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Search results 3301 to 3383 out of 3383 for Pdx1

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Type Details Score
Publication
24280215 | J:207177
First Author: Zhou Y
Year: 2014
Journal: J Biol Chem
Title: Proteome analysis and conditional deletion of the EAAT2 glutamate transporter provide evidence against a role of EAAT2 in pancreatic insulin secretion in mice.
Volume: 289
Issue: 3
Pages: 1329-44
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33895325 | J:371460
First Author: Yang Y
Year: 2021
Journal: Mol Ther
Title: The phosphatidylserine flippase ?-subunit Tmem30a is essential for normal insulin maturation and secretion.
Volume: 29
Issue: 9
Pages: 2854-2872
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Publication
20645310 | J:164697
First Author: Vincent DF
Year: 2010
Journal: Genesis
Title: A rapid strategy to detect the recombined allele in LSL-T?RICA transgenic mice.
Volume: 48
Issue: 9
Pages: 559-62
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Publication
38733583 | J:349756
First Author: Shrestha H
Year: 2024
Journal: Cell Rep
Title: The Janus kinase 1 is critical for pancreatic cancer initiation and progression.
Volume: 43
Issue: 5
Pages: 114202
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Publication
31653840 | J:279957
First Author: Bufe B
Year: 2019
Journal: Nat Commun
Title: Bacterial MgrB peptide activates chemoreceptor Fpr3 in mouse accessory olfactory system and drives avoidance behaviour.
Volume: 10
Issue: 1
Pages: 4889
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Publication
40774250 | J:371839
First Author: Bernardo E
Year: 2025
Journal: Cell Metab
Title: HNF1A and A1CF coordinate a beta cell transcription-splicing axis that is disrupted in type 2 diabetes.
Volume: 37
Issue: 9
Pages: 1870-1889.e10
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Publication
32154941 | J:288604
First Author: Kalisz M
Year: 2020
Journal: EMBO J
Title: HNF1A recruits KDM6A to activate differentiated acinar cell programs that suppress pancreatic cancer.
Volume: 39
Issue: 9
Pages: e102808
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Publication
21362568 | J:171126
First Author: Smukler SR
Year: 2011
Journal: Cell Stem Cell
Title: The adult mouse and human pancreas contain rare multipotent stem cells that express insulin.
Volume: 8
Issue: 3
Pages: 281-93
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Publication
38908487 | J:362435
First Author: Fern?ndez ?
Year: 2024
Journal: Gastroenterology
Title: A Single-Cell Atlas of the Murine Pancreatic Ductal Tree Identifies Novel Cell Populations With Potential Implications in Pancreas Regeneration and Exocrine Pathogenesis.
Volume: 167
Issue: 5
Pages: 944-960.e15
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Publication
36919699 | J:334070
 
First Author: Chia L
Year: 2023
Journal: J Clin Invest
Title: HMGA1 induces FGF19 to drive pancreatic carcinogenesis and stroma formation.
Volume: 133
Issue: 6
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Publication
29725089 | J:349143
First Author: Crittenden MR
Year: 2018
Journal: Sci Rep
Title: Tumor cure by radiation therapy and checkpoint inhibitors depends on pre-existing immunity.
Volume: 8
Issue: 1
Pages: 7012
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Publication
35523176 | J:325642
First Author: Huang H
Year: 2022
Journal: Cancer Cell
Title: Mesothelial cell-derived antigen-presenting cancer-associated fibroblasts induce expansion of regulatory T?cells in pancreatic cancer.
Volume: 40
Issue: 6
Pages: 656-673.e7
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Publication
35122074 | J:322704
First Author: Falcomat? C
Year: 2022
Journal: Nat Cancer
Title: Selective multi-kinase inhibition sensitizes mesenchymal pancreatic cancer to immune checkpoint blockade by remodeling the tumor microenvironment.
Volume: 3
Issue: 3
Pages: 318-336
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Publication
30010625 | J:265678
First Author: Tsuda M
Year: 2018
Journal: J Clin Invest
Title: The BRG1/SOX9 axis is critical for acinar cell-derived pancreatic tumorigenesis.
Volume: 128
Issue: 8
Pages: 3475-3489
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Publication
30120146 | J:286040
 
First Author: Chen Y
Year: 2018
Journal: EMBO Mol Med
Title: Dual reporter genetic mouse models of pancreatic cancer identify an epithelial-to-mesenchymal transition-independent metastasis program.
Volume: 10
Issue: 10
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Publication
41474982 | J:385511
First Author: Kobayashi H
Year: 2026
Journal: Cancer Res
Title: Netrin-1 Promotes Pancreatic Tumorigenesis and Innervation through NEO1.
Volume: 86
Issue: 8
Pages: 1883-1901
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Publication
31439548 | J:280029
First Author: Mizutani Y
Year: 2019
Journal: Cancer Res
Title: Meflin-Positive Cancer-Associated Fibroblasts Inhibit Pancreatic Carcinogenesis.
Volume: 79
Issue: 20
Pages: 5367-5381
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Publication
26123485 | J:222392
First Author: Liu G
Year: 2015
Journal: Hum Mol Genet
Title: Selective expression of Parkinson's disease-related Leucine-rich repeat kinase 2 G2019S missense mutation in midbrain dopaminergic neurons impairs dopamine release and dopaminergic gene expression.
Volume: 24
Issue: 18
Pages: 5299-312
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Publication
31509750 | J:281075
First Author: Xue J
Year: 2019
Journal: Cell Rep
Title: CDK8 Regulates Insulin Secretion and Mediates Postnatal and Stress-Induced Expression of Neuropeptides in Pancreatic ? Cells.
Volume: 28
Issue: 11
Pages: 2892-2904.e7
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Publication
27825441 | J:237506
First Author: Houtz J
Year: 2016
Journal: Dev Cell
Title: Neurotrophin Signaling Is Required for Glucose-Induced Insulin Secretion.
Volume: 39
Issue: 3
Pages: 329-345
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Publication
34385258 | J:321932
First Author: Rovira M
Year: 2021
Journal: Genes Dev
Title: REST is a major negative regulator of endocrine differentiation during pancreas organogenesis.
Volume: 35
Issue: 17-18
Pages: 1229-1242
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31548432 | J:280398
First Author: Mameishvili E
Year: 2019
Journal: Proc Natl Acad Sci U S A
Title: Aldh1b1 expression defines progenitor cells in the adult pancreas and is required for Kras-induced pancreatic cancer.
Volume: 116
Issue: 41
Pages: 20679-20688
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Publication
37171959 | J:337581
First Author: Lacombe J
Year: 2023
Journal: Cell Rep
Title: Vitamin K-dependent carboxylation regulates Ca(2+) flux and adaptation to metabolic stress in ? cells.
Volume: 42
Issue: 5
Pages: 112500
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Publication
36309517 | J:359393
First Author: Dickerson MT
Year: 2022
Journal: Nat Commun
Title: G(i/o) protein-coupled receptor inhibition of beta-cell electrical excitability and insulin secretion depends on Na(+)/K(+) ATPase activation.
Volume: 13
Issue: 1
Pages: 6461
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Publication
32359405 | J:370196
First Author: Hu R
Year: 2020
Journal: Dev Cell
Title: Myt Transcription Factors Prevent Stress-Response Gene Overactivation to Enable Postnatal Pancreatic ? Cell Proliferation, Function, and Survival.
Volume: 53
Issue: 4
Pages: 390-405.e10
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Publication
32304665 | J:290208
First Author: Chung KM
Year: 2020
Journal: Cell
Title: Endocrine-Exocrine Signaling Drives Obesity-Associated Pancreatic Ductal Adenocarcinoma.
Volume: 181
Issue: 4
Pages: 832-847.e18
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Publication
41581147 | J:379667
First Author: Lan L
Year: 2026
Journal: Cell Rep
Title: A Jagged1-regulated hybrid-EMT state identifies pancreatic cancer stem cells.
Volume: 45
Issue: 2
Pages: 116909
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Publication
37345534 | J:338197
First Author: Nakamura T
Year: 2023
Journal: J Pathol
Title: ELF3 suppresses gallbladder cancer development through downregulation of the EREG/EGFR/mTOR complex 1 signalling pathway.
Volume: 261
Issue: 1
Pages: 28-42
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Publication
27292635 | J:238302
First Author: Byrne KT
Year: 2016
Journal: Cell Rep
Title: CD40 Stimulation Obviates Innate Sensors and Drives T Cell Immunity in Cancer.
Volume: 15
Issue: 12
Pages: 2719-32
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Publication
30926808 | J:273330
First Author: Barilla RM
Year: 2019
Journal: Nat Commun
Title: Specialized dendritic cells induce tumor-promoting IL-10(+)IL-17(+) FoxP3(neg) regulatory CD4(+) T cells in pancreatic carcinoma.
Volume: 10
Issue: 1
Pages: 1424
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Publication
36351408 | J:331107
First Author: Ramakrishnan G
Year: 2022
Journal: Cell Rep
Title: NF1 loss of function as an alternative initiating event in pancreatic ductal adenocarcinoma.
Volume: 41
Issue: 6
Pages: 111623
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Publication
27585860 | J:241899
 
First Author: Muzumdar MD
Year: 2016
Journal: Nat Commun
Title: Clonal dynamics following p53 loss of heterozygosity in Kras-driven cancers.
Volume: 7
Pages: 12685
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Publication
26261055 | J:236511
 
First Author: Yu R
Year: 2016
Journal: Mol Cell Endocrinol
Title: Animal models of spontaneous pancreatic neuroendocrine tumors.
Volume: 421
Pages: 60-7
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Publication
22034435 | J:177853
First Author: Shakya R
Year: 2011
Journal: Science
Title: BRCA1 tumor suppression depends on BRCT phosphoprotein binding, but not its E3 ligase activity.
Volume: 334
Issue: 6055
Pages: 525-8
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Publication
27215660 | J:236047
First Author: Gruber R
Year: 2016
Journal: Gastroenterology
Title: YAP1 and TAZ Control Pancreatic Cancer Initiation in Mice by Direct Up-regulation of JAK-STAT3 Signaling.
Volume: 151
Issue: 3
Pages: 526-39
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Publication
20018721 | J:156461
First Author: Morton JP
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Mutant p53 drives metastasis and overcomes growth arrest/senescence in pancreatic cancer.
Volume: 107
Issue: 1
Pages: 246-51
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Publication
28249168 | J:256196
First Author: Rajbhandari N
Year: 2017
Journal: Cell Rep
Title: Autocrine IGF1 Signaling Mediates Pancreatic Tumor Cell Dormancy in the Absence of Oncogenic Drivers.
Volume: 18
Issue: 9
Pages: 2243-2255
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Publication
33626352 | J:304305
First Author: Tomita H
Year: 2021
Journal: Cell Rep
Title: Inhibition of FGF10-ERK signal activation suppresses intraductal papillary neoplasm of the bile duct and its associated carcinomas.
Volume: 34
Issue: 8
Pages: 108772
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Publication
33990661 | J:314449
First Author: Shrivastava V
Year: 2021
Journal: Sci Rep
Title: Beta cell adaptation to pregnancy requires prolactin action on both beta and non-beta cells.
Volume: 11
Issue: 1
Pages: 10372
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Publication
40993391 | J:378221
First Author: Li H
Year: 2025
Journal: Nature
Title: SPP1 is required for maintaining mesenchymal cell fate in pancreatic cancer.
Volume: 648
Issue: 8092
Pages: 203-209
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Publication
28178232 | J:243963
First Author: Genovese G
Year: 2017
Journal: Nature
Title: Synthetic vulnerabilities of mesenchymal subpopulations in pancreatic cancer.
Volume: 542
Issue: 7641
Pages: 362-366
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Publication
28325479 | J:251956
First Author: Chambers AP
Year: 2017
Journal: Cell Metab
Title: The Role of Pancreatic Preproglucagon in Glucose Homeostasis in Mice.
Volume: 25
Issue: 4
Pages: 927-934.e3
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Publication
28053125 | J:240920
First Author: Cain-Hom C
Year: 2017
Journal: Nucleic Acids Res
Title: Efficient mapping of transgene integration sites and local structural changes in Cre transgenic mice using targeted locus amplification.
Volume: 45
Issue: 8
Pages: e62
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Publication
31451639 | J:279325
First Author: Chang H
Year: 2019
Journal: Proc Natl Acad Sci U S A
Title: Efficient genome-wide first-generation phenotypic screening system in mice using the piggyBac transposon.
Volume: 116
Issue: 37
Pages: 18507-18516
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Publication
31937792 | J:292860
First Author: Sakamoto K
Year: 2020
Journal: Sci Rep
Title: Efficient tissue-type specific expression of target genes in a tetracycline-controlled manner from the ubiquitously active Eef1a1 locus.
Volume: 10
Issue: 1
Pages: 207
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Publication
20824628 | J:166612
First Author: Song J
Year: 2010
Journal: Genesis
Title: Brain expression of Cre recombinase driven by pancreas-specific promoters.
Volume: 48
Issue: 11
Pages: 628-34
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Publication
29223399 | J:268568
First Author: Kim H
Year: 2018
Journal: Biochem Biophys Res Commun
Title: Ectopic serotonin production in ?-cell specific transgenic mice.
Volume: 495
Issue: 2
Pages: 1986-1991
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Publication
25485836 | J:220259
First Author: Rad R
Year: 2015
Journal: Nat Genet
Title: A conditional piggyBac transposition system for genetic screening in mice identifies oncogenic networks in pancreatic cancer.
Volume: 47
Issue: 1
Pages: 47-56
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Publication
26592448 | J:228015
First Author: Diersch S
Year: 2016
Journal: Oncogene
Title: Kras(G12D) induces EGFR-MYC cross signaling in murine primary pancreatic ductal epithelial cells.
Volume: 35
Issue: 29
Pages: 3880-6
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Publication
26119937 | J:234215
First Author: Hessmann E
Year: 2016
Journal: Oncogene
Title: MYC in pancreatic cancer: novel mechanistic insights and their translation into therapeutic strategies.
Volume: 35
Issue: 13
Pages: 1609-18
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Publication
33741967 | J:303829
First Author: Alicea-Torres K
Year: 2021
Journal: Nat Commun
Title: Immune suppressive activity of myeloid-derived suppressor cells in cancer requires inactivation of the type I interferon pathway.
Volume: 12
Issue: 1
Pages: 1717
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Publication
38924548 | J:350485
First Author: Brunet M
Year: 2024
Journal: J Pathol
Title: The E3 ubiquitin ligase TRIP12 is required for pancreatic acinar cell plasticity and pancreatic carcinogenesis.
Volume: 263
Issue: 4-5
Pages: 466-481
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Publication
40816286 | J:372386
First Author: Salom? Coll C
Year: 2025
Journal: Dev Cell
Title: ER-phagy and proteostasis defects prime pancreatic epithelial state changes in KRAS-mediated oncogenesis.
Volume: 60
Issue: 24
Pages: 3403-3420.e13
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Publication
29384525 | J:267927
First Author: Hassan Z
Year: 2018
Journal: Br J Cancer
Title: MTOR inhibitor-based combination therapies for pancreatic cancer.
Volume: 118
Issue: 3
Pages: 366-377
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Publication
27721407 | J:241090
First Author: Stojanovic N
Year: 2017
Journal: Oncogene
Title: HDAC1 and HDAC2 integrate the expression of p53 mutants in pancreatic cancer.
Volume: 36
Issue: 13
Pages: 1804-1815
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Publication
33810510 | J:307755
 
First Author: Poelaert BJ
Year: 2021
Journal: Cancers (Basel)
Title: Amyloid Precursor-like Protein 2 Expression Increases during Pancreatic Cancer Development and Shortens the Survival of a Spontaneous Mouse Model of Pancreatic Cancer.
Volume: 13
Issue: 7
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Publication
39072369 | J:366255
   
First Author: van der Heijden ME
Year: 2024
Journal: Elife
Title: Cerebellar nuclei cells produce distinct pathogenic spike signatures in mouse models of ataxia, dystonia, and tremor.
Volume: 12
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Publication
41906117 | J:386526
 
First Author: Umapathysivam MM
Year: 2026
Journal: Genome Med
Title: Type 2 diabetes risk alleles in peptidyl-glycine alpha-amidating monooxygenase influence GLP-1 levels and response to GLP-1 receptor agonists.
Volume: 18
Issue: 1
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Publication
31844668 | J:292306
First Author: Francis R
Year: 2019
Journal: Sci Adv
Title: Gastrointestinal transcription factors drive lineage-specific developmental programs in organ specification and cancer.
Volume: 5
Issue: 12
Pages: eaax8898
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Publication
32241947 | J:286610
First Author: Badgley MA
Year: 2020
Journal: Science
Title: Cysteine depletion induces pancreatic tumor ferroptosis in mice.
Volume: 368
Issue: 6486
Pages: 85-89
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Publication
34314386 | J:348886
 
First Author: Wan J
Year: 2021
Journal: JCI Insight
Title: Pancreas-specific CHRM3 activation causes pancreatitis in mice.
Volume: 6
Issue: 17
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Publication
32355214 | J:297756
First Author: Zebertavage LK
Year: 2020
Journal: Sci Rep
Title: Transcriptional Upregulation of NLRC5 by Radiation Drives STING- and Interferon-Independent MHC-I Expression on Cancer Cells and T Cell Cytotoxicity.
Volume: 10
Issue: 1
Pages: 7376
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Publication
33667385 | J:303521
First Author: Chen Y
Year: 2021
Journal: Cancer Cell
Title: Type I collagen deletion in ?SMA(+) myofibroblasts augments immune suppression and accelerates progression of pancreatic cancer.
Volume: 39
Issue: 4
Pages: 548-565.e6
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
37541213 | J:338908
First Author: Jiang Z
Year: 2023
Journal: Cell Stem Cell
Title: Tff2 defines transit-amplifying pancreatic acinar progenitors that lack regenerative potential and are protective against Kras-driven carcinogenesis.
Volume: 30
Issue: 8
Pages: 1091-1109.e7
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Publication
29920276 | J:263869
First Author: Parajuli P
Year: 2018
Journal: Dev Cell
Title: Twist1 Activation in Muscle Progenitor Cells Causes Muscle Loss Akin to Cancer Cachexia.
Volume: 45
Issue: 6
Pages: 712-725.e6
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Publication
37072485 | J:335080
First Author: Medler TR
Year: 2023
Journal: Sci Rep
Title: Tumor resident memory CD8 T cells and concomitant tumor immunity develop independently of CD4 help.
Volume: 13
Issue: 1
Pages: 6277
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Publication
25326799 | J:218155
First Author: Sch?nhuber N
Year: 2014
Journal: Nat Med
Title: A next-generation dual-recombinase system for time- and host-specific targeting of pancreatic cancer.
Volume: 20
Issue: 11
Pages: 1340-1347
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Publication
31239386 | J:282549
First Author: Mastio J
Year: 2019
Journal: J Exp Med
Title: Identification of monocyte-like precursors of granulocytes in cancer as a mechanism for accumulation of PMN-MDSCs.
Volume: 216
Issue: 9
Pages: 2150-2169
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Publication
31685994 | J:280854
First Author: Wang VM
Year: 2019
Journal: Nat Cell Biol
Title: CD9 identifies pancreatic cancer stem cells and modulates glutamine metabolism to fuel tumour growth.
Volume: 21
Issue: 11
Pages: 1425-1435
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Publication
41760660 | J:382990
 
First Author: Garcia CC
Year: 2026
Journal: Nat Commun
Title: Beta cell-derived cholecystokinin drives obesity-associated pancreatic adenocarcinoma development.
Volume: 17
Issue: 1
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Publication
30700911 | J:270381
First Author: Messal HA
Year: 2019
Journal: Nature
Title: Tissue curvature and apicobasal mechanical tension imbalance instruct cancer morphogenesis.
Volume: 566
Issue: 7742
Pages: 126-130
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Publication
36175792 | J:333728
First Author: Rahrmann EP
Year: 2022
Journal: Nat Genet
Title: The NALCN channel regulates metastasis and nonmalignant cell dissemination.
Volume: 54
Issue: 12
Pages: 1827-1838
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Publication
28813661 | J:260582
First Author: Zhu Y
Year: 2017
Journal: Immunity
Title: Tissue-Resident Macrophages in Pancreatic Ductal Adenocarcinoma Originate from Embryonic Hematopoiesis and Promote Tumor Progression.
Volume: 47
Issue: 2
Pages: 323-338.e6
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Publication
40044861 | J:365589
First Author: Perelli L
Year: 2025
Journal: Nature
Title: Evolutionary fingerprints of epithelial-to-mesenchymal transition.
Volume: 640
Issue: 8060
Pages: 1083-1092
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Publication
27297878 | J:236027
 
First Author: Khoriaty R
Year: 2016
Journal: Sci Rep
Title: Pancreatic SEC23B deficiency is sufficient to explain the perinatal lethality of germline SEC23B deficiency in mice.
Volume: 6
Pages: 27802
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Publication
35348629 | J:325566
First Author: McAndrews KM
Year: 2022
Journal: Cancer Discov
Title: Identification of Functional Heterogeneity of Carcinoma-Associated Fibroblasts with Distinct IL6-Mediated Therapy Resistance in Pancreatic Cancer.
Volume: 12
Issue: 6
Pages: 1580-1597
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Publication
40593675 | J:370197
First Author: Brown ME
Year: 2025
Journal: Nat Commun
Title: Pancreatic islet ?-cell subtypes are derived from biochemically-distinct and nutritionally-regulated islet progenitors.
Volume: 16
Issue: 1
Pages: 5758
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Publication
41324576 | J:389986
   
First Author: Donofrio SG
Year: 2025
Journal: Elife
Title: Cerebellar Purkinje cell stripe patterns reveal a differential vulnerability and resistance to cell loss during normal aging in mice.
Volume: 14
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Publication
37141889 | J:354809
First Author: Wei W
Year: 2023
Journal: Cell Metab
Title: Organism-wide, cell-type-specific secretome mapping of exercise training in mice.
Volume: 35
Issue: 7
Pages: 1261-1279.e11
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- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
23823474 | J:199239
First Author: Magnuson MA
Year: 2013
Journal: Cell Metab
Title: Pancreas-specific Cre driver lines and considerations for their prudent use.
Volume: 18
Issue: 1
Pages: 9-20
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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