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Search results 401 to 458 out of 458 for Acp5

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0.026s
Type Details Score
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Allele
Name: acid phosphatase 5, tartrate resistant; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
Allele
Name: transgene insertion, Roland Schule
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
Strain
Attribute String: coisogenic, mutant strain, transgenic
Allele
Name: transgene insertion, Daewon Jeong
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
Allele
Name: transgene insertion 1, Rene St-Arnaud
Allele Type: Transgenic
Attribute String: Recombinase
Strain
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
Genotype
Symbol: Tg(Acp5-Fhl2)#Rosc/?
Background: FVB/N-Tg(Acp5-Fhl2)#Rosc
Zygosity: ot
Has Mutant Allele: true
Genotype
Symbol: Tg(Acp5-Selenow)#Djeo/?
Background: involves: FVB/N
Zygosity: ot
Has Mutant Allele: true
Allele
Name: transgene insertion 3, Rachel A Davey
Allele Type: Transgenic
Attribute String: Recombinase
Allele
Name: transgene insertion 4, Rachel A Davey
Allele Type: Transgenic
Attribute String: Recombinase
Publication
First Author: Alanne MH
Year: 2012
Journal: J Cell Biochem
Title: Phenotypic characterization of transgenic mice harboring Nf1+/- or Nf1-/- osteoclasts in otherwise Nf1+/+ background.
Volume: 113
Issue: 6
Pages: 2136-46
Allele
Name: transgene insertion 1, G David Roodman
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
Allele
Name: transgene insertion 11.40, Mouse Clinical Institute
Allele Type: Transgenic
Attribute String: Recombinase
Publication
First Author: Jiang H
Year: 2015
Journal: FASEB J
Title: Adseverin plays a role in osteoclast differentiation and periodontal disease-mediated bone loss.
Volume: 29
Issue: 6
Pages: 2281-91
Publication  
First Author: Miyagawa K
Year: 2023
Journal: JCI Insight
Title: Osteoclast-derived IGF1 induces RANKL production in osteocytes and contributes to pagetic lesion formation.
Volume: 8
Issue: 14
Publication  
First Author: Su W
Year: 2020
Journal: JCI Insight
Title: Angiogenesis stimulated by elevated PDGF-BB in subchondral bone contributes to osteoarthritis development.
Volume: 5
Issue: 8
Publication
First Author: Rindone AN
Year: 2021
Journal: Nat Commun
Title: Quantitative 3D imaging of the cranial microvascular environment at single-cell resolution.
Volume: 12
Issue: 1
Pages: 6219
Publication
First Author: Reddy SV
Year: 2001
Journal: Endocrinology
Title: Osteoclasts formed by measles virus-infected osteoclast precursors from hCD46 transgenic mice express characteristics of pagetic osteoclasts.
Volume: 142
Issue: 7
Pages: 2898-905
Strain
Attribute String: congenic, mutant strain, transgenic
Genotype
Symbol: Ilk/Ilk Tg(Acp5-cre)1Star/?
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Scin/Scin Tg(Acp5-cre)4Rda/?
Background: either: (involves: 129 * C57BL/6) or (involves: 129 * C57BL/6 * CBA)
Zygosity: cn
Has Mutant Allele: true
Strain
Attribute String: targeted mutation, transgenic, congenic
Genotype
Symbol: Calcr/Calcr Tg(Acp5-cre)4Rda/?
Background: B6.Cg-Calcr Tg(Acp5-cre)4Rda
Zygosity: cn
Has Mutant Allele: true
Publication
First Author: Günther T
Year: 2005
Journal: EMBO J
Title: Fhl2 deficiency results in osteopenia due to decreased activity of osteoblasts.
Volume: 24
Issue: 17
Pages: 3049-56
Allele
Name: transgene insertion 28-4-3, Peter Maye
Allele Type: Transgenic
Attribute String: Reporter
Publication
First Author: Adjei-Sowah E
Year: 2024
Journal: Sci Adv
Title: Development of a nanoparticle-based tendon-targeting drug delivery system to pharmacologically modulate tendon healing.
Volume: 10
Issue: 25
Pages: eadn2332
Publication
First Author: Schwarz T
Year: 2010
Journal: Biochem Biophys Res Commun
Title: C-TAK1 interacts with microphthalmia-associated transcription factor, Mitf, but not the related family member Tfe3.
Volume: 394
Issue: 4
Pages: 890-5
Publication
First Author: Schwarz T
Year: 2010
Journal: J Cell Biochem
Title: The 19S proteasomal lid subunit POH1 enhances the transcriptional activation by Mitf in osteoclasts.
Volume: 109
Issue: 5
Pages: 967-74
Publication
First Author: Sträter N
Year: 2005
Journal: J Mol Biol
Title: Crystal structures of recombinant human purple Acid phosphatase with and without an inhibitory conformation of the repression loop.
Volume: 351
Issue: 1
Pages: 233-46
Publication
First Author: del Pozo JC
Year: 1999
Journal: Plant J
Title: A type 5 acid phosphatase gene from Arabidopsis thaliana is induced by phosphate starvation and by some other types of phosphate mobilising/oxidative stress conditions.
Volume: 19
Issue: 5
Pages: 579-89
Publication
First Author: Zhu H
Year: 2005
Journal: Plant Mol Biol
Title: Expression patterns of purple acid phosphatase genes in Arabidopsis organs and functional analysis of AtPAP23 predominantly transcribed in flower.
Volume: 59
Issue: 4
Pages: 581-94
Protein Domain
Type: Family
Description: This entry includes purple acid phosphatases (EC 3.1.3.2), which are metal dependent, binding two metal ions. Metal binding ligands and residues involved in resistance to tartrate inhibition are conserved [].Purple acid phosphatase 3, 4, 7, 8 and 17 are found in plants, bind zinc and iron, and the genes are predominantly transcribed in flowers []. Purple acid phosphatase 17 (PAP17) is induced in response to phosphate starvation, a condition occurring in phosphate-poor soils, and the plant hormone abscisic acid (ABA) and salt stress. Like mammalian acid phosphatase 5, PAP17 has peroxidation activity [].Acid phosphatase 5 (ACP5; EC 3.1.3.2) removes the mannose 6-phosphate recognition marker from lysosomal proteins. The exact site of dephosphorylation is not clear. Evidence suggests dephosphorylation may take place in a prelysosomal compartment as well as in the lysosome []. ACP5 belongs to the metallophosphatase (MPP) superfamily. MPPs are functionally diverse, but all share a conserved domain with an active site consisting of two metal ions (usually manganese, iron, or zinc) co-ordinated with octahedral geometry by a cage of histidine, aspartate, and asparagine residues [].
Publication
First Author: Xie H
Year: 2014
Journal: Nat Med
Title: PDGF-BB secreted by preosteoclasts induces angiogenesis during coupling with osteogenesis.
Volume: 20
Issue: 11
Pages: 1270-8
Publication
First Author: Kim H
Year: 2021
Journal: Nat Commun
Title: Selenoprotein W ensures physiological bone remodeling by preventing hyperactivity of osteoclasts.
Volume: 12
Issue: 1
Pages: 2258
Publication
First Author: Davey RA
Year: 2008
Journal: J Bone Miner Res
Title: Calcitonin receptor plays a physiological role to protect against hypercalcemia in mice.
Volume: 23
Issue: 8
Pages: 1182-93
Publication
First Author: Ni S
Year: 2019
Journal: Nat Commun
Title: Sensory innervation in porous endplates by Netrin-1 from osteoclasts mediates PGE2-induced spinal hypersensitivity in mice.
Volume: 10
Issue: 1
Pages: 5643
Strain
Attribute String: mutant stock, transgenic
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Acp5-cre)3Rda/?
Background: involves: 129S4/SvJaeSor * C57BL/6
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Acp5-cre)4Rda/?
Background: involves: 129S4/SvJaeSor * C57BL/6
Zygosity: cn
Has Mutant Allele: true
Publication
First Author: Hu R
Year: 2007
Journal: Mol Cell Biol
Title: Eos, MITF, and PU.1 recruit corepressors to osteoclast-specific genes in committed myeloid progenitors.
Volume: 27
Issue: 11
Pages: 4018-27
Publication
First Author: Chawalitpong S
Year: 2018
Journal: Sci Rep
Title: Cyperenoic acid suppresses osteoclast differentiation and delays bone loss in a senile osteoporosis mouse model by inhibiting non-canonical NF-κB pathway.
Volume: 8
Issue: 1
Pages: 5625
Publication
First Author: Ripoll VM
Year: 2008
Journal: Gene
Title: Microphthalmia transcription factor regulates the expression of the novel osteoclast factor GPNMB.
Volume: 413
Issue: 1-2
Pages: 32-41
Publication
First Author: Bronisz A
Year: 2014
Journal: J Biol Chem
Title: The multifunctional protein fused in sarcoma (FUS) is a coactivator of microphthalmia-associated transcription factor (MITF).
Volume: 289
Issue: 1
Pages: 326-34
Publication  
First Author: Li D
Year: 2020
Journal: Int J Mol Sci
Title: METTL3 Modulates Osteoclast Differentiation and Function by Controlling RNA Stability and Nuclear Export.
Volume: 21
Issue: 5
Protein
Organism: Mus musculus/domesticus
Length: 327  
Fragment?: false
Publication
First Author: Dossa T
Year: 2010
Journal: J Cell Biochem
Title: Osteoclast-specific inactivation of the integrin-linked kinase (ILK) inhibits bone resorption.
Volume: 110
Issue: 4
Pages: 960-7
Publication
First Author: Chiu WS
Year: 2004
Journal: Genesis
Title: Transgenic mice that express Cre recombinase in osteoclasts.
Volume: 39
Issue: 3
Pages: 178-85
Publication  
First Author: Maye P
Year: 2009
Journal: BMC Biotechnol
Title: A BAC-bacterial recombination method to generate physically linked multiple gene reporter DNA constructs.
Volume: 9
Pages: 20
Publication
First Author: Fretz JA
Year: 2008
Journal: Mol Endocrinol
Title: Receptor activator of nuclear factor-kappaB ligand-induced nuclear factor of activated T cells (C1) autoregulates its own expression in osteoclasts and mediates the up-regulation of tartrate-resistant acid phosphatase.
Volume: 22
Issue: 3
Pages: 737-50
Publication  
First Author: Le PT
Year: 2021
Journal: Bone
Title: The role of Zfp467 in mediating the pro-osteogenic and anti-adipogenic effects on bone and bone marrow niche.
Volume: 144
Pages: 115832
Publication
First Author: Otero JE
Year: 2010
Journal: J Bone Miner Res
Title: IKKbeta activation is sufficient for RANK-independent osteoclast differentiation and osteolysis.
Volume: 25
Issue: 6
Pages: 1282-94
Publication
First Author: Fu Y
Year: 2015
Journal: Genesis
Title: Derivation of chondrocyte and osteoblast reporter mouse embryonic stem cell lines.
Volume: 53
Issue: 3-4
Pages: 294-8
Publication      
First Author: European Mouse Mutant Archive
Year: 2003
Journal: Unpublished
Title: Information obtained from the European Mouse Mutant Archive (EMMA)