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Search results 401 to 500 out of 1263 for Abr

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Type Details Score
Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
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Publication
- | J:72247
       
First Author: DDB, FB, MGI, GOA, ZFIN curators
Year: 2001
Title: Gene Ontology annotation through association of InterPro records with GO terms
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:148605
     
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Allele
Abr<tm1Jhg> | MGI:2388713
Name: active BCR-related gene; targeted mutation 1, John H Groffen
Allele Type: Targeted
Attribute String: Null/knockout
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Publication
10320101 | J:54812
First Author: Zheng QY
Year: 1999
Journal: Hear Res
Title: Assessment of hearing in 80 inbred strains of mice by ABR threshold analyses.
Volume: 130
Issue: 1-2
Pages: 94-107
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Publication
34487237 | J:329527
First Author: Lavinsky J
Year: 2021
Journal: Mamm Genome
Title: Large-scale phenotyping of ABR P1-N1 amplitudes before and after exposure to noise in 69 strains of mice.
Volume: 32
Issue: 6
Pages: 427-434
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Publication
30894204 | J:283167
First Author: Lundt A
Year: 2019
Journal: BMC Res Notes
Title: Gender specific click and tone burst evoked ABR datasets from mice lacking the Cav3.2 T-type voltage-gated calcium channel.
Volume: 12
Issue: 1
Pages: 157
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Interaction Experiment
Cho YJ (2007)
Description: Abr and Bcr, two homologous Rac GTPase-activating proteins, control multiple cellular functions of murine macrophages.
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Allele
Pdzd7<tm1a(EUCOMM)Wtsi> | MGI:4433578
Name: PDZ domain containing 7; targeted mutation 1a, Wellcome Trust Sanger Institute
Allele Type: Targeted
Attribute String: Conditional ready, Null/knockout, Reporter
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Publication
26401052 | J:226845
First Author: Zou J
Year: 2015
Journal: Hum Mol Genet
Title: Individual USH2 proteins make distinct contributions to the ankle link complex during development of the mouse cochlear stereociliary bundle.
Volume: 24
Issue: 24
Pages: 6944-57
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Publication
28031293 | J:241430
First Author: Zou J
Year: 2017
Journal: Hum Mol Genet
Title: The roles of USH1 proteins and PDZ domain-containing USH proteins in USH2 complex integrity in cochlear hair cells.
Volume: 26
Issue: 3
Pages: 624-636
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Strain
MGI:5581864 | C57BL/6N-Pdzd7<tm1a(EUCOMM)Wtsi>
Attribute String: coisogenic, mutant strain, targeted mutation
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Genotype
Genotype
Symbol: Pdzd7/Pdzd7
Background: involves: C57BL/6J * C57BL/6N
Zygosity: hm
Has Mutant Allele: true
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Heritable Phenotypic Marker
MGI:3811768 | Rgsc114
Type: heritable_phenotypic_marker
Organism: mouse, laboratory
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Publication
24334608 | J:209073
First Author: Zou J
Year: 2014
Journal: Hum Mol Genet
Title: Deletion of PDZD7 disrupts the Usher syndrome type 2 protein complex in cochlear hair cells and causes hearing loss in mice.
Volume: 23
Issue: 9
Pages: 2374-90
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Allele
Nox3<het-2J> | MGI:1857794
 
Name: NADPH oxidase 3; head tilt 2 Jackson
Allele Type: Spontaneous
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Heritable Phenotypic Marker
MGI:3045702 | Cal5
Type: heritable_phenotypic_marker
Organism: mouse, laboratory
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Publication
- | J:91654
     
First Author: Samples RM
Year: 2004
Journal: MGI Direct Data Submission
Title: Caracul-like 5, a dominant mutation resembling Krt2-6gCa (caracul) and mapping to the same chromosomal location. Mouse Mutant Resources Web Site, The Jackson Laboratory, Bar Harbor, Maine
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Publication
15014044 | J:89010
First Author: Paffenholz R
Year: 2004
Journal: Genes Dev
Title: Vestibular defects in head-tilt mice result from mutations in Nox3, encoding an NADPH oxidase.
Volume: 18
Issue: 5
Pages: 486-91
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Publication
- | J:56803
     
First Author: Cook S
Year: 1999
Journal: MGI Direct Data Submission
Title: The Jackson Laboratory Mouse Mutant Resource 1999 Mutation Reports
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Strain
MGI:2165111 | B6 x B10.D1-H2<q>/SgJ-Nox3<het-2J>/J
Attribute String: congenic, mutant stock, coisogenic, major histocompatibility congenic, spontaneous mutation
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Genotype
Genotype
Symbol: Nox3/Nox3
Background: B10.Q-H2/SgJ
Zygosity: hm
Has Mutant Allele: true
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Protein Domain
IPR037865 | ABR_PH
Type: Domain
Description: The active breakpoint cluster region-related protein (ABR) protein contains multiple domains including a RhoGEF domain, a PH domain, a C1 domain, a C2 domain, and a C-terminal RhoGAP domain. It is related to a slightly larger protein, BCR, which is structurally similar, but has an additional N-terminal kinase domain. ABR has GAP activity for both Rac and Cdc42. It promotes the exchange of RAC or CDC42-bound GDP by GTP, thereby activating them []. This entry represents the PH domain of ABR.
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Publication
17973922 | J:149048
First Author: Zhang W
Year: 2008
Journal: Genes Brain Behav
Title: Netrin-G2 and netrin-G2 ligand are both required for normal auditory responsiveness.
Volume: 7
Issue: 4
Pages: 385-92
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Publication
3207006 | J:90423
First Author: Wenngren BI
Year: 1988
Journal: Acta Otolaryngol
Title: Age-related auditory brainstem response (ABR) threshold changes in the dancer mouse mutant.
Volume: 106
Issue: 5-6
Pages: 386-92
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Protein
H3BL84
Organism: Mus musculus/domesticus
Length: 91  
Fragment?: true
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Publication
19840940 | -
First Author: Yi SJ
Year: 2009
Journal: J Biol Chem
Title: Transglutaminase 2 regulates the GTPase-activating activity of Bcr.
Volume: 284
Issue: 51
Pages: 35645-51
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Publication
21310073 | -
 
First Author: Yi SJ
Year: 2011
Journal: BMC Biochem
Title: Bcr is a substrate for Transglutaminase 2 cross-linking activity.
Volume: 12
Pages: 8
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Publication
21295482 | -
First Author: Vaughan EM
Year: 2011
Journal: Curr Biol
Title: Control of local Rho GTPase crosstalk by Abr.
Volume: 21
Issue: 4
Pages: 270-7
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Publication
9376659 | -
First Author: Groffen J
Year: 1997
Journal: Baillieres Clin Haematol
Title: The chimeric BCR-ABL gene.
Volume: 10
Issue: 2
Pages: 187-201
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Publication
8246975 | -
First Author: McWhirter JR
Year: 1993
Journal: Mol Cell Biol
Title: A coiled-coil oligomerization domain of Bcr is essential for the transforming function of Bcr-Abl oncoproteins.
Volume: 13
Issue: 12
Pages: 7587-95
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Protein Domain
IPR037769 | Abr/Bcr
Type: Family
Description: Abr (active breakpoint cluster region-related protein) and Bcr (breakpoint cluster region protein) are homologous proteins containing a C-terminal domain with GTPase-activating protein (GAP) activity specific for Rac. They control multiple cellular functions of murine macrophages []. They contain several domains, including tandem DH-PH, C2 and GAP domains. Bcr has an extra N-terminal oligomerization domain []. Bcr has been shown to fused to Abl tyrosine kinase in leukemia. The fusion of Bcr to Abl deregulates the tyrosine kinase activity of Abl []. The N-terminal oligomerization domain is thought to be the most critical component that allows the formation of homo-tetramer Bcr/Abl complexes and deregulates the Abl tyrosine kinase [, ]. The GTPase-activating activity of Bcr has been shown to be regulated by transglutaminase 2 (TG2), a multifunctional protein that has been implicated in numerous pathologies including that of neurodegeneration and celiac disease [, ].Abr is a critical regulator of Rho and Cdc42 during the single cell wound healing [].
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Publication
24560810 | J:213346
 
First Author: Suzuki J
Year: 2014
Journal: Neurosci Res
Title: Preservation of cochlear function in Fabp3 (H-Fabp) knockout mice.
Volume: 81-82
Pages: 64-8
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Publication
38980136 | J:355477
 
First Author: Burke K
Year: 2024
Journal: JASA Express Lett
Title: Auditory brainstem response audiometry in tauopathy mouse model of human Alzheimer's disease.
Volume: 4
Issue: 7
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Publication
1444930 | J:2853
First Author: Henry KR
Year: 1992
Journal: Audiology
Title: Auditory brainstem function of the F1 offspring of the cross of CBA/CaJ and AU/SsJ inbred mice.
Volume: 31
Issue: 4
Pages: 190-5
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Publication
8340277 | J:14069
First Author: Kirsch JP
Year: 1993
Journal: Hear Res
Title: Mice heterozygous for the deafness gene have normal auditory thresholds.
Volume: 67
Issue: 1-2
Pages: 51-4
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Publication
9804293 | J:103717
First Author: Barros AC
Year: 1998
Journal: Neuroreport
Title: Absence of thyroid hormone receptor beta-retinoid X receptor interactions in auditory function and in the pituitary-thyroid axis.
Volume: 9
Issue: 13
Pages: 2933-7
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Publication
2316343 | J:90425
First Author: Wenngren BI
Year: 1990
Journal: Acta Otolaryngol
Title: Aberrant frequency tuning and early stereociliary derangement in genetic inner ear disease.
Volume: 109
Issue: 3-4
Pages: 202-12
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Publication
35605008 | J:328525
First Author: Maruyama J
Year: 2022
Journal: PLoS Pathog
Title: CD4 T-cell depletion prevents Lassa fever associated hearing loss in the mouse model.
Volume: 18
Issue: 5
Pages: e1010557
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Publication
20057387 | J:250208
First Author: Hardisty-Hughes RE
Year: 2010
Journal: Nat Protoc
Title: A hearing and vestibular phenotyping pipeline to identify mouse mutants with hearing impairment.
Volume: 5
Issue: 1
Pages: 177-90
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Publication
24607930 | J:212007
 
First Author: Nakajima M
Year: 2014
Journal: Neurosci Lett
Title: Dilation of the inferior colliculus and hypersensitivity to sound in Wnt1-cre and Wnt1-GAL4 double-transgenic mice.
Volume: 566
Pages: 236-40
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Publication
15862894 | J:99715
First Author: Shimizu Y
Year: 2005
Journal: Neurosci Lett
Title: Kanamycin ototoxicity in glutamate transporter knockout mice.
Volume: 380
Issue: 3
Pages: 243-6
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Publication
28626386 | J:276647
 
First Author: Lauer AM
Year: 2017
Journal: Front Neurosci
Title: Minimal Effects of Age and Exposure to a Noisy Environment on Hearing in Alpha9 Nicotinic Receptor Knockout Mice.
Volume: 11
Pages: 304
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Publication
24457350 | J:334133
First Author: Yates N
Year: 2014
Journal: Audiol Neurootol
Title: Auditory brainstem responses of ephrin-A2, ephrin-A5(-/-) and ephrin-A2A5(-/-) mice.
Volume: 19
Issue: 2
Pages: 115-26
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Publication
9447922 | J:44966
First Author: Johnson KR
Year: 1997
Journal: Hear Res
Title: A major gene affecting age-related hearing loss in C57BL/6J mice.
Volume: 114
Issue: 1-2
Pages: 83-92
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Publication
19733551 | J:155625
First Author: Kashio A
Year: 2009
Journal: Biochem Biophys Res Commun
Title: Effect of vitamin C depletion on age-related hearing loss in SMP30/GNL knockout mice.
Volume: 390
Issue: 3
Pages: 394-8
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Publication
22485190 | J:224197
First Author: Zhu GJ
Year: 2012
Journal: PLoS One
Title: Myosin light-chain kinase is necessary for membrane homeostasis in cochlear inner hair cells.
Volume: 7
Issue: 4
Pages: e34894
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Publication
- | J:276827
     
First Author: Johnson KR
Year: 2019
Journal: Direct Data Submission from Genetic Resource Science
Title: The spontaneous mutation jitterbug 2 Jackson
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Publication
36206820 | J:331678
 
First Author: Pang R
Year: 2023
Journal: Behav Brain Res
Title: Transient hearing abnormalities precede social deficits in a mouse model of autism.
Volume: 437
Pages: 114149
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Publication
- | J:278662
     
First Author: Gray SJ
Year: 2019
Journal: MGI Direct Data Submission
Title: The deaf circler 4 Jackson spontaneous mutation
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Publication
4044424 | J:24858
First Author: Henry KR
Year: 1985
Journal: Hear Res
Title: ON and OFF components of the auditory brainstem response have different frequency- and intensity-specific properties.
Volume: 18
Issue: 3
Pages: 245-51
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Publication
7829075 | J:59618
First Author: McDonald JD
Year: 1994
Journal: Genomics
Title: Physical mapping of chromosome 17p13.3 in the region of a putative tumor suppressor gene important in medulloblastoma.
Volume: 23
Issue: 1
Pages: 229-32
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Publication
7607988 | J:25486
First Author: Sone M
Year: 1995
Journal: Hear Res
Title: A substrain of NZB mouse as an animal model of autoimmune inner ear disease.
Volume: 83
Issue: 1-2
Pages: 26-36
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Publication
28739348 | J:252256
 
First Author: Marie A
Year: 2017
Journal: Neurosci Lett
Title: Senescence-accelerated mouse prone 8 (SAMP8) as a model of age-related hearing loss.
Volume: 656
Pages: 138-143
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Protein Coding Gene
MGI:2159341 | Ntng2
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CAROLIEiJ_G0023365 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGI:2182081 | Lrrc4
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CAROLIEiJ_G0028160 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0025538 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_129S1SvImJ_G0030512 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0025515 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0030485 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0025485 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0030412 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0025511 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0030495 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0025272 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0030208 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_2159341 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_2182081 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0025955 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0030949 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0024735 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0029610 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0025250 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0030186 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0025383 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0030330 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0025345 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

© 2002 - 2017 Department of Genetics, University of Cambridge, Downing Street,
Cambridge CB2 3EH, United Kingdom