| Type |
Details |
Score |
| Genotype |
| Symbol: |
Celsr1/Celsr1 |
| Background: |
involves: 129S1/Sv * 129X1/SvJ |
| Zygosity: |
hm |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Celsr2/Celsr2 |
| Background: |
involves: 129S5/SvEvBrd * C57BL/6J |
| Zygosity: |
hm |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Ccbe1/Ccbe1 |
| Background: |
involves: 129S5/SvEvBrd |
| Zygosity: |
hm |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Ccbe1/Ccbe1 |
| Background: |
either: B6.129-Ccbe1 or (involves: 129 * C57BL/6) |
| Zygosity: |
hm |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Celsr1/Celsr1 |
| Background: |
STOCK Celsr1/GrsrJ |
| Zygosity: |
hm |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Eogt/Eogt |
| Background: |
involves: C57BL/6J * DBA/2 |
| Zygosity: |
hm |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Eogt/Eogt Tg(Tek-cre)1Ywa/? |
| Background: |
involves: C57BL/6 * C57BL/6J * SJL |
| Zygosity: |
cn |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Ccbe1/Ccbe1 |
| Background: |
C57BL/6NCrl-Ccbe1/MbpMmucd |
| Zygosity: |
hm |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Celsr1/Celsr1 |
| Background: |
C57BL/6N-Celsr1/MbpMmucd |
| Zygosity: |
hm |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Dner/Dner |
| Background: |
C57BL/6N-Dner/Ieg |
| Zygosity: |
hm |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Vwce/Vwce |
| Background: |
C57BL/6N-Vwce/BayMmucd |
| Zygosity: |
hm |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Ccbe1/Ccbe1 |
| Background: |
involves: 129S5/SvEvBrd * C57BL/6 |
| Zygosity: |
hm |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Celsr1/Celsr1 |
| Background: |
B6.Cg-Celsr1 |
| Zygosity: |
hm |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Celsr2/Celsr2 |
| Background: |
B6.Cg-Celsr2 |
| Zygosity: |
hm |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Celsr1/Celsr1 |
| Background: |
involves: 129 * C57BL/6 |
| Zygosity: |
hm |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Celsr1/Celsr1 |
| Background: |
involves: 129S1/Sv * 129X1/SvJ * C57BL/6NCrl |
| Zygosity: |
hm |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Celsr3/Celsr3 |
| Background: |
involves: 129P2/OlaHsd * C57BL/6 * CD-1 |
| Zygosity: |
hm |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Zhao L |
| Year: |
2022 |
| Journal: |
Sex Dev |
| Title: |
Functional Analysis of Mmd2 and Related PAQR Genes During Sex Determination in Mice. |
| Volume: |
16 |
| Issue: |
4 |
| Pages: |
270-282 |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
159
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
233
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
103
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Protein Domain |
| Type: |
Family |
| Description: |
Asteroid plays a possible role in EGF receptor signalling []. |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
396
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
296
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
297
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| GO Term |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
1221
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
705
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
1174
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
705
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
810
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
810
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
705
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
928
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
1174
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Shafer B |
| Year: |
2011 |
| Journal: |
Dev Cell |
| Title: |
Vangl2 promotes Wnt/planar cell polarity-like signaling by antagonizing Dvl1-mediated feedback inhibition in growth cone guidance. |
| Volume: |
20 |
| Issue: |
2 |
| Pages: |
177-91 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Onishi K |
| Year: |
2013 |
| Journal: |
J Neurosci |
| Title: |
Antagonistic functions of Dishevelleds regulate Frizzled3 endocytosis via filopodia tips in Wnt-mediated growth cone guidance. |
| Volume: |
33 |
| Issue: |
49 |
| Pages: |
19071-85 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Jinushi M |
| Year: |
2007 |
| Journal: |
J Clin Invest |
| Title: |
MFG-E8-mediated uptake of apoptotic cells by APCs links the pro- and antiinflammatory activities of GM-CSF. |
| Volume: |
117 |
| Issue: |
7 |
| Pages: |
1902-13 |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
205
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
187
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
563
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
256
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
344
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
1056
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
317
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
257
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
256
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
346
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
346
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
3083
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
3718
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
3330
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
763
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Wang Y |
| Year: |
2016 |
| Journal: |
Dev Biol |
| Title: |
Patterning of papillae on the mouse tongue: A system for the quantitative assessment of planar cell polarity signaling. |
| Volume: |
419 |
| Issue: |
2 |
| Pages: |
298-310 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Qu Y |
| Year: |
2010 |
| Journal: |
J Neurosci |
| Title: |
Atypical cadherins Celsr1-3 differentially regulate migration of facial branchiomotor neurons in mice. |
| Volume: |
30 |
| Issue: |
28 |
| Pages: |
9392-401 |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
1062
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Jüttner R |
| Year: |
2005 |
| Journal: |
Neuron |
| Title: |
Impaired synapse function during postnatal development in the absence of CALEB, an EGF-like protein processed by neuronal activity. |
| Volume: |
46 |
| Issue: |
2 |
| Pages: |
233-45 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Nakagawa T |
| Year: |
2005 |
| Journal: |
Dev Dyn |
| Title: |
Characterization of a human rhomboid homolog, p100hRho/RHBDF1, which interacts with TGF-alpha family ligands. |
| Volume: |
233 |
| Issue: |
4 |
| Pages: |
1315-31 |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
820
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
833
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
566
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
478
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
833
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Feng J |
| Year: |
2016 |
| Journal: |
Cereb Cortex |
| Title: |
Celsr3 and Fzd3 Organize a Pioneer Neuron Scaffold to Steer Growing Thalamocortical Axons. |
| Volume: |
26 |
| Issue: |
7 |
| Pages: |
3323-34 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Tissir F |
| Year: |
2010 |
| Journal: |
Nat Neurosci |
| Title: |
Lack of cadherins Celsr2 and Celsr3 impairs ependymal ciliogenesis, leading to fatal hydrocephalus. |
| Volume: |
13 |
| Issue: |
6 |
| Pages: |
700-7 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Thomson BR |
| Year: |
2021 |
| Journal: |
Nat Commun |
| Title: |
Cellular crosstalk regulates the aqueous humor outflow pathway and provides new targets for glaucoma therapies. |
| Volume: |
12 |
| Issue: |
1 |
| Pages: |
6072 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Krebs LT |
| Year: |
2001 |
| Journal: |
Dev Biol |
| Title: |
The Nrarp gene encodes an ankyrin-repeat protein that is transcriptionally regulated by the notch signaling pathway. |
| Volume: |
238 |
| Issue: |
1 |
| Pages: |
110-9 |
|
•
•
•
•
•
|
| Allele |
| Name: |
notch 1; targeted mutation 1, Ronald L Conlon |
| Allele Type: |
Targeted |
| Attribute String: |
Null/knockout |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Swiatek PJ |
| Year: |
1994 |
| Journal: |
Genes Dev |
| Title: |
Notch1 is essential for postimplantation development in mice. |
| Volume: |
8 |
| Issue: |
6 |
| Pages: |
707-19 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Nigam V |
| Year: |
2009 |
| Journal: |
J Mol Cell Cardiol |
| Title: |
Notch1 represses osteogenic pathways in aortic valve cells. |
| Volume: |
47 |
| Issue: |
6 |
| Pages: |
828-34 |
|
•
•
•
•
•
|
| Allele |
| Name: |
neuregulin 1; targeted mutation 1, Genentech |
| Allele Type: |
Targeted |
| Attribute String: |
Null/knockout |
|
•
•
•
•
•
|
| Allele |
| Name: |
neuregulin 1; targeted mutation 2, Carmen Birchmeier |
| Allele Type: |
Targeted |
| Attribute String: |
Null/knockout, Reporter |
|
•
•
•
•
•
|
| Allele |
| Name: |
delta like canonical Notch ligand 3; targeted mutation 1, Rosa Beddington |
| Allele Type: |
Targeted |
| Attribute String: |
Null/knockout |
|
•
•
•
•
•
|
| Allele |
| Name: |
chondroitin sulfate proteoglycan 5; targeted mutation 1, Fritz G Rathjen |
| Allele Type: |
Targeted |
| Attribute String: |
Null/knockout |
|
•
•
•
•
•
|
| Allele |
| Name: |
transgene insertion, Sergio A Lira |
| Allele Type: |
Transgenic |
| Attribute String: |
Inserted expressed sequence, Reporter |
|
•
•
•
•
•
|
| Allele |
| Name: |
neuregulin 2; targeted mutation 1, Andres Buonanno |
| Allele Type: |
Targeted |
| Attribute String: |
Conditional ready |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Notch1/Notch1 |
| Background: |
involves: 129S1/Sv * C57BL/6 |
| Zygosity: |
hm |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Notch1/Notch1<+> |
| Background: |
involves: 129S1/Sv * C57BL/6 |
| Zygosity: |
ht |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Notch1/Notch1<+> |
| Background: |
Not Specified |
| Zygosity: |
ht |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Notch1/Notch1 |
| Background: |
Not Specified |
| Zygosity: |
hm |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Notch1/Notch1<+> |
| Background: |
129S6.129S1-Notch1 |
| Zygosity: |
ht |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
2571
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
2559
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
870
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
2337
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
2571
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
2559
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
2559
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
2571
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
350
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Hermle T |
| Year: |
2013 |
| Journal: |
EMBO J |
| Title: |
Drosophila ATP6AP2/VhaPRR functions both as a novel planar cell polarity core protein and a regulator of endosomal trafficking. |
| Volume: |
32 |
| Issue: |
2 |
| Pages: |
245-59 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Xie Z |
| Year: |
2022 |
| Journal: |
Cell Rep |
| Title: |
Phosphatidylinositol transfer protein/planar cell polarity axis regulates neocortical morphogenesis by supporting interkinetic nuclear migration. |
| Volume: |
39 |
| Issue: |
9 |
| Pages: |
110869 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Fenstermaker AG |
| Year: |
2010 |
| Journal: |
J Neurosci |
| Title: |
Wnt/planar cell polarity signaling controls the anterior-posterior organization of monoaminergic axons in the brainstem. |
| Volume: |
30 |
| Issue: |
47 |
| Pages: |
16053-64 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Sasselli V |
| Year: |
2013 |
| Journal: |
J Clin Invest |
| Title: |
Planar cell polarity genes control the connectivity of enteric neurons. |
| Volume: |
123 |
| Issue: |
4 |
| Pages: |
1763-72 |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
1192
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
493
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
387
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Housset M |
| Year: |
2024 |
| Journal: |
Dev Cell |
| Title: |
Identification of a non-canonical planar cell polarity pathway triggered by light in the developing mouse retina. |
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| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
Mus caroli |
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| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
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