|  Help  |  About  |  Contact Us

Search our database by keyword

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 3601 to 3700 out of 4701 for Bcl2

0.031s

Categories

Hits by Pathway

Hits by Category

Hits by Strain

Type Details Score
Publication  
First Author: Ngo J
Year: 2015
Journal: Cell Death Dis
Title: Bax deficiency extends the survival of Ku70 knockout mice that develop lung and heart diseases.
Volume: 6
Pages: e1706
Publication
First Author: Jones RG
Year: 2007
Journal: Immunity
Title: The proapoptotic factors Bax and Bak regulate T Cell proliferation through control of endoplasmic reticulum Ca(2+) homeostasis.
Volume: 27
Issue: 2
Pages: 268-80
Publication
First Author: Mason KD
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Proapoptotic Bak and Bax guard against fatal systemic and organ-specific autoimmune disease.
Volume: 110
Issue: 7
Pages: 2599-604
Publication
First Author: Xiang H
Year: 1998
Journal: J Neurosci
Title: Bax involvement in p53-mediated neuronal cell death.
Volume: 18
Issue: 4
Pages: 1363-73
Publication
First Author: Hahn P
Year: 2004
Journal: Cell Death Differ
Title: Deficiency of Bax and Bak protects photoreceptors from light damage in vivo.
Volume: 11
Issue: 11
Pages: 1192-7
Publication
First Author: Lindsten T
Year: 2006
Journal: Cell Death Differ
Title: Cell death in the absence of Bax and Bak.
Volume: 13
Issue: 8
Pages: 1272-6
Publication
First Author: Duckworth CA
Year: 2015
Journal: Am J Physiol Gastrointest Liver Physiol
Title: bak deletion stimulates gastric epithelial proliferation and enhances Helicobacter felis-induced gastric atrophy and dysplasia in mice.
Volume: 309
Issue: 6
Pages: G420-30
Publication
First Author: Zhao Y
Year: 2001
Journal: J Biol Chem
Title: Activation of pro-death Bcl-2 family proteins and mitochondria apoptosis pathway in tumor necrosis factor-alpha-induced liver injury.
Volume: 276
Issue: 29
Pages: 27432-40
Publication
First Author: Ferrer PE
Year: 2012
Journal: PLoS One
Title: Translocation of a Bak C-terminus mutant from cytosol to mitochondria to mediate cytochrome C release: implications for Bak and Bax apoptotic function.
Volume: 7
Issue: 3
Pages: e31510
Publication
First Author: Lindsten T
Year: 2000
Journal: Mol Cell
Title: The combined functions of proapoptotic Bcl-2 family members bak and bax are essential for normal development of multiple tissues.
Volume: 6
Issue: 6
Pages: 1389-99
Publication
First Author: Guo T
Year: 2011
Journal: Nat Neurosci
Title: An evolving NGF-Hoxd1 signaling pathway mediates development of divergent neural circuits in vertebrates.
Volume: 14
Issue: 1
Pages: 31-6
Publication
First Author: Lum JJ
Year: 2005
Journal: Cell
Title: Growth factor regulation of autophagy and cell survival in the absence of apoptosis.
Volume: 120
Issue: 2
Pages: 237-48
Publication
First Author: Middleton G
Year: 2001
Journal: Development
Title: Populations of NGF-dependent neurones differ in their requirement for BAX to undergo apoptosis in the absence of NGF/TrkA signalling in vivo.
Volume: 128
Issue: 23
Pages: 4715-28
Publication
First Author: Xiang C
Year: 2010
Journal: Mol Cell Neurosci
Title: The transcription factor, Lmx1b, is necessary for the development of the principal trigeminal nucleus-based lemniscal pathway.
Volume: 44
Issue: 4
Pages: 394-403
Publication
First Author: Keeley PW
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Pituitary tumor-transforming gene 1 regulates the patterning of retinal mosaics.
Volume: 111
Issue: 25
Pages: 9295-300
Publication
First Author: Lindsten T
Year: 2003
Journal: J Neurosci
Title: The proapoptotic activities of Bax and Bak limit the size of the neural stem cell pool.
Volume: 23
Issue: 35
Pages: 11112-9
Publication
First Author: Kawai K
Year: 2009
Journal: Eur J Neurosci
Title: Maintenance of the relative proportion of oligodendrocytes to axons even in the absence of BAX and BAK.
Volume: 30
Issue: 11
Pages: 2030-41
Publication
First Author: Owens TW
Year: 2010
Journal: J Biol Chem
Title: Role for X-linked Inhibitor of apoptosis protein upstream of mitochondrial permeabilization.
Volume: 285
Issue: 2
Pages: 1081-8
Publication
First Author: Eischen CM
Year: 2002
Journal: Cancer Res
Title: Loss of Bax alters tumor spectrum and tumor numbers in ARF-deficient mice.
Volume: 62
Issue: 7
Pages: 2184-91
Publication
First Author: Hahn P
Year: 2005
Journal: Arch Ophthalmol
Title: Persistent fetal ocular vasculature in mice deficient in bax and bak.
Volume: 123
Issue: 6
Pages: 797-802
Publication
First Author: Wolpaw AJ
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Modulatory profiling identifies mechanisms of small molecule-induced cell death.
Volume: 108
Issue: 39
Pages: E771-80
Publication    
First Author: Bouilloux F
Year: 2016
Journal: Elife
Title: Loss of the transcription factor Meis1 prevents sympathetic neurons target-field innervation and increases susceptibility to sudden cardiac death.
Volume: 5
Publication
First Author: Zhuang Y
Year: 2016
Journal: J Virol
Title: Mitochondrial p53 Contributes to Reovirus-Induced Neuronal Apoptosis and Central Nervous System Injury in a Mouse Model of Viral Encephalitis.
Volume: 90
Issue: 17
Pages: 7684-91
Publication
First Author: Eischen CM
Year: 2001
Journal: Mol Cell Biol
Title: Bax loss impairs Myc-induced apoptosis and circumvents the selection of p53 mutations during Myc-mediated lymphomagenesis.
Volume: 21
Issue: 22
Pages: 7653-62
Publication
First Author: Fontanini A
Year: 2009
Journal: J Biol Chem
Title: The Isopeptidase Inhibitor G5 Triggers a Caspase-independent Necrotic Death in Cells Resistant to Apoptosis: A COMPARATIVE STUDY WITH THE PROTEASOME INHIBITOR BORTEZOMIB.
Volume: 284
Issue: 13
Pages: 8369-81
Publication
First Author: Cleland MM
Year: 2011
Journal: Cell Death Differ
Title: Bcl-2 family interaction with the mitochondrial morphogenesis machinery.
Volume: 18
Issue: 2
Pages: 235-47
Publication
First Author: Garcia I
Year: 2013
Journal: Oncogene
Title: Bax deficiency prolongs cerebellar neurogenesis, accelerates medulloblastoma formation and paradoxically increases both malignancy and differentiation.
Volume: 32
Issue: 18
Pages: 2304-14
Publication
First Author: Karbowski M
Year: 2006
Journal: Nature
Title: Role of Bax and Bak in mitochondrial morphogenesis.
Volume: 443
Issue: 7112
Pages: 658-62
Publication
First Author: Pronk CJ
Year: 2011
Journal: J Exp Med
Title: Tumor necrosis factor restricts hematopoietic stem cell activity in mice: involvement of two distinct receptors.
Volume: 208
Issue: 8
Pages: 1563-70
Publication
First Author: McPherson JP
Year: 2006
Journal: Hum Mol Genet
Title: A role for Brca1 in chromosome end maintenance.
Volume: 15
Issue: 6
Pages: 831-8
Publication
First Author: Lee H
Year: 2012
Journal: J Immunol
Title: A p53 axis regulates B cell receptor-triggered, innate immune system-driven B cell clonal expansion.
Volume: 188
Issue: 12
Pages: 6093-108
Publication
First Author: Marsden VS
Year: 2006
Journal: Blood
Title: Apaf-1 and caspase-9 are required for cytokine withdrawal-induced apoptosis of mast cells but dispensable for their functional and clonogenic death.
Volume: 107
Issue: 5
Pages: 1872-7
Publication
First Author: von Muenchow L
Year: 2017
Journal: Eur J Immunol
Title: Pro-B cells propagated in stromal cell-free cultures reconstitute functional B-cell compartments in immunodeficient mice.
Volume: 47
Issue: 2
Pages: 394-405
Publication
First Author: Huang X
Year: 2004
Journal: Proc Natl Acad Sci U S A
Title: Homeostatic cell-cycle control by BLyS: Induction of cell-cycle entry but not G1/S transition in opposition to p18INK4c and p27Kip1.
Volume: 101
Issue: 51
Pages: 17789-94
Publication
First Author: Huang Z
Year: 2006
Journal: J Immunol
Title: Transcriptional regulation of CD4 gene expression by T cell factor-1/beta-catenin pathway.
Volume: 176
Issue: 8
Pages: 4880-7
Publication
First Author: Thompson LF
Year: 2000
Journal: J Clin Invest
Title: Metabolites from apoptotic thymocytes inhibit thymopoiesis in adenosine deaminase-deficient fetal thymic organ cultures.
Volume: 106
Issue: 9
Pages: 1149-57
Publication
First Author: Ortega-Molina A
Year: 2015
Journal: Nat Med
Title: The histone lysine methyltransferase KMT2D sustains a gene expression program that represses B cell lymphoma development.
Volume: 21
Issue: 10
Pages: 1199-208
Publication
First Author: Ebner F
Year: 2017
Journal: J Clin Invest
Title: The RNA-binding protein tristetraprolin schedules apoptosis of pathogen-engaged neutrophils during bacterial infection.
Volume: 127
Issue: 6
Pages: 2051-2065
Publication
First Author: Xu J
Year: 2023
Journal: Cell Rep
Title: Constitutively active autophagy in macrophages dampens inflammation through metabolic and post-transcriptional regulation of cytokine production.
Volume: 42
Issue: 7
Pages: 112708
Publication
First Author: Kueh HY
Year: 2016
Journal: Nat Immunol
Title: Asynchronous combinatorial action of four regulatory factors activates Bcl11b for T cell commitment.
Volume: 17
Issue: 8
Pages: 956-65
Publication
First Author: Ferch U
Year: 2007
Journal: Nat Immunol
Title: MALT1 directs B cell receptor-induced canonical nuclear factor-kappaB signaling selectively to the c-Rel subunit.
Volume: 8
Issue: 9
Pages: 984-91
Publication
First Author: Weisleder N
Year: 2004
Journal: Proc Natl Acad Sci U S A
Title: Bcl-2 overexpression corrects mitochondrial defects and ameliorates inherited desmin null cardiomyopathy.
Volume: 101
Issue: 3
Pages: 769-74
Publication
First Author: Grigoriadis G
Year: 2011
Journal: PLoS One
Title: c-Rel controls multiple discrete steps in the thymic development of Foxp3+ CD4 regulatory T cells.
Volume: 6
Issue: 10
Pages: e26851
Strain
Attribute String: congenic, major histocompatibility congenic, mutant strain, targeted mutation, transgenic
Publication
First Author: Wong WF
Year: 2015
Journal: Mol Immunol
Title: The artificial loss of Runx1 reduces the expression of quiescence-associated transcription factors in CD4(+) T lymphocytes.
Volume: 68
Issue: 2 Pt A
Pages: 223-33
Publication
First Author: Becker SM
Year: 2010
Journal: Am J Pathol
Title: Epithelial cell apoptosis facilitates Entamoeba histolytica infection in the gut.
Volume: 176
Issue: 3
Pages: 1316-22
Publication
First Author: Petschner F
Year: 1998
Journal: Eur J Immunol
Title: Constitutive expression of Bcl-xL or Bcl-2 prevents peptide antigen-induced T cell deletion but does not influence T cell homeostasis after a viral infection.
Volume: 28
Issue: 2
Pages: 560-9
Publication
First Author: Liu X
Year: 2004
Journal: Nat Immunol
Title: Duration of TCR signaling controls CD4-CD8 lineage differentiation in vivo.
Volume: 5
Issue: 3
Pages: 280-8
Publication
First Author: Brunelle JK
Year: 2009
Journal: J Cell Biol
Title: MCL-1-dependent leukemia cells are more sensitive to chemotherapy than BCL-2-dependent counterparts.
Volume: 187
Issue: 3
Pages: 429-42
Publication
First Author: Williams O
Year: 1998
Journal: J Exp Med
Title: The action of Bax and bcl-2 on T cell selection.
Volume: 188
Issue: 6
Pages: 1125-33
Publication
First Author: González J
Year: 2007
Journal: J Immunol
Title: CD4+CD25+ T cell-dependent inhibition of autoimmunity in transgenic mice overexpressing human Bcl-2 in T lymphocytes.
Volume: 178
Issue: 5
Pages: 2778-86
Publication  
First Author: Strasser A
Year: 1990
Journal: Curr Top Microbiol Immunol
Title: Abnormalities of the immune system induced by dysregulated bcl-2 expression in transgenic mice.
Volume: 166
Pages: 175-81
Publication
First Author: Verkoczy L
Year: 2011
Journal: J Immunol
Title: Rescue of HIV-1 broad neutralizing antibody-expressing B cells in 2F5 VH x VL knockin mice reveals multiple tolerance controls.
Volume: 187
Issue: 7
Pages: 3785-97
Strain
Attribute String: mutant strain, congenic, transposon induced mutation
Strain
Attribute String: transposition, mutant strain
Publication
First Author: Delgado Lagos F
Year: 2021
Journal: Blood
Title: Secreted modular calcium-binding protein 1 binds and activates thrombin to account for platelet hyperreactivity in diabetes.
Volume: 137
Issue: 12
Pages: 1641-1651
Publication
First Author: Ishisaka M
Year: 2012
Journal: PLoS One
Title: Diacylglycerol kinase β knockout mice exhibit attention-deficit behavior and an abnormal response on methylphenidate-induced hyperactivity.
Volume: 7
Issue: 5
Pages: e37058
Publication  
First Author: Hozumi Y
Year: 2015
Journal: Brain Res
Title: Involvement of diacylglycerol kinase β in the spine formation at distal dendrites of striatal medium spiny neurons.
Volume: 1594
Pages: 36-45
Allele
Name: transgene insertion 1, Philippe Lesnik
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
Publication  
First Author: Nikouee A
Year: 2021
Journal: Front Cell Infect Microbiol
Title: Beclin-1-Dependent Autophagy Improves Outcomes of Pneumonia-Induced Sepsis.
Volume: 11
Pages: 706637
Genotype
Symbol: Bak1/Bak1 Bax/Bax
Background: involves: 129S1/Sv * 129S1/SvImJ * 129X1/SvJ * C57BL/6
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Dnmt1/Dnmt1<+> Tg(IghMyc)22Bri/? Tg(MMTVtTA)1Mam/?
Background: involves: 129S4/SvJae * C57BL/6
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Arpc3/Arpc3
Background: involves: C3H * C57BL * C57BL/6 * DBA
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Bax/Bax Ntrk1/Ntrk1
Background: involves: 129S1/Sv * 129X1/SvJ
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Arpc3/Arpc3
Background: Not Specified
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Bax/Bax<+> Nanos2/Nanos2
Background: involves: 129S1/Sv * 129X1/SvJ
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Bax/Bax Nanos2/Nanos2
Background: involves: 129S1/Sv * 129X1/SvJ
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Pik3cd/Pik3cd Tg(BCL2)36Wehi/?
Background: involves: 129S4/SvJae * C57BL/6JWehi * SJL/JWehi
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Bak1/Bak1 Bax/Bax
Background: involves: 129S1/Sv * 129X1/SvJ
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Bax/Bax Ntrk1/Ntrk1
Background: involves: 129S1/Sv * 129X1/SvJ
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Cd79b/Cd79b Tg(BCL2)22Wehi/? Tg(Rag2-Igb)1Mnz/?
Background: involves: 129S1/Sv * C57BL/6JWehi * SJL/JWehi
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Dgkb/Dgkb
Background: involves: C3H * C57BL/6 * DBA/2 * ICR
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Igh-J/Igh-J Igk-J/Igk-J Tg(BCL2)22Wehi/?
Background: involves: C57BL/6JWehi * SJL/JWehi
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Cbln1/Cbln1 Bax/Bax
Background: involves: 129S7/SvEvBrd * 129X1/SvJ
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Ebf1/Ebf1 Polr2a/Polr2a<+> Tg(BCL2)#Wehi/?
Background: involves: C57BL/6 * C57BL/6JWehi * SJL * SJL/JWehi
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Bax/Bax Del(18Pcdhg)1Xzw/Del(18Pcdhg)1Xzw
Background: involves: 129X1/SvJ
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Tg(BCL2)25Wehi/? Tg(Igkv3-5*-MYC)#Plbe/?
Background: involves: C57BL/6 * C57BL/6JWehi * SJL/JWehi
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Sppl2a/Sppl2a Tg(Vav-BCL2)69Jad/?
Background: involves: C57BL/6JAnu
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Bax/Bax Etv1/Etv1
Background: involves: 129S1/Sv * 129X1/SvJ
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Dgkb/Dgkb
Background: involves: C3H * C57BL/6 * C57BL/6N * DBA/2 * ICR
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Prkd2/Prkd2 Prkd3/Prkd3 Tg(BCL2)25Wehi/? Tg(Lck-cre)1Jtak/?
Background: involves: 129 * C57BL/6 * C57BL/6JWehi * SJL/JWehi
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Bak1/Bak1 Bax/Bax
Background: B6.129-Bax Bak1
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Bax/Bax Mcl1/Mcl1 Tg(Nes-cre)2472Pick/?
Background: involves: 129X1/SvJ * C57BL/6J * FVB/N
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Bax/Bax<+> Creb1/Creb1<+>
Background: involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Bax/Bax Creb1/Creb1<+>
Background: involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Bax/Bax Creb1/Creb1
Background: involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Bax/Bax Tg(Hlxb9-GFP)1Tmj/?
Background: involves: C57BL/6J * CBA
Zygosity: cx
Has Mutant Allele: true
Publication
First Author: Wright T
Year: 2024
Journal: Mol Cell
Title: Anti-apoptotic MCL-1 promotes long-chain fatty acid oxidation through interaction with ACSL1.
Volume: 84
Issue: 7
Pages: 1338-1353.e8
Publication
First Author: Kang SJ
Year: 2008
Journal: Immunity
Title: Regulation of hierarchical clustering and activation of innate immune cells by dendritic cells.
Volume: 29
Issue: 5
Pages: 819-33
Publication
First Author: Bonilla-Claudio M
Year: 2012
Journal: Development
Title: Bmp signaling regulates a dose-dependent transcriptional program to control facial skeletal development.
Volume: 139
Issue: 4
Pages: 709-19
Publication  
First Author: Ulmke PA
Year: 2021
Journal: Development
Title: Post-transcriptional regulation by the exosome complex is required for cell survival and forebrain development via repression of P53 signaling.
Volume: 148
Issue: 3
Publication
First Author: Yang P
Year: 2019
Journal: Nat Commun
Title: Tip60- and sirtuin 2-regulated MARCKS acetylation and phosphorylation are required for diabetic embryopathy.
Volume: 10
Issue: 1
Pages: 282
Publication
First Author: Spruce T
Year: 2010
Journal: Dev Cell
Title: An early developmental role for miRNAs in the maintenance of extraembryonic stem cells in the mouse embryo.
Volume: 19
Issue: 2
Pages: 207-19
Publication
First Author: Yao F
Year: 2023
Journal: Cell Death Dis
Title: Deletion of ARGLU1 causes global defects in alternative splicing in vivo and mouse cortical malformations primarily via apoptosis.
Volume: 14
Issue: 8
Pages: 543
Publication  
First Author: Phua YL
Year: 2015
Journal: Physiol Rep
Title: Renal stromal miRNAs are required for normal nephrogenesis and glomerular mesangial survival.
Volume: 3
Issue: 10
Publication
First Author: Yang SL
Year: 2015
Journal: Dev Biol
Title: MiR-302/367 regulate neural progenitor proliferation, differentiation timing, and survival in neurulation.
Volume: 408
Issue: 1
Pages: 140-50
Publication
First Author: Woodland RT
Year: 2008
Journal: Blood
Title: Multiple signaling pathways promote B lymphocyte stimulator dependent B-cell growth and survival.
Volume: 111
Issue: 2
Pages: 750-60
Publication
First Author: Ku B
Year: 2011
Journal: Cell Res
Title: Evidence that inhibition of BAX activation by BCL-2 involves its tight and preferential interaction with the BH3 domain of BAX.
Volume: 21
Issue: 4
Pages: 627-41
Protein
Organism: Mus musculus/domesticus
Length: 167  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 165  
Fragment?: false