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Search results 401 to 500 out of 1059 for Casp8

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Type Details Score
Publication
23645208 | J:228626
First Author: Sagulenko V
Year: 2013
Journal: Cell Death Differ
Title: AIM2 and NLRP3 inflammasomes activate both apoptotic and pyroptotic death pathways via ASC.
Volume: 20
Issue: 9
Pages: 1149-60
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Publication
24799700 | J:211054
First Author: Philip NH
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Caspase-8 mediates caspase-1 processing and innate immune defense in response to bacterial blockade of NF-κB and MAPK signaling.
Volume: 111
Issue: 20
Pages: 7385-90
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Publication
28366204 | J:241350
First Author: Daniels BP
Year: 2017
Journal: Cell
Title: RIPK3 Restricts Viral Pathogenesis via Cell Death-Independent Neuroinflammation.
Volume: 169
Issue: 2
Pages: 301-313.e11
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Publication
33798093 | J:303329
 
First Author: Müller K
Year: 2021
Journal: Proc Natl Acad Sci U S A
Title: JNK signaling prevents biliary cyst formation through a CASPASE-8-dependent function of RIPK1 during aging.
Volume: 118
Issue: 12
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Publication
28017612 | J:238416
First Author: Schneider AT
Year: 2017
Journal: Cancer Cell
Title: RIPK1 Suppresses a TRAF2-Dependent Pathway to Liver Cancer.
Volume: 31
Issue: 1
Pages: 94-109
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Publication
21382479 | J:171939
First Author: Zhang M
Year: 2011
Journal: Free Radic Biol Med
Title: Caveolin-1 mediates Fas-BID signaling in hyperoxia-induced apoptosis.
Volume: 50
Issue: 10
Pages: 1252-62
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Publication
25567679 | J:276762
First Author: Moriwaki K
Year: 2015
Journal: J Immunol
Title: A RIPK3-caspase 8 complex mediates atypical pro-IL-1β processing.
Volume: 194
Issue: 4
Pages: 1938-44
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Publication
31352002 | J:291197
First Author: Günther C
Year: 2019
Journal: Gastroenterology
Title: Interferon Lambda Promotes Paneth Cell Death Via STAT1 Signaling in Mice and Is Increased in Inflamed Ileal Tissues of Patients With Crohn's Disease.
Volume: 157
Issue: 5
Pages: 1310-1322.e13
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Publication
31276534 | J:278323
First Author: Beauchamp MC
Year: 2019
Journal: PLoS One
Title: Loss of function mutation of Eftud2, the gene responsible for mandibulofacial dysostosis with microcephaly (MFDM), leads to pre-implantation arrest in mouse.
Volume: 14
Issue: 7
Pages: e0219280
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Publication
28428949 | J:273663
 
First Author: Greve AS
Year: 2017
Journal: Front Cell Infect Microbiol
Title: P2X1, P2X4, and P2X7 Receptor Knock Out Mice Expose Differential Outcome of Sepsis Induced by α-Haemolysin Producing Escherichia coli.
Volume: 7
Pages: 113
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Publication
22819539 | J:187890
First Author: Rathinam VA
Year: 2012
Journal: Cell
Title: TRIF licenses caspase-11-dependent NLRP3 inflammasome activation by gram-negative bacteria.
Volume: 150
Issue: 3
Pages: 606-19
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Publication
24808358 | J:256714
First Author: Cuda CM
Year: 2014
Journal: J Immunol
Title: Caspase-8 acts as a molecular rheostat to limit RIPK1- and MyD88-mediated dendritic cell activation.
Volume: 192
Issue: 12
Pages: 5548-60
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Publication
35859177 | J:331943
First Author: Hubbard NW
Year: 2022
Journal: Nature
Title: ADAR1 mutation causes ZBP1-dependent immunopathology.
Volume: 607
Issue: 7920
Pages: 769-775
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Publication
10578172 | J:59875
First Author: Zheng TS
Year: 1999
Journal: Cell Death Differ
Title: Caspase knockouts: matters of life and death.
Volume: 6
Issue: 11
Pages: 1043-53
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Publication
12614028 | J:129916
First Author: Cha S
Year: 2002
Journal: Adv Exp Med Biol
Title: IDD3 and IDD5 alleles from nod mice mediate Sjögren's syndrome-like autoimmunity.
Volume: 506
Issue: Pt B
Pages: 1035-9
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Publication
25686493 | J:220480
First Author: Boaru SG
Year: 2015
Journal: Biochem Biophys Res Commun
Title: NLRP3 inflammasome expression is driven by NF-κB in cultured hepatocytes.
Volume: 458
Issue: 3
Pages: 700-6
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Publication
24144979 | J:206755
First Author: Zaman MM
Year: 2013
Journal: Mol Cell Biol
Title: Ubiquitination-deubiquitination by the TRIM27-USP7 complex regulates tumor necrosis factor alpha-induced apoptosis.
Volume: 33
Issue: 24
Pages: 4971-84
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Publication
30209212 | J:266342
First Author: Garcia-Carbonell R
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: Elevated A20 promotes TNF-induced and RIPK1-dependent intestinal epithelial cell death.
Volume: 115
Issue: 39
Pages: E9192-E9200
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Publication
29053143 | J:341430
First Author: Kalkavan H
Year: 2018
Journal: Cell Death Differ
Title: MOMP, cell suicide as a BCL-2 family business.
Volume: 25
Issue: 1
Pages: 46-55
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Publication
11739563 | J:73386
First Author: Viswanath V
Year: 2001
Journal: J Neurosci
Title: Caspase-9 activation results in downstream caspase-8 activation and bid cleavage in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced Parkinson's disease.
Volume: 21
Issue: 24
Pages: 9519-28
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Publication
10671365 | J:61369
 
First Author: Wang J
Year: 2000
Journal: J Cell Sci
Title: Roles of caspases in apoptosis, development, and cytokine maturation revealed by homozygous gene deficiencies.
Volume: 113 ( Pt 5)
Pages: 753-7
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Publication
9988219 | J:52983
First Author: Vaux DL
Year: 1999
Journal: Cell
Title: Cell death in development.
Volume: 96
Issue: 2
Pages: 245-54
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10101687 | J:53049
First Author: Colussi PA
Year: 1999
Journal: Immunol Cell Biol
Title: Targeted disruption of caspase genes in mice: what they tell us about the functions of individual caspases in apoptosis.
Volume: 77
Issue: 1
Pages: 58-63
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Publication
14748698 | J:87389
First Author: Kelkar RL
Year: 2003
Journal: Reproduction
Title: Expression of Fas and Fas ligand protein and mRNA in mouse oocytes and embryos.
Volume: 126
Issue: 6
Pages: 791-9
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15355863 | J:94928
First Author: De Paepe ME
Year: 2004
Journal: Am J Physiol Lung Cell Mol Physiol
Title: Fas/FasL-mediated apoptosis in perinatal murine lungs.
Volume: 287
Issue: 4
Pages: L730-42
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Publication
12480175 | J:136417
First Author: Tomioka M
Year: 2002
Journal: Brain Res Mol Brain Res
Title: In vivo role of caspases in excitotoxic neuronal death: generation and analysis of transgenic mice expressing baculoviral caspase inhibitor, p35, in postnatal neurons.
Volume: 108
Issue: 1-2
Pages: 18-32
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Publication
22343714 | J:204631
First Author: Wilfling F
Year: 2012
Journal: Cell Death Differ
Title: BH3-only proteins are tail-anchored in the outer mitochondrial membrane and can initiate the activation of Bax.
Volume: 19
Issue: 8
Pages: 1328-36
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Publication
25024200 | J:212247
First Author: Chi W
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Caspase-8 promotes NLRP1/NLRP3 inflammasome activation and IL-1β production in acute glaucoma.
Volume: 111
Issue: 30
Pages: 11181-6
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Publication
27552481 | J:239457
 
First Author: Lessard-Beaudoin M
Year: 2016
Journal: Neurobiol Aging
Title: Organ-specific alteration in caspase expression and STK3 proteolysis during the aging process.
Volume: 47
Pages: 50-62
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Publication
29563882 | J:310325
 
First Author: Svandova E
Year: 2018
Journal: Front Physiol
Title: Activation of Pro-apoptotic Caspases in Non-apoptotic Cells During Odontogenesis and Related Osteogenesis.
Volume: 9
Pages: 174
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Publication
30381458 | J:267270
First Author: Sarhan J
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: Caspase-8 induces cleavage of gasdermin D to elicit pyroptosis during Yersinia infection.
Volume: 115
Issue: 46
Pages: E10888-E10897
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Publication
24019532 | J:204906
First Author: Kaiser WJ
Year: 2013
Journal: J Biol Chem
Title: Toll-like receptor 3-mediated necrosis via TRIF, RIP3, and MLKL.
Volume: 288
Issue: 43
Pages: 31268-79
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Publication
24813849 | J:214394
First Author: Rickard JA
Year: 2014
Journal: Cell
Title: RIPK1 regulates RIPK3-MLKL-driven systemic inflammation and emergency hematopoiesis.
Volume: 157
Issue: 5
Pages: 1175-88
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Publication
11526440 | J:74158
First Author: Kuechle MK
Year: 2001
Journal: Cell Death Differ
Title: Caspase-14, a keratinocyte specific caspase: mRNA splice variants and expression pattern in embryonic and adult mouse.
Volume: 8
Issue: 8
Pages: 868-70
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Publication
25301392 | J:219674
First Author: Zhao Y
Year: 2015
Journal: Diabetologia
Title: Autoreactive T cells induce necrosis and not BCL-2-regulated or death receptor-mediated apoptosis or RIPK3-dependent necroptosis of transplanted islets in a mouse model of type 1 diabetes.
Volume: 58
Issue: 1
Pages: 140-8
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Publication
24632563 | J:210320
 
First Author: Josefsson EC
Year: 2014
Journal: Nat Commun
Title: Platelet production proceeds independently of the intrinsic and extrinsic apoptosis pathways.
Volume: 5
Pages: 3455
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32268091 | J:310108
First Author: Donado CA
Year: 2020
Journal: Cell Rep
Title: A Two-Cell Model for IL-1β Release Mediated by Death-Receptor Signaling.
Volume: 31
Issue: 1
Pages: 107466
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23509366 | J:195291
First Author: Uchiyama R
Year: 2013
Journal: J Immunol
Title: Fas-mediated inflammatory response in Listeria monocytogenes infection.
Volume: 190
Issue: 8
Pages: 4245-54
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Publication
31719149 | J:286548
First Author: Dasari TK
Year: 2020
Journal: J Biol Chem
Title: The nonreceptor tyrosine kinase SYK drives caspase-8/NLRP3 inflammasome-mediated autoinflammatory osteomyelitis.
Volume: 295
Issue: 11
Pages: 3394-3400
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Publication
30254289 | J:267737
First Author: Taraborrelli L
Year: 2018
Journal: Nat Commun
Title: LUBAC prevents lethal dermatitis by inhibiting cell death induced by TNF, TRAIL and CD95L.
Volume: 9
Issue: 1
Pages: 3910
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Publication
19119023 | J:143730
First Author: Kaufmann T
Year: 2009
Journal: Immunity
Title: Fatal hepatitis mediated by tumor necrosis factor TNFalpha requires caspase-8 and involves the BH3-only proteins Bid and Bim.
Volume: 30
Issue: 1
Pages: 56-66
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Publication
25474208 | J:246605
First Author: Zwolanek F
Year: 2014
Journal: PLoS Pathog
Title: The non-receptor tyrosine kinase Tec controls assembly and activity of the noncanonical caspase-8 inflammasome.
Volume: 10
Issue: 12
Pages: e1004525
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Publication
26998763 | J:258997
First Author: Martin BN
Year: 2016
Journal: Nat Immunol
Title: T cell-intrinsic ASC critically promotes T(H)17-mediated experimental autoimmune encephalomyelitis.
Volume: 17
Issue: 5
Pages: 583-92
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Publication
30485805 | J:271647
First Author: Chauhan D
Year: 2018
Journal: Cell Rep
Title: BAX/BAK-Induced Apoptosis Results in Caspase-8-Dependent IL-1β Maturation in Macrophages.
Volume: 25
Issue: 9
Pages: 2354-2368.e5
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Publication
19720838 | J:153779
First Author: Kovalenko A
Year: 2009
Journal: J Exp Med
Title: Caspase-8 deficiency in epidermal keratinocytes triggers an inflammatory skin disease.
Volume: 206
Issue: 10
Pages: 2161-77
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Publication
27396959 | J:259909
First Author: Najjar M
Year: 2016
Journal: Immunity
Title: RIPK1 and RIPK3 Kinases Promote Cell-Death-Independent Inflammation by Toll-like Receptor 4.
Volume: 45
Issue: 1
Pages: 46-59
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Publication
38548850 | J:348283
First Author: Solon M
Year: 2024
Journal: Cell Death Differ
Title: ZBP1 and TRIF trigger lethal necroptosis in mice lacking caspase-8 and TNFR1.
Volume: 31
Issue: 5
Pages: 672-682
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Publication
26269257 | J:224993
 
First Author: Wan CK
Year: 2015
Journal: Nat Commun
Title: IL-21-mediated non-canonical pathway for IL-1β production in conventional dendritic cells.
Volume: 6
Pages: 7988
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32561755 | J:292274
First Author: Hildebrand JM
Year: 2020
Journal: Nat Commun
Title: A missense mutation in the MLKL brace region promotes lethal neonatal inflammation and hematopoietic dysfunction.
Volume: 11
Issue: 1
Pages: 3150
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Publication
32234476 | J:288291
First Author: Muri J
Year: 2020
Journal: Cell Rep
Title: Cyclopentenone Prostaglandins and Structurally Related Oxidized Lipid Species Instigate and Share Distinct Pro- and Anti-inflammatory Pathways.
Volume: 30
Issue: 13
Pages: 4399-4417.e7
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31869420 | J:289534
 
First Author: Malireddi RKS
Year: 2020
Journal: J Exp Med
Title: Innate immune priming in the absence of TAK1 drives RIPK1 kinase activity-independent pyroptosis, apoptosis, necroptosis, and inflammatory disease.
Volume: 217
Issue: 3
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31243089 | J:279684
First Author: Sanjo H
Year: 2019
Journal: J Immunol
Title: Cutting Edge: TAK1 Safeguards Macrophages against Proinflammatory Cell Death.
Volume: 203
Issue: 4
Pages: 783-788
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32726624 | J:323547
First Author: de Vasconcelos NM
Year: 2020
Journal: Cell Rep
Title: An Apoptotic Caspase Network Safeguards Cell Death Induction in Pyroptotic Macrophages.
Volume: 32
Issue: 4
Pages: 107959
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24990442 | J:217122
First Author: Allam R
Year: 2014
Journal: EMBO Rep
Title: Mitochondrial apoptosis is dispensable for NLRP3 inflammasome activation but non-apoptotic caspase-8 is required for inflammasome priming.
Volume: 15
Issue: 9
Pages: 982-90
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Publication
26104484 | J:223015
 
First Author: Kang S
Year: 2015
Journal: Nat Commun
Title: Caspase-8 scaffolding function and MLKL regulate NLRP3 inflammasome activation downstream of TLR3.
Volume: 6
Pages: 7515
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22688338 | J:208533
First Author: Li X
Year: 2012
Journal: Diabetes
Title: Oxidative stress-induced JNK1/2 activation triggers proapoptotic signaling and apoptosis that leads to diabetic embryopathy.
Volume: 61
Issue: 8
Pages: 2084-92
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37329888 | J:338216
First Author: Vucur M
Year: 2023
Journal: Immunity
Title: Sublethal necroptosis signaling promotes inflammation and liver cancer.
Volume: 56
Issue: 7
Pages: 1578-1595.e8
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17108969 | J:118157
First Author: Smart N
Year: 2007
Journal: Nature
Title: Thymosin beta4 induces adult epicardial progenitor mobilization and neovascularization.
Volume: 445
Issue: 7124
Pages: 177-82
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31659279 | J:297034
First Author: Someda M
Year: 2020
Journal: Cell Death Differ
Title: Caspase-8, receptor-interacting protein kinase 1 (RIPK1), and RIPK3 regulate retinoic acid-induced cell differentiation and necroptosis.
Volume: 27
Issue: 5
Pages: 1539-1553
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28482072 | J:321352
First Author: Chen X
Year: 2017
Journal: Toxicol Sci
Title: Endoplasmic Reticulum Stress-Induced CHOP Inhibits PGC-1α and Causes Mitochondrial Dysfunction in Diabetic Embryopathy.
Volume: 158
Issue: 2
Pages: 275-285
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26649818 | J:228302
First Author: Wertz IE
Year: 2015
Journal: Nature
Title: Phosphorylation and linear ubiquitin direct A20 inhibition of inflammation.
Volume: 528
Issue: 7582
Pages: 370-5
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22037414 | J:180684
First Author: O'Donnell MA
Year: 2011
Journal: Nat Cell Biol
Title: Caspase 8 inhibits programmed necrosis by processing CYLD.
Volume: 13
Issue: 12
Pages: 1437-42
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18309324 | J:180458
First Author: Galluzzi L
Year: 2008
Journal: Cell Death Differ
Title: No death without life: vital functions of apoptotic effectors.
Volume: 15
Issue: 7
Pages: 1113-23
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10739653 | J:61549
First Author: Zheng TS
Year: 2000
Journal: Exp Cell Res
Title: Divinations and surprises: genetic analysis of caspase function in mice.
Volume: 256
Issue: 1
Pages: 67-73
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10087912 | J:52371
First Author: Kumar S
Year: 1999
Journal: Trends Biochem Sci
Title: Prodomains--adaptors--oligomerization: the pursuit of caspase activation in apoptosis.
Volume: 24
Issue: 1
Pages: 1-4
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10403638 | J:56171
First Author: Los M
Year: 1999
Journal: Immunity
Title: The role of caspases in development, immunity, and apoptotic signal transduction: lessons from knockout mice.
Volume: 10
Issue: 6
Pages: 629-39
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21746883 | J:175071
First Author: Irrinki KM
Year: 2011
Journal: Mol Cell Biol
Title: Requirement of FADD, NEMO, and BAX/BAK for aberrant mitochondrial function in tumor necrosis factor alpha-induced necrosis.
Volume: 31
Issue: 18
Pages: 3745-58
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21221781 | J:196570
First Author: Bae KB
Year: 2011
Journal: Transgenic Res
Title: Overexpression of Jazf1 induces cardiac malformation through the upregulation of pro-apoptotic genes in mice.
Volume: 20
Issue: 5
Pages: 1019-31
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23842495 | J:249198
First Author: Clavería C
Year: 2013
Journal: Nature
Title: Myc-driven endogenous cell competition in the early mammalian embryo.
Volume: 500
Issue: 7460
Pages: 39-44
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30420664 | J:268450
First Author: Lafont E
Year: 2018
Journal: Nat Cell Biol
Title: TBK1 and IKKε prevent TNF-induced cell death by RIPK1 phosphorylation.
Volume: 20
Issue: 12
Pages: 1389-1399
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10433968 | J:56924
First Author: Sagane K
Year: 1999
Journal: Gene
Title: Cloning and chromosomal mapping of mouse ADAM11, ADAM22 and ADAM23.
Volume: 236
Issue: 1
Pages: 79-86
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32298652 | J:290292
First Author: Zheng M
Year: 2020
Journal: Cell
Title: Caspase-6 Is a Key Regulator of Innate Immunity, Inflammasome Activation, and Host Defense.
Volume: 181
Issue: 3
Pages: 674-687.e13
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31358656 | J:279199
First Author: Ingram JP
Year: 2019
Journal: J Immunol
Title: ZBP1/DAI Drives RIPK3-Mediated Cell Death Induced by IFNs in the Absence of RIPK1.
Volume: 203
Issue: 5
Pages: 1348-1355
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20436477 | J:209127
First Author: Zaltsman Y
Year: 2010
Journal: Nat Cell Biol
Title: MTCH2/MIMP is a major facilitator of tBID recruitment to mitochondria.
Volume: 12
Issue: 6
Pages: 553-562
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24799678 | J:211055
First Author: Weng D
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Caspase-8 and RIP kinases regulate bacteria-induced innate immune responses and cell death.
Volume: 111
Issue: 20
Pages: 7391-6
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27071119 | J:232215
First Author: Gurung P
Year: 2016
Journal: Proc Natl Acad Sci U S A
Title: NLRP3 inflammasome plays a redundant role with caspase 8 to promote IL-1β-mediated osteomyelitis.
Volume: 113
Issue: 16
Pages: 4452-7
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29695863 | J:261640
First Author: Peltzer N
Year: 2018
Journal: Nature
Title: LUBAC is essential for embryogenesis by preventing cell death and enabling haematopoiesis.
Volume: 557
Issue: 7703
Pages: 112-117
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24832470 | J:230023
First Author: Viaud S
Year: 2015
Journal: Cell Death Differ
Title: Gut microbiome and anticancer immune response: really hot Sh*t!
Volume: 22
Issue: 2
Pages: 199-214
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26555174 | J:226752
First Author: Kondylis V
Year: 2015
Journal: Cancer Cell
Title: NEMO Prevents Steatohepatitis and Hepatocellular Carcinoma by Inhibiting RIPK1 Kinase Activity-Mediated Hepatocyte Apoptosis.
Volume: 28
Issue: 5
Pages: 582-598
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Publication
34625556 | J:312394
First Author: Hoste E
Year: 2021
Journal: Nat Commun
Title: OTULIN maintains skin homeostasis by controlling keratinocyte death and stem cell identity.
Volume: 12
Issue: 1
Pages: 5913
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29775594 | J:262835
First Author: Ke FFS
Year: 2018
Journal: Cell
Title: Embryogenesis and Adult Life in the Absence of Intrinsic Apoptosis Effectors BAX, BAK, and BOK.
Volume: 173
Issue: 5
Pages: 1217-1230.e17
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29786074 | J:275025
First Author: Sarhan J
Year: 2019
Journal: Cell Death Differ
Title: Constitutive interferon signaling maintains critical threshold of MLKL expression to license necroptosis.
Volume: 26
Issue: 2
Pages: 332-347
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25704009 | J:287726
First Author: Karki R
Year: 2015
Journal: Cell Host Microbe
Title: Concerted activation of the AIM2 and NLRP3 inflammasomes orchestrates host protection against Aspergillus infection.
Volume: 17
Issue: 3
Pages: 357-368
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34686350 | J:320929
First Author: Karki R
Year: 2021
Journal: Cell Rep
Title: ADAR1 restricts ZBP1-mediated immune response and PANoptosis to promote tumorigenesis.
Volume: 37
Issue: 3
Pages: 109858
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21791606 | J:175868
First Author: Takano J
Year: 2011
Journal: Mol Cell Biol
Title: Vital role of the calpain-calpastatin system for placental-integrity-dependent embryonic survival.
Volume: 31
Issue: 19
Pages: 4097-106
•
•
•
•
•
Publication
24489101 | J:209937
First Author: Shenderov K
Year: 2014
Journal: J Immunol
Title: Cutting edge: Endoplasmic reticulum stress licenses macrophages to produce mature IL-1β in response to TLR4 stimulation through a caspase-8- and TRIF-dependent pathway.
Volume: 192
Issue: 5
Pages: 2029-2033
•
•
•
•
•
Publication
30451870 | J:267513
First Author: Saavedra PHV
Year: 2018
Journal: Nat Commun
Title: Apoptosis of intestinal epithelial cells restricts Clostridium difficile infection in a model of pseudomembranous colitis.
Volume: 9
Issue: 1
Pages: 4846
•
•
•
•
•
Publication
32763970 | J:298138
First Author: Zheng M
Year: 2020
Journal: J Biol Chem
Title: Impaired NLRP3 inflammasome activation/pyroptosis leads to robust inflammatory cell death via caspase-8/RIPK3 during coronavirus infection.
Volume: 295
Issue: 41
Pages: 14040-14052
•
•
•
•
•
Publication
16183742 | J:101402
First Author: Berube C
Year: 2005
Journal: Proc Natl Acad Sci U S A
Title: Apoptosis caused by p53-induced protein with death domain (PIDD) depends on the death adapter protein RAIDD.
Volume: 102
Issue: 40
Pages: 14314-20
•
•
•
•
•
Publication
12404118 | J:103506
First Author: Sakamaki K
Year: 2002
Journal: Cell Death Differ
Title: Ex vivo whole-embryo culture of caspase-8-deficient embryos normalize their aberrant phenotypes in the developing neural tube and heart.
Volume: 9
Issue: 11
Pages: 1196-206
•
•
•
•
•
Publication
27130031 | J:315123
 
First Author: Zhong J
Year: 2016
Journal: Free Radic Biol Med
Title: Superoxide dismutase 2 overexpression alleviates maternal diabetes-induced neural tube defects, restores mitochondrial function and suppresses cellular stress in diabetic embryopathy.
Volume: 96
Pages: 234-44
•
•
•
•
•
Publication
10442092 | J:56649
First Author: Hofmann K
Year: 1999
Journal: Cell Mol Life Sci
Title: The modular nature of apoptotic signaling proteins.
Volume: 55
Issue: 8-9
Pages: 1113-28
•
•
•
•
•
Publication
28396396 | J:242134
First Author: Zhao Z
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: Formation of neurodegenerative aggresome and death-inducing signaling complex in maternal diabetes-induced neural tube defects.
Volume: 114
Issue: 17
Pages: 4489-4494
•
•
•
•
•
Publication
29891719 | J:263756
First Author: Amin P
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: Regulation of a distinct activated RIPK1 intermediate bridging complex I and complex II in TNFα-mediated apoptosis.
Volume: 115
Issue: 26
Pages: E5944-E5953
•
•
•
•
•
Publication
35417681 | J:334663
First Author: Iberg CA
Year: 2022
Journal: Cell Rep
Title: TNF-α sculpts a maturation process in vivo by pruning tolerogenic dendritic cells.
Volume: 39
Issue: 2
Pages: 110657
•
•
•
•
•
Publication
31848486 | J:306894
First Author: Jain A
Year: 2020
Journal: Nat Immunol
Title: T cells instruct myeloid cells to produce inflammasome-independent IL-1β and cause autoimmunity.
Volume: 21
Issue: 1
Pages: 65-74
•
•
•
•
•
Publication
24453255 | J:209447
First Author: Gurung P
Year: 2014
Journal: J Immunol
Title: FADD and caspase-8 mediate priming and activation of the canonical and noncanonical Nlrp3 inflammasomes.
Volume: 192
Issue: 4
Pages: 1835-46
•
•
•
•
•
Publication
31230859 | J:296482
First Author: Yamashita M
Year: 2019
Journal: Cell Stem Cell
Title: TNF-α Coordinates Hematopoietic Stem Cell Survival and Myeloid Regeneration.
Volume: 25
Issue: 3
Pages: 357-372.e7
•
•
•
•
•
Publication
30021146 | J:289210
First Author: Mandal P
Year: 2018
Journal: Immunity
Title: Caspase-8 Collaborates with Caspase-11 to Drive Tissue Damage and Execution of Endotoxic Shock.
Volume: 49
Issue: 1
Pages: 42-55.e6
•
•
•
•
•
Publication
31346084 | J:279163
First Author: Orvedahl A
Year: 2019
Journal: Proc Natl Acad Sci U S A
Title: Autophagy genes in myeloid cells counteract IFNγ-induced TNF-mediated cell death and fatal TNF-induced shock.
Volume: 116
Issue: 33
Pages: 16497-16506
•
•
•
•
•




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