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Search results 401 to 500 out of 565 for Bid

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Type Details Score
Publication
First Author: Du A
Year: 2009
Journal: Diabetes
Title: Islet-1 is required for the maturation, proliferation, and survival of the endocrine pancreas.
Volume: 58
Issue: 9
Pages: 2059-69
Publication  
First Author: Wang F
Year: 2017
Journal: Nat Commun
Title: Protein kinase C-alpha suppresses autophagy and induces neural tube defects via miR-129-2 in diabetic pregnancy.
Volume: 8
Pages: 15182
Publication
First Author: Breitwieser W
Year: 2007
Journal: Genes Dev
Title: Feedback regulation of p38 activity via ATF2 is essential for survival of embryonic liver cells.
Volume: 21
Issue: 16
Pages: 2069-82
Publication
First Author: Soma S
Year: 2024
Journal: Stem Cells
Title: O-Linked N-Acetylglucosamine Transferase Ensures Survival of Mouse Fetal Liver Hematopoietic Progenitors Partly by Regulating Bcl-xL and Oxidative Phosphorylation.
Volume: 42
Issue: 1
Pages: 55-63
Publication  
First Author: Jones MR
Year: 2018
Journal: Front Genet
Title: A Comprehensive Analysis of Fibroblast Growth Factor Receptor 2b Signaling on Epithelial Tip Progenitor Cells During Early Mouse Lung Branching Morphogenesis.
Volume: 9
Pages: 746
Publication
First Author: Wu B
Year: 2023
Journal: J Am Heart Assoc
Title: Crk and Crkl Are Required in the Endocardial Lineage for Heart Valve Development.
Volume: 12
Issue: 18
Pages: e029683
Publication      
First Author: Freeman TC
Year: 1998
Journal: MGI Direct Data Submission
Title: Expression Mapping of Mouse Genes
Publication
First Author: Pagliarini DJ
Year: 2008
Journal: Cell
Title: A mitochondrial protein compendium elucidates complex I disease biology.
Volume: 134
Issue: 1
Pages: 112-23
Publication      
First Author: The Jackson Laboratory Backcross DNA Panel Mapping Resource
Year: 1999
Journal: Database Release
Title: JAX BSS Panel Mapping Data
Publication
First Author: Ko MS
Year: 2000
Journal: Development
Title: Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development.
Volume: 127
Issue: 8
Pages: 1737-49
Publication
First Author: Hansen J
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome.
Volume: 100
Issue: 17
Pages: 9918-22
Publication
First Author: Friedel RH
Year: 2007
Journal: Brief Funct Genomic Proteomic
Title: EUCOMM--the European conditional mouse mutagenesis program.
Volume: 6
Issue: 3
Pages: 180-5
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations for FANTOM2 data
Publication  
First Author: Bedogni F
Year: 2021
Journal: Front Mol Neurosci
Title: Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development.
Volume: 14
Pages: 686034
Publication      
First Author: Lennon G
Year: 1999
Journal: Database Download
Title: WashU-HHMI Mouse EST Project
Publication      
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
Publication
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
Publication        
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
Publication
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
Publication        
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
Publication
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
Publication      
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
Publication        
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Publication        
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Publication      
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication        
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication      
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication
First Author: Cao Q
Year: 2004
Journal: J Immunol
Title: The E2F-1 transcription factor promotes caspase-8 and bid expression, and enhances Fas signaling in T cells.
Volume: 173
Issue: 2
Pages: 1111-7
Publication
First Author: Tan KO
Year: 1999
Journal: J Biol Chem
Title: A novel BH3-like domain in BID is required for intramolecular interaction and autoinhibition of pro-apoptotic activity.
Volume: 274
Issue: 34
Pages: 23687-90
Publication
First Author: Casciola-Rosen L
Year: 2007
Journal: J Biol Chem
Title: Mouse and human granzyme B have distinct tetrapeptide specificities and abilities to recruit the bid pathway.
Volume: 282
Issue: 7
Pages: 4545-52
Publication
First Author: Kook S
Year: 2014
Journal: Cell Death Differ
Title: Caspase-cleaved arrestin-2 and BID cooperatively facilitate cytochrome C release and cell death.
Volume: 21
Issue: 1
Pages: 172-84
Publication
First Author: Viswanath V
Year: 2001
Journal: J Neurosci
Title: Caspase-9 activation results in downstream caspase-8 activation and bid cleavage in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced Parkinson's disease.
Volume: 21
Issue: 24
Pages: 9519-28
Interaction Experiment
Description: A stapled BID BH3 helix directly binds and activates BAX.
Interaction Experiment
Description: A role for proapoptotic BID in the DNA-damage response.
Interaction Experiment
Description: Proapoptotic BID is an ATM effector in the DNA-damage response.
Pathway
Publication  
First Author: Kuriyama S
Year: 2018
Journal: Cell Death Discov
Title: PLEKHN1 promotes apoptosis by enhancing Bax-Bak hetro-oligomerization through interaction with Bid in human colon cancer.
Volume: 4
Pages: 11
GO Term
GO Term
Publication
First Author: Hsu SH
Year: 2013
Journal: Am J Pathol
Title: Hepatic loss of miR-122 predisposes mice to hepatobiliary cyst and hepatocellular carcinoma upon diethylnitrosamine exposure.
Volume: 183
Issue: 6
Pages: 1719-30
Publication
First Author: Wang B
Year: 2014
Journal: Hepatology
Title: Reciprocal regulation of microRNA-122 and c-Myc in hepatocellular cancer: role of E2F1 and transcription factor dimerization partner 2.
Volume: 59
Issue: 2
Pages: 555-66
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein
Organism: Mus musculus/domesticus
Length: 247  
Fragment?: false
Interaction Experiment
Description: Bid Promotes K63-Linked Polyubiquitination of Tumor Necrosis Factor Receptor Associated Factor 6 (TRAF6) and Sensitizes to Mutant SOD1-Induced Proinflammatory Signaling in Microglia.
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein
Organism: Mus musculus/domesticus
Length: 496  
Fragment?: false
Protein Domain
Type: Family
Description: Pleckstrin homology domain-containing family N member 1 (PLEKHN1), also known as CLPABP, is a cardiolipin phosphatidic acid binding protein that associates with microtubules and accumulates in RNAgranules, which contain cytochrome-c mRNA []. It binds to Bid (a pro-apoptotic protein), removes Bid from transient Bid-Bax complexes, and promotes apoptosis [].
Allele
Name: BH3 interacting domain death agonist; targeted mutation 1, Andreas Strasser
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
Strain
Attribute String: coisogenic, mutant strain, targeted mutation
Allele
Name: BH3 interacting domain death agonist; targeted mutation 1.1, Andreas Strasser
Allele Type: Targeted
Attribute String: Null/knockout
Genotype
Symbol: Bid/Bid
Background: involves: BALB/cJ * C57BL/6 * NZB
Zygosity: hm
Has Mutant Allele: true
Publication
First Author: Roy CR
Year: 2009
Journal: Sci Signal
Title: Bacterial FIC Proteins AMP Up Infection.
Volume: 2
Issue: 62
Pages: pe14
Publication
First Author: Goepfert A
Year: 2013
Journal: PLoS One
Title: Conserved inhibitory mechanism and competent ATP binding mode for adenylyltransferases with Fic fold.
Volume: 8
Issue: 5
Pages: e64901
Publication
First Author: Sano E
Year: 2008
Journal: Biochim Biophys Acta
Title: Novel tyrosine phosphorylated and cardiolipin-binding protein CLPABP functions as mitochondrial RNA granule.
Volume: 1783
Issue: 6
Pages: 1036-47
Protein Domain
Type: Domain
Description: VbhT is a bacterial Fic protein of the mammalian pathogen B. schoenbuchensis. It is composed of an N-terminal FIC domain and a C-terminal BID domain. FIC domains are known to catalyse adenylylation (also called AMPylation). This entry represents VbhA, an antitoxin that binds FIC domain (filamentation induced by cyclic AMP) of VbhT and inhibits its activity. It inhibits the adenylylation activity of VbhT by positioning close to the putative ATP-binding site, hence competing with ATP binding [].
Protein Domain
Type: Domain
Description: VbhA is the antitoxin to VbhT. VbhT is a toxin of the mammalian pathogen Bartonella schoenbuchensis responsible for the disruptive adenylation of host proteins []. VbhT is composed of an N-terminal FIC domain and a C-terminal BID domain. VbhT also induces FIC-domain-mediated growth arrest in bacteria. It is inhibited by this antitoxin which binds to block the ATP binding site of the VbhT FIC domain []. The antitoxin is related to an N-terminal domain in several Fic family proteins [].
Protein Domain
Type: Homologous_superfamily
Description: VbhT is a bacterial Fic protein of the mammalian pathogen B. schoenbuchensis. It is composed of an N-terminal FIC domain and a C-terminal BID domain. FIC domains are known to catalyse adenylylation (also called AMPylation). This entry represents VbhA, an antitoxin that binds FIC domain (filamentation induced by cyclic AMP) of VbhT and inhibits its activity. It inhibits the adenylylation activity of VbhT by positioning close to the putative ATP-binding site, hence competing with ATP binding [].Structurally, VbhA consists of 3 alpha helices.
Protein Domain
Type: Domain
Description: PLEKHN1 (also known as CLPABP) is a cardiolipin phosphatidic acid binding protein that associates with microtubules and accumulates in RNA granules, which contain cytochrome-c mRNA []. It binds to Bid (a pro-apoptotic protein), removes Bid from transient Bid-Bax complexes, and promotes apoptosis []. This entry represents the PH domain of PLEKHN1. PH domains have diverse functions, but in general are involved in targeting proteins to the appropriate cellular location or in the interaction with a binding partner []. They share little sequence conservation, but all have a commonfold, which is electrostatically polarized. Less than 10% of PH domains bind phosphoinositide phosphates (PIPs) with high affinity and specificity []. PH domains are distinguished from other PIP-binding domains by their specific high-affinity binding to PIPs with two vicinal phosphate groups: PtdIns(3,4)P2, PtdIns(4,5)P2 or PtdIns(3,4,5)P3 which results in targeting some PH domain proteins to the plasma membrane []. A few display strong specificity in lipid binding. Any specificity is usually determined by loop regions or insertions in the N terminus of the domain, which are not conserved across all PH domains. PH domains are found in cellular signaling proteins such as serine/threonine kinase, tyrosine kinases, regulators of G-proteins, endocytotic GTPases, adaptors, as well as cytoskeletal associated molecules and in lipid associated enzymes [].
HT Experiment
Series Id: GSE54418
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
Publication
First Author: Engel P
Year: 2012
Journal: Nature
Title: Adenylylation control by intra- or intermolecular active-site obstruction in Fic proteins.
Volume: 482
Issue: 7383
Pages: 107-10
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein
Organism: Mus musculus/domesticus
Length: 480  
Fragment?: false
Publication
First Author: Papadakis ES
Year: 2006
Journal: FEBS Lett
Title: The regulation of Bax by c-Jun N-terminal protein kinase (JNK) is a prerequisite to the mitochondrial-induced apoptotic pathway.
Volume: 580
Issue: 5
Pages: 1320-6
Publication
First Author: Vander Heiden MG
Year: 2001
Journal: J Biol Chem
Title: Bcl-xL promotes the open configuration of the voltage-dependent anion channel and metabolite passage through the outer mitochondrial membrane.
Volume: 276
Issue: 22
Pages: 19414-9
Publication
First Author: Malia TJ
Year: 2007
Journal: Biochemistry
Title: NMR structural investigation of the mitochondrial outer membrane protein VDAC and its interaction with antiapoptotic Bcl-xL.
Volume: 46
Issue: 2
Pages: 514-25
Protein Domain
Type: Family
Description: VDAC-1 (outer mitochondrial membrane protein porin 1) is a voltage dependent anion channel that mediates the flow of metabolites and ions across the outer mitochondrial membrane. VDAC-1 appeares to be a pro-apoptotic protein through oligomerisation []. It is implicated in cell death induction for its ability to interact with BAX, a protein belonging to the BCL-2 protein family. BAX plays a role in apoptosis and mitochondrial function regulation via multiple protein-protein interactions with BCL-2, BAK, BID or other members of the family [, ]. Voltage dependent anion channels (VDACs) or porins by analogy with bacterial porins, are pore-forming proteins associated with mitochondria, although they are also present in the endoplasmic reticulum (ER) []and plasma membrane []. In mammals, three VDAC isoforms have been identified: VDAC1 to 3. They have a very similar predicted structure, consisting of a 19 amphipathic β-strands barrel with an N-terminal α-helix in the central pore [, ]. The channel opening faces both the cytosol and mitochondrial intermembrane space [, ]. They play a major role in cellular energetic metabolism due to its ability to allow the exchange of molecules between the cytosol and the mitochondrial intermembrane space. They may also play a role in cell death. However, several mouse gene knock out studies show that VDACs are dispensable for both MPT (mitochondrial permeability transition) and Bcl-2 family member-driven cell death [, ].
Publication
First Author: Lindemann RK
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: Analysis of the apoptotic and therapeutic activities of histone deacetylase inhibitors by using a mouse model of B cell lymphoma.
Volume: 104
Issue: 19
Pages: 8071-6
Publication
First Author: Mérino D
Year: 2009
Journal: J Cell Biol
Title: The role of BH3-only protein Bim extends beyond inhibiting Bcl-2-like prosurvival proteins.
Volume: 186
Issue: 3
Pages: 355-62
Publication
First Author: Zheng JH
Year: 2018
Journal: Cell Rep
Title: Intrinsic Instability of BOK Enables Membrane Permeabilization in Apoptosis.
Volume: 23
Issue: 7
Pages: 2083-2094.e6
Publication
First Author: Namba T
Year: 2013
Journal: Cell Rep
Title: CDIP1-BAP31 complex transduces apoptotic signals from endoplasmic reticulum to mitochondria under endoplasmic reticulum stress.
Volume: 5
Issue: 2
Pages: 331-9
Publication
First Author: Hockings C
Year: 2018
Journal: Cell Death Differ
Title: Mcl-1 and Bcl-xL sequestration of Bak confers differential resistance to BH3-only proteins.
Volume: 25
Issue: 4
Pages: 719-732
Publication
First Author: Tan CT
Year: 2016
Journal: Cell Rep
Title: MOAP-1 Mediates Fas-Induced Apoptosis in Liver by Facilitating tBid Recruitment to Mitochondria.
Volume: 16
Issue: 1
Pages: 174-185
Publication
First Author: Sim GK
Year: 1990
Journal: Cell
Title: Dominantly inherited expression of BID, an invariant undiversified T cell receptor delta chain.
Volume: 61
Issue: 3
Pages: 397-405
Publication
First Author: Luo X
Year: 1998
Journal: Cell
Title: Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors.
Volume: 94
Issue: 4
Pages: 481-90
Publication
First Author: Kaiserman D
Year: 2006
Journal: J Cell Biol
Title: The major human and mouse granzymes are structurally and functionally divergent.
Volume: 175
Issue: 4
Pages: 619-30
Publication
First Author: Lin CF
Year: 2007
Journal: J Cell Sci
Title: GSK-3beta acts downstream of PP2A and the PI 3-kinase-Akt pathway, and upstream of caspase-2 in ceramide-induced mitochondrial apoptosis.
Volume: 120
Issue: Pt 16
Pages: 2935-43
Publication
First Author: Ott M
Year: 2007
Journal: J Biol Chem
Title: The mitochondrial TOM complex is required for tBid/Bax-induced cytochrome c release.
Volume: 282
Issue: 38
Pages: 27633-9
Publication
First Author: Tobaben S
Year: 2011
Journal: Cell Death Differ
Title: Bid-mediated mitochondrial damage is a key mechanism in glutamate-induced oxidative stress and AIF-dependent cell death in immortalized HT-22 hippocampal neurons.
Volume: 18
Issue: 2
Pages: 282-92
Publication
First Author: Weaver D
Year: 2014
Journal: Mol Cell
Title: Distribution and apoptotic function of outer membrane proteins depend on mitochondrial fusion.
Volume: 54
Issue: 5
Pages: 870-8
Publication  
First Author: Alsop AE
Year: 2015
Journal: Nat Commun
Title: Dissociation of Bak α1 helix from the core and latch domains is required for apoptosis.
Volume: 6
Pages: 6841
Publication    
First Author: Lim CL
Year: 2020
Journal: Elife
Title: Estrogen exacerbates mammary involution through neutrophil-dependent and -independent mechanism.
Volume: 9
Protein
Organism: Mus musculus/domesticus
Length: 610  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 611  
Fragment?: false