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Search results 3301 to 3400 out of 4141 for Mtor

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Type Details Score
Publication
30782829 | J:274381
First Author: Hsu YT
Year: 2019
Journal: Proc Natl Acad Sci U S A
Title: Synaptic retinoic acid receptor signaling mediates mTOR-dependent metaplasticity that controls hippocampal learning.
Volume: 116
Issue: 14
Pages: 7113-7122
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22712725 | J:207658
First Author: Mebel DM
Year: 2012
Journal: Eur J Neurosci
Title: Insulin in the ventral tegmental area reduces hedonic feeding and suppresses dopamine concentration via increased reuptake.
Volume: 36
Issue: 3
Pages: 2336-46
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Publication
38386420 | J:355133
 
First Author: Hatae R
Year: 2024
Journal: JCI Insight
Title: Enhancing CAR-T cell metabolism to overcome hypoxic conditions in the brain tumor microenvironment.
Volume: 9
Issue: 7
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Publication
22993204 | J:190634
First Author: Zhao YG
Year: 2012
Journal: J Immunol
Title: Dihydroartemisinin ameliorates inflammatory disease by its reciprocal effects on Th and regulatory T cell function via modulating the mammalian target of rapamycin pathway.
Volume: 189
Issue: 9
Pages: 4417-25
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Publication
21805467 | J:179527
First Author: O'Brien TF
Year: 2011
Journal: Eur J Immunol
Title: Regulation of T-cell survival and mitochondrial homeostasis by TSC1.
Volume: 41
Issue: 11
Pages: 3361-70
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Publication
25607841 | J:217651
First Author: Zhang Y
Year: 2015
Journal: J Clin Invest
Title: GP96 is a GARP chaperone and controls regulatory T cell functions.
Volume: 125
Issue: 2
Pages: 859-69
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Publication
34467534 | J:317808
First Author: Wang X
Year: 2021
Journal: J Pathol
Title: Cardiac-specific deletion of FDPS induces cardiac remodeling and dysfunction by enhancing the activity of small GTP-binding proteins.
Volume: 255
Issue: 4
Pages: 438-450
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Publication
30031229 | J:270216
First Author: Ceylan AF
Year: 2018
Journal: Biochim Biophys Acta Mol Basis Dis
Title: Cardiomyocyte-specific knockout of endothelin receptor a attenuates obesity cardiomyopathy.
Volume: 1864
Issue: 10
Pages: 3339-3352
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Publication
30848941 | J:294073
First Author: Shi J
Year: 2019
Journal: FASEB J
Title: Disruption of both ROCK1 and ROCK2 genes in cardiomyocytes promotes autophagy and reduces cardiac fibrosis during aging.
Volume: 33
Issue: 6
Pages: 7348-7362
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Publication
25140802 | J:220999
First Author: Corrochano S
Year: 2014
Journal: PLoS One
Title: Reducing Igf-1r levels leads to paradoxical and sexually dimorphic effects in HD mice.
Volume: 9
Issue: 8
Pages: e105595
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Publication
31695068 | J:286990
First Author: Irvine EE
Year: 2019
Journal: Sci Rep
Title: Genetic deletion of S6k1 does not rescue the phenotypic deficits observed in the R6/2 mouse model of Huntington's disease.
Volume: 9
Issue: 1
Pages: 16133
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Publication
21505144 | J:182068
First Author: She P
Year: 2011
Journal: Am J Physiol Endocrinol Metab
Title: Molecular characterization of skeletal muscle atrophy in the R6/2 mouse model of Huntington's disease.
Volume: 301
Issue: 1
Pages: E49-61
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Publication
31961433 | J:286643
First Author: Gautam S
Year: 2020
Journal: Hum Mol Genet
Title: The signaling pathways implicated in impairment of hepatic autophagy in glycogen storage disease type Ia.
Volume: 29
Issue: 5
Pages: 834-844
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Publication
21341271 | J:170842
First Author: Lai C
Year: 2011
Journal: J Pathol
Title: Elevation of WNT5A expression in polyp formation in Lkb1+/- mice and Peutz-Jeghers syndrome.
Volume: 223
Issue: 5
Pages: 584-92
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Publication
18776140 | J:142419
First Author: Proulx K
Year: 2008
Journal: Diabetes
Title: Fatty acid synthase inhibitors modulate energy balance via mammalian target of rapamycin complex 1 signaling in the central nervous system.
Volume: 57
Issue: 12
Pages: 3231-8
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Publication
18614690 | J:138591
First Author: Cota D
Year: 2008
Journal: J Neurosci
Title: The role of hypothalamic mammalian target of rapamycin complex 1 signaling in diet-induced obesity.
Volume: 28
Issue: 28
Pages: 7202-8
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27294524 | J:237137
First Author: Ghosh J
Year: 2016
Journal: J Clin Invest
Title: S6K1 regulates hematopoietic stem cell self-renewal and leukemia maintenance.
Volume: 126
Issue: 7
Pages: 2621-5
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29022902 | J:273915
First Author: Kong F
Year: 2017
Journal: Cell Death Dis
Title: Differential regulation of spermatogenic process by Lkb1 isoforms in mouse testis.
Volume: 8
Issue: 10
Pages: e3121
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Publication
23451056 | J:198481
First Author: Andrade-Vieira R
Year: 2013
Journal: PLoS One
Title: Loss of LKB1 expression reduces the latency of ErbB2-mediated mammary gland tumorigenesis, promoting changes in metabolic pathways.
Volume: 8
Issue: 2
Pages: e56567
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Publication
25240456 | J:217896
 
First Author: Lai LP
Year: 2014
Journal: Bone
Title: Stk11 (Lkb1) deletion in the osteoblast lineage leads to high bone turnover, increased trabecular bone density and cortical porosity.
Volume: 69
Pages: 98-108
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Publication
19966866 | J:160400
First Author: Liang MC
Year: 2010
Journal: Oncogene
Title: TSC1 loss synergizes with KRAS activation in lung cancer development in the mouse and confers rapamycin sensitivity.
Volume: 29
Issue: 11
Pages: 1588-97
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Publication
26574479 | J:226829
First Author: Momcilovic M
Year: 2015
Journal: Cancer Res
Title: Heightening Energetic Stress Selectively Targets LKB1-Deficient Non-Small Cell Lung Cancers.
Volume: 75
Issue: 22
Pages: 4910-22
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Publication
34787081 | J:314954
   
First Author: Conde-Dusman MJ
Year: 2021
Journal: Elife
Title: Control of protein synthesis and memory by GluN3A-NMDA receptors through inhibition of GIT1/mTORC1 assembly.
Volume: 10
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23524376 | J:202417
First Author: Guo R
Year: 2013
Journal: Biochim Biophys Acta
Title: Adiponectin knockout accentuates high fat diet-induced obesity and cardiac dysfunction: role of autophagy.
Volume: 1832
Issue: 8
Pages: 1136-48
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25586965 | J:232685
First Author: Napolitano G
Year: 2015
Journal: EMBO Mol Med
Title: Impairment of chaperone-mediated autophagy leads to selective lysosomal degradation defects in the lysosomal storage disease cystinosis.
Volume: 7
Issue: 2
Pages: 158-74
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31315433 | J:327125
First Author: Zhang Q
Year: 2019
Journal: Arterioscler Thromb Vasc Biol
Title: Rheb (Ras Homolog Enriched in Brain 1) Deficiency in Mature Macrophages Prevents Atherosclerosis by Repressing Macrophage Proliferation, Inflammation, and Lipid Uptake.
Volume: 39
Issue: 9
Pages: 1787-1801
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21363918 | J:169672
First Author: Falcon BL
Year: 2011
Journal: Cancer Res
Title: Reduced VEGF production, angiogenesis, and vascular regrowth contribute to the antitumor properties of dual mTORC1/mTORC2 inhibitors.
Volume: 71
Issue: 5
Pages: 1573-83
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23563181 | J:212372
First Author: Martineau Y
Year: 2014
Journal: Oncogene
Title: Pancreatic tumours escape from translational control through 4E-BP1 loss.
Volume: 33
Issue: 11
Pages: 1367-74
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24791855 | J:217037
First Author: Weisberg E
Year: 2015
Journal: Leukemia
Title: Identification of Wee1 as a novel therapeutic target for mutant RAS-driven acute leukemia and other malignancies.
Volume: 29
Issue: 1
Pages: 27-37
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25622904 | J:244951
First Author: Tan M
Year: 2015
Journal: Neoplasia
Title: Inactivation of Sag/Rbx2/Roc2 e3 ubiquitin ligase triggers senescence and inhibits kras-induced immortalization.
Volume: 17
Issue: 1
Pages: 114-23
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21846906 | J:182171
First Author: Kim MK
Year: 2011
Journal: Am J Physiol Endocrinol Metab
Title: Promyelocytic leukemia inhibits adipogenesis, and loss of promyelocytic leukemia results in fat accumulation in mice.
Volume: 301
Issue: 6
Pages: E1130-42
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Publication
28990932 | J:252597
First Author: Johnson BG
Year: 2017
Journal: J Clin Invest
Title: Uromodulin p.Cys147Trp mutation drives kidney disease by activating ER stress and apoptosis.
Volume: 127
Issue: 11
Pages: 3954-3969
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25304685 | J:219673
First Author: Kocher BA
Year: 2015
Journal: Mol Cancer Res
Title: DAPK3 suppresses acini morphogenesis and is required for mouse development.
Volume: 13
Issue: 2
Pages: 358-67
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26485286 | J:227477
First Author: Binger KJ
Year: 2015
Journal: J Clin Invest
Title: High salt reduces the activation of IL-4- and IL-13-stimulated macrophages.
Volume: 125
Issue: 11
Pages: 4223-38
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32035093 | J:293867
First Author: Ren X
Year: 2020
Journal: J Invest Dermatol
Title: Lgr4 Deletion Delays the Hair Cycle and Inhibits the Activation of Hair Follicle Stem Cells.
Volume: 140
Issue: 9
Pages: 1706-1712.e4
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Publication
29643507 | J:261638
First Author: Liakath-Ali K
Year: 2018
Journal: Nature
Title: An evolutionarily conserved ribosome-rescue pathway maintains epidermal homeostasis.
Volume: 556
Issue: 7701
Pages: 376-380
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30760873 | J:305028
First Author: Li C
Year: 2019
Journal: Cell Death Differ
Title: mTOR-dependent upregulation of xCT blocks melanin synthesis and promotes tumorigenesis.
Volume: 26
Issue: 10
Pages: 2015-2028
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28814666 | J:283249
 
First Author: Baluk P
Year: 2017
Journal: JCI Insight
Title: Rapamycin reversal of VEGF-C-driven lymphatic anomalies in the respiratory tract.
Volume: 2
Issue: 16
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21212099 | J:169239
First Author: Malhowski AJ
Year: 2011
Journal: Hum Mol Genet
Title: Smooth muscle protein-22-mediated deletion of Tsc1 results in cardiac hypertrophy that is mTORC1-mediated and reversed by rapamycin.
Volume: 20
Issue: 7
Pages: 1290-305
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17496901 | J:121901
First Author: Hernando E
Year: 2007
Journal: Nat Med
Title: The AKT-mTOR pathway plays a critical role in the development of leiomyosarcomas.
Volume: 13
Issue: 6
Pages: 748-53
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32439824 | J:301979
First Author: Lantier L
Year: 2020
Journal: Diabetes
Title: Reciprocity Between Skeletal Muscle AMPK Deletion and Insulin Action in Diet-Induced Obese Mice.
Volume: 69
Issue: 8
Pages: 1636-1649
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24449278 | J:211212
First Author: Ou X
Year: 2014
Journal: Stem Cells
Title: SIRT1 positively regulates autophagy and mitochondria function in embryonic stem cells under oxidative stress.
Volume: 32
Issue: 5
Pages: 1183-94
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27638620 | J:237853
First Author: Kopsiaftis S
Year: 2016
Journal: Mol Cancer Res
Title: AMPKα2 Regulates Bladder Cancer Growth through SKP2-Mediated Degradation of p27.
Volume: 14
Issue: 12
Pages: 1182-1194
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34228176 | J:324585
First Author: Figueiredo M
Year: 2021
Journal: Pflugers Arch
Title: The (pro)renin receptor (ATP6ap2) facilitates receptor-mediated endocytosis and lysosomal function in the renal proximal tubule.
Volume: 473
Issue: 8
Pages: 1229-1246
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Publication
30692269 | J:272020
 
First Author: Regué L
Year: 2019
Journal: Mol Cell Biol
Title: IMP2 Increases Mouse Skeletal Muscle Mass and Voluntary Activity by Enhancing Autocrine Insulin-Like Growth Factor 2 Production and Optimizing Muscle Metabolism.
Volume: 39
Issue: 7
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Publication
37914731 | J:342411
First Author: Peng J
Year: 2023
Journal: Nat Commun
Title: Gli1 marks a sentinel muscle stem cell population for muscle regeneration.
Volume: 14
Issue: 1
Pages: 6993
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26625314 | J:309646
First Author: Zhao T
Year: 2016
Journal: Oncotarget
Title: Critical role of PPARγ in myeloid-derived suppressor cell-stimulated cancer cell proliferation and metastasis.
Volume: 7
Issue: 2
Pages: 1529-43
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22451662 | J:185445
First Author: Liu C
Year: 2012
Journal: J Biol Chem
Title: Reduction of Na/K-ATPase potentiates marinobufagenin-induced cardiac dysfunction and myocyte apoptosis.
Volume: 287
Issue: 20
Pages: 16390-8
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34101831 | J:359579
First Author: Wang L
Year: 2021
Journal: J Cell Physiol
Title: αB-crystallin/HSPB2 is critical for hyperactive mTOR-induced cardiomyopathy.
Volume: 236
Issue: 12
Pages: 8110-8121
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Publication
25643582 | J:232673
First Author: Ising C
Year: 2015
Journal: EMBO Mol Med
Title: Inhibition of insulin/IGF-1 receptor signaling protects from mitochondria-mediated kidney failure.
Volume: 7
Issue: 3
Pages: 275-87
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25581066 | J:244224
First Author: Jang SY
Year: 2015
Journal: PLoS One
Title: Autophagy is involved in the reduction of myelinating Schwann cell cytoplasm during myelin maturation of the peripheral nerve.
Volume: 10
Issue: 1
Pages: e0116624
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Publication
30696882 | J:275477
First Author: Wu Z
Year: 2019
Journal: Sci Rep
Title: Tsc1 ablation in Prx1 and Osterix lineages causes renal cystogenesis in mouse.
Volume: 9
Issue: 1
Pages: 837
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Publication
31487268 | J:284098
First Author: Katsuyama T
Year: 2019
Journal: J Clin Invest
Title: Splicing factor SRSF1 controls T cell hyperactivity and systemic autoimmunity.
Volume: 129
Issue: 12
Pages: 5411-5423
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25548102 | J:219817
First Author: Leech JD
Year: 2015
Journal: Mol Cancer Res
Title: A vascular model of Tsc1 deficiency accelerates renal tumor formation with accompanying hemangiosarcomas.
Volume: 13
Issue: 3
Pages: 548-55
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Publication
24065881 | J:312010
 
First Author: Bateup HS
Year: 2013
Journal: Front Mol Neurosci
Title: Temporal dynamics of a homeostatic pathway controlling neural network activity.
Volume: 6
Pages: 28
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21224066 | J:168083
First Author: Parker WE
Year: 2011
Journal: Am J Pathol
Title: Enhanced epidermal growth factor, hepatocyte growth factor, and vascular endothelial growth factor expression in tuberous sclerosis complex.
Volume: 178
Issue: 1
Pages: 296-305
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25658305 | J:229051
First Author: Xu Y
Year: 2015
Journal: PLoS One
Title: Ghrelin inhibits the differentiation of T helper 17 cells through mTOR/STAT3 signaling pathway.
Volume: 10
Issue: 2
Pages: e0117081
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25425965 | J:298256
First Author: Ding L
Year: 2014
Journal: Neoplasia
Title: Neurogenin 3-directed cre deletion of Tsc1 gene causes pancreatic acinar carcinoma.
Volume: 16
Issue: 11
Pages: 909-17
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Publication
24270422 | J:207832
First Author: Park Y
Year: 2013
Journal: J Clin Invest
Title: TSC1 regulates the balance between effector and regulatory T cells.
Volume: 123
Issue: 12
Pages: 5165-78
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32484794 | J:309007
 
First Author: Nechama M
Year: 2020
Journal: JCI Insight
Title: Rapamycin and dexamethasone during pregnancy prevent tuberous sclerosis complex-associated cystic kidney disease.
Volume: 5
Issue: 13
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22412198 | J:184070
First Author: Pan H
Year: 2012
Journal: J Immunol
Title: The role of tuberous sclerosis complex 1 in regulating innate immunity.
Volume: 188
Issue: 8
Pages: 3658-66
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21062901 | J:167241
First Author: Zeng LH
Year: 2011
Journal: Hum Mol Genet
Title: Tsc2 gene inactivation causes a more severe epilepsy phenotype than Tsc1 inactivation in a mouse model of tuberous sclerosis complex.
Volume: 20
Issue: 3
Pages: 445-54
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Publication
26241748 | J:228821
First Author: Huang B
Year: 2015
Journal: PLoS Genet
Title: mTORC1 Prevents Preosteoblast Differentiation through the Notch Signaling Pathway.
Volume: 11
Issue: 8
Pages: e1005426
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31353861 | J:346642
First Author: Koene LMC
Year: 2019
Journal: Ann Clin Transl Neurol
Title: Effects of antiepileptic drugs in a new TSC/mTOR-dependent epilepsy mouse model.
Volume: 6
Issue: 7
Pages: 1273-1291
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23776173 | J:205451
First Author: Pan H
Year: 2013
Journal: J Immunol
Title: Critical role of the tumor suppressor tuberous sclerosis complex 1 in dendritic cell activation of CD4 T cells by promoting MHC class II expression via IRF4 and CIITA.
Volume: 191
Issue: 2
Pages: 699-707
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25351248 | J:259054
First Author: Pryor WM
Year: 2014
Journal: Sci Signal
Title: Huntingtin promotes mTORC1 signaling in the pathogenesis of Huntington's disease.
Volume: 7
Issue: 349
Pages: ra103
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34877936 | J:336479
 
First Author: Koene LM
Year: 2021
Journal: JCI Insight
Title: Identifying the temporal electrophysiological and molecular changes that contribute to TSC-associated epileptogenesis.
Volume: 6
Issue: 23
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Publication
34135323 | J:337399
First Author: Amegandjin CA
Year: 2021
Journal: Nat Commun
Title: Sensitive period for rescuing parvalbumin interneurons connectivity and social behavior deficits caused by TSC1 loss.
Volume: 12
Issue: 1
Pages: 3653
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28637240 | J:244679
First Author: Magini A
Year: 2017
Journal: Hum Mol Genet
Title: TFEB activation restores migration ability to Tsc1-deficient adult neural stem/progenitor cells.
Volume: 26
Issue: 17
Pages: 3303-3312
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Publication
27018342 | J:286418
 
First Author: Chen LJ
Year: 2016
Journal: Peptides
Title: Angiotensin-converting enzyme 2 ameliorates renal fibrosis by blocking the activation of mTOR/ERK signaling in apolipoprotein E-deficient mice.
Volume: 79
Pages: 49-57
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Publication
16908864 | J:112917
First Author: Rossi F
Year: 2006
Journal: Proc Natl Acad Sci U S A
Title: Oncogenic Kit signaling and therapeutic intervention in a mouse model of gastrointestinal stromal tumor.
Volume: 103
Issue: 34
Pages: 12843-8
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32913260 | J:317136
First Author: Zhang ML
Year: 2020
Journal: Cell Death Dis
Title: Rac1 conditional deletion attenuates retinal ganglion cell apoptosis by accelerating autophagic flux in a mouse model of chronic ocular hypertension.
Volume: 11
Issue: 9
Pages: 734
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31593554 | J:288590
 
First Author: Matte A
Year: 2019
Journal: JCI Insight
Title: Bitopertin, a selective oral GLYT1 inhibitor, improves anemia in a mouse model of β-thalassemia.
Volume: 4
Issue: 22
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19843858 | J:153952
First Author: Qian CN
Year: 2009
Journal: Cancer Res
Title: Activation of the PI3K/AKT pathway induces urothelial carcinoma of the renal pelvis: identification in human tumors and confirmation in animal models.
Volume: 69
Issue: 21
Pages: 8256-64
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23524344 | J:198374
First Author: Rowe I
Year: 2013
Journal: Nat Med
Title: Defective glucose metabolism in polycystic kidney disease identifies a new therapeutic strategy.
Volume: 19
Issue: 4
Pages: 488-93
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30760828 | J:298004
First Author: Yheskel M
Year: 2019
Journal: Sci Rep
Title: Anti-microRNA screen uncovers miR-17 family within miR-17~92 cluster as the primary driver of kidney cyst growth.
Volume: 9
Issue: 1
Pages: 1920
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Publication
25535334 | J:224296
First Author: Wende AR
Year: 2015
Journal: Mol Cell Biol
Title: Enhanced cardiac Akt/protein kinase B signaling contributes to pathological cardiac hypertrophy in part by impairing mitochondrial function via transcriptional repression of mitochondrion-targeted nuclear genes.
Volume: 35
Issue: 5
Pages: 831-46
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Publication
31584633 | J:306742
First Author: Oka SI
Year: 2020
Journal: Cardiovasc Res
Title: Thioredoxin-1 maintains mitochondrial function via mechanistic target of rapamycin signalling in the heart.
Volume: 116
Issue: 10
Pages: 1742-1755
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Publication
26209246 | J:224834
First Author: Rimmelé P
Year: 2015
Journal: EMBO Rep
Title: Mitochondrial metabolism in hematopoietic stem cells requires functional FOXO3.
Volume: 16
Issue: 9
Pages: 1164-76
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Publication
31689244 | J:296922
First Author: Ruiz S
Year: 2020
Journal: J Clin Invest
Title: Correcting Smad1/5/8, mTOR, and VEGFR2 treats pathology in hereditary hemorrhagic telangiectasia models.
Volume: 130
Issue: 2
Pages: 942-957
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Publication
25277755 | J:218446
 
First Author: Bernard-Marissal N
Year: 2015
Journal: Neurobiol Dis
Title: Calreticulin levels determine onset of early muscle denervation by fast motoneurons of ALS model mice.
Volume: 73
Pages: 130-6
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30197586 | J:281373
 
First Author: Rodriguez L
Year: 2018
Journal: Front Mol Neurosci
Title: Human Tau Expression Does Not Induce Mouse Retina Neurodegeneration, Suggesting Differential Toxicity of Tau in Brain vs. Retinal Neurons.
Volume: 11
Pages: 293
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Publication
28119058 | J:311365
 
First Author: Klingebiel M
Year: 2017
Journal: Brain Res
Title: Analysis of ribosomal protein S6 baseline phosphorylation and effect of tau pathology in the murine brain and human hippocampus.
Volume: 1659
Pages: 121-135
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Publication
36233170 | J:330903
 
First Author: Hernandez-Lara MA
Year: 2022
Journal: Int J Mol Sci
Title: Regulation of Airway Smooth Muscle Cell Proliferation by Diacylglycerol Kinase: Relevance to Airway Remodeling in Asthma.
Volume: 23
Issue: 19
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Publication
34648564 | J:311740
First Author: Heikkinen T
Year: 2021
Journal: PLoS One
Title: Global Rhes knockout in the Q175 Huntington's disease mouse model.
Volume: 16
Issue: 10
Pages: e0258486
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