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Search results 401 to 500 out of 841 for Cd80

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Type Details Score
Allele
Cd80<Gt(42v-342)Yais> | MGI:4831529
 
Name: CD80 antigen; gene trap 42v-342, Yasumasa Ishida
Allele Type: Gene trapped
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Allele
Cd80<em1Okat> | MGI:6356535
Name: CD80 antigen; endonuclease-mediated mutation 1, Taku Okazaki
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Allele
Cd80<em2Okat> | MGI:6356537
 
Name: CD80 antigen; endonuclease-mediated mutation 2, Taku Okazaki
Allele Type: Endonuclease-mediated
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Allele
Cd80<em1Cya> | MGI:7431527
Name: CD80 antigen; endonuclease-mediated mutation 1, Cyagen Biosciences
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
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Allele
Cd80<em2Cya> | MGI:7582870
Name: CD80 antigen; endonuclease-mediated mutation 2, Cyagen Biosciences
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Publication
10583602 | -
First Author: Vandenborre K
Year: 1999
Journal: Immunology
Title: Interaction of CTLA-4 (CD152) with CD80 or CD86 inhibits human T-cell activation.
Volume: 98
Issue: 3
Pages: 413-21
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Strain
MGI:3584530 | B6.Cg-H2<g7> Tg(Ins2-CD80)3B7Flv/LwnJ
Attribute String: congenic, mutant strain, transgenic, major histocompatibility congenic
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Publication
16078275 | J:113486
First Author: Skak K
Year: 2005
Journal: Eur J Immunol
Title: Preservation of beta-cell function during immune-mediated, B7-1-dependent alpha-cell destruction.
Volume: 35
Issue: 9
Pages: 2583-90
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Publication
17947667 | J:138692
First Author: Thomas IJ
Year: 2007
Journal: J Immunol
Title: CD86 has sustained costimulatory effects on CD8 T cells.
Volume: 179
Issue: 9
Pages: 5936-46
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Allele
Cd80<tm1Shr> | MGI:1861804
Name: CD80 antigen; targeted mutation 1, Arlene H Sharpe
Allele Type: Targeted
Attribute String: Null/knockout
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Allele
Cd80<Gt(PST5055)Mfgc> | MGI:3861573
 
Name: CD80 antigen; gene trap PST5055, Mammalian Functional Genomics Centre
Allele Type: Gene trapped
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Strain
MGI:6440202 | B6;129S5-Cd80<Gt(OST275298)Lex>/Tac
Attribute String: mutant stock, gene trap
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Allele
Cd80<Gt(501B6)Cmhd> | MGI:4957288
 
Name: CD80 antigen; gene trap 501B6, Centre for Modeling Human Disease
Allele Type: Gene trapped
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Allele
Cd80<Gt(329B3)Cmhd> | MGI:4966619
 
Name: CD80 antigen; gene trap 329B3, Centre for Modeling Human Disease
Allele Type: Gene trapped
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Allele
Cd80<tm1a(EUCOMM)Hmgu> | MGI:5472658
Name: CD80 antigen; targeted mutation 1a, Helmholtz Zentrum Muenchen GmbH
Allele Type: Targeted
Attribute String: Conditional ready, Null/knockout, Reporter
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Allele
Cd80<tm1e(EUCOMM)Hmgu> | MGI:5497294
Name: CD80 antigen; targeted mutation 1e, Helmholtz Zentrum Muenchen GmbH
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
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Strain
MGI:7730856 | C57BL/6JCya-Cd80<em1Cya>/Cya
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Allele
Cd80<em14Gpt> | MGI:7296622
Name: CD80 antigen; endonuclease-mediated mutation 14, GemPharmatech Co., Ltd
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Allele
Cd80<em1Gpt> | MGI:7296623
Name: CD80 antigen; endonuclease-mediated mutation 1, GemPharmatech Co., Ltd
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
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Allele
Cd80<em2(CD80)Gpt> | MGI:7462065
Name: CD80 antigen; endonuclease-mediated mutation 2, GemPharmatech Co., Ltd
Allele Type: Endonuclease-mediated
Attribute String: Inserted expressed sequence
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Strain
MGI:7593003 | C57BL/6J-Cd80<em2Cya>/Cya
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Strain
MGI:3757555 | NOD.Cg-Prkdc<scid> Tg(Ins2-CD80)3B7Flv
Attribute String: congenic, mutant strain, spontaneous mutation, transgenic
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Strain
MGI:2165492 | NOD.Cg-Prkdc<scid> Tg(Ins2-CD80)3B7Flv/DvsJ
Attribute String: congenic, mutant strain, transgenic
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Publication
29662071 | J:265714
First Author: Cobo-Vuilleumier N
Year: 2018
Journal: Nat Commun
Title: LRH-1 agonism favours an immune-islet dialogue which protects against diabetes mellitus.
Volume: 9
Issue: 1
Pages: 1488
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Strain
MGI:2164710 | B6.129S4-Cd80<tm1Shr> Cd86<tm2Shr>/J
Attribute String: congenic, mutant strain, targeted mutation
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Strain
MGI:7856893 | C.129S4(B6)-Cd80<tm1Shr> Cd86<tm2Shr>
Attribute String: congenic, mutant strain, targeted mutation
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Strain
MGI:4441168 | 129S4/SvJae-Cd80<tm1Shr> Cd86<tm2Shr>/Mmnc
Attribute String: targeted mutation, mutant strain, coisogenic
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Genotype
Genotype
Symbol: Cd80/Cd80 Cd86/Cd86
Background: involves: 129S4/SvJae
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Cd80/Cd80 Cd86/Cd86
Background: involves: 129S4/SvJae * NOD
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Cd80/Cd80 Cd86/Cd86
Background: 129.SJL-Cd86
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Cd80/Cd80 Cd86/Cd86
Background: involves: 129S4/SvJae * C57BL/6J * SJL
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Cd80/Cd80 Cd86/Cd86
Background: involves: 129S4/SvJae * BALB/c
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Cd80/Cd80 Cd86/Cd86
Background: C.129S4(B6)-Cd80 Cd86
Zygosity: cx
Has Mutant Allele: true
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Publication
16210629 | J:119112
First Author: Ueno A
Year: 2005
Journal: J Immunol
Title: Diabetes resistance/susceptibility in T cells of nonobese diabetic mice conferred by MHC and MHC-linked genes.
Volume: 175
Issue: 8
Pages: 5240-7
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Publication
26813254 | J:265967
First Author: Mellado-Gil JM
Year: 2016
Journal: Diabetologia
Title: PAX4 preserves endoplasmic reticulum integrity preventing beta cell degeneration in a mouse model of type 1 diabetes mellitus.
Volume: 59
Issue: 4
Pages: 755-65
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Strain
MGI:4422174 | C.129S4-Cd80<tm1Shr>/Mmmh
Attribute String: targeted mutation, mutant strain, congenic
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Strain
MGI:2164707 | B6.129S4-Cd80<tm1Shr>/J
Attribute String: congenic, mutant strain, targeted mutation
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Strain
MGI:4422194 | SJL.129S4-Cd80<tm1Shr>/Mmmh
Attribute String: congenic, mutant strain, targeted mutation
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Strain
MGI:4418466 | 129S4/SvJae-Cd80<tm1Shr>/Mmnc
Attribute String: coisogenic, mutant strain, targeted mutation
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Strain
MGI:7469108 | BALB/cJGpt-Cd80<em2(CD80)Gpt>/Gpt
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Genotype
Genotype
Symbol: Cd80/Cd80
Background: involves: 129S4/SvJae
Zygosity: hm
Has Mutant Allele: true
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Publication
14670304 | J:86995
First Author: Serra P
Year: 2003
Journal: Immunity
Title: CD40 ligation releases immature dendritic cells from the control of regulatory CD4+CD25+ T cells.
Volume: 19
Issue: 6
Pages: 877-89
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Publication
25287058 | J:346260
First Author: Zeng C
Year: 2014
Journal: J Endocrinol
Title: RNase L contributes to experimentally induced type 1 diabetes onset in mice.
Volume: 223
Issue: 3
Pages: 277-87
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Publication
7534199 | J:189429
First Author: Guerder S
Year: 1994
Journal: Immunity
Title: The role of the T cell costimulator B7-1 in autoimmunity and the induction and maintenance of tolerance to peripheral antigen.
Volume: 1
Issue: 2
Pages: 155-66
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Genotype
Genotype
Symbol: H2-Ab1/H2-Ab1 Tg(Ins2-CD80)3B7Flv/?
Background: involves: 129S2/SvPas * C57BL/6 * CBA
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(Ins2-CD80)3B7Flv/? Tg(Ins2-H2-Ea,Ins2-H2-Eb1)187-7Bri/?
Background: involves: C57BL/6 * CBA/Ca * SJL
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(Ins2-CD80)3B7Flv/? Tg(Ins2-Tnf)17Flv/?
Background: involves: C57BL/6 * CBA/Ca
Zygosity: cx
Has Mutant Allele: true
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Publication
31612266 | J:282630
First Author: Verhagen J
Year: 2019
Journal: Diabetologia
Title: Proinsulin peptide promotes autoimmune diabetes in a novel HLA-DR3-DQ2-transgenic murine model of spontaneous disease.
Volume: 62
Issue: 12
Pages: 2252-2261
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Publication
9725204 | J:93555
First Author: Guerder S
Year: 1998
Journal: J Immunol
Title: Autoimmunity without diabetes in transgenic mice expressing beta cell-specific CD86, but not CD80: parameters that trigger progression to diabetes.
Volume: 161
Issue: 5
Pages: 2128-40
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Strain
MGI:3656073 | B6.Cg-Slc45a2<uw-5J> H2<g7> Tg(Ins2-CD80)3B7Flv
Attribute String: congenic, major histocompatibility congenic, mutant strain, spontaneous mutation, transgenic
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Publication
19208910 | J:151124
First Author: Wong FS
Year: 2009
Journal: Diabetes
Title: Activation of insulin-reactive CD8 T-cells for development of autoimmune diabetes.
Volume: 58
Issue: 5
Pages: 1156-64
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Publication
24353176 | J:209068
First Author: Alkanani AK
Year: 2014
Journal: Diabetes
Title: Induction of diabetes in the RIP-B7.1 mouse model is critically dependent on TLR3 and MyD88 pathways and is associated with alterations in the intestinal microbiome.
Volume: 63
Issue: 2
Pages: 619-31
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Publication
20484136 | J:169352
First Author: Rajasalu T
Year: 2010
Journal: Diabetes
Title: Deficiency in B7-H1 (PD-L1)/PD-1 coinhibition triggers pancreatic beta-cell destruction by insulin-specific, murine CD8 T-cells.
Volume: 59
Issue: 8
Pages: 1966-73
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Strain
MGI:6834804 | B6.Cg-Cd80<tm1Shr> Cd86<tm2Shr> Tg(Cd80)1Hode/J
Attribute String: congenic, mutant strain, targeted mutation, transgenic
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Publication
30237494 | J:310215
First Author: Verhagen J
Year: 2018
Journal: Sci Rep
Title: Proinsulin-mediated induction of type 1 diabetes in HLA-DR4-transgenic mice.
Volume: 8
Issue: 1
Pages: 14106
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Genotype
Genotype
Symbol: H2-Ab1/H2-Ab1 Tg(HLA-DRB1)31Dmz/? Tg(Ins2-CD80)3B7Flv/?
Background: involves: 129S2/SvPas * C57BL/6 * CBA * SJL
Zygosity: cx
Has Mutant Allele: true
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Allele
Tg(GFAP-CD80)9Mdos | MGI:3701469
Name: transgene insertion 9, H Michael Dosch
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Strain
MGI:3701471 | NOD/ShiLt-Tg(GFAP-Cd80)9Mdos/MdosJ
Attribute String: coisogenic, mutant strain, transgenic
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Allele
Tg(Cd80)1Hode | MGI:6834803
Name: transgene insertion 1, Richard Hodes
Allele Type: Transgenic
Attribute String: Conditional ready, Inserted expressed sequence
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Strain
MGI:3052705 | NOD.Cg-Rag1<tm1Mom> Cd86<tm2Shr> Cd80<tm1Shr>/JbsJ
Attribute String: congenic, mutant strain, targeted mutation
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Strain
MGI:4441419 | C.129-Cd40<tm1Kik> Cd86<tm2Shr> Cd80<tm1Shr>/Mmnc
Attribute String: congenic, mutant strain, targeted mutation
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Genotype
Genotype
Symbol: Cd80/Cd80 Cd86/Cd86 Tg(Ighm-Ctla4Ig/Cd80)1Jbs/?
Background: involves: 129S4/SvJae * FVB/N * NOD
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Cd80/Cd80 Cd86/Cd86 Ctla4/Ctla4
Background: involves: 129S4/SvJae * BALB/c
Zygosity: cx
Has Mutant Allele: true
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Strain
MGI:2653205 | NOD.129(B6)-Rag1<tm1Mom> Cd80<tm1Shr>/JbsJ
Attribute String: congenic, mutant strain, targeted mutation
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Strain
MGI:5085858 | B6.129S4-Cd80<tm1Shr> Cd86<tm1Shr>
Attribute String: targeted mutation, mutant strain, congenic
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Strain
MGI:4422176 | C.129S4-Cd80<tm1Shr> Cd86<tm1Shr>/Mmmh
Attribute String: targeted mutation, mutant strain, congenic
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Strain
MGI:4422196 | SJL.129S4-Cd80<tm1Shr> Cd86<tm1Shr>/Mmmh
Attribute String: congenic, mutant strain, targeted mutation
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Genotype
Genotype
Symbol: Cd80/Cd80 Cd86/Cd86
Background: B6.129S4-Cd80 Cd86
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Rag1/Rag1 Cd80/Cd80
Background: NOD.129(B6)-Rag1 Cd80/JbsJ
Zygosity: cx
Has Mutant Allele: true
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Strain
MGI:3623435 | B6.Cg-Tg(HLA-DQA1,HLA-DQB1)1Dv Tg(Ins2-CD80)3B7Flv
Attribute String: transgenic, mutant strain, congenic
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Publication
12917255 | J:85223
First Author: Rajagopalan G
Year: 2003
Journal: Int Immunol
Title: Autoimmune diabetes in HLA-DR3/DQ8 transgenic mice expressing the co-stimulatory molecule B7-1 in the beta cells of islets of Langerhans.
Volume: 15
Issue: 9
Pages: 1035-44
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Genotype
Genotype
Symbol: Tg(HLA-DQA1,HLA-DQB1)1Dv/? Tg(Ins2-CD80)3B7Flv/?
Background: B6.Cg-Tg(HLA-DQA1,HLA-DQB1)1Dv Tg(Ins2-CD80)3B7Flv
Zygosity: cx
Has Mutant Allele: true
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Protein Coding Gene
MGI:1922056 | Tmem106a
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
12361980 | J:109851
First Author: Marron MP
Year: 2002
Journal: Proc Natl Acad Sci U S A
Title: Functional evidence for the mediation of diabetogenic T cell responses by HLA-A2.1 MHC class I molecules through transgenic expression in NOD mice.
Volume: 99
Issue: 21
Pages: 13753-8
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Strain
MGI:3623433 | B6.Cg-H2-Ab1<b-tm1Gru> Tg(HLA-DQA1,HLA-DQB1)1Dv Tg(Ins2-CD80)3B7Flv
Attribute String: congenic, mutant strain, targeted mutation, transgenic
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Publication
15240665 | J:91915
First Author: Havari E
Year: 2004
Journal: J Immunol
Title: Expression of the B7.1 costimulatory molecule on pancreatic beta cells abrogates the requirement for CD4 T cells in the development of type 1 diabetes.
Volume: 173
Issue: 2
Pages: 787-96
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Publication
10620608 | J:59245
First Author: Wen L
Year: 2000
Journal: J Exp Med
Title: In vivo evidence for the contribution of human histocompatibility leukocyte antigen (HLA)-DQ molecules to the development of diabetes.
Volume: 191
Issue: 1
Pages: 97-104
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Genotype
Genotype
Symbol: H2-Ab1/H2-Ab1 Tg(HLA-DQA1,HLA-DQB1)1Dv/? Tg(Ins2-CD80)3B7Flv/?
Background: B6.Cg-H2-Ab1 Tg(HLA-DQA1,HLA-DQB1)1Dv Tg(Ins2-CD80)3B7Flv
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: H2-Ab1/H2-Ab1 Tg(HLA-DQA1,HLA-DQB1)1Dv/? Tg(Ins2-CD80)3B7Flv/?
Background: involves: 129S2/SvPas * C57BL/6 * C57BL/10SnJ * CBA
Zygosity: cx
Has Mutant Allele: true
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Allele
Tg(Ins1-Cd80)378Psoh | MGI:5569013
Name: transgene insertion 378, Pamela Ohashi
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Strain
MGI:4422200 | 129S4/SvJae-Cd80<tm1Shr> Cd86<tm1Shr> Ctla4<tm1Shr>/Mmmh
Attribute String: targeted mutation, mutant strain, coisogenic
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Publication
11285306 | J:68641
First Author: Wen L
Year: 2001
Journal: J Clin Invest
Title: The regulatory role of DR4 in a spontaneous diabetes DQ8 transgenic model.
Volume: 107
Issue: 7
Pages: 871-80
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Publication
10607745 | J:164342
First Author: Allison J
Year: 2000
Journal: Int Immunol
Title: Transgenic overexpression of human Bcl-2 in islet beta cells inhibits apoptosis but does not prevent autoimmune destruction.
Volume: 12
Issue: 1
Pages: 9-17
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Genotype
Genotype
Symbol: H2-Ab1/H2-Ab1 Tg(HLA-DQA1,HLA-DQB1)1Dv/? Tg(HLA-DRB1)31Dmz/? Tg(Ins2-CD80)3B7Flv/?
Background: involves: 129S2/SvPas * C57BL/6 * C57BL/10SnJ * CBA * SJL
Zygosity: cx
Has Mutant Allele: true
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Allele
Tg(Igh-6-Cd80)1Gjf | MGI:3656398
Name: transgene insertion 1, Gordon J Freeman
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Publication
31266981 | J:283724
First Author: Bru-Tari E
Year: 2019
Journal: Sci Rep
Title: Pancreatic alpha-cell mass in the early-onset and advanced stage of a mouse model of experimental autoimmune diabetes.
Volume: 9
Issue: 1
Pages: 9515
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Genotype
Genotype
Symbol: Tg(Ins1-Cd80)378Psoh/?
Background: involves: FVB/N
Zygosity: ot
Has Mutant Allele: true
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Protein Coding Gene
MGI:1924375 | Il33
Type: protein_coding_gene
Organism: mouse, laboratory
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Allele
Cd86<tm2Shr> | MGI:2159105
Name: CD86 antigen; targeted mutation 2, Arlene H Sharpe
Allele Type: Targeted
Attribute String: Null/knockout
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Strain
MGI:3772774 | NOD.FVB-Tg(Igh-6-Cd80)1Gjf/JbsJ
Attribute String: congenic, mutant strain, transgenic
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Strain
MGI:3662849 | B6.Cg-Tg(Igh-6-Cd80)1Gjf
Attribute String: transgenic, mutant strain, congenic
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Publication
7533646 | J:112474
First Author: Sethna MP
Year: 1994
Journal: Immunity
Title: A negative regulatory function of B7 revealed in B7-1 transgenic mice.
Volume: 1
Issue: 5
Pages: 415-21
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Genotype
Genotype
Symbol: Tg(Igh-6-Cd80)1Gjf/?
Background: involves: FVB
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(Igh-6-Cd80)1Gjf/?
Background: B6.Cg-Tg(Igh-6-Cd80)1Gjf
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(Igh-6-Cd80)1Gjf/?
Background: involves: BALB/c * C57BL/6 * CBA
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(Igh-6-Cd80)1Gjf/?
Background: NOD.FVB-Tg(Igh-6-Cd80)1Gjf/JbsJ
Zygosity: ot
Has Mutant Allele: true
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Strain
MGI:3621296 | 129.SJL-Cd86<tm2Shr>
Attribute String: targeted mutation, mutant strain, congenic
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Publication
17804511 | J:129927
First Author: Thebeau LG
Year: 2007
Journal: J Virol
Title: B7 costimulation molecules expressed from the herpes simplex virus 2 genome rescue immune induction in B7-deficient mice.
Volume: 81
Issue: 22
Pages: 12200-9
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Strain
MGI:4355728 | NOD.Cg-Tg(Igh-6-Cd80)1Gjf Dst<dt-39J>/GrsrJ
Attribute String: congenic, mutant strain, spontaneous mutation, transgenic
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Genotype
Genotype
Symbol: Tg(Ins1-Cd80)378Psoh/? Tg(TcrLCMV)327Sdz/?
Background: involves: C57BL/6 * DBA/2 * FVB/N
Zygosity: cx
Has Mutant Allele: true
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