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Search results 401 to 500 out of 537 for Cd55

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Type Details Score
GXD Expression
GXD Expression
   
Probe: MGI:4423326
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:2826026
Stage: TS26
Assay Id: MGI:5540608
Age: embryonic day 17.5
Image: GUDMAP:14844
Specimen Label: GUDMAP:14844
Detected: false
Specimen Num: 1
•
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•
GXD Expression
GXD Expression
   
Probe: MGI:4423326
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:2826028
Stage: TS28
Assay Id: MGI:5540608
Age: postnatal day 84
Image: GUDMAP:14845
Specimen Label: GUDMAP:14845
Detected: false
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4423326
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2796726
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:5540608
Age: embryonic day 17.5
Image: GUDMAP:14844
Specimen Label: GUDMAP:14844
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:4423326
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:2777626
Stage: TS26
Assay Id: MGI:5540608
Age: embryonic day 17.5
Image: GUDMAP:14844
Specimen Label: GUDMAP:14844
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4423326
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1679723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824225
Age: embryonic day 14.5
Image: euxassay_009544_04
Specimen Label: euxassay_009544_04
Detected: true
Specimen Num: 4
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•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4423326
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1679723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824225
Age: embryonic day 14.5
Image: euxassay_009544_05
Specimen Label: euxassay_009544_05
Detected: true
Specimen Num: 5
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4423326
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1679723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824225
Age: embryonic day 14.5
Image: euxassay_009544_06
Specimen Label: euxassay_009544_06
Detected: true
Specimen Num: 6
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4423326
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1679723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824225
Age: embryonic day 14.5
Image: euxassay_009544_07
Specimen Label: euxassay_009544_07
Detected: true
Specimen Num: 7
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4423326
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1679723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824225
Age: embryonic day 14.5
Image: euxassay_009544_08
Specimen Label: euxassay_009544_08
Detected: true
Specimen Num: 8
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4423326
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1679723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824225
Age: embryonic day 14.5
Image: euxassay_009544_09
Specimen Label: euxassay_009544_09
Detected: true
Specimen Num: 9
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4423326
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1679723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824225
Age: embryonic day 14.5
Image: euxassay_009544_19
Specimen Label: euxassay_009544_19
Detected: true
Specimen Num: 19
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4423326
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1679723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824225
Age: embryonic day 14.5
Image: euxassay_009544_20
Specimen Label: euxassay_009544_20
Detected: true
Specimen Num: 20
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•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4423326
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1679723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824225
Age: embryonic day 14.5
Image: euxassay_009544_21
Specimen Label: euxassay_009544_21
Detected: true
Specimen Num: 21
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4423326
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1679723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824225
Age: embryonic day 14.5
Image: euxassay_009544_22
Specimen Label: euxassay_009544_22
Detected: true
Specimen Num: 22
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4423326
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1679723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824225
Age: embryonic day 14.5
Image: euxassay_009544_23
Specimen Label: euxassay_009544_23
Detected: true
Specimen Num: 23
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:4423326
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:2814226
Stage: TS26
Assay Id: MGI:5540608
Age: embryonic day 17.5
Image: GUDMAP:14844
Specimen Label: GUDMAP:14844
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:4423326
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:2814228
Stage: TS28
Assay Id: MGI:5540608
Age: postnatal day 84
Image: GUDMAP:14845
Specimen Label: GUDMAP:14845
Detected: false
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:4423326
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1897626
Stage: TS26
Assay Id: MGI:5540608
Age: embryonic day 17.5
Image: GUDMAP:14844
Specimen Label: GUDMAP:14844
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:4423326
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:1897628
Stage: TS28
Assay Id: MGI:5540608
Age: postnatal day 84
Image: GUDMAP:14845
Specimen Label: GUDMAP:14845
Detected: false
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:4423326
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:2969128
Stage: TS28
Assay Id: MGI:5540608
Age: postnatal day 84
Image: GUDMAP:14845
Specimen Label: GUDMAP:14845
Detected: false
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4423326
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2823926
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:5540608
Age: embryonic day 17.5
Image: GUDMAP:14844
Specimen Label: GUDMAP:14844
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4423326
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1702423
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824225
Age: embryonic day 14.5
Image: euxassay_009544_01
Specimen Label: euxassay_009544_01
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4423326
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1702423
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824225
Age: embryonic day 14.5
Image: euxassay_009544_02
Specimen Label: euxassay_009544_02
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4423326
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1702423
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824225
Age: embryonic day 14.5
Image: euxassay_009544_03
Specimen Label: euxassay_009544_03
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4423326
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1702423
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824225
Age: embryonic day 14.5
Image: euxassay_009544_04
Specimen Label: euxassay_009544_04
Detected: true
Specimen Num: 4
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4423326
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1702423
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824225
Age: embryonic day 14.5
Image: euxassay_009544_05
Specimen Label: euxassay_009544_05
Detected: true
Specimen Num: 5
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4423326
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1702423
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824225
Age: embryonic day 14.5
Image: euxassay_009544_06
Specimen Label: euxassay_009544_06
Detected: true
Specimen Num: 6
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4423326
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1702423
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824225
Age: embryonic day 14.5
Image: euxassay_009544_07
Specimen Label: euxassay_009544_07
Detected: true
Specimen Num: 7
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4423326
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1702423
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824225
Age: embryonic day 14.5
Image: euxassay_009544_08
Specimen Label: euxassay_009544_08
Detected: true
Specimen Num: 8
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4423326
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1702423
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824225
Age: embryonic day 14.5
Image: euxassay_009544_09
Specimen Label: euxassay_009544_09
Detected: true
Specimen Num: 9
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:4423326
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:2777826
Stage: TS26
Assay Id: MGI:5540608
Age: embryonic day 17.5
Image: GUDMAP:14844
Specimen Label: GUDMAP:14844
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4423326
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1702123
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824225
Age: embryonic day 14.5
Image: euxassay_009544_08
Specimen Label: euxassay_009544_08
Detected: true
Specimen Num: 8
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4423326
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1702123
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824225
Age: embryonic day 14.5
Image: euxassay_009544_09
Specimen Label: euxassay_009544_09
Detected: true
Specimen Num: 9
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4423326
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1702123
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824225
Age: embryonic day 14.5
Image: euxassay_009544_10
Specimen Label: euxassay_009544_10
Detected: true
Specimen Num: 10
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:4423326
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:2797326
Stage: TS26
Assay Id: MGI:5540608
Age: embryonic day 17.5
Image: GUDMAP:14844
Specimen Label: GUDMAP:14844
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4423326
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2823626
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:5540608
Age: embryonic day 17.5
Image: GUDMAP:14844
Specimen Label: GUDMAP:14844
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:4423326
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:2826626
Stage: TS26
Assay Id: MGI:5540608
Age: embryonic day 17.5
Image: GUDMAP:14844
Specimen Label: GUDMAP:14844
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:4423326
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:2826628
Stage: TS28
Assay Id: MGI:5540608
Age: postnatal day 84
Image: GUDMAP:14845
Specimen Label: GUDMAP:14845
Detected: false
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:4423326
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:2772126
Stage: TS26
Assay Id: MGI:5540608
Age: embryonic day 17.5
Image: GUDMAP:14844
Specimen Label: GUDMAP:14844
Detected: false
Specimen Num: 1
•
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•
Allele
Cd55<tm1Mme> | MGI:2383980
Name: CD55 molecule, decay accelerating factor for complement; targeted mutation 1, M Edward Medof
Allele Type: Targeted
Attribute String: Null/knockout
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Allele
Cd55<tm1Song> | MGI:2387405
Name: CD55 molecule, decay accelerating factor for complement; targeted mutation 1, Wen-Chao Song
Allele Type: Targeted
Attribute String: Null/knockout
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Allele
Cd55<tm1a(EUCOMM)Hmgu> | MGI:4458663
Name: CD55 molecule, decay accelerating factor for complement; targeted mutation 1a, Helmholtz Zentrum Muenchen GmbH
Allele Type: Targeted
Attribute String: Conditional ready, Null/knockout, Reporter
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Allele
Cd55<tm1e(EUCOMM)Hmgu> | MGI:4458795
Name: CD55 molecule, decay accelerating factor for complement; targeted mutation 1e, Helmholtz Zentrum Muenchen GmbH
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
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Allele
Cd55<tm1b(EUCOMM)Hmgu> | MGI:5692553
Name: CD55 molecule, decay accelerating factor for complement; targeted mutation 1b, Helmholtz Zentrum Muenchen GmbH
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
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Allele
Cd55<tm1c(EUCOMM)Hmgu> | MGI:6502875
Name: CD55 molecule, decay accelerating factor for complement; targeted mutation 1c, Helmholtz Zentrum Muenchen GmbH
Allele Type: Targeted
Attribute String: Conditional ready
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Allele
Cd55<em1Gpt> | MGI:7296603
Name: CD55 molecule, decay accelerating factor for complement; endonuclease-mediated mutation 1, GemPharmatech Co., Ltd
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
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Allele
Cd55<em2Gpt> | MGI:7296604
Name: CD55 molecule, decay accelerating factor for complement; endonuclease-mediated mutation 2, GemPharmatech Co., Ltd
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Allele
Cd55b<em1Gpt> | MGI:7296605
Name: CD55 molecule, decay accelerating factor for complement B; endonuclease-mediated mutation 1, GemPharmatech Co., Ltd
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
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Allele
Cd55<em2Cya> | MGI:7792593
Name: CD55 molecule, decay accelerating factor for complement; endonuclease-mediated mutation 2, Cyagen Biosciences
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
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Strain
MGI:7258450 | B6.129S6-Cd55<tm1Song>/J
Attribute String: congenic, mutant strain, targeted mutation
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Strain
MGI:5299147 | B6.129S6-Cd55<tm1Song>
Attribute String: congenic, mutant strain, targeted mutation
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Strain
MGI:4429536 | C.129S6(B6)-Cd55<tm1Song>/Mmmh
Attribute String: congenic, mutant strain, targeted mutation
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Strain
MGI:6143247 | C57BL/6N-Cd55<tm1a(EUCOMM)Hmgu> A<tm1Brd>/a/BayMmucd
Attribute String: mutant strain, coisogenic, targeted mutation
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Allele
Cd55b<tm1e(KOMP)Wtsi> | MGI:4868031
Name: CD55 molecule, decay accelerating factor for complement B; targeted mutation 1e, Wellcome Trust Sanger Institute
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
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Allele
Cd55b<tm1a(KOMP)Wtsi> | MGI:4868034
Name: CD55 molecule, decay accelerating factor for complement B; targeted mutation 1a, Wellcome Trust Sanger Institute
Allele Type: Targeted
Attribute String: Conditional ready, Null/knockout, Reporter
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Strain
MGI:5700735 | C57BL/6N-Cd55b<tm1a(KOMP)Wtsi>/Wtsi
Attribute String: coisogenic, targeted mutation
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Allele
Cd55b<tm1(NCOM)Mfgc> | MGI:4880574
Name: CD55 molecule, decay accelerating factor for complement B; targeted mutation 1, Mammalian Functional Genomics Centre
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
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Strain
MGI:6678417 | C57BL/6N-Cd55<tm1b(EUCOMM)Hmgu>/BayMmucd
Attribute String: coisogenic, targeted mutation
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Strain
MGI:6767316 | C57BL/6JGpt-Cd55b<em1Gpt>/Gpt
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
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Strain
MGI:7839213 | C57BL/6JCya-Cd55<em2Cya>/Cya
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Genotype
Genotype
Symbol: Cd55/Cd55
Background: involves: 129S6/SvEvTac * C57BL/6
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Cd55/Cd55
Background: involves: 129P2/OlaHsd * C57BL/6
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Cd55/Cd55
Background: involves: 129S6/SvEvTac
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Cd55/Cd55
Background: B6.129S6-Cd55
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Cd55b/Cd55b
Background: C57BL/6N-Cd55b/Wtsi
Zygosity: hm
Has Mutant Allele: true
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Strain
MGI:5299148 | B6.129-Cd55<tm1Song> Cd59a<tm1Bpm>
Attribute String: targeted mutation, mutant strain, congenic
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Genotype
Genotype
Symbol: Cd59a/Cd59a Cd55/Cd55
Background: involves: 129S6/SvEvTac * C57BL/6
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Cd55/Cd55 Cd59a/Cd59a
Background: B6.129-Cd55 Cd59a
Zygosity: cx
Has Mutant Allele: true
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Strain
MGI:6343951 | C57BL/6N-A<tm1Brd> Cd55b<tm1a(KOMP)Wtsi>/Mmucd
Attribute String: mutant strain, coisogenic, targeted mutation
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Strain
MGI:5557366 | C57BL/6N-A<tm1Brd> Cd55b<tm1a(KOMP)Wtsi>/WtsiH
Attribute String: mutant strain, targeted mutation, coisogenic
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Genotype
Genotype
Symbol: Cd55/Cd55<+>
Background: C57BL/6N-Cd55/BayMmucd
Zygosity: ht
Has Mutant Allele: true
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Publication
17287827 | J:121574
First Author: Aly M
Year: 2007
Journal: Genes Immun
Title: Complex genetic control of host susceptibility to coxsackievirus B3-induced myocarditis.
Volume: 8
Issue: 3
Pages: 193-204
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Allele
Gt(ROSA)26Sor<em1(CAG-Cd55*)Hgr> | MGI:7277810
Name: gene trap ROSA 26, Philippe Soriano; endonuclease-mediated mutation 1, Peter Heeger
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, Inserted expressed sequence
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Genotype
Genotype
Symbol: C3/C3 Cd55/Cd55 Cr1l/Cr1l
Background: involves: 129/Sv * 129S6/SvEvTac * 129X1/SvJ
Zygosity: cx
Has Mutant Allele: true
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Strain
MGI:7277811 | B6.Cg-Gt(ROSA)26Sor<em1(CAG-Cd55*)Hgr>/J
Attribute String: congenic, endonuclease-mediated mutation, mutant strain
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Genotype
Genotype
Symbol: C3/C3 Cd55/Cd55 Cr1l/Cr1l Vsig4/Vsig4
Background: involves: 129/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6N
Zygosity: cx
Has Mutant Allele: true
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Publication
14647991 | J:87940
First Author: Kwakkenbos MJ
Year: 2004
Journal: Immunogenetics
Title: The EGF-TM7 family: a postgenomic view.
Volume: 55
Issue: 10
Pages: 655-66
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Publication
16237120 | J:119362
First Author: Wenzel K
Year: 2005
Journal: J Immunol
Title: Increased susceptibility to complement attack due to down-regulation of decay-accelerating factor/CD55 in dysferlin-deficient muscular dystrophy.
Volume: 175
Issue: 9
Pages: 6219-25
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Publication
17597212 | J:125394
First Author: Donev RM
Year: 2008
Journal: Mol Immunol
Title: The mouse complement regulator CD59b is significantly expressed only in testis and plays roles in sperm acrosome activation and motility.
Volume: 45
Issue: 2
Pages: 534-42
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Publication
10744645 | J:61692
First Author: Hamann J
Year: 2000
Journal: Int Immunol
Title: Molecular cloning and characterization of mouse CD97.
Volume: 12
Issue: 4
Pages: 439-48
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Publication
35167491 | J:327263
 
First Author: Tsao LC
Year: 2022
Journal: JCI Insight
Title: Trastuzumab/pertuzumab combination therapy stimulates antitumor responses through complement-dependent cytotoxicity and phagocytosis.
Volume: 7
Issue: 6
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Publication
30174588 | J:281933
 
First Author: Inafuku S
Year: 2018
Journal: Front Mol Neurosci
Title: The Alternative Complement System Mediates Cell Death in Retinal Ischemia Reperfusion Injury.
Volume: 11
Pages: 278
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Publication
26631482 | J:230898
First Author: Kim C
Year: 2016
Journal: FASEB J
Title: The alternative complement pathway aids in vascular regression during the early stages of a murine model of proliferative retinopathy.
Volume: 30
Issue: 3
Pages: 1300-5
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Publication
24668752 | J:216533
First Author: Sweigard JH
Year: 2014
Journal: FASEB J
Title: The alternative complement pathway regulates pathological angiogenesis in the retina.
Volume: 28
Issue: 7
Pages: 3171-82
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Publication
12692150 | J:83792
First Author: Alfieri JA
Year: 2003
Journal: J Cell Sci
Title: Infertility in female mice with an oocyte-specific knockout of GPI-anchored proteins.
Volume: 116
Issue: Pt 11
Pages: 2149-55
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Publication
21651971 | J:186744
First Author: Markovich D
Year: 2011
Journal: Exp Gerontol
Title: Increased lifespan in hyposulfatemic NaS1 null mice.
Volume: 46
Issue: 10
Pages: 833-5
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Publication
37925507 | J:342337
First Author: Han M
Year: 2023
Journal: Nat Commun
Title: IL-21R-STAT3 signalling initiates a differentiation program in uterine tissue-resident NK cells to support pregnancy.
Volume: 14
Issue: 1
Pages: 7109
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Publication
21252115 | J:170610
First Author: Hu W
Year: 2011
Journal: Cancer Res
Title: Human CD59 inhibitor sensitizes rituximab-resistant lymphoma cells to complement-mediated cytolysis.
Volume: 71
Issue: 6
Pages: 2298-307
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Publication
15341509 | J:127678
First Author: Knight KR
Year: 2005
Journal: Clin Sci (Lond)
Title: Transgenic expression of human complement regulators reduces skeletal muscle ischaemia/reperfusion injury in mice.
Volume: 108
Issue: 1
Pages: 47-53
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Publication
32814838 | J:303977
First Author: Zhang L
Year: 2021
Journal: Leukemia
Title: Reduced red blood cell surface level of Factor H as a mechanism underlying paroxysmal nocturnal hemoglobinuria.
Volume: 35
Issue: 4
Pages: 1176-1187
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Publication
26163592 | J:315567
First Author: Hsu FC
Year: 2015
Journal: J Immunol
Title: Histone Deacetylase 3 Is Required for T Cell Maturation.
Volume: 195
Issue: 4
Pages: 1578-90
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Protein Domain
IPR018363 | CD59_antigen_CS
Type: Conserved_site
Description: CD59 (also called 1F-5Ag, H19, HRF20, MACIF, MIRL, P-18 or protectin) inhibits formation of membrane attack complex (MAC), thus protecting cells from complement mediated lysis. It has a signalling role, as a GPI-anchored molecule, in T cell activation and appears to have some role in cell adhesion through CD2 (controversial). CD59 associates with C9, inhibiting incorporation into C5b-8 preventing terminal steps in polymerisation of the (MAC) in plasma membranes. Genetic defects in GPI-anchor attachment that cause a reduction or loss of both CD59 and CD55 on erythrocytes produce the symptoms of the disease paroxysmal nocturnal haemoglobinuria (PNH). A variety of GPI-linked cell-surface glycoproteins are composed of one or more copies of a conserved domain of about 100 amino-acid residues [], []. Among these proteins, U-PAR contains three tandem copies of the domain, while all the others are made up of a single domain.As shown in the following schematic, this conserved domain contains 10 cysteine residues involved in five disulphide bonds - in U-PAR, the first copy of the domain lacks the fourth disulphide bond.+------+ +------------------------+ +---+| | | | | |xCxxCxxxxxxCxxxxxCxxxxxCxxxxxxxxxxxxxxxxxxCxxxxCxxxxxxxxxxxxxxCCxxxCxxxxxxxx| | | |+---------------------+ +--------------+'C': conserved cysteine involved in a disulphide bond.
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Publication
28594911 | J:278478
First Author: Yan Q
Year: 2017
Journal: PLoS One
Title: Candidate genes on murine chromosome 8 are associated with susceptibility to Staphylococcus aureus infection in mice and are involved with Staphylococcus aureus septicemia in humans.
Volume: 12
Issue: 6
Pages: e0179033
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Protein
A0A087WPW7
Organism: Mus musculus/domesticus
Length: 78  
Fragment?: true
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Protein
A0A087WNV7
Organism: Mus musculus/domesticus
Length: 123  
Fragment?: false
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Publication
1850423 | -
First Author: Behrendt N
Year: 1991
Journal: J Biol Chem
Title: The ligand-binding domain of the cell surface receptor for urokinase-type plasminogen activator.
Volume: 266
Issue: 12
Pages: 7842-7
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Publication
8394346 | -
First Author: Ploug M
Year: 1993
Journal: J Biol Chem
Title: Localization of the disulfide bonds in the NH2-terminal domain of the cellular receptor for human urokinase-type plasminogen activator. A domain structure belonging to a novel superfamily of glycolipid-anchored membrane proteins.
Volume: 268
Issue: 23
Pages: 17539-46
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Protein
Q9D1N2
Organism: Mus musculus/domesticus
Length: 228  
Fragment?: false
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Protein
Q9WU67
Organism: Mus musculus/domesticus
Length: 134  
Fragment?: false
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Protein
P05533
Organism: Mus musculus/domesticus
Length: 134  
Fragment?: false
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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