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Search results 401 to 494 out of 494 for Ctla4

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Categories

Hits by Pathway

Hits by Category

Hits by Strain

Type Details Score
Publication
1675432 | J:3351
First Author: Todd JA
Year: 1991
Journal: Nature
Title: Genetic analysis of autoimmune type 1 diabetes mellitus in mice.
Volume: 351
Issue: 6327
Pages: 542-7
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Strain
MGI:6355292 | C57BL/6JSmoc-Ctla4<em1(CTLA4)Smoc> Tnfrsf4<em3(TNFRSF4)Smoc>/Smoc
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
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Protein Coding Gene
MGI:99147 | Yes1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein
Q04736
Organism: Mus musculus/domesticus
Length: 541  
Fragment?: false
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Publication
17675493 | J:151221
First Author: Nguyen CQ
Year: 2007
Journal: J Immunol
Title: Development of Sjogren's syndrome in nonobese diabetic-derived autoimmune-prone C57BL/6.NOD-Aec1Aec2 mice is dependent on complement component-3.
Volume: 179
Issue: 4
Pages: 2318-29
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Publication
9257847 | J:42103
First Author: Podolin PL
Year: 1997
Journal: J Immunol
Title: Congenic mapping of the insulin-dependent diabetes (Idd) gene, Idd10, localizes two genes mediating the Idd10 effect and eliminates the candidate Fcgr1.
Volume: 159
Issue: 4
Pages: 1835-43
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Protein Coding Gene
MGI:96756 | Lck
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein
P06240
Organism: Mus musculus/domesticus
Length: 509  
Fragment?: false
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Publication
30556232 | J:272950
First Author: Sopel N
Year: 2019
Journal: Immunology
Title: Immunoregulatory role of acid sphingomyelinase in allergic asthma.
Volume: 156
Issue: 4
Pages: 373-383
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Publication
21167754 | J:167720
First Author: Kerdiles YM
Year: 2010
Journal: Immunity
Title: Foxo transcription factors control regulatory T cell development and function.
Volume: 33
Issue: 6
Pages: 890-904
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Publication
26433463 | J:317256
First Author: Colbeck EJ
Year: 2015
Journal: Oncotarget
Title: Eliminating roles for T-bet and IL-2 but revealing superior activation and proliferation as mechanisms underpinning dominance of regulatory T cells in tumors.
Volume: 6
Issue: 28
Pages: 24649-59
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Publication
29434354 | J:282414
First Author: Zemmour D
Year: 2018
Journal: Nat Immunol
Title: Single-cell gene expression reveals a landscape of regulatory T cell phenotypes shaped by the TCR.
Volume: 19
Issue: 3
Pages: 291-301
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Publication
34450252 | J:347744
First Author: Wixler V
Year: 2022
Journal: Mol Ther
Title: Small spleen peptides prevent development of psoriatic arthritis via restoration of peripheral tolerance.
Volume: 30
Issue: 2
Pages: 745-762
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Publication
17621372 | J:123539
First Author: Pillemer BB
Year: 2007
Journal: Eur J Immunol
Title: Deficient SOCS3 expression in CD4+CD25+FoxP3+ regulatory T cells and SOCS3-mediated suppression of Treg function.
Volume: 37
Issue: 8
Pages: 2082-9
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Publication
29757192 | J:262726
First Author: Li XY
Year: 2018
Journal: J Clin Invest
Title: CD155 loss enhances tumor suppression via combined host and tumor-intrinsic mechanisms.
Volume: 128
Issue: 6
Pages: 2613-2625
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Publication
33687987 | J:305679
First Author: Alteber Z
Year: 2021
Journal: Cancer Discov
Title: Therapeutic Targeting of Checkpoint Receptors within the DNAM1 Axis.
Volume: 11
Issue: 5
Pages: 1040-1051
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Protein Coding Gene
MGI:2388479 | Ppp2r5a
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:95602 | Fyn
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1349473 | Ppp2r5e
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1349475 | Ppp2r5c
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:2388480 | Ppp2r5b
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:96892 | Lyn
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein
Q6PD03
Organism: Mus musculus/domesticus
Length: 486  
Fragment?: false
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Protein
Q6PD28
Organism: Mus musculus/domesticus
Length: 497  
Fragment?: false
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Protein
Q60996
Organism: Mus musculus/domesticus
Length: 524  
Fragment?: false
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Protein
Q61151
Organism: Mus musculus/domesticus
Length: 467  
Fragment?: false
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Protein
P25911
Organism: Mus musculus/domesticus
Length: 512  
Fragment?: false
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Protein
P39688
Organism: Mus musculus/domesticus
Length: 537  
Fragment?: false
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Publication
19017930 | J:142211
First Author: Wilson EB
Year: 2008
Journal: J Immunol
Title: Cutting edge: CD4+ T cell-derived IL-2 is essential for help-dependent primary CD8+ T cell responses.
Volume: 181
Issue: 11
Pages: 7445-8
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Publication
17277778 | J:120349
First Author: Yamanouchi J
Year: 2007
Journal: Nat Genet
Title: Interleukin-2 gene variation impairs regulatory T cell function and causes autoimmunity.
Volume: 39
Issue: 3
Pages: 329-37
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Publication
12759418 | J:85823
First Author: Matsuki N
Year: 2003
Journal: J Immunol
Title: Genetic dissection of V alpha 14J alpha 18 natural T cell number and function in autoimmune-prone mice.
Volume: 170
Issue: 11
Pages: 5429-37
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Publication
21813777 | J:179269
First Author: Baban B
Year: 2011
Journal: J Immunol
Title: Physiologic control of IDO competence in splenic dendritic cells.
Volume: 187
Issue: 5
Pages: 2329-35
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Publication
10395655 | J:119892
First Author: Wu ZQ
Year: 1999
Journal: J Immunol
Title: In vivo polysaccharide-specific IgG isotype responses to intact Streptococcus pneumoniae are T cell dependent and require CD40- and B7-ligand interactions.
Volume: 163
Issue: 2
Pages: 659-67
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Publication
34848557 | J:321567
First Author: Wu MJ
Year: 2022
Journal: Cancer Discov
Title: Mutant IDH Inhibits IFNγ-TET2 Signaling to Promote Immunoevasion and Tumor Maintenance in Cholangiocarcinoma.
Volume: 12
Issue: 3
Pages: 812-835
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Publication
9653097 | J:111538
First Author: Fallarino F
Year: 1998
Journal: J Exp Med
Title: B7-1 engagement of cytotoxic T lymphocyte antigen 4 inhibits T cell activation in the absence of CD28.
Volume: 188
Issue: 1
Pages: 205-10
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Publication
12496383 | J:135141
First Author: Gärdby E
Year: 2003
Journal: J Immunol
Title: Strong differential regulation of serum and mucosal IgA responses as revealed in CD28-deficient mice using cholera toxin adjuvant.
Volume: 170
Issue: 1
Pages: 55-63
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Publication
22733595 | J:187942
First Author: Ueno T
Year: 2012
Journal: Eur J Immunol
Title: Intact B7-H3 signaling promotes allograft prolongation through preferential suppression of Th1 effector responses.
Volume: 42
Issue: 9
Pages: 2343-53
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Publication
29212910 | J:257357
First Author: Shi B
Year: 2018
Journal: J Immunol
Title: Foxp1 Negatively Regulates T Follicular Helper Cell Differentiation and Germinal Center Responses by Controlling Cell Migration and CTLA-4.
Volume: 200
Issue: 2
Pages: 586-594
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Publication
10569763 | J:58540
First Author: Heinzel FP
Year: 1999
Journal: Infect Immun
Title: Interleukin-4-independent acceleration of cutaneous leishmaniasis in susceptible BALB/c mice following treatment with anti-CTLA4 antibody.
Volume: 67
Issue: 12
Pages: 6454-60
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Publication
23956428 | J:205876
First Author: Deppong CM
Year: 2013
Journal: J Immunol
Title: CTLA4Ig inhibits effector T cells through regulatory T cells and TGF-β.
Volume: 191
Issue: 6
Pages: 3082-9
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Publication
15351783 | J:93639
First Author: Mellor AL
Year: 2004
Journal: Int Immunol
Title: Specific subsets of murine dendritic cells acquire potent T cell regulatory functions following CTLA4-mediated induction of indoleamine 2,3 dioxygenase.
Volume: 16
Issue: 10
Pages: 1391-401
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Publication
24338929 | J:209288
First Author: Kowalczyk A
Year: 2014
Journal: Eur J Immunol
Title: Cell-extrinsic CTLA4-mediated regulation of dendritic cell maturation depends on STAT3.
Volume: 44
Issue: 4
Pages: 1143-55
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Publication
28558959 | J:347889
 
First Author: Tanikawa C
Year: 2017
Journal: EBioMedicine
Title: The Transcriptional Landscape of p53 Signalling Pathway.
Volume: 20
Pages: 109-119
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Publication
19966213 | J:159427
First Author: Oracki SA
Year: 2010
Journal: J Immunol
Title: CTLA4Ig alters the course of autoimmune disease development in Lyn-/- mice.
Volume: 184
Issue: 2
Pages: 757-63
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Publication
25801896 | J:249111
First Author: Shen H
Year: 2015
Journal: Circ Res
Title: Haptoglobin enhances cardiac transplant rejection.
Volume: 116
Issue: 10
Pages: 1670-9
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Publication
35831019 | J:327307
First Author: Pan W
Year: 2022
Journal: J Immunol
Title: PPP2R2D Suppresses Effector T Cell Exhaustion and Regulatory T Cell Expansion and Inhibits Tumor Growth in Melanoma.
Volume: 209
Issue: 3
Pages: 621-628
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Publication
28685773 | J:331306
First Author: Lee YH
Year: 2017
Journal: Cell Res
Title: Inhibition of the B7-H3 immune checkpoint limits tumor growth by enhancing cytotoxic lymphocyte function.
Volume: 27
Issue: 8
Pages: 1034-1045
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Publication
36525476 | J:333515
First Author: Dhanasekaran R
Year: 2023
Journal: Cancer Res
Title: MYC Overexpression Drives Immune Evasion in Hepatocellular Carcinoma That Is Reversible through Restoration of Proinflammatory Macrophages.
Volume: 83
Issue: 4
Pages: 626-640
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Publication
19276342 | J:147077
First Author: Ozao-Choy J
Year: 2009
Journal: Cancer Res
Title: The novel role of tyrosine kinase inhibitor in the reversal of immune suppression and modulation of tumor microenvironment for immune-based cancer therapies.
Volume: 69
Issue: 6
Pages: 2514-22
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Publication
17710230 | J:127409
First Author: Sharma MD
Year: 2007
Journal: J Clin Invest
Title: Plasmacytoid dendritic cells from mouse tumor-draining lymph nodes directly activate mature Tregs via indoleamine 2,3-dioxygenase.
Volume: 117
Issue: 9
Pages: 2570-82
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Publication
15967784 | J:99971
First Author: Baban B
Year: 2005
Journal: Int Immunol
Title: A minor population of splenic dendritic cells expressing CD19 mediates IDO-dependent T cell suppression via type I IFN signaling following B7 ligation.
Volume: 17
Issue: 7
Pages: 909-19
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Publication
27634762 | J:236856
First Author: Ngiow SF
Year: 2016
Journal: Cancer Res
Title: Agonistic CD40 mAb-Driven IL12 Reverses Resistance to Anti-PD1 in a T-cell-Rich Tumor.
Volume: 76
Issue: 21
Pages: 6266-6277
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Publication
35603158 | J:325071
 
First Author: Sudan R
Year: 2022
Journal: Front Immunol
Title: LRBA Deficiency Can Lead to Lethal Colitis That Is Diminished by SHIP1 Agonism.
Volume: 13
Pages: 830961
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Publication
11735222 | J:73271
First Author: Ling V
Year: 2001
Journal: Genomics
Title: Assembly and annotation of human chromosome 2q33 sequence containing the CD28, CTLA4, and ICOS gene cluster: analysis by computational, comparative, and microarray approaches.
Volume: 78
Issue: 3
Pages: 155-68
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Publication
10779758 | J:61707
First Author: Yu XZ
Year: 2000
Journal: J Immunol
Title: CD28-specific antibody prevents graft-versus-host disease in mice.
Volume: 164
Issue: 9
Pages: 4564-8
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Publication
7514631 | J:18346
First Author: Larsen CP
Year: 1994
Journal: J Immunol
Title: Regulation of immunostimulatory function and costimulatory molecule (B7-1 and B7-2) expression on murine dendritic cells.
Volume: 152
Issue: 11
Pages: 5208-19
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Publication
7515912 | J:18631
First Author: Stack RM
Year: 1994
Journal: J Immunol
Title: IL-4 treatment of small splenic B cells induces costimulatory molecules B7-1 and B7-2.
Volume: 152
Issue: 12
Pages: 5723-33
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Publication
7519245 | J:19434
First Author: Hathcock KS
Year: 1994
Journal: J Exp Med
Title: Comparative analysis of B7-1 and B7-2 costimulatory ligands: expression and function.
Volume: 180
Issue: 2
Pages: 631-40
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Publication
9761724 | J:50458
 
First Author: Ellis JH
Year: 1998
Journal: Biochem J
Title: Functional analysis of the T-cell-restricted protein tyrosine kinase Txk.
Volume: 335 ( Pt 2)
Pages: 277-84
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Publication
12097374 | J:77746
First Author: Yen MH
Year: 2002
Journal: J Immunol
Title: Induction of CD4 T cell changes in murine AIDS is dependent on costimulation and involves a dysregulation of homeostasis.
Volume: 169
Issue: 2
Pages: 722-31
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Publication
15210770 | J:90933
First Author: Greve B
Year: 2004
Journal: J Immunol
Title: The diabetes susceptibility locus Idd5.1 on mouse chromosome 1 regulates ICOS expression and modulates murine experimental autoimmune encephalomyelitis.
Volume: 173
Issue: 1
Pages: 157-63
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Publication
25082815 | J:215983
First Author: Zhu Y
Year: 2014
Journal: Cancer Res
Title: CSF1/CSF1R blockade reprograms tumor-infiltrating macrophages and improves response to T-cell checkpoint immunotherapy in pancreatic cancer models.
Volume: 74
Issue: 18
Pages: 5057-69
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Publication
26854930 | J:232425
First Author: Jacquelot N
Year: 2016
Journal: J Clin Invest
Title: Chemokine receptor patterns in lymphocytes mirror metastatic spreading in melanoma.
Volume: 126
Issue: 3
Pages: 921-37
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Publication
30530991 | J:270931
First Author: Pai CS
Year: 2019
Journal: J Clin Invest
Title: Tumor-conditional anti-CTLA4 uncouples antitumor efficacy from immunotherapy-related toxicity.
Volume: 129
Issue: 1
Pages: 349-363
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Publication
34220851 | J:341880
 
First Author: Spinelli L
Year: 2021
Journal: Front Immunol
Title: Phosphoinositide 3-Kinase p110 Delta Differentially Restrains and Directs Naïve Versus Effector CD8(+) T Cell Transcriptional Programs.
Volume: 12
Pages: 691997
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Publication
38226924 | J:360606
First Author: Paterson CW
Year: 2024
Journal: Immunohorizons
Title: CTLA-4 Checkpoint Inhibition Improves Sepsis Survival in Alcohol-Exposed Mice.
Volume: 8
Issue: 1
Pages: 74-88
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Protein Coding Gene
MGI:1345147 | Akt3
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:2388481 | Ppp2r5d
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:99511 | Ptpn11
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:104874 | Akt2
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein
Q9WUA6
Organism: Mus musculus/domesticus
Length: 479  
Fragment?: false
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Protein
Q60823
Organism: Mus musculus/domesticus
Length: 481  
Fragment?: false
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Protein
P35235
Organism: Mus musculus/domesticus
Length: 593  
Fragment?: false
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Protein
Q7TNL5
Organism: Mus musculus/domesticus
Length: 595  
Fragment?: false
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Publication
10502560 | J:59459
First Author: Mathur M
Year: 1999
Journal: Am J Respir Cell Mol Biol
Title: CD28 interactions with either CD80 or CD86 are sufficient to induce allergic airway inflammation in mice.
Volume: 21
Issue: 4
Pages: 498-509
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Publication
23812589 | J:204754
First Author: Zeng H
Year: 2013
Journal: Nature
Title: mTORC1 couples immune signals and metabolic programming to establish T(reg)-cell function.
Volume: 499
Issue: 7459
Pages: 485-90
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Publication
21779410 | J:174933
First Author: Persson J
Year: 2011
Journal: PLoS One
Title: Immuno-therapy with anti-CTLA4 antibodies in tolerized and non-tolerized mouse tumor models.
Volume: 6
Issue: 7
Pages: e22303
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Publication
36202057 | J:353124
 
First Author: Chen FY
Year: 2022
Journal: Phytomedicine
Title: Distepharinamide, a novel dimeric proaporphine alkaloid from Diploclisia glaucescens, inhibits the differentiation and proliferative expansion of CD4(+)Foxp3(+) regulatory T cells.
Volume: 107
Pages: 154482
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Publication
36685883 | J:332809
 
First Author: Zhou Z
Year: 2022
Journal: Front Genet
Title: Pan-cancer analysis of the prognostic and immunological role of Fanconi anemia complementation group E.
Volume: 13
Pages: 1024989
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Publication
9686568 | J:48877
First Author: Issazadeh S
Year: 1998
Journal: J Immunol
Title: Kinetics of expression of costimulatory molecules and their ligands in murine relapsing experimental autoimmune encephalomyelitis in vivo.
Volume: 161
Issue: 3
Pages: 1104-12
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Publication
29995930 | J:263846
First Author: Salloum N
Year: 2018
Journal: PLoS One
Title: Epstein-Barr virus DNA modulates regulatory T-cell programming in addition to enhancing interleukin-17A production via Toll-like receptor 9.
Volume: 13
Issue: 7
Pages: e0200546
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Publication
37162929 | J:356834
     
First Author: Ma P
Year: 2023
Journal: bioRxiv
Title: Expansion of Disease Specific Cardiac Macrophages in Immune Checkpoint Inhibitor Myocarditis.
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Protein Coding Gene
MGI:87986 | Akt1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:98397 | Src
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1321161 | Ppp2cb
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1920949 | Ppp2r1b
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein
Q7TNP2
Organism: Mus musculus/domesticus
Length: 601  
Fragment?: false
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Protein
P31750
Organism: Mus musculus/domesticus
Length: 480  
Fragment?: false
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Protein
P05480
Organism: Mus musculus/domesticus
Length: 535  
Fragment?: false
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Protein
P62715
Organism: Mus musculus/domesticus
Length: 309  
Fragment?: false
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Protein Coding Gene
MGI:1321159 | Ppp2ca
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1926334 | Ppp2r1a
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein
Q76MZ3
Organism: Mus musculus/domesticus
Length: 589  
Fragment?: false
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Protein
P63330
Organism: Mus musculus/domesticus
Length: 309  
Fragment?: false
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

© 2002 - 2017 Department of Genetics, University of Cambridge, Downing Street,
Cambridge CB2 3EH, United Kingdom