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Search results 3601 to 3700 out of 8814 for Clock

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0.036s

Categories

Hits by Pathway

Hits by Category

Hits by Strain

Type Details Score
Genotype
Genotype
Symbol: Per1/Per1 Per2/Per2
Background: involves: 129S7/SvEvBrd * C57BL/6
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Per1/Per1 Per2/Per2
Background: involves: 129S4/SvJae
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Per1/Per1 Per3/Per3
Background: involves: 129S4/SvJae
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Per2/Per2 Per3/Per3
Background: involves: 129/Sv * 129S4/SvJae
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Per1/Per1 Per2/Per2
Background: involves: 129S7/SvEvBrd
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Cry2/Cry2 Per2/Per2
Background: B6J.Cg-Cry2 Per2
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Cry1/Cry1 Per2/Per2
Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Per1/Per1 Per2/Per2
Background: involves: 129S7/SvEvBrd * C57BL/6J
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Bmal1/Bmal1 Per2/Per2
Background: involves: 129 * C57BL/6J * CBA
Zygosity: cx
Has Mutant Allele: true
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Protein Domain
IPR009741 | EARLY_FLOWERING_4_dom
Type: Domain
Description: Protein EARLY FLOWERING 4 is a component of the central CCA1/LHY-TOC1 feedback loop in the circadian clock that promotes clock accuracy and is required for sustained rhythms in the absence of daily light/dark cycles [, ].This domain forms an α-helical homodimer in ELF4 proteins.
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Publication
18234727 | J:131837
First Author: Shifley ET
Year: 2008
Journal: Development
Title: Oscillatory lunatic fringe activity is crucial for segmentation of the anterior but not posterior skeleton.
Volume: 135
Issue: 5
Pages: 899-908
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Strain
MGI:3773630 | C57BL/6J-Tg(tetO-Clock)1Jt/J
Attribute String: mutant strain, transgenic, coisogenic
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Strain
MGI:5004018 | STOCK Tg(Clock-EGFP)JN7Gsat/Mmucd
Attribute String: mutant stock, transgenic
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Genotype
Genotype
Symbol: Lfng/Lfng
Background: involves: 129S6/SvEvTac * C57BL/6J
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Lfng/Lfng
Background: involves: 129 * C57BL/6J
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Lfng/Lfng<+>
Background: involves: 129 * C57BL/6J
Zygosity: ht
Has Mutant Allele: true
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Protein Coding Gene
MGI:2150037 | Mta1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:104871 | Ppp1cb
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
15767683 | J:97592
First Author: Eide EJ
Year: 2005
Journal: Mol Cell Biol
Title: Control of mammalian circadian rhythm by CKIepsilon-regulated proteasome-mediated PER2 degradation.
Volume: 25
Issue: 7
Pages: 2795-807
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Publication
19805627 | J:153811
First Author: Smith KD
Year: 2009
Journal: J Cell Biol
Title: Tim-Tipin dysfunction creates an indispensible reliance on the ATR-Chk1 pathway for continued DNA synthesis.
Volume: 187
Issue: 1
Pages: 15-23
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HT Experiment
E-GEOD-13062 | The effects of temporally restricted feeding on hepatic gene expression of Cry1, Cry2 double KO mice
Series Id: GSE13062
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
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HT Experiment
E-GEOD-35026 | Expression data in inguinal adipose tissue at different circadian times
Series Id: GSE35026
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
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Publication
25248974 | J:244271
 
First Author: Fujimuro T
Year: 2014
Journal: Sci Rep
Title: Hes7 3'UTR is required for somite segmentation function.
Volume: 4
Pages: 6462
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HT Experiment
E-GEOD-28622 | Expression data of mouse fetal liver during embryonic day 18 and 19
Series Id: GSE28622
Experiment Type: transcription profiling by array
Study Type: Baseline
Source: ArrayExpress
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Protein Coding Gene
MGI:1353425 | Opn4
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:98362 | Sox14
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1100865 | Rbm4
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
17462724 | J:122872
First Author: Siepka SM
Year: 2007
Journal: Cell
Title: Circadian mutant Overtime reveals F-box protein FBXL3 regulation of cryptochrome and period gene expression.
Volume: 129
Issue: 5
Pages: 1011-23
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Protein Domain
IPR022475 | UPF0273_KaiC-like
Type: Family
Description: Members of this family contain a single copy of the KaiC domain that occurs in two copies of the circadian clock protein kinase KaiC itself. Members occur primarily in archaea and in Thermotogales.
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Genotype
Genotype
Symbol: Clock/Clock<+> Usf1/Usf1<+>
Background: (BALB/cJ x C57BL/6J)F1
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Opn3/Opn3 Per2/Per2<+>
Background: involves: 129S6/SvEvTac * C57BL/6J * C57BL/6N * CBA
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Opn5/Opn5 Per2/Per2<+>
Background: involves: 129S6/SvEvTac
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Opn5/Opn5 Per2/Per2<+>
Background: involves: 129S4/SvJaeSor * 129S6/SvEvTac * C57BL/6N * FVB/N
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Per2/Per2<+> Zfhx3/Zfhx3<+>
Background: involves: 129S6/SvEvTac * BALB/cOlaHsd * C3H/HeH * C57BL/6J
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Bmal1/Bmal1 Per2/Per2 Tg(Col2a1-cre)1Asz/?
Background: involves: 129 * C57BL/6J * CBA
Zygosity: cn
Has Mutant Allele: true
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HT Experiment
E-MTAB-1576 | Transcription profiling by array of mouse colon mucosal tissues isolated every 4 hours within a 24-hour period to study genes involved in circadian regulation
 
Experiment Type: transcription profiling by array
Study Type: Baseline
Source: ArrayExpress
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HT Experiment
E-MTAB-7496 | RNA-seq of neuronal SOX2-ablated murine suprachiasmatic nuclei against wild-type littermate controls
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: ArrayExpress
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HT Experiment
GSE215138 | Fetal origin of sex-bias brain aging [RNA-seq]
 
Experiment Type: RNA-Seq
Study Type: Baseline
Source: GEO
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HT Experiment
GSE214514 | Microglial gene expression in Bmal1 cKO and WT mice
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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HT Experiment
GSE240710 | Novel Roles for the Transcriptional Repressor E4BP4 in Both Cardiac Physiology and Pathophysiology [4 mouse lines]
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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HT Experiment
GSE243522 | More than the clock: distinct regulation of muscle function and metabolism by PER2 and RORalpha
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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Protein Domain
IPR014774 | KaiC-like_dom
Type: Domain
Description: This entry represents a domain found in KaiC, which is a core component of the KaiBC clock protein complex that constitutes the main circadian regulator in cyanobacteria []. The circadian clock protein KaiC, is encoded in the kaiABC operon that controls circadian rhythms and may be universal in Cyanobacteria. Each member contains two copies of this domain, which is alsofound in other proteins. KaiC performs autophosphorylation and acts as its own transcriptional repressor.Proteins containing this domain also include some eukrayotic proteins.
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Publication
17141802 | J:120297
First Author: Gotter AL
Year: 2007
Journal: J Mol Biol
Title: Mammalian TIMELESS and Tipin are evolutionarily conserved replication fork-associated factors.
Volume: 366
Issue: 1
Pages: 36-52
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Publication
27135601 | J:240217
First Author: Xu Y
Year: 2016
Journal: PLoS Genet
Title: Long-Range Chromosome Interactions Mediated by Cohesin Shape Circadian Gene Expression.
Volume: 12
Issue: 5
Pages: e1005992
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HT Experiment
E-GEOD-43073 | IMPACT OF CARDIOMYOCYTE-SPECIFIC BMAL1 DELETION ON MYOCARDIAL GENE EXPRESSION, METABOLISM, AND CONTRACTILE FUNCTION
Series Id: GSE43073
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
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HT Experiment
E-GEOD-14006 | Expression profiling of Bmal mutant dorsal skin at telogen of hair follicle cycling
Series Id: GSE14006
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
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Publication
28802827 | J:271694
 
First Author: Adachi Y
Year: 2017
Journal: Arch Biochem Biophys
Title: The novel heme-dependent inducible protein, SRRD regulates heme biosynthesis and circadian rhythms.
Volume: 631
Pages: 19-29
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Protein Coding Gene
MGI:104754 | Sik1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:103016 | Ppp1ca
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:104872 | Ppp1cc
Type: protein_coding_gene
Organism: mouse, laboratory
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HT Experiment
E-GEOD-75523 | Circadian mRNA expression in skeletal muscle of young and aged mice
Series Id: GSE75523
Experiment Type: transcription profiling by array
Study Type: Baseline
Source: ArrayExpress
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HT Experiment
E-MTAB-8402 | Antibody-independent ChIP-sequencing and liver-targeted deletion redefine REVERBalpha repressor function - RNA-seq
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: ArrayExpress
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HT Experiment
E-MTAB-12877 | Mechanical loading and hyperosmolarity as a daily resetting cue for skeletal circadian clocks
 
Experiment Type: RNA-Seq
Study Type: Baseline
Source: ArrayExpress
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HT Experiment
E-GEOD-37387 | Transcript levels in mouse liver
Series Id: GSE37387
Experiment Type: transcription profiling by array
Study Type: Baseline
Source: ArrayExpress
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HT Experiment
E-GEOD-69853 | Genome-wide screen reveals rhythmic regulation of genes involved in odor processing in the olfactory epithelium
Series Id: GSE69853
Experiment Type: transcription profiling by array
Study Type: Baseline
Source: ArrayExpress
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HT Experiment
GSE17739 | Circadian gene profiling in the distal nephron and collecting ducts
 
Experiment Type: transcription profiling by array
Study Type: Baseline
Source: GEO
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HT Experiment
GSE232957 | Muscle-specific rescue of Bmal1 impacts survival and health span of the Bmal1-KO mouse
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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HT Experiment
E-GEOD-54650 | A circadian gene expression atlas in mammals assayed by microarray
Series Id: GSE54650
Experiment Type: transcription profiling by array
Study Type: Baseline
Source: ArrayExpress
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HT Experiment
E-MTAB-7151 | Microarray analysis of mouse cerebral cortex from brain-specific Bmal1 knockout and Per1;Per2 double mutant mice at 2 timepoints
 
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
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HT Experiment
GSE151350 | Diurnal gene expression in the retina of a mouse model of diabetic retinopathy
 
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: GEO
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HT Experiment
GSE191264 | Parathyroid tissue transcriptome over 24h of PTHcre;Bmal1 flox/flox mice and of Bmal1 flox/flox mice
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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HT Experiment
E-GEOD-54651 | A circadian gene expression atlas in mammals assayed by RNA-seq
Series Id: GSE54651
Experiment Type: RNA-Seq
Study Type: Baseline
Source: ArrayExpress
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Protein Domain
IPR039928 | LNK
Type: Family
Description: The LNK family consists of light and clock regulated morning genes from plants. These control both the pace of circadian rhythms and the photoperiodic regulation of flowering time by promoting the expression of a subset of clock and flowering time genes in the afternoon []. The LCL domain of clock-related factor REVEILLE8 recruits LNKs to target promoters, while its MYB domain provides DNA binding specificity. In turn, LNKs interact with RNA Polymerase II and the transcript elongation FACT complex, resulting in rhythmic changes of gene expression [].
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Protein Domain
IPR023527 | Kinase_SasA
Type: Family
Description: This entry represents the adaptive-response sensory-kinase sasA family which may be involved in signal transduction. This family of proteins participate in the kaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria, via its interaction with kaiC []. The kaiABC complex has a core comprising a kaiC homohexamer, a kaiB dimer and two kaiA dimers. The adaptive-response sensory-kinase sasA is required for robustness of the circadian rhythm of gene expression and is involved in clock outputs. The proteins contain a histidine kinase domain.
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Protein Coding Gene
MGI:2135679 | Hes7
Type: protein_coding_gene
Organism: mouse, laboratory
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HT Experiment
E-GEOD-36873 | Nascent-Seq Reveals Novel Features of Mouse Circadian Transcriptional Regulation [StrandSpe_NascentSeq]
Series Id: GSE36873
Experiment Type: RNA-Seq
Study Type: Baseline
Source: ArrayExpress
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HT Experiment
E-GEOD-36871 | Nascent-Seq Reveals Novel Features of Mouse Circadian Transcriptional Regulation [RNA-Seq]
Series Id: GSE36871
Experiment Type: RNA-Seq
Study Type: Baseline
Source: ArrayExpress
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HT Experiment
E-GEOD-36872 | Nascent-Seq Reveals Novel Features of Mouse Circadian Transcriptional Regulation [Nascent-Seq]
Series Id: GSE36872
Experiment Type: RNA-Seq
Study Type: Baseline
Source: ArrayExpress
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Genotype
Genotype
Symbol: Per1/Per1 Per2/Per2 Tg(Col1a1-cre)1Kry/?
Background: involves: 129S7/SvEvBrd * FVB
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Opn1sw/Opn1sw Per2/Per2<+>
Background: involves: 129S6/SvEvTac
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Opn5/Opn5 Per2/Per2<+>
Background: involves: 129S4/SvJaeSor * 129S6/SvEvTac * C57BL/6N * FVB/N
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Clock/Clock<+> Per2/Per2<+> Usf1/?
Background: involves: 129S6/SvEvTac * BALB/cJ * C57BL/6J
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Alb/Alb<+> Per2/Per2<+> Smg6/Smg6
Background: involves: 129S2/SvPas * 129S6/SvEvTac * C57BL/6J
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Bmal1/Bmal1 Per2/Per2<+> Tg(Col6a1-cre)1Gkl/?
Background: involves: 129S4/SvJae * 129S6/SvEvTac * C57BL/6J * CBA * DBA/1
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(Scg2-tTA)1Jt/? Tg(tetO-Clock)1Jt/?
Background: involves: C57BL/6J * CD-1
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Lfng/Lfng
Background: involves: 129 * C57BL/6J
Zygosity: ht
Has Mutant Allele: true
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Publication
35172136 | J:324794
First Author: Hong H
Year: 2022
Journal: Cell Rep
Title: Postnatal regulation of B-1a cell development and survival by the CIC-PER2-BHLHE41 axis.
Volume: 38
Issue: 7
Pages: 110386
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Publication
21857934 | J:176505
First Author: Wang JL
Year: 2011
Journal: PLoS One
Title: Calcium prevents tumorigenesis in a mouse model of colorectal cancer.
Volume: 6
Issue: 8
Pages: e22566
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Protein
Q9WTJ8
Organism: Mus musculus/domesticus
Length: 334  
Fragment?: false
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Publication
15060175 | -
First Author: Castet A
Year: 2004
Journal: Nucleic Acids Res
Title: Multiple domains of the Receptor-Interacting Protein 140 contribute to transcription inhibition.
Volume: 32
Issue: 6
Pages: 1957-66
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Publication
14736873 | J:114142
First Author: Christian M
Year: 2004
Journal: J Biol Chem
Title: Characterization of four autonomous repression domains in the corepressor receptor interacting protein 140.
Volume: 279
Issue: 15
Pages: 15645-51
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Protein
Q9WV03
Organism: Mus musculus/domesticus
Length: 339  
Fragment?: false
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Protein
Q3TQ03
Organism: Mus musculus/domesticus
Length: 375  
Fragment?: false
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Protein
Q8R0W1
Organism: Mus musculus/domesticus
Length: 432  
Fragment?: false
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Protein
A2RTE4
Organism: Mus musculus/domesticus
Length: 375  
Fragment?: false
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Protein
A0A087WRF0
Organism: Mus musculus/domesticus
Length: 82  
Fragment?: false
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Protein
F6U6T6
Organism: Mus musculus/domesticus
Length: 115  
Fragment?: true
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Protein
A0A087WPE5
Organism: Mus musculus/domesticus
Length: 81  
Fragment?: false
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Protein
A0A087WRZ3
Organism: Mus musculus/domesticus
Length: 79  
Fragment?: true
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Protein
H3BJP8
Organism: Mus musculus/domesticus
Length: 185  
Fragment?: true
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Protein
A0A087WNZ2
Organism: Mus musculus/domesticus
Length: 131  
Fragment?: true
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Protein
A0A087WQ97
Organism: Mus musculus/domesticus
Length: 60  
Fragment?: false
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Protein
Q05AF0
Organism: Mus musculus/domesticus
Length: 267  
Fragment?: false
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Protein
A0A158SIT3
Organism: Mus musculus/domesticus
Length: 339  
Fragment?: false
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Protein
H3BKT8
Organism: Mus musculus/domesticus
Length: 55  
Fragment?: true
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Protein
E0CYK0
Organism: Mus musculus/domesticus
Length: 154  
Fragment?: true
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Protein
Z4YJJ0
Organism: Mus musculus/domesticus
Length: 411  
Fragment?: false
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Publication
32703943 | -
First Author: Lee YR
Year: 2020
Journal: Nat Commun
Title: Mutations in FAM50A suggest that Armfield XLID syndrome is a spliceosomopathy.
Volume: 11
Issue: 1
Pages: 3698
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Publication
19591933 | -
First Author: Mishra A
Year: 2009
Journal: Neurobiol Dis
Title: UBE3A/E6-AP regulates cell proliferation by promoting proteasomal degradation of p27.
Volume: 36
Issue: 1
Pages: 26-34
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Publication
21612333 | -
First Author: Wang X
Year: 2011
Journal: Ann Med
Title: MAGED1: molecular insights and clinical implications.
Volume: 43
Issue: 5
Pages: 347-55
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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