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Search results 401 to 500 out of 547 for Ccl5

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Type Details Score
Publication
23152559 | J:190855
First Author: Schlecker E
Year: 2012
Journal: J Immunol
Title: Tumor-infiltrating monocytic myeloid-derived suppressor cells mediate CCR5-dependent recruitment of regulatory T cells favoring tumor growth.
Volume: 189
Issue: 12
Pages: 5602-11
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16230476 | J:116832
First Author: Glass WG
Year: 2005
Journal: J Exp Med
Title: Chemokine receptor CCR5 promotes leukocyte trafficking to the brain and survival in West Nile virus infection.
Volume: 202
Issue: 8
Pages: 1087-98
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Publication
19050287 | J:142052
First Author: Furuichi K
Year: 2008
Journal: J Immunol
Title: Chemokine receptor CCR1 regulates inflammatory cell infiltration after renal ischemia-reperfusion injury.
Volume: 181
Issue: 12
Pages: 8670-6
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Publication
18250471 | J:131976
First Author: Su YC
Year: 2008
Journal: J Immunol
Title: Granulocyte-macrophage colony-stimulating factor is required for bronchial eosinophilia in a murine model of allergic airway inflammation.
Volume: 180
Issue: 4
Pages: 2600-7
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Publication
30777870 | J:274248
First Author: Sen T
Year: 2019
Journal: Cancer Discov
Title: Targeting DNA Damage Response Promotes Antitumor Immunity through STING-Mediated T-cell Activation in Small Cell Lung Cancer.
Volume: 9
Issue: 5
Pages: 646-661
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Publication
28874687 | J:255437
First Author: Haile LA
Year: 2017
Journal: Sci Rep
Title: Cell based assay identifies TLR2 and TLR4 stimulating impurities in Interferon beta.
Volume: 7
Issue: 1
Pages: 10490
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Publication
36450710 | J:350067
First Author: Chen H
Year: 2022
Journal: Nat Commun
Title: The E3 ubiquitin ligase WWP2 regulates pro-fibrogenic monocyte infiltration and activity in heart fibrosis.
Volume: 13
Issue: 1
Pages: 7375
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Publication
34725110 | J:323059
First Author: Reeves AR
Year: 2021
Journal: J Immunol
Title: Myeloid-Specific Deficiency of Long-Chain Acyl CoA Synthetase 4 Reduces Inflammation by Remodeling Phospholipids and Reducing Production of Arachidonic Acid-Derived Proinflammatory Lipid Mediators.
Volume: 207
Issue: 11
Pages: 2744-2753
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Publication
21948969 | J:178007
First Author: Hong M
Year: 2011
Journal: Cancer Res
Title: Chemotherapy induces intratumoral expression of chemokines in cutaneous melanoma, favoring T-cell infiltration and tumor control.
Volume: 71
Issue: 22
Pages: 6997-7009
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Publication
28515147 | J:242569
First Author: Loveridge CJ
Year: 2017
Journal: Cancer Res
Title: Increased T-cell Infiltration Elicited by Erk5 Deletion in a Pten-Deficient Mouse Model of Prostate Carcinogenesis.
Volume: 77
Issue: 12
Pages: 3158-3168
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Publication
25077938 | J:278271
First Author: McNeill E
Year: 2014
Journal: J Mol Med (Berl)
Title: Contrasting in vitro vs. in vivo effects of a cell membrane-specific CC-chemokine binding protein on macrophage chemotaxis.
Volume: 92
Issue: 11
Pages: 1169-78
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Publication
24147040 | J:209103
First Author: McCarthy MK
Year: 2013
Journal: PLoS One
Title: Prostaglandin E2 induction during mouse adenovirus type 1 respiratory infection regulates inflammatory mediator generation but does not affect viral pathogenesis.
Volume: 8
Issue: 10
Pages: e77628
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Publication
21115617 | J:185887
First Author: Juncos JP
Year: 2011
Journal: J Am Soc Nephrol
Title: MCP-1 contributes to arteriovenous fistula failure.
Volume: 22
Issue: 1
Pages: 43-8
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21469130 | J:175404
First Author: He G
Year: 2011
Journal: Eur J Immunol
Title: Role of CLIC4 in the host innate responses to bacterial lipopolysaccharide.
Volume: 41
Issue: 5
Pages: 1221-30
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Publication
29208683 | J:259095
 
First Author: Serrels B
Year: 2017
Journal: Sci Signal
Title: IL-33 and ST2 mediate FAK-dependent antitumor immune evasion through transcriptional networks.
Volume: 10
Issue: 508
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15661900 | J:96414
First Author: Atarashi K
Year: 2005
Journal: J Immunol
Title: Rolling of Th1 cells via P-selectin glycoprotein ligand-1 stimulates LFA-1-mediated cell binding to ICAM-1.
Volume: 174
Issue: 3
Pages: 1424-32
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Publication
18931326 | J:159270
First Author: Reppe K
Year: 2009
Journal: Am J Respir Cell Mol Biol
Title: Immunostimulation with macrophage-activating lipopeptide-2 increased survival in murine pneumonia.
Volume: 40
Issue: 4
Pages: 474-81
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21925471 | J:177368
First Author: Krauthausen M
Year: 2011
Journal: Am J Pathol
Title: Opposing roles for CXCR3 signaling in central nervous system versus ocular inflammation mediated by the astrocyte-targeted production of IL-12.
Volume: 179
Issue: 5
Pages: 2346-59
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18178862 | J:130981
First Author: Miu J
Year: 2008
Journal: J Immunol
Title: Chemokine gene expression during fatal murine cerebral malaria and protection due to CXCR3 deficiency.
Volume: 180
Issue: 2
Pages: 1217-30
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22904301 | J:189917
First Author: Gantner BN
Year: 2012
Journal: J Immunol
Title: The Akt1 isoform is required for optimal IFN-β transcription through direct phosphorylation of β-catenin.
Volume: 189
Issue: 6
Pages: 3104-11
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Publication
36631487 | J:352075
First Author: Li J
Year: 2023
Journal: Nat Commun
Title: TGFβ1(+)CCR5(+) neutrophil subset increases in bone marrow and causes age-related osteoporosis in male mice.
Volume: 14
Issue: 1
Pages: 159
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24820540 | J:214332
 
First Author: Noh MY
Year: 2014
Journal: Neurosci Lett
Title: Erythropoietin modulates the immune-inflammatory response of a SOD1(G93A) transgenic mouse model of amyotrophic lateral sclerosis (ALS).
Volume: 574
Pages: 53-8
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24311453 | J:207161
First Author: Tönges L
Year: 2014
Journal: Glia
Title: Rho kinase inhibition modulates microglia activation and improves survival in a model of amyotrophic lateral sclerosis.
Volume: 62
Issue: 2
Pages: 217-32
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37741861 | J:341208
First Author: Ishi S
Year: 2023
Journal: Sci Rep
Title: Cutaneous wound healing promoted by topical administration of heat-killed Lactobacillus plantarum KB131 and possible contribution of CARD9-mediated signaling.
Volume: 13
Issue: 1
Pages: 15917
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17705131 | J:124337
First Author: Werts C
Year: 2007
Journal: Eur J Immunol
Title: Nod1 and Nod2 induce CCL5/RANTES through the NF-kappaB pathway.
Volume: 37
Issue: 9
Pages: 2499-508
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22588539 | J:283959
First Author: Liu Z
Year: 2012
Journal: Transplantation
Title: Deletion of CD98 heavy chain in T cells results in cardiac allograft acceptance by increasing regulatory T cells.
Volume: 93
Issue: 11
Pages: 1116-24
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Publication
23340313 | J:194059
First Author: Leongson K
Year: 2013
Journal: Infect Immun
Title: Altered immune response differentially enhances susceptibility to Cryptococcus neoformans and Cryptococcus gattii infection in mice expressing the HIV-1 transgene.
Volume: 81
Issue: 4
Pages: 1100-13
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Publication
33310873 | J:303886
First Author: Yamana T
Year: 2021
Journal: J Immunol
Title: IL-17A-Secreting Memory γδ T Cells Play a Pivotal Role in Sensitization and Development of Hypersensitivity Pneumonitis.
Volume: 206
Issue: 2
Pages: 355-365
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Publication
20299361 | J:185841
First Author: Gan PY
Year: 2010
Journal: J Am Soc Nephrol
Title: Th17 cells promote autoimmune anti-myeloperoxidase glomerulonephritis.
Volume: 21
Issue: 6
Pages: 925-31
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Publication
24425712 | J:204203
First Author: Döring Y
Year: 2014
Journal: Circ Res
Title: Deficiency of the sialyltransferase St3Gal4 reduces Ccl5-mediated myeloid cell recruitment and arrest: short communication.
Volume: 114
Issue: 6
Pages: 976-81
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Publication
21228116 | J:205229
First Author: Ichikawa M
Year: 2011
Journal: Mol Cancer Res
Title: S100A8/A9 activate key genes and pathways in colon tumor progression.
Volume: 9
Issue: 2
Pages: 133-48
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Publication
24920846 | J:357959
First Author: Zhao C
Year: 2014
Journal: J Immunol
Title: Cellular stress amplifies TLR3/4-induced CXCL1/2 gene transcription in mononuclear phagocytes via RIPK1.
Volume: 193
Issue: 2
Pages: 879-88
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Publication
22006569 | J:178963
First Author: Derbigny WA
Year: 2012
Journal: Infect Immun
Title: Identifying a role for Toll-like receptor 3 in the innate immune response to Chlamydia muridarum infection in murine oviduct epithelial cells.
Volume: 80
Issue: 1
Pages: 254-65
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Publication
27977747 | J:251400
First Author: Jörger AK
Year: 2016
Journal: PLoS One
Title: Impact of NKT Cells and LFA-1 on Liver Regeneration under Subseptic Conditions.
Volume: 11
Issue: 12
Pages: e0168001
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Publication
32785693 | J:347645
 
First Author: Principe M
Year: 2020
Journal: J Clin Endocrinol Metab
Title: Immune Landscape of Pituitary Tumors Reveals Association Between Macrophages and Gonadotroph Tumor Invasion.
Volume: 105
Issue: 11
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Publication
34659202 | J:312701
 
First Author: Scheunemann JF
Year: 2021
Journal: Front Immunol
Title: Eosinophils Suppress the Migration of T Cells Into the Brain of Plasmodium berghei-Infected Ifnar1-/- Mice and Protect Them From Experimental Cerebral Malaria.
Volume: 12
Pages: 711876
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20720199 | J:163545
First Author: Carrigan SO
Year: 2010
Journal: J Immunol
Title: IFN regulatory factor 3 contributes to the host response during Pseudomonas aeruginosa lung infection in mice.
Volume: 185
Issue: 6
Pages: 3602-9
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Publication
21338585 | J:170463
 
First Author: Rodrigues DH
Year: 2011
Journal: Brain Res
Title: Absence of PAF receptor alters cellular infiltrate but not rolling and adhesion of leukocytes in experimental autoimmune encephalomyelitis.
Volume: 1385
Pages: 298-306
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Publication
29099969 | J:249497
First Author: Ito T
Year: 2017
Journal: Int Immunol
Title: Anti-tumor immunity via the superoxide-eosinophil axis induced by a lipophilic component of Mycobacterium lipomannan.
Volume: 29
Issue: 9
Pages: 411-421
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Publication
26244295 | J:230945
First Author: Asada Y
Year: 2015
Journal: Invest Ophthalmol Vis Sci
Title: Roles of Epithelial Cell-Derived Type 2-Initiating Cytokines in Experimental Allergic Conjunctivitis.
Volume: 56
Issue: 9
Pages: 5194-202
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15226319 | J:92853
First Author: Inouye S
Year: 2004
Journal: J Biol Chem
Title: Impaired IgG production in mice deficient for heat shock transcription factor 1.
Volume: 279
Issue: 37
Pages: 38701-9
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34440764 | J:312540
 
First Author: Coenen DM
Year: 2021
Journal: Cells
Title: Inhibition of Phosphodiesterase 3A by Cilostazol Dampens Proinflammatory Platelet Functions.
Volume: 10
Issue: 8
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Publication
22469976 | J:193367
First Author: Arabzadeh A
Year: 2013
Journal: Oncogene
Title: Host-related carcinoembryonic antigen cell adhesion molecule 1 promotes metastasis of colorectal cancer.
Volume: 32
Issue: 7
Pages: 849-60
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Publication
28373218 | J:265109
First Author: Mogler C
Year: 2017
Journal: EMBO Mol Med
Title: Hepatic stellate cells limit hepatocellular carcinoma progression through the orphan receptor endosialin.
Volume: 9
Issue: 6
Pages: 741-749
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Publication
22952118 | J:214279
First Author: Bryant-Hudson KM
Year: 2012
Journal: Invest Ophthalmol Vis Sci
Title: CXCL1-deficient mice are highly sensitive to pseudomonas aeruginosa but not herpes simplex virus type 1 corneal infection.
Volume: 53
Issue: 11
Pages: 6785-92
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Publication
26305961 | J:226808
First Author: Hu C
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: NLRP3 deficiency protects from type 1 diabetes through the regulation of chemotaxis into the pancreatic islets.
Volume: 112
Issue: 36
Pages: 11318-23
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Publication
29627569 | J:272473
First Author: Takashima K
Year: 2018
Journal: Biochem Biophys Res Commun
Title: TICAM-1 is dispensable in STING-mediated innate immune responses in myeloid immune cells.
Volume: 499
Issue: 4
Pages: 985-991
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Publication
22513871 | J:187022
First Author: Uzhachenko R
Year: 2012
Journal: J Pathol
Title: Tumour suppressor Fus1 provides a molecular link between inflammatory response and mitochondrial homeostasis.
Volume: 227
Issue: 4
Pages: 456-69
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Publication
26235435 | J:226267
 
First Author: Lonskaya I
Year: 2015
Journal: Neuroscience
Title: Nilotinib and bosutinib modulate pre-plaque alterations of blood immune markers and neuro-inflammation in Alzheimer's disease models.
Volume: 304
Pages: 316-27
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Publication
22986739 | J:192888
First Author: Chow MT
Year: 2012
Journal: Cancer Res
Title: NLRP3 suppresses NK cell-mediated responses to carcinogen-induced tumors and metastases.
Volume: 72
Issue: 22
Pages: 5721-32
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Publication
22665935 | J:189100
First Author: Randriamboavonjy V
Year: 2012
Journal: Blood
Title: Calpain inhibition stabilizes the platelet proteome and reactivity in diabetes.
Volume: 120
Issue: 2
Pages: 415-23
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32708944 | J:304509
 
First Author: Pease NA
Year: 2020
Journal: Cancers (Basel)
Title: DEK Expression in Breast Cancer Cells Leads to the Alternative Activation of Tumor Associated Macrophages.
Volume: 12
Issue: 7
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Publication
31491449 | J:279383
 
First Author: Voshtani R
Year: 2019
Journal: Cancer Lett
Title: Progranulin promotes melanoma progression by inhibiting natural killer cell recruitment to the tumor microenvironment.
Volume: 465
Pages: 24-35
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Publication
31805036 | J:287862
First Author: Wang Z
Year: 2019
Journal: PLoS Biol
Title: Mediator MED23 regulates inflammatory responses and liver fibrosis.
Volume: 17
Issue: 12
Pages: e3000563
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27583382 | J:251341
First Author: Ringling RE
Year: 2016
Journal: PLoS One
Title: Loss of Nlrp3 Does Not Protect Mice from Western Diet-Induced Adipose Tissue Inflammation and Glucose Intolerance.
Volume: 11
Issue: 9
Pages: e0161939
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Publication
32816906 | J:296662
First Author: Wang Q
Year: 2020
Journal: Cancer Res
Title: ARC Is a Critical Protector against Inflammatory Bowel Disease (IBD) and IBD-Associated Colorectal Tumorigenesis.
Volume: 80
Issue: 19
Pages: 4158-4171
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23082204 | J:192198
First Author: Soberman RJ
Year: 2012
Journal: PLoS One
Title: CD200R1 supports HSV-1 viral replication and licenses pro-inflammatory signaling functions of TLR2.
Volume: 7
Issue: 10
Pages: e47740
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Publication
30450923 | J:314439
First Author: Stevenson MD
Year: 2019
Journal: Antioxid Redox Signal
Title: NADPH Oxidase 4 Regulates Inflammation in Ischemic Heart Failure: Role of Soluble Epoxide Hydrolase.
Volume: 31
Issue: 1
Pages: 39-58
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30643968 | J:295076
First Author: Kröller-Schön S
Year: 2019
Journal: Basic Res Cardiol
Title: Endothelial α1AMPK modulates angiotensin II-mediated vascular inflammation and dysfunction.
Volume: 114
Issue: 2
Pages: 8
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36978267 | J:338012
First Author: Speidell A
Year: 2023
Journal: J Neurochem
Title: Mice deficient for G-protein-coupled receptor 75 display altered presynaptic structural protein expression and disrupted fear conditioning recall.
Volume: 165
Issue: 6
Pages: 827-841
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35365562 | J:325487
First Author: Robinson EK
Year: 2022
Journal: J Immunol
Title: lincRNA-Cox2 Functions to Regulate Inflammation in Alveolar Macrophages during Acute Lung Injury.
Volume: 208
Issue: 8
Pages: 1886-1900
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16002730 | J:100737
First Author: Ali S
Year: 2005
Journal: J Immunol
Title: A non-glycosaminoglycan-binding variant of CC chemokine ligand 7 (monocyte chemoattractant protein-3) antagonizes chemokine-mediated inflammation.
Volume: 175
Issue: 2
Pages: 1257-66
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Publication
16368965 | J:104278
First Author: Hardison JL
Year: 2006
Journal: Infect Immun
Title: The chemokines CXCL9 and CXCL10 promote a protective immune response but do not contribute to cardiac inflammation following infection with Trypanosoma cruzi.
Volume: 74
Issue: 1
Pages: 125-34
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17314297 | J:118375
First Author: Balabanov R
Year: 2007
Journal: J Neurosci
Title: Interferon-gamma-oligodendrocyte interactions in the regulation of experimental autoimmune encephalomyelitis.
Volume: 27
Issue: 8
Pages: 2013-24
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17389363 | J:120362
First Author: Lunzer MM
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: Naloxone acts as a potent analgesic in transgenic mouse models of sickle cell anemia.
Volume: 104
Issue: 14
Pages: 6061-5
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16670311 | J:131703
First Author: Hu Y
Year: 2006
Journal: J Immunol
Title: Costimulation of chemokine receptor signaling by matrix metalloproteinase-9 mediates enhanced migration of IFN-alpha dendritic cells.
Volume: 176
Issue: 10
Pages: 6022-33
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Publication
18250418 | J:131921
First Author: Xu XJ
Year: 2008
Journal: J Immunol
Title: Prostaglandin E2 suppresses lipopolysaccharide-stimulated IFN-beta production.
Volume: 180
Issue: 4
Pages: 2125-31
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Publication
18713987 | J:138956
First Author: Qin H
Year: 2008
Journal: J Immunol
Title: Expression and functional significance of SOCS-1 and SOCS-3 in astrocytes.
Volume: 181
Issue: 5
Pages: 3167-76
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Publication
19582753 | J:150261
First Author: Ranasinghe C
Year: 2009
Journal: Eur J Immunol
Title: Immunisation route-dependent expression of IL-4/IL-13 can modulate HIV-specific CD8(+) CTL avidity.
Volume: 39
Issue: 7
Pages: 1819-30
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17878349 | J:152351
First Author: Zhai Y
Year: 2007
Journal: J Immunol
Title: Defective alloreactive CD8 T cell function and memory response in allograft recipients in the absence of CD4 help.
Volume: 179
Issue: 7
Pages: 4529-34
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19933834 | J:157788
First Author: Ribes S
Year: 2010
Journal: Infect Immun
Title: Toll-like receptor stimulation enhances phagocytosis and intracellular killing of nonencapsulated and encapsulated Streptococcus pneumoniae by murine microglia.
Volume: 78
Issue: 2
Pages: 865-71
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20557428 | J:164263
First Author: van Neerven S
Year: 2010
Journal: J Neurochem
Title: Inflammatory chemokine release of astrocytes in vitro is reduced by all-trans retinoic acid.
Volume: 114
Issue: 5
Pages: 1511-26
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20650880 | J:168368
First Author: Ilievski V
Year: 2010
Journal: Biol Reprod
Title: Synergy between viral and bacterial toll-like receptors leads to amplification of inflammatory responses and preterm labor in the mouse.
Volume: 83
Issue: 5
Pages: 767-73
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21131443 | J:186819
First Author: Reynolds PR
Year: 2011
Journal: Am J Respir Cell Mol Biol
Title: Receptor for advanced glycation end-products signals through Ras during tobacco smoke-induced pulmonary inflammation.
Volume: 45
Issue: 2
Pages: 411-8
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Publication
23000264 | J:190091
First Author: Szczepanek SM
Year: 2012
Journal: Am J Pathol
Title: Splenic morphological changes are accompanied by altered baseline immunity in a mouse model of sickle-cell disease.
Volume: 181
Issue: 5
Pages: 1725-34
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Publication
22962436 | J:191112
First Author: Götlind YY
Year: 2013
Journal: Int Immunol
Title: Interplay between T(h)1 and T(h)17 effector T-cell pathways in the pathogenesis of spontaneous colitis and colon cancer in the Gαi2-deficient mouse.
Volume: 25
Issue: 1
Pages: 35-44
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25211222 | J:223416
First Author: Shevlin E
Year: 2014
Journal: PLoS One
Title: The TIR-domain containing adaptor TRAM is required for TLR7 mediated RANTES production.
Volume: 9
Issue: 9
Pages: e107141
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Publication
37742819 | J:358277
 
First Author: D'Addario CA
Year: 2023
Journal: Vascul Pharmacol
Title: Global and endothelial G-protein coupled receptor 75 (GPR75) knockout relaxes pulmonary artery and mitigates hypoxia-induced pulmonary hypertension.
Volume: 153
Pages: 107235
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Publication
25986989 | J:253877
First Author: Manning BM
Year: 2015
Journal: Biochim Biophys Acta
Title: Single-cell analysis of mast cell degranulation induced by airway smooth muscle-secreted chemokines.
Volume: 1850
Issue: 9
Pages: 1862-8
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Publication
28784845 | J:254751
First Author: Jongstra-Bilen J
Year: 2017
Journal: J Immunol
Title: Oxidized Low-Density Lipoprotein Loading of Macrophages Downregulates TLR-Induced Proinflammatory Responses in a Gene-Specific and Temporal Manner through Transcriptional Control.
Volume: 199
Issue: 6
Pages: 2149-2157
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Publication
31186238 | J:278169
First Author: Ruiz de Galarreta M
Year: 2019
Journal: Cancer Discov
Title: β-Catenin Activation Promotes Immune Escape and Resistance to Anti-PD-1 Therapy in Hepatocellular Carcinoma.
Volume: 9
Issue: 8
Pages: 1124-1141
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Publication
31040394 | J:295782
First Author: Xia C
Year: 2019
Journal: Int J Obes (Lond)
Title: MRP14 enhances the ability of macrophage to recruit T cells and promotes obesity-induced insulin resistance.
Volume: 43
Issue: 12
Pages: 2434-2447
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32948682 | J:303625
First Author: Davenport B
Year: 2020
Journal: J Immunol
Title: Chemokine Signatures of Pathogen-Specific T Cells II: Memory T Cells in Acute and Chronic Infection.
Volume: 205
Issue: 8
Pages: 2188-2206
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Publication
25488987 | J:319066
First Author: Kanno S
Year: 2015
Journal: J Immunol
Title: Activation of an innate immune receptor, Nod1, accelerates atherogenesis in Apoe-/- mice.
Volume: 194
Issue: 2
Pages: 773-80
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25104056 | J:340843
First Author: Koltsova EK
Year: 2014
Journal: Thromb Haemost
Title: Genetic deletion of platelet glycoprotein Ib alpha but not its extracellular domain protects from atherosclerosis.
Volume: 112
Issue: 6
Pages: 1252-63
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Publication
28610763 | J:338740
First Author: Bernhardt A
Year: 2017
Journal: Kidney Int
Title: Inflammatory cell infiltration and resolution of kidney inflammation is orchestrated by the cold-shock protein Y-box binding protein-1.
Volume: 92
Issue: 5
Pages: 1157-1177
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37395684 | J:340271
First Author: Ka NL
Year: 2023
Journal: Cancer Res
Title: NR1D1 Stimulates Antitumor Immune Responses in Breast Cancer by Activating cGAS-STING Signaling.
Volume: 83
Issue: 18
Pages: 3045-3058
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Publication
37945689 | J:342434
First Author: Solomon OD
Year: 2023
Journal: Sci Rep
Title: Dynamic intravital imaging reveals reactive vessel-associated microglia play a protective role in cerebral malaria coagulopathy.
Volume: 13
Issue: 1
Pages: 19526
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8663314 | J:45024
First Author: Raport CJ
Year: 1996
Journal: J Biol Chem
Title: Molecular cloning and functional characterization of a novel human CC chemokine receptor (CCR5) for RANTES, MIP-1beta, and MIP-1alpha.
Volume: 271
Issue: 29
Pages: 17161-6
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Publication
9655467 | -
First Author: Jiang Y
Year: 1998
Journal: J Neuroimmunol
Title: Chemokine receptor expression in cultured glia and rat experimental allergic encephalomyelitis.
Volume: 86
Issue: 1
Pages: 1-12
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Publication
11994538 | -
First Author: Habasque C
Year: 2002
Journal: Mol Hum Reprod
Title: Study of the HIV-1 receptors CD4, CXCR4, CCR5 and CCR3 in the human and rat testis.
Volume: 8
Issue: 5
Pages: 419-25
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12682253 | -
First Author: Ng-Cashin J
Year: 2003
Journal: J Immunol
Title: Host absence of CCR5 potentiates dendritic cell vaccination.
Volume: 170
Issue: 8
Pages: 4201-8
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Protein Domain
IPR002240 | Chemokine_CCR5
Type: Family
Description: CC chemokine receptor 5 (CCR5) is found on the surface of white blood cells, such as macrophages [], T cells []and dendritic cells [, ], and expressed in lymphoid organs []. Transfected cells expressing CCR5 receptor bind CCL5 (RANTES), CCL4 (MIP-1beta) and CCL3 (MIP-1alpha), and generate inositol phosphates in response to these chemokines. The same combination of chemokines has been shown to potently inhibit human immunodeficiency virus replication in human peripheral blood leukocytes []. CCR5 is the major coreceptor for HIV-1 entry into target cells and is thought to be a suitable therapeutic target for HIV-1 blockade [].Chemokines (chemotactic cytokines) are a family of chemoattractant molecules. They attract leukocytes to areas of inflammation and lesions, and play a key role in leukocyte activation. Originally defined as host defense proteins, chemokines are now known to play a much broader biological role []. They have a wide range of effects in many different cell types beyond the immune system, including, for example, various cells of the central nervous system [], and endothelial cells, where they may act as either angiogenic or angiostatic factors [].The chemokine family is divided into four classes based on the number and spacing of their conserved cysteines: 2 Cys residues may be adjacent (the CC family); separated by an intervening residue (the CXC family); have only one of the first two Cys residues (C chemokines); or contain both cysteines, separated by three intervening residues (CX3C chemokines).Chemokines exert their effects by binding to rhodopsin-like G protein-coupled receptors on the surface of cells. Following interaction with their specific chemokine ligands, chemokine receptors trigger a flux in intracellular calcium ions, which cause a cellular response, including the onset of chemotaxis. There are over fifty distinct chemokines and least 18 human chemokine receptors []. Although the receptors bind only a single class of chemokines, they often bind several members of the same class with high affinity. Chemokine receptors are preferentially expressed on important functional subsets of dendritic cells, monocytes and lymphocytes, including Langerhans cells and T helper cells [, ]. Chemokines and their receptors can also be subclassified into homeostatic leukocyte homing molecules (CXCR4, CXCR5, CCR7, CCR9) versus inflammatory/inducible molecules (CXCR1, CXCR2, CXCR3, CCR1-6, CX3CR1).CC chemokine receptors are a subfamily of the chemokine receptors that specifically bind and respond to cytokines of the CC chemokine family. There are currently ten members of the CC chemokine receptor subfamily, named CCR1 to 10. The receptors receptors are found in monocytes, lymphocytes, basophils and eosinophils.
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Publication
27283745 | J:247005
First Author: Martorell S
Year: 2016
Journal: Arterioscler Thromb Vasc Biol
Title: Vitamin D Receptor Activation Reduces Angiotensin-II-Induced Dissecting Abdominal Aortic Aneurysm in Apolipoprotein E-Knockout Mice.
Volume: 36
Issue: 8
Pages: 1587-97
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Publication
25767273 | J:241334
First Author: Ebrahimian T
Year: 2015
Journal: Arterioscler Thromb Vasc Biol
Title: Absence of Four-and-a-Half LIM Domain Protein 2 Decreases Atherosclerosis in ApoE-/- Mice.
Volume: 35
Issue: 5
Pages: 1190-7
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Publication
22696658 | J:328831
First Author: Earl PL
Year: 2012
Journal: J Virol
Title: Lethal monkeypox virus infection of CAST/EiJ mice is associated with a deficient gamma interferon response.
Volume: 86
Issue: 17
Pages: 9105-12
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Publication
16634801 | J:108129
First Author: Sheil B
Year: 2006
Journal: Clin Exp Immunol
Title: Role of interleukin (IL-10) in probiotic-mediated immune modulation: an assessment in wild-type and IL-10 knock-out mice.
Volume: 144
Issue: 2
Pages: 273-80
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Publication
33117286 | J:312576
 
First Author: Amorim NRT
Year: 2020
Journal: Front Endocrinol (Lausanne)
Title: Leptin Elicits In Vivo Eosinophil Migration and Activation: Key Role of Mast Cell-Derived PGD2.
Volume: 11
Pages: 572113
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Publication
25253732 | J:218423
First Author: Agrawal V
Year: 2014
Journal: Biol Reprod
Title: Platelet-activating factor: a role in preterm delivery and an essential interaction with Toll-like receptor signaling in mice.
Volume: 91
Issue: 5
Pages: 119
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Publication
19019963 | J:153388
First Author: Murawski MR
Year: 2009
Journal: J Virol
Title: Respiratory syncytial virus activates innate immunity through Toll-like receptor 2.
Volume: 83
Issue: 3
Pages: 1492-500
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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