| Type |
Details |
Score |
| Publication |
| First Author: |
Sekiya S |
| Year: |
2012 |
| Journal: |
J Clin Invest |
| Title: |
Intrahepatic cholangiocarcinoma can arise from Notch-mediated conversion of hepatocytes. |
| Volume: |
122 |
| Issue: |
11 |
| Pages: |
3914-8 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
De La O JP |
| Year: |
2008 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Notch and Kras reprogram pancreatic acinar cells to ductal intraepithelial neoplasia. |
| Volume: |
105 |
| Issue: |
48 |
| Pages: |
18907-12 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Nolan E |
| Year: |
2022 |
| Journal: |
Nat Cancer |
| Title: |
Radiation exposure elicits a neutrophil-driven response in healthy lung tissue that enhances metastatic colonization. |
| Volume: |
3 |
| Issue: |
2 |
| Pages: |
173-187 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Greenwood AL |
| Year: |
2007 |
| Journal: |
Mech Dev |
| Title: |
Notch signaling reveals developmental plasticity of Pax4(+) pancreatic endocrine progenitors and shunts them to a duct fate. |
| Volume: |
124 |
| Issue: |
2 |
| Pages: |
97-107 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Cherrier M |
| Year: |
2012 |
| Journal: |
J Exp Med |
| Title: |
Notch, Id2, and RORγt sequentially orchestrate the fetal development of lymphoid tissue inducer cells. |
| Volume: |
209 |
| Issue: |
4 |
| Pages: |
729-40 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Paul MK |
| Year: |
2014 |
| Journal: |
Cell Stem Cell |
| Title: |
Dynamic changes in intracellular ROS levels regulate airway basal stem cell homeostasis through Nrf2-dependent Notch signaling. |
| Volume: |
15 |
| Issue: |
2 |
| Pages: |
199-214 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kang HM |
| Year: |
2016 |
| Journal: |
Cell Rep |
| Title: |
Sox9-Positive Progenitor Cells Play a Key Role in Renal Tubule Epithelial Regeneration in Mice. |
| Volume: |
14 |
| Issue: |
4 |
| Pages: |
861-871 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Muroyama A |
| Year: |
2016 |
| Journal: |
J Cell Biol |
| Title: |
Divergent regulation of functionally distinct γ-tubulin complexes during differentiation. |
| Volume: |
213 |
| Issue: |
6 |
| Pages: |
679-92 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Collins CA |
| Year: |
2008 |
| Journal: |
Dev Biol |
| Title: |
Dynamic regulation of retinoic acid-binding proteins in developing, adult and neoplastic skin reveals roles for beta-catenin and Notch signalling. |
| Volume: |
324 |
| Issue: |
1 |
| Pages: |
55-67 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Georgi SA |
| Year: |
2011 |
| Journal: |
Dev Neurobiol |
| Title: |
Dicer is required for the maintenance of notch signaling and gliogenic competence during mouse retinal development. |
| Volume: |
71 |
| Issue: |
12 |
| Pages: |
1153-69 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kohn A |
| Year: |
2012 |
| Journal: |
Development |
| Title: |
Cartilage-specific RBPjκ-dependent and -independent Notch signals regulate cartilage and bone development. |
| Volume: |
139 |
| Issue: |
6 |
| Pages: |
1198-212 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Feng X |
| Year: |
2023 |
| Journal: |
Dev Cell |
| Title: |
Polycomb Ezh1 maintains murine muscle stem cell quiescence through non-canonical regulation of Notch signaling. |
| Volume: |
58 |
| Issue: |
12 |
| Pages: |
1052-1070.e10 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Jeong HW |
| Year: |
2009 |
| Journal: |
J Clin Invest |
| Title: |
Inactivation of Notch signaling in the renal collecting duct causes nephrogenic diabetes insipidus in mice. |
| Volume: |
119 |
| Issue: |
11 |
| Pages: |
3290-300 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Bentley K |
| Year: |
2014 |
| Journal: |
Nat Cell Biol |
| Title: |
The role of differential VE-cadherin dynamics in cell rearrangement during angiogenesis. |
| Volume: |
16 |
| Issue: |
4 |
| Pages: |
309-21 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Lee SH |
| Year: |
2014 |
| Journal: |
Circ Res |
| Title: |
Notch pathway targets proangiogenic regulator Sox17 to restrict angiogenesis. |
| Volume: |
115 |
| Issue: |
2 |
| Pages: |
215-26 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Izumi N |
| Year: |
2012 |
| Journal: |
PLoS One |
| Title: |
Fbxw7 controls angiogenesis by regulating endothelial Notch activity. |
| Volume: |
7 |
| Issue: |
7 |
| Pages: |
e41116 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kang J |
| Year: |
2023 |
| Journal: |
JCI Insight |
| Title: |
Notch-mediated hepatocyte MCP-1 secretion causes liver fibrosis. |
| Volume: |
8 |
| Issue: |
3 |
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Novak A |
| Year: |
2000 |
| Journal: |
Genesis |
| Title: |
Z/EG, a double reporter mouse line that expresses enhanced green fluorescent protein upon Cre-mediated excision. |
| Volume: |
28 |
| Issue: |
3-4 |
| Pages: |
147-55 |
|
•
•
•
•
•
|
| Allele |
| Name: |
gene trap ROSA 26, Philippe Soriano; targeted mutation 5, Rui Benedito |
| Allele Type: |
Targeted |
| Attribute String: |
Conditional ready, Epitope tag, Inserted expressed sequence, Reporter |
|
•
•
•
•
•
|
| Allele |
| Name: |
transgenic transposon concatemer, Rui Benedito |
| Allele Type: |
Transgenic |
| Attribute String: |
Conditional ready, Epitope tag, Inserted expressed sequence, Reporter, Transposon concatemer |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Tg(ACTB-NOTCH1)1Shn/? Tg(Nes-cre)1Kln/? Trp53/Trp53 |
| Background: |
involves: 129S2/SvPas * C57BL/6J |
| Zygosity: |
cn |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Tg(ACTB-NOTCH1)1Shn/? Tg(Nes-cre)1Kln/? Trp53/Trp53<+> |
| Background: |
involves: 129S2/SvPas * C57BL/6J |
| Zygosity: |
cn |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Notch1/Notch1<+> Notch4/Notch4 |
| Background: |
involves: 129S1/Sv * C57BL/6 |
| Zygosity: |
cx |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Notch1/Notch1 Notch4/Notch4 |
| Background: |
involves: 129S1/Sv * C57BL/6 |
| Zygosity: |
cx |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Hes1/Hes1 Tg(Mx1-cre)1Cgn/? |
| Background: |
involves: 129S4/SvJaeSor * C57BL/6 * CBA |
| Zygosity: |
cn |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Notch4/Notch4 |
| Background: |
involves: 129S1/Sv * C57BL/6J |
| Zygosity: |
hm |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Notch4/Notch4<+> |
| Background: |
involves: 129S1/Sv * C57BL/6J |
| Zygosity: |
ht |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Adipoq-cre)1Evdr/? |
| Background: |
involves: 129S4/SvJaeSor * C57BL/6J * FVB/NJ |
| Zygosity: |
cn |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Notch4/Notch4 |
| Background: |
involves: 129S1/Sv |
| Zygosity: |
hm |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Notch4/Notch4 |
| Background: |
B6;129S1-Notch4/J |
| Zygosity: |
hm |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
921
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kuo CT |
| Year: |
2006 |
| Journal: |
Cell |
| Title: |
Postnatal deletion of Numb/Numblike reveals repair and remodeling capacity in the subventricular neurogenic niche. |
| Volume: |
127 |
| Issue: |
6 |
| Pages: |
1253-64 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kong JH |
| Year: |
2015 |
| Journal: |
Dev Cell |
| Title: |
Notch activity modulates the responsiveness of neural progenitors to sonic hedgehog signaling. |
| Volume: |
33 |
| Issue: |
4 |
| Pages: |
373-87 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mukherjee M |
| Year: |
2020 |
| Journal: |
Dev Biol |
| Title: |
Foxi1 inactivation rescues loss of principal cell fate selection in Hes1-deficient kidneys but does not ensure maintenance of principal cell gene expression. |
| Volume: |
466 |
| Issue: |
1-2 |
| Pages: |
1-11 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Le TT |
| Year: |
2012 |
| Journal: |
Dev Dyn |
| Title: |
Requirements for Jag1-Rbpj mediated Notch signaling during early mouse lens development. |
| Volume: |
241 |
| Issue: |
3 |
| Pages: |
493-504 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Surzenko N |
| Year: |
2013 |
| Journal: |
Development |
| Title: |
SOX2 maintains the quiescent progenitor cell state of postnatal retinal Muller glia. |
| Volume: |
140 |
| Issue: |
7 |
| Pages: |
1445-56 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Jadhav AP |
| Year: |
2006 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Notch activity permits retinal cells to progress through multiple progenitor states and acquire a stem cell property. |
| Volume: |
103 |
| Issue: |
50 |
| Pages: |
18998-9003 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Sekiya S |
| Year: |
2014 |
| Journal: |
Am J Pathol |
| Title: |
Hepatocytes, rather than cholangiocytes, can be the major source of primitive ductules in the chronically injured mouse liver. |
| Volume: |
184 |
| Issue: |
5 |
| Pages: |
1468-78 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mead TJ |
| Year: |
2012 |
| Journal: |
Dev Dyn |
| Title: |
Notch pathway regulation of neural crest cell development in vivo. |
| Volume: |
241 |
| Issue: |
2 |
| Pages: |
376-89 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Hosokawa S |
| Year: |
2015 |
| Journal: |
Sci Rep |
| Title: |
Impact of Sox9 dosage and Hes1-mediated Notch signaling in controlling the plasticity of adult pancreatic duct cells in mice. |
| Volume: |
5 |
|
| Pages: |
8518 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Puri RV |
| Year: |
2019 |
| Journal: |
Dis Model Mech |
| Title: |
Notch4 activation aggravates NF-κB-mediated inflammation in HIV-1-associated nephropathy. |
| Volume: |
12 |
| Issue: |
12 |
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Hartman BH |
| Year: |
2010 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Notch signaling specifies prosensory domains via lateral induction in the developing mammalian inner ear. |
| Volume: |
107 |
| Issue: |
36 |
| Pages: |
15792-7 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Ku SY |
| Year: |
2024 |
| Journal: |
J Clin Invest |
| Title: |
Notch signaling suppresses neuroendocrine differentiation and alters the immune microenvironment in advanced prostate cancer. |
| Volume: |
134 |
| Issue: |
17 |
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Fujita K |
| Year: |
2019 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Cell-autonomous FLT3L shedding via ADAM10 mediates conventional dendritic cell development in mouse spleen. |
| Volume: |
116 |
| Issue: |
29 |
| Pages: |
14714-14723 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Zhu C |
| Year: |
2018 |
| Journal: |
Sci Transl Med |
| Title: |
Hepatocyte Notch activation induces liver fibrosis in nonalcoholic steatohepatitis. |
| Volume: |
10 |
| Issue: |
468 |
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Schaffer AE |
| Year: |
2010 |
| Journal: |
Dev Cell |
| Title: |
Nkx6 transcription factors and Ptf1a function as antagonistic lineage determinants in multipotent pancreatic progenitors. |
| Volume: |
18 |
| Issue: |
6 |
| Pages: |
1022-9 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Canalis E |
| Year: |
2014 |
| Journal: |
Bone |
| Title: |
Connective tissue growth factor is a target of notch signaling in cells of the osteoblastic lineage. |
| Volume: |
64 |
|
| Pages: |
273-80 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Rock JR |
| Year: |
2011 |
| Journal: |
Cell Stem Cell |
| Title: |
Notch-dependent differentiation of adult airway basal stem cells. |
| Volume: |
8 |
| Issue: |
6 |
| Pages: |
639-48 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Chea S |
| Year: |
2016 |
| Journal: |
Sci Signal |
| Title: |
Notch signaling in group 3 innate lymphoid cells modulates their plasticity. |
| Volume: |
9 |
| Issue: |
426 |
| Pages: |
ra45 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Wohlfeil SA |
| Year: |
2019 |
| Journal: |
Cancer Res |
| Title: |
Hepatic Endothelial Notch Activation Protects against Liver Metastasis by Regulating Endothelial-Tumor Cell Adhesion Independent of Angiocrine Signaling. |
| Volume: |
79 |
| Issue: |
3 |
| Pages: |
598-610 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Cheung L |
| Year: |
2018 |
| Journal: |
Elife |
| Title: |
NOTCH activity differentially affects alternative cell fate acquisition and maintenance. |
| Volume: |
7 |
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Garcia TX |
| Year: |
2014 |
| Journal: |
Development |
| Title: |
RBPJ in mouse Sertoli cells is required for proper regulation of the testis stem cell niche. |
| Volume: |
141 |
| Issue: |
23 |
| Pages: |
4468-78 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
McKimpson WM |
| Year: |
2024 |
| Journal: |
J Cell Biol |
| Title: |
Calorie restriction activates a gastric Notch-FOXO1 pathway to expand ghrelin cells. |
| Volume: |
223 |
| Issue: |
10 |
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Souilhol C |
| Year: |
2015 |
| Journal: |
Development |
| Title: |
NOTCH activation interferes with cell fate specification in the gastrulating mouse embryo. |
| Volume: |
142 |
| Issue: |
21 |
| Pages: |
3649-60 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Tata PR |
| Year: |
2013 |
| Journal: |
Am J Respir Cell Mol Biol |
| Title: |
Airway-specific inducible transgene expression using aerosolized doxycycline. |
| Volume: |
49 |
| Issue: |
6 |
| Pages: |
1048-56 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Li L |
| Year: |
2018 |
| Journal: |
Am J Pathol |
| Title: |
Acquisition of Cholangiocarcinoma Traits during Advanced Hepatocellular Carcinoma Development in Mice. |
| Volume: |
188 |
| Issue: |
3 |
| Pages: |
656-671 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Wakabayashi N |
| Year: |
2023 |
| Journal: |
Int J Mol Sci |
| Title: |
Forced Hepatic Expression of NRF2 or NQO1 Impedes Hepatocyte Lipid Accumulation in a Lipodystrophy Mouse Model. |
| Volume: |
24 |
| Issue: |
17 |
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Ramasamy SK |
| Year: |
2016 |
| Journal: |
Nat Commun |
| Title: |
Blood flow controls bone vascular function and osteogenesis. |
| Volume: |
7 |
|
| Pages: |
13601 |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Lep/Lep Tg(Adipoq-cre)1Evdr/? |
| Background: |
involves: 129S4/SvJaeSor * C57BL/6J * FVB/NJ |
| Zygosity: |
cn |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Pten/Pten Tg(Adipoq-cre)1Evdr/? |
| Background: |
involves: 129S4/SvJae * 129S4/SvJaeSor * C57BL/6J * FVB/NJ |
| Zygosity: |
cn |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Sakaidani Y |
| Year: |
2012 |
| Journal: |
Biochem Biophys Res Commun |
| Title: |
O-linked-N-acetylglucosamine modification of mammalian Notch receptors by an atypical O-GlcNAc transferase Eogt1. |
| Volume: |
419 |
| Issue: |
1 |
| Pages: |
14-9 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Braune EB |
| Year: |
2014 |
| Journal: |
Mol Cell Biol |
| Title: |
S/T phosphorylation of DLL1 is required for full ligand activity in vitro but dispensable for DLL1 function in vivo during embryonic patterning and marginal zone B cell development. |
| Volume: |
34 |
| Issue: |
7 |
| Pages: |
1221-33 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Gao N |
| Year: |
2005 |
| Journal: |
Development |
| Title: |
Forkhead box A1 regulates prostate ductal morphogenesis and promotes epithelial cell maturation. |
| Volume: |
132 |
| Issue: |
15 |
| Pages: |
3431-43 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Li T |
| Year: |
2003 |
| Journal: |
J Neurosci |
| Title: |
Nicastrin is required for assembly of presenilin/gamma-secretase complexes to mediate Notch signaling and for processing and trafficking of beta-amyloid precursor protein in mammals. |
| Volume: |
23 |
| Issue: |
8 |
| Pages: |
3272-7 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
An JY |
| Year: |
2006 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Impaired neurogenesis and cardiovascular development in mice lacking the E3 ubiquitin ligases UBR1 and UBR2 of the N-end rule pathway. |
| Volume: |
103 |
| Issue: |
16 |
| Pages: |
6212-7 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Aruga J |
| Year: |
2002 |
| Journal: |
Dev Biol |
| Title: |
Zic1 promotes the expansion of dorsal neural progenitors in spinal cord by inhibiting neuronal differentiation. |
| Volume: |
244 |
| Issue: |
2 |
| Pages: |
329-41 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Ballester-López C |
| Year: |
2019 |
| Journal: |
EBioMedicine |
| Title: |
The Notch ligand DNER regulates macrophage IFNγ release in chronic obstructive pulmonary disease. |
| Volume: |
43 |
|
| Pages: |
562-575 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Arumugam A |
| Year: |
2014 |
| Journal: |
Biochem Biophys Res Commun |
| Title: |
Keratin-6 driven ODC expression to hair follicle keratinocytes enhances stemness and tumorigenesis by negatively regulating Notch. |
| Volume: |
451 |
| Issue: |
3 |
| Pages: |
394-401 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Ghezzo MN |
| Year: |
2018 |
| Journal: |
Carcinogenesis |
| Title: |
FoxN1-dependent thymic epithelial cells promote T-cell leukemia development. |
| Volume: |
39 |
| Issue: |
12 |
| Pages: |
1463-1476 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Martz CA |
| Year: |
2014 |
| Journal: |
Sci Signal |
| Title: |
Systematic identification of signaling pathways with potential to confer anticancer drug resistance. |
| Volume: |
7 |
| Issue: |
357 |
| Pages: |
ra121 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Nueda ML |
| Year: |
2014 |
| Journal: |
Biochim Biophys Acta |
| Title: |
The proteins DLK1 and DLK2 modulate NOTCH1-dependent proliferation and oncogenic potential of human SK-MEL-2 melanoma cells. |
| Volume: |
1843 |
| Issue: |
11 |
| Pages: |
2674-84 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Chandrasekaran B |
| Year: |
2018 |
| Journal: |
Carcinogenesis |
| Title: |
The chemopreventive effect of withaferin A on spontaneous and inflammation-associated colon carcinogenesis models. |
| Volume: |
39 |
| Issue: |
12 |
| Pages: |
1537-1547 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Rodilla V |
| Year: |
2009 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Jagged1 is the pathological link between Wnt and Notch pathways in colorectal cancer. |
| Volume: |
106 |
| Issue: |
15 |
| Pages: |
6315-20 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Guilmeau S |
| Year: |
2010 |
| Journal: |
Oncogene |
| Title: |
Heterogeneity of Jagged1 expression in human and mouse intestinal tumors: implications for targeting Notch signaling. |
| Volume: |
29 |
| Issue: |
7 |
| Pages: |
992-1002 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Guo W |
| Year: |
2008 |
| Journal: |
Nature |
| Title: |
Multi-genetic events collaboratively contribute to Pten-null leukaemia stem-cell formation. |
| Volume: |
453 |
| Issue: |
7194 |
| Pages: |
529-33 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Takahashi K |
| Year: |
2007 |
| Journal: |
Oncogene |
| Title: |
Ablation of a peptidyl prolyl isomerase Pin1 from p53-null mice accelerated thymic hyperplasia by increasing the level of the intracellular form of Notch1. |
| Volume: |
26 |
| Issue: |
26 |
| Pages: |
3835-45 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Yan H |
| Year: |
2010 |
| Journal: |
Am J Pathol |
| Title: |
Pathways contributing to development of spontaneous mammary tumors in BALB/c-Trp53+/- mice. |
| Volume: |
176 |
| Issue: |
3 |
| Pages: |
1421-32 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Pancewicz J |
| Year: |
2010 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Notch signaling contributes to proliferation and tumor formation of human T-cell leukemia virus type 1-associated adult T-cell leukemia. |
| Volume: |
107 |
| Issue: |
38 |
| Pages: |
16619-24 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Nus M |
| Year: |
2016 |
| Journal: |
Cardiovasc Res |
| Title: |
Endothelial Jag1-RBPJ signalling promotes inflammatory leucocyte recruitment and atherosclerosis. |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Yang F |
| Year: |
2020 |
| Journal: |
Cardiovasc Res |
| Title: |
Macrophage-derived MMP-8 determines smooth muscle cell differentiation from adventitia stem/progenitor cells and promotes neointima hyperplasia. |
| Volume: |
116 |
| Issue: |
1 |
| Pages: |
211-225 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Trujillo CA |
| Year: |
2012 |
| Journal: |
J Biol Chem |
| Title: |
Kinin-B2 receptor activity determines the differentiation fate of neural stem cells. |
| Volume: |
287 |
| Issue: |
53 |
| Pages: |
44046-61 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Okamoto M |
| Year: |
2008 |
| Journal: |
J Exp Med |
| Title: |
Essential role of Notch signaling in effector memory CD8+ T cell-mediated airway hyperresponsiveness and inflammation. |
| Volume: |
205 |
| Issue: |
5 |
| Pages: |
1087-97 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Jena N |
| Year: |
2016 |
| Journal: |
Leukemia |
| Title: |
CDK6-mediated repression of CD25 is required for induction and maintenance of Notch1-induced T-cell acute lymphoblastic leukemia. |
| Volume: |
30 |
| Issue: |
5 |
| Pages: |
1033-43 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Burghardt S |
| Year: |
2013 |
| Journal: |
J Immunol |
| Title: |
Hepatocytes contribute to immune regulation in the liver by activation of the Notch signaling pathway in T cells. |
| Volume: |
191 |
| Issue: |
11 |
| Pages: |
5574-82 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kang X |
| Year: |
2016 |
| Journal: |
Sci Rep |
| Title: |
Nox2 contributes to the arterial endothelial specification of mouse induced pluripotent stem cells by upregulating Notch signaling. |
| Volume: |
6 |
|
| Pages: |
33737 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mazzieri R |
| Year: |
2015 |
| Journal: |
Cancer Res |
| Title: |
Urokinase Receptor Promotes Skin Tumor Formation by Preventing Epithelial Cell Activation of Notch1. |
| Volume: |
75 |
| Issue: |
22 |
| Pages: |
4895-909 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Tremblay M |
| Year: |
2010 |
| Journal: |
Genes Dev |
| Title: |
Modeling T-cell acute lymphoblastic leukemia induced by the SCL and LMO1 oncogenes. |
| Volume: |
24 |
| Issue: |
11 |
| Pages: |
1093-105 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Costa RM |
| Year: |
2003 |
| Journal: |
Curr Biol |
| Title: |
Learning and memory deficits in Notch mutant mice. |
| Volume: |
13 |
| Issue: |
15 |
| Pages: |
1348-54 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Lu R |
| Year: |
2014 |
| Journal: |
PLoS One |
| Title: |
Parathyroid hormone administration improves bone marrow microenvironment and partially rescues haematopoietic defects in Bmi1-null mice. |
| Volume: |
9 |
| Issue: |
4 |
| Pages: |
e93864 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Cerqueira DM |
| Year: |
2019 |
| Journal: |
Am J Physiol Renal Physiol |
| Title: |
In utero exposure to maternal diabetes impairs nephron progenitor differentiation. |
| Volume: |
317 |
| Issue: |
5 |
| Pages: |
F1318-F1330 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Högström J |
| Year: |
2018 |
| Journal: |
Cancer Res |
| Title: |
Transcription Factor PROX1 Suppresses Notch Pathway Activation via the Nucleosome Remodeling and Deacetylase Complex in Colorectal Cancer Stem-like Cells. |
| Volume: |
78 |
| Issue: |
20 |
| Pages: |
5820-5832 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Witkowski MT |
| Year: |
2015 |
| Journal: |
Leukemia |
| Title: |
Activated Notch counteracts Ikaros tumor suppression in mouse and human T-cell acute lymphoblastic leukemia. |
| Volume: |
29 |
| Issue: |
6 |
| Pages: |
1301-11 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Lee HO |
| Year: |
2015 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Disregulated expression of the transcription factor ThPOK during T-cell development leads to high incidence of T-cell lymphomas. |
| Volume: |
112 |
| Issue: |
25 |
| Pages: |
7773-8 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Lucitti JL |
| Year: |
2012 |
| Journal: |
Circ Res |
| Title: |
Formation of the collateral circulation is regulated by vascular endothelial growth factor-A and a disintegrin and metalloprotease family members 10 and 17. |
| Volume: |
111 |
| Issue: |
12 |
| Pages: |
1539-50 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Cioffi S |
| Year: |
2014 |
| Journal: |
Hum Mol Genet |
| Title: |
Tbx1 regulates brain vascularization. |
| Volume: |
23 |
| Issue: |
1 |
| Pages: |
78-89 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Zhang C |
| Year: |
2015 |
| Journal: |
Glia |
| Title: |
MicroRNA-mediated non-cell-autonomous regulation of cortical radial glial transformation revealed by a Dicer1 knockout mouse model. |
| Volume: |
63 |
| Issue: |
5 |
| Pages: |
860-76 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Bhoumik A |
| Year: |
2008 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Suppressor role of activating transcription factor 2 (ATF2) in skin cancer. |
| Volume: |
105 |
| Issue: |
5 |
| Pages: |
1674-9 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Ungerbäck J |
| Year: |
2015 |
| Journal: |
J Exp Med |
| Title: |
Combined heterozygous loss of Ebf1 and Pax5 allows for T-lineage conversion of B cell progenitors. |
| Volume: |
212 |
| Issue: |
7 |
| Pages: |
1109-23 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Tiemessen MM |
| Year: |
2012 |
| Journal: |
PLoS Biol |
| Title: |
The nuclear effector of Wnt-signaling, Tcf1, functions as a T-cell-specific tumor suppressor for development of lymphomas. |
| Volume: |
10 |
| Issue: |
11 |
| Pages: |
e1001430 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Treanor LM |
| Year: |
2014 |
| Journal: |
J Exp Med |
| Title: |
Interleukin-7 receptor mutants initiate early T cell precursor leukemia in murine thymocyte progenitors with multipotent potential. |
| Volume: |
211 |
| Issue: |
4 |
| Pages: |
701-13 |
|
•
•
•
•
•
|