Type |
Details |
Score |
Publication |
First Author: |
DDB, FB, MGI, GOA, ZFIN curators |
Year: |
2001 |
|
Title: |
Gene Ontology annotation through association of InterPro records with GO terms |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Magdaleno S |
Year: |
2006 |
Journal: |
PLoS Biol |
Title: |
BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. |
Volume: |
4 |
Issue: |
4 |
Pages: |
e86 |
|
•
•
•
•
•
|
Publication |
First Author: |
Carninci P |
Year: |
2005 |
Journal: |
Science |
Title: |
The transcriptional landscape of the mammalian genome. |
Volume: |
309 |
Issue: |
5740 |
Pages: |
1559-63 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kawai J |
Year: |
2001 |
Journal: |
Nature |
Title: |
Functional annotation of a full-length mouse cDNA collection. |
Volume: |
409 |
Issue: |
6821 |
Pages: |
685-90 |
|
•
•
•
•
•
|
Publication |
First Author: |
MGD Nomenclature Committee |
Year: |
1995 |
|
Title: |
Nomenclature Committee Use |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
GemPharmatech |
Year: |
2020 |
|
Title: |
GemPharmatech Website. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Cyagen Biosciences Inc. |
Year: |
2022 |
|
Title: |
Cyagen Biosciences Website. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
The Jackson Laboratory Mouse Radiation Hybrid Database |
Year: |
2004 |
Journal: |
Database Release |
Title: |
Mouse T31 Radiation Hybrid Data Load |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Okazaki Y |
Year: |
2002 |
Journal: |
Nature |
Title: |
Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. |
Volume: |
420 |
Issue: |
6915 |
Pages: |
563-73 |
|
•
•
•
•
•
|
Publication |
First Author: |
The Gene Ontology Consortium |
Year: |
2010 |
|
Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Diez-Roux G |
Year: |
2011 |
Journal: |
PLoS Biol |
Title: |
A high-resolution anatomical atlas of the transcriptome in the mouse embryo. |
Volume: |
9 |
Issue: |
1 |
Pages: |
e1000582 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2002 |
|
Title: |
Mouse Genome Informatics Computational Sequence to Gene Associations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2). |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
MGI Genome Annotation Group and UniGene Staff |
Year: |
2015 |
Journal: |
Database Download |
Title: |
MGI-UniGene Interconnection Effort |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas |
Year: |
2010 |
|
Title: |
Annotation inferences using phylogenetic trees |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Allen Institute for Brain Science |
Year: |
2004 |
Journal: |
Allen Institute |
Title: |
Allen Brain Atlas: mouse riboprobes |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Consensus CDS project |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Group |
Year: |
2003 |
Journal: |
Database Procedure |
Title: |
Automatic Encodes (AutoE) Reference |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Bairoch A |
Year: |
1999 |
Journal: |
Database Release |
Title: |
SWISS-PROT Annotated protein sequence database |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics |
Year: |
2010 |
Journal: |
Database Release |
Title: |
Protein Ontology Association Load. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
|
|
|
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
392
 |
Fragment?: |
false |
|
•
•
•
•
•
|
GO Term |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
513
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
414
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
392
 |
Fragment?: |
false |
|
•
•
•
•
•
|
SO Term |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
GO Term |
|
•
•
•
•
•
|
Allele |
Name: |
angiotensinogen; targeted mutation 1, University of North Carolina |
Allele Type: |
Targeted |
Attribute String: |
Null/knockout |
|
•
•
•
•
•
|
Strain |
Attribute String: |
mutant strain, congenic, targeted mutation |
|
•
•
•
•
•
|
Strain |
Attribute String: |
congenic, mutant strain, targeted mutation |
|
•
•
•
•
•
|
Allele |
Name: |
angiotensinogen; targeted mutation 2, University of North Carolina |
Allele Type: |
Targeted |
|
|
•
•
•
•
•
|
Strain |
Attribute String: |
congenic, mutant strain, targeted mutation |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Agt/Agt<+> |
Background: |
involves: 129P2/OlaHsd * C57BL/6J |
Zygosity: |
ht |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Agt/Agt<+> |
Background: |
involves: 129P2/OlaHsd * C57BL/6J |
Zygosity: |
ht |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Agt/Agt |
Background: |
involves: 129P2/OlaHsd * C57BL/6J |
Zygosity: |
hm |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Agt/Agt |
Background: |
involves: 129P2/OlaHsd * C57BL/6J |
Zygosity: |
hm |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
DO Term |
|
•
•
•
•
•
|
Allele |
Name: |
angiotensinogen; endonuclease-mediated mutation 1, Shanghai Model Organisms Center |
Allele Type: |
Endonuclease-mediated |
Attribute String: |
Null/knockout |
|
•
•
•
•
•
|
Allele |
Name: |
angiotensinogen; targeted mutation 1, Shanghai Model Organisms Center |
Allele Type: |
Targeted |
Attribute String: |
Humanized sequence, Inserted expressed sequence |
|
•
•
•
•
•
|
Publication |
First Author: |
Larivière L |
Year: |
2005 |
Journal: |
J Mol Biol |
Title: |
Structural evidence of a passive base-flipping mechanism for AGT, an unusual GT-B glycosyltransferase. |
Volume: |
352 |
Issue: |
1 |
Pages: |
139-50 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bryson AL |
Year: |
2015 |
Journal: |
mBio |
Title: |
Covalent Modification of Bacteriophage T4 DNA Inhibits CRISPR-Cas9. |
Volume: |
6 |
Issue: |
3 |
Pages: |
e00648 |
|
•
•
•
•
•
|
Publication |
First Author: |
Sommer N |
Year: |
2004 |
Journal: |
Biochem Biophys Res Commun |
Title: |
Bacteriophage T4 alpha-glucosyltransferase: a novel interaction with gp45 and aspects of the catalytic mechanism. |
Volume: |
323 |
Issue: |
3 |
Pages: |
809-15 |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
The T4 bacteriophage of E.coli protects its DNA via two glycosyltransferases which glucosylate 5-hydroxymethyl cytosines (5-HMC) using UDP-glucose. These two proteins are the retaining alpha-glucosyltransferase (AGT) and the inverting beta-glucosyltransferase (BGT) [].This entry represents AGT and similar proteins from Uroviricota. AGT catalyses the transfer of glucose from uridine diphosphoglucose to 5-hydroxymethyl cytosine of T4 DNA to yield glucosyl 5-hydroxymethyl cytosine []. This protein adopts the GT-B fold and binds both the sugar donor and acceptor to the C-terminal domain. There is evidence for a role of AGT in the base-flipping mechanism and for its specific recognition of the acceptor base []. AGT interacts with the clamp protein gp45 []. The modification performed by this enzyme protects the phage genome against its own nucleases, the host restriction endonuclease system and against the host CRISPR-Cas9 defence system []. |
|
•
•
•
•
•
|
Allele |
Name: |
stimulator of interferon response cGAMP interactor 1; endonuclease-mediated mutation 1, Russell Vance |
Allele Type: |
Endonuclease-mediated |
|
|
•
•
•
•
•
|
Strain |
Attribute String: |
coisogenic, mutant strain, endonuclease-mediated mutation |
|
•
•
•
•
•
|
Strain |
Attribute String: |
coisogenic, mutant strain, targeted mutation |
|
•
•
•
•
•
|
Strain |
Attribute String: |
coisogenic, endonuclease-mediated mutation, mutant strain |
|
•
•
•
•
•
|
Allele |
Name: |
argonaute RISC catalytic subunit 2; endonuclease-mediated mutation 1, Jonathan G Hanley |
Allele Type: |
Endonuclease-mediated |
Attribute String: |
Not Specified |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Agt/Agt |
Background: |
involves: 129P2/OlaHsd * C57BL/6J |
Zygosity: |
ht |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Publication |
First Author: |
Kalupahana NS |
Year: |
2012 |
Journal: |
Obesity (Silver Spring) |
Title: |
Overproduction of angiotensinogen from adipose tissue induces adipose inflammation, glucose intolerance, and insulin resistance. |
Volume: |
20 |
Issue: |
1 |
Pages: |
48-56 |
|
•
•
•
•
•
|
Allele |
Name: |
gap junction protein, alpha 1; mutation 1, Janet Rossant |
Allele Type: |
Chemically induced (ENU) |
|
|
•
•
•
•
•
|
Allele |
Name: |
transgene insertion 867, Louis J Ptacek |
Allele Type: |
Transgenic |
Attribute String: |
Humanized sequence, Inserted expressed sequence |
|
•
•
•
•
•
|
Allele |
Name: |
lamin B2; targeted mutation 2, Stephen G Young |
Allele Type: |
Targeted |
|
|
•
•
•
•
•
|
Allele |
Name: |
period circadian clock 2; endonuclease-mediated mutation 2, David Virshup |
Allele Type: |
Endonuclease-mediated |
Attribute String: |
Not Specified |
|
•
•
•
•
•
|
Allele |
Name: |
endoplasmic reticulum to nucleus signalling 1; targeted mutation 2.1, Yong Liu |
Allele Type: |
Targeted |
|
|
•
•
•
•
•
|
Strain |
Attribute String: |
coisogenic, endonuclease-mediated mutation, mutant strain |
|
•
•
•
•
•
|
Publication |
First Author: |
Flenniken AM |
Year: |
2005 |
Journal: |
Development |
Title: |
A Gja1 missense mutation in a mouse model of oculodentodigital dysplasia. |
Volume: |
132 |
Issue: |
19 |
Pages: |
4375-86 |
|
•
•
•
•
•
|
Publication |
First Author: |
Tong D |
Year: |
2009 |
Journal: |
Dis Model Mech |
Title: |
Oogenesis defects in a mutant mouse model of oculodentodigital dysplasia. |
Volume: |
2 |
Issue: |
3-4 |
Pages: |
157-67 |
|
•
•
•
•
•
|
Publication |
First Author: |
Rossant J |
Year: |
2003 |
Journal: |
MGI Direct Data Submission |
Title: |
ENU mutants from the Center of Modeling Human Disease |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Tong D |
Year: |
2009 |
Journal: |
Biol Reprod |
Title: |
A dominant loss-of-function GJA1 (Cx43) mutant impairs parturition in the mouse. |
Volume: |
80 |
Issue: |
6 |
Pages: |
1099-106 |
|
•
•
•
•
•
|
Publication |
First Author: |
Churko JM |
Year: |
2011 |
Journal: |
J Invest Dermatol |
Title: |
The G60S connexin43 mutant regulates hair growth and hair fiber morphology in a mouse model of human oculodentodigital dysplasia. |
Volume: |
131 |
Issue: |
11 |
Pages: |
2197-204 |
|
•
•
•
•
•
|
Publication |
First Author: |
Manias JL |
Year: |
2008 |
Journal: |
Cardiovasc Res |
Title: |
Fate of connexin43 in cardiac tissue harbouring a disease-linked connexin43 mutant. |
Volume: |
80 |
Issue: |
3 |
Pages: |
385-95 |
|
•
•
•
•
•
|
Publication |
First Author: |
Langlois S |
Year: |
2007 |
Journal: |
J Biol Chem |
Title: |
Connexin levels regulate keratinocyte differentiation in the epidermis. |
Volume: |
282 |
Issue: |
41 |
Pages: |
30171-80 |
|
•
•
•
•
•
|
Publication |
First Author: |
Book SA |
Year: |
2023 |
Journal: |
Dev Dyn |
Title: |
Discordant growth of nasal cartilage and bone contributes to phenotypic variability of the skull in a mouse model. |
Volume: |
252 |
Issue: |
7 |
Pages: |
1009-1025 |
|
•
•
•
•
•
|
Publication |
First Author: |
Plante I |
Year: |
2010 |
Journal: |
Biol Reprod |
Title: |
Milk secretion and ejection are impaired in the mammary gland of mice harboring a Cx43 mutant while expression and localization of tight and adherens junction proteins remain unchanged. |
Volume: |
82 |
Issue: |
5 |
Pages: |
837-47 |
|
•
•
•
•
•
|
Publication |
First Author: |
McLachlan E |
Year: |
2008 |
Journal: |
J Bone Miner Res |
Title: |
ODDD-linked Cx43 mutants reduce endogenous Cx43 expression and function in osteoblasts and inhibit late stage differentiation. |
Volume: |
23 |
Issue: |
6 |
Pages: |
928-38 |
|
•
•
•
•
•
|
Publication |
First Author: |
Plante I |
Year: |
2008 |
Journal: |
Dev Biol |
Title: |
Decreased levels of connexin43 result in impaired development of the mammary gland in a mouse model of oculodentodigital dysplasia. |
Volume: |
318 |
Issue: |
2 |
Pages: |
312-22 |
|
•
•
•
•
•
|
Publication |
First Author: |
Winterhager E |
Year: |
2013 |
Journal: |
Biol Reprod |
Title: |
Decidual angiogenesis and placental orientation are altered in mice heterozygous for a dominant loss-of-function Gja1 (connexin43) mutation. |
Volume: |
89 |
Issue: |
5 |
Pages: |
111 |
|
•
•
•
•
•
|
Allele |
Name: |
transgene insertion 1, Michele Teboul |
Allele Type: |
Transgenic |
Attribute String: |
Inserted expressed sequence |
|
•
•
•
•
•
|
Allele |
Name: |
transgene insertion 2, Michele Teboul |
Allele Type: |
Transgenic |
Attribute String: |
Inserted expressed sequence |
|
•
•
•
•
•
|
Allele |
Name: |
transgene insertion 1827/1, Curt Sigmund |
Allele Type: |
Transgenic |
Attribute String: |
Inserted expressed sequence |
|
•
•
•
•
•
|
Allele |
Name: |
transgene insertion 153, Thierry Pedrazzini |
Allele Type: |
Transgenic |
Attribute String: |
Inserted expressed sequence |
|
•
•
•
•
•
|
Allele |
Name: |
transgene insertion 101, Thierry Pedrazzini |
Allele Type: |
Transgenic |
Attribute String: |
Inserted expressed sequence |
|
•
•
•
•
•
|
Strain |
Attribute String: |
congenic, mutant strain, transgenic |
|
•
•
•
•
•
|
Allele |
Name: |
collagen, type II, alpha 1; targeted mutation 1.1, Audrey McAlinden |
Allele Type: |
Targeted |
Attribute String: |
Modified isoform(s) |
|
•
•
•
•
•
|
Allele |
Name: |
ectonucleotide pyrophosphatase/phosphodiesterase 1; b haplotype |
Allele Type: |
Spontaneous |
|
|
•
•
•
•
•
|
Allele |
Name: |
CUGBP, Elav-like family member 1; targeted mutation 1, Nikolai A Timchenko |
Allele Type: |
Targeted |
|
|
•
•
•
•
•
|
Strain |
Attribute String: |
mutant strain, endonuclease-mediated mutation |
|
•
•
•
•
•
|
Allele |
Name: |
angiotensin converting enzyme 2; endonuclease-mediated mutation 2, Channabasavaiah Gurumurthy |
Allele Type: |
Endonuclease-mediated |
Attribute String: |
Humanized sequence |
|
•
•
•
•
•
|
Allele |
Name: |
stimulator of interferon response cGAMP interactor 1; endonuclease-mediated mutation 1, Zhijian Chen |
Allele Type: |
Endonuclease-mediated |
Attribute String: |
Not Specified |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Gja1/Gja1<+> |
Background: |
involves: C3H/HeJ * C57BL/6J |
Zygosity: |
ht |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Gja1/Gja1<+> |
Background: |
involves: C3H/HeJ * C57BL/6J * FVB/N |
Zygosity: |
ht |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Tg(PER2*S662G)867Ljp/? |
Background: |
involves: C57BL/6 |
Zygosity: |
ot |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Lmnb2/Lmnb2 |
Background: |
involves: 129P2/OlaHsd * C57BL/6 |
Zygosity: |
hm |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Publication |
First Author: |
Sakai K |
Year: |
2007 |
Journal: |
J Clin Invest |
Title: |
Local production of angiotensin II in the subfornical organ causes elevated drinking. |
Volume: |
117 |
Issue: |
4 |
Pages: |
1088-95 |
|
•
•
•
•
•
|
Publication |
First Author: |
Agassandian K |
Year: |
2017 |
Journal: |
Am J Physiol Regul Integr Comp Physiol |
Title: |
Evidence for intraventricular secretion of angiotensinogen and angiotensin by the subfornical organ using transgenic mice. |
Volume: |
312 |
Issue: |
6 |
Pages: |
R973-R981 |
|
•
•
•
•
•
|
Publication |
First Author: |
Li H |
Year: |
2016 |
Journal: |
Autophagy |
Title: |
Atg5-mediated autophagy deficiency in proximal tubules promotes cell cycle G2/M arrest and renal fibrosis. |
Volume: |
12 |
Issue: |
9 |
Pages: |
1472-86 |
|
•
•
•
•
•
|
Publication |
First Author: |
Davisson RL |
Year: |
1999 |
Journal: |
Physiol Genomics |
Title: |
Novel mechanism of hypertension revealed by cell-specific targeting of human angiotensinogen in transgenic mice. |
Volume: |
1 |
Issue: |
1 |
Pages: |
3-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Jain S |
Year: |
2008 |
Journal: |
Am J Physiol Regul Integr Comp Physiol |
Title: |
A haplotype of human angiotensinogen gene containing -217A increases blood pressure in transgenic mice compared with -217G. |
Volume: |
295 |
Issue: |
6 |
Pages: |
R1849-57 |
|
•
•
•
•
•
|
Allele |
Name: |
hypoxanthine phosphoribosyltransferase 1; targeted mutation 1, Curt Sigmund |
Allele Type: |
Targeted |
Attribute String: |
Humanized sequence, Inserted expressed sequence |
|
•
•
•
•
•
|
Publication |
First Author: |
Pellieux C |
Year: |
2012 |
Journal: |
Am J Physiol Heart Circ Physiol |
Title: |
Differential effects of high-fat diet on myocardial lipid metabolism in failing and nonfailing hearts with angiotensin II-mediated cardiac remodeling in mice. |
Volume: |
302 |
Issue: |
9 |
Pages: |
H1795-805 |
|
•
•
•
•
•
|
Publication |
First Author: |
Huggins CE |
Year: |
2009 |
Journal: |
Am J Physiol Heart Circ Physiol |
Title: |
Dietary fish oil is antihypertrophic but does not enhance postischemic myocardial function in female mice. |
Volume: |
296 |
Issue: |
4 |
Pages: |
H957-66 |
|
•
•
•
•
•
|
Publication |
First Author: |
Domenighetti AA |
Year: |
2005 |
Journal: |
Hypertension |
Title: |
Angiotensin II-mediated phenotypic cardiomyocyte remodeling leads to age-dependent cardiac dysfunction and failure. |
Volume: |
46 |
Issue: |
2 |
Pages: |
426-32 |
|
•
•
•
•
•
|
Allele |
Name: |
hypoxanthine phosphoribosyltransferase 1; targeted mutation 1, Ashok Kumar |
Allele Type: |
Targeted |
Attribute String: |
Humanized sequence, Inserted expressed sequence |
|
•
•
•
•
•
|
Allele |
Name: |
hypoxanthine phosphoribosyltransferase 1; targeted mutation 2, Ashok Kumar |
Allele Type: |
Targeted |
Attribute String: |
Humanized sequence, Inserted expressed sequence |
|
•
•
•
•
•
|