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Search results 401 to 500 out of 2004 for Arc

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Type Details Score
Publication
10235267 | -
First Author: Näär AM
Year: 1999
Journal: Nature
Title: Composite co-activator ARC mediates chromatin-directed transcriptional activation.
Volume: 398
Issue: 6730
Pages: 828-32
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Protein Coding Gene
MGI:1925938 | Nol3
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
25864631 | -
First Author: Zhang W
Year: 2015
Journal: Neuron
Title: Structural basis of arc binding to synaptic proteins: implications for cognitive disease.
Volume: 86
Issue: 2
Pages: 490-500
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Publication
31080121 | -
First Author: Nielsen LD
Year: 2019
Journal: Structure
Title: The Capsid Domain of Arc Changes Its Oligomerization Propensity through Direct Interaction with the NMDA Receptor.
Volume: 27
Issue: 7
Pages: 1071-1081.e5
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Interaction Experiment
Pastuzyn ED (2017)
Description: Activity-Dependent Arc Expression and Homeostatic Synaptic Plasticity Are Altered in Neurons from a Mouse Model of Angelman Syndrome.
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Publication
36998269 | -
 
First Author: Ghane MA
Year: 2023
Journal: Front Cell Neurosci
Title: Arc ubiquitination regulates endoplasmic reticulum-mediated Ca(2+) release and CaMKII signaling.
Volume: 17
Pages: 1091324
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GXD Expression
GXD Expression
 
Assay Type: In situ reporter (knock in)
Annotation Date: 2005-06-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603917
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:3579494
Age: embryonic day 10.5
Image: 2Aa
Note: Staining is in an arc in the center of the embryo.
Specimen Label: 2Aa
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:26737
Assay Type: RNA in situ
Annotation Date: 2017-01-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1759220
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:5816597
Age: embryonic day 12.5
Note: Expressed in the epidermis lining the internal margin of the pinna, along an arc towards the vestibulocochlear ganglion.
Specimen Label: not shown
Detected: true
Specimen Num: 11
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GO Term
GO:0170047 | virus-like capsid
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Publication
12646376 | -
First Author: Anderson TA
Year: 2003
Journal: Biophys Chem
Title: Role of an N(cap) residue in determining the stability and operator-binding affinity of Arc repressor.
Volume: 100
Issue: 1-3
Pages: 341-50
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GXD Expression
GXD Expression
Probe: MGI:3712749
Assay Type: RNA in situ
Annotation Date: 2007-06-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1614815
Pattern: Regionally restricted
Stage: TS15
Assay Id: MGI:3712750
Age: embryonic day 9.5
Image: 2C
Note: Expression is present in a dorsal to ventral arc at the level of the midbrain-hindbrain junction. This expression is not present in the dorsal midline.
Specimen Label: 2C
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
Probe: MGI:3712749
Assay Type: RNA in situ
Annotation Date: 2007-06-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1614815
Pattern: Regionally restricted
Stage: TS15
Assay Id: MGI:3712750
Age: embryonic day 9.5
Image: 2E
Note: Expression is present in a dorsal to ventral arc at the level of the midbrain-hindbrain junction. This expression is not present in the dorsal midline.
Specimen Label: 2E
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
Probe: MGI:3712749
Assay Type: RNA in situ
Annotation Date: 2007-06-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1614015
Pattern: Regionally restricted
Stage: TS15
Assay Id: MGI:3712750
Age: embryonic day 9.5
Image: 2C
Note: Expression is present in a dorsal to ventral arc at the level of the midbrain-hindbrain junction. This expression is not present in the dorsal midline.
Specimen Label: 2C
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
Probe: MGI:3712749
Assay Type: RNA in situ
Annotation Date: 2007-06-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1614015
Pattern: Regionally restricted
Stage: TS15
Assay Id: MGI:3712750
Age: embryonic day 9.5
Image: 2E
Note: Expression is present in a dorsal to ventral arc at the level of the midbrain-hindbrain junction. This expression is not present in the dorsal midline.
Specimen Label: 2E
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
Probe: MGI:1329444
Assay Type: RNA in situ
Annotation Date: 2001-02-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160589
Pattern: Regionally restricted
Stage: TS09
Assay Id: MGI:1930278
Age: embryonic day 6.5
Image: 5. D
Note: Expression detected in visceral endoderm in an arc of cells spanning the anterior midline including the most proximal region of the anterior visceral endoderm.
Specimen Label: 5. D
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:34186
Assay Type: RNA in situ
Annotation Date: 2013-06-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1724519
Pattern: Regionally restricted
Stage: TS19
Assay Id: MGI:5490998
Age: embryonic day 11.5
Image: 7D
Note: Expression is in an arc of cells that spanned the anterior-posterior axis of the hand/footplate. (Authors did not specify hand or foot is shown)
Specimen Label: 7D
Detected: true
Specimen Num: 10
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GXD Expression
GXD Expression
Probe: MGI:3760108
Assay Type: RNA in situ
Annotation Date: 2007-11-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1758921
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:3760112
Age: embryonic day 13.5
Image: 5C
Note: Expression is present in a discrete band lining the internal margin of the pinna, extending along an arc towards the vestibulocochlear ganglion.
Specimen Label: 5C
Detected: true
Specimen Num: 8
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GXD Expression
GXD Expression
Probe: MGI:3760108
Assay Type: RNA in situ
Annotation Date: 2007-11-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1758921
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:3760112
Age: embryonic day 13.5
Image: 7C
Note: Expression is present in a discrete band lining the internal margin of the pinna, extending along an arc towards the vestibulocochlear ganglion.
Specimen Label: 7C
Detected: true
Specimen Num: 13
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GXD Expression
GXD Expression
Probe: MGI:34186
Assay Type: RNA in situ
Annotation Date: 2013-06-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1724919
Pattern: Regionally restricted
Stage: TS19
Assay Id: MGI:5490998
Age: embryonic day 11.5
Image: 7D
Note: Expression is in an arc of cells that spanned the anterior-posterior axis of the hand/footplate. (Authors did not specify hand or foot is shown)
Specimen Label: 7D
Detected: true
Specimen Num: 10
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GXD Expression
GXD Expression
Probe: MGI:1329444
Assay Type: RNA in situ
Annotation Date: 2001-02-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360689
Pattern: Regionally restricted
Stage: TS09
Assay Id: MGI:1930278
Age: embryonic day 6.5
Image: 5. D
Note: Expression detected in visceral endoderm in an arc of cells spanning the anterior midline including the most proximal region of the anterior visceral endoderm.
Specimen Label: 5. D
Detected: true
Specimen Num: 1
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Allele
Arc<em1(cre/ERT2)Smoc> | MGI:6514766
Name: activity regulated cytoskeletal-associated protein; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Inducible, Recombinase
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Allele
Tg(Arc/EGFP)3Hbto | MGI:7520076
Name: transgene insertion 1, Haruhiko Bito
Allele Type: Transgenic
Attribute String: Inserted expressed sequence, Reporter
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Publication
1311296 | -
First Author: Verhoogt HJ
Year: 1992
Journal: J Bacteriol
Title: arcD, the first gene of the arc operon for anaerobic arginine catabolism in Pseudomonas aeruginosa, encodes an arginine-ornithine exchanger.
Volume: 174
Issue: 5
Pages: 1568-73
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Publication
29445324 | J:290047
 
First Author: Steward O
Year: 2017
Journal: Front Mol Neurosci
Title: Delayed Degradation and Impaired Dendritic Delivery of Intron-Lacking EGFP-Arc/Arg3.1 mRNA in EGFP-Arc Transgenic Mice.
Volume: 10
Pages: 435
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HT Experiment
E-GEOD-83192 | Liver tissue from liver specific Vps33b knockout (Vps33bfl/fl-AlfpCre) and control (Vps33bfl/fl) mice
Series Id: GSE83192
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
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HT Experiment
GSE225038 | Effects of Klf4 deletion from Agrp expressing cells under chow or HFD conditions
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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Strain
MGI:6428190 | C57BL/6JSmoc-Arc<em1(cre/ERT2)Smoc>/Smoc
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
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Allele
Tg(Arc-luc2)1Himo | MGI:7520071
Name: transgene insertion 1, Hisashi Mori
Allele Type: Transgenic
Attribute String: Reporter
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GXD Expression
GXD Expression
Probe: MGI:34186
Assay Type: RNA in situ
Annotation Date: 2013-06-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1640618
Pattern: Regionally restricted
Stage: TS18
Assay Id: MGI:5490998
Age: embryonic day 11.0
Image: 7C
Note: Expression is at the distal edge and in an arc orthogonal to the proximal-distal axis that was broad at the anterior edge and narrowed towards the center of the limb and in a central region.
Specimen Label: 7C
Detected: true
Specimen Num: 9
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HT Experiment
GSE154153 | Single cell RNA-seq of the developing mouse hypothalamus
 
Experiment Type: RNA-Seq
Study Type: Baseline
Source: GEO
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Allele
Arc<tm1Smoc> | MGI:7288322
Name: activity regulated cytoskeletal-associated protein; targeted mutation 1, Shanghai Model Organisms Center
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
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Strain
MGI:6146598 | C57BL/6-Tg(Arc/EGFP)3Hbto/HbtoRbrc
Attribute String: mutant strain, coisogenic, transgenic
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Strain
MGI:6146568 | C57BL/6-Tg(Arc-luc2)1Himo/HimoRbrc
Attribute String: mutant strain, coisogenic, transgenic
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HT Experiment
E-GEOD-68515 | Hippocampal gene expression in aged and young HSD1 knockout mice
Series Id: GSE68515
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
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Protein Domain
IPR005569 | Arc_DNA-bd_dom
Type: Domain
Description: Arc repressor act by the cooperative binding of two Arc repressor dimers to a 21-base-pair operator site. Each Arc dimer uses an antiparallel β-sheet to recognise bases in the major groove [].
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Publication
19059347 | J:256593
First Author: Eguchi M
Year: 2009
Journal: Neuroimage
Title: In vivo and in vitro visualization of gene expression dynamics over extensive areas of the brain.
Volume: 44
Issue: 4
Pages: 1274-83
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Allele
Trpc5<tm1.1Mfre> | MGI:6383454
Name: transient receptor potential cation channel, subfamily C, member 5; targeted mutation 1.1, Marc Freichel
Allele Type: Targeted
Attribute String: Conditional ready, Hypomorph, Reporter
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DO Term
DOID:551 | toxic pneumonitis
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HT Experiment
E-MTAB-9420 | Transcriptome and DNA (hydro)methylation in mouse hypothalamic arcuate nucleus in puberty onset
 
Experiment Type: RNA-Seq
Study Type: Baseline
Source: ArrayExpress
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Allele
Tg(Pomc-dre)#Jcbr | MGI:6828609
Name: transgene insertion, Jens C Bruning
Allele Type: Transgenic
Attribute String: Recombinase
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Allele
Tg(Arc-tTA,-EGFP/Capzb*)10Mkyph | MGI:7344056
Name: transgene insertion 10, Maki Yamada
Allele Type: Transgenic
Attribute String: Inserted expressed sequence, Reporter, Transactivator
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Allele
Tg(Arc-Venus)#Shuny | MGI:7616265
Name: transgene insertion, Shun Yamaguchi
Allele Type: Transgenic
Attribute String: Reporter
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Publication
20190753 | J:162967
First Author: Cullinane AR
Year: 2010
Journal: Nat Genet
Title: Mutations in VIPAR cause an arthrogryposis, renal dysfunction and cholestasis syndrome phenotype with defects in epithelial polarization.
Volume: 42
Issue: 4
Pages: 303-12
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HT Experiment
GSE126480 | Single cell transcriptome analysis of developing arcuate nucleus neurons uncovers their key developmental regulators
 
Experiment Type: RNA-Seq
Study Type: Baseline
Source: GEO
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Publication
29409756 | J:318904
First Author: Rogerson C
Year: 2018
Journal: Biochim Biophys Acta Mol Basis Dis
Title: VPS33B and VIPAR are essential for epidermal lamellar body biogenesis and function.
Volume: 1864
Issue: 5 Pt A
Pages: 1609-1621
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Allele
Arc<tm1.1(cre/ERT2)Luo> | MGI:5488904
Name: activity regulated cytoskeletal-associated protein; targeted mutation 1.1, Liqun Luo
Allele Type: Targeted
Attribute String: Inducible, Recombinase
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Allele
Fos<tm1.1(cre/ERT2)Luo> | MGI:5488905
Name: FBJ osteosarcoma oncogene; targeted mutation 1.1, Liqun Luo
Allele Type: Targeted
Attribute String: Inducible, Recombinase
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Strain
MGI:7507330 | C57BL/6N-Tg(Arc-tTA,-EGFP/Capzb*)10Mkyph/MkyphRbrc
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Strain
MGI:7344057 | B6N.Cg-Tg(Arc-tTA,-EGFP/Capzb*)10Mkyph/J
Attribute String: mutant strain, transgenic, congenic
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Publication
32943708 | J:296392
First Author: Kuboyama K
Year: 2020
Journal: Sci Rep
Title: Traceable stimulus-dependent rapid molecular changes in dendritic spines in the brain.
Volume: 10
Issue: 1
Pages: 15266
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Publication
31285329 | J:277600
First Author: Blum T
Year: 2019
Journal: Proc Natl Acad Sci U S A
Title: Trpc5 deficiency causes hypoprolactinemia and altered function of oscillatory dopamine neurons in the arcuate nucleus.
Volume: 116
Issue: 30
Pages: 15236-15243
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Publication
25947942 | J:222766
First Author: Bem D
Year: 2015
Journal: Blood
Title: VPS33B regulates protein sorting into and maturation of α-granule progenitor organelles in mouse megakaryocytes.
Volume: 126
Issue: 2
Pages: 133-43
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Publication
32103003 | J:286398
First Author: Matsumura K
Year: 2020
Journal: Nat Commun
Title: Pathogenic POGZ mutation causes impaired cortical development and reversible autism-like phenotypes.
Volume: 11
Issue: 1
Pages: 859
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Strain
MGI:5488909 | B6.129(Cg)-Arc<tm1.1(cre/ERT2)Luo>/J
Attribute String: congenic, mutant strain, targeted mutation
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Strain
MGI:5488912 | B6.129(Cg)-Fos<tm1.1(cre/ERT2)Luo>/J
Attribute String: targeted mutation, congenic, mutant strain
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Publication
32144256 | J:287254
First Author: Aqrabawi AJ
Year: 2020
Journal: Nat Commun
Title: Olfactory memory representations are stored in the anterior olfactory nucleus.
Volume: 11
Issue: 1
Pages: 1246
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Publication
37471228 | J:339936
First Author: Park J
Year: 2023
Journal: Cell Rep
Title: Chemogenetic regulation of the TARP-lipid interaction mimics LTP and reversibly modifies behavior.
Volume: 42
Issue: 8
Pages: 112826
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Publication
31171697 | J:277379
First Author: Loureiro M
Year: 2019
Journal: Science
Title: Social transmission of food safety depends on synaptic plasticity in the prefrontal cortex.
Volume: 364
Issue: 6444
Pages: 991-995
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Publication
32668253 | J:312123
First Author: Huang WC
Year: 2020
Journal: Cell Rep
Title: Social Behavior Is Modulated by Valence-Encoding mPFC-Amygdala Sub-circuitry.
Volume: 32
Issue: 2
Pages: 107899
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Genotype
Genotype
Symbol: Fos/Fos<+>
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Arc/Arc
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Zygosity: hm
Has Mutant Allele: true
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HT Experiment
GSE84175 | RNA-seq of hippocampus from wild type and CTCF cko animals
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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Publication
15790593 | J:99274
First Author: Gissen P
Year: 2005
Journal: Hum Mol Genet
Title: Comparative evolutionary analysis of VPS33 homologues: genetic and functional insights.
Volume: 14
Issue: 10
Pages: 1261-70
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Publication
28082148 | J:245616
First Author: Hanley J
Year: 2017
Journal: J Hepatol
Title: Vps33b is crucial for structural and functional hepatocyte polarity.
Volume: 66
Issue: 5
Pages: 1001-1011
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Protein Domain
IPR040814 | Arc_C
Type: Domain
Description: This entry represents the C-terminal capsid-like domain of the Activity-regulated cytoskeleton-associated protein (Arc). The Arc protein modulates the trafficking of AMPA-type glutamate receptors [, ]. The tertiary structure of this two-lobe capsid domain is similar to the capsid domain of HIV gag protein. The domain is thought to have evolved from the capsid domain of Ty3/Gypsy retrotransposon [, ].
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Protein Domain
IPR045557 | Arc_N
Type: Domain
Description: This entry represents the N-terminal matrix-like (MA) domain of the Activity-Regulated Cytoskeleton-Associated protein (Arc). This domain might be involved in stabilising the relative domain orientations of the capside-like domain (CA) upon capsid assembly []. Arc is a regulator of synaptic scaling and dendrite remodelling [].
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Publication
23389689 | J:263351
First Author: Takao K
Year: 2013
Journal: Neuropsychopharmacology
Title: Deficiency of schnurri-2, an MHC enhancer binding protein, induces mild chronic inflammation in the brain and confers molecular, neuronal, and behavioral phenotypes related to schizophrenia.
Volume: 38
Issue: 8
Pages: 1409-25
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Publication
35797997 | J:332339
First Author: Serrano M
Year: 2022
Journal: Curr Biol
Title: Strategy updating mediated by specific retrosplenial-parafascicular-basal ganglia networks.
Volume: 32
Issue: 16
Pages: 3477-3492.e5
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Publication
30297716 | J:267581
First Author: Chowdhury A
Year: 2018
Journal: Nat Commun
Title: Time units for learning involving maintenance of system-wide cFos expression in neuronal assemblies.
Volume: 9
Issue: 1
Pages: 4122
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Publication
30655440 | J:273335
First Author: Corder G
Year: 2019
Journal: Science
Title: An amygdalar neural ensemble that encodes the unpleasantness of pain.
Volume: 363
Issue: 6424
Pages: 276-281
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Genotype
Genotype
Symbol: 7630403G23Rik/7630403G23Rik<+> Trpc5/Trpc5
Background: involves: 129S1/Sv * 129S4/SvJaeSor * 129X1/SvJ * C57BL/6N * SJL
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Pomc-dre)#Jcbr/?
Background: involves: C57BL/6
Zygosity: cn
Has Mutant Allele: true
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Publication
25448678 | J:216946
First Author: Maejima Y
Year: 2014
Journal: FEBS Lett
Title: Oxytocinergic circuit from paraventricular and supraoptic nuclei to arcuate POMC neurons in hypothalamus.
Volume: 588
Issue: 23
Pages: 4404-12
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Publication
12562822 | -
First Author: Pedulla ML
Year: 2003
Journal: J Bacteriol
Title: Corrected sequence of the bacteriophage p22 genome.
Volume: 185
Issue: 4
Pages: 1475-7
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Publication
6350606 | -
First Author: Sauer RT
Year: 1983
Journal: J Mol Biol
Title: Primary structure of the immI immunity region of bacteriophage P22.
Volume: 168
Issue: 4
Pages: 699-713
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Protein Domain
IPR018875 | Antirepressor_Ant_N
Type: Domain
Description: The Antirepressor protein ant from Salmonella phage P22 prevents the prophage p22 c2 repressor protein from binding to its operators. It also inhibits the action of other prophage repressor proteins, including those of phages lambda and 434. The synthesis of antirepressor is negatively regulated by the protein products of the two other immi genes, mnt and arc [, , ]. This entry represents the N-terminal domain of this protein and similar proteins from tailed bacteriophages (Caudovirales) and bacterial prophages mostly found in Proteobacteria.
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Publication
15383280 | J:217283
First Author: Nam YJ
Year: 2004
Journal: Mol Cell
Title: Inhibition of both the extrinsic and intrinsic death pathways through nonhomotypic death-fold interactions.
Volume: 15
Issue: 6
Pages: 901-12
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Publication
15312650 | J:96571
First Author: Kanai Y
Year: 2004
Journal: Neuron
Title: Kinesin transports RNA: isolation and characterization of an RNA-transporting granule.
Volume: 43
Issue: 4
Pages: 513-25
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Publication
24177210 | J:208303
 
First Author: Niimi K
Year: 2014
Journal: Behav Brain Res
Title: Blockade of Cav2.1-mediated NMDA receptor signaling disrupts conditioned fear extinction.
Volume: 259
Pages: 45-9
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Publication
26841680 | J:236280
 
First Author: Dubeykovskaya Z
Year: 2016
Journal: Nat Commun
Title: Neural innervation stimulates splenic TFF2 to arrest myeloid cell expansion and cancer.
Volume: 7
Pages: 10517
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Publication
9512393 | J:103598
First Author: Steward O
Year: 1998
Journal: Neuroreport
Title: No evidence for disruption of normal patterns of mRNA localization in dendrites or dendritic transport of recently synthesized mRNA in FMR1 knockout mice, a model for human fragile-X mental retardation syndrome.
Volume: 9
Issue: 3
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