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Search results 3701 to 3800 out of 4449 for Apc

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Type Details Score
Publication
First Author: Conner JM
Year: 2021
Journal: Science
Title: Modulation of tactile feedback for the execution of dexterous movement.
Volume: 374
Issue: 6565
Pages: 316-323
Publication
First Author: Schreck MR
Year: 2022
Journal: Cell Rep
Title: State-dependent olfactory processing in freely behaving mice.
Volume: 38
Issue: 9
Pages: 110450
Publication
First Author: Bezuhly M
Year: 2009
Journal: Blood
Title: Role of activated protein C and its receptor in inhibition of tumor metastasis.
Volume: 113
Issue: 14
Pages: 3371-4
Publication
First Author: Saavedra-Peña RDM
Year: 2023
Journal: Cell Rep
Title: Estradiol cycling drives female obesogenic adipocyte hyperplasia.
Volume: 42
Issue: 4
Pages: 112390
Publication
First Author: Gao Z
Year: 2020
Journal: Nat Metab
Title: Age-associated telomere attrition in adipocyte progenitors predisposes to metabolic disease.
Volume: 2
Issue: 12
Pages: 1482-1497
Publication
First Author: Liang J
Year: 2016
Journal: Cell Rep
Title: Inflammatory Th1 and Th17 in the Intestine Are Each Driven by Functionally Specialized Dendritic Cells with Distinct Requirements for MyD88.
Volume: 17
Issue: 5
Pages: 1330-1343
Publication
First Author: Ledvin L
Year: 2023
Journal: Dev Cell
Title: The anaphase-promoting complex controls a ubiquitination-phosphoprotein axis in chromatin during neurodevelopment.
Volume: 58
Issue: 23
Pages: 2666-2683.e9
Publication
First Author: Cheng F
Year: 2014
Journal: Mol Immunol
Title: Divergent roles of histone deacetylase 6 (HDAC6) and histone deacetylase 11 (HDAC11) on the transcriptional regulation of IL10 in antigen presenting cells.
Volume: 60
Issue: 1
Pages: 44-53
Publication
First Author: Large AM
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: Differential inhibition of pyramidal cells and inhibitory interneurons along the rostrocaudal axis of anterior piriform cortex.
Volume: 115
Issue: 34
Pages: E8067-E8076
Publication
First Author: Surman DR
Year: 2000
Journal: J Immunol
Title: Cutting edge: CD4+ T cell control of CD8+ T cell reactivity to a model tumor antigen.
Volume: 164
Issue: 2
Pages: 562-5
Publication
First Author: Toubai T
Year: 2013
Journal: Blood
Title: Host-derived CD8+ dendritic cells are required for induction of optimal graft-versus-tumor responses after experimental allogeneic bone marrow transplantation.
Volume: 121
Issue: 20
Pages: 4231-41
Publication
First Author: Wetzel SA
Year: 2002
Journal: J Immunol
Title: Live-cell dynamics and the role of costimulation in immunological synapse formation.
Volume: 169
Issue: 11
Pages: 6092-101
Publication
First Author: Varshney R
Year: 2023
Journal: iScience
Title: Neonatal intake of Omega-3 fatty acids enhances lipid oxidation in adipocyte precursors.
Volume: 26
Issue: 1
Pages: 105750
Publication  
First Author: Liu J
Year: 2022
Journal: Development
Title: Molecular divergence of mammalian astrocyte progenitor cells at early gliogenesis.
Volume: 149
Issue: 5
Publication  
First Author: Zoungrana LI
Year: 2023
Journal: Biochem Biophys Rep
Title: Activated protein C signaling mediates neuroinflammation in seizure induced by pilocarpine.
Volume: 35
Pages: 101550
Publication
First Author: Gaudet S
Year: 2000
Journal: Proc Natl Acad Sci U S A
Title: Characterization of PDZ-binding kinase, a mitotic kinase.
Volume: 97
Issue: 10
Pages: 5167-72
Publication
First Author: Yang Y
Year: 2007
Journal: J Immunol
Title: Characterization of B7S3 as a novel negative regulator of T cells.
Volume: 178
Issue: 6
Pages: 3661-7
Publication
First Author: Fallarino F
Year: 2002
Journal: Int Immunol
Title: Functional expression of indoleamine 2,3-dioxygenase by murine CD8 alpha(+) dendritic cells.
Volume: 14
Issue: 1
Pages: 65-8
Publication
First Author: Reimann JD
Year: 2001
Journal: Cell
Title: Emi1 is a mitotic regulator that interacts with Cdc20 and inhibits the anaphase promoting complex.
Volume: 105
Issue: 5
Pages: 645-55
Publication  
First Author: Williams C
Year: 1999
Journal: Ann N Y Acad Sci
Title: The role of COX-2 in intestinal cancer.
Volume: 889
Pages: 72-83
Publication
First Author: Mizuochi T
Year: 1990
Journal: J Immunol
Title: A selective signaling defect in helper T cells induced by antigen-presenting cells from mice with murine acquired immunodeficiency syndrome.
Volume: 144
Issue: 1
Pages: 313-6
Publication
First Author: Saito N
Year: 1985
Journal: Exp Clin Immunogenet
Title: Low responsiveness to MLM bacilli associated with an impaired macrophage function in CBA/J mice.
Volume: 2
Issue: 1
Pages: 24-35
Publication
First Author: Haruna H
Year: 1995
Journal: Eur J Immunol
Title: Abnormalities of B cells and dendritic cells in SAMP1 mice.
Volume: 25
Issue: 5
Pages: 1319-25
Publication
First Author: Shimizu J
Year: 1995
Journal: J Immunol
Title: Relationship between beta cell injury and antigen presentation in NOD mice.
Volume: 155
Issue: 8
Pages: 4095-9
Publication
First Author: Kristensen NM
Year: 1996
Journal: Int Immunol
Title: Induction of T cell responses to the invariant chain derived peptide CLIP in mice immunized with the group 1 allergen of house dust mite.
Volume: 8
Issue: 7
Pages: 1091-8
Publication
First Author: Prolla TA
Year: 1996
Journal: Semin Cancer Biol
Title: DNA mismatch repair deficient mice in cancer research.
Volume: 7
Issue: 5
Pages: 241-7
Publication
First Author: Armstrong TD
Year: 1998
Journal: J Immunol
Title: MHC class II-transfected tumor cells directly present antigen to tumor-specific CD4+ T lymphocytes.
Volume: 160
Issue: 2
Pages: 661-6
Publication
First Author: Haigis KM
Year: 2002
Journal: Proc Natl Acad Sci U S A
Title: Intestinal adenomas can develop with a stable karyotype and stable microsatellites.
Volume: 99
Issue: 13
Pages: 8927-31
Publication
First Author: Cannons JL
Year: 2002
Journal: J Immunol
Title: Cutting edge: profound defect in T cell responses in TNF receptor-associated factor 2 dominant negative mice.
Volume: 169
Issue: 6
Pages: 2828-31
Publication
First Author: Dashwood RH
Year: 2003
Journal: J Biochem Mol Biol
Title: Use of transgenic and mutant animal models in the study of heterocyclic amine-induced mutagenesis and carcinogenesis.
Volume: 36
Issue: 1
Pages: 35-42
Publication
First Author: Boisvert J
Year: 2004
Journal: J Immunol
Title: Immunological synapse formation licenses CD40-CD40L accumulations at T-APC contact sites.
Volume: 173
Issue: 6
Pages: 3647-52
Publication
First Author: Hursting SD
Year: 2005
Journal: Mutat Res
Title: The utility of genetically altered mouse models for nutrition and cancer chemoprevention research.
Volume: 576
Issue: 1-2
Pages: 80-92
Publication
First Author: Sköld M
Year: 2005
Journal: J Immunol
Title: Interplay of cytokines and microbial signals in regulation of CD1d expression and NKT cell activation.
Volume: 175
Issue: 6
Pages: 3584-93
Publication
First Author: Hwang I
Year: 2000
Journal: J Exp Med
Title: T cells can use either T cell receptor or CD28 receptors to absorb and internalize cell surface molecules derived from antigen-presenting cells.
Volume: 191
Issue: 7
Pages: 1137-48
Publication
First Author: Bose M
Year: 2007
Journal: J Agric Food Chem
Title: Inhibition of tumorigenesis in ApcMin/+ mice by a combination of (-)-epigallocatechin-3-gallate and fish oil.
Volume: 55
Issue: 19
Pages: 7695-700
Publication
First Author: Tskvitaria-Fuller I
Year: 2006
Journal: J Immunol
Title: Specific patterns of Cdc42 activity are related to distinct elements of T cell polarization.
Volume: 177
Issue: 3
Pages: 1708-20
Publication
First Author: Hendriksen J
Year: 2008
Journal: J Cell Sci
Title: Plasma membrane recruitment of dephosphorylated beta-catenin upon activation of the Wnt pathway.
Volume: 121
Issue: 11
Pages: 1793-802
Publication
First Author: Anderson AC
Year: 2008
Journal: J Immunol
Title: Cutting edge: the Idd3 genetic interval determines regulatory T cell function through CD11b+CD11c- APC.
Volume: 181
Issue: 11
Pages: 7449-52
Publication
First Author: Taketo MM
Year: 2009
Journal: Gastroenterology
Title: Mouse models of colon cancer.
Volume: 136
Issue: 3
Pages: 780-98
Publication
First Author: Harmey D
Year: 2009
Journal: J Biol Chem
Title: The anaphase promoting complex induces substrate degradation during neuronal differentiation.
Volume: 284
Issue: 7
Pages: 4317-23
Publication
First Author: Homer H
Year: 2009
Journal: Science
Title: A spindle assembly checkpoint protein functions in prophase I arrest and prometaphase progression.
Volume: 326
Issue: 5955
Pages: 991-4
Publication
First Author: Verhagen MP
Year: 2024
Journal: Nat Genet
Title: Non-stem cell lineages as an alternative origin of intestinal tumorigenesis in the context of inflammation.
Volume: 56
Issue: 7
Pages: 1456-1467
Publication
First Author: Pereira CS
Year: 2016
Journal: Eur J Immunol
Title: Globotriaosylceramide inhibits iNKT-cell activation in a CD1d-dependent manner.
Volume: 46
Issue: 1
Pages: 147-53
Publication
First Author: Esterházy D
Year: 2016
Journal: Nat Immunol
Title: Classical dendritic cells are required for dietary antigen-mediated induction of peripheral T(reg) cells and tolerance.
Volume: 17
Issue: 5
Pages: 545-55
Publication  
First Author: Zhou C
Year: 2019
Journal: J Cell Sci
Title: First meiotic anaphase requires Cep55-dependent inhibitory cyclin-dependent kinase 1 phosphorylation.
Volume: 132
Issue: 18
Publication
First Author: Flanagan DJ
Year: 2019
Journal: Cancer Res
Title: Wnt Signaling in Cancer: Not a Binary ON:OFF Switch.
Volume: 79
Issue: 23
Pages: 5901-5906
Publication
First Author: Pickering KA
Year: 2021
Journal: Nat Commun
Title: A RAC-GEF network critical for early intestinal tumourigenesis.
Volume: 12
Issue: 1
Pages: 56
Publication  
First Author: Hellmeier J
Year: 2021
Journal: Proc Natl Acad Sci U S A
Title: DNA origami demonstrate the unique stimulatory power of single pMHCs as T cell antigens.
Volume: 118
Issue: 4
Publication
First Author: Giroux V
Year: 2018
Journal: Stem Cell Reports
Title: Mouse Intestinal Krt15+ Crypt Cells Are Radio-Resistant and Tumor Initiating.
Volume: 10
Issue: 6
Pages: 1947-1958
Publication
First Author: Allen BM
Year: 2020
Journal: Nat Med
Title: Systemic dysfunction and plasticity of the immune macroenvironment in cancer models.
Volume: 26
Issue: 7
Pages: 1125-1134
Publication
First Author: Cho YH
Year: 2016
Journal: Oncotarget
Title: KY1022, a small molecule destabilizing Ras via targeting the Wnt/β-catenin pathway, inhibits development of metastatic colorectal cancer.
Volume: 7
Issue: 49
Pages: 81727-81740
Publication
First Author: Heino S
Year: 2021
Journal: Sci Adv
Title: Lef1 restricts ectopic crypt formation and tumor cell growth in intestinal adenomas.
Volume: 7
Issue: 47
Pages: eabj0512
Publication
First Author: Chinnappa K
Year: 2022
Journal: Sci Adv
Title: Secondary loss of miR-3607 reduced cortical progenitor amplification during rodent evolution.
Volume: 8
Issue: 2
Pages: eabj4010
Publication  
First Author: Efimova N
Year: 2020
Journal: J Cell Biol
Title: Branched actin networks are assembled on microtubules by adenomatous polyposis coli for targeted membrane protrusion.
Volume: 219
Issue: 9
Publication
First Author: Bala P
Year: 2023
Journal: Sci Adv
Title: Aberrant cell state plasticity mediated by developmental reprogramming precedes colorectal cancer initiation.
Volume: 9
Issue: 13
Pages: eadf0927
Publication
First Author: Roper J
Year: 2017
Journal: Nat Biotechnol
Title: In vivo genome editing and organoid transplantation models of colorectal cancer and metastasis.
Volume: 35
Issue: 6
Pages: 569-576
Protein
Organism: Mus musculus/domesticus
Length: 84  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 2274  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 2303  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 2274  
Fragment?: false
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Pseudogene
Type: pseudogene
Organism: mouse, laboratory
Publication
First Author: Mateus Gonçalves L
Year: 2020
Journal: Diabetologia
Title: Islet pericytes convert into profibrotic myofibroblasts in a mouse model of islet vascular fibrosis.
Volume: 63
Issue: 8
Pages: 1564-1575
Publication
First Author: Palazuelos J
Year: 2014
Journal: J Neurosci
Title: TACE/ADAM17 is essential for oligodendrocyte development and CNS myelination.
Volume: 34
Issue: 36
Pages: 11884-96
Publication
First Author: Solga AC
Year: 2014
Journal: Oncogene
Title: NG2-cells are not the cell of origin for murine neurofibromatosis-1 (Nf1) optic glioma.
Volume: 33
Issue: 3
Pages: 289-99
Publication  
First Author: Minocha S
Year: 2017
Journal: Sci Rep
Title: Nkx2.1 regulates the generation of telencephalic astrocytes during embryonic development.
Volume: 7
Pages: 43093
Publication
First Author: Zhu X
Year: 2008
Journal: Development
Title: NG2 cells generate both oligodendrocytes and gray matter astrocytes.
Volume: 135
Issue: 1
Pages: 145-57
Publication
First Author: Wei Q
Year: 2020
Journal: Dev Cell
Title: Snai2 Maintains Bone Marrow Niche Cells by Repressing Osteopontin Expression.
Volume: 53
Issue: 5
Pages: 503-513.e5
Publication
First Author: Urrutia AA
Year: 2016
Journal: Blood
Title: Prolyl-4-hydroxylase 2 and 3 coregulate murine erythropoietin in brain pericytes.
Volume: 128
Issue: 21
Pages: 2550-2560
Publication    
First Author: Zhou L
Year: 2020
Journal: Elife
Title: Gab1 mediates PDGF signaling and is essential to oligodendrocyte differentiation and CNS myelination.
Volume: 9
Publication
First Author: Palazuelos J
Year: 2014
Journal: J Neurosci
Title: TGFβ signaling regulates the timing of CNS myelination by modulating oligodendrocyte progenitor cell cycle exit through SMAD3/4/FoxO1/Sp1.
Volume: 34
Issue: 23
Pages: 7917-30
Publication    
First Author: Minocha S
Year: 2015
Journal: Elife
Title: NG2 glia are required for vessel network formation during embryonic development.
Volume: 4
Publication
First Author: Grutzendler J
Year: 2014
Journal: Sci Transl Med
Title: Angiophagy prevents early embolus washout but recanalizes microvessels through embolus extravasation.
Volume: 6
Issue: 226
Pages: 226ra31
Publication
First Author: Sánchez-de la Torre A
Year: 2022
Journal: Cell Death Dis
Title: Cannabinoid CB(1) receptor gene inactivation in oligodendrocyte precursors disrupts oligodendrogenesis and myelination in mice.
Volume: 13
Issue: 7
Pages: 585
Publication
First Author: Sherafat A
Year: 2021
Journal: Nat Commun
Title: Microglial neuropilin-1 promotes oligodendrocyte expansion during development and remyelination by trans-activating platelet-derived growth factor receptor.
Volume: 12
Issue: 1
Pages: 2265
Publication
First Author: Komitova M
Year: 2011
Journal: Glia
Title: NG2 cells are not a major source of reactive astrocytes after neocortical stab wound injury.
Volume: 59
Issue: 5
Pages: 800-9
Publication
First Author: Damisah EC
Year: 2017
Journal: Nat Neurosci
Title: A fluoro-Nissl dye identifies pericytes as distinct vascular mural cells during in vivo brain imaging.
Volume: 20
Issue: 7
Pages: 1023-1032
Publication
First Author: Jung B
Year: 2018
Journal: J Cereb Blood Flow Metab
Title: Visualization of vascular mural cells in developing brain using genetically labeled transgenic reporter mice.
Volume: 38
Issue: 3
Pages: 456-468
Publication  
First Author: Kovacs-Oller T
Year: 2020
Journal: Cell Discov
Title: The pericyte connectome: spatial precision of neurovascular coupling is driven by selective connectivity maps of pericytes and endothelial cells and is disrupted in diabetes.
Volume: 6
Pages: 39
Publication
First Author: Alarcon-Martinez L
Year: 2020
Journal: Nature
Title: Interpericyte tunnelling nanotubes regulate neurovascular coupling.
Volume: 585
Issue: 7823
Pages: 91-95
Publication  
First Author: Romanò N
Year: 2023
Journal: JCI Insight
Title: Median eminence blood flow influences food intake by regulating ghrelin access to the metabolic brain.
Volume: 8
Issue: 3
Publication
First Author: Tong L
Year: 2023
Journal: iScience
Title: Single cell in vivo optogenetic stimulation by two-photon excitation fluorescence transfer.
Volume: 26
Issue: 10
Pages: 107857
Publication
First Author: Armulik A
Year: 2011
Journal: Dev Cell
Title: Pericytes: developmental, physiological, and pathological perspectives, problems, and promises.
Volume: 21
Issue: 2
Pages: 193-215
Publication
First Author: Khan JA
Year: 2016
Journal: Science
Title: Fetal liver hematopoietic stem cell niches associate with portal vessels.
Volume: 351
Issue: 6269
Pages: 176-80
Publication
First Author: Hanoun M
Year: 2019
Journal: Stem Cell Reports
Title: Nestin+NG2+ Cells Form a Reserve Stem Cell Population in the Mouse Prostate.
Volume: 12
Issue: 6
Pages: 1201-1211
Protein
Organism: Mus musculus/domesticus
Length: 577  
Fragment?: true
Publication
First Author: Niegemann E
Year: 1993
Journal: Arch Microbiol
Title: Molecular organization of the Escherichia coli gab cluster: nucleotide sequence of the structural genes gabD and gabP and expression of the GABA permease gene.
Volume: 160
Issue: 6
Pages: 454-60
Publication
First Author: Luo W
Year: 2004
Journal: Neurosignals
Title: Axin: a master scaffold for multiple signaling pathways.
Volume: 13
Issue: 3
Pages: 99-113
Protein Domain
Type: Family
Description: T cell-dependent immune processes require cell-surface interactions thatmediate the initiation, modulation and the ultimate course of the response.The specificity of T cell recognition is determined by the engagement of theT cell receptor (TCR) on T cells with cognate peptide-MHC complexes presented by antigen presenting cells (APCs). Additional signals arerequired to sustain and enhance T cell activity, the most important of whichis provided by the engagement of CD28 on T cells with its ligands B7-1(CD80) and B7-2 (CD86). By contrast, the interaction of B7 isoformswith cytotoxic T lymphocyte-associated molecule-4 CTLA-4, a CD28 homologue receptor on T cells (31% identity), provides inhibitory signals requiredfor down-regulation of the response, while it may also prevent T cell activation by weak TCR signals[, , , , ].Unlike CD28, which is not expressed on resting T cells, CTLA-4 is not detected on the cell surface until 24 hours after activation. In fact, Tcell activation leads to both increased CTLA4 gene expression andtrafficking of CTLA4 protein to the cell surface. In addition, CTLA-4exhibits an affinity for the B7 isoforms that is 10 to 100 times that forCD28. Covalent dimerisation of CTLA4 is required for its high bindingavidity, but each monomeric subunit also contains a binding site for CD80and CD86. It is likely that CTLA-4 directly competes with CD28 for bindingB7 and also directs the assembly of inhibitory signalling complexes thatlead to quiescence or anergy. Thus the balance between the opposing signals elicited by CD28 and CTLA-4 is central to the regulation of T cellresponsiveness and homeostasis. One mechanism by which CTLA-4 may performthis function is by regulating cell-cycle progression; by contrast with CD28, which down-regulates the cell-cycle inhibitor p27kip1, CTLA-4 prevents this degradation[, , ].Sequence comparison between human CTLA-4 and CD28 proteins suggests they arehomologous, with the highest of degree of similarity being in the juxta-membrane and cytoplasmic regions. In addition, the cytoplasmic domainsof human and murine CTLA-4 are identical, suggesting that this region hasimportant functional properties [].Typically, activation of T cells by TCR-engaging peptide-MHC is dramatically enhanced by interaction of the CD28 co-stimulatory receptor with its ligands CD80 (B7-1) and CD86 (B7-2) on the APC surface. Interestingly, CTLA-4 is transported from intracellular stores toward the region of the cell surface receiving activation signals. This suggests that binding of CD28 to its ligand may occur primarily at the centre of the mature immunological synapse, and that CTLA-4 may be transported to this site under certain circumstancesto block or reverse this effect.
Protein
Organism: Mus musculus/domesticus
Length: 837  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 833  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 224  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 838  
Fragment?: true
Publication
First Author: Chen C
Year: 1994
Journal: J Immunol
Title: Molecular cloning and expression of early T cell costimulatory molecule-1 and its characterization as B7-2 molecule.
Volume: 152
Issue: 10
Pages: 4929-36
Publication
First Author: Draber P
Year: 2011
Journal: Mol Cell Biol
Title: SCIMP, a transmembrane adaptor protein involved in major histocompatibility complex class II signaling.
Volume: 31
Issue: 22
Pages: 4550-62