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Search results 3401 to 3500 out of 3880 for Col2a1

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Type Details Score
Publication
First Author: Wang H
Year: 2019
Journal: J Cell Physiol
Title: Chondrocyte mTORC1 activation stimulates miR-483-5p via HDAC4 in osteoarthritis progression.
Volume: 234
Issue: 3
Pages: 2730-2740
Publication  
First Author: Mizuno S
Year: 2020
Journal: Bone
Title: ADAM10 is indispensable for longitudinal bone growth in mice.
Volume: 134
Pages: 115273
Publication      
First Author: Mamidi MK
Year: 2021
Journal: J Cell Physiol
Title: The transcriptional cofactor Jab1/Cops5 is crucial for BMP-mediated mouse chondrocyte differentiation by repressing p53 activity.
Publication  
First Author: Xing W
Year: 2021
Journal: Cells
Title: Prolyl Hydroxylase Domain-Containing Protein 3 Gene Expression in Chondrocytes Is Not Essential for Bone Development in Mice.
Volume: 10
Issue: 9
Publication
First Author: Ascenzi MG
Year: 2011
Journal: J Theor Biol
Title: Effect of localization, length and orientation of chondrocytic primary cilium on murine growth plate organization.
Volume: 285
Issue: 1
Pages: 147-55
Publication
First Author: Chen CG
Year: 2012
Journal: Arthritis Rheum
Title: Chondrocyte-intrinsic Smad3 represses Runx2-inducible matrix metalloproteinase 13 expression to maintain articular cartilage and prevent osteoarthritis.
Volume: 64
Issue: 10
Pages: 3278-89
Publication
First Author: Bubb K
Year: 2021
Journal: J Biol Chem
Title: Mitochondrial respiratory chain function promotes extracellular matrix integrity in cartilage.
Volume: 297
Issue: 4
Pages: 101224
Publication
First Author: Li Y
Year: 2022
Journal: Cell Death Dis
Title: Mice with Trp53 and Rb1 deficiency in chondrocytes spontaneously develop chondrosarcoma via overactivation of YAP signaling.
Volume: 13
Issue: 6
Pages: 570
Publication  
First Author: Mark PR
Year: 2022
Journal: Cold Spring Harb Mol Case Stud
Title: Autosomal recessive LRP1-related syndrome featuring cardiopulmonary dysfunction, bone dysmorphology, and corneal clouding.
Volume: 8
Issue: 6
Publication
First Author: Yadav PS
Year: 2023
Journal: iScience
Title: Phosphate-induced activation of VEGFR2 leads to caspase-9-mediated apoptosis of hypertrophic chondrocytes.
Volume: 26
Issue: 9
Pages: 107548
Publication  
First Author: Sohn P
Year: 2010
Journal: BMC Dev Biol
Title: Molecular profiling of the developing mouse axial skeleton: a role for Tgfbr2 in the development of the intervertebral disc.
Volume: 10
Pages: 29
Publication
First Author: Cheng S
Year: 2013
Journal: Physiol Genomics
Title: Haploinsufficiency of osterix in chondrocytes impairs skeletal growth in mice.
Volume: 45
Issue: 19
Pages: 917-23
Publication
First Author: Jouan Y
Year: 2022
Journal: Sci Adv
Title: Lin28a induces SOX9 and chondrocyte reprogramming via HMGA2 and blunts cartilage loss in mice.
Volume: 8
Issue: 34
Pages: eabn3106
Publication
First Author: Inuzuka M
Year: 2010
Journal: Endocrinology
Title: C-type natriuretic peptide as a new regulator of food intake and energy expenditure.
Volume: 151
Issue: 8
Pages: 3633-42
Publication
First Author: Fujii T
Year: 2010
Journal: Endocrinology
Title: Circulating C-type natriuretic peptide (CNP) rescues chondrodysplastic CNP knockout mice from their impaired skeletal growth and early death.
Volume: 151
Issue: 9
Pages: 4381-8
Publication
First Author: Yang G
Year: 2008
Journal: Development
Title: PTEN deficiency causes dyschondroplasia in mice by enhanced hypoxia-inducible factor 1alpha signaling and endoplasmic reticulum stress.
Volume: 135
Issue: 21
Pages: 3587-97
Publication
First Author: Kondo E
Year: 2012
Journal: Calcif Tissue Int
Title: Skeletal analysis of the long bone abnormality (lbab/lbab) mouse, a novel chondrodysplastic C-type natriuretic peptide mutant.
Volume: 90
Issue: 4
Pages: 307-18
Publication
First Author: Tsuji T
Year: 2008
Journal: Biochem Biophys Res Commun
Title: Hypomorphic mutation in mouse Nppc gene causes retarded bone growth due to impaired endochondral ossification.
Volume: 376
Issue: 1
Pages: 186-90
Allele
Name: transgene insertion 4, Toshihisa Komori
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
Publication
First Author: Lapveteläinen T
Year: 2002
Journal: Ann Rheum Dis
Title: Lifelong voluntary joint loading increases osteoarthritis in mice housing a deletion mutation in type II procollagen gene, and slightly also in non-transgenic mice.
Volume: 61
Issue: 9
Pages: 810-7
Publication
First Author: Hiltunen A
Year: 1995
Journal: FEBS Lett
Title: Expression of type VI, IX and XI collagen genes and alternative splicing of type II collagen transcripts in fracture callus tissue in mice.
Volume: 364
Issue: 2
Pages: 171-4
Strain
Attribute String: congenic, mutant strain, transgenic
Allele
Name: transgene insertion KA3, Susan Mackem
Allele Type: Transgenic
Attribute String: Inducible, Recombinase
Strain
Attribute String: coisogenic, mutant strain, transgenic
Publication  
First Author: Ni W
Year: 2023
Journal: Redox Biol
Title: An inducible long noncoding RNA, LncZFHX2, facilitates DNA repair to mediate osteoarthritis pathology.
Volume: 66
Pages: 102858
Publication  
First Author: Qian Z
Year: 2023
Journal: Int Immunopharmacol
Title: Cartilage-specific deficiency of clock gene Bmal1 accelerated articular cartilage degeneration in osteoarthritis by up-regulation of mTORC1 signaling.
Volume: 115
Pages: 109692
Publication
First Author: Li X
Year: 2022
Journal: Int J Biol Sci
Title: Effect Of XBP1 Deficiency In Cartilage On The Regulatory Network Of LncRNA/circRNA-miRNA-mRNA.
Volume: 18
Issue: 1
Pages: 315-330
Publication
First Author: Wen X
Year: 2016
Journal: J Biol Chem
Title: Chondrocyte FGFR3 Regulates Bone Mass by Inhibiting Osteogenesis.
Volume: 291
Issue: 48
Pages: 24912-24921
Strain
Attribute String: congenic, mutant strain, chemically induced mutation
Strain
Attribute String: chemically induced mutation, mutant stock
Strain
Attribute String: chemically induced mutation, congenic, mutant strain
Strain
Attribute String: Not specified
Publication
First Author: Posey KL
Year: 2009
Journal: Am J Pathol
Title: An inducible cartilage oligomeric matrix protein mouse model recapitulates human pseudoachondroplasia phenotype.
Volume: 175
Issue: 4
Pages: 1555-63
Publication  
First Author: Coustry F
Year: 2018
Journal: Matrix Biol
Title: Mutant cartilage oligomeric matrix protein (COMP) compromises bone integrity, joint function and the balance between adipogenesis and osteogenesis.
Volume: 67
Pages: 75-89
Publication
First Author: Posey KL
Year: 2012
Journal: Am J Pathol
Title: Chop (Ddit3) is essential for D469del-COMP retention and cell death in chondrocytes in an inducible transgenic mouse model of pseudoachondroplasia.
Volume: 180
Issue: 2
Pages: 727-37
Allele
Name: transgene insertion 1, George Bou-Gharios
Allele Type: Transgenic
Attribute String: Inducible, Recombinase, Reporter
Allele
Name: transgene insertion 1, David Butler
Allele Type: Transgenic
Attribute String: Reporter
Allele
Name: transgene insertion 1, William A Horton
Allele Type: Transgenic
Attribute String: Reporter
Allele
Name: transgene insertion H, Noriaki Ono
Allele Type: Transgenic
Attribute String: Transactivator
Strain
Attribute String: congenic, mutant strain, transgenic
Allele
Name: transgene insertion, Andrzej Fertala
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
Genotype
Symbol: Ctnnb1/Ctnnb1 Tg(Col2a1-cre)1Bhr/?
Background: involves: 129S6/SvEvTac * C57BL/6
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Sox9/Sox9<+> Tg(Col2a1-cre)1Bhr/?
Background: involves: 129S7/SvEvBrd * C57BL/6 * SJL
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Sox9/Sox9 Tg(Col2a1-cre)1Bhr/?
Background: involves: 129S7/SvEvBrd * C57BL/6 * SJL
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Fosl2/Fosl2 Tg(COL2A1-cre)1Wag/?
Background: involves: 129P2/OlaHsd * C57BL/6 * CBA
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Nppc/Nppc Tg(Col2a1-Nppc)1Yog/?
Background: either: 129X1/SvJ or (involves: 129 * C57BL/6J)
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Tg(Col2a1-Hdac4)1Eno/?
Background: Not Specified
Zygosity: ot
Has Mutant Allele: true
Genotype
Symbol: Fgfr3/Fgfr3<+> Tg(Col2a1-cre)1Bhr/?
Background: involves: 129S6/SvEvTac * C57BL/6 * NIH Black Swiss * SJL
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Ptch1/Ptch1 Tg(Col2a1-cre)1Bhr/?
Background: involves: C57BL/6 * SJL
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Sox9/Sox9 Tg(Col2a1-cre)1Bhr/?
Background: involves: 129P2/OlaHsd * C57BL/6 * SJL
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Sox9/Sox9<+> Tg(Col2a1-cre)1Bhr/?
Background: involves: 129P2/OlaHsd * C57BL/6 * SJL
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Tg(Col2a1-cre/ERT)KA3Smac/?
Background: involves: FVB/N
Zygosity: ot
Has Mutant Allele: true
Genotype
Symbol: Tg(Col2a1-cre/ERT)KA3Smac/Tg(Col2a1-cre/ERT)KA3Smac
Background: involves: FVB/N
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Mef2c/Mef2c Tg(Col2a1-cre)1Bhr/?
Background: involves: 129S/SvEv * 129S7/SvEvBrd * C57BL/6 * SJL
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Mef2c/Mef2c Mef2d/Mef2d Tg(Col2a1-cre)1Bhr/?
Background: involves: 129S/SvEv * C57BL/6 * SJL
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Tg(Col2a1-Mef2c/en)1Eno/?
Background: Not Specified
Zygosity: ot
Has Mutant Allele: true
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Col2a1-cre)1Bhr/?
Background: involves: 129S7/SvEvBrd * C57BL/6 * SJL
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Pten/Pten Tg(Col2a1-cre)1Xya/?
Background: involves: 129P2/OlaHsd
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Mbtps1/Mbtps1 Tg(Col2a1-cre)1Bhr/?
Background: involves: 129S6/SvEvTac * C57BL/6 * SJL
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Col2a1/Col2a1<+>
Background: either: C3H.Cg-Col2a1/H or (involves: C3H/HeH * C57BL/6J)
Zygosity: ht
Has Mutant Allele: true
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Col2a1-cre)1Bhr/?
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * ICR * SJL
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Smad1/Smad1 Tg(Col2a1-cre)1Bhr/?
Background: involves: BALB/cJ * C57 * C57BL/6 * SJL
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Amer1/? Tg(Col2a1-cre)1Bhr/?
Background: involves: 129S4/SvJae * C57BL/6 * SJL
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Casr/Casr Tg(Col2a1-cre)1Bhr/?
Background: involves: 129S4/SvJae * C57BL/6 * SJL
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Reck/Reck Tg(Col2a1-cre)1Bhr/?
Background: involves: 129P2/OlaHsd * C57BL/6 * FVB/N * SJL
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Col2a1/Col2a1
Background: involves: C3H/HeH * C57BL/6J
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Ndrg2/Ndrg2 Tg(Col2a1-cre)1Bhr/?
Background: involves: 129S/SvEv * C57BL/6 * SJL
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Sp7/Sp7 Tg(Col2a1-cre)1Bhr/?
Background: involves: C57BL * C57BL/6 * CBA/JNCrlj * SJL
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Tg(CAG-cat,-Twist1)1Dbsp/? Tg(Col2a1-cre)1Bhr/?
Background: involves: C57BL/6 * FVB * SJL
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Serpinh1/Serpinh1 Tg(Col2a1-cre)1Bhr/?
Background: involves: 129S6/SvEvTac * C57BL/6 * C57BL/6J * SJL
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Ntrk2/Ntrk2 Tg(Col2a1-cre)1Bhr/?
Background: involves: 129 * C57BL/6 * SJL
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Mapk14/Mapk14 Tg(Col2a1-cre)1Bhr/?
Background: involves: C57BL/6 * SJL
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Idh1/Idh1<+> Tg(Col2a1-cre)1Bhr/?
Background: involves: C57BL/6 * SJL
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Fermt2/Fermt2 Tg(Col2a1-cre)1Bhr/?
Background: B6.Cg-Fermt2 Tg(Col2a1-cre)1Bhr
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Pbxip1/Pbxip1 Tg(Col2a1-cre/ERT)KA3Smac/?
Background: involves: FVB/N
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Adamts17/Adamts17 Tg(Col2a1-cre)1Bhr/?
Background: involves: C57BL/6 * SJL
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Nppc/Nppc Tg(Col2a1-Nppc)1Yog/?
Background: involves: C57BL/6J * PL/J
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Mbtps1/Mbtps1 Tg(Col2a1-cre)1Bhr/?
Background: involves: 129S6/SvEvTac
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Sp7/Sp7 Tg(Col2a1-cre)1Bhr/?
Background: involves: 129S7/SvEvBrd * C57BL/6 * SJL
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Sp7/Sp7<+> Tg(Col2a1-cre)1Bhr/?
Background: involves: 129S7/SvEvBrd * C57BL/6 * SJL
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Has2/Has2 Tg(Col2a1-cre)1Bhr/?
Background: involves: 129X1/SvJ * C57BL/6 * SJL
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Tgfbr2/Tgfbr2 Tg(Col2a1-cre)1Bhr/?
Background: involves: 129S6/SvEvTac * C57BL/6 * SJL
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Cops5/Cops5 Tg(Col2a1-cre)1Bhr/?
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL
Zygosity: cn
Has Mutant Allele: true
Publication
First Author: Dudley AC
Year: 2008
Journal: Cancer Cell
Title: Calcification of multipotent prostate tumor endothelium.
Volume: 14
Issue: 3
Pages: 201-11
Publication
First Author: Winterpacht A
Year: 1993
Journal: Nat Genet
Title: Kniest and Stickler dysplasia phenotypes caused by collagen type II gene (COL2A1) defect.
Volume: 3
Issue: 4
Pages: 323-6
Publication
First Author: Wang W
Year: 2016
Journal: PLoS Genet
Title: Smad2 and Smad3 Regulate Chondrocyte Proliferation and Differentiation in the Growth Plate.
Volume: 12
Issue: 10
Pages: e1006352
Publication
First Author: Keller B
Year: 2011
Journal: PLoS One
Title: Interaction of TGFβ and BMP signaling pathways during chondrogenesis.
Volume: 6
Issue: 1
Pages: e16421
Publication
First Author: Li Y
Year: 2011
Journal: Development
Title: Calcium/calmodulin-dependent protein kinase II activity regulates the proliferative potential of growth plate chondrocytes.
Volume: 138
Issue: 2
Pages: 359-70
Publication
First Author: Patra D
Year: 2011
Journal: J Biol Chem
Title: Site-1 protease is essential to growth plate maintenance and is a critical regulator of chondrocyte hypertrophic differentiation in postnatal mice.
Volume: 286
Issue: 33
Pages: 29227-40
Publication
First Author: Wu M
Year: 2014
Journal: Int J Biol Sci
Title: Chondrocyte-specific knockout of Cbfβ reveals the indispensable function of Cbfβ in chondrocyte maturation, growth plate development and trabecular bone formation in mice.
Volume: 10
Issue: 8
Pages: 861-72
Publication
First Author: Lian WS
Year: 2022
Journal: Cell Death Dis
Title: Histone H3K27 demethylase UTX compromises articular chondrocyte anabolism and aggravates osteoarthritic degeneration.
Volume: 13
Issue: 6
Pages: 538
Publication
First Author: Hutchison MR
Year: 2013
Journal: PLoS One
Title: Mice with a conditional deletion of the neurotrophin receptor TrkB are dwarfed, and are similar to mice with a MAPK14 deletion.
Volume: 8
Issue: 6
Pages: e66206
Publication
First Author: Georgieva VS
Year: 2022
Journal: Sci Rep
Title: Ablation of the miRNA cluster 24 in cartilage and osteoblasts impairs bone remodeling.
Volume: 12
Issue: 1
Pages: 9116
Publication
First Author: Oshima Y
Year: 2008
Journal: J Biol Chem
Title: Pivotal role of Bcl-2 family proteins in the regulation of chondrocyte apoptosis.
Volume: 283
Issue: 39
Pages: 26499-508
Publication
First Author: Swarnkar G
Year: 2014
Journal: PLoS One
Title: Constitutive activation of IKK2/NF-κB impairs osteogenesis and skeletal development.
Volume: 9
Issue: 3
Pages: e91421
Publication
First Author: Wang W
Year: 2019
Journal: Proc Natl Acad Sci U S A
Title: The TGFβ type I receptor TGFβRI functions as an inhibitor of BMP signaling in cartilage.
Volume: 116
Issue: 31
Pages: 15570-15579
Publication
First Author: Bluhm B
Year: 2017
Journal: Development
Title: miR-322 stabilizes MEK1 expression to inhibit RAF/MEK/ERK pathway activation in cartilage.
Volume: 144
Issue: 19
Pages: 3562-3577
Publication
First Author: Hirata M
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: Mutant IDH is sufficient to initiate enchondromatosis in mice.
Volume: 112
Issue: 9
Pages: 2829-34
Publication
First Author: Ford-Hutchinson AF
Year: 2007
Journal: J Bone Miner Res
Title: Inactivation of Pten in osteo-chondroprogenitor cells leads to epiphyseal growth plate abnormalities and skeletal overgrowth.
Volume: 22
Issue: 8
Pages: 1245-59
Publication
First Author: Masuyama R
Year: 2006
Journal: J Clin Invest
Title: Vitamin D receptor in chondrocytes promotes osteoclastogenesis and regulates FGF23 production in osteoblasts.
Volume: 116
Issue: 12
Pages: 3150-9