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Search results 401 to 483 out of 483 for Cd38

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Type Details Score
Allele
Cd38<+> | MGI:2433789
   
Name: CD38 antigen; wild type
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Interaction Experiment
Cho YS (2000)
Description: Direct interaction of the CD38 cytoplasmic tail and the Lck SH2 domain. Cd38 transduces T cell activation signals through associated Lck.
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Strain
MGI:7751756 | C57BL/6JSmoc-Cd38<em2(CD38)Smoc> In(9CD3D,CD3E,CD3G)1Smoc/Smoc
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Strain
MGI:6770631 | C57BL/6JSmoc-Cd28<em2(CD28)Smoc> Cd38<em2(CD38)Smoc>/Smoc
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Strain
MGI:6770636 | C57BL/6JSmoc-Cd38<em2(CD38)Smoc> Cd3e<em6(CD3E)Smoc>/Smoc
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Publication
15728476 | J:97713
First Author: Moreno-GarcĂ­a ME
Year: 2005
Journal: J Immunol
Title: CD38 signaling regulates B lymphocyte activation via a phospholipase C (PLC)-gamma 2-independent, protein kinase C, phosphatidylcholine-PLC, and phospholipase D-dependent signaling cascade.
Volume: 174
Issue: 5
Pages: 2687-95
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Publication
8524855 | J:30161
First Author: Kikuchi Y
Year: 1995
Journal: Proc Natl Acad Sci U S A
Title: CD38 ligation induces tyrosine phosphorylation of Bruton tyrosine kinase and enhanced expression of interleukin 5-receptor alpha chain: synergistic effects with interleukin 5.
Volume: 92
Issue: 25
Pages: 11814-8
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Allele
Cd38<tm1Okam> | MGI:2680868
Name: CD38 antigen; targeted mutation 1, Hiroshi Okamoto
Allele Type: Targeted
Attribute String: Null/knockout
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Allele
Cd38<Gt(OST329112)Lex> | MGI:4282378
 
Name: CD38 antigen; gene trap OST329112, Lexicon Genetics
Allele Type: Gene trapped
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Allele
Cd38<em1Cya> | MGI:6835766
Name: CD38 antigen; endonuclease-mediated mutation 1, Cyagen Biosciences
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
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Allele
Cd38<tm1Thir> | MGI:7526310
Name: CD38 antigen; targeted mutation 1, Toshio Hirano
Allele Type: Targeted
Attribute String: Null/knockout
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Allele
Cd38<em3(CD38)Gpt> | MGI:7576272
Name: CD38 antigen; endonuclease-mediated mutation 3, GemPharmatech
Allele Type: Endonuclease-mediated
Attribute String: Humanized sequence, Inserted expressed sequence
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Allele
Cd38<em2Cya> | MGI:7582851
Name: CD38 antigen; endonuclease-mediated mutation 2, Cyagen Biosciences
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
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Allele
Cd38<em3Cya> | MGI:7792581
Name: CD38 antigen; endonuclease-mediated mutation 3, Cyagen Biosciences
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Allele
Cd38<tm1Lnd> | MGI:1861803
Name: CD38 antigen; targeted mutation 1, Frances E Lund
Allele Type: Targeted
Attribute String: Null/knockout
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Strain
MGI:3762938 | B6.Cg-Cd38<tm1Okam>/OkamRbrc
Attribute String: mutant strain, targeted mutation
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Allele
Cd38<Gt(EUCE0073h03)Hmgu> | MGI:4376226
 
Name: CD38 antigen; gene trap EUCE0073h03, Helmholtz Zentrum Muenchen GmbH
Allele Type: Gene trapped
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Allele
Cd38<tm1(NCOM)Mfgc> | MGI:4880351
Name: CD38 antigen; targeted mutation 1, Mammalian Functional Genomics Centre
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
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Allele
Cd38<tm1a(EUCOMM)Hmgu> | MGI:4950992
Name: CD38 antigen; targeted mutation 1a, Helmholtz Zentrum Muenchen GmbH
Allele Type: Targeted
Attribute String: Conditional ready, Null/knockout, Reporter
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Allele
Cd38<tm1e(EUCOMM)Hmgu> | MGI:4951078
Name: CD38 antigen; targeted mutation 1e, Helmholtz Zentrum Muenchen GmbH
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
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Allele
Cd38<em1(IMPC)Ccpcz> | MGI:6385272
Name: CD38 antigen; endonuclease-mediated mutation 1, Institute of Molecular Genetics
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Allele
Cd38<em1Gpt> | MGI:7296580
Name: CD38 antigen; endonuclease-mediated mutation 1, GemPharmatech Co., Ltd
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
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Allele
Cd38<em7Gpt> | MGI:7296581
Name: CD38 antigen; endonuclease-mediated mutation 7, GemPharmatech Co., Ltd
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Allele
Cd38<em2(CD38)Gpt> | MGI:7376324
Name: CD38 antigen; endonuclease-mediated mutation 2, GemPharmatech Co., Ltd
Allele Type: Endonuclease-mediated
Attribute String: Inserted expressed sequence
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Strain
MGI:7588171 | C57BL/6J-Cd38<em2Cya>/Cya
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Allele
Cd38<em4Smoc> | MGI:7750463
Name: CD38 antigen; endonuclease-mediated mutation 4, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Strain
MGI:7836900 | C57BL/6N-Cd38<em3Cya>/Cya
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Genotype
Genotype
Symbol: Cd38/Cd38
Background: involves: C57BL/6 * CBA
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Cd38/Cd38
Background: involves: 129P2/OlaHsd * C57BL/6
Zygosity: hm
Has Mutant Allele: true
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Strain
MGI:7751757 | C57BL/6JSmoc-Cd28<em2(CD28)Smoc> Cd38<em2(hCD38)Smoc> In(9CD3D,CD3E,CD3G)1Smoc/Smoc
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Strain
MGI:7718259 | C57BL/6JSmoc-Sirpa<tm2(SIRPA)Smoc> Cd38<em2(CD38)Smoc> Cd47<em2(CD47)Smoc>/Smoc
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Strain
MGI:2174115 | B6.129P2-Cd38<tm1Lnd>/J
Attribute String: congenic, mutant strain, targeted mutation
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Strain
MGI:3757553 | B6.129P2-Cd38<tm1Lnd>
Attribute String: congenic, mutant strain, targeted mutation
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Strain
MGI:2174300 | NOD.129P2(B6)-Cd38<tm1Lnd>/LtJ
Attribute String: congenic, mutant strain, targeted mutation
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Strain
MGI:7414533 | C57BL/6NCrl-Cd38<em1(IMPC)Ccpcz>/Ccpcz
Attribute String: coisogenic
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Strain
MGI:7853158 | C57BL/6NCrl-Cd38<em1(IMPC)Ccpcz>/Ph
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Strain
MGI:6767315 | C57BL/6JGpt-Cd38<em7Gpt>/Gpt
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
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Strain
MGI:7381336 | C57BL/6JGpt-Cd38<em2(CD38)Gpt>/Gpt
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
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Strain
MGI:7764330 | C57BL/6JSmoc-Cd38<em4Smoc>/Smoc
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Genotype
Genotype
Symbol: Cd38/Cd38
Background: involves: 129P2/OlaHsd * C57BL/6J
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Cd38/Cd38
Background: NOD.129P2(B6)-Cd38/LtJ
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Cd38/Cd38
Background: B6.129P2-Cd38
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Cd38/Cd38
Background: C57BL/6NCrl-Cd38/Ccpcz
Zygosity: hm
Has Mutant Allele: true
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CL Term
CL:4033065 | preplasmablast
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Strain
MGI:3662638 | NOD.Cg-Cd38<tm1Lnd> Prkdc<scid>/LtJ
Attribute String: targeted mutation, spontaneous mutation, mutant strain, congenic
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Strain
MGI:6353158 | B6.129P2-Bst1<tm2Thir> Cd38<tm1Thir>/ThirRbrc
Attribute String: targeted mutation, congenic, mutant strain
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Publication
10636863 | -
First Author: Cho YS
Year: 2000
Journal: J Biol Chem
Title: Direct interaction of the CD38 cytoplasmic tail and the Lck SH2 domain. Cd38 transduces T cell activation signals through associated Lck.
Volume: 275
Issue: 3
Pages: 1685-90
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Strain
MGI:3623982 | NOD.129(B6)-Cd38<tm1Lnd> Art2a<tm1Fkn> Art2b<tm1Fkn>/Lt
Attribute String: congenic, mutant strain, targeted mutation
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Strain
MGI:7577298 | BALB/cJGpt-Pdcd1<em2(PDCD1)Gpt> Cd38<em3(CD38)Gpt> Cd274<tm2(CD274)Gpt>/Gpt
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Genotype
Genotype
Symbol: Art2a/Art2a Art2b/Art2b Cd38/Cd38
Background: NOD.129(B6)-Cd38 Art2a Art2b/Lt
Zygosity: cx
Has Mutant Allele: true
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Protein
Q64277
Organism: Mus musculus/domesticus
Length: 311  
Fragment?: false
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Protein
Q3TPZ1
Organism: Mus musculus/domesticus
Length: 182  
Fragment?: false
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Protein
A0A0R4J190
Organism: Mus musculus/domesticus
Length: 311  
Fragment?: false
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Protein Domain
IPR003193 | ADP-ribosyl_cyclase
Type: Family
Description: CD38, the HUGO gene name, is also called T10 or ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase (). CD38 is a novel enzyme capable of catalysing multiple reactions, including NAD glycohydrolase, ADP-ribosyl cyclase, cyclic ADP ribose hydrolase and base-exchange activities. Two of the enzymatic products, cyclic ADP-ribose (cADPR) and nicotinic acid adenine dinucleotide phosphate (NAADP), are calcium messengers in a wide variety of cells from protist, plant, and mammal to human. CD38 is a positive and negative regulator of cell activation and proliferation, depending on the cellular environment. It is involved in adhesion between human lymphocytes and endothelial cells and is involved in the metabolism of two calcium messengers, cADPR and NAADP.CD157 (also called BP-3/IF-7, BST-1 or Mo5) has ADP-ribosyl cyclase and cyclic ADP-ribose hydrolase activities. CD157 supports the growth of a pre-B cell line, DW34. Anti-CD157 mAb IF-7 has synergistic effects on anti-CD3-induced growth of T progenitor cells, and facilitates the development of [alpha][beta]TCR+ cells in foetal thymic organ culture system.
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Publication
38636518 | J:348038
   
First Author: Terao R
Year: 2024
Journal: Cell Rep
Title: LXR/CD38 activation drives cholesterol-induced macrophage senescence and neurodegeneration via NAD(+) depletion.
Pages: 114102
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Publication
37392736 | J:338301
First Author: Evrard M
Year: 2023
Journal: Immunity
Title: Single-cell protein expression profiling resolves circulating and resident memory T cell diversity across tissues and infection contexts.
Volume: 56
Issue: 7
Pages: 1664-1680.e9
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Publication
30820471 | J:278025
 
First Author: Yamamoto Y
Year: 2019
Journal: Commun Biol
Title: Vascular RAGE transports oxytocin into the brain to elicit its maternal bonding behaviour in mice.
Volume: 2
Pages: 76
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Publication
25630702 | J:217519
First Author: Hobeika E
Year: 2015
Journal: EMBO J
Title: CD19 and BAFF-R can signal to promote B-cell survival in the absence of Syk.
Volume: 34
Issue: 7
Pages: 925-39
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Publication
7819143 | J:21279
First Author: Dong C
Year: 1994
Journal: Int Immunol
Title: The murine BP-3 gene encodes a relative of the CD38/NAD glycohydrolase family.
Volume: 6
Issue: 9
Pages: 1353-60
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Publication
17003133 | J:114691
First Author: Perl A
Year: 2006
Journal: Proc Natl Acad Sci U S A
Title: Transaldolase is essential for maintenance of the mitochondrial transmembrane potential and fertility of spermatozoa.
Volume: 103
Issue: 40
Pages: 14813-8
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Publication
30169526 | J:265519
First Author: LĂĽcke K
Year: 2018
Journal: PLoS One
Title: Control of Listeria monocytogenes infection requires classical IL-6 signaling in myeloid cells.
Volume: 13
Issue: 8
Pages: e0203395
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Publication
26837762 | J:231630
First Author: Krenn PW
Year: 2016
Journal: Cancer Res
Title: ILK Induction in Lymphoid Organs by a TNFα-NF-κB-Regulated Pathway Promotes the Development of Chronic Lymphocytic Leukemia.
Volume: 76
Issue: 8
Pages: 2186-96
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Publication
30012853 | J:265470
First Author: Chen L
Year: 2018
Journal: Cancer Discov
Title: CD38-Mediated Immunosuppression as a Mechanism of Tumor Cell Escape from PD-1/PD-L1 Blockade.
Volume: 8
Issue: 9
Pages: 1156-1175
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Publication
24934597 | J:333067
 
First Author: Cortés JR
Year: 2014
Journal: J Autoimmun
Title: Maintenance of immune tolerance by Foxp3+ regulatory T cells requires CD69 expression.
Volume: 55
Pages: 51-62
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Publication
28143955 | J:241071
First Author: Laidlaw BJ
Year: 2017
Journal: J Exp Med
Title: The Eph-related tyrosine kinase ligand Ephrin-B1 marks germinal center and memory precursor B cells.
Volume: 214
Issue: 3
Pages: 639-649
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Publication
18495959 | J:142165
First Author: Spiegl N
Year: 2008
Journal: Blood
Title: Human basophils activated by mast cell-derived IL-3 express retinaldehyde dehydrogenase-II and produce the immunoregulatory mediator retinoic acid.
Volume: 112
Issue: 9
Pages: 3762-71
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Publication
24022692 | J:328702
First Author: Göthert JR
Year: 2013
Journal: Cancer Immunol Immunother
Title: Expanded CD8+ T cells of murine and human CLL are driven into a senescent KLRG1+ effector memory phenotype.
Volume: 62
Issue: 11
Pages: 1697-1709
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Publication
32572044 | J:293761
First Author: Gerasimenko M
Year: 2020
Journal: Sci Rep
Title: Nicotinamide riboside supplementation corrects deficits in oxytocin, sociability and anxiety of CD157 mutants in a mouse model of autism spectrum disorder.
Volume: 10
Issue: 1
Pages: 10035
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Publication
36689294 | J:355531
First Author: Huang K
Year: 2023
Journal: ACS Sens
Title: Base-Exchange Enabling the Visualization of SARM1 Activities in Sciatic Nerve-Injured Mice.
Volume: 8
Issue: 2
Pages: 767-773
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Publication
28783166 | J:252674
First Author: D'Abundo L
Year: 2017
Journal: Oncogene
Title: Anti-leukemic activity of microRNA-26a in a chronic lymphocytic leukemia mouse model.
Volume: 36
Issue: 47
Pages: 6617-6626
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Publication
7961800 | J:21495
First Author: Tohgo A
Year: 1994
Journal: J Biol Chem
Title: Essential cysteine residues for cyclic ADP-ribose synthesis and hydrolysis by CD38.
Volume: 269
Issue: 46
Pages: 28555-7
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Publication
7983705 | J:22259
First Author: Rochford R
Year: 1995
Journal: J Virol
Title: Differential Epstein-Barr virus gene expression in B-cell subsets recovered from lymphomas in SCID mice after transplantation of human peripheral blood lymphocytes.
Volume: 69
Issue: 1
Pages: 150-5
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Publication
8881035 | J:37620
First Author: Dong C
Year: 1996
Journal: Immunogenetics
Title: Genomic organization and chromosomal localization of the mouse Bp3 gene, a member of the CD38/ADP-ribosyl cyclase family.
Volume: 45
Issue: 1
Pages: 35-43
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Publication
10477767 | J:57587
First Author: Sun L
Year: 1999
Journal: J Cell Biol
Title: CD38/ADP-ribosyl cyclase: A new role in the regulation of osteoclastic bone resorption.
Volume: 146
Issue: 5
Pages: 1161-72
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Publication
20645413 | J:167268
First Author: Okuda H
Year: 2010
Journal: Glia
Title: Contribution of P2X7 receptors to adenosine uptake by cultured mouse astrocytes.
Volume: 58
Issue: 14
Pages: 1757-65
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Publication
39868348 | J:361609
 
First Author: Liao P
Year: 2025
Journal: J Orthop Translat
Title: Single-cell transcriptomics identifies the common perturbations of monocyte/macrophage lineage cells in inflammaging of bone marrow.
Volume: 50
Pages: 85-96
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Publication
29158362 | J:257706
First Author: Green DJ
Year: 2018
Journal: Blood
Title: CD38-bispecific antibody pretargeted radioimmunotherapy for multiple myeloma and other B-cell malignancies.
Volume: 131
Issue: 6
Pages: 611-620
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Publication
34777396 | J:327774
 
First Author: Pradhan K
Year: 2021
Journal: Front Immunol
Title: Development of Exhausted Memory Monocytes and Underlying Mechanisms.
Volume: 12
Pages: 778830
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Publication
22238321 | J:181199
First Author: Long BR
Year: 2012
Journal: J Virol
Title: Alpha interferon and HIV infection cause activation of human T cells in NSG-BLT mice.
Volume: 86
Issue: 6
Pages: 3327-36
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Publication
28278296 | J:245233
First Author: Cockrell DC
Year: 2017
Journal: PLoS One
Title: Robust growth of avirulent phase II Coxiella burnetii in bone marrow-derived murine macrophages.
Volume: 12
Issue: 3
Pages: e0173528
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Publication
26850364 | J:252275
 
First Author: Dolgacheva LP
Year: 2016
Journal: Arch Biochem Biophys
Title: Angiotensin II activates different calcium signaling pathways in adipocytes.
Volume: 593
Pages: 38-49
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Publication
34313548 | J:321684
First Author: Nabar NR
Year: 2022
Journal: Autophagy
Title: LRRK2 is required for CD38-mediated NAADP-Ca2+ signaling and the downstream activation of TFEB (transcription factor EB) in immune cells.
Volume: 18
Issue: 1
Pages: 204-222
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Publication
- | J:38102
First Author: Peters J
Year: 1996
Journal: Mouse Genome
Title: New Gene Symbols
Volume: 94
Issue: 4
Pages: 700-14
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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