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Search results 3501 to 3600 out of 3880 for Col2a1

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Type Details Score
Allele
Name: transgene insertion 1, Eleanor C Weir
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
Publication
First Author: Hirai T
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Parathyroid hormone/parathyroid hormone-related protein receptor signaling is required for maintenance of the growth plate in postnatal life.
Volume: 108
Issue: 1
Pages: 191-6
Publication
First Author: Miyazawa T
Year: 2002
Journal: Endocrinology
Title: Cyclic GMP-dependent protein kinase II plays a critical role in C-type natriuretic peptide-mediated endochondral ossification.
Volume: 143
Issue: 9
Pages: 3604-10
Publication
First Author: Posey KL
Year: 2014
Journal: J Bone Miner Res
Title: Chondrocyte-specific pathology during skeletal growth and therapeutics in a murine model of pseudoachondroplasia.
Volume: 29
Issue: 5
Pages: 1258-68
Publication
First Author: Gillespie JR
Year: 2011
Journal: Endocrinology
Title: Deletion of glycogen synthase kinase-3β in cartilage results in up-regulation of glycogen synthase kinase-3α protein expression.
Volume: 152
Issue: 5
Pages: 1755-66
Publication
First Author: Solomon LA
Year: 2013
Journal: PLoS One
Title: Loss of ATRX does not confer susceptibility to osteoarthritis.
Volume: 8
Issue: 12
Pages: e85526
Publication
First Author: Solomon LA
Year: 2009
Journal: PLoS One
Title: Loss of ATRX in chondrocytes has minimal effects on skeletal development.
Volume: 4
Issue: 9
Pages: e7106
Publication  
First Author: Saito M
Year: 2016
Journal: Sci Rep
Title: The Indispensable Role of Cyclin-Dependent Kinase 1 in Skeletal Development.
Volume: 6
Pages: 20622
Publication
First Author: Iezaki T
Year: 2016
Journal: J Pathol
Title: ATF3 deficiency in chondrocytes alleviates osteoarthritis development.
Volume: 239
Issue: 4
Pages: 426-37
Publication  
First Author: Valverde-Franco G
Year: 2016
Journal: Arthritis Res Ther
Title: Cartilage-specific deletion of ephrin-B2 in mice results in early developmental defects and an osteoarthritis-like phenotype during aging in vivo.
Volume: 18
Pages: 65
Publication
First Author: Ikuta K
Year: 2024
Journal: Osteoarthritis Cartilage
Title: Krüppel-like factor 15 deficiency exacerbates osteoarthritis through reduced expression of peroxisome proliferator-activated receptor gamma signaling in mice.
Volume: 32
Issue: 1
Pages: 28-40
Publication
First Author: Ji ML
Year: 2023
Journal: Am J Hum Genet
Title: Dynamic chromatin accessibility tuning by the long noncoding RNA ELDR accelerates chondrocyte senescence and osteoarthritis.
Volume: 110
Issue: 4
Pages: 606-624
Publication
First Author: Ji Q
Year: 2019
Journal: Nat Commun
Title: Hematopoietic PBX-interacting protein mediates cartilage degeneration during the pathogenesis of osteoarthritis.
Volume: 10
Issue: 1
Pages: 313
Allele
Name: transgene insertion 2, Eleanor C Weir
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
Publication
First Author: Zhou G
Year: 2015
Journal: Development
Title: Zbtb20 regulates the terminal differentiation of hypertrophic chondrocytes via repression of Sox9.
Volume: 142
Issue: 2
Pages: 385-93
Allele
Name: transgene insertion 22, Peter J Roughley
Allele Type: Transgenic
Attribute String: Inducible, Recombinase, Transactivator
Allele
Name: transgene insertion, Veronique Lefebvre
Allele Type: Transgenic
Attribute String: Inducible, Recombinase, Transactivator
Strain
Attribute String: transgenic, mutant strain, congenic
Publication
First Author: Tryfonidou MA
Year: 2011
Journal: Dev Dyn
Title: Novel type II collagen reporter mice: New tool for assessing collagen 2α1 expression in vivo and in vitro.
Volume: 240
Issue: 3
Pages: 663-73
Publication
First Author: Bach FC
Year: 2014
Journal: J Cell Physiol
Title: The paracrine feedback loop between vitamin D₃ (1,25(OH)₂D₃) and PTHrP in prehypertrophic chondrocytes.
Volume: 229
Issue: 12
Pages: 1999-2014
Genotype
Symbol: Ilk/Ilk Tg(Col2a1-cre)1Star/?
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Ctnnb1/Ctnnb1 Tg(Col2a1-cre)1Bhr/?
Background: involves: 129S1/Sv * 129X1/SvJ
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Ctnnb1/Ctnnb1<+> Tg(Col2a1-cre)1Bhr/?
Background: involves: 129X1/SvJ
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Bmpr1a/Bmpr1a Tg(Col2a1-cre)1Bhr/?
Background: involves: 129S7/SvEvBrd * C57BL/6 * SJL
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Vdr/Vdr Tg(Col2a1-cre)1Bhr/?
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Runx1/Runx1 Tg(Col2a1-cre)1Star/?
Background: involves: C57BL/6
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Casr/Casr Tg(Col2a1-cre/ERT)KA3Smac/?
Background: involves: 129S4/SvJae * C57BL/6 * FVB/N
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Fgfr3/Fgfr3<+> Tg(Col2a1-cre)1Bhr/?
Background: involves: 129S2/SvPas * C57BL/6 * SJL
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Sox9/Sox9<+> Tg(Col2a1-cre)1Bhr/?
Background: either: (involves: 129S4/SvJae * C57BL/6 * SJL) or (involves: 129S4/SvJae * C57BL/6 * CD-1 * SJL)
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Sox9/Sox9 Tg(Col2a1-cre)1Bhr/?
Background: either: (involves: 129S4/SvJae * C57BL/6 * SJL) or (involves: 129S4/SvJae * C57BL/6 * CD-1 * SJL)
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Ddit3/Ddit3 Tg(Col2a1-rtTA,tetO-COMP*)2Jath/?
Background: involves: 129X1/SvJ * 129S1/Sv * C57BL/6
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Csgalnact1/Csgalnact1 Csgalnact2/Csgalnact2 Tg(Col2a1-cre)1Bhr/?
Background: involves: C57BL/6 * C57BL/6J * SJL
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Tg(COL2A1*R519C)#Afe/Tg(COL2A1*R519C)#Afe
Background: involves: FVB/N
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Tg(COL2A1*R519C)#Afe/?
Background: involves: FVB/N
Zygosity: ot
Has Mutant Allele: true
Genotype
Symbol: Ctnnb1/Ctnnb1<+> Tg(Col2a1-cre)1Bhr/?
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Ctnnb1/Ctnnb1 Tg(Col2a1-cre)1Bhr/?
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Smad2/Smad2 Smad3/Smad3 Tg(Col2a1-cre)1Bhr/?
Background: involves: 129 * C57BL/6J * CD-1 * SJL
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Vegfa/Vegfa<+> Tg(COL2A1-cre)1Wag/?
Background: involves: 129 * C57BL/6 * CBA
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Ilk/Ilk<+> Tg(Col2a1-cre)1Star/?
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Stk11/Stk11 Tg(Col2a1-cre)1Bhr/?
Background: involves: 129S6/SvEvTac * C57BL/6 * FVB * SJL
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Stk11/Stk11<+> Tg(Col2a1-cre)1Bhr/?
Background: involves: 129S6/SvEvTac * C57BL/6 * FVB * SJL
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Tg(Col2a1-cre)1Bhr/? Wls/Wls
Background: involves: 129S6/SvEvTac * C57BL/6 * SJL
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Kdm6a/Kdm6a Tg(Col2a1-cre)1Bhr/?
Background: involves: C57BL/6 * SJL
Zygosity: cn
Has Mutant Allele: true
Publication
First Author: Chen M
Year: 2007
Journal: Genesis
Title: Generation of a transgenic mouse model with chondrocyte-specific and tamoxifen-inducible expression of Cre recombinase.
Volume: 45
Issue: 1
Pages: 44-50
Publication
First Author: Sakai K
Year: 2001
Journal: Matrix Biol
Title: Stage-and tissue-specific expression of a Col2a1-Cre fusion gene in transgenic mice.
Volume: 19
Issue: 8
Pages: 761-7
Publication      
First Author: Korogi W
Year: 2018
Journal: Biochem Biophys Res Commun
Title: SIRT7 is an important regulator of cartilage homeostasis and osteoarthritis development.
Publication
First Author: Lai Y
Year: 2022
Journal: Int J Oral Sci
Title: Kindlin-2 loss in condylar chondrocytes causes spontaneous osteoarthritic lesions in the temporomandibular joint in mice.
Volume: 14
Issue: 1
Pages: 33
Publication
First Author: Pihlajamaa T
Year: 1998
Journal: Matrix Biol
Title: Human COL9A1 and COL9A2 genes. Two genes of 90 and 15 kb code for similar polypeptides of the same collagen molecule.
Volume: 17
Issue: 3
Pages: 237-41
Publication
First Author: Dudek KA
Year: 2010
Journal: J Biol Chem
Title: Type II collagen expression is regulated by tissue-specific miR-675 in human articular chondrocytes.
Volume: 285
Issue: 32
Pages: 24381-7
Publication
First Author: Sono T
Year: 2018
Journal: J Bone Miner Metab
Title: THRAP3 interacts with and inhibits the transcriptional activity of SOX9 during chondrogenesis.
Volume: 36
Issue: 4
Pages: 410-419
Publication
First Author: Tamura N
Year: 2004
Journal: Proc Natl Acad Sci U S A
Title: Critical roles of the guanylyl cyclase B receptor in endochondral ossification and development of female reproductive organs.
Volume: 101
Issue: 49
Pages: 17300-5
Publication
First Author: Parsons TE
Year: 2015
Journal: PLoS One
Title: Mind the gap: genetic manipulation of basicranial growth within synchondroses modulates calvarial and facial shape in mice through epigenetic interactions.
Volume: 10
Issue: 2
Pages: e0118355
Publication
First Author: Arima T
Year: 2024
Journal: J Biol Chem
Title: Cartilage tissues regulate systemic aging via ectonucleotide pyrophosphatase/phosphodiesterase 1 in mice.
Volume: 300
Issue: 1
Pages: 105512
Publication
First Author: Kim BS
Year: 2021
Journal: Sci Rep
Title: Septal chondrocyte hypertrophy contributes to midface deformity in a mouse model of Apert syndrome.
Volume: 11
Issue: 1
Pages: 7979
Publication
First Author: Karlsson C
Year: 2010
Journal: Cells Tissues Organs
Title: HES1 and HES5 are dispensable for cartilage and endochondral bone formation.
Volume: 192
Issue: 1
Pages: 17-27
Publication
First Author: Yu VW
Year: 2016
Journal: Cell
Title: Epigenetic Memory Underlies Cell-Autonomous Heterogeneous Behavior of Hematopoietic Stem Cells.
Volume: 167
Issue: 5
Pages: 1310-1322.e17
Publication  
First Author: Fujiwara Y
Year: 2022
Journal: Front Cell Dev Biol
Title: miR-23a/b clusters are not essential for the pathogenesis of osteoarthritis in mouse aging and post-traumatic models.
Volume: 10
Pages: 1043259
Publication  
First Author: Shtaif B
Year: 2020
Journal: Bone
Title: Cartilage -specific knockout of Sirt1 significantly reduces bone quality and catch-up growth efficiency.
Volume: 138
Pages: 115468
Publication
First Author: Kinumatsu T
Year: 2011
Journal: J Dent Res
Title: TMJ development and growth require primary cilia function.
Volume: 90
Issue: 8
Pages: 988-94
Publication
First Author: Bradley EW
Year: 2015
Journal: J Biol Chem
Title: Histone deacetylase 7 (Hdac7) suppresses chondrocyte proliferation and β-catenin activity during endochondral ossification.
Volume: 290
Issue: 1
Pages: 118-26
Publication  
First Author: Matsuzaki T
Year: 2018
Journal: Sci Transl Med
Title: FoxO transcription factors modulate autophagy and proteoglycan 4 in cartilage homeostasis and osteoarthritis.
Volume: 10
Issue: 428
Publication
First Author: Mi M
Year: 2013
Journal: Gene
Title: Chondrocyte BMP2 signaling plays an essential role in bone fracture healing.
Volume: 512
Issue: 2
Pages: 211-8
Publication  
First Author: Heilig J
Year: 2016
Journal: Bone
Title: Insulin-like growth factor 1 receptor (IGF1R) signaling regulates osterix expression and cartilage matrix mineralization during endochondral ossification.
Volume: 83
Pages: 48-57
Publication  
First Author: Lui JC
Year: 2016
Journal: Nat Commun
Title: EZH1 and EZH2 promote skeletal growth by repressing inhibitors of chondrocyte proliferation and hypertrophy.
Volume: 7
Pages: 13685
Publication  
First Author: Shtaif B
Year: 2021
Journal: Front Endocrinol (Lausanne)
Title: Anxiety and Cognition in Cre- Collagen Type II Sirt1 K/O Male Mice.
Volume: 12
Pages: 756909
Publication  
First Author: Eelen G
Year: 2016
Journal: J Steroid Biochem Mol Biol
Title: Forkhead box O transcription factors in chondrocytes regulate endochondral bone formation.
Volume: 164
Pages: 337-343
Publication
First Author: Jacob AL
Year: 2006
Journal: Dev Biol
Title: Fibroblast growth factor receptor 1 signaling in the osteo-chondrogenic cell lineage regulates sequential steps of osteoblast maturation.
Volume: 296
Issue: 2
Pages: 315-28
Publication
First Author: Song B
Year: 2007
Journal: Dev Biol
Title: Development of the post-natal growth plate requires intraflagellar transport proteins.
Volume: 305
Issue: 1
Pages: 202-16
Publication
First Author: Tschaffon-Müller MEA
Year: 2023
Journal: Nat Commun
Title: Neutrophil-derived catecholamines mediate negative stress effects on bone.
Volume: 14
Issue: 1
Pages: 3262
Publication
First Author: Piróg KA
Year: 2019
Journal: PLoS Genet
Title: XBP1 signalling is essential for alleviating mutant protein aggregation in ER-stress related skeletal disease.
Volume: 15
Issue: 7
Pages: e1008215
Publication
First Author: Cameron TL
Year: 2015
Journal: PLoS Genet
Title: XBP1-Independent UPR Pathways Suppress C/EBP-β Mediated Chondrocyte Differentiation in ER-Stress Related Skeletal Disease.
Volume: 11
Issue: 9
Pages: e1005505
Publication
First Author: Xu T
Year: 2018
Journal: J Cell Biochem
Title: Ablation of Dnmt3b in chondrocytes suppresses cell maturation during embryonic development.
Volume: 119
Issue: 7
Pages: 5852-5863
Publication  
First Author: Mirzamohammadi F
Year: 2016
Journal: Nat Commun
Title: Polycomb repressive complex 2 regulates skeletal growth by suppressing Wnt and TGF-β signalling.
Volume: 7
Pages: 12047
Publication
First Author: Vasheghani F
Year: 2013
Journal: Am J Pathol
Title: Adult cartilage-specific peroxisome proliferator-activated receptor gamma knockout mice exhibit the spontaneous osteoarthritis phenotype.
Volume: 182
Issue: 4
Pages: 1099-106
Publication  
First Author: Yang C
Year: 2017
Journal: Biomed Res Int
Title: Chondrocyte-Specific Knockout of TSC-1 Leads to Congenital Spinal Deformity in Mice.
Volume: 2017
Pages: 8215805
Publication
First Author: Sgariglia F
Year: 2013
Journal: Bone
Title: Epiphyseal abnormalities, trabecular bone loss and articular chondrocyte hypertrophy develop in the long bones of postnatal Ext1-deficient mice.
Volume: 57
Issue: 1
Pages: 220-31
Publication
First Author: Li S
Year: 2018
Journal: Sci Rep
Title: Knockdown Indian Hedgehog (Ihh) does not delay Fibular Fracture Healing in genetic deleted Ihh mice and pharmaceutical inhibited Ihh Mice.
Volume: 8
Issue: 1
Pages: 10351
Publication
First Author: Chavez RD
Year: 2019
Journal: PLoS One
Title: Prg4 prevents osteoarthritis induced by dominant-negative interference of TGF-ß signaling in mice.
Volume: 14
Issue: 1
Pages: e0210601
Publication
First Author: Chou LY
Year: 2020
Journal: FASEB J
Title: Discoidin domain receptor 1 regulates endochondral ossification through terminal differentiation of chondrocytes.
Volume: 34
Issue: 4
Pages: 5767-5781
Publication
First Author: Ji ML
Year: 2022
Journal: Nat Commun
Title: Sirt6 attenuates chondrocyte senescence and osteoarthritis progression.
Volume: 13
Issue: 1
Pages: 7658
Publication
First Author: Zhen G
Year: 2021
Journal: Nat Commun
Title: Mechanical stress determines the configuration of TGFβ activation in articular cartilage.
Volume: 12
Issue: 1
Pages: 1706
Strain
Attribute String: transgenic, mutant stock
Genotype
Symbol: Jun/Jun Tg(COL2A1-cre)1Wag/?
Background: involves: 129P2/OlaHsd * C57BL/6 * CBA
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Tg(Col2a1-PTHLH)1Ecw/?
Background: involves: C57BL/6 * SJL
Zygosity: ot
Has Mutant Allele: true
Genotype
Symbol: Ctnnb1/Ctnnb1 Tg(Col2a1-cre)1Bhr/?
Background: involves: 129S6/SvEvTac * C57BL/6 * SJL
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Kif3a/Kif3a Tg(Col2a1-cre)1Bhr/?
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Tg(Col2a1-PTHLH)2Ecw/?
Background: involves: C57BL/6 * SJL
Zygosity: ot
Has Mutant Allele: true
Genotype
Symbol: Hdac8/? Tg(Col2a1-cre)1Bhr/?
Background: involves: 129 * C57BL/6 * CD-1 * SJL
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Kdr/Kdr Tg(Col2a1-cre)1Bhr/?
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * ICR * SJL
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Ext1/Ext1<+> Tg(Col2a1-cre)1Bhr/?
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Runx1/Runx1 Runx2/Runx2 Tg(Col2a1-cre)1Star/?
Background: involves: C57BL/6
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Ext1/Ext1 Tg(Col2a1-cre/ERT)KA3Smac/?
Background: involves: 129S5/SvEvBrd * FVB/N
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Tg(CAG-mRFP1,-SOX9,-EGFP)1Haak/? Tg(Col2a1-cre)1Bhr/?
Background: involves: C57BL/6 * SJL
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Runx2/Runx2 Tg(Col2a1-cre)1Star/?
Background: involves: C57BL/6 * C57BL/6NCrlj * CBA/JNCrlj
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Dot1l/Dot1l Tg(Col2a1-cre)1Bhr/?
Background: involves: 129S4/SvJaeSor * C57BL/6 * C57BL/6N * SJL
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Tsc1/Tsc1 Tg(Col2a1-cre/ERT)KA3Smac/?
Background: involves: 129S4/SvJae * FVB/N
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Gli2/Gli2 Ihh/Ihh Tg(COL2A1-cre)1Wag/?
Background: involves: 129 * C57BL/6J * CBA
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Dnmt3b/Dnmt3b Tg(Col2a1-cre)1Bhr/?
Background: involves: 129S4/SvJae * C57BL/6 * SJL
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Tg(CAG-cat,-lacZ)1Brn/? Tg(COL2A1-cre)1Wag/?
Background: involves: C57BL/6 * CBA * FVB/N
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Col2a1-cre)1Xya/?
Background: involves: 129S4/SvJaeSor
Zygosity: cn
Has Mutant Allele: true