: J Clin Invest
Title: TP63 gain-of-function mutations cause premature ovarian insufficiency by inducing oocyte apoptosis.
Volume: 133
Issue: 5
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Publication
21368833 | J:170813
First Author: Inuzuka H
Year: 2011
Journal: Nature
Title: SCF(FBW7) regulates cellular apoptosis by targeting MCL1 for ubiquitylation and destruction.
Volume: 471
Issue: 7336
Pages: 104-9
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Protein
Q9ESF4
Organism: Mus musculus/domesticus
Length: 345  
Fragment?: false
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Protein
Q8K097
Organism: Mus musculus/domesticus
Length: 317  
Fragment?: false
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Protein
Q8BJZ3
Organism: Mus musculus/domesticus
Length: 309  
Fragment?: false
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Protein
Q9DA39
Organism: Mus musculus/domesticus
Length: 238  
Fragment?: false
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Protein
Q8K191
Organism: Mus musculus/domesticus
Length: 120  
Fragment?: false
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Protein
Q3U717
Organism: Mus musculus/domesticus
Length: 309  
Fragment?: false
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Protein
A0A0G2JFN2
Organism: Mus musculus/domesticus
Length: 125  
Fragment?: true
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Protein
F7AB47
Organism: Mus musculus/domesticus
Length: 206  
Fragment?: true
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Protein
Q3TJV3
Organism: Mus musculus/domesticus
Length: 160  
Fragment?: true
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Protein
F6YG30
Organism: Mus musculus/domesticus
Length: 156  
Fragment?: true
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Protein
Q9CWB0
Organism: Mus musculus/domesticus
Length: 109  
Fragment?: false
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Protein
A0A286YDK2
Organism: Mus musculus/domesticus
Length: 198  
Fragment?: true
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Protein
Q9D561
Organism: Mus musculus/domesticus
Length: 224  
Fragment?: false
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Protein
Q3TCN7
Organism: Mus musculus/domesticus
Length: 309  
Fragment?: false
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Protein
Q570Z3
Organism: Mus musculus/domesticus
Length: 140  
Fragment?: true
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Protein
Q9D592
Organism: Mus musculus/domesticus
Length: 302  
Fragment?: false
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Publication
19704470 | -
First Author: Watanabe N
Year: 2008
Journal: Plant Signal Behav
Title: Arabidopsis Bax inhibitor-1: A rheostat for ER stress-induced programmed cell death.
Volume: 3
Issue: 8
Pages: 564-6
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Publication
19742129 | -
First Author: Watanabe N
Year: 2009
Journal: Int J Mol Sci
Title: Bax Inhibitor-1, a conserved cell death suppressor, is a key molecular switch downstream from a variety of biotic and abiotic stress signals in plants.
Volume: 10
Issue: 7
Pages: 3149-67
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Publication
24904158 | -
First Author: Chang Y
Year: 2014
Journal: Science
Title: Structural basis for a pH-sensitive calcium leak across membranes.
Volume: 344
Issue: 6188
Pages: 1131-5
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Publication
23888068 | -
First Author: Weis C
Year: 2013
Journal: J Exp Bot
Title: LIFEGUARD proteins support plant colonization by biotrophic powdery mildew fungi.
Volume: 64
Issue: 12
Pages: 3855-67
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Publication
22128171 | -
First Author: Bultynck G
Year: 2012
Journal: J Biol Chem
Title: The C terminus of Bax inhibitor-1 forms a Ca2+-permeable channel pore.
Volume: 287
Issue: 4
Pages: 2544-57
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Protein Domain
IPR006214 | Bax_inhibitor_1-related
Type: Family
Description: Bax inhibitor-1 (BI-1) []is a suppressor of apoptosis that interacts with BCL2 and BCL-X. Human Bax BI-1 is an evolutionarily conserved integral membrane protein containing multiple membrane-spanning segments localised to the ER membrane. It has 6-7 membrane-spanning domains. The C termini of the mammalian BI-1 proteins are comprised of basic amino acids resembling some nuclear targeting sequences, but otherwise the predicted proteins lack motifs that suggest this function. BI-1 also regulates cell death triggered by ER stress [, , ]. BI-1 appears to exert its effect through an interaction with calmodulin []. Crystal structure of a bacterial member reveals that these proteins mediate a calcium leak across the membrane in a pH-dependent manner. Calcium homoeostasis balances passive calcium leak with active calcium uptake. The structure exists in a pore-closed and pore-open conformation, at pHs of 8 and 6 respectively [, ].This entry represents BI-1 and related sequences, including lifeguard proteins, which resemble BI-1 and also act as apoptotic regulators [].
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Publication
22709692 | J:189078
First Author: Baba M
Year: 2012
Journal: Blood
Title: The folliculin-FNIP1 pathway deleted in human Birt-Hogg-Dubé syndrome is required for murine B-cell development.
Volume: 120
Issue: 6
Pages: 1254-61
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Publication
24415779 | J:209385
First Author: Horowitz JE
Year: 2014
Journal: J Immunol
Title: Noncore RAG1 regions promote Vβ rearrangements and αβ T cell development by overcoming inherent inefficiency of Vβ recombination signal sequences.
Volume: 192
Issue: 4
Pages: 1609-19
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Publication
10428027 | J:56509
First Author: Carmeliet P
Year: 1999
Journal: Cell
Title: Targeted deficiency or cytosolic truncation of the VE-cadherin gene in mice impairs VEGF-mediated endothelial survival and angiogenesis.
Volume: 98
Issue: 2
Pages: 147-57
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Publication
9727492 | J:49460
First Author: Li H
Year: 1998
Journal: Cell
Title: Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis.
Volume: 94
Issue: 4
Pages: 491-501
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Publication
18402774 | J:134669
First Author: Fueller J
Year: 2008
Journal: Biochem Biophys Res Commun
Title: C-RAF activation promotes BAD poly-ubiquitylation and turn-over by the proteasome.
Volume: 370
Issue: 4
Pages: 552-6
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Publication
36265442 | J:342802
First Author: Wang N
Year: 2022
Journal: Neuron
Title: Mapping brain gene coexpression in daytime transcriptomes unveils diurnal molecular networks and deciphers perturbation gene signatures.
Volume: 110
Issue: 20
Pages: 3318-3338.e9
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Publication
33959612 | J:306253
 
First Author: Flemmer RT
Year: 2021
Journal: Front Cell Dev Biol
Title: The Role of Mcl-1 in Embryonic Neural Precursor Cell Apoptosis.
Volume: 9
Pages: 659531
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Publication
25775525 | J:220677
First Author: Carrington EM
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: Prosurvival Bcl-2 family members reveal a distinct apoptotic identity between conventional and plasmacytoid dendritic cells.
Volume: 112
Issue: 13
Pages: 4044-9
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Publication
17823980 | J:125265
First Author: Peng S
Year: 2007
Journal: Eur J Immunol
Title: c-Maf interacts with c-Myb to down-regulate Bcl-2 expression and increase apoptosis in peripheral CD4 cells.
Volume: 37
Issue: 10
Pages: 2868-80
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Publication
21194678 | J:169180
First Author: Okada I
Year: 2011
Journal: Am J Hum Genet
Title: SMOC1 is essential for ocular and limb development in humans and mice.
Volume: 88
Issue: 1
Pages: 30-41
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Publication
11672537 | J:93128
First Author: Hu CJ
Year: 2001
Journal: Immunity
Title: PU.1/Spi-B regulation of c-rel is essential for mature B cell survival.
Volume: 15
Issue: 4
Pages: 545-55
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Publication
15048718 | J:88856
First Author: Kuroki A
Year: 2004
Journal: Eur J Immunol
Title: Enforced Bcl-2 expression in B lymphocytes induces rheumatoid factor and anti-DNA production, but the Yaa mutation promotes only anti-DNA production.
Volume: 34
Issue: 4
Pages: 1077-84
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Publication
14517994 | J:85918
First Author: Péquignot MO
Year: 2003
Journal: Dev Dyn
Title: Major role of BAX in apoptosis during retinal development and in establishment of a functional postnatal retina.
Volume: 228
Issue: 2
Pages: 231-8
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Publication
15256477 | J:91506
First Author: Lu YP
Year: 2004
Journal: Cancer Res
Title: Stimulatory effect of topical application of caffeine on UVB-induced apoptosis in the epidermis of p53 and Bax knockout mice.
Volume: 64
Issue: 14
Pages: 5020-7
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Publication
11298357 | J:121197
First Author: Martin LJ
Year: 2001
Journal: J Comp Neurol
Title: Injury-induced apoptosis of neurons in adult brain is mediated by p53-dependent and p53-independent pathways and requires Bax.
Volume: 433
Issue: 3
Pages: 299-311
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Publication
11212265 | J:67325
First Author: Knudson CM
Year: 2001
Journal: Cancer Res
Title: Bax accelerates tumorigenesis in p53-deficient mice.
Volume: 61
Issue: 2
Pages: 659-65
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Publication
9278319 | J:93123
First Author: O'Reilly LA
Year: 1997
Journal: J Immunol
Title: Expression of a bcl-2 transgene reduces proliferation and slows turnover of developing B lymphocytes in vivo.
Volume: 159
Issue: 5
Pages: 2301-11
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Publication
9310832 | J:93122
First Author: O'Reilly LA
Year: 1997
Journal: Int Immunol
Title: bcl-2 transgene expression promotes survival and reduces proliferation of CD3-CD4-CD8- T cell progenitors.
Volume: 9
Issue: 9
Pages: 1291-301
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Publication
34260908 | J:320567
First Author: Ortega-Molina A
Year: 2021
Journal: Cell Rep
Title: Inhibition of Rag GTPase signaling in mice suppresses B cell responses and lymphomagenesis with minimal detrimental trade-offs.
Volume: 36
Issue: 2
Pages: 109372
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Strain
MGI:5781123 | B6.Cg-Col25a1<tm1.1Tiwa> Bax<tm1Sjk>
Attribute String: targeted mutation, mutant strain, congenic
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Publication
21117150 | J:166964
First Author: Lin L
Year: 2011
Journal: Dev Dyn
Title: Sox11 regulates survival and axonal growth of embryonic sensory neurons.
Volume: 240
Issue: 1
Pages: 52-64
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Publication
15578095 | J:94431
First Author: Girgenrath M
Year: 2004
Journal: J Clin Invest
Title: Inhibition of apoptosis improves outcome in a model of congenital muscular dystrophy.
Volume: 114
Issue: 11
Pages: 1635-9
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Publication
21115610 | J:167041
First Author: Cook MS
Year: 2011
Journal: Development
Title: Regulation of male germ cell cycle arrest and differentiation by DND1 is modulated by genetic background.
Volume: 138
Issue: 1
Pages: 23-32
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Publication
17443816 | J:241692
First Author: Heitz S
Year: 2007
Journal: Dev Neurobiol
Title: BAX contributes to Doppel-induced apoptosis of prion-protein-deficient Purkinje cells.
Volume: 67
Issue: 5
Pages: 670-86
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Publication
14736860 | J:87702
First Author: Glebova NO
Year: 2004
Journal: J Neurosci
Title: Heterogeneous requirement of NGF for sympathetic target innervation in vivo.
Volume: 24
Issue: 3
Pages: 743-51
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Publication
20034568 | J:158404
First Author: Senzaki K
Year: 2010
Journal: Mol Cell Neurosci
Title: Runx3 is required for the specification of TrkC-expressing mechanoreceptive trigeminal ganglion neurons.
Volume: 43
Issue: 3
Pages: 296-307
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Publication
18385258 | J:134495
First Author: Nakamura S
Year: 2008
Journal: Development
Title: Dynamic regulation of the expression of neurotrophin receptors by Runx3.
Volume: 135
Issue: 9
Pages: 1703-11
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Publication
21967036 | J:178457
First Author: Jeong YH
Year: 2011
Journal: J Neurochem
Title: Environmental enrichment compensates for the effects of stress on disease progression in Tg2576 mice, an Alzheimer's disease model.
Volume: 119
Issue: 6
Pages: 1282-93
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Publication
26938300 | J:329127
 
First Author: Xi Y
Year: 2016
Journal: Cell Death Dis
Title: Knockout of Atg5 delays the maturation and reduces the survival of adult-generated neurons in the hippocampus.
Volume: 7
Pages: e2127
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Publication
31488565 | J:284145
 
First Author: Howard L
Year: 2019
Journal: Development
Title: CD40 forward signalling is a physiological regulator of early sensory axon growth.
Volume: 146
Issue: 18
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Publication
26224005 | J:226269
First Author: Bustamante-Marin XM
Year: 2015
Journal: Biol Reprod
Title: Left-Biased Spermatogenic Failure in 129/SvJ Dnd1Ter/+ Mice Correlates with Differences in Vascular Architecture, Oxygen Availability, and Metabolites.
Volume: 93
Issue: 3
Pages: 78
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Publication
23922915 | J:204365
First Author: Ben-Zvi A
Year: 2013
Journal: PLoS One
Title: Elimination of aberrant DRG circuitries in Sema3A mutant mice leads to extensive neuronal deficits.
Volume: 8
Issue: 7
Pages: e70085
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Publication
12019314 | J:126984
First Author: Rakowicz WP
Year: 2002
Journal: J Neurosci
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