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Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: human
Publication
First Author: Sharma A
Year: 2010
Journal: PLoS One
Title: Hepatic gene expression profiling reveals key pathways involved in leptin-mediated weight loss in ob/ob mice.
Volume: 5
Issue: 8
Pages: e12147
Genotype
Symbol: a/a Mlph/Mlph
Background: Not Specified
Zygosity: cx
Has Mutant Allele: true
Publication
First Author: Banga A
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: In vivo reprogramming of Sox9+ cells in the liver to insulin-secreting ducts.
Volume: 109
Issue: 38
Pages: 15336-41
Publication
First Author: Nonaka M
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Synthetic di-sulfated iduronic acid attenuates asthmatic response by blocking T-cell recruitment to inflammatory sites.
Volume: 111
Issue: 22
Pages: 8173-8
Publication
First Author: Sengupta A
Year: 2019
Journal: Neuron
Title: A Discrete Dorsal Raphe to Basal Amygdala 5-HT Circuit Calibrates Aversive Memory.
Volume: 103
Issue: 3
Pages: 489-505.e7
Publication
First Author: Rongvaux A
Year: 2014
Journal: Cell
Title: Apoptotic caspases prevent the induction of type I interferons by mitochondrial DNA.
Volume: 159
Issue: 7
Pages: 1563-77
Publication
First Author: Gegonne A
Year: 2001
Journal: Proc Natl Acad Sci U S A
Title: TAFII55 binding to TAFII250 inhibits its acetyltransferase activity.
Volume: 98
Issue: 22
Pages: 12432-7
Publication
First Author: Muhammad A
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: Retromer deficiency observed in Alzheimer's disease causes hippocampal dysfunction, neurodegeneration, and Abeta accumulation.
Volume: 105
Issue: 20
Pages: 7327-32
MP Term
MP Term
Publication
First Author: Zhang H
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: Genetic rescue of lineage-balanced blood cell production reveals a crucial role for STAT3 antiinflammatory activity in hematopoiesis.
Volume: 115
Issue: 10
Pages: E2311-E2319
Publication
First Author: Jonkers J
Year: 1997
Journal: EMBO J
Title: Activation of a novel proto-oncogene, Frat1, contributes to progression of mouse T-cell lymphomas.
Volume: 16
Issue: 3
Pages: 441-50
Publication
First Author: Zembrzycki A
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: Postmitotic regulation of sensory area patterning in the mammalian neocortex by Lhx2.
Volume: 112
Issue: 21
Pages: 6736-41
Publication
First Author: Kazantsev A
Year: 1999
Journal: Proc Natl Acad Sci U S A
Title: Insoluble detergent-resistant aggregates form between pathological and nonpathological lengths of polyglutamine in mammalian cells.
Volume: 96
Issue: 20
Pages: 11404-9
Publication
First Author: Larder R
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: Obesity-associated gene TMEM18 has a role in the central control of appetite and body weight regulation.
Volume: 114
Issue: 35
Pages: 9421-9426
Publication
First Author: de Beer MC
Year: 1993
Journal: J Biol Chem
Title: Structural prerequisites for serum amyloid A fibril formation.
Volume: 268
Issue: 27
Pages: 20606-12
GXD Expression      
Probe: MGI:1194599
Assay Type: Northern blot
Annotation Date: 2011-07-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3577328
Stage: TS28
Assay Id: MGI:5014787
Age: postnatal adult
Specimen Label: Muscle A
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:1194599
Assay Type: Northern blot
Annotation Date: 2011-07-18
Strength: Present
Sex: Female
Emaps: EMAPS:1796228
Stage: TS28
Assay Id: MGI:5014787
Age: postnatal adult
Specimen Label: Ovary A
Detected: true
Specimen Num: 7
GXD Expression      
Probe: MGI:1194599
Assay Type: Northern blot
Annotation Date: 2011-07-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:5014787
Age: postnatal adult
Specimen Label: Liver A
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:1194599
Assay Type: Northern blot
Annotation Date: 2011-07-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:5014787
Age: postnatal adult
Specimen Label: Kidney A
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:1194599
Assay Type: Northern blot
Annotation Date: 2011-07-18
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:5014787
Age: postnatal adult
Specimen Label: Testis A
Detected: true
Specimen Num: 9
Publication
First Author: Kubo Y
Year: 2005
Journal: Mol Cell Biol
Title: ABCA5 resides in lysosomes, and ABCA5 knockout mice develop lysosomal disease-like symptoms.
Volume: 25
Issue: 10
Pages: 4138-49
Strain
Attribute String: mutant stock, radiation induced mutation, spontaneous mutation
Publication
First Author: Chen SS
Year: 2000
Journal: Mol Cell Biol
Title: C/EBPbeta, when expressed from the C/ebpalpha gene locus, can functionally replace C/EBPalpha in liver but not in adipose tissue.
Volume: 20
Issue: 19
Pages: 7292-9
Publication
First Author: Floyd JA
Year: 2003
Journal: Nat Genet
Title: A natural allele of Nxf1 suppresses retrovirus insertional mutations.
Volume: 35
Issue: 3
Pages: 221-8
Chromosome Structure Variation
Type: chromosomal_transposition
Organism: mouse, laboratory
Genotype
Symbol: A/a
Background: C57BL/6NTac-A/a
Zygosity: ht
Has Mutant Allele: true
Publication
First Author: Vanhoutteghem A
Year: 2004
Journal: Proc Natl Acad Sci U S A
Title: Basonuclin 2: an extremely conserved homolog of the zinc finger protein basonuclin.
Volume: 101
Issue: 10
Pages: 3468-73
Publication
First Author: Hogmalm A
Year: 2018
Journal: Am J Physiol Lung Cell Mol Physiol
Title: Pulmonary IL-1β expression in early life causes permanent changes in lung structure and function in adulthood.
Volume: 314
Issue: 6
Pages: L936-L945
Publication
First Author: Gams A
Year: 2023
Journal: Physiol Rep
Title: Evidence of sex differences in cancer-related cardiac complications in mouse models of pancreatic and liver cancer.
Volume: 11
Issue: 8
Pages: e15672
Other Genome Feature
Type: sequence_feature
Organism: mouse, laboratory
Other Genome Feature
Type: sequence_feature
Organism: mouse, laboratory
Publication
First Author: Vidal-Puig A
Year: 1996
Journal: J Clin Invest
Title: Regulation of PPAR gamma gene expression by nutrition and obesity in rodents.
Volume: 97
Issue: 11
Pages: 2553-61
Publication  
First Author: ten Berg R
Year: 1989
Journal: Mouse News Lett
Title: SD patterns of a series of OXA recombinant inbred strains
Volume: 84
Pages: 102-104
Transgene
Type: transgene
Organism: mouse, laboratory
Publication
First Author: Silva A
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: NF-κB signaling mediates homeostatic maturation of new T cells.
Volume: 111
Issue: 9
Pages: E846-55
Transgene
Type: transgene
Organism: mouse, laboratory
Publication
First Author: Khanna A
Year: 2015
Journal: Cancer Res
Title: DNA damage in cancer therapeutics: a boon or a curse?
Volume: 75
Issue: 11
Pages: 2133-8
Publication
First Author: Segal-Lieberman G
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Melanin-concentrating hormone is a critical mediator of the leptin-deficient phenotype.
Volume: 100
Issue: 17
Pages: 10085-90
Publication  
First Author: Hernandez-Gutierrez A
Year: 2023
Journal: J Clin Invest
Title: Phospholipid scramblase-1 regulates innate type 2 inflammation in mouse lungs via CRTH2-dependent mechanisms.
Volume: 133
Issue: 15
Publication
First Author: Bigi A
Year: 2016
Journal: Oncogene
Title: Cyclophilin D counteracts P53-mediated growth arrest and promotes Ras tumorigenesis.
Volume: 35
Issue: 39
Pages: 5132-43
Publication
First Author: Vanhoutteghem A
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: Basonuclin 2 has a function in the multiplication of embryonic craniofacial mesenchymal cells and is orthologous to disco proteins.
Volume: 106
Issue: 34
Pages: 14432-7
Publication
First Author: Ward A
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: Flexibility in the ABC transporter MsbA: Alternating access with a twist.
Volume: 104
Issue: 48
Pages: 19005-10
Publication
First Author: Mori A
Year: 2006
Journal: Int J Cancer
Title: Severe pulmonary metastasis in obese and diabetic mice.
Volume: 119
Issue: 12
Pages: 2760-7
Publication
First Author: Batra A
Year: 2007
Journal: Am J Pathol
Title: Leptin-dependent toll-like receptor expression and responsiveness in preadipocytes and adipocytes.
Volume: 170
Issue: 6
Pages: 1931-41
Publication
First Author: Shemesh A
Year: 2014
Journal: PLoS One
Title: The antidepressant trans-2-phenylcyclopropylamine protects mice from high-fat-diet-induced obesity.
Volume: 9
Issue: 2
Pages: e89199
Publication  
First Author: De Iaco A
Year: 2020
Journal: Development
Title: DUX is a non-essential synchronizer of zygotic genome activation.
Volume: 147
Issue: 2
Publication
First Author: Samanta A
Year: 1995
Journal: Proc Natl Acad Sci U S A
Title: A kinase associated with chromatin that can be activated by ligand-p185c-Neu or epidermal growth factor-receptor interactions.
Volume: 92
Issue: 14
Pages: 6582-6
Publication
First Author: Kurima K
Year: 1998
Journal: Proc Natl Acad Sci U S A
Title: A member of a family of sulfate-activating enzymes causes murine brachymorphism.
Volume: 95
Issue: 15
Pages: 8681-5
Publication
First Author: Hsu MY
Year: 1990
Journal: Proc Natl Acad Sci U S A
Title: Retron for the 67-base multicopy single-stranded DNA from Escherichia coli: a potential transposable element encoding both reverse transcriptase and Dam methylase functions.
Volume: 87
Issue: 23
Pages: 9454-8
Publication
First Author: Cartier A
Year: 2020
Journal: Proc Natl Acad Sci U S A
Title: Endothelial sphingosine 1-phosphate receptors promote vascular normalization and antitumor therapy.
Volume: 117
Issue: 6
Pages: 3157-3166
Publication
First Author: Sasaki T
Year: 1993
Journal: Zoolog Sci
Title: Mouse gamma-casein cDNA: PCR cloning and sequence analysis.
Volume: 10
Issue: 1
Pages: 65-72
Publication
First Author: Carey C
Year: 2022
Journal: Transl Psychiatry
Title: From bench to bedside: The mGluR5 system in people with and without Autism Spectrum Disorder and animal model systems.
Volume: 12
Issue: 1
Pages: 395
Publication
First Author: Huff A
Year: 2022
Journal: Proc Natl Acad Sci U S A
Title: Optogenetic stimulation of pre-Bötzinger complex reveals novel circuit interactions in swallowing-breathing coordination.
Volume: 119
Issue: 29
Pages: e2121095119
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication
First Author: Ushio A
Year: 2024
Journal: Cell Rep
Title: Functionally diverse thymic medullary epithelial cells interplay to direct central tolerance.
Volume: 43
Issue: 4
Pages: 114072