Type |
Details |
Score |
Publication |
First Author: |
Footz TK |
Year: |
2001 |
Journal: |
Genome Res |
Title: |
Analysis of the cat eye syndrome critical region in humans and the region of conserved synteny in mice: a search for candidate genes at or near the human chromosome 22 pericentromere. |
Volume: |
11 |
Issue: |
6 |
Pages: |
1053-70 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
419
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chicken |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chicken |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
frog, western clawed |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
frog, African clawed |
|
•
•
•
•
•
|
Publication |
First Author: |
O'Brien SJ |
Year: |
1997 |
Journal: |
J Hered |
Title: |
Comparative gene mapping in the domestic cat (Felis catus). |
Volume: |
88 |
Issue: |
5 |
Pages: |
408-14 |
|
•
•
•
•
•
|
Publication |
First Author: |
Forooghian F |
Year: |
2000 |
Journal: |
J Mol Neurosci |
Title: |
Molecular analysis of trkC in the cat visual cortex. |
Volume: |
14 |
Issue: |
1-2 |
Pages: |
39-51 |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
This entry represents the human Cat eye syndrome critical region protein 6 (also known as transmembrane protein 121B) and its homologues [, ]. Cat Eye Syndrome (CES) is characterised clinically by the combination of coloboma of the iris and anal atresia with fistula. CES is a rare condition caused by the duplication of a 2 Mb region of human 22q11.2 resulting in four copies of the region rather than the usual two copies []. |
|
•
•
•
•
•
|
Author |
|
•
•
•
•
•
|
Author |
|
•
•
•
•
•
|
Publication |
First Author: |
van Tilbeurgh H |
Year: |
1997 |
Journal: |
EMBO J |
Title: |
Crystal structure of a new RNA-binding domain from the antiterminator protein SacY of Bacillus subtilis. |
Volume: |
16 |
Issue: |
16 |
Pages: |
5030-6 |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
CECR5 (cat eye syndrome critical region protein 5 also known as haloacid dehalogenase-like hydrolase domain-containing 5) gene is a candidate gene for the Cat Eye Syndrome (CES), a developmental disorder associated with the duplication of a 2 Mb region of 22q11.2 []. Its function isnot clear. |
|
•
•
•
•
•
|
Allele |
Name: |
cathepsin F; targeted mutation 1, Harold A Chapman |
Allele Type: |
Targeted |
Attribute String: |
Null/knockout |
|
•
•
•
•
•
|
Publication |
First Author: |
Dean M |
Year: |
1987 |
Journal: |
Genomics |
Title: |
Chromosomal localization of the met proto-oncogene in the mouse and cat genome. |
Volume: |
1 |
Issue: |
2 |
Pages: |
167-73 |
|
•
•
•
•
•
|
Publication |
First Author: |
Warren WC |
Year: |
1996 |
Journal: |
Gene |
Title: |
Cloning of the cDNAs coding for cat growth hormone and prolactin. |
Volume: |
168 |
Issue: |
2 |
Pages: |
247-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Dicipulo R |
Year: |
2021 |
Journal: |
Sci Rep |
Title: |
Cecr2 mutant mice as a model for human cat eye syndrome. |
Volume: |
11 |
Issue: |
1 |
Pages: |
3111 |
|
•
•
•
•
•
|
Publication |
First Author: |
Cho K |
Year: |
1998 |
Journal: |
Immunogenetics |
Title: |
Cloning and mapping of cat (Felis catus) immunoglobulin and T-cell receptor genes. |
Volume: |
47 |
Issue: |
3 |
Pages: |
226-33 |
|
•
•
•
•
•
|
Publication |
First Author: |
Weinberg RA |
Year: |
1997 |
Journal: |
Cell |
Title: |
The cat and mouse games that genes, viruses, and cells play. |
Volume: |
88 |
Issue: |
5 |
Pages: |
573-5 |
|
•
•
•
•
•
|
Publication |
First Author: |
Verrusio C |
Year: |
1964 |
Journal: |
Mouse News Lett |
Title: |
Shrivelled allele of Cat |
Volume: |
31 |
|
Pages: |
35 |
|
•
•
•
•
•
|
Publication |
First Author: |
Rupert JL |
Year: |
1988 |
Journal: |
Genet Res |
Title: |
The murine cataractogenic mutation, Cat Fraser, segregates independently of the gamma crystallin genes. |
Volume: |
51 |
Issue: |
1 |
Pages: |
23-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Shiels A |
Year: |
1993 |
Journal: |
Curr Eye Res |
Title: |
Aberrant expression of the gene for lens major intrinsic protein in the CAT mouse. |
Volume: |
12 |
Issue: |
10 |
Pages: |
913-21 |
|
•
•
•
•
•
|
Publication |
First Author: |
Murphy WJ |
Year: |
1999 |
Journal: |
Genome Res |
Title: |
Extensive conservation of sex chromosome organization between cat and human revealed by parallel radiation hybrid mapping. |
Volume: |
9 |
Issue: |
12 |
Pages: |
1223-30 |
|
•
•
•
•
•
|
Publication |
First Author: |
Dandeu JP |
Year: |
1992 |
Journal: |
Immunol Lett |
Title: |
H2 genotype and IgE immune response to Fel dI, the cat major allergen, in mice. |
Volume: |
33 |
Issue: |
3 |
Pages: |
229-32 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hosoki K |
Year: |
2016 |
Journal: |
J Allergy Clin Immunol |
Title: |
Myeloid differentiation protein 2 facilitates pollen- and cat dander-induced innate and allergic airway inflammation. |
Volume: |
137 |
Issue: |
5 |
Pages: |
1506-1513.e2 |
|
•
•
•
•
•
|
Publication |
First Author: |
Thomas R |
Year: |
1999 |
Journal: |
Cytogenet Cell Genet |
Title: |
Zoo-FISH analysis of dog chromosome 5: identification of conserved synteny with human and cat chromosomes. |
Volume: |
87 |
Issue: |
1-2 |
Pages: |
4-10 |
|
•
•
•
•
•
|
Publication |
First Author: |
Van der Gucht E |
Year: |
2003 |
Journal: |
Brain Res Mol Brain Res |
Title: |
Molecular cloning and differential expression of the cat immediate early gene c-fos. |
Volume: |
111 |
Issue: |
1-2 |
Pages: |
198-210 |
|
•
•
•
•
•
|
Publication |
First Author: |
Gebremedhin D |
Year: |
1999 |
Journal: |
Am J Physiol |
Title: |
Cannabinoid CB1 receptor of cat cerebral arterial muscle functions to inhibit L-type Ca2+ channel current. |
Volume: |
276 |
Issue: |
6 Pt 2 |
Pages: |
H2085-93 |
|
•
•
•
•
•
|
Publication |
First Author: |
Nguyen LQ |
Year: |
2002 |
Journal: |
Endocrinology |
Title: |
Cloning of the cat TSH receptor and evidence against an autoimmune etiology of feline hyperthyroidism. |
Volume: |
143 |
Issue: |
2 |
Pages: |
395-402 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hameister H |
Year: |
1997 |
Journal: |
Chromosome Res |
Title: |
Zoo-FISH analysis: the American mink (Mustela vison) closely resembles the cat karyotype. |
Volume: |
5 |
Issue: |
1 |
Pages: |
5-11 |
|
•
•
•
•
•
|
Publication |
First Author: |
Cho KW |
Year: |
1998 |
Journal: |
Mamm Genome |
Title: |
The cat immunoglobulin lambda light chain gene maps to chromosome D3p12-p11. |
Volume: |
9 |
Issue: |
2 |
Pages: |
178-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Suzuki M |
Year: |
2000 |
Journal: |
GenBank Submission |
Title: |
Mus musculus CAT mRNA for calcium transporting protein homolog, complete cds |
|
|
Pages: |
AB037373 |
|
•
•
•
•
•
|
UniProt Feature |
Begin: |
1 |
Description: |
Cat eye syndrome critical region protein 2 homolog |
Type: |
chain |
End: |
1453 |
|
•
•
•
•
•
|
Heritable Phenotypic Marker |
Type: |
heritable_phenotypic_marker |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Publication |
First Author: |
Karn RC |
Year: |
1994 |
Journal: |
Biochem Genet |
Title: |
The mouse salivary androgen-binding protein (ABP) alpha subunit closely resembles chain 1 of the cat allergen Fel dI. |
Volume: |
32 |
Issue: |
7-8 |
Pages: |
271-7 |
|
•
•
•
•
•
|
GO Term |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
357
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Allele |
Name: |
coiled-coil-helix-coiled-coil-helix domain containing 10; endonuclease-mediated mutation 8, Cat Lutz |
Allele Type: |
Endonuclease-mediated |
Attribute String: |
Humanized sequence |
|
•
•
•
•
•
|
Allele |
Name: |
transmembrane protein 106B; endonuclease-mediated mutation 1, Cat Lutz |
Allele Type: |
Endonuclease-mediated |
Attribute String: |
Null/knockout |
|
•
•
•
•
•
|
Publication |
First Author: |
Kalman K |
Year: |
2006 |
Journal: |
Biochim Biophys Acta |
Title: |
AQP0-LTR of the Cat Fr mouse alters water permeability and calcium regulation of wild type AQP0. |
Volume: |
1758 |
Issue: |
8 |
Pages: |
1094-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Cho KW |
Year: |
1997 |
Journal: |
Cytogenet Cell Genet |
Title: |
Assignment of the feline c-myc gene (MYC) to cat chromosome F2q21.2 by fluorescence in situ hybridization. |
Volume: |
78 |
Issue: |
2 |
Pages: |
135-6 |
|
•
•
•
•
•
|
Publication |
First Author: |
Qin H |
Year: |
1994 |
Journal: |
Biochem Biophys Res Commun |
Title: |
Isolation and structure of cat superfast myosin light chain-2 cDNA and evidence for the identity of its human homologue. |
Volume: |
200 |
Issue: |
3 |
Pages: |
1277-82 |
|
•
•
•
•
•
|
Publication |
First Author: |
Emara M |
Year: |
2011 |
Journal: |
J Biol Chem |
Title: |
Recognition of the major cat allergen Fel d 1 through the cysteine-rich domain of the mannose receptor determines its allergenicity. |
Volume: |
286 |
Issue: |
15 |
Pages: |
13033-40 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
234
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
1453
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Allele |
Name: |
cathepsin D; targeted mutation 1, Cristoph Peters |
Allele Type: |
Targeted |
Attribute String: |
Null/knockout |
|
•
•
•
•
•
|
Allele |
Name: |
cathepsin B; targeted mutation 1, Jan Deussing |
Allele Type: |
Targeted |
Attribute String: |
Null/knockout |
|
•
•
•
•
•
|
Publication |
First Author: |
Kunz S |
Year: |
2008 |
Journal: |
Am J Pathol |
Title: |
Lymphadenopathy in a novel mouse model of Bartonella-induced cat scratch disease results from lymphocyte immigration and proliferation and is regulated by interferon-alpha/beta. |
Volume: |
172 |
Issue: |
4 |
Pages: |
1005-18 |
|
•
•
•
•
•
|
Publication |
First Author: |
Vyas DR |
Year: |
2001 |
Journal: |
J Biol Chem |
Title: |
Multiprotein complex formation at the beta myosin heavy chain distal muscle CAT element correlates with slow muscle expression but not mechanical overload responsiveness. |
Volume: |
276 |
Issue: |
2 |
Pages: |
1173-84 |
|
•
•
•
•
•
|
Publication |
First Author: |
Footz TK |
Year: |
1998 |
Journal: |
Genomics |
Title: |
The gene for death agonist BID maps to the region of human 22q11.2 duplicated in cat eye syndrome chromosomes and to mouse chromosome 6. |
Volume: |
51 |
Issue: |
3 |
Pages: |
472-5 |
|
•
•
•
•
•
|
Publication |
First Author: |
Areda T |
Year: |
2006 |
Journal: |
Behav Brain Res |
Title: |
Cat odour exposure decreases exploratory activity and alters neuropeptide gene expression in CCK(2) receptor deficient mice, but not in their wild-type littermates. |
Volume: |
169 |
Issue: |
2 |
Pages: |
212-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Nagy JI |
Year: |
1999 |
Journal: |
Neuroscience |
Title: |
Connexin30 in rodent, cat and human brain: selective expression in gray matter astrocytes, co-localization with connexin43 at gap junctions and late developmental appearance. |
Volume: |
88 |
Issue: |
2 |
Pages: |
447-68 |
|
•
•
•
•
•
|
Publication |
First Author: |
Thompson PJ |
Year: |
2012 |
Journal: |
J Mol Biol |
Title: |
CECR2 is involved in spermatogenesis and forms a complex with SNF2H in the testis. |
Volume: |
415 |
Issue: |
5 |
Pages: |
793-806 |
|
•
•
•
•
•
|
SO Term |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6437554 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2020-07-06 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:160362 |
Pattern: |
Not Specified |
Stage: |
TS02 |
Assay Id: |
MGI:6437804 |
Age: |
embryonic day 2.0 |
|
Note: |
Colocalization with Cat was demonstrated for some vesicles of 0.5-2.0 diameter. |
Specimen Label: |
4D |
Detected: |
true |
Specimen Num: |
5 |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Strain |
Attribute String: |
coisogenic, endonuclease-mediated mutation, mutant strain |
|
•
•
•
•
•
|
Publication |
First Author: |
Sayles NM |
Year: |
2022 |
Journal: |
Cell Rep |
Title: |
Mutant CHCHD10 causes an extensive metabolic rewiring that precedes OXPHOS dysfunction in a murine model of mitochondrial cardiomyopathy. |
Volume: |
38 |
Issue: |
10 |
Pages: |
110475 |
|
•
•
•
•
•
|
Strain |
Attribute String: |
coisogenic, endonuclease-mediated mutation, mutant strain |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Chchd10/Chchd10 |
Background: |
C57BL/6NJ-Chchd10/J |
Zygosity: |
hm |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
626
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
1425
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Banting GS |
Year: |
2005 |
Journal: |
Hum Mol Genet |
Title: |
CECR2, a protein involved in neurulation, forms a novel chromatin remodeling complex with SNF2L. |
Volume: |
14 |
Issue: |
4 |
Pages: |
513-24 |
|
•
•
•
•
•
|
Allele |
Name: |
cathepsin L; targeted mutation 1, Christoph Peters |
Allele Type: |
Targeted |
Attribute String: |
Null/knockout |
|
•
•
•
•
•
|
Allele |
Name: |
catalase; acatalasemia |
Allele Type: |
Radiation induced |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Anderson CJ |
Year: |
2019 |
Journal: |
Acta Neuropathol |
Title: |
ALS/FTD mutant CHCHD10 mice reveal a tissue-specific toxic gain-of-function and mitochondrial stress response. |
|
|
|
|
•
•
•
•
•
|
Genotype |
Symbol: |
Chchd10/Chchd10<+> |
Background: |
C57BL/6NJ-Chchd10/J |
Zygosity: |
ht |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Publication |
First Author: |
Fairbridge NA |
Year: |
2010 |
Journal: |
Birth Defects Res A Clin Mol Teratol |
Title: |
Cecr2 mutations causing exencephaly trigger misregulation of mesenchymal/ectodermal transcription factors. |
Volume: |
88 |
Issue: |
8 |
Pages: |
619-25 |
|
•
•
•
•
•
|
Publication |
First Author: |
Dawe CE |
Year: |
2011 |
Journal: |
Dev Dyn |
Title: |
Role of chromatin remodeling gene Cecr2 in neurulation and inner ear development. |
Volume: |
240 |
Issue: |
2 |
Pages: |
372-83 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kaiser L |
Year: |
2007 |
Journal: |
J Mol Biol |
Title: |
Structural characterization of the tetrameric form of the major cat allergen Fel d 1. |
Volume: |
370 |
Issue: |
4 |
Pages: |
714-27 |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
GO Term |
|
•
•
•
•
•
|
DO Term |
|
•
•
•
•
•
|
Publication |
First Author: |
Baty C |
Year: |
1998 |
Journal: |
QJM |
Title: |
Familial hypertrophic cardiomyopathy: man, mouse and cat. |
Volume: |
91 |
Issue: |
12 |
Pages: |
791-3 |
|
•
•
•
•
•
|
Publication |
First Author: |
Gaines PJ |
Year: |
2003 |
Journal: |
Insect Biochem Mol Biol |
Title: |
Cloning and characterization of five cDNAs encoding peritrophin-A domains from the cat flea, Ctenocephalides felis. |
Volume: |
33 |
Issue: |
11 |
Pages: |
1061-73 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kaiser L |
Year: |
2003 |
Journal: |
J Biol Chem |
Title: |
The crystal structure of the major cat allergen Fel d 1, a member of the secretoglobin family. |
Volume: |
278 |
Issue: |
39 |
Pages: |
37730-5 |
|
•
•
•
•
•
|
Publication |
First Author: |
Veugelers M |
Year: |
1999 |
Journal: |
J Biol Chem |
Title: |
Glypican-6, a new member of the glypican family of cell surface heparan sulfate proteoglycans. |
Volume: |
274 |
Issue: |
38 |
Pages: |
26968-77 |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Cat/Cat |
Background: |
Not Specified |
Zygosity: |
hm |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
DO Term |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
GO Term |
|
•
•
•
•
•
|
DO Term |
|
•
•
•
•
•
|
Publication |
First Author: |
Southwell N |
Year: |
2024 |
Journal: |
EMBO Mol Med |
Title: |
High fat diet ameliorates mitochondrial cardiomyopathy in CHCHD10 mutant mice. |
Volume: |
16 |
Issue: |
6 |
Pages: |
1352-1378 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhou X |
Year: |
2020 |
Journal: |
EMBO Rep |
Title: |
Loss of Tmem106b exacerbates FTLD pathologies and causes motor deficits in progranulin-deficient mice. |
Volume: |
21 |
Issue: |
10 |
Pages: |
e50197 |
|
•
•
•
•
•
|
Allele |
Name: |
transgene insertion 1, Iichiro Shimomura |
Allele Type: |
Transgenic |
Attribute String: |
Inserted expressed sequence |
|
•
•
•
•
•
|
Allele |
Name: |
transgene insertion 5-2, Shinobu C Fujita |
Allele Type: |
Transgenic |
Attribute String: |
Inserted expressed sequence, Reporter |
|
•
•
•
•
•
|
Allele |
Name: |
transgene insertion 5-7, Shinobu C Fujita |
Allele Type: |
Transgenic |
Attribute String: |
Inserted expressed sequence, Reporter |
|
•
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Allele |
Name: |
transgene insertion 5-8, Shinobu C Fujita |
Allele Type: |
Transgenic |
Attribute String: |
Inserted expressed sequence, Reporter |
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Allele |
Name: |
transgene insertion 5-5, Shinobu C Fujita |
Allele Type: |
Transgenic |
Attribute String: |
Inserted expressed sequence, Reporter |
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Allele |
Name: |
transgene insertion 1, Masato Kasuga |
Allele Type: |
Transgenic |
Attribute String: |
Inserted expressed sequence, Reporter |
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Publication |
First Author: |
Callera GE |
Year: |
2016 |
Journal: |
Biosci Rep |
Title: |
Differential renal effects of candesartan at high and ultra-high doses in diabetic mice-potential role of the ACE2/AT2R/Mas axis. |
Volume: |
36 |
Issue: |
5 |
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Publication |
First Author: |
Neves KB |
Year: |
2018 |
Journal: |
Am J Physiol Heart Circ Physiol |
Title: |
Chemerin receptor blockade improves vascular function in diabetic obese mice via redox-sensitive and Akt-dependent pathways. |
Volume: |
315 |
Issue: |
6 |
Pages: |
H1851-H1860 |
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Publication |
First Author: |
Bruder-Nascimento T |
Year: |
2016 |
Journal: |
PLoS One |
Title: |
Renoprotective Effects of Atorvastatin in Diabetic Mice: Downregulation of RhoA and Upregulation of Akt/GSK3. |
Volume: |
11 |
Issue: |
9 |
Pages: |
e0162731 |
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Publication |
First Author: |
Palais G |
Year: |
2009 |
Journal: |
Physiol Genomics |
Title: |
Targeted transgenesis at the HPRT locus: an efficient strategy to achieve tightly controlled in vivo conditional expression with the tet system. |
Volume: |
37 |
Issue: |
2 |
Pages: |
140-6 |
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Publication |
First Author: |
Sainte-Marie Y |
Year: |
2007 |
Journal: |
FASEB J |
Title: |
Conditional glucocorticoid receptor expression in the heart induces atrio-ventricular block. |
Volume: |
21 |
Issue: |
12 |
Pages: |
3133-41 |
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Publication |
First Author: |
Barrera-Chimal J |
Year: |
2017 |
Journal: |
J Am Soc Nephrol |
Title: |
Benefit of Mineralocorticoid Receptor Antagonism in AKI: Role of Vascular Smooth Muscle Rac1. |
Volume: |
28 |
Issue: |
4 |
Pages: |
1216-1226 |
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