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Search results 3401 to 3500 out of 3880 for Wt1

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Type Details Score
Genotype
Genotype
Symbol: Wt1/Wt1
Background: involves: 129S4/SvJae * C3H * C57BL/6
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Wt1/Wt1
Background: involves: 129S4/SvJae * C57BL/6 * MF1
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Wt1/Wt1
Background: involves: 129S7/SvEvBrd * C57BL/6J
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Wt1/Wt1
Background: involves: 129S7/SvEvBrd * C57BL/6J
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Wt1/Wt1
Background: involves: 129S7/SvEvBrd * C57BL/6
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Wt1/Wt1
Background: involves: 129P2/OlaHsd * C57BL/6 * CD-1
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Wt1/Wt1
Background: involves: 129S4/SvJae
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Wt1/Wt1
Background: involves: 129S4/SvJae
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Wt1/Wt1
Background: involves: 129S7/SvEvBrd * C57BL/6
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Wt1/Wt1
Background: involves: 129S2/SvPas * C57BL/6
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Wtap/Wtap
Background: involves: 129P2/OlaHsd
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Wt1/Wt1
Background: involves: 129P2/OlaHsd * C57BL/6
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Wt1/Wt1
Background: involves: 129S4/SvJae * NMRI
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Wt1/Wt1
Background: involves: 129S4/SvJae
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Wtip/Wtip
Background: C57BL/6N-Wtip/Ucd
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Wt1/Wt1
Background: B6.129S4-Wt1/J
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Wtap/Wtap
Background: involves: 129P2/OlaHsd * C57BL/6J
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Wt1/Wt1
Background: involves: 129S7/SvEvBrd
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Wtap/Wtap
Background: involves: C57BL/6 * C57BL/6N * CBA
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Wt1/Wt1
Background: involves: 129S7/SvEvBrd
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Wt1/Wt1
Background: involves: 129S7/SvEvBrd * C57BL/6 * DBA/2
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Wt1/Wt1
Background: involves: 129S7/SvEvBrd * C57BL/6 * DBA/2
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Wt1/Wt1
Background: involves: 129S4/SvJae
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Wt1/Wt1
Background: involves: 129P2/OlaHsd
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Wt1/?
Background: involves: 129P2/OlaHsd * 129S2/SvPas
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Wt1/Wt1
Background: involves: 129S4/SvJae * C57BL/6 * DBA
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Wt1/Wt1
Background: involves: 129P2/OlaHsd * C57BL/6
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Wt1/Wt1
Background: involves: 129S4/SvJae * MF1
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Wt1/Wt1
Background: involves: 129P2/OlaHsd * C57BL/6 * DBA/2
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Wt1/Wt1
Background: involves: 129S7/SvEvBrd * C57BL/6
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Wtap/Wtap
Background: Not Specified
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Wtap/Wtap
Background: involves: C57BL/6
Zygosity: hm
Has Mutant Allele: true
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Publication
35879451 | J:330601
First Author: Ito-Kureha T
Year: 2022
Journal: Nat Immunol
Title: The function of Wtap in N6-adenosine methylation of mRNAs controls T cell receptor signaling and survival of T cells.
Volume: 23
Issue: 8
Pages: 1208-1221
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Protein Domain
IPR000976 | Wilms_tumour_N
Type: Domain
Description: Wilm's tumour (WT) is an embryonal malignancy of the kidney, affecting around 1 in 10,000 infants. It occurs in both sporadic and hereditary forms. Inactivation of WT1 is one of the causes of Wilm's tumour. Defects in the WT1 gene are also associated with Denys-Drash Syndrome (DDS), which is characterised by typical nephropathy and genital abnormalities. The WT1 gene product shows similarity to the zinc fingers of the mammalian growth regulated EGR1 and EGR2 proteins [, , , ].
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Allele
Tg(WT1)HNdh | MGI:2183705
Name: transgene insertion H, Nicholas D Hastie
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Tg(Wt1-Sox9)92Asc | MGI:3580900
Name: transgene insertion 92, Andreas Schedl
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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HT Experiment
GSE64063 | Genome-wide analysis of WT1-controlled gene expression in podocytes
Series Id: E-GEOD-64063
Experiment Type: RNA-Seq
Study Type: Baseline
Source: GEO
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HT Experiment
GSE6700 | comparison of gene expression in urogenital ridges of Wt1-/- and +/+ E11.5 mouse embryos
 
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: GEO
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HT Experiment
E-MEXP-3428 | Gene expression profiles of Foxa1 and Foxa2 single and double mutants in embryonic mouse liver
 
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
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HT Experiment
E-MTAB-11003 | RNA-seq of Mtfp1 KO and WT mice at the pre-symptomatic stage and at the onset of dilated cardiomyopathy
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: ArrayExpress
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Publication
20561531 | J:204643
First Author: Filippakopoulos P
Year: 2010
Journal: J Mol Biol
Title: Structural basis for Par-4 recognition by the SPRY domain- and SOCS box-containing proteins SPSB1, SPSB2, and SPSB4.
Volume: 401
Issue: 3
Pages: 389-402
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DO Term
DOID:3764 | Denys-Drash syndrome
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DO Term
DOID:0050438 | Frasier syndrome
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Publication
16369487 | J:245316
First Author: Masters SL
Year: 2006
Journal: Nat Struct Mol Biol
Title: The SPRY domain of SSB-2 adopts a novel fold that presents conserved Par-4-binding residues.
Volume: 13
Issue: 1
Pages: 77-84
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Publication
- | J:337787
First Author: Wang Y
Year: 2022
Journal: Life Metabolism
Title: WTAP regulates postnatal development of brown adipose tissue by stabilizing METTL3 in mice.
Volume: 1
Issue: 3
Pages: 270-284
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Publication
34471108 | J:310403
First Author: Hoefig KP
Year: 2021
Journal: Nat Commun
Title: Defining the RBPome of primary T helper cells to elucidate higher-order Roquin-mediated mRNA regulation.
Volume: 12
Issue: 1
Pages: 5208
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Protein Domain
IPR017987 | Wilms_tumour
Type: Family
Description: Wilm's tumour (WT) is an embryonal malignancy of the kidney, affecting around 1 in 10,000 infants. It occurs in both sporadic and hereditary forms. Inactivation of WT1 is one of the causes of Wilm's tumour. Defects in the WT1 gene are also associated with Denys-Drash Syndrome (DDS), which is characterised by typical nephropathy and genital abnormalities. The WT1 gene product shows similarity to the zinc fingers of the mammalian growth regulated EGR1 and EGR2 proteins [, , , ].This entry represents a Wilm's tumour protein.
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Wt1/Wt1<+>
Background: involves: 129S6/SvEvTac * C57BL/6NCrl
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Wt1/Wt1<+>
Background: involves: 129S7/SvEvBrd * C57BL/6
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Wt1/Wt1<+>
Background: involves: 129S7/SvEvBrd * C57BL/6
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Wt1/Wt1<+>
Background: involves: 129S7/SvEvBrd * C57BL/6
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Wt1/Wt1<+>
Background: involves: 129S2/SvPas * C57BL/6
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Wt1/Wt1<+>
Background: involves: 129S2/SvPas * C57BL/6 * SJL
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Wt1/Wt1 Tg(Gata4*G2-cre)#Roja/?
Background: involves: 129P2/OlaHsd
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Wt1/Wt1 Tg(Tek-cre/ERT2)1Arnd/?
Background: involves: 129P2/OlaHsd * C57BL/6 * DBA/2
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Wtip/Wtip<+>
Background: B6.129P2-Wtip
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Wtip/Wtip<+>
Background: FVB.129P2(B6)-Wtip
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Wt1/Wt1<+>
Background: involves: 129P2/OlaHsd * C57BL/6 * CD-1
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Wt1/Wt1<+>
Background: B6.129S4-Wt1/J
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Wtap/Wtap<+>
Background: involves: 129P2/OlaHsd * C57BL/6J
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Wt1/Wt1<+>
Background: involves: 129S4/SvJae * C57BL/6
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(KRT14-cre)1Amc/? Wtap/Wtap
Background: involves: C57BL/6 * C57BL/6N * CBA
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Wt1/Wt1<+>
Background: B6.Cg-Wt1 Chr Y
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Wtip/Wtip<+>
Background: C57BL/6N-Wtip/Ucd
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Wt1/Wt1<+>
Background: involves: 129S4/SvJae * NMRI
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Wt1/Wt1<+>
Background: B6.Cg-Wt1 Wnt4 Chr Y
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Wt1/Wt1<+>
Background: involves: 129S4/SvJae * C57BL/6
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Wt1/Wt1<+>
Background: involves: 129S2/SvPas
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Wtap/Wtap<+>
Background: involves: 129P2/OlaHsd
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Wt1/Wt1<+>
Background: B6.Cg-Wt1
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Wt1/Wt1
Background: involves: 129S7/SvEvBrd
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Wt1/Wt1<+>
Background: involves: 129S2/SvPas
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Wt1/Wt1<+>
Background: involves: 129S4/SvJae * MF1
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Wt1/Wt1<+>
Background: involves: 129S2/SvPas * FVB/NCrl
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Wt1/Wt1<+>
Background: involves: 129S4/SvJae * C57BL/6 * DBA
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Wt1/Wt1 Tg(Nes-cre)1Kln/?
Background: involves: 129P2/OlaHsd * C57BL/6 * SJL
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(Tnnt2-cre)5Blh/? Wt1/Wt1
Background: involves: 129P2/OlaHsd * C57BL/6 * DBA/2
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(Nes-cre)1Kln/? Wt1/Wt1
Background: involves: 129S7/SvEvBrd * C57BL/6 * SJL
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(Ins2-cre)23Herr/? Wtap/Wtap
Background: involves: C57BL/6J * CBA/J
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Wt1/Wt1<+>
Background: involves:129S4/SvJae * ICR
Zygosity: ht
Has Mutant Allele: true
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Allele
Tg(WT1)WANdh | MGI:2183654
Name: transgene insertion WA, Nicholas D Hastie
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Publication
11431689 | J:76138
First Author: Vidal VP
Year: 2001
Journal: Nat Genet
Title: Sox9 induces testis development in XX transgenic mice.
Volume: 28
Issue: 3
Pages: 216-7
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Allele
Tg(Wt1-EGFP/cre)1Akis | MGI:5002800
Name: transgene insertion 1, Andreas Kispert
Allele Type: Transgenic
Attribute String: Recombinase
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Allele
Tg(Wt1-cre)#Jbeb | MGI:5308608
Name: transgene insertion, John Burch
Allele Type: Transgenic
Attribute String: Recombinase
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Publication
2154702 | -
First Author: Gessler M
Year: 1990
Journal: Nature
Title: Homozygous deletion in Wilms tumours of a zinc-finger gene identified by chromosome jumping.
Volume: 343
Issue: 6260
Pages: 774-8
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Publication
17909014 | J:131451
First Author: Ayyanathan K
Year: 2007
Journal: Cancer Res
Title: The Ajuba LIM domain protein is a corepressor for SNAG domain mediated repression and participates in nucleocytoplasmic Shuttling.
Volume: 67
Issue: 19
Pages: 9097-106
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Publication
19785987 | J:155130
First Author: van Wijk NV
Year: 2009
Journal: Biochem Biophys Res Commun
Title: The LIM domain protein Wtip interacts with the receptor tyrosine kinase Ror2 and inhibits canonical Wnt signalling.
Volume: 390
Issue: 2
Pages: 211-6
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Publication
20616046 | J:162406
First Author: James V
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: LIM-domain proteins, LIMD1, Ajuba, and WTIP are required for microRNA-mediated gene silencing.
Volume: 107
Issue: 28
Pages: 12499-504
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Publication
37777158 | J:342351
First Author: Li X
Year: 2023
Journal: J Biol Chem
Title: Hepatocyte-specific Wtap deficiency promotes hepatocellular carcinoma by activating GRB2-ERK depending on downregulation of proteasome-related genes.
Volume: 299
Issue: 11
Pages: 105301
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HT Experiment
E-GEOD-18358 | Transcription profiling of mouse glomeruli from a model of Denys-Drash Syndrome
Series Id: GSE18358
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
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Genotype
Genotype
Symbol: Wt1/Wt1 Tg(tetO-cre)LC1Bjd/? Tg(NPHS2-rtTA2*M2)1Jbk/?
Background: involves: BALB/c * C57BL/6 * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Wt1/Wt1
Background: involves: 129S4/SvJae * C57BL/6
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tek/Tek<+> Wt1/Wt1<+>
Background: involves: 129S6/SvEvTac * C57BL/6NCrl
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Kdr/Kdr Tek/Tek<+> Wt1/Wt1<+>
Background: involves: 129 * C57BL/6NCrl
Zygosity: cn
Has Mutant Allele: true
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Allele
Tg(LRRK2)WT1Mjfa | MGI:4460657
Name: transgene insertion WT1, Matthew Farrer
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
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Allele
Ewsr1<tm3(WT1)Sblee> | MGI:5638895
Name: Ewing sarcoma breakpoint region 1; targeted mutation 3, Sean Lee
Allele Type: Targeted
Attribute String: Conditional ready, Inserted expressed sequence, Null/knockout
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Genotype
Genotype
Symbol: Sox9/Sox9 Tg(WT1-cre)1Asc/?
Background: involves: 129S7/SvEvBrd * C57BL/6 * CBA
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Kdr/Kdr<+> Tek/Tek<+> Wt1/Wt1<+>
Background: involves: 129 * C57BL/6NCrl
Zygosity: cn
Has Mutant Allele: true
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HT Experiment
E-MTAB-5812 | RNA-seq of BALB/cJ-Ppp1r13lwa3/J (wa3) mouse hearts vs BALB/C wildtype mice aged 7 weeks and 12 weeks mice, as well as lipopolysaccharide treatment for 12-week-old mice
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: ArrayExpress
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Strain
MGI:7525422 | B6.Cg-Wt1<tm1Jae> Wnt4<tm1Amc> Chr Y<AKR/J>
Attribute String: congenic, mutant strain, consomic, targeted mutation
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

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