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Hits by Pathway

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Hits by Strain

Type Details Score
Protein Coding Gene
MGI:3031088 | Or4a81
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:3030518 | Or56a4
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:3031074 | Or4a68
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
35271760 | J:338999
First Author: O'Brien A
Year: 2022
Journal: Hepatol Commun
Title: FGF1 Signaling Modulates Biliary Injury and Liver Fibrosis in the Mdr2(-/-) Mouse Model of Primary Sclerosing Cholangitis.
Volume: 6
Issue: 7
Pages: 1574-1588
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Publication
31843339 | J:290474
 
First Author: Vargas-Castillo A
Year: 2020
Journal: Metabolism
Title: Angiotensin-(1-7) induces beige fat thermogenesis through the Mas receptor.
Volume: 103
Pages: 154048
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Publication
27715254 | J:240655
First Author: Sahr A
Year: 2016
Journal: Endocrinology
Title: The Angiotensin-(1-7)/Mas Axis Improves Pancreatic β-Cell Function in Vitro and in Vivo.
Volume: 157
Issue: 12
Pages: 4677-4690
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Publication
9751762 | J:50149
First Author: Elefanty AG
Year: 1998
Journal: Proc Natl Acad Sci U S A
Title: Characterization of hematopoietic progenitor cells that express the transcription factor SCL, using a lacZ "knock-in" strategy.
Volume: 95
Issue: 20
Pages: 11897-902
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Publication
28439028 | J:242220
First Author: Ohlen SB
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: BGP-15 prevents the death of neurons in a mouse model of familial dysautonomia.
Volume: 114
Issue: 19
Pages: 5035-5040
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Publication
19996281 | J:155744
First Author: Fan Y
Year: 2010
Journal: Cancer Res
Title: The aryl hydrocarbon receptor functions as a tumor suppressor of liver carcinogenesis.
Volume: 70
Issue: 1
Pages: 212-20
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Publication
27525438 | J:237243
First Author: Achuthan A
Year: 2016
Journal: J Clin Invest
Title: Granulocyte macrophage colony-stimulating factor induces CCL17 production via IRF4 to mediate inflammation.
Volume: 126
Issue: 9
Pages: 3453-66
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Publication
6334807 | J:30789
First Author: Gray PW
Year: 1984
Journal: Nature
Title: Cloning and expression of cDNA for human lymphotoxin, a lymphokine with tumour necrosis activity.
Volume: 312
Issue: 5996
Pages: 721-4
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Publication
25925587 | J:249178
First Author: Fraccaroli A
Year: 2015
Journal: Circ Res
Title: Endothelial alpha-parvin controls integrity of developing vasculature and is required for maintenance of cell-cell junctions.
Volume: 117
Issue: 1
Pages: 29-40
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Publication
21909113 | J:176649
First Author: Guo C
Year: 2011
Journal: Nature
Title: CTCF-binding elements mediate control of V(D)J recombination.
Volume: 477
Issue: 7365
Pages: 424-30
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Publication
8917514 | J:36569
First Author: Chen CK
Year: 1996
Journal: Proc Natl Acad Sci U S A
Title: RGS-r, a retinal specific RGS protein, binds an intermediate conformation of transducin and enhances recycling.
Volume: 93
Issue: 23
Pages: 12885-9
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Publication
16449386 | J:248239
First Author: Cai D
Year: 2006
Journal: Proc Natl Acad Sci U S A
Title: Presenilin-1 uses phospholipase D1 as a negative regulator of beta-amyloid formation.
Volume: 103
Issue: 6
Pages: 1941-6
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Publication
23624931 | J:198821
First Author: Sparmann A
Year: 2013
Journal: EMBO J
Title: The chromodomain helicase Chd4 is required for Polycomb-mediated inhibition of astroglial differentiation.
Volume: 32
Issue: 11
Pages: 1598-612
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Publication
27825441 | J:237506
First Author: Houtz J
Year: 2016
Journal: Dev Cell
Title: Neurotrophin Signaling Is Required for Glucose-Induced Insulin Secretion.
Volume: 39
Issue: 3
Pages: 329-345
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Publication
22314397 | J:323267
 
First Author: Entezari M
Year: 2012
Journal: Mol Med
Title: Inhibition of high-mobility group box 1 protein (HMGB1) enhances bacterial clearance and protects against Pseudomonas Aeruginosa pneumonia in cystic fibrosis.
Volume: 18
Pages: 477-85
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Publication
8577752 | J:41547
First Author: Lombard-Platet G
Year: 1996
Journal: Proc Natl Acad Sci U S A
Title: A close relative of the adrenoleukodystrophy (ALD) gene codes for a peroxisomal protein with a specific expression pattern.
Volume: 93
Issue: 3
Pages: 1265-9
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GO Term
GO:0036177 | filamentous growth of a population of unicellular organisms in response to pH
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Publication
29389974 | J:257581
First Author: Sagner A
Year: 2018
Journal: PLoS Biol
Title: Olig2 and Hes regulatory dynamics during motor neuron differentiation revealed by single cell transcriptomics.
Volume: 16
Issue: 2
Pages: e2003127
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Publication
8855296 | -
First Author: Ahn K
Year: 1996
Journal: Proc Natl Acad Sci U S A
Title: Human cytomegalovirus inhibits antigen presentation by a sequential multistep process.
Volume: 93
Issue: 20
Pages: 10990-5
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Publication
18433302 | J:150241
First Author: Ferlin A
Year: 2008
Journal: J Bone Miner Res
Title: Mutations in the insulin-like factor 3 receptor are associated with osteoporosis.
Volume: 23
Issue: 5
Pages: 683-93
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Publication
1765007 | J:2951
First Author: Hogan A
Year: 1991
Journal: Development
Title: Glucose transporter gene expression in early mouse embryos.
Volume: 113
Issue: 1
Pages: 363-72
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Publication
9107680 | J:39609
First Author: Koch A
Year: 1997
Journal: Mamm Genome
Title: cDNA cloning and chromosomal mapping of mouse fast skeletal muscle troponin T.
Volume: 8
Issue: 5
Pages: 346-8
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Publication
9344676 | J:44020
First Author: Sutton KA
Year: 1997
Journal: Genomics
Title: The rapidly evolving Pem homeobox gene and Agtr2, Ant2, and Lamp2 are closely linked in the proximal region of the mouse X chromosome.
Volume: 45
Issue: 2
Pages: 447-50
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Regulatory Region
MGI:7407247 | Rr327
Type: enhancer
Organism: mouse, laboratory
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Publication
21727904 | J:290338
First Author: Lenzo JC
Year: 2012
Journal: Immunol Cell Biol
Title: Control of macrophage lineage populations by CSF-1 receptor and GM-CSF in homeostasis and inflammation.
Volume: 90
Issue: 4
Pages: 429-40
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Publication
24806796 | -
First Author: Jorgenson MA
Year: 2014
Journal: Mol Microbiol
Title: The bacterial septal ring protein RlpA is a lytic transglycosylase that contributes to rod shape and daughter cell separation in Pseudomonas aeruginosa.
Volume: 93
Issue: 1
Pages: 113-28
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Publication
1846043 | J:10920
First Author: Stephenson DA
Year: 1991
Journal: Proc Natl Acad Sci U S A
Title: Platelet-derived growth factor receptor alpha-subunit gene (Pdgfra) is deleted in the mouse patch (Ph) mutation.
Volume: 88
Issue: 1
Pages: 6-10
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Publication
- | J:203621
     
First Author: Dionne L
Year: 2014
Journal: MGI Direct Data Submission
Title: Brachyury-like 5, a new spontaneous mutation resembling brachyury
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Publication
25908590 | J:222796
 
First Author: Yamagata A
Year: 2015
Journal: Nat Commun
Title: Mechanisms of splicing-dependent trans-synaptic adhesion by PTPδ-IL1RAPL1/IL-1RAcP for synaptic differentiation.
Volume: 6
Pages: 6926
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Publication
23314863 | J:195223
First Author: Werner A
Year: 2013
Journal: Nat Cell Biol
Title: SCFFbxw5 mediates transient degradation of actin remodeller Eps8 to allow proper mitotic progression.
Volume: 15
Issue: 2
Pages: 179-88
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Publication
33823153 | J:308299
 
First Author: Vilalta A
Year: 2021
Journal: J Biol Chem
Title: Wild-type sTREM2 blocks Aβ aggregation and neurotoxicity, but the Alzheimer's R47H mutant increases Aβ aggregation.
Volume: 296
Pages: 100631
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Publication
33990661 | J:314449
First Author: Shrivastava V
Year: 2021
Journal: Sci Rep
Title: Beta cell adaptation to pregnancy requires prolactin action on both beta and non-beta cells.
Volume: 11
Issue: 1
Pages: 10372
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Publication
19808894 | J:164170
First Author: Jager J
Year: 2010
Journal: Diabetes
Title: Tpl2 kinase is upregulated in adipose tissue in obesity and may mediate interleukin-1beta and tumor necrosis factor-{alpha} effects on extracellular signal-regulated kinase activation and lipolysis.
Volume: 59
Issue: 1
Pages: 61-70
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Protein
P15920-2
Organism: Mus musculus/domesticus
Length: 263  
Fragment?: false
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Publication
24216479 | J:204180
First Author: Court H
Year: 2013
Journal: J Clin Invest
Title: Isoprenylcysteine carboxylmethyltransferase deficiency exacerbates KRAS-driven pancreatic neoplasia via Notch suppression.
Volume: 123
Issue: 11
Pages: 4681-94
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Publication
30228296 | J:283080
First Author: Chiou SH
Year: 2018
Journal: Sci Rep
Title: Hmga2 is dispensable for pancreatic cancer development, metastasis, and therapy resistance.
Volume: 8
Issue: 1
Pages: 14008
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Publication
23828199 | J:344926
First Author: Kawauchi J
Year: 2013
Journal: J Biol Chem
Title: Transcriptional properties of mammalian elongin A and its role in stress response.
Volume: 288
Issue: 34
Pages: 24302-15
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Publication
22326582 | J:181313
First Author: Vijayanand P
Year: 2012
Journal: Immunity
Title: Interleukin-4 production by follicular helper T cells requires the conserved Il4 enhancer hypersensitivity site V.
Volume: 36
Issue: 2
Pages: 175-87
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Publication
21847099 | J:177194
First Author: Pekowska A
Year: 2011
Journal: EMBO J
Title: H3K4 tri-methylation provides an epigenetic signature of active enhancers.
Volume: 30
Issue: 20
Pages: 4198-210
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Publication
20980074 | J:188224
First Author: Ternianov A
Year: 2012
Journal: Neurobiol Aging
Title: Overexpression of CB2 cannabinoid receptors results in neuroprotection against behavioral and neurochemical alterations induced by intracaudate administration of 6-hydroxydopamine.
Volume: 33
Issue: 2
Pages: 421.e1-16
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Publication
- | J:95724
     
First Author: Song A
Year: 2005
Journal: MGI Direct Data Submission
Title: Major Elements of Prediabetes Progression in NOD Mice are Islet-Driven Local Events
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Publication
18514192 | J:138022
First Author: Hayashi A
Year: 2008
Journal: Exp Neurol
Title: Treatment modality affects allograft-derived Schwann cell phenotype and myelinating capacity.
Volume: 212
Issue: 2
Pages: 324-36
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Publication
36609505 | J:337511
First Author: Irazoki A
Year: 2023
Journal: Nat Commun
Title: Disruption of mitochondrial dynamics triggers muscle inflammation through interorganellar contacts and mitochondrial DNA mislocation.
Volume: 14
Issue: 1
Pages: 108
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Publication
22613767 | J:188074
First Author: Rodríguez-Enfedaque A
Year: 2012
Journal: Biochim Biophys Acta
Title: zVAD-fmk upregulates caspase-9 cleavage and activity in etoposide-induced cell death of mouse embryonic fibroblasts.
Volume: 1823
Issue: 8
Pages: 1343-52
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Publication
25535338 | J:218163
First Author: Jin S
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: Gas1 is a receptor for sonic hedgehog to repel enteric axons.
Volume: 112
Issue: 1
Pages: E73-80
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Publication
17194759 | J:119082
First Author: Schuster-Gossler K
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: Premature myogenic differentiation and depletion of progenitor cells cause severe muscle hypotrophy in Delta1 mutants.
Volume: 104
Issue: 2
Pages: 537-42
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Publication
31601784 | J:282096
First Author: Duan Y
Year: 2019
Journal: Cell Death Dis
Title: Heat shock protein 60 regulates yolk sac erythropoiesis in mice.
Volume: 10
Issue: 10
Pages: 766
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Publication
26525672 | J:227703
First Author: Garside VC
Year: 2015
Journal: Development
Title: SOX9 modulates the expression of key transcription factors required for heart valve development.
Volume: 142
Issue: 24
Pages: 4340-50
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Publication
17108083 | -
First Author: Unk I
Year: 2006
Journal: Proc Natl Acad Sci U S A
Title: Human SHPRH is a ubiquitin ligase for Mms2-Ubc13-dependent polyubiquitylation of proliferating cell nuclear antigen.
Volume: 103
Issue: 48
Pages: 18107-12
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Publication
8159699 | J:42289
First Author: Martasek P
Year: 1994
Journal: Proc Natl Acad Sci U S A
Title: Molecular cloning, sequencing, and functional expression of a cDNA encoding human coproporphyrinogen oxidase.
Volume: 91
Issue: 8
Pages: 3024-8
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Publication
1711207 | J:20286
First Author: Brannan CI
Year: 1991
Journal: Proc Natl Acad Sci U S A
Title: Steel-Dickie mutation encodes a c-kit ligand lacking transmembrane and cytoplasmic domains.
Volume: 88
Issue: 11
Pages: 4671-4
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Publication
9275201 | J:42819
First Author: Tsirka SE
Year: 1997
Journal: Proc Natl Acad Sci U S A
Title: Neuronal death in the central nervous system demonstrates a non-fibrin substrate for plasmin.
Volume: 94
Issue: 18
Pages: 9779-81
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Publication
11891296 | J:126524
First Author: Wagner DH Jr
Year: 2002
Journal: Proc Natl Acad Sci U S A
Title: Expression of CD40 identifies a unique pathogenic T cell population in type 1 diabetes.
Volume: 99
Issue: 6
Pages: 3782-7
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Publication
29358403 | J:258288
First Author: Lerdkrai C
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: Intracellular Ca2+ stores control in vivo neuronal hyperactivity in a mouse model of Alzheimer's disease.
Volume: 115
Issue: 6
Pages: E1279-E1288
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Publication
2440031 | J:118310
First Author: Gunning P
Year: 1987
Journal: Proc Natl Acad Sci U S A
Title: A human beta-actin expression vector system directs high-level accumulation of antisense transcripts.
Volume: 84
Issue: 14
Pages: 4831-5
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Publication
16492728 | J:107176
First Author: Varga R
Year: 2006
Journal: Proc Natl Acad Sci U S A
Title: Progressive vascular smooth muscle cell defects in a mouse model of Hutchinson-Gilford progeria syndrome.
Volume: 103
Issue: 9
Pages: 3250-5
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Publication
12629219 | J:82744
First Author: Hinds HL
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Essential function of alpha-calcium/calmodulin-dependent protein kinase II in neurotransmitter release at a glutamatergic central synapse.
Volume: 100
Issue: 7
Pages: 4275-80
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Publication
31772018 | J:286091
First Author: Svoboda DS
Year: 2019
Journal: Proc Natl Acad Sci U S A
Title: Human iPSC-derived microglia assume a primary microglia-like state after transplantation into the neonatal mouse brain.
Volume: 116
Issue: 50
Pages: 25293-25303
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Publication
23308049 | J:310012
First Author: Ceteci F
Year: 2012
Journal: Neoplasia
Title: E-cadherin controls bronchiolar progenitor cells and onset of preneoplastic lesions in mice.
Volume: 14
Issue: 12
Pages: 1164-77
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Publication
22529362 | J:184816
First Author: Crook ZR
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Dysregulation of dopamine receptor D2 as a sensitive measure for Huntington disease pathology in model mice.
Volume: 109
Issue: 19
Pages: 7487-92
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Publication
25180604 | J:217638
First Author: Dahdah A
Year: 2014
Journal: J Clin Invest
Title: Mast cells aggravate sepsis by inhibiting peritoneal macrophage phagocytosis.
Volume: 124
Issue: 10
Pages: 4577-89
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Publication
21124852 | J:167317
First Author: Sahaboglu A
Year: 2010
Journal: PLoS One
Title: PARP1 gene knock-out increases resistance to retinal degeneration without affecting retinal function.
Volume: 5
Issue: 11
Pages: e15495
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Publication
20182448 | J:160092
First Author: Ogawa A
Year: 2010
Journal: J Invest Dermatol
Title: The differential role of L-selectin and ICAM-1 in Th1-type and Th2-type contact hypersensitivity.
Volume: 130
Issue: 6
Pages: 1558-70
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Publication
16461740 | J:107551
First Author: Kawasuji A
Year: 2006
Journal: J Leukoc Biol
Title: L-selectin and intercellular adhesion molecule-1 regulate the development of Concanavalin A-induced liver injury.
Volume: 79
Issue: 4
Pages: 696-705
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Publication
31849960 | J:297841
 
First Author: Saadalla A
Year: 2019
Journal: Front Immunol
Title: Cell Intrinsic Deregulated ß-Catenin Signaling Promotes Expansion of Bone Marrow Derived Connective Tissue Type Mast Cells, Systemic Inflammation, and Colon Cancer.
Volume: 10
Pages: 2777
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Publication
36264429 | J:347325
First Author: Heinze A
Year: 2022
Journal: Cell Mol Life Sci
Title: Functional interdependence of the actin regulators CAP1 and cofilin1 in control of dendritic spine morphology.
Volume: 79
Issue: 11
Pages: 558
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Publication
28882901 | J:253491
First Author: Thomas A
Year: 2017
Journal: Diabetes
Title: Chronic Intermittent Hypoxia Impairs Insulin Sensitivity but Improves Whole-Body Glucose Tolerance by Activating Skeletal Muscle AMPK.
Volume: 66
Issue: 12
Pages: 2942-2951
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Publication
23800510 | J:210411
 
First Author: Bühler A
Year: 2013
Journal: Exp Eye Res
Title: Cathepsin proteases promote angiogenic sprouting and laser-induced choroidal neovascularisation in mice.
Volume: 115
Pages: 73-8
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Publication
24662765 | J:214782
First Author: Uhmann A
Year: 2014
Journal: J Invest Dermatol
Title: DMBA/TPA treatment is necessary for BCC formation from patched deficient epidermal cells in Ptch(flox/flox)CD4Cre(+/-) mice.
Volume: 134
Issue: 10
Pages: 2620-2629
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Publication
23580568 | J:198475
First Author: Abot A
Year: 2013
Journal: Endocrinology
Title: The AF-1 activation function of estrogen receptor α is necessary and sufficient for uterine epithelial cell proliferation in vivo.
Volume: 154
Issue: 6
Pages: 2222-33
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Publication
17456788 | J:122399
First Author: Sainsbury A
Year: 2007
Journal: Mol Endocrinol
Title: Dynorphin knockout reduces fat mass and increases weight loss during fasting in mice.
Volume: 21
Issue: 7
Pages: 1722-35
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Publication
16162938 | J:101056
First Author: Bolis A
Year: 2005
Journal: J Neurosci
Title: Loss of Mtmr2 phosphatase in Schwann cells but not in motor neurons causes Charcot-Marie-Tooth type 4B1 neuropathy with myelin outfoldings.
Volume: 25
Issue: 37
Pages: 8567-77
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Publication
33596089 | J:302344
   
First Author: Raya-Sandino A
Year: 2021
Journal: Mol Biol Cell
Title: Regulation of Intestinal Epithelial Intercellular Adhesion and Barrier Function by Desmosomal Cadherin Desmocollin-2.
Pages: mbcE20120775
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Publication
31263146 | J:285997
First Author: Crotti A
Year: 2019
Journal: Sci Rep
Title: BIN1 favors the spreading of Tau via extracellular vesicles.
Volume: 9
Issue: 1
Pages: 9477
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Publication
36166953 | J:330386
 
First Author: Sanbe A
Year: 2022
Journal: Biochem Biophys Res Commun
Title: Modification of cardiac disease by transgenically altered histone deacetylase 6.
Volume: 631
Pages: 48-54
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Publication
15920036 | J:128554
First Author: Trion A
Year: 2005
Journal: Arterioscler Thromb Vasc Biol
Title: No effect of C-reactive protein on early atherosclerosis development in apolipoprotein E*3-leiden/human C-reactive protein transgenic mice.
Volume: 25
Issue: 8
Pages: 1635-40
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Publication
21289195 | J:252960
First Author: Tozzi A
Year: 2011
Journal: J Neurosci
Title: The distinct role of medium spiny neurons and cholinergic interneurons in the Dâ‚‚/Aâ‚‚A receptor interaction in the striatum: implications for Parkinson's disease.
Volume: 31
Issue: 5
Pages: 1850-62
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Publication
34672987 | J:321259
First Author: Domingo A
Year: 2021
Journal: Am J Hum Genet
Title: Dystonia-specific mutations in THAP1 alter transcription of genes associated with neurodevelopment and myelin.
Volume: 108
Issue: 11
Pages: 2145-2158
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Publication
18775308 | J:188627
First Author: Kaser A
Year: 2008
Journal: Cell
Title: XBP1 links ER stress to intestinal inflammation and confers genetic risk for human inflammatory bowel disease.
Volume: 134
Issue: 5
Pages: 743-56
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Publication
28758999 | J:258017
First Author: Caccamo A
Year: 2017
Journal: Nat Neurosci
Title: Necroptosis activation in Alzheimer's disease.
Volume: 20
Issue: 9
Pages: 1236-1246
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Publication
28902427 | J:318903
First Author: Wree A
Year: 2018
Journal: Hepatology
Title: NLRP3 inflammasome driven liver injury and fibrosis: Roles of IL-17 and TNF in mice.
Volume: 67
Issue: 2
Pages: 736-749
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Publication
25646416 | J:220012
First Author: Keskin DB
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: Physical detection of influenza A epitopes identifies a stealth subset on human lung epithelium evading natural CD8 immunity.
Volume: 112
Issue: 7
Pages: 2151-6
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Publication
15919816 | J:99731
First Author: Ruppel KM
Year: 2005
Journal: Proc Natl Acad Sci U S A
Title: Essential role for Galpha13 in endothelial cells during embryonic development.
Volume: 102
Issue: 23
Pages: 8281-6
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Publication
14597716 | J:128779
First Author: Wolfsgruber W
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: A proatherogenic role for cGMP-dependent protein kinase in vascular smooth muscle cells.
Volume: 100
Issue: 23
Pages: 13519-24
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