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Search results 3401 to 3468 out of 3468 for Foxa2

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0.029s
Type Details Score
Genotype
Symbol: Foxa2/Foxa2 Nodal/Nodal<+>
Background: involves: 129S/SvEv * 129S1/Sv * 129X1/SvJ
Zygosity: cx
Has Mutant Allele: true
GXD Expression
Probe: MGI:5588713
Assay Type: Immunohistochemistry
Annotation Date: 2023-07-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3564522
Pattern: Widespread
Stage: TS22
Assay Id: MGI:7510122
Age: embryonic day 14.5
Image: S4D
Note: Expressed in all pancreatic epithelial cells, albeit at much higher levels in beta-cells. Almost complete overlap between Foxa2 and Pdx1 expression. Most of the Pdx1 highly expressed cells did not display the highest levels of Foxa2, indicating that Foxa2 highly positive cells did not correspond to beta-cells.
Specimen Label: S4D
Detected: true
Specimen Num: 1
Allele
Name: transgene insertion, Victor Leung
Allele Type: Transgenic
Attribute String: Recombinase, Reporter
Genotype
Symbol: Foxa2/Foxa2 Tg(Nes-cre)1Wme/?
Background: involves: 129P2/OlaHsd * C57BL/6 * CBA
Zygosity: cn
Has Mutant Allele: true
Publication
First Author: Au TYK
Year: 2020
Journal: Aging Cell
Title: Transformation of resident notochord-descendent nucleus pulposus cells in mouse injury-induced fibrotic intervertebral discs.
Volume: 19
Issue: 11
Pages: e13254
HT Experiment  
Experiment Type: RNA-Seq
Study Type: Baseline
Source: GEO
Genotype
Symbol: Mib1/Mib1 Foxa2/Foxa2<+>
Background: involves: 129P2/OlaHsd * C57BL/6 * SJL
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Hes1/Hes1 Foxa2/Foxa2<+>
Background: involves: 129P2/OlaHsd * C57BL/6 * CBA
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Dll1/Dll1 Foxa2/Foxa2<+>
Background: involves: 129P2/OlaHsd * C57BL/6 * SJL
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Tg(Foxa2/Sox9-cre,-lacZ)#Vleu/?
Background: involves: C57BL/6 * CBA
Zygosity: ot
Has Mutant Allele: true
HT Experiment
Series Id: GSE57809
Experiment Type: RNA-Seq
Study Type: Baseline
Source: ArrayExpress
Publication
First Author: Ong ALC
Year: 2023
Journal: iScience
Title: Acquisition of neural fate by combination of BMP blockade and chromatin modification.
Volume: 26
Issue: 10
Pages: 107887
Publication
First Author: Matsumoto I
Year: 2011
Journal: Nat Neurosci
Title: Skn-1a (Pou2f3) specifies taste receptor cell lineage.
Volume: 14
Issue: 6
Pages: 685-7
Allele
Name: forkhead box A2; targeted mutation 1, Hiroshi Sasaki
Allele Type: Targeted
Attribute String: Inducible, Recombinase
Genotype
Symbol: Gt(ROSA)26Sor/? Foxa2/Foxa2<+>
Background: involves: 129P2/OlaHsd * C57BL/6 * SJL
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: 9030622O22Rik/9030622O22Rik<+> Foxa2/Foxa2<+>
Background: involves: 129P2/OlaHsd * C57BL/6 * CD-1
Zygosity: cx
Has Mutant Allele: true
HT Experiment  
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
Publication
First Author: Kahane N
Year: 2013
Journal: Development
Title: The transition from differentiation to growth during dermomyotome-derived myogenesis depends on temporally restricted hedgehog signaling.
Volume: 140
Issue: 8
Pages: 1740-50
Genotype
Symbol: Foxa2/Foxa2
Background: involves: C57BL/6J * C57BL/6NCrlj * CBA/JNCrlj * ICR
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Foxa2/Foxa2<+>
Background: involves: C57BL/6J * C57BL/6NCrlj * CBA/JNCrlj * ICR
Zygosity: ht
Has Mutant Allele: true
Genotype
Symbol: Foxa2/Foxa2<+> Gt(ROSA)26Sor/Gt(ROSA)26Sor<+>
Background: involves: 129P2/OlaHsd * 129S4/SvJaeSor
Zygosity: cn
Has Mutant Allele: true
Publication
First Author: Rowbotham NJ
Year: 2009
Journal: Blood
Title: Sonic hedgehog negatively regulates pre-TCR-induced differentiation by a Gli2-dependent mechanism.
Volume: 113
Issue: 21
Pages: 5144-56
Publication
First Author: Kumar A
Year: 2007
Journal: Genesis
Title: Transgenic mouse lines expressing Cre recombinase specifically in posterior notochord and notochord.
Volume: 45
Issue: 12
Pages: 729-36
Publication
First Author: Snyder EL
Year: 2013
Journal: Mol Cell
Title: Nkx2-1 represses a latent gastric differentiation program in lung adenocarcinoma.
Volume: 50
Issue: 2
Pages: 185-99
Publication      
First Author: Dhakal P
Year: 2021
Journal: Mol Reprod Dev
Title: Generation and analysis of Prss28 and Prss29 deficient mice using CRISPR-Cas9 genome-editing.
Publication
First Author: Buteau J
Year: 2006
Journal: Diabetes
Title: Transcription factor FoxO1 mediates glucagon-like peptide-1 effects on pancreatic beta-cell mass.
Volume: 55
Issue: 5
Pages: 1190-6
Publication
First Author: Marquardt RM
Year: 2021
Journal: FASEB J
Title: Endometrial epithelial ARID1A is critical for uterine gland function in early pregnancy establishment.
Volume: 35
Issue: 2
Pages: e21209
Publication
First Author: Naruse C
Year: 2007
Journal: Biochem Biophys Res Commun
Title: A novel gene trapping for identifying genes expressed under the control of specific transcription factors.
Volume: 361
Issue: 1
Pages: 109-15
Publication
First Author: Krammer T
Year: 2024
Journal: Dev Cell
Title: Mouse neural tube organoids self-organize floorplate through BMP-mediated cluster competition.
Volume: 59
Issue: 15
Pages: 1940-1953.e10
Publication
First Author: Morrison G
Year: 2016
Journal: EMBO J
Title: Convergence of cMyc and β-catenin on Tcf7l1 enables endoderm specification.
Volume: 35
Issue: 3
Pages: 356-68
Publication
First Author: Kriseman ML
Year: 2023
Journal: Commun Biol
Title: SMAD2/3 signaling in the uterine epithelium controls endometrial cell homeostasis and regeneration.
Volume: 6
Issue: 1
Pages: 261
Publication
First Author: Balaskas N
Year: 2012
Journal: Cell
Title: Gene regulatory logic for reading the Sonic Hedgehog signaling gradient in the vertebrate neural tube.
Volume: 148
Issue: 1-2
Pages: 273-84
Genotype
Symbol: Foxa2/Foxa2<+> Gt(ROSA)26Sor/Gt(ROSA)26Sor<+>
Background: involves: 129S4/SvJaeSor * C57BL/6J * C57BL/6NCrlj * CBA/JNCrlj * ICR
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Tg(CAG-Bgeo/GFP)21Lbe/? Tg(Foxa2/Sox9-cre,-lacZ)#Vleu/?
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA
Zygosity: cn
Has Mutant Allele: true
Publication
First Author: Yoshiba S
Year: 2012
Journal: Science
Title: Cilia at the node of mouse embryos sense fluid flow for left-right determination via Pkd2.
Volume: 338
Issue: 6104
Pages: 226-31
Publication
First Author: Tan Z
Year: 2024
Journal: Cell Rep
Title: Progenitor-like cells contributing to cellular heterogeneity in the nucleus pulposus are lost in intervertebral disc degeneration.
Volume: 43
Issue: 6
Pages: 114342
Publication
First Author: Besnard V
Year: 2010
Journal: Am J Physiol Lung Cell Mol Physiol
Title: Conditional deletion of Abca3 in alveolar type II cells alters surfactant homeostasis in newborn and adult mice.
Volume: 298
Issue: 5
Pages: L646-59
Publication
First Author: Shen W
Year: 2001
Journal: J Biol Chem
Title: Foxa3 (hepatocyte nuclear factor 3gamma ) is required for the regulation of hepatic GLUT2 expression and the maintenance of glucose homeostasis during a prolonged fast.
Volume: 276
Issue: 46
Pages: 42812-7
Publication
First Author: Davé V
Year: 2006
Journal: J Clin Invest
Title: Calcineurin/Nfat signaling is required for perinatal lung maturation and function.
Volume: 116
Issue: 10
Pages: 2597-609
Publication
First Author: Mucenski ML
Year: 2005
Journal: Am J Physiol Lung Cell Mol Physiol
Title: Beta-catenin regulates differentiation of respiratory epithelial cells in vivo.
Volume: 289
Issue: 6
Pages: L971-9
Publication
First Author: Yu X
Year: 2011
Journal: Oncogene
Title: Wnt/β-catenin activation promotes prostate tumor progression in a mouse model.
Volume: 30
Issue: 16
Pages: 1868-79
Publication
First Author: DeGraff DJ
Year: 2014
Journal: Lab Invest
Title: FOXA1 deletion in luminal epithelium causes prostatic hyperplasia and alteration of differentiated phenotype.
Volume: 94
Issue: 7
Pages: 726-39
Publication
First Author: Lappalainen U
Year: 2005
Journal: Am J Respir Cell Mol Biol
Title: Interleukin-1beta causes pulmonary inflammation, emphysema, and airway remodeling in the adult murine lung.
Volume: 32
Issue: 4
Pages: 311-8
Publication
First Author: Spaeth JM
Year: 2015
Journal: Diabetologia
Title: The FOXP1, FOXP2 and FOXP4 transcription factors are required for islet alpha cell proliferation and function in mice.
Volume: 58
Issue: 8
Pages: 1836-44
Publication
First Author: Alten L
Year: 2012
Journal: PLoS One
Title: A novel mammal-specific three partite enhancer element regulates node and notochord-specific Noto expression.
Volume: 7
Issue: 10
Pages: e47785
Publication
First Author: Kikuchi M
Year: 2016
Journal: PLoS One
Title: Crucial Role of Elovl6 in Chondrocyte Growth and Differentiation during Growth Plate Development in Mice.
Volume: 11
Issue: 7
Pages: e0159375
Publication
First Author: Chang HJ
Year: 2018
Journal: PLoS One
Title: Pik3ca is required for mouse uterine gland development and pregnancy.
Volume: 13
Issue: 1
Pages: e0191433
Publication
First Author: Wang P
Year: 2018
Journal: Endocrinology
Title: Generation of Mouse for Conditional Expression of Forkhead Box A2.
Volume: 159
Issue: 4
Pages: 1897-1909
Publication
First Author: Boortz KA
Year: 2016
Journal: Endocrinology
Title: G6PC2 Modulates the Effects of Dexamethasone on Fasting Blood Glucose and Glucose Tolerance.
Volume: 157
Issue: 11
Pages: 4133-4145
Publication  
First Author: Chenery AL
Year: 2021
Journal: Life Sci Alliance
Title: IL-13 deficiency exacerbates lung damage and impairs epithelial-derived type 2 molecules during nematode infection.
Volume: 4
Issue: 8
Publication
First Author: Yin F
Year: 2014
Journal: Mol Cell Biol
Title: LSD1 regulates pluripotency of embryonic stem/carcinoma cells through histone deacetylase 1-mediated deacetylation of histone H4 at lysine 16.
Volume: 34
Issue: 2
Pages: 158-79
Publication
First Author: Belaguli NS
Year: 2012
Journal: PLoS One
Title: Forkhead box protein A2 (FOXA2) protein stability and activity are regulated by sumoylation.
Volume: 7
Issue: 10
Pages: e48019
Publication
First Author: Rausa FM 3rd
Year: 2004
Journal: J Biol Chem
Title: Stability of the hepatocyte nuclear factor 6 transcription factor requires acetylation by the CREB-binding protein coactivator.
Volume: 279
Issue: 41
Pages: 43070-6
Publication
First Author: Lynn FC
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: Sox9 coordinates a transcriptional network in pancreatic progenitor cells.
Volume: 104
Issue: 25
Pages: 10500-5
Publication
First Author: Ohtsubo K
Year: 2011
Journal: Nat Med
Title: Pathway to diabetes through attenuation of pancreatic beta cell glycosylation and glucose transport.
Volume: 17
Issue: 9
Pages: 1067-75
Publication
First Author: Cerrada-Gimenez M
Year: 2012
Journal: Transgenic Res
Title: Altered glucose-stimulated insulin secretion in a mouse line with activated polyamine catabolism.
Volume: 21
Issue: 4
Pages: 843-53
Publication
First Author: Yang D
Year: 2014
Journal: Development
Title: miR-335 promotes mesendodermal lineage segregation and shapes a transcription factor gradient in the endoderm.
Volume: 141
Issue: 3
Pages: 514-25
Publication
First Author: Jimenez FR
Year: 2015
Journal: Int J Dev Biol
Title: Conditional pulmonary over-expression of Claudin 6 during embryogenesis delays lung morphogenesis.
Volume: 59
Issue: 10-12
Pages: 479-85
Publication
First Author: Hall RA
Year: 2016
Journal: Mamm Genome
Title: Exploring multiple quantitative trait loci models of hepatic fibrosis in a mouse intercross.
Volume: 27
Issue: 1-2
Pages: 70-80
Publication  
First Author: Li JH
Year: 2018
Journal: Arch Biochem Biophys
Title: microRNA-141-3p fosters the growth, invasion, and tumorigenesis of cervical cancer cells by targeting FOXA2.
Volume: 657
Pages: 23-30
Publication
First Author: Liu Q
Year: 2021
Journal: J Pathol
Title: Histone demethylase PHF8 drives neuroendocrine prostate cancer progression by epigenetically upregulating FOXA2.
Volume: 253
Issue: 1
Pages: 106-118
Publication  
First Author: Clarke DM
Year: 2023
Journal: J Dev Biol
Title: Decreased Expression of Pulmonary Homeobox NKX2.1 and Surfactant Protein C in Developing Lungs That Over-Express Receptors for Advanced Glycation End-Products (RAGE).
Volume: 11
Issue: 3
Publication
First Author: Lange A
Year: 2012
Journal: Differentiation
Title: Fltp(T2AiCre): a new knock-in mouse line for conditional gene targeting in distinct mono- and multiciliated tissues.
Volume: 83
Issue: 2
Pages: S105-13
Publication
First Author: Gupta A
Year: 2008
Journal: Prostate
Title: Neuroendocrine differentiation in the 12T-10 transgenic prostate mouse model mimics endocrine differentiation of pancreatic beta cells.
Volume: 68
Issue: 1
Pages: 50-60
Publication
First Author: Kropp PA
Year: 2019
Journal: Cell Mol Gastroenterol Hepatol
Title: Regulation of the Pancreatic Exocrine Differentiation Program and Morphogenesis by Onecut 1/Hnf6.
Volume: 7
Issue: 4
Pages: 841-856
Publication
First Author: Sasai N
Year: 2014
Journal: PLoS Biol
Title: Integration of signals along orthogonal axes of the vertebrate neural tube controls progenitor competence and increases cell diversity.
Volume: 12
Issue: 7
Pages: e1001907
Publication
First Author: Kaushik G
Year: 2021
Journal: Oncogene
Title: Selective inhibition of stemness through EGFR/FOXA2/SOX9 axis reduces pancreatic cancer metastasis.
Volume: 40
Issue: 4
Pages: 848-862
Publication
First Author: Au TYK
Year: 2023
Journal: Proc Natl Acad Sci U S A
Title: Hypomorphic and dominant-negative impact of truncated SOX9 dysregulates Hedgehog-Wnt signaling, causing campomelia.
Volume: 120
Issue: 1
Pages: e2208623119