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Search results 3501 to 3600 out of 6327 for Kit

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Type Details Score
Publication  
First Author: Beechey CV
Year: 1985
Journal: Mouse News Lett
Title: Male-fertile black-eyed white at Sl locus
Volume: 73
Pages: 17
Publication
First Author: Liao CP
Year: 2017
Journal: Genes Dev
Title: Identification of hair shaft progenitors that create a niche for hair pigmentation.
Volume: 31
Issue: 8
Pages: 744-756
Publication
First Author: Dahlin JS
Year: 2018
Journal: Blood
Title: A single-cell hematopoietic landscape resolves 8 lineage trajectories and defects in Kit mutant mice.
Volume: 131
Issue: 21
Pages: e1-e11
Publication  
First Author: Green MC
Year: 1973
Journal: Mouse News Lett
Title: Locus order Hd - Mi - me.
Volume: 49
Pages: 32
Publication
First Author: Kanatsu-Shinohara M
Year: 2024
Journal: PNAS Nexus
Title: Sendai virus-mediated RNA delivery restores fertility to congenital and chemotherapy-induced infertile female mice.
Volume: 3
Issue: 9
Pages: pgae375
HT Sample
Organism Name: mouse, laboratory
Sex: Not Specified
Age: postnatal month 2-9
Stage: 28
Structure . Name: serum
Notes: TruSeq small RNA library preparation kit v2 (Illumina)
Curation Status: Curated
HT Sample
Organism Name: mouse, laboratory
Sex: Not Specified
Age: postnatal month 2-9
Stage: 28
Structure . Name: serum
Notes: TruSeq small RNA library preparation kit v2 (Illumina)
Curation Status: Curated
Publication
First Author: Gallardo TD
Year: 2007
Journal: Genetics
Title: Genomewide discovery and classification of candidate ovarian fertility genes in the mouse.
Volume: 177
Issue: 1
Pages: 179-94
HT Experiment
Series Id: GSE12905
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
HT Experiment  
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
Interaction Experiment
Description: Interkinase domain of kit contains the binding site for phosphatidylinositol 3 kinase.
Strain
Attribute String: mutant strain, spontaneous mutation, coisogenic
Strain
Attribute String: mutant strain, spontaneous mutation
Strain
Attribute String: mutant strain, coisogenic, spontaneous mutation
Strain
Attribute String: congenic, mutant strain
Genotype
Symbol: Kit/Kit
Background: involves: C3H/HeJ
Zygosity: hm
Has Mutant Allele: true
Publication
First Author: Rae J
Year: 2012
Journal: J Invest Dermatol
Title: (V600E)Braf::Tyr-CreERT2::K14-Kitl mice do not develop superficial spreading-like melanoma: keratinocyte Kit ligand is insufficient to "translocate" (V600E)Braf-driven melanoma to the epidermis.
Volume: 132
Issue: 2
Pages: 488-91
GXD Expression
Probe: MGI:7641521
Assay Type: Immunohistochemistry
Annotation Date: 2024-05-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1633219
Pattern: Single cells
Stage: TS19
Assay Id: MGI:7641780
Age: embryonic day 11.5
Image: 3G/H
Note: Weakly coexpressed with Kit in some of the single cells.
Specimen Label: 3G/H
Detected: true
Specimen Num: 2
GXD Expression
Probe: MGI:1332776
Assay Type: Immunohistochemistry
Annotation Date: 1999-03-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1617717
Pattern: Spotted
Stage: TS17
Assay Id: MGI:1332789
Age: embryonic day 10.5
Image: 6.A.
Note: Both Kit single-positive and Kit/Mitf double-positive cells are detected.
Specimen Label: 6.A.
Detected: true
Specimen Num: 1
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2024-08-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3820119
Pattern: Regionally restricted
Stage: TS19
Assay Id: MGI:7707694
Age: embryonic day 11.5
Note: Co-expression with Kit n mesenchymal cells directly under the endothelium.
Specimen Label: 4B
Detected: true
Specimen Num: 6
Allele
Name: KIT proto-oncogene receptor tyrosine kinase; targeted mutation 1, Chen-Leng Cai
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
Allele
Name: KIT proto-oncogene receptor tyrosine kinase; targeted mutation 2, Chen-Leng Cai
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
Publication
First Author: Chaix A
Year: 2011
Journal: J Biol Chem
Title: Mechanisms of STAT protein activation by oncogenic KIT mutants in neoplastic mast cells.
Volume: 286
Issue: 8
Pages: 5956-66
Genotype
Symbol: Kitl/Kitl
Background: B6;129S1-a Kitl/GrsrJ
Zygosity: hm
Has Mutant Allele: true
Publication
First Author: Simonowski A
Year: 2020
Journal: Biochim Biophys Acta Mol Cell Res
Title: Differential use of BTK and PLC in FcεRI- and KIT-mediated mast cell activation: A marginal role of BTK upon KIT activation.
Volume: 1867
Issue: 4
Pages: 118622
Publication
First Author: Johansson Moller M
Year: 1996
Journal: Mamm Genome
Title: Pigs with the dominant white coat color phenotype carry a duplication of the KIT gene encoding the mast/stem cell growth factor receptor.
Volume: 7
Issue: 11
Pages: 822-30
Publication
First Author: Sundberg JP
Year: 1992
Journal: J Vet Diagn Invest
Title: Forestomach papillomas in flaky skin and steel-Dickie mutant mice.
Volume: 4
Issue: 3
Pages: 312-7
Publication
First Author: Ohta H
Year: 2003
Journal: Biol Reprod
Title: Functional analysis of the p53 gene in apoptosis induced by heat stress or loss of stem cell factor signaling in mouse male germ cells.
Volume: 68
Issue: 6
Pages: 2249-54
Gene
Type: gene
Organism: human
Publication
First Author: Rai S
Year: 2014
Journal: PLoS One
Title: Clathrin assembly protein CALM plays a critical role in KIT signaling by regulating its cellular transport from early to late endosomes in hematopoietic cells.
Volume: 9
Issue: 10
Pages: e109441
Publication
First Author: Stevens LC
Year: 1973
Journal: J Natl Cancer Inst
Title: A new inbred subline of mice (129-terSv) with a high incidence of spontaneous congenital testicular teratomas.
Volume: 50
Issue: 1
Pages: 235-42
Allele  
Name: KIT proto-oncogene receptor tyrosine kinase; dominant spotting RIKEN BioResource Center
Allele Type: Spontaneous
Publication
First Author: Chen R
Year: 2002
Journal: J Immunol
Title: Macrophages, but not T and B lymphocytes, are critical for subepidermal blister formation in experimental bullous pemphigoid: macrophage-mediated neutrophil infiltration depends on mast cell activation.
Volume: 169
Issue: 7
Pages: 3987-92
Allele  
Name: kit ligand; sooty
Allele Type: Radiation induced
Allele  
Name: kit ligand; blaze
Allele Type: Spontaneous
Allele  
Name: KIT proto-oncogene receptor tyrosine kinase; banded
Allele Type: Spontaneous
Allele  
Name: KIT proto-oncogene receptor tyrosine kinase; sash
Allele Type: Spontaneous
Publication
First Author: Lyman SD
Year: 1992
Journal: Am J Pediatr Hematol Oncol
Title: Biological activities and potential therapeutic uses of steel factor. A new growth factor active on multiple hematopoietic lineages.
Volume: 14
Issue: 1
Pages: 1-7
Publication
First Author: Ryan JJ
Year: 1997
Journal: Exp Hematol
Title: Stem cell factor activates STAT-5 DNA binding in IL-3-derived bone marrow mast cells.
Volume: 25
Issue: 4
Pages: 357-62
Genotype
Symbol: Kit/Kit<+>
Background: involves: C3H/HeJ
Zygosity: ht
Has Mutant Allele: true
GO Term
GO Term
Publication
First Author: Aylor DL
Year: 2011
Journal: Genome Res
Title: Genetic analysis of complex traits in the emerging Collaborative Cross.
Volume: 21
Issue: 8
Pages: 1213-22
Publication
First Author: Kapur R
Year: 2002
Journal: Blood
Title: Role of p38 and ERK MAP kinase in proliferation of erythroid progenitors in response to stimulation by soluble and membrane isoforms of stem cell factor.
Volume: 100
Issue: 4
Pages: 1287-93
Publication  
First Author: Russell LB
Year: 1953
Journal: Mouse News Lett
Title: Steel (Sl) and Pearl (pe)
Volume: 8
Pages: 14
HT Experiment
Series Id: E-GEOD-62741
Experiment Type: RNA-Seq
Study Type: Baseline
Source: GEO
Interaction Experiment
Description: Dimerization and activation of the kit receptor by monovalent and bivalent binding of the stem cell factor.
Publication
First Author: Gopalan G
Year: 1999
Journal: Mol Reprod Dev
Title: Novel mammalian kinase related to yeast and fly chromosome segregation regulators is exclusively expressed in the germline.
Volume: 52
Issue: 1
Pages: 18-28
Allele  
Name: KIT proto-oncogene receptor tyrosine kinase; dominant spotting 42 Jackson
Allele Type: Spontaneous
Allele
Name: KIT proto-oncogene receptor tyrosine kinase; targeted mutation 1.1, Chen-Leng Cai
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
Allele
Name: KIT proto-oncogene receptor tyrosine kinase; targeted mutation 2.1, Chen-Leng Cai
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
Allele
Name: KIT proto-oncogene receptor tyrosine kinase; endonuclease-mediated mutation 2, Bin Zhou
Allele Type: Endonuclease-mediated
Attribute String: Recombinase
Allele
Name: KIT proto-oncogene receptor tyrosine kinase; endonuclease-mediated mutation 1, Bin Zhou
Allele Type: Endonuclease-mediated
Attribute String: Recombinase
Strain
Attribute String: mutant strain, spontaneous mutation
Strain
Attribute String: congenic, mutant strain, spontaneous mutation
Strain
Attribute String: mutant stock, spontaneous mutation
Strain
Attribute String: mutant strain
Strain
Attribute String: mutant strain
Strain
Attribute String: F1 hybrid, mutant stock
Genotype
Symbol: Kitl/Kitl
Background: involves: C3H
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Kitl/Kitl
Background: WB.C3-Kitl
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Kitl/Kitl
Background: Not Specified
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Kitl/Kitl
Background: involves: 129 * 129S6/SvEvTac * C3H * C57BL/6
Zygosity: hm
Has Mutant Allele: true
Publication  
First Author: Miller DS
Year: 1963
Journal: Radiat Res
Title: Coat color and behavior mutations in inbred mice under chronic low-level gamma-irradiation.
Volume: 19
Pages: 184-185
Publication
First Author: Lam MY
Year: 2004
Journal: Genetics
Title: Enhancers and suppressors of testicular cancer susceptibility in single- and double-mutant mice.
Volume: 166
Issue: 2
Pages: 925-33
Publication
First Author: de Rooij DG
Year: 1999
Journal: Biol Reprod
Title: Arrest of spermatogonial differentiation in jsd/jsd, Sl17H/Sl17H, and cryptorchid mice.
Volume: 61
Issue: 3
Pages: 842-7
Allele  
Name: KIT proto-oncogene receptor tyrosine kinase; dominant spotting 2 RIKEN BioResource Center
Allele Type: Spontaneous
Allele
Name: KIT proto-oncogene receptor tyrosine kinase; targeted mutation 1, Shanghai Model Organisms Center
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
HT Sample
Organism Name: mouse, laboratory
Sex: Not Specified
Age: embryonic day 9.5
Stage: 15
Structure . Name: yolk sac
Notes: Hemogenic endothelial cells isolated from yolk sac (Runx1-GFP+, CD31+, kit lo/-, CD41-, CD45-)
Curation Status: Curated
HT Sample
Organism Name: mouse, laboratory
Sex: Not Specified
Age: embryonic day 9.5
Stage: 15
Structure . Name: yolk sac
Notes: Hemogenic endothelial cells isolated from yolk sac (Runx1-GFP+, CD31+, kit lo/-, CD41-, CD45-)
Curation Status: Curated
HT Sample
Organism Name: mouse, laboratory
Sex: Not Specified
Age: embryonic day 10.5
Stage: 17
Structure . Name: yolk sac
Notes: Hemogenic endothelial cells isolated from yolk sac (Runx1-GFP+, CD31+, kit lo/-, CD41-, CD45-)
Curation Status: Curated
HT Sample
Organism Name: mouse, laboratory
Sex: Not Specified
Age: embryonic day 10.5
Stage: 17
Structure . Name: yolk sac
Notes: Hemogenic endothelial cells isolated from yolk sac (Runx1-GFP+, CD31+, kit lo/-, CD41-, CD45-)
Curation Status: Curated
Allele  
Name: KIT proto-oncogene receptor tyrosine kinase; targeted mutation 1, Peter Besmer
Allele Type: Targeted
Allele  
Name: KIT proto-oncogene receptor tyrosine kinase; targeted mutation 1.1, Peter Besmer
Allele Type: Targeted
Allele
Name: KIT proto-oncogene receptor tyrosine kinase; targeted mutation 1, Dieter Saur
Allele Type: Targeted
Attribute String: Inducible, Recombinase
Allele
Name: KIT proto-oncogene receptor tyrosine kinase; targeted mutation 1.2, Chen-Leng Cai
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
Allele
Name: KIT proto-oncogene receptor tyrosine kinase; targeted mutation 2, Chen-Leng Cai
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
Allele
Name: KIT proto-oncogene receptor tyrosine kinase; targeted mutation 3, Chen-Leng Cai
Allele Type: Targeted
Attribute String: Inducible, Null/knockout, Recombinase
Allele
Name: KIT proto-oncogene receptor tyrosine kinase; targeted mutation 3.1, Chen-Leng Cai
Allele Type: Targeted
Attribute String: Inducible, Null/knockout, Recombinase
Allele
Name: KIT proto-oncogene receptor tyrosine kinase; targeted mutation 1, Klaus Karjalainen
Allele Type: Targeted
Attribute String: Inducible, Recombinase
Allele
Name: KIT proto-oncogene receptor tyrosine kinase; endonuclease-mediated mutation 1, Cyagen Biosciences
Allele Type: Endonuclease-mediated
Attribute String: Not Specified
HT Experiment  
Experiment Type: RNA-Seq
Study Type: Baseline
Source: GEO
Publication
First Author: Liao CP
Year: 2018
Journal: J Clin Invest
Title: Contributions of inflammation and tumor microenvironment to neurofibroma tumorigenesis.
Volume: 128
Issue: 7
Pages: 2848-2861
Publication
First Author: Comazzetto S
Year: 2019
Journal: Cell Stem Cell
Title: Restricted Hematopoietic Progenitors and Erythropoiesis Require SCF from Leptin Receptor+ Niche Cells in the Bone Marrow.
Volume: 24
Issue: 3
Pages: 477-486.e6
Genotype
Symbol: Kit/Kit<+> Ph/Ph<+>
Background: involves: C57BL
Zygosity: cx
Has Mutant Allele: true
GO Term
GO Term
GXD Expression
Probe: MGI:3850031
Assay Type: Immunohistochemistry
Annotation Date: 2015-07-31
Strength: Present
Sex: Male
Emaps: EMAPS:3148228
Pattern: Clusters
Stage: TS28
Assay Id: MGI:5645701
Age: postnatal adult
Image: S4C
Note: Expressed in differentiating spermatogonia. Co-expressed with Kit in Aal and a portion of the differentiating spermatogonia.
Specimen Label: S4C
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:3850031
Assay Type: Immunohistochemistry
Annotation Date: 2015-07-31
Strength: Present
Sex: Male
Emaps: EMAPS:3148228
Pattern: Clusters
Stage: TS28
Assay Id: MGI:5645701
Age: postnatal adult
Image: S4D
Note: Expressed in differentiating spermatogonia. Co-expressed with Kit in Aal and a portion of the differentiating spermatogonia.
Specimen Label: S4D
Detected: true
Specimen Num: 2
GXD Expression
Probe: MGI:3850031
Assay Type: Immunohistochemistry
Annotation Date: 2015-07-31
Strength: Present
Sex: Male
Emaps: EMAPS:3148228
Pattern: Clusters
Stage: TS28
Assay Id: MGI:5645701
Age: postnatal adult
Image: S4E
Note: But did not co-expressed with Kit (B-type spermatogonia and preleptotene spermatocytes) from stages V to VIII.
Specimen Label: S4E
Detected: true
Specimen Num: 3
GXD Expression
Probe: MGI:6391407
Assay Type: Immunohistochemistry
Annotation Date: 2020-07-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1620417
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:6443688
Age: embryonic day 10.5
Image: 10A SOX7 (upper)
Note: Co-expression with Runx and Kit in emerging blood cells on ventral aspect of dorsal aorta.
Specimen Label: 10A SOX7 (upper)
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:6391407
Assay Type: Immunohistochemistry
Annotation Date: 2020-07-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1620417
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:6443688
Age: embryonic day 10.5
Image: 10A SOX7 (lower)
Note: Co-expression with Runx and Kit in emerging blood cells on ventral aspect of dorsal aorta.
Specimen Label: 10A SOX7 (lower)
Detected: true
Specimen Num: 2
GXD Expression
Probe: MGI:3702648
Assay Type: Immunohistochemistry
Annotation Date: 2023-01-25
Strength: Present
Sex: Male
Emaps: EMAPS:1797523
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:7428653
Age: embryonic day 15.5
Image: 5A
Note: Expressed in some of the germ cells. Co-expressed with Kit was occasionally observed.
Specimen Label: 5A
Detected: true
Specimen Num: 4
GXD Expression
Probe: MGI:3702648
Assay Type: Immunohistochemistry
Annotation Date: 2023-01-25
Strength: Present
Sex: Male
Emaps: EMAPS:1797523
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:7428653
Age: embryonic day 15.5
Image: 5B
Note: Expressed in some of the germ cells. Co-expressed with Kit was occasionally observed.
Specimen Label: 5B
Detected: true
Specimen Num: 5
GXD Expression
Probe: MGI:3702648
Assay Type: Immunohistochemistry
Annotation Date: 2023-01-25
Strength: Present
Sex: Male
Emaps: EMAPS:1797523
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:7428653
Age: embryonic day 15.5
Image: 5C
Note: Expressed in some of the germ cells. Co-expressed with Kit was occasionally observed.
Specimen Label: 5C
Detected: true
Specimen Num: 6
GXD Expression
Probe: MGI:6297085
Assay Type: Immunohistochemistry
Annotation Date: 2019-05-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3102527
Pattern: Regionally restricted
Stage: TS27
Assay Id: MGI:6297089
Age: postnatal day 1
Image: 3A/C
Note: Authors report expressionin some oocytes co-expressing Kit and some oocytes not expressing Kit.
Specimen Label: 3A/C
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:6297085
Assay Type: Immunohistochemistry
Annotation Date: 2019-05-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3102527
Pattern: Regionally restricted
Stage: TS27
Assay Id: MGI:6297089
Age: postnatal day 1
Image: 3D/F
Note: Authors report expressionin some oocytes co-expressing Kit and some oocytes not expressing Kit.
Specimen Label: 3D/F
Detected: true
Specimen Num: 2
Publication      
First Author: Medical Research Council (MRC) Harwell
Year: 2012
Journal: MGI Direct Data Submission
Title: Direct Data Submission 2012/01/18
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli