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Search results 401 to 500 out of 511 for Cd3e

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Type Details Score
Publication
15514019 | J:93240
First Author: Brenner O
Year: 2004
Journal: Proc Natl Acad Sci U S A
Title: Loss of Runx3 function in leukocytes is associated with spontaneously developed colitis and gastric mucosal hyperplasia.
Volume: 101
Issue: 45
Pages: 16016-21
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Publication
28964716 | J:257520
First Author: Sardella C
Year: 2018
Journal: J Invest Dermatol
Title: Delayed Hair Follicle Morphogenesis and Hair Follicle Dystrophy in a Lipoatrophy Mouse Model of Pparg Total Deletion.
Volume: 138
Issue: 3
Pages: 500-510
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Publication
15245428 | J:91218
First Author: Sundberg JP
Year: 2004
Journal: J Invest Dermatol
Title: Adult-onset Alopecia areata is a complex polygenic trait in the C3H/HeJ mouse model.
Volume: 123
Issue: 2
Pages: 294-7
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Publication
31980640 | J:283927
First Author: Choi SY
Year: 2020
Journal: Nat Commun
Title: YAP/TAZ direct commitment and maturation of lymph node fibroblastic reticular cells.
Volume: 11
Issue: 1
Pages: 519
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Publication
23071096 | J:192856
First Author: George NM
Year: 2012
Journal: Mol Cell Biol
Title: Hippo signaling regulates pancreas development through inactivation of Yap.
Volume: 32
Issue: 24
Pages: 5116-28
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Publication
20805985 | J:164021
First Author: Bremer J
Year: 2010
Journal: PLoS One
Title: Ablation of Dicer from murine Schwann cells increases their proliferation while blocking myelination.
Volume: 5
Issue: 8
Pages: e12450
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Publication
17277142 | J:143981
First Author: Hervas-Stubbs S
Year: 2007
Journal: J Immunol
Title: Insect baculoviruses strongly potentiate adaptive immune responses by inducing type I IFN.
Volume: 178
Issue: 4
Pages: 2361-9
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Publication
29596938 | J:309497
First Author: Piao X
Year: 2019
Journal: J Allergy Clin Immunol
Title: Blockade of TNF receptor superfamily 1 (TNFR1)-dependent and TNFR1-independent cell death is crucial for normal epidermal differentiation.
Volume: 143
Issue: 1
Pages: 213-228.e10
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Publication
27653694 | J:239115
First Author: Kurbet AS
Year: 2016
Journal: Cell Rep
Title: Sterile Inflammation Enhances ECM Degradation in Integrin β1 KO Embryonic Skin.
Volume: 16
Issue: 12
Pages: 3334-3347
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Publication
26743624 | J:229471
First Author: Branchfield K
Year: 2016
Journal: Science
Title: Pulmonary neuroendocrine cells function as airway sensors to control lung immune response.
Volume: 351
Issue: 6274
Pages: 707-10
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Publication
23793062 | J:205441
First Author: Liang Y
Year: 2013
Journal: Nat Immunol
Title: The lymphoid lineage-specific actin-uncapping protein Rltpr is essential for costimulation via CD28 and the development of regulatory T cells.
Volume: 14
Issue: 8
Pages: 858-66
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Publication
29798841 | J:277787
First Author: Ikuta K
Year: 2019
Journal: Gut
Title: Nardilysin inhibits pancreatitis and suppresses pancreatic ductal adenocarcinoma initiation in mice.
Volume: 68
Issue: 5
Pages: 882-892
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Publication
1431091 | J:3170
First Author: Morse HC 3rd
Year: 1992
Journal: J Immunol
Title: Genetic nomenclature for loci controlling surface antigens of mouse hemopoietic cells.
Volume: 149
Issue: 10
Pages: 3129-34
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
- | J:73065
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
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Publication
- | J:57656
     
First Author: Lennon G
Year: 1999
Journal: Database Download
Title: WashU-HHMI Mouse EST Project
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Publication
- | J:157065
     
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
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Publication
- | J:155856
       
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Gene
key_29378 | *CD3E*
Type: gene
Organism: sheep
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Gene
key_29377 | *CD3E*
Type: gene
Organism: pig, domestic
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Publication
7937778 | J:81711
First Author: Wang B
Year: 1994
Journal: Proc Natl Acad Sci U S A
Title: A block in both early T lymphocyte and natural killer cell development in transgenic mice with high-copy numbers of the human CD3E gene.
Volume: 91
Issue: 20
Pages: 9402-6
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Strain
MGI:5705849 | B6.Cg-Cd3e<tm1Mal> Prss16<tm1.1Mal>/Cnbc
Attribute String: congenic, mutant strain, targeted mutation
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Publication
28257450 | J:248423
First Author: Buszko M
Year: 2017
Journal: PLoS One
Title: Differential depletion of total T cells and regulatory T cells and prolonged allotransplant survival in CD3Ɛ humanized mice treated with polyclonal anti human thymocyte globulin.
Volume: 12
Issue: 3
Pages: e0173088
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Allele
Cd3e<em5Smoc> | MGI:7288824
Name: CD3 antigen, epsilon polypeptide; endonuclease-mediated mutation 5, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Protein Coding Gene
MGI:1917583 | Polr1g
Type: protein_coding_gene
Organism: mouse, laboratory
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DO Term
DOID:0111971 | immunodeficiency 18
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Strain
MGI:6428364 | C57BL/6JSmoc-Cd3e<em5Smoc>/Smoc
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
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Allele
Cd3e<em4(CD3E)Smoc> | MGI:7288823
Name: CD3 antigen, epsilon polypeptide; endonuclease-mediated mutation 4, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Humanized sequence, Inserted expressed sequence
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Allele
Cd3e<em1Smoc> | MGI:7288820
Name: CD3 antigen, epsilon polypeptide; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
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Allele
Cd3e<em2(CD3E)Smoc> | MGI:7288821
Name: CD3 antigen, epsilon polypeptide; endonuclease-mediated mutation 2, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Humanized sequence, Inserted expressed sequence
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Strain
MGI:6770637 | C57BL/6JSmoc-Cd3e<em4(CD3E)Smoc>/Smoc
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Allele
Cd3d<tm1Kap> | MGI:2180760
Name: CD3 antigen, delta polypeptide; targeted mutation 1, Dietmar J Kappes
Allele Type: Targeted
Attribute String: Null/knockout
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Allele
Tg(CD3E)#Alat | MGI:6098724
Name: transgene insertion, Alan Tunnacliffe
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
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Allele
Tg(CD3E)16Alat | MGI:6098738
Name: transgene insertion 16, Alan Tunnacliffe
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
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Allele
Tg(CD3E)21Alat | MGI:6098739
Name: transgene insertion 21, Alan Tunnacliffe
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
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Allele
Tg(CD3E)22Alat | MGI:6098740
Name: transgene insertion 22, Alan Tunnacliffe
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
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Allele
Tg(CD3E)31Alat | MGI:6098741
Name: transgene insertion 31, Alan Tunnacliffe
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
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Allele
Tg(CD3E)41Alat | MGI:6098742
Name: transgene insertion 41, Alan Tunnacliffe
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
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Allele
Cd3e<tm1.1(CD3E)Bms> | MGI:7398576
Name: CD3 antigen, epsilon polypeptide; targeted mutation 1.1, Bristol Myers Squibb
Allele Type: Targeted
Attribute String: Humanized sequence
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Strain
MGI:3716142 | C57BL/6-Cd3d<tm1Kap>
Attribute String: coisogenic, mutant strain, targeted mutation
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Publication
9135151 | J:39925
First Author: Dave VP
Year: 1997
Journal: EMBO J
Title: CD3 delta deficiency arrests development of the alpha beta but not the gamma delta T cell lineage.
Volume: 16
Issue: 6
Pages: 1360-70
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Allele
Del(9Cd3g-Cd3d)1Cpt | MGI:2180768
Name: deletion, Chr 9, Cox Terhorst 1
Allele Type: Targeted
Attribute String: Null/knockout
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Publication
9763617 | J:76991
First Author: Wang B
Year: 1998
Journal: J Exp Med
Title: Essential and partially overlapping role of CD3gamma and CD3delta for development of alphabeta and gammadelta T lymphocytes.
Volume: 188
Issue: 7
Pages: 1375-80
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Publication
16888097 | J:140444
First Author: Fernández-Malavé E
Year: 2006
Journal: Blood
Title: Overlapping functions of human CD3delta and mouse CD3gamma in alphabeta T-cell development revealed in a humanized CD3gamma-mouse.
Volume: 108
Issue: 10
Pages: 3420-7
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Allele
Cd3e<tm1.1Lov> | MGI:2384123
Name: CD3 antigen, epsilon polypeptide; targeted mutation 1.1, Paul E Love
Allele Type: Targeted
Attribute String: Null/knockout
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Publication
21289272 | J:171005
First Author: Kuhn C
Year: 2011
Journal: Sci Transl Med
Title: Human CD3 transgenic mice: preclinical testing of antibodies promoting immune tolerance.
Volume: 3
Issue: 68
Pages: 68ra10
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Publication
29030662 | J:257622
First Author: Besançon A
Year: 2018
Journal: Diabetologia
Title: Oral histone deacetylase inhibitor synergises with T cell targeted immunotherapy to preserve beta cell metabolic function and induce stable remission of new-onset autoimmune diabetes in NOD mice.
Volume: 61
Issue: 2
Pages: 389-398
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Strain
MGI:6355102 | C57BL/6JSmoc-Pdcd1<em1(PDCD1)Smoc> Cd3e<em2(CD3E)Smoc>/Smoc
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
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Allele
Cd3e<tm1.1Arte> | MGI:6791371
Name: CD3 antigen, epsilon polypeptide; targeted mutation 1.1, TaconicArtemis
Allele Type: Targeted
Attribute String: Humanized sequence
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Strain
MGI:7718297 | C57BL/6JSmoc-Tnfrsf9<tm2(TNFRSF9)Smoc> Cd3e<em4(CD3E)Smoc>/Smoc
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Genotype
Genotype
Symbol: Cd3d/Cd3d
Background: C57BL/6-Cd3d
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Del(9Cd3g-Cd3d)1Cpt/Del(9Cd3g-Cd3d)1Cpt
Background: involves: 129S4/SvJae * C57BL/6
Zygosity: hm
Has Mutant Allele: true
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Allele
Cd3e<tm1Lov> | MGI:2384120
Name: CD3 antigen, epsilon polypeptide; targeted mutation 1, Paul E Love
Allele Type: Targeted
Attribute String: Modified regulatory region, Null/knockout
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Protein Domain
IPR035559 | Nck2_SH3_1
Type: Domain
Description: This entry represent the first SH3 domain of Nck2. It binds the PxxDY sequence in the CD3e cytoplasmic tail; this binding inhibits phosphorylation by Src kinases, resulting in the downregulation of TCR surface expression []. Nck2 (also known as Grb4) is a member of the Nck family. It plays a crucial role in connecting signaling pathways of tyrosine kinase receptors and important effectors in actin dynamics and cytoskeletal remodeling []. It binds neuronal signaling proteins such as ephrinB []. Cytoplasmic proteins Nck are non-enzymatic adaptor proteins composed of three SH3 (Src homology 3) domains and a C-terminal SH2 domain []. They regulate actin cytoskeleton dynamics by linking proline-rich effector molecules to protein tyrosine kinases and phosphorylated signaling intermediates []. They function downstream of the PDGFbeta receptor and are involved in Rho GTPase signaling and actin dynamics []. They associate with tyrosine-phosphorylated growth factor receptors or their cellular substrates [, ]. There are two vertebrate Nck proteins, Nck1 and Nck2.
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Publication
18555270 | -
First Author: Takeuchi K
Year: 2008
Journal: J Mol Biol
Title: Structural and functional evidence that Nck interaction with CD3epsilon regulates T-cell receptor activity.
Volume: 380
Issue: 4
Pages: 704-16
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Publication
12444133 | J:112127
First Author: D'Oro U
Year: 2002
Journal: J Immunol
Title: Regulation of constitutive TCR internalization by the zeta-chain.
Volume: 169
Issue: 11
Pages: 6269-78
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Publication
27899442 | J:237494
First Author: Hayakawa K
Year: 2016
Journal: J Exp Med
Title: Early generated B1 B cells with restricted BCRs become chronic lymphocytic leukemia with continued c-Myc and low Bmf expression.
Volume: 213
Issue: 13
Pages: 3007-3024
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Strain
MGI:2174169 | B6;129-Cd3e<tm1Lov>/J
Attribute String: targeted mutation, mutant stock
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Publication
2484963 | J:249821
First Author: Tunnacliffe A
Year: 1989
Journal: Int Immunol
Title: The majority of human CD3 epitopes are conferred by the epsilon chain.
Volume: 1
Issue: 5
Pages: 546-50
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Genotype
Genotype
Symbol: Cd3e/Cd3e
Background: Not Specified
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Cd3e/Cd3e
Background: involves: 129S1/Sv * 129X1/SvJ
Zygosity: hm
Has Mutant Allele: true
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Publication
15546002 | J:94425
First Author: de Saint Basile G
Year: 2004
Journal: J Clin Invest
Title: Severe combined immunodeficiency caused by deficiency in either the delta or the epsilon subunit of CD3.
Volume: 114
Issue: 10
Pages: 1512-7
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HT Experiment
GSE48048 | Gene expression profiling normal murine myeloid cells and myeloid leukemia cells induced by CNTRL-FGFR1
Series Id: E-GEOD-48048
Experiment Type: RNA-Seq
Study Type: Baseline
Source: GEO
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Publication
27043412 | J:259151
First Author: Muñoz-Ruiz M
Year: 2016
Journal: Nat Immunol
Title: TCR signal strength controls thymic differentiation of discrete proinflammatory γδ T cell subsets.
Volume: 17
Issue: 6
Pages: 721-727
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Genotype
Genotype
Symbol: Cd3e/Cd3e Trdc/Trdc
Background: involves: C57BL/6
Zygosity: cx
Has Mutant Allele: true
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Protein Domain
IPR035562 | Nck1_SH3_1
Type: Domain
Description: This entry represent the first SH3 domain of Nck1. The first SH3 domain of Nck binds the PxxDY sequence in the CD3e cytoplasmic tail; this binding inhibits phosphorylation by Src kinases, resulting in the downregulation of TCR surface expression [].Nck1 (also called Nck-alpha) plays a crucial role in connecting signaling pathways of tyrosine kinase receptors and important effectors in actin dynamics and cytoskeletal remodeling []. It binds and activates RasGAP, resulting in the downregulation of Ras []. It is also involved in the signaling of endothilin-mediated inhibition of cell migration [].Cytoplasmic proteins Nck are non-enzymatic adaptor proteins composed of three SH3 (Src homology 3) domains and a C-terminal SH2 domain []. They regulate actin cytoskeleton dynamics by linking proline-rich effector molecules to protein tyrosine kinases and phosphorylated signaling intermediates []. They function downstream of the PDGFbeta receptor and are involved in Rho GTPase signaling and actin dynamics []. They associate with tyrosine-phosphorylated growth factor receptors or their cellular substrates [, ]. There are two vertebrate Nck proteins, Nck1 and Nck2.
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Publication
- | J:15885
 
First Author: Womack JE
Year: 1991
Journal: Cytogenet Cell Genet
Title: Assignment of 47 additional comparative anchor loci to the bovine synteny map
Volume: 58
Pages: 2132 (Abstr.)
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Publication
17923503 | J:126111
First Author: Siegers GM
Year: 2007
Journal: J Exp Med
Title: Different composition of the human and the mouse gammadelta T cell receptor explains different phenotypes of CD3gamma and CD3delta immunodeficiencies.
Volume: 204
Issue: 11
Pages: 2537-44
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Publication
20660709 | J:163269
First Author: Kim ST
Year: 2010
Journal: J Immunol
Title: Distinctive CD3 heterodimeric ectodomain topologies maximize antigen-triggered activation of alpha beta T cell receptors.
Volume: 185
Issue: 5
Pages: 2951-9
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Publication
19182796 | J:150550
First Author: Xu NJ
Year: 2009
Journal: Nat Neurosci
Title: Ephrin-B3 reverse signaling through Grb4 and cytoskeletal regulators mediates axon pruning.
Volume: 12
Issue: 3
Pages: 268-76
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Publication
1824636 | J:172562
First Author: de la Hera A
Year: 1991
Journal: J Exp Med
Title: Structure of the T cell antigen receptor (TCR): two CD3 epsilon subunits in a functional TCR/CD3 complex.
Volume: 173
Issue: 1
Pages: 7-17
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Publication
21664272 | -
First Author: Ger M
Year: 2011
Journal: Cell Signal
Title: Adaptor protein Nck1 interacts with p120 Ras GTPase-activating protein and regulates its activity.
Volume: 23
Issue: 10
Pages: 1651-8
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Publication
15187089 | -
First Author: Miyamoto Y
Year: 2004
Journal: J Biol Chem
Title: The adaptor protein Nck1 mediates endothelin A receptor-regulated cell migration through the Cdc42-dependent c-Jun N-terminal kinase pathway.
Volume: 279
Issue: 33
Pages: 34336-42
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Publication
20971703 | -
First Author: Oser M
Year: 2010
Journal: J Cell Sci
Title: Specific tyrosine phosphorylation sites on cortactin regulate Nck1-dependent actin polymerization in invadopodia.
Volume: 123
Issue: Pt 21
Pages: 3662-73
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Publication
9344857 | -
First Author: Matuoka K
Year: 1997
Journal: Biochem Biophys Res Commun
Title: A novel ligand for an SH3 domain of the adaptor protein Nck bears an SH2 domain and nuclear signaling motifs.
Volume: 239
Issue: 2
Pages: 488-92
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Publication
11240126 | -
First Author: Tu Y
Year: 2001
Journal: FEBS Lett
Title: Identification and kinetic analysis of the interaction between Nck-2 and DOCK180.
Volume: 491
Issue: 3
Pages: 193-9
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Publication
12034353 | -
First Author: Buday L
Year: 2002
Journal: Cell Signal
Title: The Nck family of adapter proteins: regulators of actin cytoskeleton.
Volume: 14
Issue: 9
Pages: 723-31
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Publication
18765673 | J:142544
First Author: Ruusala A
Year: 2008
Journal: J Biol Chem
Title: Nck adapters are involved in the formation of dorsal ruffles, cell migration, and Rho signaling downstream of the platelet-derived growth factor beta receptor.
Volume: 283
Issue: 44
Pages: 30034-44
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