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Search results 3801 to 3900 out of 4967 for Hc

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Type Details Score
Publication
First Author: He F
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: Multiscale characterization of the mineral phase at skeletal sites of breast cancer metastasis.
Volume: 114
Issue: 40
Pages: 10542-10547
Publication
First Author: Huang PY
Year: 2017
Journal: Nat Genet
Title: Lgr6 is a stem cell marker in mouse skin squamous cell carcinoma.
Volume: 49
Issue: 11
Pages: 1624-1632
Publication
First Author: Yang D
Year: 2018
Journal: Cancer Discov
Title: Intertumoral Heterogeneity in SCLC Is Influenced by the Cell Type of Origin.
Volume: 8
Issue: 10
Pages: 1316-1331
Publication
First Author: Lee HW
Year: 2019
Journal: PLoS One
Title: Enhanced cardiac expression of two isoforms of matrix metalloproteinase-2 in experimental diabetes mellitus.
Volume: 14
Issue: 8
Pages: e0221798
Publication
First Author: Heier C
Year: 2015
Journal: J Biol Chem
Title: G0/G1 Switch Gene 2 Regulates Cardiac Lipolysis.
Volume: 290
Issue: 43
Pages: 26141-50
Publication
First Author: Piálek J
Year: 2008
Journal: J Hered
Title: Development of unique house mouse resources suitable for evolutionary studies of speciation.
Volume: 99
Issue: 1
Pages: 34-44
Publication
First Author: Reis MB
Year: 2020
Journal: Nat Commun
Title: Interleukin-1 receptor-induced PGE2 production controls acetylcholine-mediated cardiac dysfunction and mortality during scorpion envenomation.
Volume: 11
Issue: 1
Pages: 5433
Publication      
First Author: Teixeira VP
Year: 2020
Journal: Am J Physiol Cell Physiol
Title: Increased cholinergic activity under conditions of low estrogen leads to adverse cardiac remodeling.
Publication
First Author: Kovalenko A
Year: 2021
Journal: Cancer Res
Title: Therapeutic Targeting of DGKA-Mediated Macropinocytosis Leads to Phospholipid Reprogramming in Tuberous Sclerosis Complex.
Volume: 81
Issue: 8
Pages: 2086-2100
Publication
First Author: Norrmén C
Year: 2014
Journal: Cell Rep
Title: mTORC1 controls PNS myelination along the mTORC1-RXRγ-SREBP-lipid biosynthesis axis in Schwann cells.
Volume: 9
Issue: 2
Pages: 646-60
Publication
First Author: Wu L
Year: 2021
Journal: Kidney Int
Title: Annexin A1 alleviates kidney injury by promoting the resolution of inflammation in diabetic nephropathy.
Volume: 100
Issue: 1
Pages: 107-121
Publication
First Author: Paschall AV
Year: 2015
Journal: J Immunol
Title: IFN regulatory factor 8 represses GM-CSF expression in T cells to affect myeloid cell lineage differentiation.
Volume: 194
Issue: 5
Pages: 2369-79
Publication
First Author: Xi Y
Year: 2021
Journal: Sci Adv
Title: The anti-fibrotic drug pirfenidone inhibits liver fibrosis by targeting the small oxidoreductase glutaredoxin-1.
Volume: 7
Issue: 36
Pages: eabg9241
Publication  
First Author: Wang J
Year: 2021
Journal: Proc Natl Acad Sci U S A
Title: Interleukin-6 mediates PSAT1 expression and serine metabolism in TSC2-deficient cells.
Volume: 118
Issue: 39
Publication
First Author: Moon MY
Year: 2013
Journal: Cell Signal
Title: Involvement of small GTPase RhoA in the regulation of superoxide production in BV2 cells in response to fibrillar Aβ peptides.
Volume: 25
Issue: 9
Pages: 1861-9
Publication
First Author: Lim JS
Year: 2015
Journal: Nat Med
Title: Brain somatic mutations in MTOR cause focal cortical dysplasia type II leading to intractable epilepsy.
Volume: 21
Issue: 4
Pages: 395-400
Publication
First Author: Hoffman MT
Year: 2021
Journal: Cell Mol Gastroenterol Hepatol
Title: The Gustatory Sensory G-Protein GNAT3 Suppresses Pancreatic Cancer Progression in Mice.
Volume: 11
Issue: 2
Pages: 349-369
Publication
First Author: Yan M
Year: 2016
Journal: J Immunol
Title: Cutting Edge: Expression of IRF8 in Gastric Epithelial Cells Confers Protective Innate Immunity against Helicobacter pylori Infection.
Volume: 196
Issue: 5
Pages: 1999-2003
Publication  
First Author: Yang J
Year: 2023
Journal: Cancer Lett
Title: Miz1 promotes KRAS-driven lung tumorigenesis by repressing the protocadherin Pcdh10.
Volume: 555
Pages: 216025
Publication
First Author: Scales MK
Year: 2022
Journal: PLoS Genet
Title: Combinatorial Gli activity directs immune infiltration and tumor growth in pancreatic cancer.
Volume: 18
Issue: 7
Pages: e1010315
Publication  
First Author: Sieow JL
Year: 2023
Journal: Int J Mol Sci
Title: Conditional Knockout of Hypoxia-Inducible Factor 1-Alpha in Tumor-Infiltrating Neutrophils Protects against Pancreatic Ductal Adenocarcinoma.
Volume: 24
Issue: 1
Publication
First Author: Wang IH
Year: 2022
Journal: Nat Neurosci
Title: Spatial transcriptomic reconstruction of the mouse olfactory glomerular map suggests principles of odor processing.
Volume: 25
Issue: 4
Pages: 484-492
Publication
First Author: Rathjen T
Year: 2022
Journal: Arterioscler Thromb Vasc Biol
Title: Endothelial Cell Insulin Signaling Regulates CXCR4 (C-X-C Motif Chemokine Receptor 4) and Limits Leukocyte Adhesion to Endothelium.
Volume: 42
Issue: 7
Pages: e217-e227
Publication
First Author: Sardar D
Year: 2023
Journal: Science
Title: Induction of astrocytic Slc22a3 regulates sensory processing through histone serotonylation.
Volume: 380
Issue: 6650
Pages: eade0027
Publication
First Author: Singhal A
Year: 2024
Journal: Cancer Discov
Title: A Classical Epithelial State Drives Acute Resistance to KRAS Inhibition in Pancreatic Cancer.
Volume: 14
Issue: 11
Pages: 2122-2134
Publication
First Author: Ma R
Year: 2024
Journal: Cell Rep
Title: Vimentin modulates regulatory T cell receptor-ligand interactions at distal pole complex, leading to dysregulated host response to viral pneumonia.
Volume: 43
Issue: 12
Pages: 115056
Publication
First Author: Rahman A
Year: 2005
Journal: FEBS Lett
Title: High cholesterol diet induces tau hyperphosphorylation in apolipoprotein E deficient mice.
Volume: 579
Issue: 28
Pages: 6411-6
Publication  
First Author: Kannan-Sundhari A
Year: 2020
Journal: Front Cell Dev Biol
Title: Bromodomain Protein BRD4 Is Essential for Hair Cell Function and Survival.
Volume: 8
Pages: 576654
Publication
First Author: Oikawa T
Year: 1985
Journal: J Immunogenet
Title: Genetic differences between two substrains of NZB mice.
Volume: 12
Issue: 1
Pages: 71-3
Publication  
First Author: Taylor BA
Year: 1985
Journal: Mouse News Lett
Title: Mapping additional 7S RNA sequences.
Volume: 72
Pages: 110
Publication
First Author: Akerström B
Year: 1990
Journal: Trends Biochem Sci
Title: An intriguing member of the lipocalin protein family: alpha 1-microglobulin.
Volume: 15
Issue: 6
Pages: 240-3
Protein Domain
Type: Family
Description: The lipocalin family can be subdivided into kernal and outlier sets. The kernal lipocalins form the largest self consistent group, comprising the subfamily of alpha-1-microglobulins. The outlier lipocalins form several smaller distinct subgroups: the OBPs, the von Ebner's gland proteins, alpha-1-acid glycoproteins, tick histamine binding proteins and the nitrophorins.Alpha-1-microglobulin (A1M), also known as protein HC (for Heterogeneous Charge), is a low molecular weight protein component of plasma first discovered in pathological human urine. It is a member of the lipocalin superfamily. Although much is now known of its structure and properties, the function and physiological role of A1M remains unclear, although evidence suggests that it functions in the regulation of the immune system. A1M is known to exist in both a free form and complexed to other macromolecules: immunoglobulin A (IgA) in humans and alpha-1-inhibitor-3 in the rat. Free A1M is a monomeric protein composed of one 188 residue polypeptide and contains three cysteines, two of which (residues 75 and 173) form a conserved intra-molecular disulphide link []. A1M is glycosylated by three separate carbohydrate chains: two complex carbohydrates are N-linked to asparagines at residues 17 and 96, and the other simple carbohydrate is O-linked to threonine at position 5. 22% of the total molecular mass of the protein is derived from carbohydrate. Free A1M is extremely heterogeneous in charge, and is found tightly associated with a chromophore. This chromophoric group is covalently bound to the free cysteine residue at position 34. It also binds retinol as a major ligand, but this is probably distinct from the its covalent chromophore. The glycosylation is different between species. The principal sites of A1M synthesis are the liver and kidney. Half of all human plasma A1M (about 0.03mg/ml) forms a 1:1 complex with about 5% of plasma immunoglobulin A. The resulting macromolecular complex has a molecular weight of 200000, anda plasma concentration of 0.3mg/ml. It can exhibit both antibody activity and affect many of the biological actions of free A1M []. A1M has many affects on the immune system. It inhibits stimulation of cultured lymphocytes by protein antigens; it can induce cell division of lymphocytes, a mitogenic effect that can either be enhanced or inhibited by the action of other plasma components; it inhibits neutrophil granulocyte migration in vitro; and it inhibits chemotaxis.
HT Experiment
Series Id: GSE35888
Experiment Type: transcription profiling by array
Study Type: Baseline
Source: ArrayExpress
Strain
Attribute String: inbred strain
Strain
Attribute String: inbred strain
Strain
Attribute String: inbred strain
Strain
Attribute String: congenic, mutant strain, transgenic, major histocompatibility congenic
Strain
Attribute String: inbred strain
Strain
Attribute String: inbred strain
Strain
Attribute String: inbred strain
Strain
Attribute String: inbred strain
Publication
First Author: Town T
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: The stumpy gene is required for mammalian ciliogenesis.
Volume: 105
Issue: 8
Pages: 2853-8
Publication
First Author: Imuta Y
Year: 2009
Journal: Dev Dyn
Title: Short limbs, cleft palate, and delayed formation of flat proliferative chondrocytes in mice with targeted disruption of a putative protein kinase gene, Pkdcc (AW548124).
Volume: 238
Issue: 1
Pages: 210-22
Publication
First Author: Andrews SF
Year: 2013
Journal: J Exp Med
Title: Global analysis of B cell selection using an immunoglobulin light chain-mediated model of autoreactivity.
Volume: 210
Issue: 1
Pages: 125-42
Publication
First Author: Hofmann MA
Year: 2001
Journal: J Clin Invest
Title: Hyperhomocysteinemia enhances vascular inflammation and accelerates atherosclerosis in a murine model.
Volume: 107
Issue: 6
Pages: 675-83
Publication
First Author: Walters BJ
Year: 2017
Journal: Cell Rep
Title: In Vivo Interplay between p27Kip1, GATA3, ATOH1, and POU4F3 Converts Non-sensory Cells to Hair Cells in Adult Mice.
Volume: 19
Issue: 2
Pages: 307-320
Publication  
First Author: Hayashi Y
Year: 2021
Journal: Proc Natl Acad Sci U S A
Title: Norrie disease protein is essential for cochlear hair cell maturation.
Volume: 118
Issue: 39
Publication  
First Author: Wang T
Year: 2015
Journal: Nat Commun
Title: Lgr5+ cells regenerate hair cells via proliferation and direct transdifferentiation in damaged neonatal mouse utricle.
Volume: 6
Pages: 6613
Publication
First Author: Román E
Year: 2010
Journal: J Immunol
Title: Cutting edge: Hematopoietic-derived APCs select regulatory T cells in thymus.
Volume: 185
Issue: 7
Pages: 3819-23
Publication    
First Author: Morcom L
Year: 2021
Journal: Elife
Title: DCC regulates astroglial development essential for telencephalic morphogenesis and corpus callosum formation.
Volume: 10
Publication    
First Author: Jiang T
Year: 2017
Journal: Elife
Title: Transcription factor Emx2 controls stereociliary bundle orientation of sensory hair cells.
Volume: 6
Publication
First Author: Huyghe A
Year: 2015
Journal: Cell Rep
Title: MicroRNA-124 Regulates Cell Specification in the Cochlea through Modulation of Sfrp4/5.
Volume: 13
Issue: 1
Pages: 31-42
Publication
First Author: Yadav PS
Year: 2023
Journal: iScience
Title: Phosphate-induced activation of VEGFR2 leads to caspase-9-mediated apoptosis of hypertrophic chondrocytes.
Volume: 26
Issue: 9
Pages: 107548
Publication
First Author: Funsten MC
Year: 2023
Journal: Cell Host Microbe
Title: Microbiota-dependent proteolysis of gluten subverts diet-mediated protection against type 1 diabetes.
Volume: 31
Issue: 2
Pages: 213-227.e9
Publication  
First Author: Elkon R
Year: 2015
Journal: Nat Commun
Title: RFX transcription factors are essential for hearing in mice.
Volume: 6
Pages: 8549
Publication
First Author: Young F
Year: 1997
Journal: Immunity
Title: Constitutive Bcl-2 expression during immunoglobulin heavy chain-promoted B cell differentiation expands novel precursor B cells.
Volume: 6
Issue: 1
Pages: 23-33
Publication
First Author: Li Y
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: Sialylation on O-glycans protects platelets from clearance by liver Kupffer cells.
Volume: 114
Issue: 31
Pages: 8360-8365
Publication
First Author: Sayyid ZN
Year: 2019
Journal: Cell Rep
Title: Atoh1 Directs Regeneration and Functional Recovery of the Mature Mouse Vestibular System.
Volume: 28
Issue: 2
Pages: 312-324.e4
Publication
First Author: Schuh W
Year: 2003
Journal: J Immunol
Title: Cutting edge: signaling and cell surface expression of a mu H chain in the absence of lambda 5: a paradigm revisited.
Volume: 171
Issue: 7
Pages: 3343-7
Publication  
First Author: Kistner K
Year: 2016
Journal: Sci Rep
Title: Systemic desensitization through TRPA1 channels by capsazepine and mustard oil - a novel strategy against inflammation and pain.
Volume: 6
Pages: 28621
Publication
First Author: Richard C
Year: 2013
Journal: Dev Cell
Title: Endothelio-mesenchymal interaction controls runx1 expression and modulates the notch pathway to initiate aortic hematopoiesis.
Volume: 24
Issue: 6
Pages: 600-11
Publication
First Author: Petitpré C
Year: 2022
Journal: Nat Commun
Title: Single-cell RNA-sequencing analysis of the developing mouse inner ear identifies molecular logic of auditory neuron diversification.
Volume: 13
Issue: 1
Pages: 3878
Publication
First Author: Yamashita T
Year: 2018
Journal: PLoS Genet
Title: High-resolution transcriptional dissection of in vivo Atoh1-mediated hair cell conversion in mature cochleae identifies Isl1 as a co-reprogramming factor.
Volume: 14
Issue: 7
Pages: e1007552
Publication
First Author: Fujimoto C
Year: 2017
Journal: Cell Death Dis
Title: Autophagy is essential for hearing in mice.
Volume: 8
Issue: 5
Pages: e2780
Publication
First Author: Worth AN
Year: 2022
Journal: Cell Rep
Title: Receptor editing constrains development of phosphatidyl choline-specific B cells in V(H)12-transgenic mice.
Volume: 39
Issue: 11
Pages: 110899
Publication
First Author: Xia M
Year: 2023
Journal: Sci Adv
Title: Varying mechanical forces drive sensory epithelium formation.
Volume: 9
Issue: 44
Pages: eadf2664
Publication
First Author: Li XJ
Year: 2022
Journal: Sci Adv
Title: Follistatin promotes LIN28B-mediated supporting cell reprogramming and hair cell regeneration in the murine cochlea.
Volume: 8
Issue: 6
Pages: eabj7651
Publication
First Author: Sun Q
Year: 2024
Journal: Cell Prolif
Title: AAV-mediated Gpm6b expression supports hair cell reprogramming.
Volume: 57
Issue: 7
Pages: e13620
Publication
First Author: Xia M
Year: 2023
Journal: Stem Cell Reports
Title: Generation of innervated cochlear organoid recapitulates early development of auditory unit.
Volume: 18
Issue: 1
Pages: 319-336
Publication
First Author: Chaya T
Year: 2017
Journal: Sci Rep
Title: Versatile functional roles of horizontal cells in the retinal circuit.
Volume: 7
Issue: 1
Pages: 5540
Publication
First Author: Lee JH
Year: 2024
Journal: Nat Commun
Title: The Piezo channel is a mechano-sensitive complex component in the mammalian inner ear hair cell.
Volume: 15
Issue: 1
Pages: 526
Publication
First Author: Cortada M
Year: 2023
Journal: iScience
Title: mTORC2 regulates auditory hair cell structure and function.
Volume: 26
Issue: 9
Pages: 107687
Publication
First Author: Yao Q
Year: 2022
Journal: Mol Neurobiol
Title: Essential Role of Sptan1 in Cochlear Hair Cell Morphology and Function Via Focal Adhesion Signaling.
Volume: 59
Issue: 1
Pages: 386-404
Publication
First Author: Luo Z
Year: 2022
Journal: Proc Natl Acad Sci U S A
Title: Three distinct Atoh1 enhancers cooperate for sound receptor hair cell development.
Volume: 119
Issue: 32
Pages: e2119850119
Publication
First Author: Mills JW
Year: 2001
Journal: Infect Immun
Title: Extensive Mycobacterium bovis BCG infection of liver parenchymal cells in immunocompromised mice.
Volume: 69
Issue: 5
Pages: 3175-80
Publication
First Author: Erickson RP
Year: 2005
Journal: Life Sci
Title: Correlation of susceptibility to 6-aminonicotinamide and hydrocortisone-induced cleft palate.
Volume: 76
Issue: 18
Pages: 2071-8
Publication  
First Author: Tateya T
Year: 2019
Journal: Development
Title: Three-dimensional live imaging of Atoh1 reveals the dynamics of hair cell induction and organization in the developing cochlea.
Volume: 146
Issue: 21
Publication
First Author: Chen Y
Year: 2021
Journal: Cell Rep
Title: Generation of mature and functional hair cells by co-expression of Gfi1, Pou4f3, and Atoh1 in the postnatal mouse cochlea.
Volume: 35
Issue: 3
Pages: 109016
Publication  
First Author: Huang Y
Year: 2023
Journal: Neurosci Lett
Title: The expression of p27 in the adult vestibular sensory organs and its possible roles.
Volume: 800
Pages: 137128
Publication
First Author: Loukinov DI
Year: 2002
Journal: Proc Natl Acad Sci U S A
Title: BORIS, a novel male germ-line-specific protein associated with epigenetic reprogramming events, shares the same 11-zinc-finger domain with CTCF, the insulator protein involved in reading imprinting marks in the soma.
Volume: 99
Issue: 10
Pages: 6806-11
Publication
First Author: Spruijt CG
Year: 2013
Journal: Cell
Title: Dynamic readers for 5-(hydroxy)methylcytosine and its oxidized derivatives.
Volume: 152
Issue: 5
Pages: 1146-59
Publication
First Author: McMillin MJ
Year: 2013
Journal: Am J Hum Genet
Title: Mutations in ECEL1 cause distal arthrogryposis type 5D.
Volume: 92
Issue: 1
Pages: 150-6
Publication  
First Author: Drzewiecki K
Year: 2021
Journal: J Exp Med
Title: GIMAP5 maintains liver endothelial cell homeostasis and prevents portal hypertension.
Volume: 218
Issue: 7
Publication
First Author: Vivante A
Year: 2017
Journal: J Am Soc Nephrol
Title: A Dominant Mutation in Nuclear Receptor Interacting Protein 1 Causes Urinary Tract Malformations via Dysregulation of Retinoic Acid Signaling.
Volume: 28
Issue: 8
Pages: 2364-2376
Publication
First Author: Ansar M
Year: 2019
Journal: Am J Hum Genet
Title: Bi-allelic Variants in IQSEC1 Cause Intellectual Disability, Developmental Delay, and Short Stature.
Volume: 105
Issue: 5
Pages: 907-920
Publication
First Author: Lettice LA
Year: 2002
Journal: Proc Natl Acad Sci U S A
Title: Disruption of a long-range cis-acting regulator for Shh causes preaxial polydactyly.
Volume: 99
Issue: 11
Pages: 7548-53
Publication
First Author: Loeys BL
Year: 2005
Journal: Nat Genet
Title: A syndrome of altered cardiovascular, craniofacial, neurocognitive and skeletal development caused by mutations in TGFBR1 or TGFBR2.
Volume: 37
Issue: 3
Pages: 275-81
Publication
First Author: Lee J
Year: 2007
Journal: Plant J
Title: Salicylic acid-mediated innate immunity in Arabidopsis is regulated by SIZ1 SUMO E3 ligase.
Volume: 49
Issue: 1
Pages: 79-90
Publication
First Author: Snow AL
Year: 2012
Journal: J Exp Med
Title: Congenital B cell lymphocytosis explained by novel germline CARD11 mutations.
Volume: 209
Issue: 12
Pages: 2247-61
Publication
First Author: Dejanovic B
Year: 2015
Journal: EMBO Mol Med
Title: Simultaneous impairment of neuronal and metabolic function of mutated gephyrin in a patient with epileptic encephalopathy.
Volume: 7
Issue: 12
Pages: 1580-94
Publication
First Author: Zhang W
Year: 2021
Journal: Cell
Title: The bone microenvironment invigorates metastatic seeds for further dissemination.
Volume: 184
Issue: 9
Pages: 2471-2486.e20
Publication
First Author: Lang PA
Year: 2015
Journal: Cell Death Differ
Title: Toso regulates differentiation and activation of inflammatory dendritic cells during persistence-prone virus infection.
Volume: 22
Issue: 1
Pages: 164-73
Publication
First Author: Bhattacharya A
Year: 2015
Journal: Immunity
Title: Superoxide Dismutase 1 Protects Hepatocytes from Type I Interferon-Driven Oxidative Damage.
Volume: 43
Issue: 5
Pages: 974-86
Publication
First Author: Singh SK
Year: 2015
Journal: EMBO J
Title: Antithetical NFATc1-Sox2 and p53-miR200 signaling networks govern pancreatic cancer cell plasticity.
Volume: 34
Issue: 4
Pages: 517-30
Publication
First Author: Prévost J
Year: 2022
Journal: Cell Rep
Title: HIV-1 Vpu restricts Fc-mediated effector functions in vivo.
Volume: 41
Issue: 6
Pages: 111624
Publication
First Author: Wang D
Year: 2023
Journal: Nature
Title: GDF15 promotes weight loss by enhancing energy expenditure in muscle.
Volume: 619
Issue: 7968
Pages: 143-150
Publication
First Author: Renz BW
Year: 2018
Journal: Cancer Cell
Title: β2 Adrenergic-Neurotrophin Feedforward Loop Promotes Pancreatic Cancer.
Volume: 33
Issue: 1
Pages: 75-90.e7
Publication
First Author: Zhang Y
Year: 2020
Journal: Cancer Discov
Title: Regulatory T-cell Depletion Alters the Tumor Microenvironment and Accelerates Pancreatic Carcinogenesis.
Volume: 10
Issue: 3
Pages: 422-439
Publication
First Author: van de Leemput J
Year: 2007
Journal: PLoS Genet
Title: Deletion at ITPR1 underlies ataxia in mice and spinocerebellar ataxia 15 in humans.
Volume: 3
Issue: 6
Pages: e108
Publication
First Author: Zhang J
Year: 2020
Journal: Nat Commun
Title: Wnt-PLC-IP3-Connexin-Ca2+ axis maintains ependymal motile cilia in zebrafish spinal cord.
Volume: 11
Issue: 1
Pages: 1860