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Search results 3701 to 3800 out of 8321 for Src

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Type Details Score
Genotype
Symbol: Lyn/Lyn<+>
Background: C57BL/6J-Lyn
Zygosity: ht
Has Mutant Allele: true
Publication
First Author: Shih NY
Year: 1999
Journal: Science
Title: Congenital nephrotic syndrome in mice lacking CD2-associated protein.
Volume: 286
Issue: 5438
Pages: 312-5
Strain
Attribute String: targeted mutation, congenic
Publication
First Author: Peters I
Year: 2006
Journal: J Am Soc Nephrol
Title: IGF-binding protein-3 modulates TGF-beta/BMP-signaling in glomerular podocytes.
Volume: 17
Issue: 6
Pages: 1644-56
Publication
First Author: Grunkemeyer JA
Year: 2005
Journal: J Biol Chem
Title: CD2-associated protein (CD2AP) expression in podocytes rescues lethality of CD2AP deficiency.
Volume: 280
Issue: 33
Pages: 29677-81
Publication
First Author: Schiffer M
Year: 2004
Journal: J Biol Chem
Title: A novel role for the adaptor molecule CD2-associated protein in transforming growth factor-beta-induced apoptosis.
Volume: 279
Issue: 35
Pages: 37004-12
Publication
First Author: Kim JM
Year: 2003
Journal: Science
Title: CD2-associated protein haploinsufficiency is linked to glomerular disease susceptibility.
Volume: 300
Issue: 5623
Pages: 1298-300
Publication
First Author: Russo LM
Year: 2013
Journal: FEBS Lett
Title: Albuminuria associated with CD2AP knockout mice is primarily due to dysfunction of the renal degradation pathway processing of filtered albumin.
Volume: 587
Issue: 22
Pages: 3738-41
Publication
First Author: Tsuji K
Year: 2017
Journal: Sci Rep
Title: Re-characterization of the Glomerulopathy in CD2AP Deficient Mice by High-Resolution Helium Ion Scanning Microscopy.
Volume: 7
Issue: 1
Pages: 8321
Publication
First Author: Schiffer M
Year: 2002
Journal: J Am Soc Nephrol
Title: Inhibitory smads and tgf-Beta signaling in glomerular cells.
Volume: 13
Issue: 11
Pages: 2657-66
Publication
First Author: Saurus P
Year: 2017
Journal: Sci Rep
Title: Inhibition of SHIP2 in CD2AP-deficient podocytes ameliorates reactive oxygen species generation but aggravates apoptosis.
Volume: 7
Issue: 1
Pages: 10731
Publication  
First Author: Kuusela S
Year: 2016
Journal: Cell Death Dis
Title: Tankyrase inhibition aggravates kidney injury in the absence of CD2AP.
Volume: 7
Pages: e2302
Publication
First Author: Tossidou I
Year: 2012
Journal: Mol Cell Biol
Title: CD2AP regulates SUMOylation of CIN85 in podocytes.
Volume: 32
Issue: 6
Pages: 1068-79
Publication
First Author: Wasik AA
Year: 2012
Journal: Mol Biol Cell
Title: Septin 7 forms a complex with CD2AP and nephrin and regulates glucose transporter trafficking.
Volume: 23
Issue: 17
Pages: 3370-9
Publication
First Author: Tolvanen TA
Year: 2015
Journal: J Cell Sci
Title: Lack of CD2AP disrupts Glut4 trafficking and attenuates glucose uptake in podocytes.
Volume: 128
Issue: 24
Pages: 4588-600
Publication
First Author: Cochran JN
Year: 2015
Journal: Hum Mol Genet
Title: The Alzheimer's disease risk factor CD2AP maintains blood-brain barrier integrity.
Volume: 24
Issue: 23
Pages: 6667-74
Publication
First Author: Ojelade SA
Year: 2019
Journal: Cell Rep
Title: cindr, the Drosophila Homolog of the CD2AP Alzheimer's Disease Risk Gene, Is Required for Synaptic Transmission and Proteostasis.
Volume: 28
Issue: 7
Pages: 1799-1813.e5
Publication
First Author: Tossidou I
Year: 2007
Journal: J Biol Chem
Title: CD2AP/CIN85 balance determines receptor tyrosine kinase signaling response in podocytes.
Volume: 282
Issue: 10
Pages: 7457-64
Publication
First Author: Srivatsan S
Year: 2013
Journal: J Immunol
Title: CD2-associated protein regulates plasmacytoid dendritic cell migration, but is dispensable for their development and cytokine production.
Volume: 191
Issue: 12
Pages: 5933-40
Allele
Name: transgene insertion 564, Anthony Rosenzweig
Allele Type: Transgenic
Attribute String: Constitutively active, Inserted expressed sequence
Allele
Name: transgene insertion 20, Anthony Rosenzweig
Allele Type: Transgenic
Attribute String: Constitutively active, Inserted expressed sequence
Strain
Attribute String: transgenic, mutant stock
Publication  
First Author: Hadas R
Year: 2020
Journal: JCI Insight
Title: Hyaluronan control of the primary vascular barrier during early mouse pregnancy is mediated by uterine NK cells.
Volume: 5
Issue: 22
Allele
Name: transgene insertion 2, William Muller
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
Allele
Name: leukocyte-associated Ig-like receptor 1; targeted mutation 1, John E Coligan
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
Allele
Name: transgene insertion 138, M Permutt
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
Allele  
Name: tensin 2; endonuclease-mediated mutation 1, Nobuya Sasaki
Allele Type: Endonuclease-mediated
Allele  
Name: Rous sarcoma oncogene; targeted mutation 1, Goro Kato
Allele Type: Targeted
Allele  
Name: Rous sarcoma oncogene; targeted mutation 2, Goro Kato
Allele Type: Targeted
Genotype
Symbol: Cd2ap/Cd2ap
Background: involves: 129X1/SvJ
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Cd2ap/Cd2ap<+>
Background: Not Specified
Zygosity: ht
Has Mutant Allele: true
Publication
First Author: Siyanova EY
Year: 1994
Journal: Oncogene
Title: Tyrosine kinase gene expression in the mouse small intestine.
Volume: 9
Issue: 7
Pages: 2053-7
Publication
First Author: Ito Y
Year: 1994
Journal: Eur J Biochem
Title: Structural analysis of the functional gene and pseudogene encoding the murine granulocyte colony-stimulating-factor receptor.
Volume: 220
Issue: 3
Pages: 881-91
Publication
First Author: Takata H
Year: 2000
Journal: Genes Cells
Title: A hrs binding protein having a Src homology 3 domain is involved in intracellular degradation of growth factors and their receptors.
Volume: 5
Issue: 1
Pages: 57-69
Publication
First Author: Sekerková G
Year: 2003
Journal: J Neurosci
Title: Novel espin actin-bundling proteins are localized to Purkinje cell dendritic spines and bind the Src homology 3 adapter protein insulin receptor substrate p53.
Volume: 23
Issue: 4
Pages: 1310-9
Publication
First Author: Li JM
Year: 2007
Journal: Mol Endocrinol
Title: Angiotensin II-induced neural differentiation via angiotensin II type 2 (AT2) receptor-MMS2 cascade involving interaction between AT2 receptor-interacting protein and Src homology 2 domain-containing protein-tyrosine phosphatase 1.
Volume: 21
Issue: 2
Pages: 499-511
Publication
First Author: Dahl ME
Year: 2000
Journal: Genes Cells
Title: Association of Lyn tyrosine kinase to the GM-CSF and IL-3 receptor common betac subunit and role of Src tyrosine kinases in DNA synthesis and anti-apoptosis.
Volume: 5
Issue: 2
Pages: 143-53
Publication
First Author: Timson Gauen LK
Year: 1996
Journal: J Cell Biol
Title: Multiple features of the p59fyn src homology 4 domain define a motif for immune-receptor tyrosine-based activation motif (ITAM) binding and for plasma membrane localization.
Volume: 133
Issue: 5
Pages: 1007-15
Publication
First Author: Takemoto Y
Year: 1996
Journal: Int Immunol
Title: Distinct binding patterns of HS1 to the Src SH2 and SH3 domains reflect possible mechanisms of recruitment and activation of downstream molecules.
Volume: 8
Issue: 11
Pages: 1699-705
Publication
First Author: Johnson TM
Year: 2000
Journal: J Biol Chem
Title: Modulation of the catalytic activity of the Src family tyrosine kinase Hck by autophosphorylation at a novel site in the unique domain.
Volume: 275
Issue: 43
Pages: 33353-64
Publication
First Author: Liu L
Year: 1997
Journal: J Biol Chem
Title: The Src homology 2 (SH2) domain of SH2-containing inositol phosphatase (SHIP) is essential for tyrosine phosphorylation of SHIP, its association with Shc, and its induction of apoptosis.
Volume: 272
Issue: 14
Pages: 8983-8
Publication
First Author: Lamkin TD
Year: 1997
Journal: J Biol Chem
Title: Shc interaction with Src homology 2 domain containing inositol phosphatase (SHIP) in vivo requires the Shc-phosphotyrosine binding domain and two specific phosphotyrosines on SHIP.
Volume: 272
Issue: 16
Pages: 10396-401
Publication
First Author: Tridandapani S
Year: 2002
Journal: J Immunol
Title: Src homology 2 domain-containing inositol polyphosphate phosphatase regulates NF-kappa B-mediated gene transcription by phagocytic Fc gamma Rs in human myeloid cells.
Volume: 169
Issue: 8
Pages: 4370-8
Publication
First Author: Nomme J
Year: 2011
Journal: J Biol Chem
Title: The Src homology 3 domain is required for junctional adhesion molecule binding to the third PDZ domain of the scaffolding protein ZO-1.
Volume: 286
Issue: 50
Pages: 43352-60
Publication
First Author: Delbrück H
Year: 2002
Journal: J Biol Chem
Title: An Src homology 3-like domain is responsible for dimerization of the repressor protein KorB encoded by the promiscuous IncP plasmid RP4.
Volume: 277
Issue: 6
Pages: 4191-8
Publication
First Author: Feese MD
Year: 2001
Journal: J Biol Chem
Title: Crystal structure of the iron-dependent regulator from Mycobacterium tuberculosis at 2.0-A resolution reveals the Src homology domain 3-like fold and metal binding function of the third domain.
Volume: 276
Issue: 8
Pages: 5959-66
Publication
First Author: Ziemnicka-Kotula D
Year: 1998
Journal: J Biol Chem
Title: Identification of a candidate human spectrin Src homology 3 domain-binding protein suggests a general mechanism of association of tyrosine kinases with the spectrin-based membrane skeleton.
Volume: 273
Issue: 22
Pages: 13681-92
Publication
First Author: Tu Y
Year: 1998
Journal: Mol Biol Cell
Title: Nck-2, a novel Src homology2/3-containing adaptor protein that interacts with the LIM-only protein PINCH and components of growth factor receptor kinase-signaling pathways.
Volume: 9
Issue: 12
Pages: 3367-82
Publication
First Author: Tan M
Year: 2006
Journal: Oncogene
Title: Upregulation and activation of PKC alpha by ErbB2 through Src promotes breast cancer cell invasion that can be blocked by combined treatment with PKC alpha and Src inhibitors.
Volume: 25
Issue: 23
Pages: 3286-95
Publication
First Author: Rouka E
Year: 2015
Journal: J Biol Chem
Title: Differential Recognition Preferences of the Three Src Homology 3 (SH3) Domains from the Adaptor CD2-associated Protein (CD2AP) and Direct Association with Ras and Rab Interactor 3 (RIN3).
Volume: 290
Issue: 42
Pages: 25275-92
Publication
First Author: Yogo K
Year: 2006
Journal: Endocrinology
Title: Src homology 2 (SH2)-containing 5'-inositol phosphatase localizes to podosomes, and the SH2 domain is implicated in the attenuation of bone resorption in osteoclasts.
Volume: 147
Issue: 7
Pages: 3307-17
Publication
First Author: Suzuki-Inoue K
Year: 2001
Journal: J Biol Chem
Title: Rhodocytin induces platelet aggregation by interacting with glycoprotein Ia/IIa (GPIa/IIa, Integrin alpha 2beta 1). Involvement of GPIa/IIa-associated src and protein tyrosine phosphorylation.
Volume: 276
Issue: 2
Pages: 1643-52
Publication
First Author: King TR
Year: 2000
Journal: J Biol Chem
Title: Using a phage display library to identify basic residues in A-Raf required to mediate binding to the Src homology 2 domains of the p85 subunit of phosphatidylinositol 3'-kinase.
Volume: 275
Issue: 46
Pages: 36450-6
Publication
First Author: Matsui C
Year: 2008
Journal: J Biol Chem
Title: Identification of a link between the SAMP repeats of adenomatous polyposis coli tumor suppressor and the Src homology 3 domain of DDEF.
Volume: 283
Issue: 47
Pages: 33006-20
Publication
First Author: Tsuji S
Year: 2001
Journal: J Exp Med
Title: B cell adaptor containing src homology 2 domain (BASH) links B cell receptor signaling to the activation of hematopoietic progenitor kinase 1.
Volume: 194
Issue: 4
Pages: 529-39
Publication
First Author: Aspenström P
Year: 2006
Journal: Exp Cell Res
Title: The diaphanous-related formin DAAM1 collaborates with the Rho GTPases RhoA and Cdc42, CIP4 and Src in regulating cell morphogenesis and actin dynamics.
Volume: 312
Issue: 12
Pages: 2180-94
Publication
First Author: Tridandapani S
Year: 1999
Journal: J Immunol
Title: Protein interactions of Src homology 2 (SH2) domain-containing inositol phosphatase (SHIP): association with Shc displaces SHIP from FcgammaRIIb in B cells.
Volume: 162
Issue: 3
Pages: 1408-14
Publication
First Author: Andrews TD
Year: 2012
Journal: Open Biol
Title: Massively parallel sequencing of the mouse exome to accurately identify rare, induced mutations: an immediate source for thousands of new mouse models.
Volume: 2
Issue: 5
Pages: 120061
Publication
First Author: Rizzuto G
Year: 2022
Journal: Nature
Title: Establishment of fetomaternal tolerance through glycan-mediated B cell suppression.
Volume: 603
Issue: 7901
Pages: 497-502
Publication
First Author: Nelson BR
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Skeletal muscle-specific T-tubule protein STAC3 mediates voltage-induced Ca2+ release and contractility.
Volume: 110
Issue: 29
Pages: 11881-6
Publication
First Author: Hawley SP
Year: 2011
Journal: Dev Dyn
Title: Expression patterns of ShcD and Shc family adaptor proteins during mouse embryonic development.
Volume: 240
Issue: 1
Pages: 221-31
Publication
First Author: Christy BA
Year: 1991
Journal: Proc Natl Acad Sci U S A
Title: An Id-related helix-loop-helix protein encoded by a growth factor-inducible gene.
Volume: 88
Issue: 5
Pages: 1815-9
Publication
First Author: Lee GH
Year: 1995
Journal: Genetics
Title: Identification of hepatocarcinogen-resistance genes in DBA/2 mice.
Volume: 139
Issue: 1
Pages: 387-95
Publication
First Author: Tamm C
Year: 2011
Journal: J Cell Sci
Title: Regulation of mouse embryonic stem cell self-renewal by a Yes-YAP-TEAD2 signaling pathway downstream of LIF.
Volume: 124
Issue: Pt 7
Pages: 1136-44
Publication
First Author: Wolf I
Year: 2002
Journal: Mol Cell Biol
Title: Gab3, a new DOS/Gab family member, facilitates macrophage differentiation.
Volume: 22
Issue: 1
Pages: 231-44
Publication
First Author: Hartweger H
Year: 2014
Journal: J Immunol
Title: Themis2 is not required for B cell development, activation, and antibody responses.
Volume: 193
Issue: 2
Pages: 700-7
Publication
First Author: Chen H
Year: 1995
Journal: Genomics
Title: cDNA cloning, tissue distribution, and chromosomal localization of Ocp2, a gene encoding a putative transcription-associated factor predominantly expressed in the auditory organs.
Volume: 27
Issue: 3
Pages: 389-98
Publication
First Author: Yoon SH
Year: 2009
Journal: FEBS Lett
Title: Lyn inhibits osteoclast differentiation by interfering with PLCgamma1-mediated Ca2+ signaling.
Volume: 583
Issue: 7
Pages: 1164-70
Protein
Organism: Mus musculus/domesticus
Length: 629  
Fragment?: false
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein
Organism: Mus musculus/domesticus
Length: 1000  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 232  
Fragment?: false
Publication
First Author: Suen KL
Year: 1993
Journal: Mol Cell Biol
Title: Molecular cloning of the mouse grb2 gene: differential interaction of the Grb2 adaptor protein with epidermal growth factor and nerve growth factor receptors.
Volume: 13
Issue: 9
Pages: 5500-12
Publication
First Author: Minichiello L
Year: 2002
Journal: Neuron
Title: Mechanism of TrkB-mediated hippocampal long-term potentiation.
Volume: 36
Issue: 1
Pages: 121-37
Publication
First Author: Kirchgessner H
Year: 2001
Journal: J Exp Med
Title: The transmembrane adaptor protein TRIM regulates T cell receptor (TCR) expression and TCR-mediated signaling via an association with the TCR zeta chain.
Volume: 193
Issue: 11
Pages: 1269-84
Publication
First Author: Uhles S
Year: 2007
Journal: FASEB J
Title: Selective gene activation by spatial segregation of insulin receptor B signaling.
Volume: 21
Issue: 7
Pages: 1609-21
Publication
First Author: Sakaue M
Year: 1995
Journal: Mol Cell Biol
Title: A dominant-negative mutant of mSOS1 inhibits insulin-induced Ras activation and reveals Ras-dependent and -independent insulin signaling pathways.
Volume: 15
Issue: 1
Pages: 379-88
Publication
First Author: Galisteo ML
Year: 1995
Journal: J Biol Chem
Title: Tyrosine phosphorylation of the c-cbl proto-oncogene protein product and association with epidermal growth factor (EGF) receptor upon EGF stimulation.
Volume: 270
Issue: 35
Pages: 20242-5
Publication
First Author: Smith MJ
Year: 2010
Journal: EMBO J
Title: The PTB domain of ShcA couples receptor activation to the cytoskeletal regulator IQGAP1.
Volume: 29
Issue: 5
Pages: 884-96
Publication
First Author: Buerger C
Year: 2003
Journal: J Biol Chem
Title: Sequence-specific peptide aptamers, interacting with the intracellular domain of the epidermal growth factor receptor, interfere with Stat3 activation and inhibit the growth of tumor cells.
Volume: 278
Issue: 39
Pages: 37610-21
Publication
First Author: Lin S
Year: 2011
Journal: J Biol Chem
Title: Mutant p53 disrupts role of ShcA protein in balancing Smad protein-dependent and -independent signaling activity of transforming growth factor-β (TGF-β).
Volume: 286
Issue: 51
Pages: 44023-44034
Publication
First Author: Wilks AF
Year: 1989
Journal: Gene
Title: The application of the polymerase chain reaction to cloning members of the protein tyrosine kinase family.
Volume: 85
Issue: 1
Pages: 67-74
Publication
First Author: Ben-David Y
Year: 1991
Journal: EMBO J
Title: A mammalian protein kinase with potential for serine/threonine and tyrosine phosphorylation is related to cell cycle regulators.
Volume: 10
Issue: 2
Pages: 317-25
Publication
First Author: Akilesh S
Year: 2001
Journal: J Immunol
Title: Efficient chromosomal mapping of a methylcholanthrene-induced tumor antigen by CTL immunoselection.
Volume: 167
Issue: 9
Pages: 5143-9
Publication
First Author: Ichikawa N
Year: 2009
Journal: J Cell Sci
Title: Binding of laminin-1 to monosialoganglioside GM1 in lipid rafts is crucial for neurite outgrowth.
Volume: 122
Issue: Pt 2
Pages: 289-99
Publication
First Author: Serfas MS
Year: 1993
Journal: Am J Physiol
Title: HNF-1 alpha and HNF-1 beta expression in mouse intestinal crypts.
Volume: 265
Issue: 3 Pt 1
Pages: G506-13
Publication
First Author: Valenzuela DM
Year: 1995
Journal: Genomics
Title: Genomic organization and chromosomal localization of the human and mouse genes encoding the alpha receptor component for ciliary neurotrophic factor.
Volume: 25
Issue: 1
Pages: 157-63
Publication  
First Author: Kurosaki T
Year: 1999
Journal: Annu Rev Immunol
Title: Genetic analysis of B cell antigen receptor signaling.
Volume: 17
Pages: 555-92
Publication
First Author: Texido G
Year: 2000
Journal: Mol Cell Biol
Title: The B-cell-specific Src-family kinase Blk is dispensable for B-cell development and activation.
Volume: 20
Issue: 4
Pages: 1227-33
Publication
First Author: Davidson D
Year: 2003
Journal: Mol Cell Biol
Title: Phosphorylation-dependent regulation of T-cell activation by PAG/Cbp, a lipid raft-associated transmembrane adaptor.
Volume: 23
Issue: 6
Pages: 2017-28
Publication
First Author: Swindell WR
Year: 2009
Journal: Exp Gerontol
Title: Accelerated failure time models provide a useful statistical framework for aging research.
Volume: 44
Issue: 3
Pages: 190-200
Publication
First Author: Yi T
Year: 2015
Journal: Immunity
Title: Splenic Dendritic Cells Survey Red Blood Cells for Missing Self-CD47 to Trigger Adaptive Immune Responses.
Volume: 43
Issue: 4
Pages: 764-75
Publication
First Author: Rinke de Wit TF
Year: 1996
Journal: Int Immunol
Title: Expression of tyrosine kinase gene in mouse thymic stromal cells.
Volume: 8
Issue: 11
Pages: 1787-95
Publication
First Author: Guo A
Year: 2014
Journal: Mol Cell Proteomics
Title: Immunoaffinity enrichment and mass spectrometry analysis of protein methylation.
Volume: 13
Issue: 1
Pages: 372-87
Strain
Attribute String: Not specified
Genotype
Symbol: Shc2/Shc2 Shc3/Shc3
Background: involves: 129
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Fgr/Fgr Hck/Hck
Background: involves: 129S7/SvEvBrd * C57BL/6J
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Blk/Blk Fyn/Fyn Lyn/Lyn
Background: either: B6.129-Lyn Fyn Blk or (involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6)
Zygosity: cx
Has Mutant Allele: true
Genotype
Symbol: Igh/Igh Lyn/Lyn
Background: involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6
Zygosity: cx
Has Mutant Allele: true