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Search results 3901 to 4000 out of 4306 for C3

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Type Details Score
Publication
30185466 | J:266101
First Author: Acharjee S
Year: 2018
Journal: J Neurosci
Title: Reduced Microglial Activity and Enhanced Glutamate Transmission in the Basolateral Amygdala in Early CNS Autoimmunity.
Volume: 38
Issue: 42
Pages: 9019-9033
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Publication
25106095 | J:320889
 
First Author: Zhao X
Year: 2014
Journal: J Mol Cell Cardiol
Title: Induction of the matricellular protein CCN1 through RhoA and MRTF-A contributes to ischemic cardioprotection.
Volume: 75
Pages: 152-61
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Publication
8419166 | J:3700
First Author: Hellman L
Year: 1993
Journal: Eur J Immunol
Title: Characterization of four novel epsilon chain mRNA and a comparative analysis of genes for immunoglobulin E in rodents and man.
Volume: 23
Issue: 1
Pages: 159-67
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Publication
8513597 | J:12778
First Author: Hultman P
Year: 1993
Journal: Clin Immunol Immunopathol
Title: Murine susceptibility to mercury. II. autoantibody profiles and renal immune deposits in hybrid, backcross, and H-2d congenic mice.
Volume: 68
Issue: 1
Pages: 9-20
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Publication
8649451 | J:33481
First Author: Ebanks RO
Year: 1996
Journal: Mol Immunol
Title: Mouse complement component C4 is devoid of classical pathway C5 convertase subunit activity.
Volume: 33
Issue: 3
Pages: 297-309
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Publication
9708821 | J:49106
First Author: Murray AG
Year: 1998
Journal: Am J Pathol
Title: Dermal microvascular injury in the human peripheral blood lymphocyte reconstituted-severe combined immunodeficient (HuPBL-SCID) mouse/skin allograft model is T cell mediated and inhibited by a combination of cyclosporine and rapamycin.
Volume: 153
Issue: 2
Pages: 627-38
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Publication
10027923 | J:53788
First Author: Kamata T
Year: 1999
Journal: Kidney Int
Title: Up-regulation of glomerular extracellular matrix and transforming growth factor-beta expression in RF/J mice.
Volume: 55
Issue: 3
Pages: 864-76
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Publication
18255094 | J:133927
First Author: Samarakoon R
Year: 2008
Journal: J Mol Cell Cardiol
Title: TGF-beta1-induced plasminogen activator inhibitor-1 expression in vascular smooth muscle cells requires pp60(c-src)/EGFR(Y845) and Rho/ROCK signaling.
Volume: 44
Issue: 3
Pages: 527-38
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Publication
29437855 | J:262535
     
First Author: Alawieh A
Year: 2018
Journal: J Neurosci
Title: Identifying the role of complement in triggering neuroinflammation after traumatic brain injury.
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Publication
30453990 | J:295585
First Author: Yamanishi K
Year: 2018
Journal: J Transl Med
Title: Deficiency in interleukin-18 promotes differentiation of brown adipose tissue resulting in fat accumulation despite dyslipidemia.
Volume: 16
Issue: 1
Pages: 314
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Publication
7710686 | J:24539
First Author: Bedford M
Year: 1995
Journal: DNA Cell Biol
Title: Analysis of the Hoxd-3 gene: structure and localization of its sense and natural antisense transcripts.
Volume: 14
Issue: 4
Pages: 295-304
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Publication
16328467 | J:194457
First Author: Endo Y
Year: 2005
Journal: Immunogenetics
Title: Carbohydrate-binding specificities of mouse ficolin A, a splicing variant of ficolin A and ficolin B and their complex formation with MASP-2 and sMAP.
Volume: 57
Issue: 11
Pages: 837-44
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Publication
10926763 | J:64019
First Author: Bel-Vialar S
Year: 2000
Journal: Dev Biol
Title: Altered retinoic acid sensitivity and temporal expression of Hox genes in polycomb-M33-deficient mice.
Volume: 224
Issue: 2
Pages: 238-49
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Publication
27088797 | J:234934
First Author: Farrar CA
Year: 2016
Journal: J Clin Invest
Title: Collectin-11 detects stress-induced L-fucose pattern to trigger renal epithelial injury.
Volume: 126
Issue: 5
Pages: 1911-25
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Publication
26149093 | J:230770
 
First Author: Yu M
Year: 2015
Journal: Exp Eye Res
Title: Deficiency of CC chemokine ligand 2 and decay-accelerating factor causes retinal degeneration in mice.
Volume: 138
Pages: 126-33
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Publication
31869396 | J:292499
First Author: Bibert S
Year: 2019
Journal: PLoS Pathog
Title: Herpes simplex encephalitis in adult patients with MASP-2 deficiency.
Volume: 15
Issue: 12
Pages: e1008168
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Publication
24740308 | J:215201
First Author: Dib S
Year: 2014
Journal: PLoS One
Title: Gene targeting of mouse Tardbp negatively affects Masp2 expression.
Volume: 9
Issue: 4
Pages: e95373
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Publication
1973141 | J:10597
First Author: Stubbs L
Year: 1990
Journal: Genomics
Title: The murine genes Hox-5.1 and Hox-4.1 belong to the same HOX complex on chromosome 2.
Volume: 7
Issue: 3
Pages: 422-7
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Publication
15340071 | J:92772
First Author: Rastegar M
Year: 2004
Journal: Mol Cell Biol
Title: Sequential histone modifications at Hoxd4 regulatory regions distinguish anterior from posterior embryonic compartments.
Volume: 24
Issue: 18
Pages: 8090-103
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Publication
17010333 | J:115152
First Author: Nolte C
Year: 2006
Journal: Dev Biol
Title: Stereospecificity and PAX6 function direct Hoxd4 neural enhancer activity along the antero-posterior axis.
Volume: 299
Issue: 2
Pages: 582-93
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Strain
MGI:2159747 | A/J
Attribute String: inbred strain
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Publication
23341629 | J:193822
First Author: Lumayag S
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Inactivation of the microRNA-183/96/182 cluster results in syndromic retinal degeneration.
Volume: 110
Issue: 6
Pages: E507-16
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Protein Coding Gene
MGI:98898 | Ugt1a1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:95706 | Ggt1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:104767 | Gpx4
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1333812 | Mbd3
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1860292 | Ramp3
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:98328 | Sstr2
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:95720 | Gjb2
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:95708 | Ghr
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1315213 | Nrip1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1333813 | Mbd2
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1261433 | Endog
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:2446977 | Kif18a
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1926321 | Postn
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:107474 | Cd38
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1340094 | Cxcl2
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:88068 | Areg
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:95797 | Gpi1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:109325 | F7
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:108085 | Hpgd
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:88587 | Cyp19a1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein
Q6GQT1
Organism: Mus musculus/domesticus
Length: 1474  
Fragment?: false
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Protein
Q61838
Organism: Mus musculus/domesticus
Length: 1495  
Fragment?: false
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Protein
P28666
Organism: Mus musculus/domesticus
Length: 1451  
Fragment?: false
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Protein
Q3UU35
Organism: Mus musculus/domesticus
Length: 1456  
Fragment?: false
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Protein
P28665
Organism: Mus musculus/domesticus
Length: 1476  
Fragment?: false
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Protein
A0A0N4SVU1
Organism: Mus musculus/domesticus
Length: 1476  
Fragment?: false
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Protein
Q8BNV3
Organism: Mus musculus/domesticus
Length: 742  
Fragment?: true
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Publication
34970276 | -
 
First Author: Vandooren J
Year: 2021
Journal: Front Immunol
Title: Alpha-2-Macroglobulin in Inflammation, Immunity and Infections.
Volume: 12
Pages: 803244
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Publication
28705898 | J:243411
First Author: Rutledge EA
Year: 2017
Journal: Development
Title: Cellular heterogeneity in the ureteric progenitor niche and distinct profiles of branching morphogenesis in organ development.
Volume: 144
Issue: 17
Pages: 3177-3188
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Publication
- | J:66661
       
First Author: National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health
Year: 2001
Title: GenBank Record Derived Information
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Publication
30355617 | J:269896
First Author: Fan X
Year: 2018
Journal: J Exp Med
Title: CD49b defines functionally mature Treg cells that survey skin and vascular tissues.
Volume: 215
Issue: 11
Pages: 2796-2814
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Publication
17493263 | J:160877
First Author: Herschkowitz JI
Year: 2007
Journal: Genome Biol
Title: Identification of conserved gene expression features between murine mammary carcinoma models and human breast tumors.
Volume: 8
Issue: 5
Pages: R76
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Publication
17804718 | J:124885
First Author: Deeb KK
Year: 2007
Journal: Cancer Res
Title: Identification of an integrated SV40 T/t-antigen cancer signature in aggressive human breast, prostate, and lung carcinomas with poor prognosis.
Volume: 67
Issue: 17
Pages: 8065-80
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Publication
23332765 | J:193498
First Author: Burd CE
Year: 2013
Journal: Cell
Title: Monitoring tumorigenesis and senescence in vivo with a p16(INK4a)-luciferase model.
Volume: 152
Issue: 1-2
Pages: 340-51
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Publication
35121987 | J:321212
First Author: Shen M
Year: 2022
Journal: Nat Cancer
Title: Small-molecule inhibitors that disrupt the MTDH-SND1 complex suppress breast cancer progression and metastasis.
Volume: 3
Issue: 1
Pages: 43-59
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Publication
10713680 | J:61035
First Author: Cardiff RD
Year: 2000
Journal: Oncogene
Title: The mammary pathology of genetically engineered mice: the consensus report and recommendations from the Annapolis meeting.
Volume: 19
Issue: 8
Pages: 968-88
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Publication
33120014 | J:300524
First Author: Ognjenovic NB
Year: 2020
Journal: Dev Cell
Title: Limiting Self-Renewal of the Basal Compartment by PKA Activation Induces Differentiation and Alters the Evolution of Mammary Tumors.
Volume: 55
Issue: 5
Pages: 544-557.e6
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Publication
23853545 | J:201417
First Author: Vahl JC
Year: 2013
Journal: PLoS Biol
Title: NKT cell-TCR expression activates conventional T cells in vivo, but is largely dispensable for mature NKT cell biology.
Volume: 11
Issue: 6
Pages: e1001589
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Publication
26317471 | J:224904
First Author: Arpaia N
Year: 2015
Journal: Cell
Title: A Distinct Function of Regulatory T Cells in Tissue Protection.
Volume: 162
Issue: 5
Pages: 1078-89
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Publication
38861924 | J:349941
First Author: Geels SN
Year: 2024
Journal: Cancer Cell
Title: Interruption of the intratumor CD8(+) T cell:Treg crosstalk improves the efficacy of PD-1 immunotherapy.
Volume: 42
Issue: 6
Pages: 1051-1066.e7
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Protein
P14152
Organism: Mus musculus/domesticus
Length: 334  
Fragment?: false
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Protein
P08249
Organism: Mus musculus/domesticus
Length: 338  
Fragment?: false
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Protein
A0A0J9YUU3
Organism: Mus musculus/domesticus
Length: 193  
Fragment?: true
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Protein
Q62237
Organism: Mus musculus/domesticus
Length: 141  
Fragment?: true
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Protein
Q14BD9
Organism: Mus musculus/domesticus
Length: 348  
Fragment?: false
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Protein
Q505K6
Organism: Mus musculus/domesticus
Length: 333  
Fragment?: false
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Protein
A2AS37
Organism: Mus musculus/domesticus
Length: 356  
Fragment?: false
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Protein
A0A2I3BQE1
Organism: Mus musculus/domesticus
Length: 351  
Fragment?: false
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Protein
Q8BWS8
Organism: Mus musculus/domesticus
Length: 352  
Fragment?: false
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Protein
V9GZF6
Organism: Mus musculus/domesticus
Length: 345  
Fragment?: true
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Protein
A0A0G2JF23
Organism: Mus musculus/domesticus
Length: 199  
Fragment?: true
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Protein
V9H0U1
Organism: Mus musculus/domesticus
Length: 195  
Fragment?: true
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Protein
A0A5F8MPN8
Organism: Mus musculus/domesticus
Length: 355  
Fragment?: false
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Protein
A0A2I3BRQ1
Organism: Mus musculus/domesticus
Length: 352  
Fragment?: false
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Protein
Q8BWN9
Organism: Mus musculus/domesticus
Length: 348  
Fragment?: false
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Publication
9460917 | -
 
First Author: Zoll J
Year: 1998
Journal: J Gen Virol
Title: Genetic analysis of mengovirus protein 2A: its function in polyprotein processing and virus reproduction.
Volume: 79 ( Pt 1)
Pages: 17-25
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Publication
8164744 | -
First Author: Allaire M
Year: 1994
Journal: Nature
Title: Picornaviral 3C cysteine proteinases have a fold similar to chymotrypsin-like serine proteinases.
Volume: 369
Issue: 6475
Pages: 72-6
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Protein Domain
IPR000081 | Peptidase_C3
Type: Domain
Description: This domain defines cysteine peptidases belong to MEROPS peptidase family C3 (picornain, clan PA(C)), subfamilies 3CA and 3CB. The protein fold of this peptidase domain for members of this family resembles that of the serine peptidase, chymotrypsin [], the type example for clan PA.Picornaviral proteins are expressed as a single polyproteinwhich is cleaved by the viral 3C cysteine protease []. The poliovirus polyprotein is selectively cleaved between the Gln-|-Gly bond. In other picornavirus reactions Glu may be substituted for Gln, and Ser or Thr for Gly.A cysteine peptidase is a proteolytic enzyme that hydrolyses a peptide bond using the thiol group of a cysteine residue as a nucleophile. Hydrolysis involves usually a catalytic triad consisting of the thiol group of the cysteine, the imidazolium ring of a histidine, and a third residue, usually asparagine or aspartic acid, to orientate and activate the imidazolium ring. In only one family of cysteine peptidases, is the role of the general base assigned to a residue other than a histidine: in peptidases from family C89 (acid ceramidase) an arginine is the general base. Cysteine peptidases can be grouped into fourteen different clans, with members of each clan possessing a tertiary fold unique to the clan. Four clans of cysteine peptidases share structural similarities with serine and threonine peptidases and asparagine lyases. From sequence similarities, cysteine peptidases can be clustered into over 80 different families []. Clans CF, CM, CN, CO, CP and PD contain only one family.Cysteine peptidases are often active at acidic pH and are therefore confined to acidic environments, such as the animal lysosome or plant vacuole. Cysteine peptidases can be endopeptidases, aminopeptidases, carboxypeptidases, dipeptidyl-peptidases or omega-peptidases. They are inhibited by thiol chelators such as iodoacetate, iodoacetic acid, N-ethylmaleimide or p-chloromercuribenzoate.Clan CA includes proteins with a papain-like fold. There is a catalytic triad which occurs in the order: Cys/His/Asn (or Asp). A fourth residue, usually Gln, is important for stabilising the acyl intermediate that forms during catalysis, and this precedes the active site Cys. The fold consists of two subdomains with the active site between them. One subdomain consists of a bundle of helices, with the catalytic Cys at the end of one of them, and the other subdomain is a β-barrel with the active site His and Asn (or Asp). There are over thirty families in the clan, and tertiary structures have been solved for members of most of these. Peptidases in clan CA are usually sensitive to the small molecule inhibitor E64, which is ineffective against peptidases from other clans of cysteine peptidases [].Clan CD includes proteins with a caspase-like fold. Proteins in the clan have an α/β/α sandwich structure. There is a catalytic dyad which occurs in the order His/Cys. The active site His occurs in a His-Gly motif and the active site Cys occurs in an Ala-Cys motif; both motifs are preceded by a block of hydrophobic residues []. Specificity is predominantly directed towards residues that occupy the S1 binding pocket, so that caspases cleave aspartyl bonds, legumains cleave asparaginyl bonds, and gingipains cleave lysyl or arginyl bonds.Clan CE includes proteins with an adenain-like fold. The fold consists of two subdomains with the active site between them. One domain is a bundle of helices, and the other a β-barrell. The subdomains are in the opposite order to those found in peptidases from clan CA, and this is reflected in the order of active site residues: His/Asn/Gln/Cys. This has prompted speculation that proteins in clans CA and CE are related, and that members of one clan are derived from a circular permutation of the structure of the other.Clan CL includes proteins with a sortase B-like fold. Peptidases in the clan hydrolyse and transfer bacterial cell wall peptides. The fold shows a closed β-barrel decorated with helices with the active site at one end of the barrel []. The active site consists of a His/Cys catalytic dyad.Cysteine peptidases with a chymotrypsin-like fold are included in clan PA, which also includes serine peptidases. Cysteine peptidases that are N-terminal nucleophile hydrolases are included in clan PB. Cysteine peptidases with a tertiary structure similar to that of the serine-type aspartyl dipeptidase are included in clan PC. Cysteine peptidases with an intein-like fold are included in clan PD, which also includes asparagine lyases.
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Publication
17187680 | J:124150
 
First Author: Jabba SV
Year: 2006
Journal: BMC Med
Title: Macrophage invasion contributes to degeneration of stria vascularis in Pendred syndrome mouse model.
Volume: 4
Pages: 37
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Publication
28934227 | J:249830
First Author: Kiang JG
Year: 2017
Journal: PLoS One
Title: Hemorrhage enhances cytokine, complement component 3, and caspase-3, and regulates microRNAs associated with intestinal damage after whole-body gamma-irradiation in combined injury.
Volume: 12
Issue: 9
Pages: e0184393
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Publication
15672593 | J:94068
First Author: Stover CM
Year: 2004
Journal: Mamm Genome
Title: Organization of the MASP2 locus and its expression profile in mouse and rat.
Volume: 15
Issue: 11
Pages: 887-900
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Publication
19297024 | J:148359
First Author: An G
Year: 2009
Journal: Mol Immunol
Title: CD59 but not DAF deficiency accelerates atherosclerosis in female ApoE knockout mice.
Volume: 46
Issue: 8-9
Pages: 1702-9
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Publication
20675597 | J:163254
First Author: Renner B
Year: 2010
Journal: J Immunol
Title: The complement inhibitors Crry and factor H are critical for preventing autologous complement activation on renal tubular epithelial cells.
Volume: 185
Issue: 5
Pages: 3086-94
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Publication
20038603 | J:156544
First Author: Takahashi M
Year: 2010
Journal: J Exp Med
Title: Essential role of mannose-binding lectin-associated serine protease-1 in activation of the complement factor D.
Volume: 207
Issue: 1
Pages: 29-37
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Publication
20299685 | J:180868
First Author: Sakuma M
Year: 2010
Journal: Arterioscler Thromb Vasc Biol
Title: The intrinsic complement regulator decay-accelerating factor modulates the biological response to vascular injury.
Volume: 30
Issue: 6
Pages: 1196-202
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Publication
38372645 | J:348079
First Author: Kang L
Year: 2024
Journal: J Immunol
Title: Critical Role of CD55 in Controlling Wound Healing.
Volume: 212
Issue: 7
Pages: 1142-1149
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Publication
10559481 | J:58620
First Author: Folberg A
Year: 1999
Journal: Mech Dev
Title: Hoxd4 and Rarg interact synergistically in the specification of the cervical vertebrae.
Volume: 89
Issue: 1-2
Pages: 65-74
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Publication
27476854 | J:269738
   
First Author: Guerreiro I
Year: 2016
Journal: Elife
Title: Reorganisation of Hoxd regulatory landscapes during the evolution of a snake-like body plan.
Volume: 5
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Publication
33229569 | J:299264
First Author: Rodríguez-Carballo E
Year: 2020
Journal: Proc Natl Acad Sci U S A
Title: Chromatin topology and the timing of enhancer function at the HoxD locus.
Volume: 117
Issue: 49
Pages: 31231-31241
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Protein Coding Gene
MGI:1352467 | Esr1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:96238 | Hsf1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:97276 | Myog
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1261827 | Dnmt3a
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:2652894 | Mapk15
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1276535 | Ncoa3
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:108069 | Ccna2
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:101947 | Hnrnpd
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:98475 | Tacr1
Type: protein_coding_gene
Organism: mouse, laboratory
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