Type |
Details |
Score |
Publication |
First Author: |
Chen H |
Year: |
2017 |
Journal: |
Oncogene |
Title: |
Hepatic cyclooxygenase-2 overexpression induced spontaneous hepatocellular carcinoma formation in mice. |
Volume: |
36 |
Issue: |
31 |
Pages: |
4415-4426 |
|
•
•
•
•
•
|
Publication |
First Author: |
Su HY |
Year: |
2016 |
Journal: |
PLoS One |
Title: |
The Unfolded Protein Response Plays a Predominant Homeostatic Role in Response to Mitochondrial Stress in Pancreatic Stellate Cells. |
Volume: |
11 |
Issue: |
2 |
Pages: |
e0148999 |
|
•
•
•
•
•
|
Publication |
First Author: |
Genzer Y |
Year: |
2016 |
Journal: |
Mol Cell Endocrinol |
Title: |
Effect of dietary fat and the circadian clock on the expression of brain-derived neurotrophic factor (BDNF). |
Volume: |
430 |
|
Pages: |
49-55 |
|
•
•
•
•
•
|
Publication |
First Author: |
Fujimura K |
Year: |
2018 |
Journal: |
Cancer Res |
Title: |
KRAS Oncoprotein Expression Is Regulated by a Self-Governing eIF5A-PEAK1 Feed-Forward Regulatory Loop. |
Volume: |
78 |
Issue: |
6 |
Pages: |
1444-1456 |
|
•
•
•
•
•
|
Publication |
First Author: |
Qiao L |
Year: |
2023 |
Journal: |
Cell Signal |
Title: |
NAA20 recruits Rin2 and promotes triple-negative breast cancer progression by regulating Rab5A-mediated activation of EGFR signaling. |
Volume: |
112 |
|
Pages: |
110922 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhang DM |
Year: |
2019 |
Journal: |
Free Radic Biol Med |
Title: |
TIGAR alleviates ischemia/reperfusion-induced autophagy and ischemic brain injury. |
Volume: |
137 |
|
Pages: |
13-23 |
|
•
•
•
•
•
|
Publication |
First Author: |
Liu T |
Year: |
2019 |
Journal: |
Front Immunol |
Title: |
IL-17A-Mediated Excessive Autophagy Aggravated Neuronal Ischemic Injuries via Src-PP2B-mTOR Pathway. |
Volume: |
10 |
|
Pages: |
2952 |
|
•
•
•
•
•
|
Publication |
First Author: |
Iffland PH 2nd |
Year: |
2020 |
Journal: |
Exp Neurol |
Title: |
Dynamic analysis of 4E-BP1 phosphorylation in neurons with Tsc2 or Depdc5 knockout. |
Volume: |
334 |
|
Pages: |
113432 |
|
•
•
•
•
•
|
Publication |
First Author: |
Korponay TC |
Year: |
2020 |
Journal: |
Am J Respir Cell Mol Biol |
Title: |
High CO2 Downregulates Skeletal Muscle Protein Anabolism via AMP-activated Protein Kinase α2-mediated Depressed Ribosomal Biogenesis. |
Volume: |
62 |
Issue: |
1 |
Pages: |
74-86 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lv XF |
Year: |
2020 |
Journal: |
Theranostics |
Title: |
TMEM16A ameliorates vascular remodeling by suppressing autophagy via inhibiting Bcl-2-p62 complex formation. |
Volume: |
10 |
Issue: |
9 |
Pages: |
3980-3993 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ni S |
Year: |
2021 |
Journal: |
Front Cell Dev Biol |
Title: |
Coordinated Formation of IMPDH2 Cytoophidium in Mouse Oocytes and Granulosa Cells. |
Volume: |
9 |
|
Pages: |
690536 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wu L |
Year: |
2018 |
Journal: |
Free Radic Biol Med |
Title: |
C1QTNF1 attenuates angiotensin II-induced cardiac hypertrophy via activation of the AMPKa pathway. |
Volume: |
121 |
|
Pages: |
215-230 |
|
•
•
•
•
•
|
Publication |
First Author: |
Albanese F |
Year: |
2021 |
Journal: |
Neurobiol Dis |
Title: |
Constitutive silencing of LRRK2 kinase activity leads to early glucocerebrosidase deregulation and late impairment of autophagy in vivo. |
Volume: |
159 |
|
Pages: |
105487 |
|
•
•
•
•
•
|
Publication |
First Author: |
Rifki OF |
Year: |
2013 |
Journal: |
J Mol Cell Cardiol |
Title: |
RalGDS-dependent cardiomyocyte autophagy is required for load-induced ventricular hypertrophy. |
Volume: |
59 |
|
Pages: |
128-38 |
|
•
•
•
•
•
|
Publication |
First Author: |
Baraldo M |
Year: |
2020 |
Journal: |
J Cachexia Sarcopenia Muscle |
Title: |
Skeletal muscle mTORC1 regulates neuromuscular junction stability. |
Volume: |
11 |
Issue: |
1 |
Pages: |
208-225 |
|
•
•
•
•
•
|
Publication |
First Author: |
Xu J |
Year: |
2023 |
Journal: |
Cancer Res |
Title: |
MEN1 Degradation Induced by Neddylation and the CUL4B-DCAF7 Axis Promotes Pancreatic Neuroendocrine Tumor Progression. |
Volume: |
83 |
Issue: |
13 |
Pages: |
2226-2247 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhang X |
Year: |
2018 |
Journal: |
Cell Rep |
Title: |
Adipose mTORC1 Suppresses Prostaglandin Signaling and Beige Adipogenesis via the CRTC2-COX-2 Pathway. |
Volume: |
24 |
Issue: |
12 |
Pages: |
3180-3193 |
|
•
•
•
•
•
|
Publication |
First Author: |
Blagih J |
Year: |
2015 |
Journal: |
Immunity |
Title: |
The energy sensor AMPK regulates T cell metabolic adaptation and effector responses in vivo. |
Volume: |
42 |
Issue: |
1 |
Pages: |
41-54 |
|
•
•
•
•
•
|
Publication |
First Author: |
Luis LB |
Year: |
2022 |
Journal: |
Cells |
Title: |
Salmonella Promotes Its Own Survival in B Cells by Inhibiting Autophagy. |
Volume: |
11 |
Issue: |
13 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Tassone B |
Year: |
2017 |
Journal: |
Cell Death Differ |
Title: |
Rictor/mTORC2 deficiency enhances keratinocyte stress tolerance via mitohormesis. |
Volume: |
24 |
Issue: |
4 |
Pages: |
731-746 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hua C |
Year: |
2014 |
Journal: |
Exp Hematol |
Title: |
Rictor/mammalian target of rapamycin 2 regulates the development of Notch1 induced murine T-cell acute lymphoblastic leukemia via forkhead box O3. |
Volume: |
42 |
Issue: |
12 |
Pages: |
1031-40.e1-4 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhang Y |
Year: |
2017 |
Journal: |
J Biol Chem |
Title: |
Neuronal mTORC1 Is Required for Maintaining the Nonreactive State of Astrocytes. |
Volume: |
292 |
Issue: |
1 |
Pages: |
100-111 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhang L |
Year: |
2016 |
Journal: |
Cell Rep |
Title: |
Mammalian Target of Rapamycin Complex 2 Controls CD8 T Cell Memory Differentiation in a Foxo1-Dependent Manner. |
Volume: |
14 |
Issue: |
5 |
Pages: |
1206-1217 |
|
•
•
•
•
•
|
Publication |
First Author: |
Sklarz T |
Year: |
2017 |
Journal: |
Eur J Immunol |
Title: |
mTORC2 regulates multiple aspects of NKT-cell development and function. |
Volume: |
47 |
Issue: |
3 |
Pages: |
516-526 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wang F |
Year: |
2021 |
Journal: |
J Clin Invest |
Title: |
ZFP91 disturbs metabolic fitness and antitumor activity of tumor-infiltrating T cells. |
Volume: |
131 |
Issue: |
19 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Haissaguerre M |
Year: |
2018 |
Journal: |
Mol Metab |
Title: |
mTORC1-dependent increase in oxidative metabolism in POMC neurons regulates food intake and action of leptin. |
Volume: |
12 |
|
Pages: |
98-106 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wang Y |
Year: |
2018 |
Journal: |
J Bone Miner Res |
Title: |
Inactivation of mTORC1 Signaling in Osterix-Expressing Cells Impairs B-cell Differentiation. |
Volume: |
33 |
Issue: |
4 |
Pages: |
732-742 |
|
•
•
•
•
•
|
Publication |
First Author: |
Asrani K |
Year: |
2017 |
Journal: |
J Clin Invest |
Title: |
mTORC1 loss impairs epidermal adhesion via TGF-β/Rho kinase activation. |
Volume: |
127 |
Issue: |
11 |
Pages: |
4001-4017 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bartolomeo R |
Year: |
2017 |
Journal: |
J Clin Invest |
Title: |
mTORC1 hyperactivation arrests bone growth in lysosomal storage disorders by suppressing autophagy. |
Volume: |
127 |
Issue: |
10 |
Pages: |
3717-3729 |
|
•
•
•
•
•
|
Publication |
First Author: |
Norrmén C |
Year: |
2018 |
Journal: |
J Neurosci |
Title: |
mTORC1 Is Transiently Reactivated in Injured Nerves to Promote c-Jun Elevation and Schwann Cell Dedifferentiation. |
Volume: |
38 |
Issue: |
20 |
Pages: |
4811-4828 |
|
•
•
•
•
•
|
Publication |
First Author: |
Luo Y |
Year: |
2017 |
Journal: |
Cell Death Dis |
Title: |
Tsc1 expression by dendritic cells is required to preserve T-cell homeostasis and response. |
Volume: |
8 |
Issue: |
1 |
Pages: |
e2553 |
|
•
•
•
•
•
|
Publication |
First Author: |
Xie M |
Year: |
2024 |
Journal: |
Nat Commun |
Title: |
The level of protein in the maternal murine diet modulates the facial appearance of the offspring via mTORC1 signaling. |
Volume: |
15 |
Issue: |
1 |
Pages: |
2367 |
|
•
•
•
•
•
|
Publication |
First Author: |
Cheng SY |
Year: |
2020 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Altered photoreceptor metabolism in mouse causes late stage age-related macular degeneration-like pathologies. |
Volume: |
117 |
Issue: |
23 |
Pages: |
13094-13104 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lu J |
Year: |
2018 |
Journal: |
J Bone Miner Res |
Title: |
Positive-Feedback Regulation of Subchondral H-Type Vessel Formation by Chondrocyte Promotes Osteoarthritis Development in Mice. |
Volume: |
33 |
Issue: |
5 |
Pages: |
909-920 |
|
•
•
•
•
•
|
Publication |
First Author: |
Chen A |
Year: |
2022 |
Journal: |
Bone Res |
Title: |
mTORC1 induces plasma membrane depolarization and promotes preosteoblast senescence by regulating the sodium channel Scn1a. |
Volume: |
10 |
Issue: |
1 |
Pages: |
25 |
|
•
•
•
•
•
|
Publication |
First Author: |
Xiong Z |
Year: |
2018 |
Journal: |
Biol Reprod |
Title: |
Raptor directs Sertoli cell cytoskeletal organization and polarity in the mouse testis. |
Volume: |
99 |
Issue: |
6 |
Pages: |
1289-1302 |
|
•
•
•
•
•
|
Publication |
First Author: |
Israeli T |
Year: |
2022 |
Journal: |
Diabetes |
Title: |
Nutrient Sensor mTORC1 Regulates Insulin Secretion by Modulating β-Cell Autophagy. |
Volume: |
71 |
Issue: |
3 |
Pages: |
453-469 |
|
•
•
•
•
•
|
Publication |
First Author: |
Parker SJ |
Year: |
2018 |
Journal: |
Am J Physiol Heart Circ Physiol |
Title: |
Proteomics reveals Rictor as a noncanonical TGF-β signaling target during aneurysm progression in Marfan mice. |
Volume: |
315 |
Issue: |
5 |
Pages: |
H1112-H1126 |
|
•
•
•
•
•
|
Publication |
First Author: |
Aimi F |
Year: |
2015 |
Journal: |
Sci Rep |
Title: |
Endothelial Rictor is crucial for midgestational development and sustained and extensive FGF2-induced neovascularization in the adult. |
Volume: |
5 |
|
Pages: |
17705 |
|
•
•
•
•
•
|
Publication |
First Author: |
Iskarpatyoti JA |
Year: |
2022 |
Journal: |
Cell Rep |
Title: |
Mast cell regranulation requires a metabolic switch involving mTORC1 and a glucose-6-phosphate transporter. |
Volume: |
40 |
Issue: |
13 |
Pages: |
111346 |
|
•
•
•
•
•
|
Publication |
First Author: |
Michon FX |
Year: |
2023 |
Journal: |
Mol Brain |
Title: |
mTORC1-mediated acquisition of reward-related representations by hippocampal somatostatin interneurons. |
Volume: |
16 |
Issue: |
1 |
Pages: |
55 |
|
•
•
•
•
•
|
Publication |
First Author: |
Honoré E |
Year: |
2022 |
Journal: |
Mol Brain |
Title: |
Object location learning in mice requires hippocampal somatostatin interneuron activity and is facilitated by mTORC1-mediated long-term potentiation of their excitatory synapses. |
Volume: |
15 |
Issue: |
1 |
Pages: |
101 |
|
•
•
•
•
•
|
Publication |
First Author: |
Crewe C |
Year: |
2019 |
Journal: |
JCI Insight |
Title: |
SREBP-regulated adipocyte lipogenesis is dependent on substrate availability and redox modulation of mTORC1. |
Volume: |
5 |
Issue: |
15 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Zhang Y |
Year: |
2021 |
Journal: |
FASEB J |
Title: |
Rictor/mTORC2 is involved in endometrial receptivity by regulating epithelial remodeling. |
Volume: |
35 |
Issue: |
7 |
Pages: |
e21731 |
|
•
•
•
•
•
|
Publication |
First Author: |
Shah OJ |
Year: |
2006 |
Journal: |
Mol Cell Biol |
Title: |
Turnover of the active fraction of IRS1 involves raptor-mTOR- and S6K1-dependent serine phosphorylation in cell culture models of tuberous sclerosis. |
Volume: |
26 |
Issue: |
17 |
Pages: |
6425-34 |
|
•
•
•
•
•
|
Publication |
First Author: |
Le TDV |
Year: |
2023 |
Journal: |
Elife |
Title: |
Glucagon-like peptide-1 receptor activation stimulates PKA-mediated phosphorylation of Raptor and this contributes to the weight loss effect of liraglutide. |
Volume: |
12 |
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Kouloulia S |
Year: |
2019 |
Journal: |
Cell Rep |
Title: |
Raptor-Mediated Proteasomal Degradation of Deamidated 4E-BP2 Regulates Postnatal Neuronal Translation and NF-κB Activity. |
Volume: |
29 |
Issue: |
11 |
Pages: |
3620-3635.e7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Guridi M |
Year: |
2016 |
Journal: |
Skelet Muscle |
Title: |
Alterations to mTORC1 signaling in the skeletal muscle differentially affect whole-body metabolism. |
Volume: |
6 |
|
Pages: |
13 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
324
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
321
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
297
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
260
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
324
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
271
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
238
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
321
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
397
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
373
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
396
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Iwasaki K |
Year: |
2023 |
Journal: |
Front Endocrinol (Lausanne) |
Title: |
Decreased IGF1R attenuates senescence and improves function in pancreatic β-cells. |
Volume: |
14 |
|
Pages: |
1203534 |
|
•
•
•
•
•
|
Publication |
First Author: |
Nordströma U |
Year: |
2015 |
Journal: |
Neurobiol Dis |
Title: |
Progressive nigrostriatal terminal dysfunction and degeneration in the engrailed1 heterozygous mouse model of Parkinson's disease. |
Volume: |
73 |
|
Pages: |
70-82 |
|
•
•
•
•
•
|
Publication |
First Author: |
Tong L |
Year: |
2023 |
Journal: |
J Cachexia Sarcopenia Muscle |
Title: |
AAV1.NT-3 gene therapy in the SOD1KO mouse model of accelerated sarcopenia. |
Volume: |
14 |
Issue: |
5 |
Pages: |
2204-2215 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhang S |
Year: |
2024 |
Journal: |
Circulation |
Title: |
Targeting NPM1 Epigenetically Promotes Postinfarction Cardiac Repair by Reprogramming Reparative Macrophage Metabolism. |
Volume: |
149 |
Issue: |
25 |
Pages: |
1982-2001 |
|
•
•
•
•
•
|
Publication |
First Author: |
Barrows CM |
Year: |
2017 |
Journal: |
J Neurosci |
Title: |
PTEN Loss Increases the Connectivity of Fast Synaptic Motifs and Functional Connectivity in a Developing Hippocampal Network. |
Volume: |
37 |
Issue: |
36 |
Pages: |
8595-8611 |
|
•
•
•
•
•
|
Publication |
First Author: |
Getz SA |
Year: |
2022 |
Journal: |
J Neurosci |
Title: |
PTEN Regulates Dendritic Arborization by Decreasing Microtubule Polymerization Rate. |
Volume: |
42 |
Issue: |
10 |
Pages: |
1945-1957 |
|
•
•
•
•
•
|
Publication |
First Author: |
Getz SA |
Year: |
2016 |
Journal: |
Neurobiol Dis |
Title: |
Rapamycin prevents, but does not reverse, aberrant migration in Pten knockout neurons. |
Volume: |
93 |
|
Pages: |
12-20 |
|
•
•
•
•
•
|
Publication |
First Author: |
Domènech-Estévez E |
Year: |
2016 |
Journal: |
J Neurosci |
Title: |
Akt Regulates Axon Wrapping and Myelin Sheath Thickness in the PNS. |
Volume: |
36 |
Issue: |
16 |
Pages: |
4506-21 |
|
•
•
•
•
•
|
Publication |
First Author: |
Le Bacquer O |
Year: |
2019 |
Journal: |
J Cachexia Sarcopenia Muscle |
Title: |
4E-BP1 and 4E-BP2 double knockout mice are protected from aging-associated sarcopenia. |
Volume: |
10 |
Issue: |
3 |
Pages: |
696-709 |
|
•
•
•
•
•
|
Publication |
First Author: |
Weisser I |
Year: |
2024 |
Journal: |
J Am Soc Nephrol |
Title: |
Ablation of Long Noncoding RNA Hoxb3os Exacerbates Cystogenesis in Mouse Polycystic Kidney Disease. |
Volume: |
35 |
Issue: |
1 |
Pages: |
41-55 |
|
•
•
•
•
•
|
Publication |
First Author: |
Brazill JM |
Year: |
2023 |
Journal: |
Mol Metab |
Title: |
Knockout of TSC2 in Nav1.8+ neurons predisposes to the onset of normal weight obesity. |
Volume: |
68 |
|
Pages: |
101664 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wang S |
Year: |
2019 |
Journal: |
Autophagy |
Title: |
Impaired TFEB-mediated lysosomal biogenesis promotes the development of pancreatitis in mice and is associated with human pancreatitis. |
Volume: |
15 |
Issue: |
11 |
Pages: |
1954-1969 |
|
•
•
•
•
•
|
Publication |
First Author: |
Megat S |
Year: |
2019 |
Journal: |
J Neurosci |
Title: |
Differences between dorsal root and trigeminal ganglion nociceptors in mice revealed by translational profiling. |
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|
|
•
•
•
•
•
|
Publication |
First Author: |
Salazar G |
Year: |
2020 |
Journal: |
Autophagy |
Title: |
SQSTM1/p62 and PPARGC1A/PGC-1alpha at the interface of autophagy and vascular senescence. |
Volume: |
16 |
Issue: |
6 |
Pages: |
1092-1110 |
|
•
•
•
•
•
|
Publication |
First Author: |
Saré RM |
Year: |
2022 |
Journal: |
eNeuro |
Title: |
Confirmation of Decreased Rates of Cerebral Protein Synthesis In Vivo in a Mouse Model of Tuberous Sclerosis Complex. |
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|
•
•
•
•
•
|
Publication |
First Author: |
Pan B |
Year: |
2019 |
Journal: |
Front Physiol |
Title: |
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