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Search results 3301 to 3400 out of 3880 for Col2a1

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Type Details Score
DO Term
Genotype
Symbol: Tg(Col2a1*G574S)1Waho/?
Background: involves: C57BL/6 * DBA/2
Zygosity: ot
Has Mutant Allele: true
DO Term
DO Term
DO Term
DO Term
Publication
First Author: Itoh S
Year: 2013
Journal: PLoS One
Title: CCN family member 2/connective tissue growth factor (CCN2/CTGF) has anti-aging effects that protect articular cartilage from age-related degenerative changes.
Volume: 8
Issue: 8
Pages: e71156
Allele
Name: transgene insertion 1, Jacqueline Hecht
Allele Type: Transgenic
Attribute String: Inducible, Inserted expressed sequence, Transactivator
Strain
Attribute String: congenic, mutant strain, transgenic
Publication
First Author: Grant TD
Year: 2000
Journal: Dev Dyn
Title: Col2-GFP reporter marks chondrocyte lineage and chondrogenesis during mouse skeletal development.
Volume: 218
Issue: 2
Pages: 394-400
Strain
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
DO Term
DO Term
Publication
First Author: Cheah KS
Year: 1995
Journal: J Cell Biol
Title: Human COL2A1-directed SV40 T antigen expression in transgenic and chimeric mice results in abnormal skeletal development.
Volume: 128
Issue: 1-2
Pages: 223-37
Strain
Attribute String: mutant stock, transgenic
Strain
Attribute String: mutant strain, transgenic
Publication
First Author: Tang CY
Year: 2020
Journal: Biochem J
Title: Runx1 up-regulates chondrocyte to osteoblast lineage commitment and promotes bone formation by enhancing both chondrogenesis and osteogenesis.
Volume: 477
Issue: 13
Pages: 2421-2438
Publication
First Author: Deprez PM
Year: 2013
Journal: Int J Mol Sci
Title: Molecular study of a Hoxa2 gain-of-function in chondrogenesis: a model of idiopathic proportionate short stature.
Volume: 14
Issue: 10
Pages: 20386-98
Publication
First Author: Chen H
Year: 2011
Journal: Cells Tissues Organs
Title: Chondrocyte-specific regulatory activity of Runx2 is essential for survival and skeletal development.
Volume: 194
Issue: 2-4
Pages: 161-5
Publication
First Author: Deprez PM
Year: 2012
Journal: Differentiation
Title: Postnatal growth defect in mice upon persistent Hoxa2 expression in the chondrogenic cell lineage.
Volume: 83
Issue: 3
Pages: 158-67
Publication
First Author: Massip L
Year: 2007
Journal: Differentiation
Title: Expression of Hoxa2 in cells entering chondrogenesis impairs overall cartilage development.
Volume: 75
Issue: 3
Pages: 256-67
Publication
First Author: Baffi MO
Year: 2006
Journal: Dev Biol
Title: Tgfbr2 regulates the maintenance of boundaries in the axial skeleton.
Volume: 296
Issue: 2
Pages: 363-74
Allele
Name: transgene insertion 1, Erwin F Wagner
Allele Type: Transgenic
Attribute String: Reporter
Allele
Name: transgene insertion, Kathryn S E Cheah
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
Allele
Name: transgene insertion 1, Eric N Olson
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
Allele
Name: transgene insertion 2, David L Garbers
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
Allele
Name: transgene insertion 25-4, David L Garbers
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
Strain
Attribute String: transgenic, mutant strain, coisogenic
Allele
Name: transgene insertion 2, Jacqueline Hecht
Allele Type: Transgenic
Attribute String: Inducible, Inserted expressed sequence, Transactivator
Allele
Name: transgene insertion 1, Brendan Lee
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
Allele
Name: transgene insertion, Daniel H Cohn
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
Allele
Name: transgene insertion, Veronique Lefebvre
Allele Type: Transgenic
Attribute String: Reporter
Allele
Name: transgene insertion, Veronique Lefebvre
Allele Type: Transgenic
Attribute String: Reporter
Allele
Name: transgene insertion KL80.3, Kathryn S E Cheah
Allele Type: Transgenic
Attribute String: Reporter
Allele
Name: transgene insertion AA2, Kathryn S E Cheah
Allele Type: Transgenic
Attribute String: Reporter
Allele
Name: transgene insertion 05908-01-2, Takako Hattori
Allele Type: Transgenic
Attribute String: Epitope tag, Inserted expressed sequence, Reporter
Genotype
Symbol: Tg(Col2a1-rtTA,tetO-COMP)1Jath/?
Background: C57BL/6-Tg(Col2a1-rtTA,tetO-COMP)1Jath
Zygosity: ot
Has Mutant Allele: true
Genotype
Symbol: Tg(Col2a1-cre)1Bhr/Tg(Col2a1-cre)1Bhr
Background: involves: C57BL/6 * SJL
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Runx2/Runx2 Tg(Col2a1-cre)1Bhr/?
Background: involves: C57BL/6 * SJL
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Hnrnpk/Hnrnpk Tg(Col2a1-cre)1Xya/?
Background: Not Specified
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Runx2/Runx2<+> Tg(Col2a1-cre)1Bhr/?
Background: involves: C57BL/6 * SJL
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Smpd3/Smpd3 Tg(Col2a1-cre)1Bhr/?
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL
Zygosity: cn
Has Mutant Allele: true
Publication
First Author: Chokalingam K
Year: 2009
Journal: Tissue Eng Part A
Title: Three-dimensional in vitro effects of compression and time in culture on aggregate modulus and on gene expression and protein content of collagen type II in murine chondrocytes.
Volume: 15
Issue: 10
Pages: 2807-16
Publication
First Author: Nagata K
Year: 2022
Journal: Nat Commun
Title: Runx2 and Runx3 differentially regulate articular chondrocytes during surgically induced osteoarthritis development.
Volume: 13
Issue: 1
Pages: 6187
Publication  
First Author: Tsadaris SA
Year: 2024
Journal: Bone
Title: A GCaMP reporter mouse with chondrocyte specific expression of a green fluorescent calcium indicator.
Volume: 188
Pages: 117234
Publication
First Author: Han Y
Year: 2008
Journal: Mol Cell Biol
Title: L-Sox5 and Sox6 drive expression of the aggrecan gene in cartilage by securing binding of Sox9 to a far-upstream enhancer.
Volume: 28
Issue: 16
Pages: 4999-5013
Strain
Attribute String: mutant strain, congenic, targeted mutation, transgenic
Publication
First Author: Shim JH
Year: 2009
Journal: EMBO J
Title: TAK1 is an essential regulator of BMP signalling in cartilage.
Volume: 28
Issue: 14
Pages: 2028-41
Publication
First Author: Stegen S
Year: 2019
Journal: Nature
Title: HIF-1α metabolically controls collagen synthesis and modification in chondrocytes.
Volume: 565
Issue: 7740
Pages: 511-515
Publication  
First Author: Koike M
Year: 2015
Journal: Sci Rep
Title: Mechanical overloading causes mitochondrial superoxide and SOD2 imbalance in chondrocytes resulting in cartilage degeneration.
Volume: 5
Pages: 11722
Publication
First Author: Masuda I
Year: 2018
Journal: Sci Rep
Title: Apple procyanidins promote mitochondrial biogenesis and proteoglycan biosynthesis in chondrocytes.
Volume: 8
Issue: 1
Pages: 7229
Publication
First Author: Downey CM
Year: 2009
Journal: PLoS Genet
Title: Osteo-chondroprogenitor-specific deletion of the selenocysteine tRNA gene, Trsp, leads to chondronecrosis and abnormal skeletal development: a putative model for Kashin-Beck disease.
Volume: 5
Issue: 8
Pages: e1000616
Allele
Name: transgene insertion 1, Erwin F Wagner
Allele Type: Transgenic
Attribute String: Recombinase
Allele
Name: transgene insertion 3, Toshihisa Komori
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
Allele
Name: transgene insertion 1, Darwin J Prockop
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
Allele
Name: transgene insertion 1, Eero Vuorio
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
Publication  
First Author: Yan B
Year: 2016
Journal: Nat Commun
Title: mTORC1 regulates PTHrP to coordinate chondrocyte growth, proliferation and differentiation.
Volume: 7
Pages: 11151
Allele
Name: transgene insertion 1, Rene St-Arnaud
Allele Type: Transgenic
Attribute String: Recombinase
Allele
Name: transgene insertion 1, Eric N Olson
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
Publication
First Author: Zhao L
Year: 2020
Journal: Dev Biol
Title: DDB1 promotes the proliferation and hypertrophy of chondrocytes during mouse skeleton development.
Volume: 465
Issue: 2
Pages: 100-107
Allele
Name: transgene insertion 1, Eric N Olson
Allele Type: Transgenic
Attribute String: Dominant negative, Inserted expressed sequence
Strain
Attribute String: transgenic, mutant stock
Publication      
First Author: Garbers DL
Year: 2007
Journal: MGI Direct Data Submission
Title: A transgenic mouse expressing the guanylyl cyclase B1 isoform
Strain
Attribute String: mutant stock, transgenic
Strain
Attribute String: coisogenic, mutant strain, transgenic
Publication
First Author: Burger A
Year: 2020
Journal: Mol Genet Genomic Med
Title: Mutant COMP shapes growth and development of skull and facial structures in mice and humans.
Volume: 8
Issue: 7
Pages: e1251
Publication
First Author: Posey KL
Year: 2015
Journal: Hum Mol Genet
Title: Antioxidant and anti-inflammatory agents mitigate pathology in a mouse model of pseudoachondroplasia.
Volume: 24
Issue: 14
Pages: 3918-28
Strain
Attribute String: coisogenic, mutant strain, transgenic
Publication
First Author: Ruan MZ
Year: 2013
Journal: Sci Transl Med
Title: Proteoglycan 4 expression protects against the development of osteoarthritis.
Volume: 5
Issue: 176
Pages: 176ra34
Publication
First Author: Weinstein MM
Year: 2014
Journal: J Bone Miner Res
Title: Mice expressing mutant Trpv4 recapitulate the human TRPV4 disorders.
Volume: 29
Issue: 8
Pages: 1815-1822
Strain
Attribute String: mutant stock, transgenic
Genotype
Symbol: Ift88/Ift88 Tg(Col2a1-cre)1Bhr/?
Background: involves: 129P2/OlaHsd * C57BL/6 * SJL
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Tg(Col2a1-Mef2c/VP16)1Eno/?
Background: Not Specified
Zygosity: ot
Has Mutant Allele: true
Genotype
Symbol: Tg(Col2a1-Npr2*B1)2Gar/?
Background: involves: 129 * C57BL/6 * SJL
Zygosity: ot
Has Mutant Allele: true
Genotype
Symbol: Tg(Col2a1-Npr2*B2)25-4Gar/?
Background: involves: 129 * C57BL/6 * SJL
Zygosity: ot
Has Mutant Allele: true
Genotype
Symbol: n-TUtca2/n-TUtca2 Tg(Col2a1-cre)1Bhr/?
Background: B6.Cg-n-TUtca2 Tg(Col2a1-cre)1Bhr
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Tg(Col2a1-rtTA,tetO-COMP*)2Jath/?
Background: C57BL/6-Tg(Col2a1-rtTA,tetO-COMP*)2Jath
Zygosity: ot
Has Mutant Allele: true
Genotype
Symbol: Sox9/Sox9<+> Tg(Col2a1-cre)1Bhr/?
Background: involves: 129S4/SvJae * C57BL/6 * CD-1 * SJL
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Sox9/Sox9 Tg(Col2a1-cre)1Bhr/?
Background: involves: 129S4/SvJae * C57BL/6 * CD-1 * SJL
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Runx3/Runx3 Tg(Col2a1-cre)1Bhr/?
Background: involves: C57BL/6 * SJL
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Tg(Tyr,Col2a1-Trpv4*R594H)#Dhco/?
Background: involves: FVB/N
Zygosity: ot
Has Mutant Allele: true
Genotype
Symbol: Fgfr2/Fgfr2<+> Tg(Col2a1-cre)1Xya/?
Background: involves: 129S6/SvEvTac * C57BL/6J
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Xbp1/Xbp1 Tg(Col2a1-cre)1Bhr/?
Background: involves: 129S6/SvEvTac * C57BL/6 * SJL
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Smad2/Smad2 Tg(Col2a1-cre)1Bhr/?
Background: involves: 129 * C57BL/6J * CD-1 * SJL
Zygosity: cn
Has Mutant Allele: true
Publication
First Author: Saito K
Year: 2013
Journal: PLoS One
Title: Conditional inactivation of TNFα-converting enzyme in chondrocytes results in an elongated growth plate and shorter long bones.
Volume: 8
Issue: 1
Pages: e54853
Publication  
First Author: Sakagami N
Year: 2017
Journal: Orthod Craniofac Res
Title: Diverse contribution of Col2a1-expressing cells to the craniofacial skeletal cell lineages.
Volume: 20 Suppl 1
Pages: 44-49
Publication
First Author: Qi S
Year: 2022
Journal: Transgenic Res
Title: Expression of Cre recombinase in chondrocytes causes abnormal craniofacial and skeletal development.
Volume: 31
Issue: 3
Pages: 399-411
Publication
First Author: Chusho H
Year: 2001
Journal: Proc Natl Acad Sci U S A
Title: Dwarfism and early death in mice lacking C-type natriuretic peptide.
Volume: 98
Issue: 7
Pages: 4016-21
Publication
First Author: de la Croix Ndong J
Year: 2014
Journal: Nat Med
Title: Asfotase-α improves bone growth, mineralization and strength in mouse models of neurofibromatosis type-1.
Volume: 20
Issue: 8
Pages: 904-10
Publication
First Author: Ono K
Year: 2013
Journal: Hum Mol Genet
Title: The ras-GTPase activity of neurofibromin restrains ERK-dependent FGFR signaling during endochondral bone formation.
Volume: 22
Issue: 15
Pages: 3048-62
Strain
Attribute String: congenic, mutant strain, targeted mutation, transgenic
Publication  
First Author: Ding Z
Year: 2021
Journal: Bone
Title: FOXO1 expression in chondrocytes modulates cartilage production and removal in fracture healing.
Volume: 148
Pages: 115905
Publication  
First Author: Lu Y
Year: 2019
Journal: Bone
Title: Deletion of FOXO1 in chondrocytes rescues the effect of diabetes on mechanical strength in fracture healing.
Volume: 123
Pages: 159-167
Publication
First Author: Guzzo RM
Year: 2011
Journal: Int J Dev Biol
Title: Persistent expression of Twist1 in chondrocytes causes growth plate abnormalities and dwarfism in mice.
Volume: 55
Issue: 6
Pages: 641-7
Publication
First Author: Chen D
Year: 2013
Journal: J Cell Sci
Title: The transcriptional co-regulator Jab1 is crucial for chondrocyte differentiation in vivo.
Volume: 126
Issue: Pt 1
Pages: 234-43
Publication
First Author: Zhang C
Year: 2019
Journal: J Bone Miner Res
Title: Chondrocytes Promote Vascularization in Fracture Healing Through a FOXO1-Dependent Mechanism.
Volume: 34
Issue: 3
Pages: 547-556
Publication
First Author: Hosaka Y
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Notch signaling in chondrocytes modulates endochondral ossification and osteoarthritis development.
Volume: 110
Issue: 5
Pages: 1875-80
Publication
First Author: Cheng S
Year: 2016
Journal: Endocrinology
Title: Conditional Deletion of Prolyl Hydroxylase Domain-Containing Protein 2 (Phd2) Gene Reveals Its Essential Role in Chondrocyte Function and Endochondral Bone Formation.
Volume: 157
Issue: 1
Pages: 127-40
Publication
First Author: Alharbi MA
Year: 2018
Journal: Diabetes
Title: FOXO1 Deletion Reverses the Effect of Diabetic-Induced Impaired Fracture Healing.
Volume: 67
Issue: 12
Pages: 2682-2694
Publication
First Author: Lee HH
Year: 2007
Journal: PLoS One
Title: Conditional expression of Wnt4 during chondrogenesis leads to dwarfism in mice.
Volume: 2
Issue: 5
Pages: e450