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Search results 3601 to 3700 out of 4449 for Apc

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Type Details Score
Publication
27876794 | J:243072
 
First Author: Miyamoto Y
Year: 2016
Journal: Nat Commun
Title: VCAM1 acts in parallel with CD69 and is required for the initiation of oligodendrocyte myelination.
Volume: 7
Pages: 13478
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Publication
22627280 | J:185534
First Author: Zhu X
Year: 2012
Journal: Development
Title: Olig2-dependent developmental fate switch of NG2 cells.
Volume: 139
Issue: 13
Pages: 2299-307
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Publication
24569435 | J:210265
 
First Author: Su Z
Year: 2014
Journal: Nat Commun
Title: In vivo conversion of astrocytes to neurons in the injured adult spinal cord.
Volume: 5
Pages: 3338
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Publication
28719590 | J:249696
 
First Author: Teichert M
Year: 2017
Journal: Nat Commun
Title: Pericyte-expressed Tie2 controls angiogenesis and vessel maturation.
Volume: 8
Pages: 16106
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Publication
37657440 | J:342974
First Author: Rojo D
Year: 2023
Journal: Neuron
Title: BMAL1 loss in oligodendroglia contributes to abnormal myelination and sleep.
Volume: 111
Issue: 22
Pages: 3604-3618.e11
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Publication
29694884 | J:270855
First Author: Arango-Lievano M
Year: 2018
Journal: Cell Rep
Title: Topographic Reorganization of Cerebrovascular Mural Cells under Seizure Conditions.
Volume: 23
Issue: 4
Pages: 1045-1059
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Publication
31015293 | J:275798
First Author: Ferrari Bardile C
Year: 2019
Journal: Proc Natl Acad Sci U S A
Title: Intrinsic mutant HTT-mediated defects in oligodendroglia cause myelination deficits and behavioral abnormalities in Huntington disease.
Volume: 116
Issue: 19
Pages: 9622-9627
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Genotype
Genotype
Symbol: Ifi208/Ifi208<+> Tubb4a/Tubb4a
Background: involves: C57BL/6 * C57BL/6N * FVB/N * SJL
Zygosity: cn
Has Mutant Allele: true
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Publication
10700176 | -
First Author: Satoh S
Year: 2000
Journal: Nat Genet
Title: AXIN1 mutations in hepatocellular carcinomas, and growth suppression in cancer cells by virus-mediated transfer of AXIN1.
Volume: 24
Issue: 3
Pages: 245-50
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Protein Domain
IPR015669 | Endothetial_C_recpt
Type: Family
Description: Upon vascular injury, flowing blood is exposed to cells expressing tissue factor (TF) on their surfaces and FVII/FVIIa binds to its receptor/cofactor TF and is rapidly activated to FVIIa and the activity of bound FVIIa is dramatically enhanced. The TF/FVIIa complex activates zymogens factor X (FX) and factor IX (FIX). The FXa, in the absence of activated cofactor factor Va (FVa) generates only trace amounts of thrombin. Although insufficient to initiate fibrin polymerisation alone, these small amounts of thrombin, however, back activate factors V (FV), VIII (FVIII), and XI(FXI). FVIII and FV function as membrane-bound cofactors for proteinases FIXa and FXa, respectively increasing the Vmax of the reaction complexes dramatically. Amplification of the pro-coagulant response consequently occurs through formation of the tenase complex FIXa/FVIIIa and the thrombinase complex FXa/FVa that generate sufficient amounts of thrombin to mediate sustained haemostasis.In addition to its function in cleaving soluble fibrinogen to form insoluble fibrin monomers, thrombin can also activate an anticoagulant pathway. Thrombomodulin (TM), a receptor present on the endothelial cell surface, binds thrombin and alters thrombin's substrate specificity through an allosteric mechanism. Bound to TM, thrombin can no longer efficiently proteolyse its pro-coagulant substrates FV, FVIII and fibrinogen. The thrombin-TM complex proteolytically activates its substrate protein C (PC) to activated protein C (APC). In complex with its cofactor protein S (PS), APC rapidly inactivates pro-coagulant factors FVa and FVIIIa by further proteolysis in a negative feedback loop. Activation of protein C by thrombin bound to thrombomodulin is enhanced by endothelial protein C receptor (EPCR). The EPCR is an N-glycosylated type I membrane protein and mutations in this EPCR gene have been associated with venous thromboembolism and myocardial infarction, as well as with late foetal loss during pregnancy.
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Publication
11348595 | J:182415
First Author: Huber AH
Year: 2001
Journal: Cell
Title: The structure of the beta-catenin/E-cadherin complex and the molecular basis of diverse ligand recognition by beta-catenin.
Volume: 105
Issue: 3
Pages: 391-402
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Publication
16809773 | J:110317
First Author: Lee H
Year: 2006
Journal: Mol Cell Biol
Title: Mouse emi1 has an essential function in mitotic progression during early embryogenesis.
Volume: 26
Issue: 14
Pages: 5373-81
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Publication
19362712 | J:149492
First Author: Drage MG
Year: 2009
Journal: Cell Immunol
Title: TLR2 and its co-receptors determine responses of macrophages and dendritic cells to lipoproteins of Mycobacterium tuberculosis.
Volume: 258
Issue: 1
Pages: 29-37
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Publication
30361697 | J:269986
First Author: Jung YS
Year: 2018
Journal: Nat Cell Biol
Title: Deregulation of CRAD-controlled cytoskeleton initiates mucinous colorectal cancer via β-catenin.
Volume: 20
Issue: 11
Pages: 1303-1314
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Publication
15542852 | J:94306
First Author: Akhter S
Year: 2004
Journal: Mol Cell Biol
Title: Deficiency in SNM1 abolishes an early mitotic checkpoint induced by spindle stress.
Volume: 24
Issue: 23
Pages: 10448-55
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Publication
12818166 | J:85122
First Author: Prasad DV
Year: 2003
Journal: Immunity
Title: B7S1, a novel B7 family member that negatively regulates T cell activation.
Volume: 18
Issue: 6
Pages: 863-73
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Publication
9697701 | J:48968
First Author: Korinek V
Year: 1998
Journal: Nat Genet
Title: Depletion of epithelial stem-cell compartments in the small intestine of mice lacking Tcf-4.
Volume: 19
Issue: 4
Pages: 379-83
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Publication
10656974 | J:60281
First Author: Seidensticker MJ
Year: 2000
Journal: Biochim Biophys Acta
Title: Biochemical interactions in the wnt pathway.
Volume: 1495
Issue: 2
Pages: 168-82
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Publication
32615086 | J:304738
First Author: Oguri Y
Year: 2020
Journal: Cell
Title: CD81 Controls Beige Fat Progenitor Cell Growth and Energy Balance via FAK Signaling.
Volume: 182
Issue: 3
Pages: 563-577.e20
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Publication
15366372 | J:92308
First Author: Lee D
Year: 2004
Journal: Mamm Genome
Title: Wa5 is a novel ENU-induced antimorphic allele of the epidermal growth factor receptor.
Volume: 15
Issue: 7
Pages: 525-36
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Publication
28954823 | J:249191
First Author: Capece T
Year: 2017
Journal: J Cell Biol
Title: A novel intracellular pool of LFA-1 is critical for asymmetric CD8+ T cell activation and differentiation.
Volume: 216
Issue: 11
Pages: 3817-3829
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Publication
31019259 | J:298414
First Author: Wirasinha RC
Year: 2019
Journal: Cell Death Differ
Title: Deletion of self-reactive CCR7- thymocytes in the absence of MHC expression on thymic epithelial cells.
Volume: 26
Issue: 12
Pages: 2727-2739
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Publication
19596982 | J:151587
First Author: Niu N
Year: 2009
Journal: J Immunol
Title: Cutting edge: Limiting MHC class II expression to dendritic cells alters the ability to develop Th2- dependent allergic airway inflammation.
Volume: 183
Issue: 3
Pages: 1523-7
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Publication
32294445 | J:300915
First Author: Cham LB
Year: 2020
Journal: Cell Rep
Title: Immunotherapeutic Blockade of CD47 Inhibitory Signaling Enhances Innate and Adaptive Immune Responses to Viral Infection.
Volume: 31
Issue: 2
Pages: 107494
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Publication
17114442 | J:140848
First Author: Noorchashm H
Year: 2006
Journal: J Immunol
Title: B cell-mediated antigen presentation is required for the pathogenesis of acute cardiac allograft rejection.
Volume: 177
Issue: 11
Pages: 7715-22
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Publication
30271984 | J:278050
 
First Author: Shahzad K
Year: 2018
Journal: Commun Biol
Title: Activated protein C reverses epigenetically sustained p66Shc expression in plaque-associated macrophages in diabetes.
Volume: 1
Pages: 104
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Publication
20127674 | J:159191
First Author: Gruber A
Year: 2010
Journal: Eur J Immunol
Title: Parenchymal cells critically curtail cytotoxic T-cell responses by inducing Bim-mediated apoptosis.
Volume: 40
Issue: 4
Pages: 966-75
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Publication
9725199 | J:118387
First Author: Mackey MF
Year: 1998
Journal: J Immunol
Title: Dendritic cells require maturation via CD40 to generate protective antitumor immunity.
Volume: 161
Issue: 5
Pages: 2094-8
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Publication
27827367 | J:242721
 
First Author: Shin H
Year: 2016
Journal: Nat Commun
Title: CD301b+ dendritic cells stimulate tissue-resident memory CD8+ T cells to protect against genital HSV-2.
Volume: 7
Pages: 13346
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Publication
32392463 | J:290467
First Author: Bosteels C
Year: 2020
Journal: Immunity
Title: Inflammatory Type 2 cDCs Acquire Features of cDC1s and Macrophages to Orchestrate Immunity to Respiratory Virus Infection.
Volume: 52
Issue: 6
Pages: 1039-1056.e9
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Publication
20494341 | J:162109
First Author: Blink SE
Year: 2010
Journal: Cell Immunol
Title: IgE regulates T helper cell differentiation through FcgammaRIII mediated dendritic cell cytokine modulation.
Volume: 264
Issue: 1
Pages: 54-60
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Publication
16547257 | J:129875
First Author: Martín-Cófreces NB
Year: 2006
Journal: J Immunol
Title: Role of Fyn in the rearrangement of tubulin cytoskeleton induced through TCR.
Volume: 176
Issue: 7
Pages: 4201-7
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Publication
10553048 | J:118448
First Author: Malkiel S
Year: 1999
Journal: J Immunol
Title: Autoimmune myocarditis does not require B cells for antigen presentation.
Volume: 163
Issue: 10
Pages: 5265-8
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Publication
10973285 | J:118019
First Author: Bagley J
Year: 2000
Journal: Nat Immunol
Title: A critical role for interleukin 4 in activating alloreactive CD4 T cells.
Volume: 1
Issue: 3
Pages: 257-61
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Publication
16785496 | J:134411
First Author: Kryczek I
Year: 2006
Journal: J Immunol
Title: Cutting edge: induction of B7-H4 on APCs through IL-10: novel suppressive mode for regulatory T cells.
Volume: 177
Issue: 1
Pages: 40-4
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Publication
18664530 | J:140218
First Author: Burt BM
Year: 2008
Journal: J Leukoc Biol
Title: CD11c identifies a subset of murine liver natural killer cells that responds to adenoviral hepatitis.
Volume: 84
Issue: 4
Pages: 1039-46
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Publication
14980205 | J:89774
First Author: Guo H
Year: 2004
Journal: Neuron
Title: Activated protein C prevents neuronal apoptosis via protease activated receptors 1 and 3.
Volume: 41
Issue: 4
Pages: 563-72
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Publication
15308097 | J:93590
First Author: Shen L
Year: 2004
Journal: Immunity
Title: Important role of cathepsin S in generating peptides for TAP-independent MHC class I crosspresentation in vivo.
Volume: 21
Issue: 2
Pages: 155-65
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Publication
18328742 | J:132942
First Author: Strainic MG
Year: 2008
Journal: Immunity
Title: Locally produced complement fragments C5a and C3a provide both costimulatory and survival signals to naive CD4+ T cells.
Volume: 28
Issue: 3
Pages: 425-35
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Publication
10553046 | J:109516
First Author: Ozaki ME
Year: 1999
Journal: J Immunol
Title: CD4+ T cell responses to CD40-deficient APCs: defects in proliferation and negative selection apply only with B cells as APCs.
Volume: 163
Issue: 10
Pages: 5250-6
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Publication
9551964 | J:110946
First Author: Page DM
Year: 1998
Journal: J Immunol
Title: TNF receptor-deficient mice reveal striking differences between several models of thymocyte negative selection.
Volume: 160
Issue: 1
Pages: 120-33
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Publication
15137944 | J:90018
First Author: Amsen D
Year: 2004
Journal: Cell
Title: Instruction of distinct CD4 T helper cell fates by different notch ligands on antigen-presenting cells.
Volume: 117
Issue: 4
Pages: 515-26
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Publication
31420536 | J:279397
First Author: Han T
Year: 2019
Journal: Nat Commun
Title: Interplay between c-Src and the APC/C co-activator Cdh1 regulates mammary tumorigenesis.
Volume: 10
Issue: 1
Pages: 3716
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Publication
15657287 | J:95557
First Author: Schwarz A
Year: 2005
Journal: J Exp Med
Title: Prevention of UV radiation-induced immunosuppression by IL-12 is dependent on DNA repair.
Volume: 201
Issue: 2
Pages: 173-9
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Publication
20708155 | J:163673
First Author: Bennecke M
Year: 2010
Journal: Cancer Cell
Title: Ink4a/Arf and oncogene-induced senescence prevent tumor progression during alternative colorectal tumorigenesis.
Volume: 18
Issue: 2
Pages: 135-46
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Publication
34757798 | J:314666
First Author: Balasubramanian R
Year: 2021
Journal: Sci Adv
Title: Phase transition specified by a binary code patterns the vertebrate eye cup.
Volume: 7
Issue: 46
Pages: eabj9846
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Publication
26585400 | J:227252
First Author: Hayakawa Y
Year: 2015
Journal: Cancer Cell
Title: Mist1 Expressing Gastric Stem Cells Maintain the Normal and Neoplastic Gastric Epithelium and Are Supported by a Perivascular Stem Cell Niche.
Volume: 28
Issue: 6
Pages: 800-814
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Publication
20802149 | J:164214
First Author: Román E
Year: 2010
Journal: J Immunol
Title: Cutting edge: Hematopoietic-derived APCs select regulatory T cells in thymus.
Volume: 185
Issue: 7
Pages: 3819-23
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Publication
17475851 | J:146121
First Author: Yadav D
Year: 2007
Journal: J Immunol
Title: B7-2 regulates survival, phenotype, and function of APCs.
Volume: 178
Issue: 10
Pages: 6236-41
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Publication
15972649 | J:100581
First Author: Gruber A
Year: 2005
Journal: J Immunol
Title: MHC class I-positive dendritic cells (DC) control CD8 T cell homeostasis in vivo: T cell lymphopenia as a prerequisite for DC-mediated homeostatic proliferation of naive CD8 T cells.
Volume: 175
Issue: 1
Pages: 201-6
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Publication
18993085 | J:143180
First Author: Ebert PJ
Year: 2008
Journal: Immunity
Title: Low ligand requirement for deletion and lack of synapses in positive selection enforce the gauntlet of thymic T cell maturation.
Volume: 29
Issue: 5
Pages: 734-45
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Publication
14502286 | J:125600
First Author: Le Bon A
Year: 2003
Journal: Nat Immunol
Title: Cross-priming of CD8+ T cells stimulated by virus-induced type I interferon.
Volume: 4
Issue: 10
Pages: 1009-15
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Publication
22393151 | J:183087
First Author: Bai L
Year: 2012
Journal: J Immunol
Title: Distinct APCs explain the cytokine bias of α-galactosylceramide variants in vivo.
Volume: 188
Issue: 7
Pages: 3053-61
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Publication
30679199 | J:360148
 
First Author: Mundt S
Year: 2019
Journal: Sci Immunol
Title: Conventional DCs sample and present myelin antigens in the healthy CNS and allow parenchymal T cell entry to initiate neuroinflammation.
Volume: 4
Issue: 31
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Publication
29150240 | J:253563
First Author: Chang YH
Year: 2017
Journal: Immunity
Title: Dichotomous Expression of TNF Superfamily Ligands on Antigen-Presenting Cells Controls Post-priming Anti-viral CD4+ T Cell Immunity.
Volume: 47
Issue: 5
Pages: 943-958.e9
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Publication
29434238 | J:314188
First Author: Malo CS
Year: 2018
Journal: Nat Commun
Title: Non-equivalent antigen presenting capabilities of dendritic cells and macrophages in generating brain-infiltrating CD8 + T cell responses.
Volume: 9
Issue: 1
Pages: 633
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Publication
39358382 | J:357756
First Author: Patel S
Year: 2024
Journal: Nat Commun
Title: Transcription factor PATZ1 promotes adipogenesis by controlling promoter regulatory loci of adipogenic factors.
Volume: 15
Issue: 1
Pages: 8533
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Publication
16574431 | J:111937
First Author: Petros TJ
Year: 2006
Journal: Mol Cell Neurosci
Title: Temporal regulation of EphA4 in astroglia during murine retinal and optic nerve development.
Volume: 32
Issue: 1-2
Pages: 49-66
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Publication
12871644 | J:84581
First Author: Sanui T
Year: 2003
Journal: Immunity
Title: DOCK2 is essential for antigen-induced translocation of TCR and lipid rafts, but not PKC-theta and LFA-1, in T cells.
Volume: 19
Issue: 1
Pages: 119-29
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Publication
15528326 | J:94294
First Author: Zheng H
Year: 2004
Journal: J Immunol
Title: Cutting edge: cross-presentation of cell-associated antigens to MHC class I molecule is regulated by a major transcription factor for heat shock proteins.
Volume: 173
Issue: 10
Pages: 5929-33
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Publication
10485458 | J:57235
First Author: van Wezel T
Year: 1999
Journal: Cancer Res
Title: Four new colon cancer susceptibility loci, Scc6 to Scc9 in the mouse.
Volume: 59
Issue: 17
Pages: 4216-8
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Publication
33159073 | J:300813
First Author: Hilligan KL
Year: 2020
Journal: Nat Commun
Title: Dermal IRF4+ dendritic cells and monocytes license CD4+ T helper cells to distinct cytokine profiles.
Volume: 11
Issue: 1
Pages: 5637
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Publication
21173243 | J:169008
First Author: Iijima N
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Recruited inflammatory monocytes stimulate antiviral Th1 immunity in infected tissue.
Volume: 108
Issue: 1
Pages: 284-9
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Publication
17562817 | J:125874
First Author: Ehirchiou D
Year: 2007
Journal: J Exp Med
Title: CD11b facilitates the development of peripheral tolerance by suppressing Th17 differentiation.
Volume: 204
Issue: 7
Pages: 1519-24
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Publication
28432146 | J:247864
First Author: Ho NI
Year: 2017
Journal: J Immunol
Title: C1q-Dependent Dendritic Cell Cross-Presentation of In Vivo-Formed Antigen-Antibody Complexes.
Volume: 198
Issue: 11
Pages: 4235-4243
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Publication
17982464 | J:130271
First Author: Isermann B
Year: 2007
Journal: Nat Med
Title: Activated protein C protects against diabetic nephropathy by inhibiting endothelial and podocyte apoptosis.
Volume: 13
Issue: 11
Pages: 1349-58
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Publication
12707348 | J:82997
First Author: deSchoolmeester ML
Year: 2003
Journal: J Immunol
Title: Absence of CC chemokine ligand 2 results in an altered Th1/Th2 cytokine balance and failure to expel Trichuris muris infection.
Volume: 170
Issue: 9
Pages: 4693-700
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Publication
14724179 | J:87782
First Author: Wirth KG
Year: 2004
Journal: Genes Dev
Title: Loss of the anaphase-promoting complex in quiescent cells causes unscheduled hepatocyte proliferation.
Volume: 18
Issue: 1
Pages: 88-98
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Publication
29242645 | J:287431
First Author: Duan LJ
Year: 2017
Journal: Sci Rep
Title: Retinal Angiogenesis Regulates Astrocytic Differentiation in Neonatal Mouse Retinas by Oxygen Dependent Mechanisms.
Volume: 7
Issue: 1
Pages: 17608
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Publication
15048713 | J:88883
First Author: Judkowski V
Year: 2004
Journal: Eur J Immunol
Title: Increased islet antigen presentation leads to type-1 diabetes in mice with autoimmune susceptibility.
Volume: 34
Issue: 4
Pages: 1031-40
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Publication
16547236 | J:129897
First Author: Raimondi G
Year: 2006
Journal: J Immunol
Title: Induction of peripheral T cell tolerance by antigen-presenting B cells. I. Relevance of antigen presentation persistence.
Volume: 176
Issue: 7
Pages: 4012-20
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Publication
33027652 | J:299190
First Author: Hoghooghi V
Year: 2020
Journal: Cell Rep
Title: Cystatin C Plays a Sex-Dependent Detrimental Role in Experimental Autoimmune Encephalomyelitis.
Volume: 33
Issue: 1
Pages: 108236
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Publication
32171820 | J:293060
 
First Author: Terral G
Year: 2020
Journal: Neuroscience
Title: Synaptic Functions of Type-1 Cannabinoid Receptors in Inhibitory Circuits of the Anterior Piriform Cortex.
Volume: 433
Pages: 121-131
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Publication
17540840 | J:146406
First Author: Kowalska MA
Year: 2007
Journal: Blood
Title: Endogenous platelet factor 4 stimulates activated protein C generation in vivo and improves survival after thrombin or lipopolysaccharide challenge.
Volume: 110
Issue: 6
Pages: 1903-5
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Publication
15756646 | J:97821
First Author: Rodríguez-Pinto D
Year: 2005
Journal: Eur J Immunol
Title: B cells can prime naive CD4+ T cells in vivo in the absence of other professional antigen-presenting cells in a CD154-CD40-dependent manner.
Volume: 35
Issue: 4
Pages: 1097-105
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Publication
29186676 | J:269809
First Author: Aggarwal A
Year: 2017
Journal: Cell Rep
Title: The Circadian Clock Regulates Adipogenesis by a Per3 Crosstalk Pathway to Klf15.
Volume: 21
Issue: 9
Pages: 2367-2375
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Publication
23308247 | J:195892
First Author: Desel C
Year: 2013
Journal: PLoS One
Title: The Mincle-activating adjuvant TDB induces MyD88-dependent Th1 and Th17 responses through IL-1R signaling.
Volume: 8
Issue: 1
Pages: e53531
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Publication
33513345 | J:304131
First Author: Lin H
Year: 2021
Journal: Cancer Cell
Title: Stanniocalcin 1 is a phagocytosis checkpoint driving tumor immune resistance.
Volume: 39
Issue: 4
Pages: 480-493.e6
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Publication
22902234 | J:187367
First Author: Yogev N
Year: 2012
Journal: Immunity
Title: Dendritic cells ameliorate autoimmunity in the CNS by controlling the homeostasis of PD-1 receptor(+) regulatory T cells.
Volume: 37
Issue: 2
Pages: 264-75
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Publication
25458893 | J:232609
First Author: Krueger KC
Year: 2014
Journal: Stem Cell Reports
Title: Characterization of Cre recombinase activity for in vivo targeting of adipocyte precursor cells.
Volume: 3
Issue: 6
Pages: 1147-58
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Publication
12616499 | J:82412
First Author: Ardouin L
Year: 2003
Journal: Eur J Immunol
Title: Vav1 transduces TCR signals required for LFA-1 function and cell polarization at the immunological synapse.
Volume: 33
Issue: 3
Pages: 790-7
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Publication
28649987 | J:249946
 
First Author: Jiang Y
Year: 2017
Journal: Nat Commun
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