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Search results 401 to 500 out of 513 for Cdh16

0.034s
Type Details Score
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Cdh16-cre)91Igr/?
Background: involves: 129S4/SvJaeSor * C57BL/6 * ICR
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Tg(CAG-Bgeo/GFP)21Lbe/? Tg(Cdh16-cre/ERT2)F427Djmp/?
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Cdh16-cre)91Igr/?
Background: B6.Cg-Gt(ROSA)26Sor Tg(Cdh16-cre)91Igr
Zygosity: cn
Has Mutant Allele: true
Publication
First Author: Pollard PJ
Year: 2007
Journal: Cancer Cell
Title: Targeted inactivation of fh1 causes proliferative renal cyst development and activation of the hypoxia pathway.
Volume: 11
Issue: 4
Pages: 311-9
Publication
First Author: Adam J
Year: 2011
Journal: Cancer Cell
Title: Renal cyst formation in Fh1-deficient mice is independent of the Hif/Phd pathway: roles for fumarate in KEAP1 succination and Nrf2 signaling.
Volume: 20
Issue: 4
Pages: 524-37
Publication
First Author: Zhou HL
Year: 2019
Journal: Nature
Title: Metabolic reprogramming by the S-nitroso-CoA reductase system protects against kidney injury.
Volume: 565
Issue: 7737
Pages: 96-100
Publication  
First Author: Lakhia R
Year: 2020
Journal: JCI Insight
Title: Interstitial microRNA miR-214 attenuates inflammation and polycystic kidney disease progression.
Volume: 5
Issue: 7
Publication
First Author: Ferrè S
Year: 2019
Journal: Kidney Int
Title: Renal tubular cell spliced X-box binding protein 1 (Xbp1s) has a unique role in sepsis-induced acute kidney injury and inflammation.
Volume: 96
Issue: 6
Pages: 1359-1373
Publication
First Author: Gresh L
Year: 2004
Journal: EMBO J
Title: A transcriptional network in polycystic kidney disease.
Volume: 23
Issue: 7
Pages: 1657-68
Publication
First Author: Lin F
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Kidney-specific inactivation of the KIF3A subunit of kinesin-II inhibits renal ciliogenesis and produces polycystic kidney disease.
Volume: 100
Issue: 9
Pages: 5286-91
Publication
First Author: Li L
Year: 2012
Journal: Am J Physiol Regul Integr Comp Physiol
Title: Salt sensitivity of nitric oxide generation and blood pressure in mice with targeted knockout of the insulin receptor from the renal tubule.
Volume: 303
Issue: 5
Pages: R505-12
Publication
First Author: Wang X
Year: 2018
Journal: Am J Physiol Renal Physiol
Title: Physiological functions of ferroportin in the regulation of renal iron recycling and ischemic acute kidney injury.
Volume: 315
Issue: 4
Pages: F1042-F1057
Publication
First Author: Hoefflin R
Year: 2020
Journal: Nat Commun
Title: HIF-1α and HIF-2α differently regulate tumour development and inflammation of clear cell renal cell carcinoma in mice.
Volume: 11
Issue: 1
Pages: 4111
Publication
First Author: Guinot A
Year: 2016
Journal: J Pathol
Title: Combined deletion of Vhl, Trp53 and Kif3a causes cystic and neoplastic renal lesions.
Volume: 239
Issue: 3
Pages: 365-73
Publication
First Author: Schönenberger D
Year: 2016
Journal: Cancer Res
Title: Formation of Renal Cysts and Tumors in Vhl/Trp53-Deficient Mice Requires HIF1α and HIF2α.
Volume: 76
Issue: 7
Pages: 2025-36
Publication
First Author: Fu H
Year: 2021
Journal: iScience
Title: The hepatocyte growth factor/c-met pathway is a key determinant of the fibrotic kidney local microenvironment.
Volume: 24
Issue: 10
Pages: 103112
Publication
First Author: Wang X
Year: 2024
Journal: FASEB J
Title: MiR-21 suppression in macrophages promotes M2-like polarization and attenuates kidney ischemia-reperfusion injury.
Volume: 38
Issue: 23
Pages: e70251
Publication
First Author: Lehmann H
Year: 2015
Journal: J Am Soc Nephrol
Title: Combined Deletion of Vhl and Kif3a Accelerates Renal Cyst Formation.
Volume: 26
Issue: 11
Pages: 2778-88
Publication
First Author: Frew IJ
Year: 2008
Journal: EMBO J
Title: pVHL and PTEN tumour suppressor proteins cooperatively suppress kidney cyst formation.
Volume: 27
Issue: 12
Pages: 1747-57
Publication
First Author: Bhagat TD
Year: 2017
Journal: J Biol Chem
Title: Notch Pathway Is Activated via Genetic and Epigenetic Alterations and Is a Therapeutic Target in Clear Cell Renal Cancer.
Volume: 292
Issue: 3
Pages: 837-846
Publication
First Author: Paragas N
Year: 2014
Journal: J Clin Invest
Title: α-Intercalated cells defend the urinary system from bacterial infection.
Volume: 124
Issue: 7
Pages: 2963-76
Publication
First Author: Li Y
Year: 2021
Journal: Cell Death Differ
Title: GSDME-mediated pyroptosis promotes inflammation and fibrosis in obstructive nephropathy.
Volume: 28
Issue: 8
Pages: 2333-2350
Publication
First Author: Joshi A
Year: 2015
Journal: Am J Pathol
Title: Activated mutant p110α causes endometrial carcinoma in the setting of biallelic Pten deletion.
Volume: 185
Issue: 4
Pages: 1104-13
Publication
First Author: Palicharla VR
Year: 2023
Journal: Mol Biol Cell
Title: Interactions between TULP3 tubby domain and ARL13B amphipathic helix promote lipidated protein transport to cilia.
Volume: 34
Issue: 3
Pages: ar18
Publication
First Author: Olauson H
Year: 2012
Journal: J Am Soc Nephrol
Title: Targeted deletion of Klotho in kidney distal tubule disrupts mineral metabolism.
Volume: 23
Issue: 10
Pages: 1641-51
Publication
First Author: Chen L
Year: 2015
Journal: J Clin Invest
Title: Macrophage migration inhibitory factor promotes cyst growth in polycystic kidney disease.
Volume: 125
Issue: 6
Pages: 2399-412
Publication
First Author: Clerici S
Year: 2024
Journal: EMBO Mol Med
Title: Inhibition of asparagine synthetase effectively retards polycystic kidney disease progression.
Volume: 16
Issue: 6
Pages: 1379-1403
Publication
First Author: Hasumi H
Year: 2012
Journal: J Natl Cancer Inst
Title: Regulation of mitochondrial oxidative metabolism by tumor suppressor FLCN.
Volume: 104
Issue: 22
Pages: 1750-64
Publication
First Author: Adam J
Year: 2017
Journal: Cell Rep
Title: Fumarate Hydratase Deletion in Pancreatic β Cells Leads to Progressive Diabetes.
Volume: 20
Issue: 13
Pages: 3135-3148
Publication
First Author: Bonucci M
Year: 2020
Journal: Nat Commun
Title: mTOR and S6K1 drive polycystic kidney by the control of Afadin-dependent oriented cell division.
Volume: 11
Issue: 1
Pages: 3200
Publication  
First Author: Ramani K
Year: 2018
Journal: JCI Insight
Title: Unexpected kidney-restricted role for IL-17 receptor signaling in defense against systemic Candida albicans infection.
Volume: 3
Issue: 9
Publication
First Author: Faria D
Year: 2014
Journal: Kidney Int
Title: The calcium-activated chloride channel Anoctamin 1 contributes to the regulation of renal function.
Volume: 85
Issue: 6
Pages: 1369-81
Publication
First Author: Di Malta C
Year: 2023
Journal: EMBO Mol Med
Title: TFEB and TFE3 drive kidney cystogenesis and tumorigenesis.
Volume: 15
Issue: 5
Pages: e16877
Publication
First Author: Alesi N
Year: 2024
Journal: Nat Commun
Title: TFEB drives mTORC1 hyperactivation and kidney disease in Tuberous Sclerosis Complex.
Volume: 15
Issue: 1
Pages: 406
Publication    
First Author: Calcagnì A
Year: 2016
Journal: Elife
Title: Modelling TFE renal cell carcinoma in mice reveals a critical role of WNT signaling.
Volume: 5
Publication
First Author: Cai Y
Year: 2014
Journal: J Clin Invest
Title: Altered trafficking and stability of polycystins underlie polycystic kidney disease.
Volume: 124
Issue: 12
Pages: 5129-44
Publication
First Author: Conduit SE
Year: 2020
Journal: Hum Mol Genet
Title: AKT signaling promotes DNA damage accumulation and proliferation in polycystic kidney disease.
Volume: 29
Issue: 1
Pages: 31-48
Publication
First Author: Shillingford JM
Year: 2023
Journal: Am J Physiol Renal Physiol
Title: Functional TFEB activation characterizes multiple models of renal cystic disease and loss of polycystin-1.
Volume: 324
Issue: 4
Pages: F404-F422
Publication
First Author: Schell C
Year: 2016
Journal: Am J Pathol
Title: The Rapamycin-Sensitive Complex of Mammalian Target of Rapamycin Is Essential to Maintain Male Fertility.
Volume: 186
Issue: 2
Pages: 324-36
Publication
First Author: Lee HW
Year: 2015
Journal: Am J Physiol Renal Physiol
Title: Effect of dietary protein restriction on renal ammonia metabolism.
Volume: 308
Issue: 12
Pages: F1463-73
Publication
First Author: Li LX
Year: 2017
Journal: J Clin Invest
Title: Lysine methyltransferase SMYD2 promotes cyst growth in autosomal dominant polycystic kidney disease.
Volume: 127
Issue: 7
Pages: 2751-2764
Publication
First Author: Zhou X
Year: 2013
Journal: J Clin Invest
Title: Sirtuin 1 inhibition delays cyst formation in autosomal-dominant polycystic kidney disease.
Volume: 123
Issue: 7
Pages: 3084-98
Publication
First Author: Rowe I
Year: 2013
Journal: Nat Med
Title: Defective glucose metabolism in polycystic kidney disease identifies a new therapeutic strategy.
Volume: 19
Issue: 4
Pages: 488-93
Publication
First Author: Jin H
Year: 2020
Journal: Am J Pathol
Title: Innate Immune Signaling Contributes to Tubular Cell Senescence in the Glis2 Knockout Mouse Model of Nephronophthisis.
Volume: 190
Issue: 1
Pages: 176-189
Publication  
First Author: Wang R
Year: 2021
Journal: JCI Insight
Title: Pdcd10-Stk24/25 complex controls kidney water reabsorption by regulating Aqp2 membrane targeting.
Volume: 6
Issue: 12
Publication
First Author: Napolitano G
Year: 2020
Journal: Nature
Title: A substrate-specific mTORC1 pathway underlies Birt-Hogg-Dubé syndrome.
Volume: 585
Issue: 7826
Pages: 597-602
Publication
First Author: Chu PY
Year: 2013
Journal: PLoS One
Title: SPAK deficiency corrects pseudohypoaldosteronism II caused by WNK4 mutation.
Volume: 8
Issue: 9
Pages: e72969
Publication
First Author: Grahammer F
Year: 2016
Journal: J Clin Invest
Title: mTORC2 critically regulates renal potassium handling.
Volume: 126
Issue: 5
Pages: 1773-82
Publication
First Author: Polgar N
Year: 2015
Journal: Am J Physiol Cell Physiol
Title: The exocyst gene Sec10 regulates renal epithelial monolayer homeostasis and apoptotic sensitivity.
Volume: 309
Issue: 3
Pages: C190-201
Genotype
Symbol: Pten/Pten Vhl/Vhl Tg(Cdh16-cre)91Igr/?
Background: involves: 129S4/SvJae * ICR
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Pten/Pten Vhl/Vhl Tg(Cdh16-cre)91Igr/?
Background: involves: 129S4/SvJae * BALB/c * C57BL/6J * ICR
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Kif3a/Kif3a Tg(Cdh16-cre)91Igr/?
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * ICR
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Ctnnb1/Ctnnb1<+> Wnt9b/Wnt9b Tg(Cdh16-cre)91Igr/?
Background: involves: 129X1/SvJ * ICR
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Exoc5/Exoc5 Tg(Cdh16-cre)91Igr/?
Background: involves: 129S4/SvJaeSor * C57BL/6N * ICR
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Flcn/Flcn Tfeb/Tfeb Tg(Cdh16-cre)91Igr/?
Background: involves: 129S4/SvJaeSor * C57BL/6 * ICR
Zygosity: cn
Has Mutant Allele: true
Publication
First Author: Seixas C
Year: 2016
Journal: Mol Biol Cell
Title: Arl13b and the exocyst interact synergistically in ciliogenesis.
Volume: 27
Issue: 2
Pages: 308-20
Publication
First Author: Baba M
Year: 2008
Journal: J Natl Cancer Inst
Title: Kidney-targeted Birt-Hogg-Dube gene inactivation in a mouse model: Erk1/2 and Akt-mTOR activation, cell hyperproliferation, and polycystic kidneys.
Volume: 100
Issue: 2
Pages: 140-54
Publication
First Author: Hasumi H
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: Folliculin-interacting proteins Fnip1 and Fnip2 play critical roles in kidney tumor suppression in cooperation with Flcn.
Volume: 112
Issue: 13
Pages: E1624-31
Publication
First Author: Murtha MJ
Year: 2018
Journal: J Clin Invest
Title: Insulin receptor signaling regulates renal collecting duct and intercalated cell antibacterial defenses.
Volume: 128
Issue: 12
Pages: 5634-5646
Publication  
First Author: Hajarnis S
Year: 2017
Journal: Nat Commun
Title: microRNA-17 family promotes polycystic kidney disease progression through modulation of mitochondrial metabolism.
Volume: 8
Pages: 14395
Publication
First Author: Karner CM
Year: 2009
Journal: Nat Genet
Title: Wnt9b signaling regulates planar cell polarity and kidney tubule morphogenesis.
Volume: 41
Issue: 7
Pages: 793-9
Publication  
First Author: Viau A
Year: 2018
Journal: EMBO J
Title: Cilia-localized LKB1 regulates chemokine signaling, macrophage recruitment, and tissue homeostasis in the kidney.
Volume: 37
Issue: 15
Publication
First Author: Mukherjee M
Year: 2020
Journal: Dev Biol
Title: Foxi1 inactivation rescues loss of principal cell fate selection in Hes1-deficient kidneys but does not ensure maintenance of principal cell gene expression.
Volume: 466
Issue: 1-2
Pages: 1-11
Publication
First Author: Frew IJ
Year: 2008
Journal: Mol Cell Biol
Title: Combined VHLH and PTEN mutation causes genital tract cystadenoma and squamous metaplasia.
Volume: 28
Issue: 14
Pages: 4536-48
Publication
First Author: Fischer E
Year: 2006
Journal: Nat Genet
Title: Defective planar cell polarity in polycystic kidney disease.
Volume: 38
Issue: 1
Pages: 21-3
Publication  
First Author: Menezes LF
Year: 2016
Journal: EBioMedicine
Title: Fatty Acid Oxidation is Impaired in An Orthologous Mouse Model of Autosomal Dominant Polycystic Kidney Disease.
Volume: 5
Pages: 183-92
Publication
First Author: Grande MT
Year: 2015
Journal: Nat Med
Title: Snail1-induced partial epithelial-to-mesenchymal transition drives renal fibrosis in mice and can be targeted to reverse established disease.
Volume: 21
Issue: 9
Pages: 989-97
Publication
First Author: Guitart AV
Year: 2017
Journal: J Exp Med
Title: Fumarate hydratase is a critical metabolic regulator of hematopoietic stem cell functions.
Volume: 214
Issue: 3
Pages: 719-735
Publication
First Author: Li A
Year: 2017
Journal: J Cell Mol Med
Title: Rapamycin treatment dose-dependently improves the cystic kidney in a new ADPKD mouse model via the mTORC1 and cell-cycle-associated CDK1/cyclin axis.
Volume: 21
Issue: 8
Pages: 1619-1635
Publication  
First Author: Han X
Year: 2020
Journal: J Mol Cell Cardiol
Title: FGF23 induced left ventricular hypertrophy mediated by FGFR4 signaling in the myocardium is attenuated by soluble Klotho in mice.
Volume: 138
Pages: 66-74
Publication
First Author: Shi M
Year: 2018
Journal: Am J Physiol Renal Physiol
Title: Effects of erythropoietin receptor activity on angiogenesis, tubular injury, and fibrosis in acute kidney injury: a "U-shaped" relationship.
Volume: 314
Issue: 4
Pages: F501-F516
Publication
First Author: Zhang J
Year: 2016
Journal: J Am Soc Nephrol
Title: Competing Actions of Type 1 Angiotensin II Receptors Expressed on T Lymphocytes and Kidney Epithelium during Cisplatin-Induced AKI.
Volume: 27
Issue: 8
Pages: 2257-64
Publication
First Author: Patel V
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: miR-17~92 miRNA cluster promotes kidney cyst growth in polycystic kidney disease.
Volume: 110
Issue: 26
Pages: 10765-70
Publication      
First Author: Mittermeier L
Year: 2019
Journal: Proc Natl Acad Sci U S A
Title: TRPM7 is the central gatekeeper of intestinal mineral absorption essential for postnatal survival.
Publication
First Author: Li Y
Year: 2016
Journal: J Am Soc Nephrol
Title: Deletion of ADP Ribosylation Factor-Like GTPase 13B Leads to Kidney Cysts.
Volume: 27
Issue: 12
Pages: 3628-3638
Publication
First Author: Huang S
Year: 2018
Journal: PLoS Biol
Title: Jagged1/Notch2 controls kidney fibrosis via Tfam-mediated metabolic reprogramming.
Volume: 16
Issue: 9
Pages: e2005233
Publication
First Author: Weisser I
Year: 2024
Journal: J Am Soc Nephrol
Title: Ablation of Long Noncoding RNA Hoxb3os Exacerbates Cystogenesis in Mouse Polycystic Kidney Disease.
Volume: 35
Issue: 1
Pages: 41-55
Publication  
First Author: Lee AJ
Year: 2016
Journal: Sci Rep
Title: Fibroproliferative response to urothelial failure obliterates the ureter lumen in a mouse model of prenatal congenital obstructive nephropathy.
Volume: 6
Pages: 31137
Publication
First Author: Dionne LK
Year: 2018
Journal: J Cell Biol
Title: Centrosome amplification disrupts renal development and causes cystogenesis.
Volume: 217
Issue: 7
Pages: 2485-2501
Publication  
First Author: Cognard N
Year: 2015
Journal: Cilia
Title: Comparing the Bbs10 complete knockout phenotype with a specific renal epithelial knockout one highlights the link between renal defects and systemic inactivation in mice.
Volume: 4
Pages: 10
Publication
First Author: Ramalingam H
Year: 2021
Journal: Cell Metab
Title: A methionine-Mettl3-N6-methyladenosine axis promotes polycystic kidney disease.
Volume: 33
Issue: 6
Pages: 1234-1247.e7
Protein
Organism: Mus musculus/domesticus
Length: 830  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 815  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 223  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 830  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 163  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 142  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 141  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 800  
Fragment?: false
Publication
First Author: Fedeles SV
Year: 2011
Journal: Nat Genet
Title: A genetic interaction network of five genes for human polycystic kidney and liver diseases defines polycystin-1 as the central determinant of cyst formation.
Volume: 43
Issue: 7
Pages: 639-47
Publication
First Author: Karner CM
Year: 2011
Journal: Development
Title: Canonical Wnt9b signaling balances progenitor cell expansion and differentiation during kidney development.
Volume: 138
Issue: 7
Pages: 1247-57
Publication    
First Author: Werth M
Year: 2017
Journal: Elife
Title: Transcription factor TFCP2L1 patterns cells in the mouse kidney collecting ducts.
Volume: 6
Publication
First Author: Lakhia R
Year: 2016
Journal: J Am Soc Nephrol
Title: MicroRNA-21 Aggravates Cyst Growth in a Model of Polycystic Kidney Disease.
Volume: 27
Issue: 8
Pages: 2319-30
Publication
First Author: Shibazaki S
Year: 2008
Journal: Hum Mol Genet
Title: Cyst formation and activation of the extracellular regulated kinase pathway after kidney specific inactivation of Pkd1.
Volume: 17
Issue: 11
Pages: 1505-16
Publication
First Author: Smith CB
Year: 2022
Journal: J Biol Rhythms
Title: Cell-Type-Specific Circadian Bioluminescence Rhythms in Dbp Reporter Mice.
Volume: 37
Issue: 1
Pages: 53-77
Publication
First Author: Liang L
Year: 2014
Journal: Mol Endocrinol
Title: Androgen receptor enhances kidney stone-CaOx crystal formation via modulation of oxalate biosynthesis & oxidative stress.
Volume: 28
Issue: 8
Pages: 1291-303
Publication      
First Author: Smith CR
Year: 2021
Journal: bioRxiv
Title: Cell-type specific circadian bioluminescence rjutj,s om Dbp reporter mice
Publication
First Author: Landrette SF
Year: 2011
Journal: PLoS One
Title: piggyBac transposon somatic mutagenesis with an activated reporter and tracker (PB-SMART) for genetic screens in mice.
Volume: 6
Issue: 10
Pages: e26650
Publication    
First Author: Chubanov V
Year: 2016
Journal: Elife
Title: Epithelial magnesium transport by TRPM6 is essential for prenatal development and adult survival.
Volume: 5
Publication
First Author: de Souza Cordeiro LM
Year: 2022
Journal: Diabetologia
Title: Loss of function of renal Glut2 reverses hyperglycaemia and normalises body weight in mouse models of diabetes and obesity.
Volume: 65
Issue: 6
Pages: 1032-1047