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Search results 401 to 486 out of 486 for Aurkb

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Type Details Score
Publication
14681479 | J:122989
First Author: Visel A
Year: 2004
Journal: Nucleic Acids Res
Title: GenePaint.org: an atlas of gene expression patterns in the mouse embryo.
Volume: 32
Issue: Database issue
Pages: D552-6
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Publication
34321999 | J:313619
 
First Author: Bedogni F
Year: 2021
Journal: Front Mol Neurosci
Title: Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development.
Volume: 14
Pages: 686034
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Publication
18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
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Publication
- | J:157065
     
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
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Publication
- | J:155856
       
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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UniProt Feature
UniProt Feature
Begin: 117
Description: Phosphothreonine; by AURKB
Type: modified residue
End: 117
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UniProt Feature
UniProt Feature
Begin: 210
Description: Phosphoserine; by AURKB
Type: modified residue
End: 210
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UniProt Feature
UniProt Feature
Begin: 388
Description: Phosphoserine; by AURKB
Type: modified residue
End: 388
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UniProt Feature
UniProt Feature
Begin: 411
Description: Phosphoserine; by AURKB
Type: modified residue
End: 411
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UniProt Feature
UniProt Feature
Begin: 266
Description: Phosphoserine; by AURKB
Type: modified residue
End: 266
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UniProt Feature
UniProt Feature
Begin: 180
Description: Phosphoserine; by AURKB
Type: modified residue
End: 180
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UniProt Feature
UniProt Feature
Begin: 281
Description: Phosphothreonine; by AURKB
Type: modified residue
End: 281
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UniProt Feature
UniProt Feature
Begin: 92
Description: Phosphoserine; by AURKB
Type: modified residue
End: 92
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UniProt Feature
UniProt Feature
Begin: 860
Description: Phosphothreonine; by AURKB
Type: modified residue
End: 860
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UniProt Feature
UniProt Feature
Begin: 139
Description: Phosphoserine; by AURKB
Type: modified residue
End: 139
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UniProt Feature
UniProt Feature
Begin: 12
Description: Phosphoserine; by AURKB
Type: modified residue
End: 12
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UniProt Feature
UniProt Feature
Begin: 60
Description: Phosphoserine; by AURKB
Type: modified residue
End: 60
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UniProt Feature
UniProt Feature
Begin: 314
Description: Phosphoserine; by AURKB
Type: modified residue
End: 314
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UniProt Feature
UniProt Feature
Begin: 306
Description: Phosphoserine; by AURKB
Type: modified residue
End: 306
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UniProt Feature
UniProt Feature
Begin: 12
Description: Phosphoserine; by AURKB and ROCK1
Type: modified residue
End: 12
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UniProt Feature
UniProt Feature
Begin: 35
Description: Phosphoserine; by AURKB and ROCK1
Type: modified residue
End: 35
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UniProt Feature
UniProt Feature
Begin: 7
Description: Phosphothreonine; by AURKB and ROCK1
Type: modified residue
End: 7
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UniProt Feature
UniProt Feature
Begin: 17
Description: Phosphothreonine; by AURKB and ROCK1
Type: modified residue
End: 17
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UniProt Feature
UniProt Feature
Begin: 72
Description: Phosphoserine; by AURKB and ROCK2
Type: modified residue
End: 72
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GXD Expression
GXD Expression
Probe: MGI:6400551
Assay Type: Immunohistochemistry
Annotation Date: 2020-03-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284220
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:6400589
Age: embryonic day 12.5
Image: 6E
Note: Virtually no cleaved Casp3+ cells were positively stained with Aurkb (2.1%).
Specimen Label: 6E
Detected: true
Specimen Num: 8
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Allele
Tg(B4galt1-Aurkb)1Saco | MGI:3822832
Name: transgene insertion 1, Paolo Sassone-Corsi
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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GXD Expression
GXD Expression
Probe: MGI:6383856
Assay Type: Immunohistochemistry
Annotation Date: 2020-03-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284220
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:6400915
Age: embryonic day 12.5
Image: 6C
Note: Quantification of cells with G2-specific Aurkb staining in the E12 mutant pallium revealed that 14.4% of Trp53-upregulating cells were in G2 phase, a significantly lower percentage than expected.
Specimen Label: 6C
Detected: true
Specimen Num: 7
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Allele
Aurkb<tm1.1(cre/ERT2)Deli> | MGI:6758108
Name: aurora kinase B; targeted mutation 1.1, Deqiang Li
Allele Type: Targeted
Attribute String: Inducible, Null/knockout, Recombinase, Reporter
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Genotype
Genotype
Symbol: Tg(B4galt1-Aurkb)1Saco/?
Background: involves: 129/Sv * C57BL/6J * SJL
Zygosity: ot
Has Mutant Allele: true
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Transgene
MGI:3656024 | Tg(tetO-Aurkb,lacZ)41Kra
Type: transgene
Organism: mouse, laboratory
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Allele
Tg(B4galt1-Aurkb*K111R*L323I)1Saco | MGI:3822833
Name: transgene insertion 1, Paolo Sassone-Corsi
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Genotype
Genotype
Symbol: Aurkb/Aurkb<+>
Background: Not Specified
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(B4galt1-Aurkb*K111R*L323I)1Saco/?
Background: involves: 129/Sv * C57BL/6J * SJL
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Aurkb/Aurkb<+> Gt(ROSA)26Sor/Gt(ROSA)26Sor<+>
Background: involves: 129X1/SvJ
Zygosity: cn
Has Mutant Allele: true
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Publication
15890684 | J:104239
First Author: Nguyen HG
Year: 2005
Journal: Blood
Title: Conditional overexpression of transgenes in megakaryocytes and platelets in vivo.
Volume: 106
Issue: 5
Pages: 1559-64
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Publication
12925766 | -
First Author: Honda R
Year: 2003
Journal: Mol Biol Cell
Title: Exploring the functional interactions between Aurora B, INCENP, and survivin in mitosis.
Volume: 14
Issue: 8
Pages: 3325-41
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Publication
27332895 | -
First Author: Sasai K
Year: 2016
Journal: PLoS One
Title: Aurora-C Interactions with Survivin and INCENP Reveal Shared and Distinct Features Compared with Aurora-B Chromosome Passenger Protein Complex.
Volume: 11
Issue: 6
Pages: e0157305
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Publication
11139336 | -
First Author: Wheatley SP
Year: 2001
Journal: Exp Cell Res
Title: INCENP binds directly to tubulin and requires dynamic microtubules to target to the cleavage furrow.
Volume: 262
Issue: 2
Pages: 122-7
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Protein Domain
IPR039130 | INCENP
Type: Family
Description: Inner centromere protein (INCENP) is a component of the chromosomal passenger complex (CPC), which is an important regulator of mitosis. CPC ensures correct alignment and segregation of chromosomes at the centromere. INCENT interacts with several other CPC subunits [, , ]and it activates subunits AURKB and AURKC []; it also interacts with the tubulin beta chain []. Two paralogues exist in Xenopus named INCEP A and B.
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Publication
31130069 | J:277690
First Author: Williams MM
Year: 2019
Journal: Cell Cycle
Title: Aurora kinase B-phosphorylated HP1α functions in chromosomal instability.
Volume: 18
Issue: 12
Pages: 1407-1421
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Publication
30245026 | J:294392
 
First Author: Fan K
Year: 2019
Journal: J Autoimmun
Title: CRL4DCAF2 is required for mature T-cell expansion via Aurora B-regulated proteasome activity.
Volume: 96
Pages: 74-85
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Publication
20519624 | J:164528
First Author: den Hollander J
Year: 2010
Journal: Blood
Title: Aurora kinases A and B are up-regulated by Myc and are essential for maintenance of the malignant state.
Volume: 116
Issue: 9
Pages: 1498-505
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Publication
33901174 | J:307094
First Author: Blengini CS
Year: 2021
Journal: PLoS Genet
Title: Aurora kinase A is essential for meiosis in mouse oocytes.
Volume: 17
Issue: 4
Pages: e1009327
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Publication
33510150 | J:302130
First Author: Lin H
Year: 2021
Journal: Nat Commun
Title: Hyperpolyploidization of hepatocyte initiates preneoplastic lesion formation in the liver.
Volume: 12
Issue: 1
Pages: 645
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Publication
27159561 | J:331732
First Author: Devaiah BN
Year: 2016
Journal: Nat Struct Mol Biol
Title: BRD4 is a histone acetyltransferase that evicts nucleosomes from chromatin.
Volume: 23
Issue: 6
Pages: 540-8
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Protein
A0A494B9T7
Organism: Mus musculus/domesticus
Length: 138  
Fragment?: true
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Protein
A0A494BAW4
Organism: Mus musculus/domesticus
Length: 172  
Fragment?: true
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Publication
15316025 | -
First Author: Li X
Year: 2004
Journal: J Biol Chem
Title: Direct association with inner centromere protein (INCENP) activates the novel chromosomal passenger protein, Aurora-C.
Volume: 279
Issue: 45
Pages: 47201-11
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Publication
29462287 | J:285766
First Author: Lian G
Year: 2019
Journal: Cereb Cortex
Title: Cytoskeletal Associated Filamin A and RhoA Affect Neural Progenitor Specification During Mitosis.
Volume: 29
Issue: 3
Pages: 1280-1290
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Publication
25315835 | J:218296
First Author: Nguyen AL
Year: 2014
Journal: J Cell Sci
Title: Phosphorylation of threonine 3 on histone H3 by haspin kinase is required for meiosis I in mouse oocytes.
Volume: 127
Issue: Pt 23
Pages: 5066-78
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Protein
Q9WU62
Organism: Mus musculus/domesticus
Length: 880  
Fragment?: false
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Publication
23581231 | -
First Author: Zekri A
Year: 2012
Journal: Oncol Res
Title: Gene amplification and overexpression of Aurora-C in breast and prostate cancer cell lines.
Volume: 20
Issue: 5-6
Pages: 241-50
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Publication
24603334 | -
 
First Author: Lin BW
Year: 2014
Journal: Cell Death Dis
Title: Overexpression of Aurora-C interferes with the spindle checkpoint by promoting the degradation of Aurora-B.
Volume: 5
Pages: e1106
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Protein Domain
IPR030613 | AURKC
Type: Family
Description: Aurora kinase C (AURKC) is a serine/threonine-protein kinase found in some mammals. It is a component of the chromosomal passenger protein that forms complexes with Aurora-B and inner centromere protein (INCENP), and it has redundant cellular functions with AURKB []. It is required for spermatogenesis and oocyte development [, ]. The overexpression of AURKC has been linked to various cancers []. Overexpression of Aurora-C displaces the centromeric localisation of chromosomal passenger complex (CPC) proteins, including Aurora-B []. CPC plays a crucial role in controlling accurate chromosome segregation and cytokinesis during cell division.The Aurora kinases are highly conserved serine/threonine kinases that regulate chromosomal alignment and segregation during mitosis and meiosis. Three mammalian Aurora kinases, Aurora A, B and C, have been identified. They all contain a protein kinase domain and a destruction box (D-box) recognised by the multi-subunit E3-ubiquitin ligase anaphase promoting complex/cyclosome (APC/C), which mediates their proteasomal degradation. However, their N-terminal domain share little sequence identity and confer unique protein-protein interaction abilities among the Aurora kinases []. They are differentially expressed at high levels in rapidly dividing tissues such as hematopoietic cells (A and B) and germ cells (C only). Their expression is low or absent in most adult tissues due to their lower rates of proliferation [].
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Publication
30107230 | J:318527
 
First Author: Liang S
Year: 2018
Journal: Gene
Title: Identification of Skt11-regulated genes in chondrocytes by integrated bioinformatics analysis.
Volume: 677
Pages: 340-348
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Protein
A0A140LJ30
Organism: Mus musculus/domesticus
Length: 105  
Fragment?: false
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Protein
A0A140LIP1
Organism: Mus musculus/domesticus
Length: 146  
Fragment?: true
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Protein
O88445
Organism: Mus musculus/domesticus
Length: 276  
Fragment?: false
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Protein
E9QL04
Organism: Mus musculus/domesticus
Length: 315  
Fragment?: false
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Protein
Q497X5
Organism: Mus musculus/domesticus
Length: 308  
Fragment?: true
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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