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Search results 401 to 485 out of 485 for Casp4

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Type Details Score
Publication
25774715 | J:231714
First Author: Man SM
Year: 2015
Journal: Nat Immunol
Title: The transcription factor IRF1 and guanylate-binding proteins target activation of the AIM2 inflammasome by Francisella infection.
Volume: 16
Issue: 5
Pages: 467-75
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Publication
30021146 | J:289210
First Author: Mandal P
Year: 2018
Journal: Immunity
Title: Caspase-8 Collaborates with Caspase-11 to Drive Tissue Damage and Execution of Endotoxic Shock.
Volume: 49
Issue: 1
Pages: 42-55.e6
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Publication
22365665 | J:181625
First Author: Vince JE
Year: 2012
Journal: Immunity
Title: Inhibitor of apoptosis proteins limit RIP3 kinase-dependent interleukin-1 activation.
Volume: 36
Issue: 2
Pages: 215-27
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Publication
25693118 | J:221796
 
First Author: Lawlor KE
Year: 2015
Journal: Nat Commun
Title: RIPK3 promotes cell death and NLRP3 inflammasome activation in the absence of MLKL.
Volume: 6
Pages: 6282
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Publication
10618441 | J:59317
First Author: Roth KA
Year: 2000
Journal: Proc Natl Acad Sci U S A
Title: Epistatic and independent functions of caspase-3 and Bcl-X(L) in developmental programmed cell death.
Volume: 97
Issue: 1
Pages: 466-71
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Publication
10377054 | J:56116
First Author: Exley GE
Year: 1999
Journal: Biol Reprod
Title: Expression of caspase and BCL-2 apoptotic family members in mouse preimplantation embryos.
Volume: 61
Issue: 1
Pages: 231-9
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Publication
19801895 | J:155983
First Author: Ikeda T
Year: 2009
Journal: J Vet Med Sci
Title: Expression of caspase family and muscle- and apoptosis-specific genes during skeletal myogenesis in mouse embryo.
Volume: 71
Issue: 9
Pages: 1161-8
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Publication
27917412 | J:290369
 
First Author: Kuriakose T
Year: 2016
Journal: Sci Immunol
Title: ZBP1/DAI is an innate sensor of influenza virus triggering the NLRP3 inflammasome and programmed cell death pathways.
Volume: 1
Issue: 2
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Publication
27709293 | J:261957
First Author: Svandova EB
Year: 2017
Journal: Histochem Cell Biol
Title: Expression of Fas, FasL, caspase-8 and other factors of the extrinsic apoptotic pathway during the onset of interdigital tissue elimination.
Volume: 147
Issue: 4
Pages: 497-510
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Publication
35139355 | J:324833
First Author: Simpson DS
Year: 2022
Journal: Immunity
Title: Interferon-γ primes macrophages for pathogen ligand-induced killing via a caspase-8 and mitochondrial cell death pathway.
Volume: 55
Issue: 3
Pages: 423-441.e9
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Publication
29576451 | J:262477
First Author: Karki R
Year: 2018
Journal: Cell
Title: IRF8 Regulates Transcription of Naips for NLRC4 Inflammasome Activation.
Volume: 173
Issue: 4
Pages: 920-933.e13
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Publication
33278357 | J:361144
First Author: Karki R
Year: 2021
Journal: Cell
Title: Synergism of TNF-α and IFN-γ Triggers Inflammatory Cell Death, Tissue Damage, and Mortality in SARS-CoV-2 Infection and Cytokine Shock Syndromes.
Volume: 184
Issue: 1
Pages: 149-168.e17
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Publication
38409108 | J:361094
First Author: Han JH
Year: 2024
Journal: Nat Commun
Title: NINJ1 mediates inflammatory cell death, PANoptosis, and lethality during infection conditions and heat stress.
Volume: 15
Issue: 1
Pages: 1739
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Publication
28923684 | J:252121
First Author: McCoy AM
Year: 2017
Journal: Am J Pathol
Title: IKKβ Activation in the Fetal Lung Mesenchyme Alters Lung Vascular Development but Not Airway Morphogenesis.
Volume: 187
Issue: 12
Pages: 2635-2644
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Publication
27760760 | J:238745
First Author: Nishikii H
Year: 2016
Journal: Blood
Title: DR3 signaling modulates the function of Foxp3+ regulatory T cells and the severity of acute graft-versus-host disease.
Volume: 128
Issue: 24
Pages: 2846-2858
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Publication
27914912 | J:240319
First Author: Stauber M
Year: 2017
Journal: Dev Biol
Title: Identification of FOXJ1 effectors during ciliogenesis in the foetal respiratory epithelium and embryonic left-right organiser of the mouse.
Volume: 423
Issue: 2
Pages: 170-188
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Publication
37813816 | J:358134
First Author: Soma S
Year: 2024
Journal: Stem Cells
Title: O-Linked N-Acetylglucosamine Transferase Ensures Survival of Mouse Fetal Liver Hematopoietic Progenitors Partly by Regulating Bcl-xL and Oxidative Phosphorylation.
Volume: 42
Issue: 1
Pages: 55-63
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Publication
12819136 | J:84168
First Author: Reed JC
Year: 2003
Journal: Genome Res
Title: Comparative analysis of apoptosis and inflammation genes of mice and humans.
Volume: 13
Issue: 6B
Pages: 1376-88
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Publication
21386911 | J:171050
First Author: Thiagarajan RD
Year: 2011
Journal: PLoS One
Title: Identification of anchor genes during kidney development defines ontological relationships, molecular subcompartments and regulatory pathways.
Volume: 6
Issue: 2
Pages: e17286
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
27626380 | J:236599
First Author: Dickinson ME
Year: 2016
Journal: Nature
Title: High-throughput discovery of novel developmental phenotypes.
Volume: 537
Issue: 7621
Pages: 508-514
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Publication
24194600 | J:228563
First Author: Koscielny G
Year: 2014
Journal: Nucleic Acids Res
Title: The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data.
Volume: 42
Issue: Database issue
Pages: D802-9
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Publication
- | J:204739
     
First Author: International Knockout Mouse Consortium
Year: 2014
Journal: Database Download
Title: MGI download of modified allele data from IKMC and creation of new knockout alleles
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Publication
- | J:204812
     
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
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Publication
- | J:148605
     
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
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Publication
- | J:171409
     
First Author: GUDMAP Consortium
Year: 2004
Journal: www.gudmap.org
Title: GUDMAP: the GenitoUrinary Development Molecular Anatomy Project
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
- | J:155856
       
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
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Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
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Publication
- | J:72247
       
First Author: DDB, FB, MGI, GOA, ZFIN curators
Year: 2001
Title: Gene Ontology annotation through association of InterPro records with GO terms
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Publication
- | J:78475
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Allele
Casp4<em1Smoc> | MGI:7288650
Name: caspase 4, apoptosis-related cysteine peptidase; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Strain
MGI:6428305 | C57BL/6JSmoc-Casp4<em1Smoc>/Smoc
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
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Protein
Q8BM55
Organism: Mus musculus/domesticus
Length: 687  
Fragment?: false
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Protein
D3Z6S1
Organism: Mus musculus/domesticus
Length: 642  
Fragment?: false
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Publication
23661706 | -
First Author: Li C
Year: 2013
Journal: J Biol Chem
Title: Transmembrane Protein 214 (TMEM214) mediates endoplasmic reticulum stress-induced caspase 4 enzyme activation and apoptosis.
Volume: 288
Issue: 24
Pages: 17908-17
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Protein Domain
IPR019308 | TMEM214
Type: Family
Description: TMEM214 is a critical mediator, in cooperation with CASP4, of endoplasmic reticulum-stress induced apoptosis. It is required or the activation of CASP4 following endoplasmic reticulum stress [].
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Allele
Casp12<tm1Dwni> | MGI:3832547
Name: caspase 12; targeted mutation 1, Donald W Nicholson
Allele Type: Targeted
Attribute String: Null/knockout
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Publication
16625199 | J:144912
First Author: Saleh M
Year: 2006
Journal: Nature
Title: Enhanced bacterial clearance and sepsis resistance in caspase-12-deficient mice.
Volume: 440
Issue: 7087
Pages: 1064-8
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Publication
26207309 | J:230955
First Author: Bhootada Y
Year: 2015
Journal: Invest Ophthalmol Vis Sci
Title: Targeting Caspase-12 to Preserve Vision in Mice With Inherited Retinal Degeneration.
Volume: 56
Issue: 8
Pages: 4725-33
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Allele
Tg(CASP4)1Bux | MGI:7433250
Name: transgene insertion 1, Joseph Buxbaum
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
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Genotype
Genotype
Symbol: Casp12/Casp12
Background: involves: 129S1/SvImJ * C57BL/6
Zygosity: hm
Has Mutant Allele: true
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Publication
20818395 | J:164686
First Author: Wang P
Year: 2010
Journal: Nat Immunol
Title: Caspase-12 controls West Nile virus infection via the viral RNA receptor RIG-I.
Volume: 11
Issue: 10
Pages: 912-9
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Publication
20876354 | J:165191
First Author: Labbé K
Year: 2010
Journal: J Immunol
Title: Caspase-12 dampens the immune response to malaria independently of the inflammasome by targeting NF-kappaB signaling.
Volume: 185
Issue: 9
Pages: 5495-502
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Publication
19745106 | J:156421
First Author: Jenkins D
Year: 2010
Journal: Nephrol Dial Transplant
Title: Analysis of TSHZ2 and TSHZ3 genes in congenital pelvi-ureteric junction obstruction.
Volume: 25
Issue: 1
Pages: 54-60
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Publication
18776146 | J:138769
First Author: Caubit X
Year: 2008
Journal: Development
Title: Teashirt 3 is necessary for ureteral smooth muscle differentiation downstream of SHH and BMP4.
Volume: 135
Issue: 19
Pages: 3301-10
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Publication
20631175 | J:162557
First Author: Caubit X
Year: 2010
Journal: J Neurosci
Title: Teashirt 3 regulates development of neurons involved in both respiratory rhythm and airflow control.
Volume: 30
Issue: 28
Pages: 9465-76
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Protein Domain
IPR026810 | Tshz3
Type: Family
Description: Teashirt 3 is a transcriptional regulator involved in developmental processes []. It has function in association with APBB1, SET and HDAC factors as a transcriptional repressor, that inhibits the expression of CASP4. TSHZ3-mediated transcription repression involves the recruitment of histone deacetylases HDAC1 and HDAC2. It associates with chromatin in a region surrounding the CASP4 transcriptional start site(s). It regulates the development of neurons involved in both respiratory rhythm and airflow control []. It promotes maintenance of nucleus ambiguus (nA) motoneurons, which govern upper airway function, and establishes a respiratory rhythm generator (RRG) activity compatible with survival at birth. It is involved in the differentiation of the proximal uretic smooth muscle cells during developmental processes []. It is involved in the up-regulation of myocardin, that directs the expression of smooth muscle cells in the proximal ureter [].
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Publication
20226691 | J:158664
First Author: Dupaul-Chicoine J
Year: 2010
Journal: Immunity
Title: Control of intestinal homeostasis, colitis, and colitis-associated colorectal cancer by the inflammatory caspases.
Volume: 32
Issue: 3
Pages: 367-78
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Strain
MGI:7433251 | STOCK Casp4<del> Tg(CASP4)1Bux/J
Attribute String: mutant strain, transgenic, targeted mutation, variant allele
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Publication
29098296 | J:254668
First Author: Basova LV
Year: 2017
Journal: Invest Ophthalmol Vis Sci
Title: Manipulation of Panx1 Activity Increases the Engraftment of Transplanted Lacrimal Gland Epithelial Progenitor Cells.
Volume: 58
Issue: 13
Pages: 5654-5665
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Publication
14973285 | -
First Author: Manfroid I
Year: 2004
Journal: Development
Title: Three putative murine Teashirt orthologues specify trunk structures in Drosophila in the same way as the Drosophila teashirt gene.
Volume: 131
Issue: 5
Pages: 1065-73
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Publication
28082356 | J:240695
First Author: Diamanti MA
Year: 2017
Journal: J Exp Med
Title: IKKα controls ATG16L1 degradation to prevent ER stress during inflammation.
Volume: 214
Issue: 2
Pages: 423-437
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Protein
Q8CGV9
Organism: Mus musculus/domesticus
Length: 1081  
Fragment?: false
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Protein
Q8BI94
Organism: Mus musculus/domesticus
Length: 232  
Fragment?: false
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Protein
A0A0R4J017
Organism: Mus musculus/domesticus
Length: 1081  
Fragment?: false
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Protein
Q8BI40
Organism: Mus musculus/domesticus
Length: 523  
Fragment?: false
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Protein
Q8BY61
Organism: Mus musculus/domesticus
Length: 753  
Fragment?: true
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Protein
B2RWR9
Organism: Mus musculus/domesticus
Length: 1081  
Fragment?: false
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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