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Search results 401 to 500 out of 543 for Bad

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Hits by Pathway

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Hits by Strain

Type Details Score
Protein Coding Gene
MGI:894689 | Ywhae
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:109484 | Ywhaz
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1891917 | Ywhab
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein
Q9CQV8
Organism: Mus musculus/domesticus
Length: 246  
Fragment?: false
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Protein
P62259
Organism: Mus musculus/domesticus
Length: 255  
Fragment?: false
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Protein
P63101
Organism: Mus musculus/domesticus
Length: 245  
Fragment?: false
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Protein
P97783
Organism: Mus musculus/domesticus
Length: 90  
Fragment?: false
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Protein
Q543U0
Organism: Mus musculus/domesticus
Length: 90  
Fragment?: false
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Publication
10339565 | J:71874
First Author: Sun H
Year: 1999
Journal: Proc Natl Acad Sci U S A
Title: PTEN modulates cell cycle progression and cell survival by regulating phosphatidylinositol 3,4,5,-trisphosphate and Akt/protein kinase B signaling pathway.
Volume: 96
Issue: 11
Pages: 6199-204
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Publication
29786068 | J:301633
First Author: Ma Q
Year: 2019
Journal: Cell Death Differ
Title: Mitochondrial PIP3-binding protein FUNDC2 supports platelet survival via AKT signaling pathway.
Volume: 26
Issue: 2
Pages: 321-331
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Publication
25448064 | J:220285
 
First Author: Kapodistria K
Year: 2015
Journal: Mol Cell Endocrinol
Title: Nephrin, a transmembrane protein, is involved in pancreatic beta-cell survival signaling.
Volume: 400
Pages: 112-28
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Publication
34376666 | J:314346
First Author: Maurizy C
Year: 2021
Journal: Nat Commun
Title: The HSP90/R2TP assembly chaperone promotes cell proliferation in the intestinal epithelium.
Volume: 12
Issue: 1
Pages: 4810
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Publication
12433363 | J:93139
First Author: Khaled AR
Year: 2002
Journal: Immunity
Title: Bax deficiency partially corrects interleukin-7 receptor alpha deficiency.
Volume: 17
Issue: 5
Pages: 561-73
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Publication
12679717 | J:257104
First Author: Herrmann O
Year: 2003
Journal: J Cereb Blood Flow Metab
Title: Regulation of body temperature and neuroprotection by endogenous interleukin-6 in cerebral ischemia.
Volume: 23
Issue: 4
Pages: 406-15
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Publication
22434934 | J:259538
First Author: Kim W
Year: 2012
Journal: Sci Signal
Title: Cannabinoids induce pancreatic β-cell death by directly inhibiting insulin receptor activation.
Volume: 5
Issue: 216
Pages: ra23
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Publication
36477656 | J:332124
First Author: Flanagan DJ
Year: 2022
Journal: Nat Commun
Title: Epithelial TGFβ engages growth-factor signalling to circumvent apoptosis and drive intestinal tumourigenesis with aggressive features.
Volume: 13
Issue: 1
Pages: 7551
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Publication
28753606 | J:244004
First Author: Ruiz R
Year: 2017
Journal: PLoS Genet
Title: The RhoJ-BAD signaling network: An Achilles' heel for BRAF mutant melanomas.
Volume: 13
Issue: 7
Pages: e1006913
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Publication
32001105 | J:347523
First Author: Bogner C
Year: 2020
Journal: Mol Cell
Title: Allosteric Regulation of BH3 Proteins in Bcl-x(L) Complexes Enables Switch-like Activation of Bax.
Volume: 77
Issue: 4
Pages: 901-912.e9
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Publication
31712603 | J:281593
First Author: Fazilaty H
Year: 2019
Journal: Nat Commun
Title: A gene regulatory network to control EMT programs in development and disease.
Volume: 10
Issue: 1
Pages: 5115
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Publication
17052454 | J:114403
First Author: Walensky LD
Year: 2006
Journal: Mol Cell
Title: A stapled BID BH3 helix directly binds and activates BAX.
Volume: 24
Issue: 2
Pages: 199-210
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Publication
19062087 | J:175148
First Author: Lovell JF
Year: 2008
Journal: Cell
Title: Membrane binding by tBid initiates an ordered series of events culminating in membrane permeabilization by Bax.
Volume: 135
Issue: 6
Pages: 1074-84
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Publication
17890680 | J:129992
First Author: Namgaladze D
Year: 2008
Journal: J Lipid Res
Title: Oxidized LDL attenuates apoptosis in monocytic cells by activating ERK signaling.
Volume: 49
Issue: 1
Pages: 58-65
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Publication
19124748 | J:143486
First Author: Ajjappala BS
Year: 2009
Journal: J Immunol
Title: 14-3-3 gamma is stimulated by IL-3 and promotes cell proliferation.
Volume: 182
Issue: 2
Pages: 1050-60
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Publication
19703413 | J:153531
First Author: Matheny RW Jr
Year: 2009
Journal: Biochem Biophys Res Commun
Title: Role of Akt isoforms in IGF-I-mediated signaling and survival in myoblasts.
Volume: 389
Issue: 1
Pages: 117-21
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Publication
25640178 | J:222889
First Author: Ljubicic S
Year: 2015
Journal: Cell Rep
Title: Phospho-BAD BH3 mimicry protects β cells and restores functional β cell mass in diabetes.
Volume: 10
Issue: 4
Pages: 497-504
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Publication
35543624 | J:324543
   
First Author: Jacquemin G
Year: 2022
Journal: Elife
Title: Paracrine signalling between intestinal epithelial and tumour cells induces a regenerative programme.
Volume: 11
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Publication
22538851 | J:188645
First Author: Mérino D
Year: 2012
Journal: Blood
Title: Bcl-2, Bcl-x(L), and Bcl-w are not equivalent targets of ABT-737 and navitoclax (ABT-263) in lymphoid and leukemic cells.
Volume: 119
Issue: 24
Pages: 5807-16
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Publication
15550399 | J:96863
First Author: Day CL
Year: 2005
Journal: J Biol Chem
Title: Solution structure of prosurvival Mcl-1 and characterization of its binding by proapoptotic BH3-only ligands.
Volume: 280
Issue: 6
Pages: 4738-44
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Publication
17476689 | J:153319
First Author: Bohensky J
Year: 2007
Journal: J Cell Physiol
Title: PIM-2 is an independent regulator of chondrocyte survival and autophagy in the epiphyseal growth plate.
Volume: 213
Issue: 1
Pages: 246-51
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Publication
9122213 | J:39329
First Author: Araki R
Year: 1997
Journal: Proc Natl Acad Sci U S A
Title: Nonsense mutation at Tyr-4046 in the DNA-dependent protein kinase catalytic subunit of severe combined immune deficiency mice.
Volume: 94
Issue: 6
Pages: 2438-43
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Publication
10529400 | J:58184
First Author: Fujita E
Year: 1999
Journal: Biochem Biophys Res Commun
Title: Akt phosphorylation site found in human caspase-9 is absent in mouse caspase-9.
Volume: 264
Issue: 2
Pages: 550-5
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Publication
12897128 | J:84802
First Author: Cotteret S
Year: 2003
Journal: Mol Cell Biol
Title: p21-Activated kinase 5 (Pak5) localizes to mitochondria and inhibits apoptosis by phosphorylating BAD.
Volume: 23
Issue: 16
Pages: 5526-39
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Publication
22570335 | J:323793
First Author: Cifarelli V
Year: 2012
Journal: Mol Endocrinol
Title: FOXO1 mediates the autocrine effect of endothelin-1 on endothelial cell survival.
Volume: 26
Issue: 7
Pages: 1213-24
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Publication
21216283 | J:170661
First Author: Boppart MD
Year: 2011
Journal: Biochim Biophys Acta
Title: Activation of AKT signaling promotes cell growth and survival in α7β1 integrin-mediated alleviation of muscular dystrophy.
Volume: 1812
Issue: 4
Pages: 439-46
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Publication
22403441 | J:184083
First Author: Qi Q
Year: 2012
Journal: J Immunol
Title: A unique role for ITK in survival of invariant NKT cells associated with the p53-dependent pathway in mice.
Volume: 188
Issue: 8
Pages: 3611-9
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Publication
15033273 | J:89344
First Author: Nathan BP
Year: 2004
Journal: Behav Brain Res
Title: Olfactory function in apoE knockout mice.
Volume: 150
Issue: 1-2
Pages: 1-7
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Publication
30364284 | J:313200
 
First Author: Tosello Boari J
Year: 2018
Journal: Front Immunol
Title: IL-17RA-Signaling Modulates CD8+ T Cell Survival and Exhaustion During Trypanosoma cruzi Infection.
Volume: 9
Pages: 2347
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Publication
12114718 | J:51465
First Author: Kulig E
Year: 1998
Journal: Endocr Pathol
Title: Remodeling of Hyperplastic Pituitaries in Hypothyroid us-Subunit Knockout Mice After Thyroxine and 1713-Estradiol Treatment: Role of Apoptosis.
Volume: 9
Issue: 3
Pages: 261-274
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Publication
27102962 | J:247155
First Author: Babaev VR
Year: 2016
Journal: Arterioscler Thromb Vasc Biol
Title: Jnk1 Deficiency in Hematopoietic Cells Suppresses Macrophage Apoptosis and Increases Atherosclerosis in Low-Density Lipoprotein Receptor Null Mice.
Volume: 36
Issue: 6
Pages: 1122-31
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Publication
24376837 | J:209846
First Author: Pascucci T
Year: 2013
Journal: PLoS One
Title: Behavioral and neurochemical characterization of new mouse model of hyperphenylalaninemia.
Volume: 8
Issue: 12
Pages: e84697
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Publication
21367852 | J:171123
First Author: Kodama T
Year: 2011
Journal: J Biol Chem
Title: BH3-only activator proteins Bid and Bim are dispensable for Bak/Bax-dependent thrombocyte apoptosis induced by Bcl-xL deficiency: molecular requisites for the mitochondrial pathway to apoptosis in platelets.
Volume: 286
Issue: 16
Pages: 13905-13
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Publication
22692505 | J:189090
First Author: Chang KH
Year: 2012
Journal: Blood
Title: Vav3 collaborates with p190-BCR-ABL in lymphoid progenitor leukemogenesis, proliferation, and survival.
Volume: 120
Issue: 4
Pages: 800-11
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Publication
17607361 | J:124208
First Author: Berquin IM
Year: 2007
Journal: J Clin Invest
Title: Modulation of prostate cancer genetic risk by omega-3 and omega-6 fatty acids.
Volume: 117
Issue: 7
Pages: 1866-75
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Publication
21924230 | J:177374
First Author: Martin GR
Year: 2011
Journal: Am J Pathol
Title: Endogenous prion protein attenuates experimentally induced colitis.
Volume: 179
Issue: 5
Pages: 2290-301
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Publication
20150557 | J:172263
First Author: Yancey PG
Year: 2010
Journal: Arterioscler Thromb Vasc Biol
Title: Macrophage LRP-1 controls plaque cellularity by regulating efferocytosis and Akt activation.
Volume: 30
Issue: 4
Pages: 787-95
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Publication
21771724 | J:176434
First Author: Sun H
Year: 2011
Journal: Carcinogenesis
Title: Omega-3 fatty acids induce apoptosis in human breast cancer cells and mouse mammary tissue through syndecan-1 inhibition of the MEK-Erk pathway.
Volume: 32
Issue: 10
Pages: 1518-24
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Publication
24713656 | J:212762
First Author: Amato KR
Year: 2014
Journal: J Clin Invest
Title: Genetic and pharmacologic inhibition of EPHA2 promotes apoptosis in NSCLC.
Volume: 124
Issue: 5
Pages: 2037-49
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Publication
33594777 | J:342689
First Author: Xu Y
Year: 2021
Journal: Cell Prolif
Title: Farnesoid X receptor promotes renal ischaemia-reperfusion injury by inducing tubular epithelial cell apoptosis.
Volume: 54
Issue: 4
Pages: e13005
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Publication
17327400 | J:145427
First Author: Hu YL
Year: 2007
Journal: Blood
Title: Evidence that the Pim1 kinase gene is a direct target of HOXA9.
Volume: 109
Issue: 11
Pages: 4732-8
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Publication
11792727 | J:73910
First Author: Hogenboom S
Year: 2002
Journal: J Lipid Res
Title: Absence of functional peroxisomes does not lead to deficiency of enzymes involved in cholesterol biosynthesis.
Volume: 43
Issue: 1
Pages: 90-8
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Publication
29295820 | J:257644
First Author: Lee JM
Year: 2018
Journal: J Lipid Res
Title: Diet1, bile acid diarrhea, and FGF15/19: mouse model and human genetic variants.
Volume: 59
Issue: 3
Pages: 429-438
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Publication
18640270 | J:144608
First Author: Yang Q
Year: 2008
Journal: Matrix Biol
Title: VEGF enhancement of osteoclast survival and bone resorption involves VEGF receptor-2 signaling and beta3-integrin.
Volume: 27
Issue: 7
Pages: 589-99
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Publication
11884367 | J:131696
First Author: Baines CP
Year: 2002
Journal: Circ Res
Title: Mitochondrial PKCepsilon and MAPK form signaling modules in the murine heart: enhanced mitochondrial PKCepsilon-MAPK interactions and differential MAPK activation in PKCepsilon-induced cardioprotection.
Volume: 90
Issue: 4
Pages: 390-7
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Publication
16043490 | J:102152
First Author: Kaiser RA
Year: 2005
Journal: J Biol Chem
Title: Genetic inhibition or activation of JNK1/2 protects the myocardium from ischemia-reperfusion-induced cell death in vivo.
Volume: 280
Issue: 38
Pages: 32602-8
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Publication
23670294 | J:201846
First Author: Harb JG
Year: 2013
Journal: Leukemia
Title: Bcl-xL anti-apoptotic network is dispensable for development and maintenance of CML but is required for disease progression where it represents a new therapeutic target.
Volume: 27
Issue: 10
Pages: 1996-2005
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Publication
25266363 | J:253993
First Author: Chatterjee M
Year: 2014
Journal: Circ Res
Title: Macrophage migration inhibitory factor limits activation-induced apoptosis of platelets via CXCR7-dependent Akt signaling.
Volume: 115
Issue: 11
Pages: 939-49
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Publication
18037896 | J:130400
First Author: Muraski JA
Year: 2007
Journal: Nat Med
Title: Pim-1 regulates cardiomyocyte survival downstream of Akt.
Volume: 13
Issue: 12
Pages: 1467-75
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Publication
21173257 | J:169005
First Author: Hirai T
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Parathyroid hormone/parathyroid hormone-related protein receptor signaling is required for maintenance of the growth plate in postnatal life.
Volume: 108
Issue: 1
Pages: 191-6
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Publication
12196559 | J:78748
First Author: Stein TD
Year: 2002
Journal: J Neurosci
Title: Lack of neurodegeneration in transgenic mice overexpressing mutant amyloid precursor protein is associated with increased levels of transthyretin and the activation of cell survival pathways.
Volume: 22
Issue: 17
Pages: 7380-8
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Publication
20075332 | J:170874
First Author: Kimura TE
Year: 2010
Journal: Circ Res
Title: Targeted deletion of the extracellular signal-regulated protein kinase 5 attenuates hypertrophic response and promotes pressure overload-induced apoptosis in the heart.
Volume: 106
Issue: 5
Pages: 961-70
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Publication
19535330 | J:153453
First Author: Pastor MD
Year: 2009
Journal: J Biol Chem
Title: mTOR/S6 kinase pathway contributes to astrocyte survival during ischemia.
Volume: 284
Issue: 33
Pages: 22067-78
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Publication
14522908 | J:86074
First Author: Andarawewa KL
Year: 2003
Journal: Cancer Res
Title: Dual stromelysin-3 function during natural mouse mammary tumor virus-ras tumor progression.
Volume: 63
Issue: 18
Pages: 5844-9
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Publication
34302028 | J:308632
First Author: Liot S
Year: 2021
Journal: Sci Rep
Title: Development of thymic tumor in [LSL:KrasG12D; Pdx1-CRE] mice, an adverse effect associated with accelerated pancreatic carcinogenesis.
Volume: 11
Issue: 1
Pages: 15075
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Publication
25830089 | J:223517
First Author: Patel D
Year: 2015
Journal: Mol Metab
Title: Clic4, a novel protein that sensitizes β-cells to apoptosis.
Volume: 4
Issue: 4
Pages: 253-64
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Publication
26993069 | J:249493
First Author: Park SH
Year: 2016
Journal: Diabetes
Title: IKKβ Is Essential for Adipocyte Survival and Adaptive Adipose Remodeling in Obesity.
Volume: 65
Issue: 6
Pages: 1616-29
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Publication
22451662 | J:185445
First Author: Liu C
Year: 2012
Journal: J Biol Chem
Title: Reduction of Na/K-ATPase potentiates marinobufagenin-induced cardiac dysfunction and myocyte apoptosis.
Volume: 287
Issue: 20
Pages: 16390-8
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Publication
18034420 | J:128528
First Author: Pargmann D
Year: 2007
Journal: Eur J Immunol
Title: Differential impact of the transcriptional repressor Gfi1 on mature CD4+ and CD8+ T lymphocyte function.
Volume: 37
Issue: 12
Pages: 3551-63
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Publication
35238776 | J:321889
   
First Author: Terpollili NA
Year: 2022
Journal: Elife
Title: CaV2.1 channel mutations causing familial hemiplegic migraine type 1 increase the susceptibility for cortical spreading depolarizations and seizures and worsen outcome after experimental traumatic brain injury.
Volume: 11
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Publication
19221220 | J:166007
First Author: Wu JS
Year: 2009
Journal: Circulation
Title: Ligand-activated peroxisome proliferator-activated receptor-gamma protects against ischemic cerebral infarction and neuronal apoptosis by 14-3-3 epsilon upregulation.
Volume: 119
Issue: 8
Pages: 1124-34
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Publication
27122612 | J:249562
First Author: Puthia M
Year: 2016
Journal: Sci Transl Med
Title: IRF7 inhibition prevents destructive innate immunity-A target for nonantibiotic therapy of bacterial infections.
Volume: 8
Issue: 336
Pages: 336ra59
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Publication
12890698 | J:84698
First Author: Simon MT
Year: 2003
Journal: FASEB J
Title: HIP/PAP stimulates liver regeneration after partial hepatectomy and combines mitogenic and anti-apoptotic functions through the PKA signaling pathway.
Volume: 17
Issue: 11
Pages: 1441-50
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Publication
19667098 | J:151850
First Author: Wang Y
Year: 2009
Journal: J Immunol
Title: Gamma-aminobutyric acid transporter 1 negatively regulates T cell activation and survival through protein kinase C-dependent signaling pathways.
Volume: 183
Issue: 5
Pages: 3488-95
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Publication
22158479 | J:202211
 
First Author: Nguyen D
Year: 2011
Journal: Cell Death Dis
Title: A new vicious cycle involving glutamate excitotoxicity, oxidative stress and mitochondrial dynamics.
Volume: 2
Pages: e240
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Publication
37835445 | J:358255
 
First Author: Zhu Y
Year: 2023
Journal: Cancers (Basel)
Title: The Tetraspanin Tspan8 Associates with Endothelin Converting Enzyme ECE1 and Regulates Its Activity.
Volume: 15
Issue: 19
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Publication
21737674 | J:183038
First Author: Cai W
Year: 2011
Journal: Mol Biol Cell
Title: An evolutionarily conserved Rit GTPase-p38 MAPK signaling pathway mediates oxidative stress resistance.
Volume: 22
Issue: 17
Pages: 3231-41
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Publication
34023385 | J:306284
First Author: Larson-Casey JL
Year: 2021
Journal: J Biol Chem
Title: NOX4 regulates macrophage apoptosis resistance to induce fibrotic progression.
Volume: 297
Issue: 1
Pages: 100810
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Publication
19148185 | J:164196
First Author: Finegan KG
Year: 2009
Journal: Cell Death Differ
Title: Regulation of neuronal survival by the extracellular signal-regulated protein kinase 5.
Volume: 16
Issue: 5
Pages: 674-83
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Publication
34325016 | J:321688
 
First Author: Rohrbach A
Year: 2021
Journal: Mol Metab
Title: Ablation of glucokinase-expressing tanycytes impacts energy balance and increases adiposity in mice.
Volume: 53
Pages: 101311
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Publication
25230579 | J:219237
First Author: Doberstein K
Year: 2015
Journal: Int J Cancer
Title: Antibody therapy to human L1CAM in a transgenic mouse model blocks local tumor growth but induces EMT.
Volume: 136
Issue: 5
Pages: E326-39
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Publication
20056832 | J:326639
First Author: Alejandro EU
Year: 2010
Journal: Endocrinology
Title: Acute insulin signaling in pancreatic beta-cells is mediated by multiple Raf-1 dependent pathways.
Volume: 151
Issue: 2
Pages: 502-12
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Publication
22197644 | J:274780
First Author: Kim YS
Year: 2012
Journal: Epilepsy Res
Title: Clusterin interaction with Bcl-xL is associated with seizure-induced neuronal death.
Volume: 99
Issue: 3
Pages: 240-51
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Publication
11195467 | J:67462
First Author: Yao R
Year: 2000
Journal: Exp Lung Res
Title: Inhibition of COX-2 and induction of apoptosis: two determinants of nonsteroidal anti-inflammatory drugs' chemopreventive efficacies in mouse lung tumorigenesis.
Volume: 26
Issue: 8
Pages: 731-42
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Publication
11839824 | J:74606
First Author: Wolfman JC
Year: 2002
Journal: Mol Cell Biol
Title: Cellular N-Ras promotes cell survival by downregulation of Jun N-terminal protein kinase and p38.
Volume: 22
Issue: 5
Pages: 1589-606
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Publication
9707599 | J:49404
First Author: Geng L
Year: 1998
Journal: Proc Natl Acad Sci U S A
Title: Widespread expression of an autoantigen-GAD65 transgene does not tolerize non-obese diabetic mice and can exacerbate disease.
Volume: 95
Issue: 17
Pages: 10055-60
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Publication
10079263 | J:53352
First Author: Brass DM
Year: 1999
Journal: Am J Pathol
Title: Reduced tumor necrosis factor-alpha and transforming growth factor-beta1 expression in the lungs of inbred mice that fail to develop fibroproliferative lesions consequent to asbestos exposure.
Volume: 154
Issue: 3
Pages: 853-62
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Publication
12095980 | J:78826
First Author: Tran NL
Year: 2002
Journal: J Biol Chem
Title: Signal transduction from N-cadherin increases Bcl-2. Regulation of the phosphatidylinositol 3-kinase/Akt pathway by homophilic adhesion and actin cytoskeletal organization.
Volume: 277
Issue: 36
Pages: 32905-14
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Publication
15226449 | J:91436
First Author: Jiang Q
Year: 2004
Journal: Mol Cell Biol
Title: Distinct regions of the interleukin-7 receptor regulate different Bcl2 family members.
Volume: 24
Issue: 14
Pages: 6501-13
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Publication
15153522 | J:90519
First Author: Chang I
Year: 2004
Journal: J Immunol
Title: Role of calcium in pancreatic islet cell death by IFN-gamma/TNF-alpha.
Volume: 172
Issue: 11
Pages: 7008-14
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Publication
15894568 | J:104780
First Author: Malhotra A
Year: 2005
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