| Type |
Details |
Score |
| Publication |
| First Author: |
Ngo J |
| Year: |
2015 |
| Journal: |
Cell Death Dis |
| Title: |
Bax deficiency extends the survival of Ku70 knockout mice that develop lung and heart diseases. |
| Volume: |
6 |
|
| Pages: |
e1706 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Jones RG |
| Year: |
2007 |
| Journal: |
Immunity |
| Title: |
The proapoptotic factors Bax and Bak regulate T Cell proliferation through control of endoplasmic reticulum Ca(2+) homeostasis. |
| Volume: |
27 |
| Issue: |
2 |
| Pages: |
268-80 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mason KD |
| Year: |
2013 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Proapoptotic Bak and Bax guard against fatal systemic and organ-specific autoimmune disease. |
| Volume: |
110 |
| Issue: |
7 |
| Pages: |
2599-604 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Xiang H |
| Year: |
1998 |
| Journal: |
J Neurosci |
| Title: |
Bax involvement in p53-mediated neuronal cell death. |
| Volume: |
18 |
| Issue: |
4 |
| Pages: |
1363-73 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Hahn P |
| Year: |
2004 |
| Journal: |
Cell Death Differ |
| Title: |
Deficiency of Bax and Bak protects photoreceptors from light damage in vivo. |
| Volume: |
11 |
| Issue: |
11 |
| Pages: |
1192-7 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Lindsten T |
| Year: |
2006 |
| Journal: |
Cell Death Differ |
| Title: |
Cell death in the absence of Bax and Bak. |
| Volume: |
13 |
| Issue: |
8 |
| Pages: |
1272-6 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Duckworth CA |
| Year: |
2015 |
| Journal: |
Am J Physiol Gastrointest Liver Physiol |
| Title: |
bak deletion stimulates gastric epithelial proliferation and enhances Helicobacter felis-induced gastric atrophy and dysplasia in mice. |
| Volume: |
309 |
| Issue: |
6 |
| Pages: |
G420-30 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Zhao Y |
| Year: |
2001 |
| Journal: |
J Biol Chem |
| Title: |
Activation of pro-death Bcl-2 family proteins and mitochondria apoptosis pathway in tumor necrosis factor-alpha-induced liver injury. |
| Volume: |
276 |
| Issue: |
29 |
| Pages: |
27432-40 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Ferrer PE |
| Year: |
2012 |
| Journal: |
PLoS One |
| Title: |
Translocation of a Bak C-terminus mutant from cytosol to mitochondria to mediate cytochrome C release: implications for Bak and Bax apoptotic function. |
| Volume: |
7 |
| Issue: |
3 |
| Pages: |
e31510 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Lindsten T |
| Year: |
2000 |
| Journal: |
Mol Cell |
| Title: |
The combined functions of proapoptotic Bcl-2 family members bak and bax are essential for normal development of multiple tissues. |
| Volume: |
6 |
| Issue: |
6 |
| Pages: |
1389-99 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Guo T |
| Year: |
2011 |
| Journal: |
Nat Neurosci |
| Title: |
An evolving NGF-Hoxd1 signaling pathway mediates development of divergent neural circuits in vertebrates. |
| Volume: |
14 |
| Issue: |
1 |
| Pages: |
31-6 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Lum JJ |
| Year: |
2005 |
| Journal: |
Cell |
| Title: |
Growth factor regulation of autophagy and cell survival in the absence of apoptosis. |
| Volume: |
120 |
| Issue: |
2 |
| Pages: |
237-48 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Middleton G |
| Year: |
2001 |
| Journal: |
Development |
| Title: |
Populations of NGF-dependent neurones differ in their requirement for BAX to undergo apoptosis in the absence of NGF/TrkA signalling in vivo. |
| Volume: |
128 |
| Issue: |
23 |
| Pages: |
4715-28 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Xiang C |
| Year: |
2010 |
| Journal: |
Mol Cell Neurosci |
| Title: |
The transcription factor, Lmx1b, is necessary for the development of the principal trigeminal nucleus-based lemniscal pathway. |
| Volume: |
44 |
| Issue: |
4 |
| Pages: |
394-403 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Keeley PW |
| Year: |
2014 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Pituitary tumor-transforming gene 1 regulates the patterning of retinal mosaics. |
| Volume: |
111 |
| Issue: |
25 |
| Pages: |
9295-300 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Lindsten T |
| Year: |
2003 |
| Journal: |
J Neurosci |
| Title: |
The proapoptotic activities of Bax and Bak limit the size of the neural stem cell pool. |
| Volume: |
23 |
| Issue: |
35 |
| Pages: |
11112-9 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kawai K |
| Year: |
2009 |
| Journal: |
Eur J Neurosci |
| Title: |
Maintenance of the relative proportion of oligodendrocytes to axons even in the absence of BAX and BAK. |
| Volume: |
30 |
| Issue: |
11 |
| Pages: |
2030-41 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Owens TW |
| Year: |
2010 |
| Journal: |
J Biol Chem |
| Title: |
Role for X-linked Inhibitor of apoptosis protein upstream of mitochondrial permeabilization. |
| Volume: |
285 |
| Issue: |
2 |
| Pages: |
1081-8 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Eischen CM |
| Year: |
2002 |
| Journal: |
Cancer Res |
| Title: |
Loss of Bax alters tumor spectrum and tumor numbers in ARF-deficient mice. |
| Volume: |
62 |
| Issue: |
7 |
| Pages: |
2184-91 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Hahn P |
| Year: |
2005 |
| Journal: |
Arch Ophthalmol |
| Title: |
Persistent fetal ocular vasculature in mice deficient in bax and bak. |
| Volume: |
123 |
| Issue: |
6 |
| Pages: |
797-802 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Wolpaw AJ |
| Year: |
2011 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Modulatory profiling identifies mechanisms of small molecule-induced cell death. |
| Volume: |
108 |
| Issue: |
39 |
| Pages: |
E771-80 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Bouilloux F |
| Year: |
2016 |
| Journal: |
Elife |
| Title: |
Loss of the transcription factor Meis1 prevents sympathetic neurons target-field innervation and increases susceptibility to sudden cardiac death. |
| Volume: |
5 |
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Zhuang Y |
| Year: |
2016 |
| Journal: |
J Virol |
| Title: |
Mitochondrial p53 Contributes to Reovirus-Induced Neuronal Apoptosis and Central Nervous System Injury in a Mouse Model of Viral Encephalitis. |
| Volume: |
90 |
| Issue: |
17 |
| Pages: |
7684-91 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Eischen CM |
| Year: |
2001 |
| Journal: |
Mol Cell Biol |
| Title: |
Bax loss impairs Myc-induced apoptosis and circumvents the selection of p53 mutations during Myc-mediated lymphomagenesis. |
| Volume: |
21 |
| Issue: |
22 |
| Pages: |
7653-62 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Fontanini A |
| Year: |
2009 |
| Journal: |
J Biol Chem |
| Title: |
The Isopeptidase Inhibitor G5 Triggers a Caspase-independent Necrotic Death in Cells Resistant to Apoptosis: A COMPARATIVE STUDY WITH THE PROTEASOME INHIBITOR BORTEZOMIB. |
| Volume: |
284 |
| Issue: |
13 |
| Pages: |
8369-81 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Cleland MM |
| Year: |
2011 |
| Journal: |
Cell Death Differ |
| Title: |
Bcl-2 family interaction with the mitochondrial morphogenesis machinery. |
| Volume: |
18 |
| Issue: |
2 |
| Pages: |
235-47 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Garcia I |
| Year: |
2013 |
| Journal: |
Oncogene |
| Title: |
Bax deficiency prolongs cerebellar neurogenesis, accelerates medulloblastoma formation and paradoxically increases both malignancy and differentiation. |
| Volume: |
32 |
| Issue: |
18 |
| Pages: |
2304-14 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Karbowski M |
| Year: |
2006 |
| Journal: |
Nature |
| Title: |
Role of Bax and Bak in mitochondrial morphogenesis. |
| Volume: |
443 |
| Issue: |
7112 |
| Pages: |
658-62 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Pronk CJ |
| Year: |
2011 |
| Journal: |
J Exp Med |
| Title: |
Tumor necrosis factor restricts hematopoietic stem cell activity in mice: involvement of two distinct receptors. |
| Volume: |
208 |
| Issue: |
8 |
| Pages: |
1563-70 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
McPherson JP |
| Year: |
2006 |
| Journal: |
Hum Mol Genet |
| Title: |
A role for Brca1 in chromosome end maintenance. |
| Volume: |
15 |
| Issue: |
6 |
| Pages: |
831-8 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Lee H |
| Year: |
2012 |
| Journal: |
J Immunol |
| Title: |
A p53 axis regulates B cell receptor-triggered, innate immune system-driven B cell clonal expansion. |
| Volume: |
188 |
| Issue: |
12 |
| Pages: |
6093-108 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Marsden VS |
| Year: |
2006 |
| Journal: |
Blood |
| Title: |
Apaf-1 and caspase-9 are required for cytokine withdrawal-induced apoptosis of mast cells but dispensable for their functional and clonogenic death. |
| Volume: |
107 |
| Issue: |
5 |
| Pages: |
1872-7 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
von Muenchow L |
| Year: |
2017 |
| Journal: |
Eur J Immunol |
| Title: |
Pro-B cells propagated in stromal cell-free cultures reconstitute functional B-cell compartments in immunodeficient mice. |
| Volume: |
47 |
| Issue: |
2 |
| Pages: |
394-405 |
|
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•
•
•
•
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| First Author: |
Huang X |
| Year: |
2004 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Homeostatic cell-cycle control by BLyS: Induction of cell-cycle entry but not G1/S transition in opposition to p18INK4c and p27Kip1. |
| Volume: |
101 |
| Issue: |
51 |
| Pages: |
17789-94 |
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•
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| First Author: |
Huang Z |
| Year: |
2006 |
| Journal: |
J Immunol |
| Title: |
Transcriptional regulation of CD4 gene expression by T cell factor-1/beta-catenin pathway. |
| Volume: |
176 |
| Issue: |
8 |
| Pages: |
4880-7 |
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•
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| First Author: |
Thompson LF |
| Year: |
2000 |
| Journal: |
J Clin Invest |
| Title: |
Metabolites from apoptotic thymocytes inhibit thymopoiesis in adenosine deaminase-deficient fetal thymic organ cultures. |
| Volume: |
106 |
| Issue: |
9 |
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1149-57 |
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| First Author: |
Ortega-Molina A |
| Year: |
2015 |
| Journal: |
Nat Med |
| Title: |
The histone lysine methyltransferase KMT2D sustains a gene expression program that represses B cell lymphoma development. |
| Volume: |
21 |
| Issue: |
10 |
| Pages: |
1199-208 |
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| First Author: |
Ebner F |
| Year: |
2017 |
| Journal: |
J Clin Invest |
| Title: |
The RNA-binding protein tristetraprolin schedules apoptosis of pathogen-engaged neutrophils during bacterial infection. |
| Volume: |
127 |
| Issue: |
6 |
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2051-2065 |
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| First Author: |
Xu J |
| Year: |
2023 |
| Journal: |
Cell Rep |
| Title: |
Constitutively active autophagy in macrophages dampens inflammation through metabolic and post-transcriptional regulation of cytokine production. |
| Volume: |
42 |
| Issue: |
7 |
| Pages: |
112708 |
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| First Author: |
Kueh HY |
| Year: |
2016 |
| Journal: |
Nat Immunol |
| Title: |
Asynchronous combinatorial action of four regulatory factors activates Bcl11b for T cell commitment. |
| Volume: |
17 |
| Issue: |
8 |
| Pages: |
956-65 |
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| First Author: |
Ferch U |
| Year: |
2007 |
| Journal: |
Nat Immunol |
| Title: |
MALT1 directs B cell receptor-induced canonical nuclear factor-kappaB signaling selectively to the c-Rel subunit. |
| Volume: |
8 |
| Issue: |
9 |
| Pages: |
984-91 |
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•
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| First Author: |
Weisleder N |
| Year: |
2004 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Bcl-2 overexpression corrects mitochondrial defects and ameliorates inherited desmin null cardiomyopathy. |
| Volume: |
101 |
| Issue: |
3 |
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769-74 |
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Grigoriadis G |
| Year: |
2011 |
| Journal: |
PLoS One |
| Title: |
c-Rel controls multiple discrete steps in the thymic development of Foxp3+ CD4 regulatory T cells. |
| Volume: |
6 |
| Issue: |
10 |
| Pages: |
e26851 |
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| Strain |
| Attribute String: |
congenic, major histocompatibility congenic, mutant strain, targeted mutation, transgenic |
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•
•
•
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| First Author: |
Wong WF |
| Year: |
2015 |
| Journal: |
Mol Immunol |
| Title: |
The artificial loss of Runx1 reduces the expression of quiescence-associated transcription factors in CD4(+) T lymphocytes. |
| Volume: |
68 |
| Issue: |
2 Pt A |
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223-33 |
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Becker SM |
| Year: |
2010 |
| Journal: |
Am J Pathol |
| Title: |
Epithelial cell apoptosis facilitates Entamoeba histolytica infection in the gut. |
| Volume: |
176 |
| Issue: |
3 |
| Pages: |
1316-22 |
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•
•
•
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Petschner F |
| Year: |
1998 |
| Journal: |
Eur J Immunol |
| Title: |
Constitutive expression of Bcl-xL or Bcl-2 prevents peptide antigen-induced T cell deletion but does not influence T cell homeostasis after a viral infection. |
| Volume: |
28 |
| Issue: |
2 |
| Pages: |
560-9 |
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| First Author: |
Liu X |
| Year: |
2004 |
| Journal: |
Nat Immunol |
| Title: |
Duration of TCR signaling controls CD4-CD8 lineage differentiation in vivo. |
| Volume: |
5 |
| Issue: |
3 |
| Pages: |
280-8 |
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•
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| First Author: |
Brunelle JK |
| Year: |
2009 |
| Journal: |
J Cell Biol |
| Title: |
MCL-1-dependent leukemia cells are more sensitive to chemotherapy than BCL-2-dependent counterparts. |
| Volume: |
187 |
| Issue: |
3 |
| Pages: |
429-42 |
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•
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| First Author: |
Williams O |
| Year: |
1998 |
| Journal: |
J Exp Med |
| Title: |
The action of Bax and bcl-2 on T cell selection. |
| Volume: |
188 |
| Issue: |
6 |
| Pages: |
1125-33 |
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•
•
•
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| First Author: |
González J |
| Year: |
2007 |
| Journal: |
J Immunol |
| Title: |
CD4+CD25+ T cell-dependent inhibition of autoimmunity in transgenic mice overexpressing human Bcl-2 in T lymphocytes. |
| Volume: |
178 |
| Issue: |
5 |
| Pages: |
2778-86 |
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•
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| First Author: |
Strasser A |
| Year: |
1990 |
| Journal: |
Curr Top Microbiol Immunol |
| Title: |
Abnormalities of the immune system induced by dysregulated bcl-2 expression in transgenic mice. |
| Volume: |
166 |
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| Pages: |
175-81 |
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•
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| First Author: |
Verkoczy L |
| Year: |
2011 |
| Journal: |
J Immunol |
| Title: |
Rescue of HIV-1 broad neutralizing antibody-expressing B cells in 2F5 VH x VL knockin mice reveals multiple tolerance controls. |
| Volume: |
187 |
| Issue: |
7 |
| Pages: |
3785-97 |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
mutant strain, congenic, transposon induced mutation |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
transposition, mutant strain |
|
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•
•
•
•
|
| Publication |
| First Author: |
Delgado Lagos F |
| Year: |
2021 |
| Journal: |
Blood |
| Title: |
Secreted modular calcium-binding protein 1 binds and activates thrombin to account for platelet hyperreactivity in diabetes. |
| Volume: |
137 |
| Issue: |
12 |
| Pages: |
1641-1651 |
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•
•
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•
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| First Author: |
Ishisaka M |
| Year: |
2012 |
| Journal: |
PLoS One |
| Title: |
Diacylglycerol kinase β knockout mice exhibit attention-deficit behavior and an abnormal response on methylphenidate-induced hyperactivity. |
| Volume: |
7 |
| Issue: |
5 |
| Pages: |
e37058 |
|
•
•
•
•
•
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| Publication |
| First Author: |
Hozumi Y |
| Year: |
2015 |
| Journal: |
Brain Res |
| Title: |
Involvement of diacylglycerol kinase β in the spine formation at distal dendrites of striatal medium spiny neurons. |
| Volume: |
1594 |
|
| Pages: |
36-45 |
|
•
•
•
•
•
|
| Allele |
| Name: |
transgene insertion 1, Philippe Lesnik |
| Allele Type: |
Transgenic |
| Attribute String: |
Inserted expressed sequence |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Nikouee A |
| Year: |
2021 |
| Journal: |
Front Cell Infect Microbiol |
| Title: |
Beclin-1-Dependent Autophagy Improves Outcomes of Pneumonia-Induced Sepsis. |
| Volume: |
11 |
|
| Pages: |
706637 |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Bak1/Bak1 Bax/Bax |
| Background: |
involves: 129S1/Sv * 129S1/SvImJ * 129X1/SvJ * C57BL/6 |
| Zygosity: |
cx |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Dnmt1/Dnmt1<+> Tg(IghMyc)22Bri/? Tg(MMTVtTA)1Mam/? |
| Background: |
involves: 129S4/SvJae * C57BL/6 |
| Zygosity: |
cx |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Arpc3/Arpc3 |
| Background: |
involves: C3H * C57BL * C57BL/6 * DBA |
| Zygosity: |
hm |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Bax/Bax Ntrk1/Ntrk1 |
| Background: |
involves: 129S1/Sv * 129X1/SvJ |
| Zygosity: |
cx |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Arpc3/Arpc3 |
| Background: |
Not Specified |
| Zygosity: |
hm |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Bax/Bax<+> Nanos2/Nanos2 |
| Background: |
involves: 129S1/Sv * 129X1/SvJ |
| Zygosity: |
cx |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Bax/Bax Nanos2/Nanos2 |
| Background: |
involves: 129S1/Sv * 129X1/SvJ |
| Zygosity: |
cx |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Pik3cd/Pik3cd Tg(BCL2)36Wehi/? |
| Background: |
involves: 129S4/SvJae * C57BL/6JWehi * SJL/JWehi |
| Zygosity: |
cx |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Bak1/Bak1 Bax/Bax |
| Background: |
involves: 129S1/Sv * 129X1/SvJ |
| Zygosity: |
cx |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Bax/Bax Ntrk1/Ntrk1 |
| Background: |
involves: 129S1/Sv * 129X1/SvJ |
| Zygosity: |
cx |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Cd79b/Cd79b Tg(BCL2)22Wehi/? Tg(Rag2-Igb)1Mnz/? |
| Background: |
involves: 129S1/Sv * C57BL/6JWehi * SJL/JWehi |
| Zygosity: |
cx |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Dgkb/Dgkb |
| Background: |
involves: C3H * C57BL/6 * DBA/2 * ICR |
| Zygosity: |
hm |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Igh-J/Igh-J Igk-J/Igk-J Tg(BCL2)22Wehi/? |
| Background: |
involves: C57BL/6JWehi * SJL/JWehi |
| Zygosity: |
cx |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Cbln1/Cbln1 Bax/Bax |
| Background: |
involves: 129S7/SvEvBrd * 129X1/SvJ |
| Zygosity: |
cx |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Ebf1/Ebf1 Polr2a/Polr2a<+> Tg(BCL2)#Wehi/? |
| Background: |
involves: C57BL/6 * C57BL/6JWehi * SJL * SJL/JWehi |
| Zygosity: |
cn |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Bax/Bax Del(18Pcdhg)1Xzw/Del(18Pcdhg)1Xzw |
| Background: |
involves: 129X1/SvJ |
| Zygosity: |
cx |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Tg(BCL2)25Wehi/? Tg(Igkv3-5*-MYC)#Plbe/? |
| Background: |
involves: C57BL/6 * C57BL/6JWehi * SJL/JWehi |
| Zygosity: |
cx |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Sppl2a/Sppl2a Tg(Vav-BCL2)69Jad/? |
| Background: |
involves: C57BL/6JAnu |
| Zygosity: |
cx |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Bax/Bax Etv1/Etv1 |
| Background: |
involves: 129S1/Sv * 129X1/SvJ |
| Zygosity: |
cx |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Dgkb/Dgkb |
| Background: |
involves: C3H * C57BL/6 * C57BL/6N * DBA/2 * ICR |
| Zygosity: |
hm |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Prkd2/Prkd2 Prkd3/Prkd3 Tg(BCL2)25Wehi/? Tg(Lck-cre)1Jtak/? |
| Background: |
involves: 129 * C57BL/6 * C57BL/6JWehi * SJL/JWehi |
| Zygosity: |
cn |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Bak1/Bak1 Bax/Bax |
| Background: |
B6.129-Bax Bak1 |
| Zygosity: |
cx |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Bax/Bax Mcl1/Mcl1 Tg(Nes-cre)2472Pick/? |
| Background: |
involves: 129X1/SvJ * C57BL/6J * FVB/N |
| Zygosity: |
cn |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Bax/Bax<+> Creb1/Creb1<+> |
| Background: |
involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6 |
| Zygosity: |
cx |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Bax/Bax Creb1/Creb1<+> |
| Background: |
involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6 |
| Zygosity: |
cx |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Bax/Bax Creb1/Creb1 |
| Background: |
involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6 |
| Zygosity: |
cx |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Bax/Bax Tg(Hlxb9-GFP)1Tmj/? |
| Background: |
involves: C57BL/6J * CBA |
| Zygosity: |
cx |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Wright T |
| Year: |
2024 |
| Journal: |
Mol Cell |
| Title: |
Anti-apoptotic MCL-1 promotes long-chain fatty acid oxidation through interaction with ACSL1. |
| Volume: |
84 |
| Issue: |
7 |
| Pages: |
1338-1353.e8 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kang SJ |
| Year: |
2008 |
| Journal: |
Immunity |
| Title: |
Regulation of hierarchical clustering and activation of innate immune cells by dendritic cells. |
| Volume: |
29 |
| Issue: |
5 |
| Pages: |
819-33 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Bonilla-Claudio M |
| Year: |
2012 |
| Journal: |
Development |
| Title: |
Bmp signaling regulates a dose-dependent transcriptional program to control facial skeletal development. |
| Volume: |
139 |
| Issue: |
4 |
| Pages: |
709-19 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Ulmke PA |
| Year: |
2021 |
| Journal: |
Development |
| Title: |
Post-transcriptional regulation by the exosome complex is required for cell survival and forebrain development via repression of P53 signaling. |
| Volume: |
148 |
| Issue: |
3 |
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Yang P |
| Year: |
2019 |
| Journal: |
Nat Commun |
| Title: |
Tip60- and sirtuin 2-regulated MARCKS acetylation and phosphorylation are required for diabetic embryopathy. |
| Volume: |
10 |
| Issue: |
1 |
| Pages: |
282 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Spruce T |
| Year: |
2010 |
| Journal: |
Dev Cell |
| Title: |
An early developmental role for miRNAs in the maintenance of extraembryonic stem cells in the mouse embryo. |
| Volume: |
19 |
| Issue: |
2 |
| Pages: |
207-19 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Yao F |
| Year: |
2023 |
| Journal: |
Cell Death Dis |
| Title: |
Deletion of ARGLU1 causes global defects in alternative splicing in vivo and mouse cortical malformations primarily via apoptosis. |
| Volume: |
14 |
| Issue: |
8 |
| Pages: |
543 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Phua YL |
| Year: |
2015 |
| Journal: |
Physiol Rep |
| Title: |
Renal stromal miRNAs are required for normal nephrogenesis and glomerular mesangial survival. |
| Volume: |
3 |
| Issue: |
10 |
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Yang SL |
| Year: |
2015 |
| Journal: |
Dev Biol |
| Title: |
MiR-302/367 regulate neural progenitor proliferation, differentiation timing, and survival in neurulation. |
| Volume: |
408 |
| Issue: |
1 |
| Pages: |
140-50 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Woodland RT |
| Year: |
2008 |
| Journal: |
Blood |
| Title: |
Multiple signaling pathways promote B lymphocyte stimulator dependent B-cell growth and survival. |
| Volume: |
111 |
| Issue: |
2 |
| Pages: |
750-60 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Ku B |
| Year: |
2011 |
| Journal: |
Cell Res |
| Title: |
Evidence that inhibition of BAX activation by BCL-2 involves its tight and preferential interaction with the BH3 domain of BAX. |
| Volume: |
21 |
| Issue: |
4 |
| Pages: |
627-41 |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
167
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
165
 |
| Fragment?: |
false |
|
•
•
•
•
•
|